General Information of Drug (ID: DM9SKW8)

Drug Name
Capivasertib
Synonyms
AZD5363; 1143532-39-1; AZD-5363; capivasertib; AZD 5363; UNII-WFR23M21IE; WFR23M21IE; cc-638; 4-Amino-N-[(1s)-1-(4-Chlorophenyl)-3-Hydroxypropyl]-1-(7h-Pyrrolo[2,3-D]pyrimidin-4-Yl)piperidine-4-Carboxamide; C21H25ClN6O2; (S)-4-AMINO-N-(1-(4-CHLOROPHENYL)-3-HYDROXYPROPYL)-1-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE; 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinecarboxamide; 4-Piperidinecarboxamide, 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Approved [1]
Triple negative breast cancer 2C60-2C65 Phase 3 [2]
Solid tumour/cancer 2A00-2F9Z Phase 2 [3]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 428.9
Logarithm of the Partition Coefficient (xlogp) 1.7
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 4
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C21H25ClN6O2
IUPAC Name
4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Canonical SMILES
C1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4
InChI
InChI=1S/C21H25ClN6O2/c22-15-3-1-14(2-4-15)17(6-12-29)27-20(30)21(23)7-10-28(11-8-21)19-16-5-9-24-18(16)25-13-26-19/h1-5,9,13,17,29H,6-8,10-12,23H2,(H,27,30)(H,24,25,26)/t17-/m0/s1
InChIKey
JDUBGYFRJFOXQC-KRWDZBQOSA-N
Cross-matching ID
PubChem CID
25227436
CAS Number
1143532-39-1
UNII
WFR23M21IE
DrugBank ID
DB12218
TTD ID
D01ZAQ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
RAC-alpha serine/threonine-protein kinase (AKT1) TTWTSCV AKT1_HUMAN Inhibitor [4]
RAC-gamma serine/threonine-protein kinase (AKT3) TTAZ05C AKT3_HUMAN Modulator [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) OTUYHB84 MLP3B_HUMAN Gene/Protein Processing [6]
Proline-rich AKT1 substrate 1 (AKT1S1) OT4JHN4Y AKTS1_HUMAN Post-Translational Modifications [6]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Post-Translational Modifications [6]
Sequestosome-1 (SQSTM1) OTGY5D5J SQSTM_HUMAN Gene/Protein Processing [6]
Small ribosomal subunit protein eS6 (RPS6) OTT4D1LN RS6_HUMAN Post-Translational Modifications [6]
Sterol regulatory element-binding protein 1 (SREBF1) OTWBRPAI SRBP1_HUMAN Gene/Protein Processing [6]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Breast cancer
ICD Disease Classification 2C60-2C65
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
