Details of the Drug

General Information of Drug (ID: DM94KQP)

Drug Name
Aminopyridine deriv. 2
Synonyms
JNK Inhibitor VIII; TCS JNK 6o; 894804-07-0; aminopyridine deriv. 2; N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide; Kinome_3020; SCHEMBL157014; GTPL5998; CHEMBL210618; BDBM15908; Aminopyridine-Based Inhibitor 6o; CTK8E8164; DTXSID20469650; MolPort-023-276-703; HMS3229K06; IN1283; ZINC14959960; AKOS024457488; CCG-206859; NCGC00387087-01; RT-013406; B7321
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 356.4
Logarithm of the Partition Coefficient (xlogp) 2.2
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C18H20N4O4
IUPAC Name
N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide
Canonical SMILES
CCOC1=C(C(=CC(=N1)NC(=O)CC2=C(C=CC(=C2)OC)OC)N)C#N
InChI
InChI=1S/C18H20N4O4/c1-4-26-18-13(10-19)14(20)9-16(22-18)21-17(23)8-11-7-12(24-2)5-6-15(11)25-3/h5-7,9H,4,8H2,1-3H3,(H3,20,21,22,23)
InChIKey
KQMPRSZTUSSXND-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11624601
CAS Number
894804-07-0
TTD ID
D00HVA

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
JNK2 messenger RNA (JNK2 mRNA) TT3IVG2 MK09_HUMAN Inhibitor [1]
Stress-activated protein kinase JNK1 (JNK1) TT0K6EO MK08_HUMAN Inhibitor [1]
Stress-activated protein kinase JNK3 (JNK3) TT056SO MK10_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Stress-activated protein kinase JNK1 (JNK1) DTT MAPK8 1.48E-07 1.2 2.27
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 6.1561 8.3387 2.6051 0.5589
EW-24 GDSC1; GDSC2 4.0471 6.6901 2.1972 5.267
HOS GDSC1; GDSC2 4.2468 6.4662 2.4375 3.4126
CHSA8926 GDSC1; GDSC2 4.3896 7.1876 2.19 4.5898
EW-1 GDSC1; GDSC2 4.4335 11.6149 0.0614 16.5406
ES1 GDSC1; GDSC2 4.653 7.3676 2.2713 3.6316
MG-63 GDSC1; GDSC2 4.8643 8.5733 1.8434 5.6936
ES8 GDSC1; GDSC2 4.9498 8.0002 2.1598 3.754
EW-22 GDSC1; GDSC2 4.9644 7.2237 2.5101 1.9022
TC-71 GDSC1; GDSC2 4.9688 6.5911 2.7715 0.7564
U2OS GDSC1; GDSC2 4.9942 8.5897 1.9169 5.0346
G-292 clone A141B1 GDSC1; GDSC2 5.0025 7.125 2.5711 1.568
HuO-3N1 GDSC1; GDSC2 5.0037 7.5559 2.3877 2.4605
EW-13 GDSC1; GDSC2 5.0374 7.5699 2.3998 2.3538
MHH-ES-1 GDSC1; GDSC2 5.0772 7.9455 2.2571 3.0328
CHSA0108 GDSC1; GDSC2 5.2336 7.5582 2.5051 1.6136
A-673 GDSC1; GDSC2 5.3799 6.7636 2.8735 0.2362
CHSA0011 GDSC1; GDSC2 5.3964 8.9346 1.9978 3.9263
CAL-72 GDSC1; GDSC2 5.431 7.4367 2.645 0.8665
ES7 GDSC1; GDSC2 5.5034 7.6849 2.5801 1.0497
SJSA-1 GDSC1; GDSC2 5.5441 7.1732 2.7897 0.3626
H-EMC-SS GDSC1; GDSC2 5.5736 13.211 0.1049 13.6554
EW-12 GDSC2 5.5877 7.4625 2.701 0.5815
CADO-ES1 GDSC1; GDSC2 5.645 7.409 2.7435 0.4342
ES4 GDSC1; GDSC2 5.6852 8.597 2.2964 2.0649
SK-PN-DW GDSC1; GDSC2 5.8048 11.2658 1.1791 7.6539
NY GDSC1; GDSC2 5.8324 12.0774 0.8178 9.5172
EW-16 GDSC1; GDSC2 5.8443 8.3112 2.4859 1.1324
SK-ES-1 GDSC1; GDSC2 5.9768 7.7695 2.7408 0.3103
EW-7 GDSC1; GDSC2 5.9854 7.5885 2.8068 0.1878
NOS-1 [Human HNSCC] GDSC1; GDSC2 6.0176 8.1254 2.6286 0.5627
EW-18 GDSC1; GDSC2 6.0388 7.8085 2.7499 0.2725
U-CH2 GDSC2 6.1129 7.9435 2.73 0.2883
ES5 GDSC1; GDSC2 6.1143 9.3108 2.2106 1.9959
HuO9 GDSC1; GDSC2 6.1397 8.122 2.6769 0.39
EW-11 GDSC1; GDSC2 6.1522 8.4749 2.5535 0.7053
EW-3 GDSC1; GDSC2 6.2054 8.1966 2.6752 0.3698
SaOS-2 GDSC1; GDSC2 6.2906 8.0252 2.7656 0.1823
CAL-78 GDSC1; GDSC2 6.3887 15.0382 -0.2197 13.5021
ES6 GDSC1; GDSC2 6.3901 8.3465 2.6907 0.2803
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 4.8519 7.6231 2.2729 3.2926
SU-DHL-1 GDSC2 -5.2241 36.4286 -20.7998 54.6591
SIG-M5 GDSC2 3.436 7.0993 1.5275 10.9943
DEL GDSC1; GDSC2 3.6505 7.9976 1.2519 12.0729
MC116 GDSC1; GDSC2 3.7256 5.1542 2.7165 2.8068
Hs 445 GDSC2 3.897 5.8192 2.514 3.6655
KMS-12-BM GDSC2 3.9139 6.001 2.4379 4.0923
NB4 GDSC1; GDSC2 3.9524 5.6208 2.6458 2.7572
HL-60 GDSC1; GDSC2 4.002 6.1952 2.405 4.1007
OPM-2 GDSC1; GDSC2 4.1069 5.4653 2.8122 1.5357
HT GDSC1; GDSC2 4.1133 5.7872 2.6698 2.3163
HEL GDSC1; GDSC2 4.1428 6.2686 2.4637 3.4592
L-428 GDSC1; GDSC2 4.1469 5.9336 2.6228 2.5245
MOLT-16 GDSC1; GDSC2 4.1605 6.804 2.2205 4.8782
SCC-3 GDSC2 4.173 5.9936 2.6111 2.5448
OCI-Ly7 GDSC1; GDSC2 4.2394 5.5716 2.8383 1.2108
TALL-1 [Human adult T-ALL] GDSC2 4.2604 9.4398 1.0055 11.9229
MLMA GDSC1; GDSC2 4.273 6.9646 2.2192 4.6508
RPMI-6666 GDSC1; GDSC2 4.2827 5.7169 2.7986 1.3532
JURL-MK1 GDSC1; GDSC2 4.2902 5.8345 2.7513 1.5863
KOPN-8 GDSC1; GDSC2 4.2903 6.0426 2.6588 2.0805
BC-1 GDSC1; GDSC2 4.3089 6.7466 2.3457 3.8312
MV4-11 GDSC1; GDSC2 4.3093 6.0113 2.6837 1.9159
BALL-1 GDSC1; GDSC2 4.3151 6.5904 2.4226 3.3712
P32/ISH GDSC1; GDSC2 4.3588 5.5128 2.9227 0.6852
RS4;11 GDSC1; GDSC2 4.3719 6.3334 2.5751 2.4082
Ramos.2G6.4C10 GDSC1; GDSC2 4.4052 6.0535 2.7183 1.595
LAMA-84 GDSC1; GDSC2 4.4072 6.7057 2.4262 3.184
SU-DHL-5 GDSC1; GDSC2 4.4124 5.671 2.8837 0.7984
DB GDSC1; GDSC2 4.4214 6.7432 2.4176 3.2078
NCI-H929 GDSC1; GDSC2 4.4242 6.8373 2.3758 3.4414
BL-41 GDSC1; GDSC2 4.4283 5.82 2.83 1.0214
RL GDSC1; GDSC2 4.4976 6.6601 2.501 2.6125
NK-92MI GDSC2 4.503 7.7775 1.9848 5.5765
CMK GDSC1 4.5125 6.5669 2.5514 2.8835
MOLM-16 GDSC1; GDSC2 4.5387 6.9964 2.3724 3.2593
YT GDSC1; GDSC2 4.5687 6.2719 2.7107 1.4195
SR GDSC1; GDSC2 4.5791 7.0202 2.3858 3.1161
MHH-CALL-2 GDSC1; GDSC2 4.5843 8.913 1.4957 8.301
SUP-M2 GDSC1; GDSC2 4.6023 5.7736 2.9288 0.4638
DG-75 GDSC1; GDSC2 4.617 9.2265 1.3668 8.9839
OCI-AML-5 GDSC1; GDSC2 4.6553 5.7032 2.977 0.2837
L-363 GDSC1; GDSC2 4.6561 12.8523 -0.3822 18.0801
Kasumi-1 GDSC2 4.6608 8.9437 1.5334 7.9131
Raji GDSC1; GDSC2 4.6647 6.6578 2.5954 1.8663
EM-2 GDSC1; GDSC2 4.6652 7.0184 2.4368 2.6972
LP-1 GDSC1; GDSC2 4.6717 8.5679 1.7206 6.7905
JeKo-1 GDSC1; GDSC2 4.6946 6.309 2.758 1.0585
MN-60 GDSC1; GDSC2 4.7121 6.6991 2.6028 1.7671
KM-H2 GDSC1; GDSC2 4.7438 6.6275 2.6497 1.4997
MOLT-4 GDSC1; GDSC2 4.7477 6.5928 2.6663 1.4167
OCI-M1 GDSC1; GDSC2 4.7851 6.1598 2.8588 0.5781
H9 GDSC1; GDSC2 4.8161 6.8276 2.602 1.6406
P31/FUJ GDSC1; GDSC2 4.8397 5.9369 2.964 0.2342
L-540 GDSC1; GDSC2 4.84 6.6297 2.6965 1.1784
KE-37 GDSC1; GDSC2 4.8519 6.1504 2.8905 0.4295
697 GDSC1; GDSC2 4.8958 6.4554 2.7923 0.7362
ALL-SIL GDSC1; GDSC2 4.8969 6.6519 2.7145 1.0447
CML-T1 GDSC1; GDSC2 4.8983 6.3645 2.8287 0.6027
Daudi GDSC1; GDSC2 4.9252 6.7863 2.6733 1.1926
PF-382 GDSC1; GDSC2 4.9284 7.3553 2.4344 2.3258
