Details of the Drug

General Information of Drug (ID: DM8SU6N)

Drug Name
LY-2183240
Synonyms
LY2183240; 874902-19-9; LY 2183240; UNII-2WBU91OKM7; 2WBU91OKM7; CHEMBL509860; LY-2183240; 5-Biphenyl-4-ylmethyl-tetrazole-1-carboxylic acid dimethylamide; LY2183240/LY-2183240; 1H-Tetrazole-1-carboxamide, 5-([1,1'-biphenyl]-4-ylmethyl)-N,N-dimethyl-; 1H-Tetrazole-1-carboxamide, 5-((1,1'-biphenyl)-4-ylmethyl)-N,N-dimethyl-; SCHEMBL2184828; CTK8E8366; CHEBI:92670; KS-00001CUG; BDBM26736; AOB2582; MolPort-023-219-146; HMS3269E15; BCP22610; ZINC13813297; MFCD08703123; 3796AH; AKOS024457108; CS-0913; BCP9000870; LP01268; NCGC00159571-01
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 307.35
Logarithm of the Partition Coefficient (xlogp) 3
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C17H17N5O
IUPAC Name
N,N-dimethyl-5-[(4-phenylphenyl)methyl]tetrazole-1-carboxamide
Canonical SMILES
CN(C)C(=O)N1C(=NN=N1)CC2=CC=C(C=C2)C3=CC=CC=C3
InChI
InChI=1S/C17H17N5O/c1-21(2)17(23)22-16(18-19-20-22)12-13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3
InChIKey
GZNIYOXWFCDBBJ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11507802
ChEBI ID
CHEBI:92670
CAS Number
874902-19-9
UNII
2WBU91OKM7
DrugBank ID
DB17035
TTD ID
D0W7XR

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fatty acid amide hydrolase (FAAH) TTDP1UC NOUNIPROTAC Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Fatty acid amide hydrolase (FAAH) DTT NO-GeName 2.65E-01 0.02 0.1
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 151 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 0.8646 1.6471 0.8646 27.8463
JK1 CTRP2 1.9433 3.8622 1.8946 20.8246
JM1 CTRP2 0.3481 1.7687 0.3472 31.2901
HuT 78 CTRP2 -2.1302 13.0154 -5.8134 48.9073
AML-193 CTRP2 -1.4745 3.7396 -1.7608 43.9768
ALL-SIL CTRP2 -0.6861 1.1674 -0.688 38.1835
Peer CTRP2 -0.6416 0.0476 -0.6416 37.8808
RPMI-8402 CTRP2 -0.5637 0.2682 -0.5637 37.3622
M-07e CTRP2 -0.5536 0.9221 -0.5539 37.2958
SEM CTRP2 -0.518 0.2347 -0.518 37.0578
P31/FUJ CTRP2 -0.5079 0.1745 -0.5079 36.99
KMS-34 CTRP2 -0.4435 0.0521 -0.4435 36.561
KMS-11 CTRP2; CTRP1 -0.3958 1.0119 -0.396 36.3055
GDM-1 CTRP2; CTRP1 -0.31 0.9076 -0.3101 35.7342
NU-DUL-1 CTRP2; CTRP1 -0.2234 1.5762 -0.226 35.1661
OCI-AML-3 CTRP2; CTRP1 -0.2128 0.7538 -0.2128 35.0866
CML-T1 CTRP2 -0.1531 1.3504 -0.1538 34.6288
P12-Ichikawa CTRP2 -0.0403 0.8061 -0.0403 33.8748
SUP-T1 CTRP2 0.0019 1.4063 0.0014 33.5958
KMS-12-BM CTRP2 0.0394 1.0912 0.0394 33.3439
KM-H2 CTRP2 0.0553 1.1758 0.0552 33.2384
Kasumi-2 CTRP2 0.0585 1.1073 0.0585 33.2168
KE-37 CTRP2 0.0954 1.1121 0.0954 32.9707
NALM-6 CTRP2 0.1038 0.9664 0.1038 32.9146
PL21 CTRP2; CTRP1 0.1239 0.9906 0.1239 32.8456
OPM-2 CTRP2 0.1261 1.2118 0.1261 32.7665
A4/Fukuda CTRP2 0.1331 2.253 0.1213 32.7593
KE-97 CTRP2; CTRP1 0.151 1.4379 0.1507 32.6665
DB CTRP2 0.1692 1.9919 0.1646 32.4944
BL-70 CTRP2; CTRP1 0.185 0.8108 0.185 32.439
PF-382 CTRP2 0.2148 1.5796 0.2142 32.1774
KMS-26 CTRP2 0.2169 0.968 0.2169 32.1617
WSU-DLCL2 CTRP2; CTRP1 0.2415 0.8162 0.2415 32.0634
NU-DHL-1 CTRP2 0.2435 1.4091 0.2433 31.985
SUP-M2 CTRP2 0.3341 1.2311 0.3341 31.3806
JeKo-1 CTRP2 0.362 0.936 0.362 31.195
MOLT-3 CTRP2 0.3624 0.9089 0.3624 31.192
SKM-1 CTRP2; CTRP1 0.3818 0.9265 0.3818 31.1292
Jurkat CTRP2 0.386 1.2578 0.386 31.0347
Reh CTRP2 0.3877 1.0698 0.3877 31.0235
697 CTRP2 0.3943 1.3334 0.3943 30.9798
ST486 CTRP2 0.4246 1.181 0.4246 30.778
SUP-T11 CTRP2 0.4305 2.5432 0.4148 30.7906
Daudi CTRP2 0.4504 1.2338 0.4504 30.6058
HT CTRP2; CTRP1 0.4539 1.333 0.4539 30.6492
Namalwa CTRP2 0.4581 1.2235 0.4581 30.5545
MJ CTRP2 0.4631 5.8554 -0.1982 32.6403
Karpas-299 CTRP2 0.4898 1.8172 0.4891 30.3456
RCH-ACV CTRP2 0.5038 1.7154 0.5036 30.2508
GA-10 CTRP2 0.5122 1.1173 0.5122 30.194
EoL-1 CTRP2 0.534 1.1092 0.534 30.049
KO52 CTRP2 0.5375 1.1142 0.5375 30.0253
MOTN-1 CTRP2 0.5432 1.8932 0.5424 29.9902
MV4-11 CTRP2 0.544 1.2689 0.544 29.9822
JVM-2 CTRP2 0.5499 3.6926 0.4314 30.3397
K-562 CTRP2 0.5655 1.3571 0.5655 29.8392
CA46 CTRP2 0.5756 2.7817 0.5524 29.8493
Pfeiffer CTRP2 0.5858 1.5907 0.5858 29.7039
HPB-ALL CTRP2 0.5985 1.8209 0.5981 29.6206
MOLM-16 CTRP2; CTRP1 0.5997 1.5933 0.5996 29.6794
DND-41 CTRP2 0.6028 4.0063 0.436 30.1499
Ci-1 CTRP2 0.6169 1.245 0.6169 29.4965
EB1 CTRP2 0.6202 1.7829 0.6199 29.4756
Ki-JK CTRP2 0.6237 2.4106 0.6166 29.475
EJM CTRP2; CTRP1 0.639 1.8925 0.6385 29.4195
Mino CTRP2 0.6584 4.7383 0.3378 30.2939
NCO2 CTRP2 0.6785 2.0226 0.6775 29.0896
TALL-1 [Human adult T-ALL] CTRP2 0.7288 3.6273 0.6323 29.0759
CMK CTRP2 0.7404 1.625 0.7404 28.6739
L-428 CTRP2 0.7491 2.983 0.7198 28.7142
F-36P CTRP2 0.7619 2.2293 0.7597 28.5376
NB4 CTRP2 0.7827 1.257 0.7827 28.3922
SUP-HD1 CTRP2 0.7916 2.8653 0.771 28.4019
LP-1 CTRP2; CTRP1 0.8174 3.226 0.7726 28.3805
Ri-1 CTRP2 0.8211 2.3057 0.8185 28.145
SU-DHL-5 CTRP1 0.8312 1.4438 0.8312 60.3959
Raji CTRP2 0.8363 1.6843 0.8363 28.0347
Granta-519 CTRP2 0.8603 2.3404 0.8576 27.884
Ku812 CTRP2; CTRP1 0.9133 2.3609 0.9109 27.5998
KMS-21-BM CTRP2 0.9336 1.8844 0.9335 27.3872
KMS-20 CTRP2 0.9482 2.4339 0.9451 27.2998
SUP-B15 CTRP2 0.9506 1.8298 0.9506 27.2733
KMS-18 CTRP2 0.9623 2.3006 0.9608 27.2006