RAC-alpha serine/threonine-protein kinase (AKT1) DTT AKT1 2.63E-29 0.65 1.45
RAC-gamma serine/threonine-protein kinase (AKT3) DTT AKT3 6.79E-01 -0.02 -0.08
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.1985 7.5286 1.9962 29.0065
RPMI-3460/CS1 GDSC2 4.0018 10.197 0.4333 15.7643
EW-18 GDSC1 -1.4903 4.2699 -1.9115 68.4982
EW-12 GDSC2 1.2129 6.845 -0.4031 29.3567
CHSA0108 GDSC2 1.3375 7.0335 -0.3673 28.679
CHSA0011 GDSC2 1.6481 7.7303 -0.3958 27.5481
ES5 GDSC2 1.8072 9.2036 -0.9603 29.2248
HOS GDSC1 1.9451 7.2385 0.8356 41.2412
MG-63 GDSC1 2.0103 8.8902 0.182 42.2751
SK-PN-DW GDSC2 2.0175 7.3418 0.143 23.5985
HuO9 GDSC1 2.0691 11.447 -0.95 43.6822
H-EMC-SS GDSC1 2.0952 7.6815 0.8039 40.3483
EW-7 GDSC2 2.1465 6.4986 0.6724 20.304
EW-11 GDSC2 2.1817 11.0821 -1.5451 29.9394
SK-ES-1 GDSC1 2.2042 11.9353 -1.053 43.1772
EW-13 GDSC1 2.3371 7.6269 1.0769 38.0176
SK-ES-1 GDSC2 2.4008 5.6391 1.3281 15.5525
U2OS GDSC1 2.4672 6.5199 1.6793 34.8378
ES1 GDSC2 2.5825 9.4683 -0.3873 24.1131
ES1 GDSC1 2.6051 9.3915 0.5437 38.1025
EW-22 GDSC2 2.6527 7.0594 0.8699 17.3926
EW-3 GDSC2 2.6623 7.5263 0.6476 18.6239
EW-11 GDSC1 2.8305 7.4607 1.6554 32.772
ES5 GDSC1 2.9344 7.4187 1.7797 31.5829
EW-3 GDSC1 3.1028 7.8189 1.7673 30.7198
CHSA0108 GDSC1 3.1157 10.2729 0.6162 35.2946
H-EMC-SS GDSC2 3.1489 10.2956 -0.3101 21.9343
EW-18 GDSC2 3.4193 9.7402 0.1936 18.6649
ES7 GDSC1 3.48 7.4981 2.2903 25.8406
EW-7 GDSC1 3.5686 7.8347 2.2191 25.8272
ES6 GDSC2 3.585 9.7086 0.3451 17.393
EW-1 GDSC2 3.6315 11.7321 -0.628 21.9114
G-292 clone A141B1 GDSC1 3.6385 10.4753 1.006 31.4577
SJSA-1 GDSC2 3.6424 10.6601 -0.0836 19.3932
EW-13 GDSC2 3.6758 8.5344 1.0044 13.4689
EW-24 GDSC2 3.7178 10.3385 0.1379 18.0822
HuO-3N1 GDSC2 3.7371 7.8574 1.3902 11.0017
ES8 GDSC1 3.7745 7.3923 2.6287 22.2221
A-673 GDSC2 3.8155 6.3816 2.1814 5.9052
ES8 GDSC2 3.8469 7.5214 1.642 9.173
CAL-72 GDSC2 3.9496 7.6692 1.6467 8.8835
TC-71 GDSC2 3.9932 7.1505 1.9341 7.0084
CADO-ES1 GDSC2 4.0432 6.8121 2.1353 5.6548
ES4 GDSC1 4.077 10.8559 1.2153 28.6645
HuO-3N1 GDSC1 4.2422 8.8329 2.3657 21.8171
HuO9 GDSC2 4.3041 13.7374 -1.0916 21.9764
CHSA8926 GDSC2 4.331 9.2392 1.1563 10.8775
ES7 GDSC2 4.3549 8.1554 1.7026 7.5807
SaOS-2 GDSC2 4.3594 9.7662 0.9182 12.1747
CHSA0011 GDSC1 4.3738 10.2263 1.7908 24.6174