MHH-CALL-4 GDSC2 4.9362 8.3766 1.9796 4.7834
SU-DHL-10 GDSC1; GDSC2 4.9574 5.8551 3.035 0.0742
TUR GDSC1; GDSC2 4.9649 7.7715 2.2713 3.1258
OCI-AML-3 GDSC1; GDSC2 4.971 6.3159 2.8773 0.4017
RC-K8 GDSC1; GDSC2 4.9801 6.6957 2.7354 0.8851
Karpas-299 GDSC1; GDSC2 4.9923 12.5565 0.0119 15.4151
PL-21 GDSC1; GDSC2 5.0006 7.3093 2.4923 1.9432
OCI-AML-2 GDSC1; GDSC2 5.0007 6.267 2.907 0.3059
BONNA-12 GDSC2 5.0068 9.0681 1.7023 6.2324
U-698-M GDSC1; GDSC2 5.0115 6.8547 2.6862 1.0547
AMO1 GDSC1; GDSC2 5.013 6.168 2.9472 0.2072
SU-DHL-8 GDSC1; GDSC2 5.0207 6.4986 2.8294 0.5194
GA-10 GDSC1; GDSC2 5.0225 6.2805 2.9106 0.2873
K-562 GDSC1; GDSC2 5.0456 6.3164 2.9065 0.2875
MOLP-8 GDSC1; GDSC2 5.0779 6.5635 2.8285 0.4876
Namalwa GDSC1; GDSC2 5.0792 6.6404 2.8001 0.5772
KG-1 GDSC1; GDSC2 5.0799 7.0788 2.6278 1.2346
SKM-1 GDSC1; GDSC2 5.0854 10.5746 1.0391 9.8309
DoHH2 GDSC1; GDSC2 5.0872 6.8262 2.7319 0.8108
JVM-2 GDSC1; GDSC2 5.0874 7.3721 2.5101 1.7542
NOMO-1 GDSC1; GDSC2 5.0975 6.7029 2.784 0.6186
ALL-PO GDSC1; GDSC2 5.1084 11.6238 0.5491 12.4324
Sc-1 GDSC1 5.1177 6.5863 2.8362 0.5505
Farage GDSC1; GDSC2 5.1247 6.6921 2.7995 0.5501
SK-MM-2 GDSC1; GDSC2 5.1265 6.7531 2.7771 0.6223
Loucy GDSC1; GDSC2 5.1296 6.6996 2.7987 0.5497
Karpas-422 GDSC1; GDSC2 5.1601 10.6314 1.0623 9.5447
CCRF-CEM GDSC1; GDSC2 5.1705 6.93 2.728 0.7616
Jurkat GDSC1; GDSC2 5.1756 6.7131 2.8126 0.4799
L-1236 GDSC1; GDSC2 5.1766 7.2259 2.6137 1.2007
SUP-B8 GDSC1; GDSC2 5.1822 7.1048 2.6647 0.9898
ST486 GDSC1; GDSC2 5.189 6.8798 2.7553 0.6539
SUP-T1 GDSC1; GDSC2 5.1894 7.1813 2.6376 1.0912
MM1.S GDSC1; GDSC2 5.2028 6.6204 2.8575 0.3416
MOLT-13 GDSC1; GDSC2 5.2037 7.1326 2.6634 0.9766
HC-1 GDSC1; GDSC2 5.2144 6.9748 2.7297 0.724
HAL-01 GDSC1; GDSC2 5.2229 7.3134 2.6 1.214
Reh GDSC1; GDSC2 5.2246 6.9922 2.7274 0.7249
RPMI-8226 GDSC1; GDSC2 5.2377 10.1165 1.3578 7.7389
Karpas-620 GDSC1; GDSC2 5.2511 6.6519 2.8647 0.3031
WSU-DLCL2 GDSC1; GDSC2 5.2538 6.3432 2.9733 0.1
WSU-NHL GDSC1; GDSC2 5.2548 7.0806 2.7063 0.7771
ME1 GDSC1; GDSC2 5.2559 6.7887 2.8169 0.4245
NALM-6 GDSC1; GDSC2 5.2582 9.0537 1.8637 4.8735
SUP-HD1 GDSC1; GDSC2 5.2644 7.7725 2.4311 1.9186
ML-2 GDSC1; GDSC2 5.2683 6.9931 2.7456 0.6338
WIL2 NS GDSC1; GDSC2 5.2958 6.7065 2.8622 0.2911
NU-DUL-1 GDSC1; GDSC2 5.2973 6.5269 2.9259 0.1622
A3/Kawakami GDSC1; GDSC2 5.317 6.4432 2.9615 0.1038
EB2 GDSC1; GDSC2 5.3416 6.8653 2.8227 0.3683
IM-9 GDSC1; GDSC2 5.3548 6.5606 2.9348 0.1339
MOLM-13 GDSC1; GDSC2 5.3579 10.5728 1.2204 8.2691
GR-ST GDSC1; GDSC2 5.3657 8.0225 2.3771 2.0539
KCL-22 GDSC1; GDSC2 5.368 6.9247 2.8114 0.3853
DND-41 GDSC1; GDSC2 5.3735 7.2125 2.7065 0.6943
CESS GDSC1; GDSC2 5.3919 6.8216 2.8575 0.2658
SU-DHL-16 GDSC1; GDSC2 5.3927 7.2445 2.7024 0.6952
KMS-11 GDSC1; GDSC2 5.4195 9.6893 1.6701 5.6649
MHH-PREB-1 GDSC1; GDSC2 5.4208 6.8577 2.8556 0.2598
JVM-3 GDSC1 5.4385 7.3868 2.6675 0.9745
Karpas-231 GDSC1; GDSC2 5.4399 6.7374 2.9045 0.1619
SU-DHL-4 GDSC1; GDSC2 5.4406 6.9684 2.8237 0.3238
BE-13 GDSC1; GDSC2 5.4443 7.0587 2.7925 0.3992
SU-DHL-6 GDSC1; GDSC2 5.4518 7.0626 2.794 0.392
ROS-50 GDSC1; GDSC2 5.4732 7.9437 2.4625 1.5532
GDM-1 GDSC1; GDSC2 5.5297 7.6823 2.5927 0.9817
Karpas-1106P GDSC1; GDSC2 5.5385 7.0667 2.8256 0.2825
LC4-1 GDSC1; GDSC2 5.5403 7.662 2.6052 0.9282
CA46 GDSC1; GDSC2 5.5519 8.0377 2.4616 1.4804
P12-Ichikawa GDSC1; GDSC2 5.5622 6.9037 2.891 0.1542
Ku812 GDSC1; GDSC2 5.5984 7.3988 2.7289 0.4958
RPMI-8402 GDSC1; GDSC2 5.6023 7.1258 2.8285 0.2548
BC-3 GDSC2 5.6198 7.0254 2.8698 0.1744
ARH-77 GDSC1; GDSC2 5.6394 7.3375 2.7672 0.3772
Granta-519 GDSC1; GDSC2 5.6481 7.6462 2.657 0.6808
SUP-B15 GDSC1; GDSC2 5.6515 7.3474 2.7683 0.3697
ATN-1 GDSC1; GDSC2 5.6867 7.2242 2.8251 0.2352
Jiyoye GDSC1; GDSC2 5.6939 7.6054 2.6909 0.5533
OCI-Ly19 GDSC1; GDSC2 5.6974 7.2585 2.817 0.2474
VAL GDSC1; GDSC2 5.7002 7.3063 2.8013 0.2781
CTV-1 GDSC1; GDSC2 5.7018 7.4213 2.761 0.3665
RCH-ACV GDSC1; GDSC2 5.7035 7.6732 2.6696 0.6103
KY821 GDSC1; GDSC2 5.7054 6.9192 2.9353 0.0736
MY-M12 GDSC1; GDSC2 5.7195 7.908 2.5876 0.8621
A4/Fukuda GDSC1; GDSC2 5.767 7.1638 2.8745 0.1349
EHEB GDSC1 5.786 7.5331 2.7531 0.4383
HDLM-2 GDSC1; GDSC2 5.7922 7.7633 2.672 0.5558
Mono-Mac-6 GDSC1; GDSC2 5.8067 8.4827 2.4011 1.4931
JJN-3 GDSC1; GDSC2 5.808 7.3115 2.8386 0.1792
EoL-1 GDSC1; GDSC2 5.8104 7.5092 2.7707 0.3044
RPMI-8866 GDSC1; GDSC2 5.8235 7.4596 2.793 0.2553
TK [Human B-cell lymphoma] GDSC1; GDSC2 5.8236 7.1572 2.8963 0.098
THP-1 GDSC1; GDSC2 5.8243 7.6027 2.7427 0.3608
VL51 GDSC1; GDSC2 5.8261 7.4026 2.8137 0.2163
QIMR-WIL GDSC1; GDSC2 5.916 12.1195 0.8514 9.1832
U266B1 GDSC1; GDSC2 5.9929 7.5108 2.8359 0.1436
EJM GDSC1; GDSC2 6.005 7.6257 2.801 0.1922
CTB-1 GDSC1; GDSC2 6.0373 17.033 -1.4235 19.176
Karpas-45 GDSC1; GDSC2 6.0483 7.5269 2.8496 0.1165
HH [Human lymphoma] GDSC1; GDSC2 6.0651 7.9635 2.7052 0.355
CRO-AP2 GDSC1; GDSC2 6.0657 7.8109 2.7589 0.2481
P30/OHK GDSC1; GDSC2 6.0828 7.3179 2.9303 0.0414
JSC-1 GDSC1; GDSC2 6.0995 8.034 2.6931 0.3689
NKM-1 GDSC1; GDSC2 6.3542 8.181 2.7349 0.2147
MEG-01 GDSC1; GDSC2 6.4294 8.4315 2.6754 0.2971
KMOE-2 GDSC1; GDSC2 6.8324 15.6208 -0.2059 12.5961
BV-173 GDSC1; GDSC2 7.3335 20.5388 -2.2161 19.3505
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCE-4 GDSC1; GDSC2 4.6711 6.4046 2.7068 1.3161
ESO-51 GDSC1; GDSC2 5.0055 7.0215 2.6155 1.3637
KYAE-1 GDSC1; GDSC2 5.3632 8.0233 2.3755 2.0641
SK-GT-4 GDSC1; GDSC2 5.5342 7.9226 2.4997 1.3394
KYSE-50 GDSC1; GDSC2 5.6369 7.1844 2.8207 0.2593
KYSE-220 GDSC1; GDSC2 5.7415 7.6543 2.6919 0.5262
OACM5.1 C GDSC1; GDSC2 5.7425 8.994 2.1587 2.6397
FLO-1 GDSC1; GDSC2 5.7875 11.0941 1.2479 7.3166
ESO-26 GDSC1; GDSC2 5.9452 7.5726 2.7979 0.2122
OACP4 C GDSC1; GDSC2 6.2261 11.9016 1.1427 7.1147
TE-12 GDSC1; GDSC2 6.9369 13.7586 0.7197 8.0733
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 5.5369 8.4132 2.2993 2.219
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-17 GDSC1; GDSC2 3.752 7.8428 1.4092 10.8464
KP-N-YS GDSC1; GDSC2 3.9037 6.4425 2.2159 5.4805
SJNB-13 GDSC1; GDSC2 4.1041 7.6289 1.7804 7.6876
TGW GDSC1; GDSC2 4.3808 6.4996 2.5048 2.7849
SJNB-6 GDSC1; GDSC2 4.3835 6.1552 2.6616 1.9219
SK-N-BE(2)-M17 GDSC1; GDSC2 4.5475 6.5324 2.5864 2.0771
KP-N-YN GDSC1; GDSC2 4.5726 6.9584 2.41 2.992
CHP-134 GDSC1 4.59 8.9297 1.4916 10.2127