BV-173 CTRP2 0.9792 2.3742 0.9771 27.0901
MOLM-6 CTRP2 1.0081 2.9669 0.989 26.9543
MOLT-13 CTRP2 1.0259 2.1021 1.0257 26.7725
HEL CTRP2 1.0866 1.8911 1.0866 26.3673
Hs 611.T CTRP2 1.0917 3.5995 1.0223 26.5676
KMS-27 CTRP2 1.0945 2.1292 1.0943 26.3155
L-540 CTRP2 1.1047 2.378 1.1034 26.2511
KHM-1B CTRP2 1.1198 2.9326 1.0758 21.2757
RL CTRP2 1.1717 2.7864 1.1642 25.8254
DoHH2 CTRP2 1.1745 2.7702 1.1675 25.805
MOLT-16 CTRP2 1.2456 2.1124 1.2456 25.3081
U-937 CTRP2; CTRP1 1.2529 1.8718 1.2529 25.3316
LAMA-84 CTRP2 1.2615 2.3486 1.261 25.2037
NCI-H929 CTRP2 1.2668 3.1532 1.246 25.2366
TF-1 CTRP2 1.285 6.039 0.6327 27.3024
SU-DHL-6 CTRP2 1.3007 2.4839 1.2997 24.9442
HEL 92.1.7 CTRP2 1.3055 2.34 1.3052 24.9099
NOMO-1 CTRP2; CTRP1 1.3231 2.9067 1.3151 24.891
KMS-28BM CTRP2 1.3293 3.7439 1.2569 24.9954
THP-1 CTRP2; CTRP1 1.3439 2.8239 1.3385 24.7437
EM-2 CTRP2 1.348 2.1444 1.348 24.6257
HuNS1 CTRP2 1.3596 2.6609 1.3573 24.5562
HDLM-2 CTRP2 1.3956 4.0586 1.2817 24.6965
HD-MY-Z CTRP2 1.3989 5.2893 0.9965 25.6842
MOLP-8 CTRP2 1.4289 3.7457 1.3626 24.3112
Kasumi-1 CTRP2 1.435 2.256 1.4349 24.0466
SR CTRP2 1.4395 3.139 1.425 24.0647
SET-2 CTRP2 1.4556 3.0573 1.4451 23.944
MC116 CTRP2; CTRP1 1.456 1.9566 1.456 23.9795
A3/Kawakami CTRP2 1.4642 1.89 1.4642 23.852
Karpas-422 CTRP2 1.5013 2.1384 1.5012 23.6049
SU-DHL-1 CTRP2 1.5096 3.457 1.4774 23.6574
U266B1 CTRP2 1.5166 4.2591 1.3768 23.9805
JURL-MK1 CTRP2 1.519 2.2242 1.519 23.4866
DEL CTRP2 1.5443 1.9233 1.5443 23.3181
SIG-M5 CTRP2 1.5499 1.896 1.5499 23.2808
OCI-AML-2 CTRP2 1.5644 2.0412 1.5644 23.1841
KCL-22 CTRP2 1.5685 2.3163 1.5685 23.1567
RPMI-8226 CTRP2; CTRP1 1.5716 2.3448 1.5715 23.2107
HL-60 CTRP2 1.5748 2.0048 1.5748 23.1147
Mono-Mac-1 CTRP2 1.6001 4.3515 1.4495 23.4622
RPMI-6666 CTRP2 1.6073 2.147 1.6073 22.8983
JJN-3 CTRP2 1.6094 2.6173 1.6089 22.8859
SU-DHL-8 CTRP2 1.6191 3.6225 1.5775 22.9599
OCI-Ly19 CTRP2 1.6194 2.7844 1.6177 22.8235
OCI-M1 CTRP2 1.6283 3.1334 1.619 22.7895
EHEB CTRP2 1.63 3.5222 1.5979 22.855
MHH-CALL-4 CTRP2 1.6389 2.7161 1.638 22.6909
OCI-Ly3 CTRP2 1.6737 2.2715 1.6737 22.456
MM1.S CTRP2 1.6897 2.4314 1.6897 22.3494
KYO-1 CTRP2 1.6979 3.1151 1.6907 22.3188
MOLM-13 CTRP2 1.7268 2.9244 1.7243 22.1104
OCI-AML-5 CTRP2 1.7447 2.239 1.7447 21.9827
L-1236 CTRP2 1.7464 6.7049 0.8865 25.024
JVM-3 CTRP2 1.7658 4.2405 1.5103 17.4807
SU-DHL-10 CTRP2 1.7962 2.9823 1.7936 21.6484
L-363 CTRP2 1.8411 2.9316 1.8396 21.3458
MOLP-2 CTRP2 1.8582 3.8504 1.8057 21.4043
SU-DHL-4 CTRP2; CTRP1 2.0229 3.0451 2.0215 20.2113
P3HR-1 CTRP2; CTRP1 2.0729 3.2986 2.0676 19.8917
ME1 CTRP2 2.1172 4.5129 1.9777 19.9807
MHH-CALL-3 CTRP2 2.2929 6.3431 1.6086 20.8048
AMO1 CTRP2; CTRP1 2.4671 3.1116 2.467 17.2506
OCI-Ly10 CTRP2; CTRP1 2.708 4.1191 2.6758 15.7553
REC-1 CTRP2 4.1354 5.2027 4.0051 6.5189
Mono-Mac-6 CTRP2 4.1409 7.0345 3.2234 9.5973
Toledo CTRP2 4.394 5.9792 3.9651 5.9708
Karpas-620 CTRP2 6.065 8.1369 4.2432 1.8331
⏷ Show the Full List of 151 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 2.3401 8.199 0.8857 23.3388
TE-5 CTRP2 2.2424 5.2625 1.9243 19.7866
TE-14 CTRP2 2.3113 4.8275 2.118 18.8793
KYSE-410 CTRP2; CTRP1 2.3817 5.166 2.1072 18.7809
KYSE-180 CTRP2 2.5407 4.1571 2.4933 16.8401
TE-9 CTRP2 2.5781 4.0946 2.5404 16.558
KYSE-70 CTRP2 2.608 4.7863 2.4512 16.7746
TE-10 CTRP2 2.7159 4.772 2.5721 16.0101
KYSE-510 CTRP2 2.9389 6.3947 2.2758 16.4641
OE21 CTRP2 2.9967 5.3134 2.7308 14.5832
KYSE-140 CTRP2; CTRP1 3.1036 7.3822 2.0332 17.0438
TE-11 CTRP2 3.3693 5.8959 2.9295 12.7639
EC-GI-10 CTRP2 3.7254 6.8493 2.8969 11.9428
KYSE-150 CTRP2 3.9273 8.5778 2.2781 13.9601
KYSE-450 CTRP2; CTRP1 4.2909 8.777 2.5266 12.2013
KYSE-520 CTRP2 5.1064 10.4038 2.4161 10.8975
TE-1 CTRP2 5.252 8.1214 3.6753 5.3666
OE19 CTRP2 5.5817 13.243 1.3838 14.1132
OE33 CTRP2 5.9021 9.2746 3.5945 4.6246
COLO 680N CTRP2 5.9697 8.799 3.871 3.4061
KYSE-30 CTRP2 6.2415 11.5465 2.7289 7.6317
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 5.0047 8.9621 3.0524 8.447
KP-4 CTRP2 1.3154 4.4781 1.1143 25.5324
PaTu 8988t CTRP2 1.5235 12.2744 -1.8038 33.4144
BxPC-3 CTRP2 1.6181 4.0693 1.5192 23.1632
MIA PaCa-2 CTRP2 1.6973 3.4436 1.6741 22.3767
PSN1 CTRP2 1.9872 6.7201 1.1372 23.4207
QGP-1 CTRP2; CTRP1 2.6073 6.4311 1.9146 18.8417
PANC-1 CTRP2 2.9647 6.6946 2.1802 16.7621
HuP-T4 CTRP2; CTRP1 3.429 8.1242 2.0209 16.2655
KP-3 CTRP2; CTRP1 3.5991 7.8639 2.31 14.6936
Panc 03.27 CTRP2; CTRP1 3.7162 7.561 2.5669 13.3735
L3.3 CTRP2 3.8089 5.8849 3.4004 9.7379
YAPC CTRP2 4.1864 7.3068 3.1375 9.8407
Panc 08.13 CTRP2 4.2065 9.186 2.2396 13.484
SW1990 CTRP2 4.3052 9.5497 2.1496 13.6338
PK-59 CTRP2 4.3863 7.9522 3.0112 9.9058
Hs 766T CTRP2 4.4011 9.2093 2.4042 12.3845
Capan-1 CTRP2 4.5461 10.8891 1.697 14.9368
Panc 10.05 CTRP2; CTRP1 4.5866 10.5197 1.9255 14.0161
HuP-T3 CTRP2 4.9912 8.6879 3.1781 7.9465
SUIT-2 CTRP2; CTRP1 5.0722 7.2542 3.9723 4.5372
PaTu 8988s CTRP2 5.197 10.51 2.4377 10.6357
PK-45H CTRP2 5.2321 9.4227 3.0097 8.1928
PaTu 8902 CTRP2; CTRP1 5.3322 12.7769 1.4252 14.4943
HPAF-II CTRP2 5.5143 8.2961 3.0198 2.5284
DAN-G CTRP2 5.9557 25.2326 -4.3007 28.7372
Panc 05.04 CTRP2 6.1515 9.8433 3.4932 4.6669