MG-63 GDSC2 4.3924 14.4524 -1.3783 22.8386
SJSA-1 GDSC1 4.3968 8.044 2.8953 17.5879
NY GDSC2 4.4683 8.5405 1.5952 7.969
EW-22 GDSC1 4.5194 7.9585 3.0473 15.9816
HOS GDSC2 4.6468 8.9711 1.5107 8.0763
A-673 GDSC1 4.6509 6.8116 3.7336 10.2197
ES4 GDSC2 4.6911 9.3813 1.3434 8.9559
EW-16 GDSC2 4.7993 11.1326 0.5689 13.0354
ES6 GDSC1 4.8544 9.2614 2.6857 17.2365
MHH-ES-1 GDSC1 4.8783 8.2817 3.1957 13.4872
U2OS GDSC2 4.9855 11.6364 0.4564 13.1954
SaOS-2 GDSC1 4.9982 11.9946 1.4388 24.0044
EW-24 GDSC1 5.0349 7.0919 3.9191 7.3371
G-292 clone A141B1 GDSC2 5.0917 14.5709 -0.9044 19.2712
EW-16 GDSC1 5.1389 11.7863 1.6585 22.3807
NOS-1 [Human HNSCC] GDSC2 5.1719 11.8286 0.4943 12.5772
NY GDSC1 5.2497 8.0606 3.6059 9.0609
MHH-ES-1 GDSC2 5.2578 10.5231 1.1787 8.6988
CAL-78 GDSC2 5.3572 7.038 2.7654 0.5187
TC-71 GDSC1 5.4827 8.2924 3.6667 7.8633
U-CH2 GDSC2 5.5504 7.6031 2.6323 0.8255
CAL-72 GDSC1 5.8345 9.7951 3.1861 10.3999
EW-1 GDSC1 6.0595 8.2491 4.0706 3.4055
NOS-1 [Human HNSCC] GDSC1 6.0619 14.0753 1.2461 21.3886
CADO-ES1 GDSC1 6.3638 8.4452 4.1537 2.3035
CAL-78 GDSC1 6.6113 9.8671 3.6621 5.0677
CHSA8926 GDSC1 6.7512 12.8958 2.3254 13.5508
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 318 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 5.2541 8.8344 1.9608 4.3483
JM1 GDSC1 5.658 9.0439 3.4261 9.1577
MOLT-16 GDSC1 -4.0232 1.7167 -4.189 83.717
NCI-H929 GDSC1 -3.947 -0.3435 -3.9618 90.5325
WSU-DLCL2 GDSC1 -3.0763 -1.3566 -3.0764 93.1133
Jurkat GDSC2 -3.0372 0.6857 -3.1149 62.2962
WSU-DLCL2 GDSC2 -2.9355 -0.8002 -2.9386 62.5965
SU-DHL-6 GDSC1 -2.623 -0.1174 -2.6261 86.9
Loucy GDSC1 -2.4374 0.6263 -2.4517 83.4331
KE-37 GDSC2 -2.3572 3.5006 -2.9256 55.1081
MM1.S GDSC1 -2.3482 0.4596 -2.3569 83.6579
NCI-H929 GDSC2 -2.2238 -0.0443 -2.2312 55.5741
KE-37 GDSC1 -2.0958 1.0403 -2.1167 80.4642
MM1.S GDSC2 -2.019 0.4336 -2.0375 53.5137
OCI-Ly7 GDSC1 -1.9844 -0.6682 -1.9845 85.049
SU-DHL-16 GDSC2 -1.9837 -0.0752 -1.9875 53.2211
CCRF-CEM GDSC1 -1.9391 3.0259 -2.1476 73.6313
DoHH2 GDSC2 -1.8606 -0.2348 -1.862 52.0026
L-363 GDSC1 -1.522 2.4834 -1.6262 72.9932
SU-DHL-5 GDSC2 -1.4679 0.6571 -1.4815 48.089
SU-DHL-5 GDSC1 -1.3516 2.4084 -1.4378 72.1765
WSU-NHL GDSC1 -1.2853 1.7784 -1.3177 73.3927
TUR GDSC1 -1.2572 2.4814 -1.3457 71.3876
SU-DHL-6 GDSC2 -1.2372 0.5094 -1.2423 45.7678