NB69 GDSC1; GDSC2 4.5965 6.4135 2.6646 1.61
SJNB-7 GDSC1; GDSC2 4.6016 9.3751 1.2841 9.4999
SK-N-AS GDSC1; GDSC2 4.6134 6.7464 2.5285 2.2852
GOTO GDSC1; GDSC2 4.7124 11.0335 0.5546 13.317
NB1 GDSC1; GDSC2 4.7173 6.2974 2.7736 0.9686
SJNB-14 GDSC1; GDSC2 4.8195 7.0866 2.4925 2.1789
SJNB-10 GDSC1; GDSC2 4.8226 8.3094 1.9403 5.2145
SK-N-FI GDSC1; GDSC2 4.8545 6.698 2.6754 1.2566
SK-N-SH GDSC1; GDSC2 4.9149 9.0566 1.6487 6.7181
KP-N-RT-BM-1 GDSC2 5.0037 8.1704 2.1145 3.9153
IMR-5 GDSC1; GDSC2 5.1053 6.5588 2.8415 0.4335
SK-N-DZ GDSC1; GDSC2 5.164 7.7032 2.4091 2.1441
CHP-126 GDSC1; GDSC2 5.2416 6.7833 2.8132 0.4423
Kelly GDSC1; GDSC2 5.2468 6.8351 2.7961 0.4892
NB(TU)1 GDSC1 5.2545 6.9489 2.7565 0.7562
SK-N-MC-IXC GDSC1; GDSC2 5.272 6.4846 2.9314 0.1594
SJNB-5 GDSC1; GDSC2 5.3068 11.5211 0.7353 11.0142
CHP-212 GDSC1; GDSC2 5.5415 7.0513 2.8322 0.2675
MHH-NB-11 GDSC1; GDSC2 5.7298 7.9024 2.5942 0.833
NH-12 GDSC1; GDSC2 5.8273 8.2017 2.521 1.018
LA-N-6 GDSC1; GDSC2 6.0128 7.5932 2.8149 0.1692
SJNB-12 GDSC1; GDSC2 6.049 7.9592 2.7007 0.3708
SiMa GDSC1 6.1748 8.347 2.6094 0.671
GI-ME-N GDSC1; GDSC2 6.7094 8.8147 2.6439 0.2763
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; GDSC2 4.6453 6.3222 2.7283 1.2456
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAMA-1 GDSC1; GDSC2 3.8139 5.6406 2.5426 3.6739
DU4475 GDSC1; GDSC2 4.0081 5.7344 2.6284 2.7511
Evsa-T GDSC1; GDSC2 4.2263 5.5288 2.8499 1.1705
HCC1187 GDSC1; GDSC2 4.3801 7.2086 2.1739 4.7041
HCC2157 GDSC1; GDSC2 4.5344 6.3318 2.6669 1.6801
ZR-75-30 GDSC1; GDSC2 4.5379 6.225 2.7147 1.4382
HCC70 GDSC1; GDSC2 4.6127 9.7334 1.1178 10.4336
HCC1599 GDSC2 4.7034 9.5293 1.2805 9.2929
UACC-893 GDSC1; GDSC2 4.7492 7.215 2.3968 2.7828
HDQ-P1 GDSC1; GDSC2 4.7652 6.9318 2.5305 2.0594
MDA-MB-415 GDSC1; GDSC2 4.7865 7.6374 2.2281 3.6466
CAL-120 GDSC1; GDSC2 4.7873 6.8279 2.5869 1.7491
BT-549 GDSC1; GDSC2 4.8748 7.6871 2.2574 3.3408
AU565 GDSC1; GDSC2 4.9261 7.9244 2.1802 3.6806
HCC1954 GDSC1; GDSC2 4.9296 7.2807 2.4673 2.1578
JIMT-1 GDSC1; GDSC2 4.9362 7.5353 2.3598 2.7002
HCC1395 GDSC1; GDSC2 5.0303 7.8524 2.2722 3.0226
HCC1937 GDSC1; GDSC2 5.0324 6.9229 2.6685 1.1084
HCC1500 GDSC1; GDSC2 5.0602 6.9936 2.653 1.1468
MFM-223 GDSC1; GDSC2 5.1219 6.8834 2.7249 0.8097
CAL-148 GDSC2 5.1536 6.7186 2.8015 0.5262
BT-483 GDSC1 5.1662 6.627 2.8407 0.5031
BT-20 GDSC1; GDSC2 5.1722 6.771 2.7895 0.5528
BT-474 GDSC1; GDSC2 5.1914 6.404 2.9302 0.184
OCUB-M GDSC1; GDSC2 5.2055 7.6648 2.4467 1.9142
EFM-19 GDSC1; GDSC2 5.2381 7.5076 2.5282 1.5062
MCF-7 GDSC1; GDSC2 5.3269 7.7099 2.488 1.5911
MDA-MB-453 GDSC1; GDSC2 5.3576 7.623 2.5381 1.3451
HCC1806 GDSC1; GDSC2 5.3653 11.4818 0.7936 10.5799
HCC1428 GDSC1; GDSC2 5.3818 7.3748 2.6475 0.8942
HCC1569 GDSC1; GDSC2 5.3877 7.6033 2.56 1.227
HCC2218 GDSC1; GDSC2 5.4057 7.343 2.6703 0.7957
EFM-192A GDSC1; GDSC2 5.4224 7.1783 2.7397 0.559
HCC38 GDSC1; GDSC2 5.4663 7.342 2.6963 0.6681
MRK-nu-1 GDSC1; GDSC2 5.6032 6.9869 2.8771 0.1666
HCC1419 GDSC1 5.618 20.1753 -3.2761 28.409
MDA-MB-361 GDSC1; GDSC2 5.6323 7.431 2.7305 0.4746
MDA-MB-231 GDSC1; GDSC2 5.7633 7.6801 2.6911 0.5175
MDA-MB-157 GDSC1; GDSC2 5.7948 7.7571 2.6753 0.5452
HCC202 GDSC1 5.8304 7.7372 2.6966 0.5863
CAL-85-1 GDSC1; GDSC2 5.9396 8.487 2.4592 1.1569
HCC1143 GDSC1; GDSC2 5.9839 9.1482 2.2145 2.1115
MDA-MB-175-VII GDSC1; GDSC2 5.9908 7.5856 2.8097 0.182
Hs 578T GDSC1; GDSC2 6.1113 8.8609 2.3889 1.2832
CAL-51 GDSC1; GDSC2 6.1191 7.666 2.8273 0.1317
MDA-MB-436 GDSC1; GDSC2 6.1497 7.9773 2.7316 0.2741
MDA-MB-468 GDSC1; GDSC2 6.1743 14.3949 -0.0559 13.1751
YMB-1-E GDSC2 6.2178 7.9669 2.7597 0.2075
T-47D GDSC1; GDSC2 6.2307 8.9657 2.4004 1.1518
COLO 824 GDSC1; GDSC2 6.5005 8.4389 2.6985 0.238
MDA-MB-330 GDSC1; GDSC2 7.2855 15.0567 0.3362 9.3316
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1088 GDSC1; GDSC2 2.7872 7.2105 0.9158 16.6777
GaMG GDSC1; GDSC2 3.6431 7.0282 1.7292 9.1693
SF539 GDSC1; GDSC2 4.1328 6.1217 2.5263 3.1101
U-251MG GDSC1; GDSC2 4.1473 6.5403 2.3377 4.2003
SNB-75 GDSC1; GDSC2 4.2357 7.6393 1.8692 6.8427
Onda 10 GDSC1; GDSC2 4.3834 7.2747 2.1447 4.8702
42-MG-BA GDSC1; GDSC2 4.5515 6.6615 2.5313 2.3635
CAS-1 GDSC1; GDSC2 4.5552 7.8825 1.9694 5.5624
Hs 683 GDSC1; GDSC2 4.5574 8.9423 1.4629 8.5535
U-87MG ATCC GDSC1; GDSC2 4.5926 9.6783 1.1303 10.4085
KNS-42 GDSC1; GDSC2 4.5997 6.336 2.6994 1.436
LN-229 GDSC1; GDSC2 4.6342 6.4599 2.6645 1.5626
YKG-1 GDSC1; GDSC2 4.6766 7.75 2.1093 4.5133
D-542MG GDSC1; GDSC2 4.6847 6.4812 2.6814 1.4194
SF295 GDSC1; GDSC2 4.6999 10.9856 0.569 13.2701
DK-MG GDSC1; GDSC2 4.7782 7.9085 2.0987 4.3895
MOG-G-CCM GDSC1; GDSC2 4.8161 7.7124 2.2115 3.6893
M059J GDSC1; GDSC2 4.8222 7.0957 2.49 2.1881
8-MG-BA GDSC1; GDSC2 4.8856 6.5534 2.7489 0.9137
GI-1 GDSC1; GDSC2 4.9296 11.4831 0.4912 13.1422
PFSK-1 GDSC1; GDSC2 4.9542 10.6642 0.9061 10.8524
D-502MG GDSC1; GDSC2 5.0286 8.7731 1.8533 5.3327
D283 Med GDSC1; GDSC2 5.0511 7.3116 2.5172 1.763
KNS-81-FD GDSC1; GDSC2 5.0614 7.115 2.6041 1.3555
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 5.0739 7.7841 2.3263 2.678
D-247MG GDSC1; GDSC2 5.1235 8.0175 2.2511 2.9969
LN-405 GDSC1; GDSC2 5.1399 7.5644 2.4557 1.9492
YH-13 GDSC1; GDSC2 5.146 8.7414 1.9392 4.6459
D-423MG GDSC1; GDSC2 5.1747 11.5506 0.6306 11.8557
MOG-G-UVW GDSC1; GDSC2 5.243 7.9896 2.3278 2.4427
SK-MG-1 GDSC1; GDSC2 5.2503 8.1665 2.2552 2.7973
NMC-G1 GDSC1; GDSC2 5.2726 6.792 2.8223 0.4014
Daoy GDSC1; GDSC2 5.2842 6.9432 2.771 0.5434
Onda 11 GDSC1; GDSC2 5.2868 8.535 2.1135 3.4793
SW1783 GDSC1; GDSC2 5.2896 7.6894 2.4783 1.6742
AM-38 GDSC1; GDSC2 5.3109 11.2265 0.8791 10.2336
ONS-76 GDSC1; GDSC2 5.3608 12.2668 0.4135 12.5784
D-263MG GDSC1; GDSC2 5.3934 6.9576 2.8094 0.379
T98G GDSC1; GDSC2 5.4102 7.2548 2.7058 0.6727
H4 GDSC1; GDSC2 5.4289 7.8883 2.464 1.5913
SF126 GDSC1; GDSC2 5.4408 7.0749 2.7852 0.4201
SF268 GDSC1; GDSC2 5.4962 7.7817 2.5385 1.2169
D-245MG GDSC2 5.5334 8.6707 2.1881 2.758
U-118MG GDSC1; GDSC2 5.6235 7.3523 2.7557 0.4127
Becker GDSC1; GDSC2 5.6263 6.9575 2.8953 0.134
D-566MG GDSC1; GDSC2 5.6292 8.3449 2.3732 1.7825
D-392MG GDSC1; GDSC2 5.6365 8.6119 2.266 2.2591
D-336MG GDSC1; GDSC2 5.6372 7.987 2.521 1.1659
KALS-1 GDSC1; GDSC2 5.7095 8.5985 2.3077 1.988
DBTRG-05MG GDSC1; GDSC2 5.7324 10.6013 1.4409 6.3745