TCC-Pan2 CTRP2 6.3748 11.0035 3.0875 5.9789
KP-2 CTRP2 6.4752 10.7307 3.2871 5.036
Capan-2 CTRP2; CTRP1 6.5744 12.1009 2.7069 7.2855
SNU-213 CTRP2 6.6692 11.5013 3.0491 5.7131
CFPAC-1 CTRP2; CTRP1 6.8266 8.5037 4.4931 0.4781
AsPC-1 CTRP2 7.0989 19.8698 -0.7335 18.5956
HPAC CTRP2; CTRP1 7.2323 12.5462 2.9344 5.4846
Panc 02.03 CTRP2 7.4009 13.9368 2.3754 7.3447
Panc 04.03 CTRP2 7.4174 15.4559 1.659 10.0401
SNU-410 CTRP2 8.0518 18.6644 0.5487 13.0584
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.7935 9.9798 3.1697 7.5632
CJM [Human melanoma] CTRP2 0.5362 1.1719 0.5362 30.0345
COLO 741 CTRP1 0.6452 3.6267 0.5441 61.0977
LOX-IMVI CTRP2 1.4222 3.61 1.3711 24.3037
Mel Ho CTRP2 1.4274 3.5253 1.3851 24.2394
HMCB CTRP2 1.701 4.307 1.5673 22.7317
IGR-37 CTRP2 1.8124 2.8405 1.8115 21.5352
A2058 CTRP2 1.846 4.1469 1.7516 21.6295
Mel JuSo CTRP2 1.8981 3.3938 1.8848 21.0055
SK-MEL-5 CTRP2; CTRP1 1.9414 5.4891 1.5302 22.1976
RPMI-7951 CTRP2 2.323 4.1851 2.2573 18.3534
RVH-421 CTRP2 2.3347 4.8724 2.1324 18.7556
Hs 944.T CTRP2; CTRP1 2.4767 4.5181 2.368 17.5586
WM1799 CTRP2 2.5294 4.8643 2.3467 17.39
A-375 CTRP2; CTRP1 2.5637 5.385 2.2403 17.7505
G-361 CTRP2; CTRP1 2.6821 4.9352 2.4978 16.46
WM88 CTRP2 2.7229 7.8882 1.414 20.3545
Hs 852.T CTRP2; CTRP1 2.8147 5.8384 2.36 16.5734
Hs 294T CTRP2 3.3073 5.9393 2.8466 13.254
MeWo CTRP2 3.4771 7.0471 2.5565 13.934
Hs 936.T CTRP2; CTRP1 3.5097 7.6885 2.3034 14.941
MDA-MB-435S CTRP2 3.6897 7.0199 2.7836 12.4867
COLO 792 CTRP2 3.7203 13.5498 -0.3565 24.0274
WM983B CTRP2 3.8755 8.2756 2.3748 13.6883
IGR-1 CTRP2 3.926 7.0745 2.9939 11.0514
WM793 CTRP2 3.9474 6.2827 3.3757 9.4658
COLO 800 CTRP2 4.001 13.3751 -0.0195 22.3323
WT2-iPS CTRP2 4.0231 11.6906 0.8361 19.346
Hs 934.T CTRP2 4.3707 10.7628 1.606 15.668
HT-144 CTRP2 4.4596 8.0502 3.03 9.6662
WM115 CTRP2 4.5092 9.2608 2.4751 11.8611
K029AX CTRP2 4.6465 7.5396 3.4515 7.5051
COLO 829 CTRP2 4.7004 15.1308 -0.2883 21.6801
SK-MEL-1 CTRP2; CTRP1 4.9793 10.5658 2.2388 11.9492
SK-MEL-2 CTRP2 5.1689 7.6497 3.844 4.8107
IPC-298 CTRP2 5.1959 8.4168 3.4828 6.2772
SK-MEL-3 CTRP2 5.2513 10.3805 2.5467 10.0831
IGR-39 CTRP2 5.6248 40.2712 -12.0877 37.6719
SK-MEL-30 CTRP2 5.7797 10.8924 2.7083 8.4708
WM266-4 CTRP2 6.0184 11.8559 2.4123 9.2768
Hs 688(A).T CTRP2 6.0678 10.3549 3.1862 6.0396
Hs 940.T CTRP2 6.3484 15.6258 0.7972 14.9042
SK-MEL-31 CTRP2 6.476 10.9345 3.1901 5.4218
SK-MEL-28 CTRP2; CTRP1 6.6159 7.6131 4.737 0.0962
SK-MEL-24 CTRP2 7.0124 14.3644 1.9052 9.7073
Hs 839.T CTRP2 7.301 18.0395 0.3181 14.9741
UACC-257 CTRP2 7.5487 13.59 2.6348 6.1605
Hs 895.T CTRP2 7.6897 14.7103 2.1982 7.6327
UACC-62 CTRP2 8.2147 15.5223 2.1529 7.1309
A101D CTRP2 10.3102 31.612 -4.1477 22.0597
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-SH CTRP2 -0.4446 5.9216 -1.2065 38.5642
MHH-NB-11 CTRP2 -0.0442 1.0746 -0.0442 33.9009
IMR-32 CTRP2 0.0964 3.1654 0.0178 33.2229
SK-N-BE(2) CTRP2 0.1071 3.0874 0.0376 33.122
Kelly CTRP2 0.3414 1.0657 0.3414 31.3319
SK-N-DZ CTRP2 0.5314 4.1585 0.3297 30.7397
CHP-212 CTRP2 0.5939 2.7011 0.5756 29.7111
SK-N-FI CTRP2 0.7565 3.9715 0.6081 29.067
NB1 CTRP2 0.959 1.7621 0.9589 27.2178
NH-6 CTRP2 1.0295 4.0689 0.8854 27.237
KP-N-SI9s CTRP2 1.6741 3.0706 1.6678 22.4747
CHP-126 CTRP2 1.841 3.0688 1.8373 21.3538
SK-N-AS CTRP2 2.1208 5.443 1.7367 20.8344
KP-N-YN CTRP2 3.8077 7.0859 2.8714 11.8385
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 2.573 5.0917 2.3342 17.3013
SNU-1079 CTRP2 3.842 8.4481 2.2599 14.233
HuCC-T1 CTRP2 3.9614 6.8876 3.1158 10.4714
SNU-1196 CTRP2 4.3237 7.4241 3.2111 9.2194
HuH-28 CTRP2 4.6028 8.5955 2.8886 9.9475
SNU-308 CTRP2 4.7403 7.3361 3.6362 6.5333
SNU-869 CTRP2 5.195 12.4746 1.4541 14.5771
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-ES-1 CTRP2 -0.0629 0.9626 -0.0629 34.0257
SK-N-MC CTRP2 0.4795 0.9336 0.4795 30.4118
A-673 CTRP2 0.5737 1.2523 0.5737 29.7846
MHH-ES-1 CTRP2 1.0993 2.3503 1.0982 26.2865
TC71 CTRP2 1.5603 2.0029 1.5603 23.2117
SaOS-2 CTRP2 1.5832 2.8569 1.5802 23.0691
G-292 clone A141B1 CTRP2 2.0627 4.1909 1.9773 20.1552
HOS CTRP2 2.2661 6.0407 1.6919 20.5717
U2OS CTRP2; CTRP1 3.0009 6.2045 2.4219 15.8126
SW1353 CTRP2 3.1511 7.3585 2.086 16.6348
Hs 888.T CTRP2 4.2545 7.7928 2.9669 10.3852
MG-63 CTRP2 4.5634 10.4984 1.9069 14.0641
Hs 822.T CTRP2 5.4631 8.1711 3.8148 4.4145
CAL-78 CTRP2 5.6848 11.5165 2.3254 10.2027
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 70 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-157 CTRP2 -0.5138 3.8487 -0.8709 33.949
HCC1500 CTRP2 -0.2268 8.1756 -1.7874 38.9214
DU4475 CTRP2 0.4655 1.0947 0.4655 30.5051
HMC-1-8 CTRP2 1.4137 2.3029 1.4136 24.1888
SK-BR-3 CTRP2 1.8377 4.9138 1.5796 22.2609
AU565 CTRP2 2.4145 12.2631 -0.9372 28.897
CAL-148 CTRP2 2.4558 3.6957 2.4445 17.2835
CAL-51 CTRP2 2.5355 4.2181 2.4798 16.9036
HCC38 CTRP2 2.7116 6.5332 1.9799 18.2254
MDA-MB-468 CTRP2 2.817 6.9066 1.9371 18.1005
MCF-7 CTRP2; CTRP1 2.898 6.9281 2.018 17.6479
HCC2218 CTRP2 3.2324 6.0936 2.7067 13.9981
HCC1954 CTRP2 3.3944 5.4456 2.77 7.518
HCC1395 CTRP2 3.4774 5.146 3.3055 11.0444
HCC1806 CTRP2 3.6277 5.1257 3.4753 9.9741