SU-DHL-4 GDSC1 -1.1071 0.2889 -1.1072 74.8343
MOLT-4 GDSC1 -1.0824 3.3503 -1.2797 68.2073
SU-DHL-10 GDSC1 -1.0757 0.2648 -1.0758 74.5088
NU-DUL-1 GDSC1 -1.0627 4.3768 -1.4712 65.9864
SUP-B8 GDSC2 -0.9352 3.5364 -1.3843 43.8985
SU-DHL-16 GDSC1 -0.8854 0.1041 -0.8854 72.3626
HT GDSC2 -0.8624 6.5694 -2.4105 44.9913
Kasumi-1 GDSC1 -0.8491 1.9902 -0.8788 69.5162
Karpas-620 GDSC1 -0.8396 3.366 -1.0209 66.5652
SU-DHL-4 GDSC2 -0.5319 1.328 -0.5496 38.7565
MOLM-13 GDSC1 -0.5103 2.9187 -0.6044 64.9006
WSU-NHL GDSC2 -0.4845 5.6757 -1.6483 41.673
Loucy GDSC2 -0.3808 5.8294 -1.6005 40.996
SIG-M5 GDSC2 -0.2648 2.0093 -0.3276 36.291
Farage GDSC1 -0.1963 5.2724 -0.7664 59.1015
A4/Fukuda GDSC1 -0.1123 4.3606 -0.4318 59.5214
RCH-ACV GDSC1 -0.0379 4.3032 -0.3374 58.9835
Farage GDSC2 -0.0374 3.4485 -0.3795 35.2743
NU-DUL-1 GDSC2 -0.0168 5.5354 -1.0974 37.7237
EoL-1 GDSC1 -0.008 2.3829 -0.0315 60.8083
SU-DHL-10 GDSC2 0.0123 1.1717 0.0103 33.2228
PL-21 GDSC1 0.1137 7.0003 -1.0148 55.5682
MOLM-13 GDSC2 0.1464 2.7266 -0.0011 32.5941
MOLM-16 GDSC1 0.1551 3.5901 0.0122 58.0053
HT GDSC1 0.1936 3.088 0.122 58.0643
Kasumi-1 GDSC2 0.3153 2.9318 0.1384 31.0576
GR-ST GDSC1 0.3344 5.032 -0.1179 55.2319
RCH-ACV GDSC2 0.352 3.7543 -0.0469 31.7651
Mono-Mac-6 GDSC1 0.39 4.3479 0.1181 55.1833
MC116 GDSC2 0.3985 2.8475 0.2474 30.1001
BONNA-12 GDSC2 0.5075 4.9678 -0.3155 32.1951
CRO-AP2 GDSC1 0.5526 6.187 -0.2474 52.8881
OCI-Ly7 GDSC2 0.5614 3.5012 0.2585 29.2466
ALL-PO GDSC1 0.5823 4.0181 0.3969 53.4703
SKM-1 GDSC1 0.5858 3.6869 0.4595 53.5648
Ramos.2G6.4C10 GDSC1 0.5892 4.6396 0.2651 53.1542
Karpas-231 GDSC1 0.6613 4.6957 0.3295 52.4441
RPMI-8402 GDSC2 0.7221 5.7064 -0.3942 31.5039
NALM-6 GDSC2 0.7401 8.3093 -1.5521 35.4552
EoL-1 GDSC2 0.7574 4.813 0.0109 29.5242
CESS GDSC2 0.7888 5.8817 -0.4006 31.2215
MOLT-16 GDSC2 0.7942 5.0805 -0.0575 29.6743
JVM-2 GDSC2 0.8189 6.1535 -0.4884 31.4486
CRO-AP2 GDSC2 0.9024 6.5467 -0.5786 31.4361
MV4-11 GDSC1 0.9052 4.2646 0.6969 50.0182
EHEB GDSC1 0.9112 9.8635 -1.3691 49.9752
Mono-Mac-6 GDSC2 0.9191 5.1134 0.0605 28.5399
NALM-6 GDSC1 0.9351 4.7676 0.6096 49.7119
EM-2 GDSC1 1.0131 8.4235 -0.6355 49.2938
Reh GDSC1 1.03 5.9108 0.3647 48.8976
SR GDSC1 1.0951 5.0213 0.7151 48.1018
OPM-2 GDSC2 1.1335 4.2086 0.644 24.5768