A-172 GDSC1; GDSC2 5.7376 8.6567 2.2974 2.0038
LNZTA3WT4 GDSC1; GDSC2 5.9165 7.3924 2.8493 0.1402
GB-1 GDSC1; GDSC2 6.3209 7.9032 2.8172 0.1114
KINGS-1 GDSC1; GDSC2 6.5052 9.2325 2.4147 0.9231
LN-18 GDSC1; GDSC2 7.209 16.0233 -0.1556 11.6964
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 5.3684 7.601 2.552 1.2773
TGBC1TKB GDSC1; GDSC2 5.4448 6.8671 2.8612 0.24
TGBC24TKB GDSC1; GDSC2 5.8388 8.6616 2.3439 1.6996
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-319 GDSC1; GDSC2 3.1026 6.4913 1.5509 11.8396
ESS-1 GDSC1; GDSC2 4.6339 6.3805 2.6981 1.4008
EN GDSC1; GDSC2 4.9116 6.3069 2.8563 0.5011
AN3-CA GDSC1; GDSC2 5.0753 7.2159 2.5692 1.496
RL95-2 GDSC1; GDSC2 5.091 9.5915 1.5104 7.1642
KLE GDSC1; GDSC2 5.6245 10.5934 1.3789 6.8991
MFE-296 GDSC1; GDSC2 6.0187 10.773 1.5314 5.4259
MFE-280 GDSC1; GDSC2 6.2002 8.2628 2.6496 0.429
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB2241-RCC GDSC1; GDSC2 3.2831 6.6152 1.6428 10.7227
A-498 GDSC1; GDSC2 3.9952 5.8388 2.5707 3.1183
KTCTL-13 GDSC1; GDSC2 4.228 8.4111 1.4873 9.1691
RCC10RGB GDSC1; GDSC2 4.2462 5.867 2.7121 1.8601
NCC010 GDSC1; GDSC2 4.3416 8.4811 1.5349 8.6164
NCC021 GDSC1; GDSC2 4.357 7.4555 2.0411 5.5421
VMRC-RCW GDSC1; GDSC2 4.3882 9.5221 1.0594 11.2995
CAL-54 GDSC1; GDSC2 4.5452 6.5681 2.5693 2.1704
786-O GDSC1; GDSC2 4.5478 6.1798 2.739 1.3087
SW156 GDSC1; GDSC2 4.7006 7.5897 2.1982 3.962
769-P GDSC1; GDSC2 4.7754 10.1552 1.0277 10.5744
BB65-RCC GDSC1; GDSC2 4.8384 14.0958 -0.8593 19.6946
KMRC-20 GDSC1; GDSC2 4.9113 6.9886 2.5825 1.6195
ACHN GDSC1; GDSC2 4.9831 8.7804 1.8216 5.5954
Caki-1 GDSC1; GDSC2 5.0964 16.4546 -1.8306 22.7185
KTCTL-26A GDSC1; GDSC2 5.1454 14.1833 -0.6741 18.1821
KTCTL-1M GDSC1; GDSC2 5.1514 13.6531 -0.4096 17.0098
BFTC-909 GDSC1; GDSC2 5.1711 9.0541 1.8111 5.3158
LB1047-RCC GDSC1; GDSC2 5.3503 14.0009 -0.436 16.6697
LB996-RCC GDSC1; GDSC2 5.3818 7.5866 2.564 1.2162
KMRC-1 GDSC1; GDSC2 5.4665 7.0794 2.7936 0.3864
OS-RC-2 GDSC1; GDSC2 5.5777 7.7536 2.586 0.9697
SW13 GDSC1; GDSC2 5.6303 7.2643 2.79 0.3275
SN12C GDSC1; GDSC2 5.6519 7.4784 2.7209 0.4911
A-704 GDSC1; GDSC2 5.7929 7.4745 2.7764 0.2984
KTCTL-195 GDSC1; GDSC2 5.8995 14.0781 -0.0892 13.8902
RXF 393L GDSC1; GDSC2 5.9891 8.7943 2.3603 1.4948
UO-31 GDSC1; GDSC2 6.0831 8.4605 2.5306 0.8148
HA7-RCC GDSC1; GDSC2 6.1487 13.5552 0.3258 11.4013
TK-10 GDSC1; GDSC2 6.2455 8.5544 2.5615 0.6332
VMRC-RCZ GDSC1; GDSC2 6.4849 8.0526 2.8232 0.0845
KTCTL-140 GDSC1; GDSC2 6.975 17.5043 -1.0046 15.6894
KTCTL-21 GDSC1; GDSC2 7.1847 16.2092 -0.2574 12.1875
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H716 GDSC1; GDSC2 4.1392 6.3414 2.4269 3.6846
HCT 15 GDSC1; GDSC2 4.2563 5.6874 2.7972 1.3964
SW837 GDSC1; GDSC2 4.2736 5.9465 2.6922 1.9251
HT115 GDSC1; GDSC2 4.3064 5.5957 2.8628 1.0086
HCC2998 GDSC1; GDSC2 4.35 6.4698 2.4999 2.8659
KM12 GDSC1; GDSC2 4.7353 7.2479 2.3742 2.9264
COLO205 GDSC1; GDSC2 4.778 6.232 2.8275 0.6977
CL-11 GDSC1; GDSC2 4.7903 6.8731 2.5692 1.8325
SNU-C5 GDSC1; GDSC2 4.8171 7.285 2.404 2.6419
HT-29 GDSC1; GDSC2 4.9019 6.4557 2.7949 0.7219
SNU-81 GDSC1; GDSC2 5.0124 6.6392 2.7719 0.7214
SNU-C2B GDSC1; GDSC2 5.0478 7.5697 2.4054 2.3117
MDST8 GDSC1; GDSC2 5.1175 6.907 2.7137 0.855
SNU-175 GDSC2 5.1353 7.162 2.6202 1.213
HCT 116 GDSC1; GDSC2 5.1613 6.5612 2.8628 0.3468
SNU-407 GDSC1; GDSC2 5.2279 7.6937 2.4458 1.892
SW620 GDSC1; GDSC2 5.2464 8.9976 1.8823 4.7913
LS1034 GDSC1; GDSC2 5.2512 6.7723 2.8211 0.4153
SNU-283 GDSC2 5.2739 6.9612 2.76 0.5839
SW1417 GDSC1; GDSC2 5.2922 8.6336 2.0728 3.6863
GP5d GDSC1; GDSC2 5.323 6.9485 2.7848 0.4806
LoVo GDSC1; GDSC2 5.3355 8.6525 2.0887 3.5374
SW48 GDSC1; GDSC2 5.3517 7.4481 2.6053 1.0779
COLO 320HSR GDSC1; GDSC2 5.3567 6.877 2.8243 0.3574
LS180 GDSC1; GDSC2 5.3675 7.0115 2.7794 0.4726
RCM-1 [Human ESC] GDSC1; GDSC2 5.3726 6.5313 2.951 0.1072
LS411N GDSC1; GDSC2 5.3992 6.5281 2.9613 0.0897
T84 GDSC1; GDSC2 5.4081 7.3304 2.6761 0.7737
SW948 GDSC1; GDSC2 5.4131 6.6358 2.9297 0.1288
SNU-61 GDSC1; GDSC2 5.4295 7.2605 2.7117 0.6414
RKO GDSC1; GDSC2 5.4566 7.489 2.6359 0.8802
HT-55 GDSC1; GDSC2 5.4973 6.6972 2.9384 0.1011
CaR-1 GDSC1; GDSC2 5.5779 7.1008 2.8282 0.2634
SW1463 GDSC1; GDSC2 5.684 7.9906 2.5403 1.0556
LS513 GDSC1; GDSC2 5.758 7.3399 2.8108 0.241
SW1116 GDSC1; GDSC2 5.7594 7.1016 2.8929 0.1124
NCI-H747 GDSC1; GDSC2 5.7873 7.8005 2.6563 0.6034
COLO 678 GDSC1; GDSC2 5.788 7.4722 2.7754 0.3022
C2BBe1 GDSC1; GDSC2 5.8407 7.7163 2.7082 0.4367
CCK-81 GDSC1; GDSC2 5.8959 7.6029 2.7694 0.2787
SW626 GDSC1; GDSC2 5.8988 9.0928 2.1958 2.2864
NCI-H508 GDSC1; GDSC2 5.984 7.2778 2.9106 0.0639
CW-2 GDSC1; GDSC2 6.0029 8.0268 2.6587 0.49
SK-CO-1 GDSC1; GDSC2 6.0596 7.7989 2.7609 0.2462
DiFi GDSC1; GDSC2 6.0735 8.3114 2.5823 0.6637
SNU-C1 GDSC1; GDSC2 6.0757 7.6718 2.8102 0.1628
LS123 GDSC1; GDSC2 6.2865 8.1738 2.7131 0.269
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 5.5314 7.1572 2.7906 0.3657
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-6 GDSC1; GDSC2 3.879 5.3282 2.7364 2.3663
JHH-4 GDSC1; GDSC2 4.589 6.3801 2.675 1.5683
Huh-7 GDSC1; GDSC2 4.6122 6.9487 2.4375 2.7763
SK-HEP-1 GDSC1; GDSC2 4.6408 5.8924 2.8996 0.5383
SNU-423 GDSC1; GDSC2 4.698 6.681 2.6031 1.7836
JHH-2 GDSC1; GDSC2 4.7461 7.8729 2.0954 4.4657
SNU-398 GDSC1; GDSC2 4.8076 7.8865 2.1268 4.1781
JHH-1 GDSC1; GDSC2 5.0387 6.4155 2.8677 0.3935
HuH-1 GDSC1; GDSC2 5.1535 9.1589 1.7519 5.6791
JHH-7 GDSC1; GDSC2 5.2335 8.4943 2.1016 3.6224
Hep-G2/C3A GDSC1; GDSC2 5.3576 6.5388 2.9432 0.121
SNU-387 GDSC1; GDSC2 5.5318 8.6833 2.1818 2.791
HLE GDSC1; GDSC2 5.8101 11.9878 0.8456 9.4143
SNU-449 GDSC1; GDSC2 5.9273 7.7192 2.7401 0.3287
Hep 3B2.1-7 GDSC1; GDSC2 6.2498 17.0713 -1.292 18.2387
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 186 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2030 GDSC1; GDSC2 3.0916 11.4854 -0.9533 24.8581
NCI-H1666 GDSC1; GDSC2 3.4936 5.4191 2.4128 5.276
BEN GDSC1; GDSC2 3.7296 6.6664 1.9761 7.4016
NCI-H82 GDSC1; GDSC2 3.7334 4.9665 2.8121 2.2095
NCI-H292 GDSC1; GDSC2 3.7646 7.1734 1.7515 8.7093
NCI-H1581 GDSC1; GDSC2 3.811 5.9357 2.3969 4.5788
NCI-H196 GDSC1; GDSC2 3.8758 6.1552 2.3362 4.803
COR-L95 GDSC1; GDSC2 3.8767 5.4059 2.6981 2.5978
NCI-H720 GDSC1 3.8977 5.6874 2.5778 4.0817
LCLC-103H GDSC1; GDSC2 3.9192 6.3844 2.2554 5.2007