BT-549 CTRP2 3.652 11.276 0.7037 20.6716
MDA-MB-453 CTRP2 3.6666 7.5431 2.5194 13.6058
JIMT-1 CTRP2 3.7135 5.3978 3.4822 9.695
HCC202 CTRP2 4.0323 8.5114 2.409 13.1848
CAL-85-1 CTRP2 4.1025 8.5964 2.4331 12.9263
MDA-MB-231 CTRP2 4.2819 7.5887 3.0918 9.8074
MDA-MB-361 CTRP2 4.4422 8.7883 2.6496 11.2832
EFM-192A CTRP2 4.4762 10.932 1.6146 15.409
BT-20 CTRP2 4.8003 9.9259 2.3974 11.5789
CAMA-1 CTRP2 4.8746 13.4531 0.6978 18.026
T-47D CTRP2 5.1748 8.1614 3.5932 5.8525
HDQ-P1 CTRP2 5.3452 8.407 3.6067 5.4866
CAL-120 CTRP2 5.3597 8.3821 3.6305 5.3616
BT-474 CTRP2 5.5923 8.8941 3.5549 5.2792
ZR-75-30 CTRP2 5.679 8.7637 3.6835 4.6058
ZR-75-1 CTRP2 5.7493 8.0043 4.1027 2.7865
HCC1419 CTRP2 5.7882 9.8264 3.2414 6.2559
HCC1143 CTRP2 5.8297 9.8716 3.2498 6.1539
KPL-1 CTRP2 6.3012 7.0934 4.789 0.0838
HCC1937 CTRP2 6.4855 10.3669 3.467 4.3091
HCC1428 CTRP2 7.8576 15.7983 1.7926 8.9239
BT 145 CTRP2 1.079 2.1727 1.0787 26.4189
BT 239 CTRP2 1.7021 4.1033 1.604 22.6011
BT 245 CTRP2 1.881 3.2682 1.8727 21.1028
BT 172 CTRP2 2.3 4.128 2.2407 18.4848
BT 231 CTRP2 2.3973 5.654 1.9688 19.1632
BT 286 CTRP2 2.7874 5.1371 2.5553 15.8512
BT 416 CTRP2 3.0001 4.4681 2.9403 13.8231
BT 112 CTRP2 3.2907 6.3428 2.6677 13.9886
BT147 CTRP2 3.2934 6.6925 2.5235 14.5437
BT 179 CTRP2 3.3351 7.1135 2.3824 14.9903
BT164 CTRP2 3.3978 6.8396 2.5675 14.0959
BT 271 CTRP2 3.44 6.4354 2.7853 13.1287
BT 228 CTRP2 3.5613 8.0975 2.1562 15.3229
BT 330 CTRP2 3.7227 7.1204 2.7708 12.4552
BT 224 CTRP2 3.7572 8.2394 2.2789 14.3569
BT 504 CTRP2 3.7695 6.2864 3.1909 10.6619
BT 359 CTRP2 3.882 9.5089 1.7823 16.0573
BT 131 CTRP2 4.0183 6.9831 3.1277 10.2833
BT 232 CTRP2 4.3773 6.1853 3.8539 6.4602
BT 248 CTRP2 4.6417 9.3431 2.5509 11.2695
BT 428 CTRP2 4.6716 8.5044 2.9947 9.3606
BT 422 CTRP2 4.731 8.4604 3.0687 8.9282
BT 139 CTRP2 4.8068 8.8993 2.9155 9.4133
BT 333 CTRP2 5.2029 8.3891 3.5022 6.1825
BT 440 CTRP2 5.3323 7.6078 3.994 3.8901
BT 320 CTRP2 5.4756 7.3607 4.223 2.704
BT 159 CTRP2 5.6682 10.9293 2.6043 9.0906
BT 216 CTRP2 5.6891 8.2492 3.9423 3.5263
BT 444 CTRP2 5.9691 9.6313 3.4685 5.0374
BT 340 CTRP2 6.0136 11.6289 2.5209 8.8444
BT 328 CTRP2 6.2064 9.5112 3.6894 3.8044
BT 498 CTRP2 6.4307 14.6462 1.3442 12.7656
BT 482 CTRP2 6.6952 11.6414 2.9995 5.8736
BT 187 CTRP2 7.4972 13.2663 2.7535 5.7744
⏷ Show the Full List of 70 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 1.8313 2.4653 1.8313 21.4061
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med CTRP2 0.651 1.4588 0.651 29.2692
YH-13 CTRP2 0.7472 5.2814 0.2879 30.1673
TM-31 CTRP2 0.7746 8.8958 -1.0312 33.8773
SF268 CTRP2 1.0824 4.1504 0.9277 26.9217
Becker CTRP2 1.1557 5.2128 0.7534 27.2901
SF539 CTRP2 1.2319 3.0405 1.2161 25.4522
Daoy CTRP2 1.5599 2.2542 1.5599 23.2143
M059K CTRP2 1.714 12.7121 -1.8256 32.9343
SNU-466 CTRP2 2.2272 4.2285 2.1481 19.0378
AM-38 CTRP2 2.2896 5.0004 2.0499 19.1899
ONS-76 CTRP2 2.3116 5.573 1.9025 19.66
A-172 CTRP2 2.3831 4.204 2.3188 17.9482
LN-18 CTRP2 2.4065 4.1211 2.3551 17.7482
Hs 683 CTRP2 2.4689 5.6961 2.0321 18.7188
LN-229 CTRP2; CTRP1 2.7188 5.8605 2.2486 17.2663
YKG-1 CTRP2 2.8732 6.0545 2.3388 16.4071
DK-MG CTRP2 2.9874 6.0953 2.4452 15.6814
42-MG-BA CTRP2 3.3351 6.8361 2.5046 14.5081
SF295 CTRP2; CTRP1 3.6718 7.1549 2.7106 12.9066
U-118MG CTRP2 3.7068 8.7593 1.9812 15.6735
KG-1-C CTRP2 3.7132 9.5622 1.5987 17.1721
SF126 CTRP2 3.8895 6.735 3.114 10.6582
GaMG CTRP2; CTRP1 4.0261 5.9836 3.5922 8.4921
DBTRG-05MG CTRP2 4.2044 7.0658 3.2701 9.255
GB-1 CTRP2 4.2385 8.1289 2.788 11.16
U-251MG CTRP2 4.2664 8.4575 2.6528 11.6552
KALS-1 CTRP2 4.3928 9.4333 2.2858 12.8885
SNB-75 CTRP2 4.7767 11.4695 1.6061 14.8175
SW1088 CTRP2 4.8587 7.2257 3.7954 5.6197
SNU-489 CTRP2 5.1321 7.9811 3.6485 5.7001
U-87MG ATCC CTRP2 5.1806 8.1568 3.6002 5.8125
GOS-3 CTRP2 5.2257 11.124 2.1543 11.7404
SNU-738 CTRP2 5.3352 8.3926 3.6061 5.5071
SNU-1105 CTRP2 5.3613 9.1954 3.2268 7.0483
CAS-1 CTRP2 5.4278 8.9209 3.4156 7.1019
CCF-STTG1 CTRP2 5.6106 10.9735 2.5375 9.4668
NMC-G1 CTRP2 5.812 9.4484 3.4448 5.3785
8-MG-BA CTRP2 6.0558 25.187 -4.197 28.3867
SNU-626 CTRP2 6.1511 8.0117 4.35 1.3512
SNU-201 CTRP2 6.6875 8.1163 4.5682 0.3331
KNS-42 CTRP2 6.9562 15.0258 1.5433 11.1681
T98G CTRP2 7.7023 15.409 1.8747 8.8306
SW1783 CTRP2 7.7631 28.6677 -4.5851 26.382
GMS-10 CTRP2 7.8644 25.7905 -3.0825 23.298
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 0.3218 3.9806 0.1386 32.1321
JHUEM-7 CTRP2 1.0932 4.8646 0.7801 27.3957
RL95-2 CTRP2 1.4282 2.7486 1.4252 24.1017
JHUEM-1 CTRP2 1.8378 2.2927 1.8378 21.3631
MFE-319 CTRP2; CTRP1 1.8924 4.5726 1.7228 21.659
HEC-151 CTRP2; CTRP1 1.9038 3.4887 1.8859 21.0594
MFE-296 CTRP2 1.9273 5.8163 1.4044 22.6225
HEC-251 CTRP2; CTRP1 1.9558 4.6161 1.7822 21.2512
HEC-108 CTRP2; CTRP1 2.436 4.7849 2.2664 18.0438
KLE CTRP2; CTRP1 2.5889 6.8591 1.7232 19.6184
AN3-CA CTRP2 3.0374 7.3404 1.978 17.3544
HEC-265 CTRP2; CTRP1 3.0514 4.8167 2.9291 13.7839
JHUEM-3 CTRP2 3.3265 8.4752 1.7486 17.5162
HEC-6 CTRP2; CTRP1 3.5947 7.2259 2.6008 13.5396
ESS-1 CTRP2 3.6278 6.1555 3.0988 11.4003
HEC-1-A CTRP2 4.2977 7.6033 3.0996 9.7391
HEC-50B CTRP2 4.425 7.6092 3.2152 8.9738