Karpas-45 GDSC1 1.1762 5.6766 0.602 47.4715
BV-173 GDSC1 1.2919 5.8818 0.6583 46.4278
Karpas-422 GDSC1 1.3101 12.1668 -2.0296 48.0655
P12-Ichikawa GDSC2 1.3114 4.852 0.5801 24.1418
RS4;11 GDSC1 1.3298 7.1128 0.2386 46.6156
A4/Fukuda GDSC2 1.3449 5.829 0.1923 26.0244
Hs 445 GDSC2 1.3507 7.3741 -0.5141 29.2492
Jiyoye GDSC2 1.4135 6.074 0.1511 25.943
Karpas-422 GDSC2 1.4376 14.6919 -4.0008 38.0654
JeKo-1 GDSC1 1.4441 6.7411 0.5062 45.4423
MOLP-8 GDSC1 1.4526 5.8059 0.8583 44.7914
OPM-2 GDSC1 1.4592 2.9322 1.4514 43.1353
CTV-1 GDSC1 1.4815 5.654 0.9409 44.3924
GA-10 GDSC2 1.5116 4.4203 0.9666 21.1529
P31/FUJ GDSC1 1.5156 7.1711 0.4116 45.0601
BL-41 GDSC1 1.5166 5.9913 0.863 44.2719
L-1236 GDSC1 1.5206 9.3568 -0.5235 46.1059
RPMI-8866 GDSC1 1.5372 5.8035 0.9507 43.924
ARH-77 GDSC2 1.5811 5.64 0.5166 23.3547
RL GDSC2 1.6354 5.8939 0.4559 23.4598
BC-1 GDSC2 1.6379 7.758 -0.4189 27.6884
Karpas-620 GDSC2 1.6476 10.8333 -1.9065 32.9062
TALL-1 [Human adult T-ALL] GDSC2 1.6675 6.2337 0.3312 23.9881
ATN-1 GDSC1 1.6867 4.5591 1.4811 41.1715
MV4-11 GDSC2 1.701 4.4402 1.1587 19.2652
PF-382 GDSC2 1.7017 6.4429 0.2674 24.1818
GR-ST GDSC2 1.7097 9.074 -0.9878 29.693
THP-1 GDSC2 1.7667 13.0612 -2.8976 34.9678
KMS-12-BM GDSC1 1.7906 6.5105 0.9648 41.9769
WIL2 NS GDSC2 1.793 4.7043 1.1449 18.9656
MOLM-16 GDSC2 1.7997 4.7931 1.1139 19.1174
P32/ISH GDSC2 1.8066 4.9312 1.0612 19.3938
RPMI-8402 GDSC1 1.8195 6.071 1.1607 41.2206
ATN-1 GDSC2 1.8316 6.0166 0.5945 21.9316
MOLP-8 GDSC2 1.8599 5.728 0.7564 20.9215
SUP-B15 GDSC1 1.8654 5.7724 1.3166 40.385
697 GDSC2 1.8721 6.5594 0.3789 22.9345
TUR GDSC2 1.8756 4.9628 1.1182 18.7877
RPMI-6666 GDSC1 1.9045 9.7296 -0.3071 43.6812
L-1236 GDSC2 1.9746 6.8633 0.3329 22.7849
NOMO-1 GDSC1 2.0488 6.2501 1.3401 38.9925
JVM-3 GDSC2 2.055 6.4137 0.6252 20.9067
RPMI-6666 GDSC2 2.0701 8.2265 -0.2384 25.2389
DG-75 GDSC1 2.0807 7.2308 0.9806 39.9452
SR GDSC2 2.1039 5.1474 1.2668 17.0234
JVM-2 GDSC1 2.1103 9.5326 -0.0113 42.0667
KMS-11 GDSC2 2.1961 11.2756 -1.6281 30.159
MY-M12 GDSC1 2.2041 11.2931 -0.7462 42.766
HH [Human lymphoma] GDSC2 2.2046 7.6737 0.1567 22.8402
DB GDSC1 2.2393 7.8562 0.8762 39.246
L-363 GDSC2 2.2541 6.7588 0.6489 20.0414
PF-382 GDSC1 2.2623 8.2635 0.7191 39.5514
Namalwa GDSC2 2.2771 7.2959 0.4088 21.2677
GA-10 GDSC1 2.2822 8.77 0.5104 39.9793