NCI-H1355 GDSC1; GDSC2 4.0299 7.0665 2.0019 6.5046
NCI-H2009 GDSC1; GDSC2 4.0787 6.1066 2.4985 3.3797
NCI-H1650 GDSC1; GDSC2 4.081 7.0423 2.0501 6.0906
NCI-H1304 GDSC1 4.1778 7.8345 1.7331 9.649
COR-L23 GDSC1; GDSC2 4.2084 6.6828 2.3104 4.2382
HCC78 GDSC1; GDSC2 4.2116 13.8596 -1.225 22.7335
NCI-H835 GDSC1; GDSC2 4.333 7.8287 1.8454 6.7698
COR-L279 GDSC1; GDSC2 4.3712 7.0757 2.2309 4.3847
NCI-H2369 GDSC1; GDSC2 4.3767 9.3616 1.1297 10.922
Ms-1 GDSC1; GDSC2 4.4049 6.3984 2.565 2.4106
IA-LM GDSC1; GDSC2 4.4383 6.9688 2.3237 3.7158
NCI-H2172 GDSC1; GDSC2 4.4406 6.0367 2.7444 1.4159
HCC366 GDSC1; GDSC2 4.462 6.1679 2.6992 1.6147
NCI-H1299 GDSC1; GDSC2 4.5132 11.7092 0.075 16.2717
NCI-H748 GDSC2 4.5275 8.5554 1.629 7.6381
NCI-H838 GDSC1; GDSC2 4.5762 7.6097 2.1115 4.6882
NCI-H64 GDSC1; GDSC2 4.5848 5.7644 2.9249 0.4896
SK-LU-1 GDSC1; GDSC2 4.6261 7.6048 2.1453 4.399
NCI-H2444 GDSC1; GDSC2 4.6638 6.3431 2.7288 1.2224
ChaGo-K-1 GDSC1; GDSC2 4.6747 7.6807 2.1402 4.3389
NCI-H23 GDSC1; GDSC2 4.6914 6.9774 2.4699 2.48
HOP-92 GDSC1; GDSC2 4.702 8.2282 1.9015 5.6694
Lu-135 GDSC1; GDSC2 4.722 6.8405 2.5469 2.035
NCI-H2810 GDSC1; GDSC2 4.7489 8.5816 1.7651 6.3729
NCI-H2135 GDSC1; GDSC2 4.7516 8.559 1.7775 6.2951
NCI-H2081 GDSC1; GDSC2 4.7687 7.2784 2.3797 2.8449
HOP-62 GDSC1; GDSC2 4.7803 9.9392 1.1358 9.9515
NCI-H1838 GDSC1; GDSC2 4.7949 8.3389 1.909 5.4468
NCI-H345 GDSC1; GDSC2 4.8137 5.836 2.9901 0.1854
NCI-H2795 GDSC1; GDSC2 4.8149 8.7993 1.7052 6.5899
LOU-NH91 GDSC1; GDSC2 4.8186 8.0605 2.0534 4.5749
RERF-LC-KJ GDSC1; GDSC2 4.8266 6.7988 2.6195 1.5444
NCI-H250 GDSC2 4.8574 7.2195 2.4551 2.318
NCI-H1155 GDSC1; GDSC2 4.8597 7.2399 2.4474 2.3541
SBC-5 GDSC1; GDSC2 4.8656 5.7353 3.0436 0.0796
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2 4.866 6.9007 2.5965 1.6066
NCI-H2023 GDSC1; GDSC2 4.8713 7.4504 2.3611 2.7884
NCI-H1092 GDSC1; GDSC2 4.8829 6.7249 2.6781 1.215
NCI-H661 GDSC1; GDSC2 4.8878 9.7688 1.2917 8.8279
NCI-H322M GDSC1; GDSC2 4.9294 8.332 1.996 4.7027
NCI-H1876 GDSC1; GDSC2 4.9506 6.6169 2.7532 0.8405
NCI-H1693 GDSC1; GDSC2 4.9658 7.664 2.3195 2.8683
CAL-12T GDSC1; GDSC2 4.9706 7.2016 2.5227 1.8335
EMC-BAC-1 GDSC1; GDSC2 4.9865 8.537 1.9365 4.9379
NCI-H1105 GDSC1; GDSC2 4.9887 6.7449 2.7197 0.9396
NCI-H3255 GDSC1; GDSC2 4.9913 8.3869 2.0084 4.5249
NCI-H2291 GDSC1; GDSC2 4.9963 7.2626 2.51 1.8632
NCI-H740 GDSC2 5.0328 8.1281 2.1505 3.6712
NCI-H146 GDSC1; GDSC2 5.0458 7.5021 2.4334 2.1748
NCI-H2228 GDSC1; GDSC2 5.0509 7.5597 2.4113 2.2779
NCI-H460 GDSC1; GDSC2 5.0624 6.2236 2.9459 0.1933
NCI-H647 GDSC1; GDSC2 5.0813 8.2678 2.1157 3.783
NCI-H810 GDSC1; GDSC2 5.0983 6.6365 2.8096 0.5345
NCI-H2066 GDSC1; GDSC2 5.1046 6.859 2.7268 0.8162
LC-2/ad GDSC1; GDSC2 5.1123 7.684 2.3903 2.3023
SBC-1 GDSC1; GDSC2 5.1174 6.9317 2.7039 0.8923
NCI-H211 GDSC1; GDSC2 5.1183 8.4032 2.0762 3.9388
COR-L321 GDSC1; GDSC2 5.1256 6.6042 2.8328 0.4477
DMS 79 GDSC1; GDSC2 5.127 6.9821 2.6883 0.9444
Lu-165 GDSC1; GDSC2 5.1309 6.7985 2.7616 0.6719
NCI-H1341 GDSC1; GDSC2 5.1354 6.7112 2.7968 0.5523
DMS 53 GDSC1; GDSC2 5.1357 7.0493 2.6656 1.0263
NCI-H1437 GDSC1; GDSC2 5.1465 7.3895 2.5323 1.5855
KNS-62 GDSC1; GDSC2 5.1507 7.0445 2.6744 0.9787
NCI-H1792 GDSC1; GDSC2 5.1537 6.609 2.8423 0.4057
NCI-H2110 GDSC1; GDSC2 5.1591 8.6052 2.0088 4.2409
HCC33 GDSC2 5.1685 7.918 2.3191 2.5847
NCI-H1436 GDSC1; GDSC2 5.1701 6.5766 2.8606 0.3484
COR-L311 GDSC2 5.1901 6.9842 2.7155 0.7919
NCI-H2171 GDSC2 5.1946 6.6338 2.8494 0.3663
NCI-H1755 GDSC1; GDSC2 5.224 8.0684 2.2836 2.689
NCI-H520 GDSC1; GDSC2 5.2581 6.8592 2.7917 0.4958
PC-14 GDSC1; GDSC2 5.2613 8.1874 2.252 2.7983
NCI-H1781 GDSC1; GDSC2 5.2617 6.7521 2.8326 0.3791
NCI-H1563 GDSC1; GDSC2 5.2672 7.83 2.4083 2.0224
Lu-65 GDSC1; GDSC2 5.2716 7.0798 2.7139 0.7387
NCI-H522 GDSC1; GDSC2 5.2725 6.9792 2.7526 0.6083
HCC15 GDSC1; GDSC2 5.2917 7.7463 2.4557 1.774
NCI-H2196 GDSC2 5.3021 6.8731 2.8043 0.4362
HCC827 GDSC1; GDSC2 5.3094 7.7173 2.4764 1.6611
NCI-H727 GDSC1; GDSC2 5.3207 7.717 2.4821 1.6239
EBC-1 GDSC1; GDSC2 5.326 9.9798 1.4781 6.8973
NCI-H2141 GDSC1; GDSC2 5.3417 6.7197 2.8748 0.2464
SK-MES-1 GDSC1; GDSC2 5.3444 9.9473 1.5047 6.7149
NCI-H1770 GDSC1; GDSC2 5.3569 7.0994 2.7423 0.5891
HCC44 GDSC1; GDSC2 5.3648 7.7235 2.5006 1.4972
VMRC-LCD GDSC1; GDSC2 5.3723 6.8683 2.8334 0.3283
LK-2 GDSC1; GDSC2 5.3788 7.2901 2.679 0.7841
NCI-H187 GDSC1 5.3805 6.4616 2.9771 0.0931
NCI-H226 GDSC1; GDSC2 5.3886 6.9921 2.7949 0.4192
NCI-H3122 GDSC1; GDSC2 5.3971 7.2393 2.7062 0.6799
NCI-H841 GDSC1; GDSC2 5.4008 10.1781 1.4327 7.0108
NCI-H2029 GDSC1; GDSC2 5.4031 6.7281 2.8945 0.1889
EMC-BAC-2 GDSC1; GDSC2 5.43 11.8138 0.6784 11.0562
NCI-H526 GDSC1; GDSC2 5.433 6.7378 2.9019 0.1679
NCI-H1836 GDSC1; GDSC2 5.4331 7.2045 2.7343 0.5693
EPLC-272H GDSC1; GDSC2 5.4383 7.3509 2.6811 0.7361
NCI-H1648 GDSC1; GDSC2 5.4456 8.6786 2.1378 3.1265
NCI-H1944 GDSC1; GDSC2 5.4492 12.7072 0.2621 13.1511
DMS 273 GDSC1; GDSC2 5.4545 10.1246 1.4909 6.5905
NCI-H2803 GDSC2 5.4551 7.5758 2.6014 1.0081
COR-L88 GDSC1; GDSC2 5.4584 7.7138 2.5483 1.2108
NCI-H1975 GDSC1; GDSC2 5.4589 7.3117 2.7047 0.6459
NCI-H1793 GDSC1; GDSC2 5.4593 7.1343 2.7708 0.45
NCI-H1915 GDSC1; GDSC2 5.4649 13.3527 -0.0393 14.585
NCI-H2722 GDSC1; GDSC2 5.4656 11.4831 0.8599 10.0185
NCI-H1694 GDSC1; GDSC2 5.4721 7.0867 2.7931 0.3851
NCI-H1435 GDSC1; GDSC2 5.4822 6.8897 2.867 0.2168
Lu-99A GDSC1; GDSC2 5.4865 8.2726 2.3329 2.1204
NCI-H1688 GDSC1; GDSC2 5.4881 8.8209 2.0988 3.2663
COR-L303 GDSC2 5.4881 6.9527 2.8471 0.2545
NCI-H209 GDSC1; GDSC2 5.516 7.9775 2.4691 1.4833
NCI-H2869 GDSC1; GDSC2 5.536 8.4319 2.2909 2.2595
A-427 GDSC1; GDSC2 5.5459 8.348 2.3311 2.0613
RERF-LC-Sq1 GDSC1; GDSC2 5.5613 10.1591 1.5403 6.1307
NCI-H2731 GDSC1; GDSC2 5.5646 8.8582 2.1238 3.0359
NCI-H290 GDSC1; GDSC2 5.5658 7.3785 2.7233 0.5282
DMS 114 GDSC1; GDSC2 5.5737 7.1364 2.8141 0.2948
SW1573 GDSC1; GDSC2 5.5767 8.9382 2.0956 3.161
NCI-H2461 GDSC1; GDSC2 5.5964 7.5888 2.6572 0.7122
NCI-H1573 GDSC1; GDSC2 5.6059 7.264 2.7808 0.3585
Calu-6 GDSC1; GDSC2 5.6203 7.3608 2.7514 0.4252
NCI-H596 GDSC1; GDSC2 5.6665 7.201 2.8258 0.24
SBC-3 GDSC1; GDSC2 5.6788 7.5677 2.6988 0.539
LCLC-97TM1 GDSC1; GDSC2 5.6789 7.9223 2.5647 0.9712
NCI-H2227 GDSC1; GDSC2 5.6982 7.2403 2.8236 0.2345