HEC-59 CTRP2; CTRP1 4.437 7.874 3.1045 9.4896
HEC-1-B CTRP2 4.4668 9.4946 2.3213 12.5844
EFE-184 CTRP2 5.5933 8.2659 3.8651 3.9929
EN CTRP2 8.2034 16.812 1.5391 9.3843
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 0.9433 1.7154 0.9433 27.3923
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O CTRP2 3.0189 7.5587 1.8622 17.8539
UO-31 CTRP2 3.0389 7.1617 2.0579 17.039
KMRC-3 CTRP2 3.2697 7.2847 2.2396 15.7234
BFTC-909 CTRP2 3.4364 6.2399 2.8632 12.8344
CAL-54 CTRP2 3.6928 8.0087 2.3264 14.3198
TUHR4TKB CTRP2 3.8267 5.9455 3.3943 9.7128
769-P CTRP2 3.897 5.7733 3.081 4.9271
Caki-1 CTRP2 4.6667 11.7903 1.3518 16.0307
ACHN CTRP2 4.9684 8.3777 3.314 7.4211
KMRC-1 CTRP2 5.123 9.0672 3.0981 8.028
VMRC-RCW CTRP2; CTRP1 5.1422 9.1443 3.0852 8.1257
TUHR10TKB CTRP2 5.2565 8.7093 3.3856 13.8922
KMRC-2 CTRP2 5.5905 6.7878 4.5749 1.1349
VMRC-RCZ CTRP2 5.732 10.1614 3.0339 7.2077
A-498 CTRP2 5.7503 7.3966 4.3916 1.6431
SNU-1272 CTRP2 5.8563 12.0379 2.1991 10.4139
OS-RC-2 CTRP2 5.9143 9.4484 3.5185 4.9167
KMRC-20 CTRP2 6.1051 9.0148 3.8583 3.2713
RCC10RGB CTRP2; CTRP1 6.1983 12.0386 2.4671 8.8337
Caki-2 CTRP2 6.4191 17.8546 -0.2542 18.2987
TUHR14TKB CTRP2 8.3454 10.2084 4.4481 0.2447
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW48 CTRP2; CTRP1 0.4322 2.6315 0.4127 30.8587
GP2d CTRP2; CTRP1 0.8442 2.3777 0.8409 28.0626
NCI-H508 CTRP2; CTRP1 0.9673 4.0061 0.8307 27.6949
COLO 320 CTRP2; CTRP1 1.1463 8.3232 -0.3964 31.0633
SNU-81 CTRP2; CTRP1 1.2779 3.3689 1.2427 25.2833
CCK-81 CTRP2 1.5125 3.1636 1.499 23.5751
SNU-175 CTRP1 1.5688 3.6442 1.523 49.8657
SNU-C4 CTRP2; CTRP1 1.5732 3.617 1.5303 23.344
HCT 15 CTRP2 1.6256 2.6695 1.6249 22.7786
LoVo CTRP2; CTRP1 1.6523 4.0026 1.5672 22.9621
NCI-H716 CTRP2 1.6857 4.2169 1.5672 22.7809
LS513 CTRP2; CTRP1 1.7237 3.335 1.7083 22.2495
SNU-1040 CTRP1 1.7682 3.1736 1.7608 47.0349
HT115 CTRP2; CTRP1 1.8312 3.6464 1.7987 21.5918
CL-34 CTRP1 1.881 5.2814 1.5276 46.2709
T84 CTRP2 1.9372 4.1881 1.843 21.0214
DLD-1 CTRP2; CTRP1 1.9393 3.0534 1.9371 20.7706
KM12 CTRP2; CTRP1 1.9404 4.7056 1.7452 21.4299
LS180 CTRP2; CTRP1 2.0994 3.9243 2.0536 19.8519
MDST8 CTRP2; CTRP1 2.1533 4.7942 1.9561 20.0214
HCT 116 CTRP2; CTRP1 2.2293 3.9709 2.1858 18.9797
SNU-407 CTRP2 2.318 4.2346 2.2446 18.413
COLO205 CTRP2; CTRP1 2.4994 4.836 2.3232 17.6456
SW948 CTRP2; CTRP1 2.5079 5.8839 2.0128 18.7553
SNU-61 CTRP2; CTRP1 2.5151 5.5611 2.131 18.2963
RKO CTRP2; CTRP1 2.526 4.4428 2.4352 17.1683
SNU-C2A CTRP2; CTRP1 2.5346 5.8653 2.0483 18.5458
SNU-C5 CTRP2; CTRP1 2.6586 5.8819 2.1761 17.7108
HT-55 CTRP2; CTRP1 2.8443 6.1303 2.2836 16.7774
CW-2 CTRP2; CTRP1 3.0173 6.5895 2.2843 16.2966
CL-40 CTRP1 3.0952 6.3191 2.4765 32.2681
LS1034 CTRP2 3.203 13.2868 -0.6966 26.2507
HCT 8 CTRP2; CTRP1 3.4265 6.024 2.945 12.629
CL-11 CTRP2 3.631 7.1881 2.6479 13.1782
C2BBe1 CTRP2; CTRP1 3.9745 8.8854 2.1808 14.3244
LS123 CTRP2; CTRP1 4.0192 9.3013 2.0192 14.8743
SK-CO-1 CTRP2; CTRP1 4.0306 7.1441 3.0712 10.5666
SNU-C1 CTRP2 4.0564 7.5563 2.8932 11.1478
SNU-503 CTRP2 4.1136 11.4262 1.048 18.3653
LS411N CTRP2; CTRP1 4.1243 6.9775 3.2414 9.6486
NCI-H747 CTRP2 4.3304 8.1856 2.8452 10.7179
SW1463 CTRP2 4.3606 8.9192 2.5113 12.0311
SW480 CTRP1 4.4665 13.7836 0.1936 34.2887
COLO201 CTRP2 4.4773 7.6387 3.2488 8.7179
SNU-1033 CTRP2 4.7802 8.5169 3.0833 8.7659
SW1417 CTRP2 4.9841 9.2247 2.9038 9.1091
OUMS-23 CTRP2 5.4661 6.9802 4.4014 1.9889
SW403 CTRP1 5.5076 10.6029 2.6513 18.6039
HCC-56 CTRP2 5.7252 9.3893 3.4099 5.6618
SW620 CTRP2; CTRP1 5.7613 12.1588 2.076 11.1483
HT-29 CTRP2; CTRP1 5.8473 11.2818 2.5775 8.9676
RCM-1 [Human ESC] CTRP2; CTRP1 5.8597 10.4274 3.0093 7.174
COLO 678 CTRP2; CTRP1 8.3503 16.5529 1.7688 8.4258
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLF CTRP2 1.5106 3.975 1.4185 23.8555
SNU-398 CTRP2; CTRP1 1.8728 6.709 1.0244 24.232
SNU-182 CTRP2 2.0118 5.5081 1.5975 21.6676
JHH-2 CTRP2 2.5833 5.8572 2.0996 18.1354
SNU-423 CTRP2 2.647 5.7117 2.2196 17.5031
JHH-4 CTRP2 2.6533 5.1808 2.3964 16.8332
SNU-886 CTRP2 3.1328 11.0641 0.3234 23.2401
Li-7 CTRP2 3.1678 14.7562 -1.4522 28.3612
HuH-6 CTRP2 3.3234 6.0139 2.8346 13.2549
JHH-5 CTRP2 3.3466 6.8005 2.532 14.37
JHH-1 CTRP2 3.4403 7.0724 2.5078 14.2218
PLC/PRF/5 CTRP2 3.5333 6.5689 2.8248 12.7259
SK-HEP-1 CTRP2 4.5729 9.4568 2.4339 11.8966
SNU-878 CTRP2 4.667 6.979 3.747 6.2284
SNU-449 CTRP2; CTRP1 5.083 12.2268 1.495 14.709
SNU-475 CTRP2 5.4089 9.938 2.8943 8.3505
Hep-G2 CTRP2; CTRP1 5.7812 9.64 3.3389 5.9422
Hep 3B2.1-7 CTRP2 5.9094 9.5935 3.4443 5.2279
JHH-6 CTRP2; CTRP1 5.9147 10.3709 3.0779 6.8015
SNU-387 CTRP2 6.0232 14.195 1.257 13.7939
HuH-1 CTRP2 8.4808 63.3293 -21.2861 39.2911
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 151 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1876 CTRP1 -1.6747 8.1425 -3.3136 66.6
NCI-H1836 CTRP1 -0.8243 4.6952 -1.2661 69.563
NCI-H2141 CTRP1 -0.4352 24.5672 -9.582 54.336
NCI-H1341 CTRP2 -0.2268 2.1418 -0.2429 35.1704
NCI-H1155 CTRP2 -0.1573 0.9068 -0.1573 34.6544
SCLC-21H CTRP1 -0.1243 0.8821 -0.1243 73.9227
NCI-H211 CTRP2 -0.0959 1.2886 -0.0962 34.2465
NCI-H1694 CTRP2; CTRP1 0.1334 5.9489 -0.5834 34.9453
NCI-H1963 CTRP1 0.1392 1.8284 0.1367 69.5894
