Details of the Drug

General Information of Drug (ID: DM90BUD)

Drug Name

ChronSeal

Synonyms

Antibiotic-free recombinant HGF, Linkoping; Recombinant HGF, Kringle/ChronTech; Recombinant HGF, Kringle/Tripep

Indication

Disease Entry	ICD 11	Status	REF
Fibrosis	GA14-GC01	Phase 1/2	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Fibrosis

ICD Disease Classification

GA14-GC01

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Proto-oncogene c-Met (MET)	DTT	MET	1.08E-03	-0.24	-0.4

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT00797706) Phase I/II Dose Ranging CHRONSEAL Study in Venous Leg Ulcers. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Kringle Pharma.