NCI-H2405 GDSC1; GDSC2 5.7074 8.0351 2.5333 1.0634
NCI-H2085 GDSC1; GDSC2 5.7086 8.0183 2.5404 1.0366
NCI-H2373 GDSC1; GDSC2 5.7112 12.9775 0.3109 12.3521
NCI-H1963 GDSC2 5.7143 7.6463 2.684 0.5625
NCI-H510A GDSC1; GDSC2 5.7193 7.4094 2.7719 0.3346
NCI-H2342 GDSC1; GDSC2 5.7204 9.093 2.105 2.9262
LB647-SCLC GDSC1; GDSC2 5.7217 7.7004 2.6669 0.6081
NCI-H524 GDSC1; GDSC2 5.7233 7.4981 2.7417 0.4043
A-549 GDSC1; GDSC2 5.7412 7.8678 2.6121 0.7664
NCI-H2591 GDSC1; GDSC2 5.7474 9.153 2.0935 2.9481
NCI-H69 GDSC1; GDSC2 5.7547 7.4305 2.7777 0.3089
NCI-H358 GDSC1; GDSC2 5.7765 11.9522 0.8408 9.5042
NCI-H2122 GDSC1; GDSC2 5.8475 7.3621 2.8353 0.1751
NCI-H446 GDSC1; GDSC2 5.8514 7.4404 2.8098 0.2164
COR-L32 GDSC2 5.8613 7.7112 2.718 0.4041
NCI-H847 GDSC1 5.8761 7.1712 2.9095 0.0961
SHP-77 GDSC1; GDSC2 5.8791 7.2657 2.8791 0.1091
Lu-139 GDSC1; GDSC2 5.8892 7.6818 2.7391 0.3445
UMC-11 GDSC1; GDSC2 5.8917 7.4171 2.8322 0.1699
NCI-H1651 GDSC1; GDSC2 5.8953 7.8969 2.6639 0.5268
CPC-N GDSC1; GDSC2 5.9037 7.5476 2.7916 0.2344
IST-SL2 GDSC1; GDSC2 5.9296 7.9444 2.66 0.5206
NCI-H1993 GDSC1; GDSC2 5.9423 7.579 2.7946 0.2186
COR-L105 GDSC1; GDSC2 5.953 9.3512 2.1149 2.5967
Calu-3 GDSC1; GDSC2 5.9698 7.6762 2.7709 0.2534
NCI-H1048 GDSC1; GDSC2 6.0146 7.5117 2.8431 0.1301
COLO 668 GDSC1; GDSC2 6.0283 7.7742 2.7581 0.2602
RERF-LC-MS GDSC1; GDSC2 6.0387 7.9626 2.6956 0.3861
NCI-H513 GDSC1; GDSC2 6.0395 8.3528 2.5531 0.7707
NCI-H2170 GDSC1; GDSC2 6.0617 7.7209 2.7885 0.1987
NCI-H650 GDSC1; GDSC2 6.0873 7.6348 2.8268 0.138
LC-1/sq GDSC1; GDSC2 6.1225 8.5919 2.4974 0.8965
PaCa-3 GDSC1; GDSC2 6.1311 8.528 2.525 0.8032
NCI-H2347 GDSC1; GDSC2 6.1623 8.0827 2.6993 0.3337
IST-SL1 GDSC1; GDSC2 6.228 7.9211 2.779 0.176
NCI-H1568 GDSC1; GDSC2 6.2934 8.8651 2.4653 0.8924
NCI-H1734 GDSC2 6.3051 8.0201 2.7724 0.1695
NCI-H1623 GDSC1; GDSC2 6.3818 8.1613 2.7514 0.1837
NCI-H441 GDSC1; GDSC2 6.4008 8.2717 2.7204 0.2267
NCI-H1869 GDSC1 6.4977 8.5816 2.648 0.4094
SW1271 GDSC1; GDSC2 6.5478 8.0678 2.8392 0.0652
Lu-134-A GDSC1; GDSC2 6.6287 9.1787 2.4844 0.6552
EKVX GDSC1; GDSC2 6.7746 9.2452 2.5167 0.5117
NCI-H2087 GDSC1; GDSC2 6.9467 16.381 -0.4903 13.6271
NCI-H2818 GDSC1; GDSC2 7.1207 16.3769 -0.3764 12.8195
NCI-H1703 GDSC1; GDSC2 7.19 17.2628 -0.7486 14.2599
NCI-H2804 GDSC1; GDSC2 7.2662 22.763 -3.3399 22.7781
NCI-H2595 GDSC1; GDSC2 7.5242 17.9701 -0.8661 14.135
LXF 289 GDSC1; GDSC2 7.8743 19.6129 -1.4139 15.6158
ABC-1 GDSC1; GDSC2 7.9132 20.4209 -1.7707 16.8176
⏷ Show the Full List of 186 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 5.3074 7.1872 2.6879 0.8041
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-180 GDSC1; GDSC2 3.6568 5.2706 2.6106 3.6186
KYSE-450 GDSC1; GDSC2 4.3097 7.1546 2.1532 4.97
KYSE-510 GDSC1; GDSC2 4.5271 8.1227 1.8364 6.4067
KYSE-150 GDSC1; GDSC2 4.6343 6.1898 2.7778 1.0338
KYSE-70 GDSC1; GDSC2 4.8005 8.3611 1.9022 5.4757
KYSE-520 GDSC1; GDSC2 4.8097 8.0633 2.0466 4.6298
TE-1 GDSC1; GDSC2 4.8241 6.9962 2.5341 1.9627
KYSE-270 GDSC1; GDSC2 4.9924 8.7354 1.8483 5.4266
T.T GDSC1; GDSC2 4.9949 7.9749 2.1975 3.4763
TE-15 GDSC1; GDSC2 5.0779 8.0951 2.1911 3.3819
OE19 GDSC1; GDSC2 5.1727 6.4502 2.907 0.237
EC-GI-10 GDSC1; GDSC2 5.3264 7.1185 2.7224 0.6725
TE-11 GDSC1; GDSC2 5.4498 8.582 2.182 2.8972
OE33 GDSC1; GDSC2 5.4792 7.153 2.7718 0.4375
COLO 680N GDSC1; GDSC2 5.5027 10.0714 1.545 6.2069
TE-4 GDSC1; GDSC2 5.5069 7.6384 2.5998 0.9734
KYSE-140 GDSC1; GDSC2 5.5374 11.939 0.6905 10.7699
TE-9 GDSC1; GDSC2 5.6303 7.1886 2.8168 0.2694
TE-5 GDSC1; GDSC2 5.8589 7.4522 2.8084 0.2168
TE-8 GDSC1; GDSC2 6.0545 8.1555 2.6321 0.5355
OE21 GDSC1; GDSC2 6.0596 14.1369 -0.0093 13.1877
TE-6 GDSC1; GDSC2 6.0872 7.9325 2.7244 0.3074
KYSE-410 GDSC1; GDSC2 6.1381 8.3537 2.5926 0.6015
TE-10 GDSC1; GDSC2 6.2142 7.9375 2.7685 0.1946
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVTOKO GDSC1; GDSC2 2.7627 8.5852 0.2109 20.6328
OAW28 GDSC1; GDSC2 3.3513 6.4908 1.7619 9.779
OAW42 GDSC1; GDSC2 4.1597 5.2301 2.9425 0.8056
DOV13 GDSC1; GDSC2 4.2523 6.5291 2.4116 3.5535
JHOS-4 GDSC1; GDSC2 4.3064 7.2777 2.0922 5.3421
A2780 GDSC1; GDSC2 4.4317 6.9587 2.3242 3.7248
OVK18 GDSC1; GDSC2 4.7034 8.9484 1.5601 7.666
FU-OV-1 GDSC1; GDSC2 4.7691 6.6871 2.6374 1.5278
ES-2 GDSC1; GDSC2 4.7872 6.5308 2.7116 1.1667
OVKATE GDSC1; GDSC2 4.8545 7.9623 2.1204 4.1332
TOV-21G GDSC1; GDSC2 4.9115 9.5135 1.4297 7.9868
OC 314 GDSC1; GDSC2 4.935 6.8926 2.6343 1.3544
TOV-112D GDSC1; GDSC2 5.0186 10.0044 1.2669 8.6934
SK-OV-3 GDSC1; GDSC2 5.2623 12.1796 0.3874 12.9277
OVISE GDSC1; GDSC2 5.2847 11.9863 0.4963 12.318
OVCAR-4 GDSC1; GDSC2 5.2871 8.2973 2.2181 2.9358
JHOS-2 GDSC1; GDSC2 5.4016 11.5498 0.7854 10.5479
EFO-27 GDSC1; GDSC2 5.4477 7.5892 2.5928 1.0463
Kuramochi GDSC1; GDSC2 5.4963 7.3858 2.6922 0.6623
OVCAR-3 GDSC1; GDSC2 5.6319 7.4185 2.7349 0.4629
EFO-21 GDSC1; GDSC2 5.6573 7.5066 2.7127 0.5109
OV-90 GDSC1; GDSC2 5.7749 7.5927 2.7274 0.4174
IGROV-1 GDSC1; GDSC2 5.9296 7.9686 2.6512 0.5444
RMG-I GDSC1; GDSC2 5.9391 8.3373 2.5169 0.953
TYK-nu GDSC1; GDSC2 5.991 11.2802 1.2857 6.7619
OVCAR-5 GDSC1; GDSC2 6.1244 13.5292 0.3222 11.466
Caov-4 GDSC1; GDSC2 6.1466 8.0575 2.7024 0.3327
Caov-3 GDSC2 6.198 15.8115 -0.7189 16.0597
OVCAR-8 GDSC1; GDSC2 6.4889 8.1172 2.8031 0.1029
OV56 GDSC1; GDSC2 8.4891 23.3628 -2.7884 19.0892
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1990 GDSC1; GDSC2 3.8511 5.5323 2.6206 3.117
Capan-1 GDSC1; GDSC2 3.9484 5.7555 2.5793 3.1618
QGP-1 GDSC1; GDSC2 4.3621 6.5292 2.4799 2.9578
HPAF-II GDSC1; GDSC2 4.4453 7.2364 2.203 4.4046
KP-4 GDSC1; GDSC2 4.5859 11.0868 0.4359 14.2501
KP-1N GDSC1; GDSC2 4.6522 7.9199 2.0145 5.1076
KP-3 GDSC1; GDSC2 4.6689 9.0991 1.4642 8.301
SU.86.86 GDSC1; GDSC2 4.717 6.1499 2.8326 0.7284
MIA PaCa-2 GDSC1; GDSC2 4.8062 7.2929 2.3944 2.7089
HPAC GDSC1; GDSC2 4.8273 7.0728 2.5026 2.1166
HuP-T3 GDSC1; GDSC2 4.8381 7.1555 2.4725 2.2553
DAN-G GDSC1; GDSC2 4.8696 10.5442 0.9052 11.0463
HuP-T4 GDSC1; GDSC2 4.9829 6.9886 2.6181 1.376
KP-2 GDSC1; GDSC2 5.0951 13.5264 -0.3886 17.047
PaTu 8988t GDSC1; GDSC2 5.1414 6.7134 2.7984 0.5434
YAPC GDSC1; GDSC2 5.2069 6.3087 2.9686 0.1159
Panc 03.27 GDSC1; GDSC2 5.2838 8.222 2.2491 2.7828
Panc 02.03 GDSC1; GDSC2 5.2914 8.2964 2.2208 2.9159
SUIT-2 GDSC1; GDSC2 5.3757 8.6416 2.1158 3.3374