NCI-H1048 CTRP1 0.1693 2.7547 0.1329 67.5224
SBC-5 CTRP2 0.256 1.2816 0.2559 31.9013
COR-L279 CTRP1 0.4186 1.9459 0.4168 65.971
NCI-H1581 CTRP2 0.5419 2.8656 0.5124 30.0951
NCI-H526 CTRP2 0.6144 1.2872 0.6144 29.5133
NCI-H82 CTRP1 0.6861 1.8149 0.6859 62.4211
NCI-H1930 CTRP1 0.715 18.5293 -5.5679 52.5596
LC-1F CTRP2 0.8616 3.388 0.8026 28.0648
NCI-H446 CTRP2 0.932 2.4979 0.9276 27.4119
NCI-H23 CTRP2; CTRP1 0.9407 2.2453 0.9395 27.4133
DMS 273 CTRP2; CTRP1 0.982 3.7348 0.8888 27.4489
SHP-77 CTRP2; CTRP1 1.004 1.9764 1.0039 26.9886
HCC1438 CTRP2 1.0355 2.5004 1.0323 26.7186
NCI-H2029 CTRP2; CTRP1 1.1674 5.6424 0.6395 27.7138
NCI-H841 CTRP2; CTRP1 1.2243 4.0762 1.0956 25.9592
Lu-99 CTRP2; CTRP1 1.2408 3.2496 1.2131 25.5051
HCC1359 CTRP1 1.2522 2.9697 1.2403 54.28
DMS 53 CTRP2 1.3373 3.7146 1.2691 24.9277
NCI-H1703 CTRP2 1.3533 2.1683 1.3532 24.5911
NCI-H522 CTRP2; CTRP1 1.4023 3.5913 1.3528 24.5041
NCI-H596 CTRP1 1.4952 2.4164 1.495 50.9094
HCC33 CTRP1 1.5118 3.147 1.4992 50.6577
DMS 454 CTRP2 1.5211 5.2737 1.1343 24.8202
NCI-H1781 CTRP1 1.568 3.4047 1.5427 49.8733
Calu-6 CTRP2; CTRP1 1.579 6.0252 0.9594 25.3353
VMRC-LCD CTRP2; CTRP1 1.5835 2.7599 1.5819 23.1367
DMS 114 CTRP2 1.6313 3.5482 1.597 22.8539
NCI-H2286 CTRP2; CTRP1 1.6404 5.1343 1.3073 23.9119
RERF-LC-A1 CTRP2 1.6773 2.7938 1.676 22.4365
LK2 CTRP2 1.6821 2.0554 1.6821 22.4002
NCI-H810 CTRP2; CTRP1 1.6874 6.0336 1.0738 24.6029
NCI-H1385 CTRP2 1.7268 8.9717 -0.0829 28.3231
NCI-H1184 CTRP2 1.7324 4.1844 1.6231 22.4377
NCI-H1092 CTRP2 1.7508 7.3771 0.6243 25.9295
NCI-H889 CTRP2 1.9024 4.1846 1.8061 21.2606
HCC1588 CTRP2 1.9541 3.7245 1.9201 20.7023
MOR/CPR CTRP2 1.9994 3.9969 1.9377 20.4953
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 2.0184 3.3437 2.0106 20.2625
NCI-H520 CTRP2 2.0441 4.1207 1.9682 20.2464
COLO 699 CTRP2; CTRP1 2.0713 5.2892 1.7328 21.0734
COLO 668 CTRP2; CTRP1 2.0793 6.2935 1.4027 22.2563
NCI-H1734 CTRP2 2.1171 5.7266 1.6405 21.1974
COR-L23 CTRP1 2.1586 5.7915 1.6672 43.3022
NCI-H1693 CTRP2 2.1887 5.4941 1.7944 20.4209
COR-L51 CTRP2; CTRP1 2.1895 5.1504 1.902 20.1046
NCI-H661 CTRP2; CTRP1 2.2434 6.4628 1.5145 21.3714
NCI-H1568 CTRP2; CTRP1 2.2476 6.137 1.6411 20.8898
ChaGo-K-1 CTRP2; CTRP1 2.2613 7.1258 1.2693 22.2292
HCC95 CTRP2 2.3352 6.1373 1.731 20.2268
RERF-LC-MS CTRP2 2.4496 5.207 2.1666 18.2825
NCI-H1975 CTRP1 2.47 5.0448 2.2374 38.3417
NCI-H1105 CTRP2; CTRP1 2.4901 8.5015 0.9094 22.9162
HCC44 CTRP2; CTRP1 2.5286 4.6645 2.3943 17.3031
LCLC-97TM1 CTRP2; CTRP1 2.5368 5.1496 2.2812 17.6821
COR-L95 CTRP2 2.6993 6.6903 1.9034 18.5514
SK-MES-1 CTRP2 2.7552 6.8893 1.8798 18.4888
NCI-H1299 CTRP2; CTRP1 2.7636 5.6091 2.3847 16.6293
DV-90 CTRP2; CTRP1 2.7697 5.5493 2.4114 16.5121
NCI-H838 CTRP2 2.8081 5.4631 2.4779 16.073
NCI-H650 CTRP2; CTRP1 2.838 23.9187 -6.2803 37.1555
NCI-H2081 CTRP2; CTRP1 2.8854 5.9562 2.3931 16.247
NCI-H69 CTRP2 2.888 5.4047 2.5836 15.4472
NCI-H1755 CTRP2; CTRP1 2.9125 6.6556 2.1469 17.1113
NCI-H2073 CTRP1 2.9969 5.3289 2.7294 31.3437
NCI-H1339 CTRP2 3.0022 5.8969 2.5361 15.294
NCI-H2087 CTRP2 3.0945 7.1512 2.1195 16.6518
HCC4006 CTRP2; CTRP1 3.1187 6.2816 2.5163 15.1251
COR-L88 CTRP2; CTRP1 3.2554 7.9466 1.9312 17.0539
NCI-H2009 CTRP2; CTRP1 3.2806 6.9512 2.4042 15.1265
LXF 289 CTRP2; CTRP1 3.296 5.9853 2.8213 13.4651
NCI-H1373 CTRP2; CTRP1 3.3938 7.0507 2.4764 14.5471
HCC366 CTRP2 3.424 5.829 3.0134 12.2904
Lu-65 CTRP2; CTRP1 3.4322 6.4135 2.7919 13.2059
LCLC-103H CTRP2; CTRP1 3.4995 5.4761 3.2273 11.3531
NCI-H1437 CTRP1 3.5068 6.7099 2.7421 27.8506
HCC2108 CTRP2; CTRP1 3.546 6.9979 2.6547 13.4485
NCI-H358 CTRP2; CTRP1 3.5593 7.16 2.5952 13.6515
LOU-NH91 CTRP2 3.6147 6.8704 2.7753 12.7107
NCI-H2122 CTRP2; CTRP1 3.6173 5.9796 3.1649 11.2574
NCI-H322 CTRP2 3.6467 6.7288 2.8711 12.2473
HCC2279 CTRP2 3.6581 5.5914 3.3534 10.338
CAL-12T CTRP2; CTRP1 3.7202 6.6891 2.9698 11.7492
LUDLU-1 CTRP2 3.7641 6.7671 2.9731 11.5401
HCC15 CTRP2; CTRP1 3.7729 7.3493 2.7216 12.6108
HCC1833 CTRP2; CTRP1 3.7813 7.861 2.4896 13.5272
HCC78 CTRP2; CTRP1 3.8727 7.0989 2.9367 11.4972
KNS-62 CTRP2; CTRP1 3.8902 6.3159 3.3083 9.9671
NCI-H1944 CTRP2; CTRP1 3.901 8.0605 2.5101 13.159
Calu-3 CTRP2; CTRP1 3.9395 7.2622 2.9265 11.3749
HCC827 CTRP2; CTRP1 3.9482 6.5248 3.2749 9.9501
NCI-H2342 CTRP2; CTRP1 4.0159 8.603 2.357 13.5143
A-549 CTRP2; CTRP1 4.0242 5.9199 3.6172 8.3991
NCI-H1838 CTRP2 4.0253 7.1044 3.0776 10.4699
RERF-LC-KJ CTRP1 4.102 7.383 3.0274 22.3269
NCI-H460 CTRP2; CTRP1 4.1182 6.0822 3.6448 8.0423
NCI-H1435 CTRP2; CTRP1 4.1265 8.1267 2.6923 11.8896
EBC-1 CTRP2; CTRP1 4.1871 8.0249 2.7988 11.3139
NCI-H292 CTRP2 4.2048 6.805 3.3941 8.7476
NCI-H1650 CTRP2 4.2308 7.7052 2.9872 10.3556
NCI-H727 CTRP2; CTRP1 4.2485 7.3326 3.1919 9.5562
NCI-H647 CTRP2 4.2675 9.2198 2.2784 13.1911
NCI-H2405 CTRP2; CTRP1 4.2847 10.83 1.5052 16.3208
NCI-H1915 CTRP2; CTRP1 4.2853 8.7397 2.5398 12.1588
NCI-H1793 CTRP2; CTRP1 4.3334 7.1261 3.3723 8.6174
NCI-H1355 CTRP2; CTRP1 4.4911 8.275 2.9562 9.9868
NCI-H1792 CTRP2; CTRP1 4.5297 6.7783 3.7263 6.7076
LC-1/sq-SF CTRP2; CTRP1 4.5476 6.033 4.1 5.1346
HCC2935 CTRP2; CTRP1 4.6547 9.361 2.5623 11.2748
EPLC-272H CTRP2; CTRP1 4.6632 10.6741 1.9151 13.8985
NCI-H2030 CTRP2; CTRP1 4.6639 7.0736 3.706 6.4917
NCI-H2196 CTRP2 4.7301 11.1608 1.7205 14.4619
NCI-H1666 CTRP2; CTRP1 4.8167 9.2112 2.7776 10.049
NCI-H1869 CTRP2 5.0267 11.8609 1.6214 14.2557
Sq-1 CTRP2; CTRP1 5.0349 7.2658 3.9354 4.764
NCI-H2170 CTRP2 5.0503 6.284 4.4295 2.5732
T3M-10 CTRP2; CTRP1 5.1403 10.2505 2.5306 10.4378
NCI-H2126 CTRP2; CTRP1 5.202 8.5533 3.4294 6.5711
Calu-1 CTRP2 5.21 9.7831 2.8116 9.0612
HOP-62 CTRP2 5.2345 11.08 2.1835 11.6048
BEN CTRP2; CTRP1 5.3205 7.0435 4.2753 2.8193
NCI-H2085 CTRP2 5.3721 9.6647 3.0014 7.9705
NCI-H2291 CTRP2 5.3741 9.2337 3.2177 7.063
NCI-H2023 CTRP2; CTRP1 5.434 8.1987 3.7896 4.6492
NCI-H2110 CTRP2; CTRP1 5.448 10.446 2.6824 9.2369
NCI-H441 CTRP2; CTRP1 5.5093 10.1959 2.8554 8.4103
NCI-H2172 CTRP2; CTRP1 5.5321 7.7767 4.0713 3.3187
HCC1171 CTRP2 5.6732 9.4429 3.3447 6.0177
HCC1195 CTRP2; CTRP1 5.6756 10.0061 3.0786 7.1953
COR-L105 CTRP2 5.6947 9.5051 3.3301 6.0426
NCI-H1395 CTRP2 5.7157 8.9693 3.6095 4.8526
SK-LU-1 CTRP2; CTRP1 5.7311 9.8076 3.2188 6.5214
NCI-H196 CTRP2 5.8101 8.5884 3.8628 3.6691
IA-LM CTRP2 5.9299 9.2081 3.6464 4.3709
EKVX CTRP2 5.9468 14.6947 0.9491 15.0662
RERF-LC-Ad2 CTRP2 6.2185 11.5512 2.71 7.7444
RERF-LC-Ad1 CTRP2 6.2463 7.0491 4.7844 0.0891
NCI-H1573 CTRP2; CTRP1 6.3633 11.2117 2.9901 6.4625
NCI-H3255 CTRP1 6.7577 11.8035 2.9757 12.0655
HOP-92 CTRP2 6.9073 29.5525 -5.6939 29.4625
NCI-H1623 CTRP2 7.9322 20.0284 -0.1986 15.6565
NCI-H1563 CTRP2 8.7723 18.6305 1.0503 10.3538
Hs 888.Lu CTRP2 5.0607 9.4813 2.8395 9.2288
⏷ Show the Full List of 151 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 0.6981 1.3639 0.6981 28.9557
SYO-1 CTRP2 2.5575 4.6017 2.4372 16.9815
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.279 9.2404 0.3548 25.3538
OVKATE CTRP1 0.5971 1.9372 0.5963 63.6104
OC 314 CTRP2 0.6129 1.6511 0.6128 29.5236
A2780 CTRP2; CTRP1 0.9393 3.0019 0.9163 27.4957
TOV-112D CTRP2 0.9572 2.2557 0.9561 27.2332
COV434 CTRP2; CTRP1 1.4653 5.4738 1.0164 25.4805
ONCO-DG-1 CTRP2 1.5041 2.9313 1.4986 23.6044
RMUG-S CTRP1 1.6482 7.4667 0.4848 49.2615
JHOS-4 CTRP1 1.7465 6.2151 1.0733 48.1318
OAW42 CTRP2; CTRP1 1.8829 5.9029 1.3305 23.0964
ES2 CTRP2 1.904 3.1185 1.9002 20.9345
OVK18 CTRP2; CTRP1 1.9077 4.4397 1.7671 21.4553
OVCAR-8 CTRP2; CTRP1 1.9172 3.3716 1.9058 20.9484
MCAS CTRP2 2.6219 4.948 2.4264 16.8201
RMG-I CTRP2; CTRP1 2.8565 6.7745 2.039 17.6792
IGROV-1 CTRP2; CTRP1 3.0166 5.7715 2.6016 15.0876
TYK-nu CTRP2; CTRP1 3.0945 6.2876 2.4883 15.2994
DOV13 CTRP2 3.0953 6.2825 2.0832 11.2753
Caov-3 CTRP2; CTRP1 3.2913 6.8545 2.4573 14.8898
HEY A8 CTRP2; CTRP1 3.4037 7.3736 2.3415 15.0562
JHOM-1 CTRP2; CTRP1 3.5727 7.4234 2.4884 14.0444
OVCAR-4 CTRP2; CTRP1 3.6033 6.1582 3.0774 11.6343
OV-90 CTRP2; CTRP1 3.6067 6.5333 2.9218 12.2342
OV7 CTRP2; CTRP1 3.8489 7.6369 2.6614 12.6686
SNU-8 CTRP2 3.8789 6.0332 3.4125 9.5014
OV56 CTRP2 4.1164 7.6091 2.9253 10.875
COV644 CTRP2; CTRP1 4.1165 7.7008 2.8889 11.1067
SNU-119 CTRP2 4.251 10.1373 1.8099 15.1205
EFO-21 CTRP2; CTRP1 4.2721 6.8554 3.443 8.4724
JHOC-5 CTRP2; CTRP1 4.3634 7.9568 2.9962 10.1016
OVISE CTRP2 4.5952 7.1798 2.9414 4.1887
SK-OV-3 CTRP2; CTRP1 4.6396 8.9297 2.7639 10.4704
OAW28 CTRP2 4.672 10.7678 1.8667 13.9994
SNU-840 CTRP2; CTRP1 4.964 7.4749 3.7709 5.5945
OVTOKO CTRP2 5.0337 9.4569 2.8293 9.3238
EFO-27 CTRP2; CTRP1 5.2668 9.3627 3.0777 7.9235
OVCAR-5 CTRP2 5.6779 11.6418 2.2576 10.4901
OVMANA CTRP1 6.0688 10.98 2.892 14.8517
COV362 CTRP2; CTRP1 6.2993 24.0208 -3.4092 26.5315
Kuramochi CTRP2 6.4202 11.7505 2.7572 7.2422
JHOS-2 CTRP2 6.7631 13.4568 2.1702 9.0566
FU-OV-1 CTRP2 7.0433 8.8582 4.436 0.4687
COV318 CTRP1 7.0938 10.7663 3.6697 6.0828
OVSAHO CTRP2 7.3842 16.4791 1.1402 11.9934
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 3.935 10.0983 1.5423 16.8805
Yamato-SS CTRP2 6.3758 14.1295 1.5581 12.0485
G-401 CTRP2; CTRP1 0.5306 3.9215 0.3747 30.6595
Rh41 CTRP2 1.2643 3.3387 1.2304 25.2974
KYM-1 CTRP2 1.2666 3.9067 1.1672 25.5055
RKN CTRP2; CTRP1 1.7246 2.6367 1.7243 22.193
HT-1080 CTRP2; CTRP1 1.8875 4.8255 1.6587 21.9007
BT-12 CTRP2 1.8986 2.4859 1.8986 20.9576
A-204 CTRP2 1.9011 6.1917 1.2442 23.2828
GCT CTRP2 2.0448 4.0446 1.9798 20.204
SK-UT-1 CTRP2 2.0527 5.43 1.6665 21.2941
TE 617.T CTRP2 2.2557 4.4827 2.1339 18.9965
TE 441.T CTRP2 2.3068 5.915 1.7807 20.1243
RD CTRP2 2.3353 5.2502 2.0292 19.126
TTC-709 CTRP2 2.5049 4.9434 2.2999 17.6326
G-402 CTRP2 2.6191 6.8633 1.748 19.3649
SW982 CTRP2 2.7339 4.1247 2.7018 15.5013
BT-16 CTRP2 2.8051 5.2136 2.5524 15.8087
MES-SA CTRP2 2.8926 6.759 2.078 17.3526
Tm87-16 CTRP2 3.5968 9.084 1.72 16.9711
SK-LMS-1 CTRP2 3.7562 7.4457 2.6533 12.8456
Hs 729.T CTRP2 4.8147 8.6002 3.0716 8.7443
Rh18 CTRP2 5.0318 9.7031 2.7046 9.847
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.4055 7.9502 4.5082 1.3555
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2; CTRP1 -2.0664 3.4921 -2.3522 47.6762
NCI-H28 CTRP2; CTRP1 2.5167 4.6026 2.3945 17.3399
MPP 89 CTRP2 2.8797 5.6109 2.5062 15.7587
IST-Mes1 CTRP2 3.2522 13.3005 -0.6582 26.022
NCI-H2052 CTRP2; CTRP1 5.4627 9.8678 2.9821 7.9668