PL4 GDSC1; GDSC2 5.4082 7.335 2.6744 0.7797
PSN1 GDSC1; GDSC2 5.4084 9.6276 1.6916 5.5658
PaTu 8902 GDSC1; GDSC2 5.5103 6.8937 2.8758 0.1925
Capan-2 GDSC1; GDSC2 5.5313 8.159 2.4023 1.7563
Panc 04.03 GDSC1; GDSC2 5.6235 7.2854 2.7798 0.3537
Panc 08.13 GDSC1; GDSC2 5.8852 7.8632 2.6722 0.5092
MZ-PC-1 GDSC1; GDSC2 6.0683 8.2071 2.6187 0.5648
AsPC-1 GDSC1; GDSC2 6.0785 8.3064 2.5862 0.6501
CFPAC-1 GDSC1; GDSC2 6.1212 14.0841 0.0569 12.7517
Panc 10.05 GDSC1; GDSC2 6.1842 7.8435 2.79 0.1693
BxPC-3 GDSC1; GDSC2 6.1913 8.3197 2.6258 0.4901
Hs 766T GDSC1; GDSC2 8.1185 16.3516 0.237 8.4993
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1; GDSC2 4.2167 6.565 2.3717 3.8575
IST-Mes1 GDSC1; GDSC2 5.1252 6.8158 2.7525 0.7076
NCI-H2452 GDSC1; GDSC2 5.6099 7.3803 2.7402 0.4593
NCI-H2052 GDSC1; GDSC2 6.0431 7.5296 2.847 0.1205
MSTO-211H GDSC1; GDSC2 6.0549 8.8921 2.3514 1.4731
NCI-H28 GDSC1; GDSC2 6.3124 7.9826 2.7876 0.1478
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 GDSC1; GDSC2 4.0932 6.0275 2.5452 3.0755
PC-3 GDSC1; GDSC2 4.1419 6.4384 2.3826 3.9426
VCaP GDSC1; GDSC2 4.749 6.7659 2.5935 1.7654
NCI-H660 GDSC2 4.8586 6.3831 2.8041 0.7215
LNCaP clone FGC GDSC1; GDSC2 5.1073 7.8698 2.307 2.7305
22Rv1 GDSC1; GDSC2 5.9762 8.2169 2.578 0.7312
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 4.816 7.1693 2.4544 2.3796
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 800 GDSC1; GDSC2 3.9395 5.9665 2.4722 3.8273
UACC-257 GDSC1; GDSC2 4.0362 5.3465 2.8247 1.5787
VMRC-MELG GDSC2 4.101 6.5001 2.3259 4.3683
RPMI-7951 GDSC1; GDSC2 4.1569 6.5014 2.3627 4.0313
CHL-1 GDSC1; GDSC2 4.3433 7.0285 2.235 4.4154
GAK GDSC1; GDSC2 4.3591 6.6567 2.4193 3.3098
A-431 GDSC1; GDSC2 4.3907 6.2188 2.6374 2.0398
SK-MEL-2 GDSC1; GDSC2 4.5376 8.7276 1.5529 8.0664
IGR-37 GDSC1; GDSC2 4.5397 6.8751 2.4284 2.9446
A-388 GDSC1; GDSC2 4.5936 7.1917 2.3161 3.482
CP50-MEL-B GDSC1; GDSC2 4.6201 6.5534 2.6168 1.8185
SK-MEL-5 GDSC1; GDSC2 4.627 6.5441 2.6245 1.7703
MeWo GDSC1; GDSC2 4.6612 7.1492 2.3756 3.0368
Hs 940.T GDSC1; GDSC2 4.6873 15.0066 -1.4252 22.2694
SK-MEL-28 GDSC1; GDSC2 4.7045 5.5415 3.0529 0.1001
MZ-MEL-7 GDSC1; GDSC2 4.7677 6.3509 2.7756 0.9123
IST-MEL1 GDSC1; GDSC2 4.8399 6.7107 2.663 1.3279
A2058 GDSC1; GDSC2 4.8565 6.0185 2.941 0.2838
COLO 783 GDSC1; GDSC2 4.9025 7.1231 2.5208 1.9273
SK-MEL-3 GDSC1; GDSC2 4.9234 6.028 2.9632 0.2045
SH-4 GDSC1; GDSC2 4.9512 6.8561 2.6572 1.2363
SK-MEL-31 GDSC1; GDSC2 4.9764 6.8812 2.659 1.2029
A101D GDSC1; GDSC2 4.9996 6.4272 2.8475 0.4751
A-375 GDSC1; GDSC2 5.0081 11.4515 0.5623 12.5886
Hs 938.T GDSC1; GDSC2 5.0263 10.5922 0.9904 10.228
WT2-iPS GDSC1; GDSC2 5.0271 7.2679 2.5235 1.7617
451Lu GDSC1; GDSC2 5.0322 7.4825 2.4347 2.1862
SK-MEL-30 GDSC1; GDSC2 5.1088 6.2356 2.9587 0.1554
G-mel GDSC1; GDSC2 5.1169 16.6307 -1.9022 22.9123
COLO 829 GDSC1; GDSC2 5.1235 7.0526 2.6587 1.0649
HT-144 GDSC1; GDSC2 5.1315 8.9003 1.8577 5.1245
WM278 GDSC1; GDSC2 5.1443 7.3377 2.5527 1.4963
LB373-MEL-D GDSC1; GDSC2 5.1544 6.7658 2.7841 0.5813
COLO 792 GDSC1; GDSC2 5.1711 7.0043 2.6993 0.8662
Mel Ho GDSC1; GDSC2 5.1734 6.4728 2.8992 0.2538
CP66-MEL GDSC1; GDSC2 5.1774 6.3165 2.9554 0.1431
IPC-298 GDSC1; GDSC2 5.1954 6.6143 2.8568 0.3468
WM115 GDSC1; GDSC2 5.1967 6.6213 2.8548 0.3514
UACC-62 GDSC1; GDSC2 5.2578 6.742 2.8347 0.3754
Mel JuSo GDSC1; GDSC2 5.2599 7.2536 2.6409 1.0169
MZ-MEL-2 GDSC1; GDSC2 5.2963 12.1736 0.414 12.7168
WM1552C GDSC1; GDSC2 5.3629 7.0781 2.7528 0.5533
LB2518-MEL GDSC1; GDSC2 5.4099 6.8011 2.8714 0.2307
RVH-421 GDSC1; GDSC2 5.4164 6.6695 2.9194 0.1436
G-361 GDSC1; GDSC2 5.4193 6.8239 2.8669 0.2367
M14 GDSC1 5.5006 7.2138 2.758 0.5786
LOX-IMVI GDSC1; GDSC2 5.5136 7.0444 2.8242 0.2945
COLO 679 GDSC1; GDSC2 5.5216 6.8263 2.9031 0.1449
IGR-1 GDSC1; GDSC2 5.5283 6.9522 2.8621 0.2125
WM793 GDSC1; GDSC2 5.5965 7.2238 2.7916 0.3368
SK-MEL-24 GDSC1; GDSC2 5.6491 7.1775 2.8276 0.2417
DJM-1 GDSC1; GDSC2 5.6645 7.7579 2.6216 0.7848
WM35 GDSC1; GDSC2 5.7175 9.8088 1.7904 4.533
SK-MEL-1 GDSC1; GDSC2 6.1866 14.5289 -0.1116 13.4085
HMV-II GDSC1; GDSC2 6.3067 8.6292 2.5583 0.6119
MMAc-SF GDSC1; GDSC2 6.5445 15.2125 -0.1999 13.1106
EquiPSC Line K2 GDSC1; GDSC2 6.0303 8.4673 2.5059 0.9283
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 4.7743 6.3811 2.7665 0.9439
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW872 GDSC1; GDSC2 3.9057 5.6512 2.6005 3.1232
STS-0421 GDSC1; GDSC2 4.0201 7.3211 1.8702 7.3375
MES-SA GDSC1; GDSC2 4.4292 5.8399 2.8221 1.0569
TE 441.T GDSC2 4.6149 6.0703 2.8174 0.8825
SK-UT-1 GDSC1; GDSC2 4.7076 6.3136 2.7624 1.0263
Rh30 GDSC1; GDSC2 4.7147 6.4996 2.6888 1.3495
MFH-ino GDSC1; GDSC2 4.7307 8.0911 1.9843 5.1335
Hs 633.T GDSC1; GDSC2 4.7722 9.3587 1.4099 8.3939
SW982 GDSC1; GDSC2 4.8555 6.7368 2.6599 1.3254
EW-8 GDSC1; GDSC2 4.9092 6.5045 2.779 0.7757
SW684 GDSC1; GDSC2 4.9292 6.6024 2.7493 0.874
GCT GDSC1; GDSC2 4.9371 7.8736 2.2096 3.5021
Rh41 GDSC1; GDSC2 4.9443 6.8527 2.6553 1.2518
SK-LMS-1 GDSC1; GDSC2 5.0828 9.6058 1.4984 7.2484
KYM-1 GDSC1; GDSC2 5.1715 6.8568 2.7566 0.6612
HT-1080 GDSC1; GDSC2 5.2486 6.5403 2.9035 0.2184
A-204 GDSC1; GDSC2 5.4696 10.2081 1.4616 6.725
VA-ES-BJ GDSC1; GDSC2 5.6776 11.2568 1.1038 8.2925
RKN GDSC1; GDSC2 5.8502 6.9857 2.9618 0.0388
RD GDSC1; GDSC2 6.0576 7.859 2.7392 0.2874
G-401 GDSC1; GDSC2 6.078 8.2736 2.5981 0.6166
G-402 GDSC1; GDSC2 6.4894 8.9857 2.5 0.6808
Rh18 GDSC1 6.6469 12.9542 0.9136 9.1113
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC12 GDSC2 4.0301 5.573 2.7176 2.1913
23132/87 GDSC1; GDSC2 4.0806 5.9658 2.5662 2.9767
SCH GDSC1; GDSC2 4.1749 5.8434 2.6812 2.1457
MKN1 GDSC1; GDSC2 4.648 7.008 2.4315 2.7524
MKN7 GDSC1; GDSC2 4.7263 8.2172 1.9223 5.5015
SNU-16 GDSC1; GDSC2 4.7292 6.6677 2.6251 1.6355
MKN45 GDSC1; GDSC2 4.7711 6.0496 2.895 0.4648
AGS GDSC1; GDSC2 4.9771 6.3473 2.8681 0.4255
SNU-5 GDSC1; GDSC2 5.0401 6.4125 2.8693 0.3881
HSC-39 GDSC1; GDSC2 5.0777 6.5841 2.8207 0.5119
NUGC-3 GDSC1; GDSC2 5.0831 7.6 2.411 2.2375
GCIY GDSC1; GDSC2 5.2025 7.2472 2.6172 1.1624
IM95 GDSC1; GDSC2 5.2668 8.3424 2.1873 3.1227
ECC10 GDSC1; GDSC2 5.2913 8.7083 2.0389 3.8679
TGBC11TKB GDSC1; GDSC2 5.2924 7.082 2.7219 0.6967
SNU-1 GDSC1; GDSC2 5.2958 10.0207 1.4399 7.1671
MKN28 GDSC1; GDSC2 5.2994 7.4924 2.5636 1.2937
TMK-1 GDSC1; GDSC2 5.3374 7.6194 2.53 1.3984
HGC-27 GDSC1; GDSC2 5.5451 7.1939 2.7827 0.3794
Fu97 GDSC1; GDSC2 5.5614 8.281 2.3666 1.8831
NUGC-4 GDSC1; GDSC2 5.619 7.1821 2.8149 0.2772
SK-GT-2 GDSC1; GDSC2 5.7103 9.3891 1.9715 3.6058
OCUM-1 GDSC1; GDSC2 5.7362 7.7835 2.6418 0.6758
RF-48 GDSC1; GDSC2 5.7711 7.7204 2.6793 0.5461
NCI-N87 GDSC1; GDSC2 5.8419 7.8724 2.6516 0.5877
Hs 746.T GDSC1; GDSC2 5.8726 11.6809 1.0287 8.3315
KATO III GDSC1; GDSC2 5.8735 7.6835 2.7325 0.3652
RERF-GC-1B GDSC1; GDSC2 7.1659 9.4674 2.5826 0.2645
SNG-M GDSC1; GDSC2 5.3342 10.452 1.262 8.0847
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HTC-C3 GDSC1; GDSC2 4.0707 6.2186 2.44 3.7453
WRO GDSC1; GDSC2 4.3108 5.8722 2.7461 1.5835
KMH-2 GDSC1; GDSC2 4.5305 7.1011 2.3193 3.5743
IHH-4 GDSC1; GDSC2 4.5329 6.0447 2.7882 1.0961
B-CPAP GDSC1; GDSC2 4.5544 7.5032 2.1475 4.5201
TT GDSC1; GDSC2 4.6898 6.4721 2.6878 1.3833
ML-1 [Human leukemia] GDSC1; GDSC2 4.7357 8.3415 1.8699 5.7878
BHT-101 GDSC1; GDSC2 4.8632 14.5147 -1.0476 20.3962
CGTH-W-1 GDSC1; GDSC2 5.1371 7.7653 2.3684 2.3788
CAL-62 GDSC1; GDSC2 5.1412 6.6631 2.8172 0.4853
ASH-3 GDSC1; GDSC2 5.1647 6.6652 2.8259 0.4465
FTC-133 GDSC1; GDSC2 5.5145 10.5065 1.351 7.2515
8305C GDSC1; GDSC2 5.5173 7.74 2.5646 1.0973
K5 GDSC1; GDSC2 6.0783 7.8726 2.742 0.2756
8505C GDSC1; GDSC2 8.1052 16.4507 0.1852 8.7464
TT2609-C02 GDSC1; GDSC2 8.1285 15.3871 0.6675 6.5775
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 31 GDSC2 2.9938 4.3659 2.5064 6.204
PCI-15A GDSC1; GDSC2 3.3671 6.567 1.7369 9.8899
PCI-38 GDSC1 4.0363 9.3793 0.866 16.0982
CAL-27 GDSC1; GDSC2 4.1323 6.1839 2.4968 3.2846
SCC-4 GDSC1; GDSC2 4.1575 6.503 2.3622 4.0328
FaDu GDSC1; GDSC2 4.239 6.2554 2.5308 2.8867
HSC-4 GDSC2 4.38 6.6454 2.4373 3.1689
SCC-15 GDSC1; GDSC2 4.6527 9.7565 1.1349 10.2441
OSC-20 GDSC1; GDSC2 4.6661 6.621 2.6121 1.7806
DOK GDSC1; GDSC2 4.8803 7.4852 2.3508 2.8298
HSC-2 GDSC1; GDSC2 4.8939 6.2808 2.8588 0.5042
PE/CA-PJ15 GDSC1; GDSC2 5.009 8.5841 1.9286 4.9424
LB771-HNC GDSC1; GDSC2 5.1374 7.1596 2.6221 1.2028
Detroit 562 GDSC1; GDSC2 5.2532 7.8805 2.3798 2.1758
SAT [Human HNSCC] GDSC1; GDSC2 5.2635 12.0561 0.448 12.6142
BHY GDSC1; GDSC2 5.3003 11.2393 0.8659 10.327
HO-1-N-1 GDSC1; GDSC2 5.32 7.1297 2.7154 0.7
KOSC-2 GDSC1; GDSC2 5.3472 12.6361 0.2256 13.5554
SKN-3 GDSC1; GDSC2 5.3639 12.5503 0.2788 13.2534
HSC-3 GDSC1; GDSC2 5.3923 7.1937 2.7215 0.6335
Ca9-22 GDSC1; GDSC2 5.4852 7.4001 2.6822 0.7018
UPCI-SCC-090 GDSC1; GDSC2 5.5185 7.7778 2.5502 1.1518
CAL-33 GDSC1; GDSC2 5.5757 7.8543 2.5457 1.1216
BB30-HNC GDSC1; GDSC2 5.6154 11.6723 0.8685 9.672
JHU-029 GDSC1; GDSC2 5.8823 8.904 2.2658 1.9918
HO-1-u-1 GDSC1; GDSC2 5.891 7.6004 2.7685 0.2822
SCC-25 GDSC1; GDSC2 5.8964 7.8429 2.684 0.4733
NCI-H3118 GDSC1; GDSC2 6.0905 9.2523 2.2231 1.9663
SCC-9 GDSC1; GDSC2 6.1436 7.832 2.7796 0.1936
PCI-30 GDSC1; GDSC2 6.1616 8.3719 2.5952 0.5828
SAS GDSC1; GDSC2 6.1803 11.3619 1.3602 6.062
BB49-HNC GDSC1 6.1809 8.237 2.6515 0.5385
PCI-06A GDSC1; GDSC2 6.2651 13.7186 0.324 11.1866
JHU-011 GDSC1; GDSC2 6.5677 15.2222 -0.1894 13.0186
OSC-19 GDSC1; GDSC2 6.8885 17.3872 -1.0064 15.8611
BICR 10 GDSC1 7.0393 16.3542 -0.4179 15.1963
BICR 78 GDSC1; GDSC2 7.2985 17.4551 -0.769 14.1463
PCI-04B GDSC1; GDSC2 7.9289 17.9427 -0.599 12.3622
JHU-022 GDSC1; GDSC2 8.1285 19.934 -1.4015 15.1351
BICR 22 GDSC1; GDSC2 8.4675 19.2199 -0.8581 12.5266
KON GDSC1; GDSC2 8.5248 24.2831 -3.2039 20.2173
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC1; GDSC2 4.2239 5.4926 2.8641 1.1032
CAL-29 GDSC1; GDSC2 4.2623 8.0956 1.6661 8.0116
SW1710 GDSC1; GDSC2 4.2959 6.2948 2.5474 2.6912
BFTC-905 GDSC1; GDSC2 4.3877 7.1022 2.2291 4.363
SW780 GDSC1; GDSC2 4.6009 6.7 2.5421 2.2321
T24 GDSC1; GDSC2 4.6383 6.5155 2.6428 1.6643
5637 GDSC1; GDSC2 4.7161 6.6417 2.6294 1.6309
639V GDSC1; GDSC2 4.7922 10.4229 0.9096 11.1971
J82 GDSC1; GDSC2 5.094 7.2464 2.5658 1.4914
HT-1197 GDSC1; GDSC2 5.1549 7.9682 2.2899 2.7517
UM-UC-3 GDSC1; GDSC2 5.1997 7.2225 2.6258 1.1295
RT-4 GDSC1; GDSC2 5.3198 7.5625 2.5448 1.353
647V GDSC1; GDSC2 5.3685 6.5627 2.9389 0.1249
RT-112 GDSC1; GDSC2 5.3786 9.6569 1.6601 5.7911
HT-1376 GDSC1; GDSC2 5.3964 7.7932 2.4873 1.523
TCCSUP GDSC1; GDSC2 5.8151 7.0831 2.9181 0.0765
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NT2-D1 GDSC1; GDSC2 3.7975 5.2596 2.715 2.6601
HeLa GDSC1; GDSC2 4.0764 5.1948 2.9144 1.0453
SW954 GDSC1; GDSC2 4.3939 7.791 1.9053 6.2777
C-33 A GDSC1; GDSC2 4.4681 6.7521 2.4418 2.9901
SiHa GDSC1; GDSC2 4.5699 8.2829 1.7886 6.6012
HT-3 GDSC1; GDSC2 4.5858 6.9893 2.4037 3.0051
DSH1 GDSC1; GDSC2 4.5943 6.6441 2.563 2.1315
DoTc2 4510 GDSC1; GDSC2 4.5968 6.7227 2.5297 2.3033
HEY GDSC1; GDSC2 4.6762 7.0694 2.4202 2.7695
LB831-BLC GDSC1; GDSC2 4.6782 6.8277 2.5286 2.1905
OVCA433 GDSC1; GDSC2 4.9454 7.0933 2.5556 1.7062
SKN GDSC1; GDSC2 4.9754 9.3986 1.5264 7.3014
JHOS-3 GDSC1; GDSC2 5.0062 7.4852 2.4197 2.2949
BPH-1 GDSC1; GDSC2 5.028 8.7214 1.8769 5.2003
KGN GDSC1; GDSC2 5.0541 7.2708 2.5359 1.6722
ME-180 GDSC1; GDSC2 5.0817 7.4819 2.4608 1.9956
PEO1 GDSC1; GDSC2 5.0911 11.2793 0.7037 11.6501
SKG-IIIa GDSC1; GDSC2 5.1586 6.5641 2.8607 0.3536
PA-1 GDSC1; GDSC2 5.2106 6.6497 2.8499 0.3577
C-4-I GDSC1; GDSC2 5.2223 6.8773 2.7702 0.5832
NCC-IT GDSC2 5.2418 6.9545 2.7491 0.6395
OVMIU GDSC1; GDSC2 5.2892 13.6837 -0.325 16.3094
NEC8 GDSC1; GDSC2 5.3173 14.5032 -0.7055 17.9171
MS751 GDSC1; GDSC2 5.3628 7.0101 2.778 0.4789
JEG-3 GDSC1; GDSC2 5.383 7.3199 2.6694 0.8149
SiSo GDSC1; GDSC2 5.4028 7.3319 2.6733 0.7873
TC-YIK GDSC1; GDSC2 5.4732 7.6527 2.5792 1.0775
SW962 GDSC1; GDSC2 5.5088 7.3952 2.6939 0.6495
CAL-39 GDSC1; GDSC2 5.5472 7.3877 2.7124 0.5703
JAR GDSC1; GDSC2 5.5814 7.1208 2.8225 0.2741
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 5.6765 7.407 2.7564 0.3879
PWR-1E GDSC1; GDSC2 5.6982 8.0451 2.5253 1.1001
HEC-1 GDSC1; GDSC2 5.8878 7.2975 2.8713 0.117
SW756 GDSC1; GDSC2 6.0776 15.4937 -0.6486 16.0125
OVCA420 GDSC1; GDSC2 6.0964 7.8479 2.7572 0.2426
UWB1.289 GDSC1; GDSC2 6.2448 13.8319 0.2575 11.5484
Ca Ski GDSC1; GDSC2 6.2473 9.4062 2.2344 1.7704
OV17R GDSC1; GDSC2 7.0966 15.2787 0.1199 10.6476
ACC-OV7 GDSC1; GDSC2 7.6475 18.3291 -0.9558 14.2738
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity. J Med Chem. 2006 Jun 15;49(12):3563-80.