ACC-MESO-1 CTRP2 5.5838 7.2921 4.3321 2.099
JL-1 CTRP2 5.8768 9.9085 3.2664 6.0101
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 CTRP2 1.9261 5.7028 1.1522 18.4285
LNCaP clone FGC CTRP2 3.6692 6.4471 3.0178 11.6077
VCaP CTRP2 4.3775 9.6225 2.1783 13.3603
DU145 CTRP2 4.6142 9.7847 2.3068 12.3332
PaCa-3 CTRP2; CTRP1 4.752 9.724 2.4659 11.4729
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 1.8029 3.0859 1.7984 21.6104
A-253 CTRP2 3.6986 7.4421 2.5981 13.2099
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCC-StC-K140 CTRP2 0.4104 5.4116 -0.1177 32.5755
SNU-16 CTRP2 0.9488 2.0056 0.9486 27.286
ECC10 CTRP2 1.5833 5.2463 1.2102 24.3596
GSS CTRP2 1.6338 2.2761 1.6338 22.7216
SNU-5 CTRP2 1.8026 2.5335 1.8026 21.5974
23132/87 CTRP2 1.9038 3.0689 1.9009 20.9328
ECC12 CTRP2 1.9164 2.7308 1.9163 20.8394
SNU-620 CTRP2 2.1253 3.0237 2.1246 19.4496
HGC-27 CTRP2 2.2037 6.3429 1.5132 21.4151
HuG1-N CTRP2 2.3541 9.0435 0.52 24.5875
IM95 CTRP2 2.9527 5.4046 2.654 14.9966
LMSU CTRP2 3.2422 6.9256 2.3699 15.2818
NUGC-4 CTRP2; CTRP1 3.2567 6.0263 2.7637 13.7947
NUGC-3 CTRP2 3.2577 6.2036 2.6897 13.9936
NCI-N87 CTRP2 3.269 7.9695 1.9274 16.957
SNU-216 CTRP2 3.3702 6.8913 2.5165 14.369
SNU-1 CTRP2 3.4403 10.279 0.994 20.1196
OCUM-1 CTRP2 3.8512 8.2926 2.3435 13.8728
SNU-601 CTRP2 4.0392 7.0826 3.1015 10.339
AGS CTRP2; CTRP1 4.1361 6.7643 3.3529 9.1671
MKN74 CTRP2; CTRP1 4.2572 9.5927 2.0935 14.0436
Hs 746.T CTRP2 4.4475 8.6504 2.7227 10.9689
Fu97 CTRP2; CTRP1 4.5353 8.9866 2.6433 11.1902
SH-10-TC CTRP2; CTRP1 4.5722 6.626 3.8403 6.1401
SNU-719 CTRP2 4.7301 8.388 3.104 8.7821
GSU CTRP2 5.2559 8.356 3.5614 5.8372
MKN1 CTRP2 5.3726 8.3428 3.6601 6.0331
KE-39 CTRP2 5.4838 10.7043 2.5718 9.552
MKN7 CTRP2; CTRP1 5.7031 10.5936 2.8084 8.2662
KATO III CTRP2 5.705 12.6597 1.7723 12.3819
MKN45 CTRP2 5.7648 7.2924 4.449 1.4064
SNU-668 CTRP2 6.6473 10.1829 3.6564 3.3689
SNG-M CTRP2; CTRP1 2.2627 4.034 2.214 18.775
SNU-685 CTRP2 3.7104 6.9744 2.8251 12.2682
SNU-1077 CTRP2 4.7242 9.3409 2.6238 10.7972
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-238 CTRP2 0.1421 5.0477 -0.3065 34.0693
B-CPAP CTRP2 1.6923 3.4014 1.6717 22.4012
8305C CTRP2 2.2727 4.1011 2.2152 18.6601
SW579 CTRP2 2.4692 4.8465 2.2854 17.7944
8505C CTRP2 2.5958 6.6602 1.8064 19.2073
CAL-62 CTRP2 2.7689 5.085 2.5499 15.9271
TT CTRP2 3.7299 5.5203 3.4566 9.7438
BHT-101 CTRP2 3.9729 6.1039 3.4799 8.9873
FTC-133 CTRP2 4.168 10.7709 1.4215 16.8281
CGTH-W-1 CTRP2 4.3911 7.8068 3.0871 9.5805
TT2609-C02 CTRP2 5.4033 10.1276 2.7954 8.7718
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-27 CTRP2 -3.4567 8.705 -5.4385 53.9094
PE/CA-PJ34 (clone C12) CTRP2 0.9397 3.3508 0.8888 27.5174
PE/CA-PJ49 CTRP2 0.9456 2.6061 0.9389 27.3291
HSC-2 CTRP2; CTRP1 1.093 2.8827 1.0805 26.4375
CAL-33 CTRP2 1.2112 2.7595 1.2051 25.5577
YD-10B CTRP2 1.5853 2.4112 1.5853 23.045
SCC-4 CTRP2 1.7532 4.1143 1.6572 22.2533
PE/CA-PJ15 CTRP2 1.8274 5.3781 1.4371 22.8031
HSC-3 CTRP2 1.8491 4.4867 1.6921 21.8272
SNU-1214 CTRP2 2.5305 5.1649 2.267 17.6736
BICR 22 CTRP2 2.9183 5.9498 2.4264 15.9471
Detroit 562 CTRP2 3.0044 6.5192 2.2944 16.2129
SCC-9 CTRP2; CTRP1 3.0115 6.3985 2.356 16.036
BICR 6 CTRP2 3.5413 5.5747 3.2337 11.1232
SNU-1076 CTRP2 3.8672 6.4175 3.2341 10.2354
BICR 18 CTRP2 3.963 8.5413 2.3293 13.6695
SCC-25 CTRP2 4.1337 8.3453 2.5847 12.234
BICR 16 CTRP2 4.2513 6.67 3.5032 8.1909
BICR 56 CTRP2 4.2583 13.7267 0.032 21.5981
YD-8 CTRP2 4.2841 7.7712 3.0051 10.1606
BHY CTRP2 4.7706 9.0764 2.7959 9.9862
PE/CA-PJ41 (clone D2) CTRP2 4.8212 12.8475 0.9553 17.2025
FaDu CTRP2 4.9769 9.3141 2.8531 9.3352
BICR 31 CTRP2 5.062 13.547 0.8078 17.2541
SNU-899 CTRP2 5.2604 7.6112 3.9363 4.2572
HSC-4 CTRP2 5.45 9.3219 3.2336 6.862
SNU-1066 CTRP2 6.042 8.6381 3.9954 2.8146
SNU-1041 CTRP2 6.2156 9.998 3.4626 4.6981
SNU-46 CTRP2 7.6524 15.4082 1.8418 9.0227
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
647V CTRP2 -0.2557 8.9454 -2.1289 39.6234
SCaBER CTRP2 0.6172 6.096 -0.1104 31.8577
5637 CTRP2; CTRP1 1.2496 2.6823 1.2458 25.3663
JMSU-1 CTRP2 1.8905 3.6505 1.8598 21.1149
VM-CUB-1 CTRP2 2.2161 4.1698 2.1451 19.0837
UM-UC-3 CTRP2; CTRP1 2.2267 4.9157 2.006 19.6173
RT-112 CTRP2 2.726 3.7899 2.718 15.472
639V CTRP2 2.9001 5.5054 2.5639 15.4847
RT-4 CTRP2; CTRP1 3.3109 5.6905 2.948 12.9425
U-BLC1 CTRP2 3.4345 8.115 2.0236 16.1634
253J CTRP2 3.4818 5.7183 3.1171 11.7333
T24 CTRP2 3.5732 7.667 2.3695 14.4389
SW1710 CTRP2 3.6141 6.4723 2.9501 12.0199
253J-BV CTRP2 3.7068 5.741 3.3492 10.2169
BFTC-905 CTRP2 4.0837 6.8052 3.2752 9.5251
BC-3C CTRP2 4.2618 7.5112 3.1105 9.7764
CAL-29 CTRP2 4.2674 6.7373 3.4872 8.2177
UM-UC-1 CTRP2 4.5745 9.4682 2.4296 11.9112
HT-1376 CTRP2; CTRP1 4.6102 7.9202 3.239 8.553
TCCSUP CTRP2 4.8967 8.3519 3.266 7.7646
KU-19-19 CTRP2 4.9935 9.0574 2.9954 8.7076
HT-1197 CTRP2 5.6155 10.1882 2.9316 7.8301
J82 CTRP2 6.2422 11.7327 2.6383 7.9976
KMBC-2 CTRP2; CTRP1 8.9293 17.5081 1.688 7.9969
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 2.6837 4.7634 2.5391 16.2272

References

1 Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors. J Med Chem. 2008 Dec 11;51(23):7327-43.