DEL GDSC2 2.287 7.8935 0.1252 22.7026
H9 GDSC2 2.302 5.8916 1.1124 17.1985
P31/FUJ GDSC2 2.3174 8.2662 -0.0303 23.3627
MHH-CALL-4 GDSC2 2.3202 8.012 0.0975 22.7231
697 GDSC1 2.392 7.2326 1.304 36.8733
Karpas-1106P GDSC1 2.4374 6.5204 1.6477 35.1692
HAL-01 GDSC1 2.4615 5.9529 1.894 33.836
MHH-PREB-1 GDSC1 2.4727 7.8692 1.109 37.0894
SUP-T1 GDSC1 2.5279 6.0874 1.9142 33.3137
Reh GDSC2 2.5793 7.3717 0.6491 18.8966
KMOE-2 GDSC1 2.5822 7.0136 1.5949 34.5091
OCI-AML-2 GDSC2 2.5964 5.8896 1.3927 14.4701
SUP-HD1 GDSC1 2.6203 6.3444 1.9118 32.7546
MOLT-4 GDSC2 2.6207 7.9817 0.3846 20.1986
HAL-01 GDSC2 2.648 6.2372 1.2705 15.0348
SUP-T1 GDSC2 2.6502 9.2038 -0.1959 23.0076
HC-1 GDSC2 2.6529 6.8729 0.9622 16.855
JVM-3 GDSC1 2.6796 7.8775 1.3154 35.1093
Ku812 GDSC1 2.7253 7.2208 1.6535 33.3893
PL-21 GDSC2 2.7263 8.5032 0.2196 20.7083
CCRF-CEM GDSC2 2.7288 6.803 1.0654 15.9922
OCI-AML-3 GDSC1 2.7973 7.4649 1.6196 33.1282
JURL-MK1 GDSC1 2.8053 7.5659 1.5827 33.251
VL51 GDSC2 2.8076 5.226 1.9134 10.5336
CTB-1 GDSC2 2.8189 7.8617 0.6203 18.2558
JSC-1 GDSC2 2.8352 6.0425 1.5374 12.7763
U-698-M GDSC2 2.888 6.5331 1.3418 13.8054
YT GDSC2 2.9189 4.6338 2.3059 7.7091
HL-60 GDSC1 2.9236 7.7377 1.6249 32.3901
P32/ISH GDSC1 2.9257 5.9551 2.3896 28.222
Jurkat GDSC1 2.9735 6.0446 2.4054 27.8504
P30/OHK GDSC1 3.0168 8.8339 1.209 33.6788
JeKo-1 GDSC2 3.0307 16.273 -3.3978 32.3299
MLMA GDSC2 3.0356 9.4782 0.002 20.8027
HH [Human lymphoma] GDSC1 3.0673 18.7578 -3.6056 42.68
SU-DHL-1 GDSC2 3.095 9.7158 -0.066 20.9485
MHH-PREB-1 GDSC2 3.0973 7.2671 1.1592 14.2486
GDM-1 GDSC2 3.1041 6.3247 1.6354 11.3096
NB4 GDSC2 3.1442 6.3861 1.6393 11.1619
SUP-HD1 GDSC2 3.1914 7.3528 1.1967 13.7347
IM-9 GDSC2 3.2054 8.1056 0.8323 15.8359
EB2 GDSC2 3.2316 12.7478 -1.4664 26.3483
BALL-1 GDSC2 3.2562 7.3547 1.2505 13.2153
HL-60 GDSC2 3.2578 6.076 1.8911 9.2417
OCI-M1 GDSC2 3.2673 5.3865 2.2438 6.986
Karpas-45 GDSC2 3.2862 10.6081 -0.3509 21.7014
ALL-PO GDSC2 3.2894 6.2669 1.8222 9.5814
AMO1 GDSC1 3.3031 6.2357 2.6746 24.2957
AMO1 GDSC2 3.3132 6.1166 1.9174 8.913
NK-92MI GDSC2 3.3215 10.5529 -0.2939 21.3328
ML-2 GDSC2 3.4078 7.7077 1.2002 13.0707
KOPN-8 GDSC2 3.4159 7.4563 1.3326 12.2474
SUP-M2 GDSC2 3.4368 6.5628 1.7962 9.3196
NKM-1 GDSC1 3.4544 9.0794 1.5138 30.1418
Karpas-1106P GDSC2 3.4629 6.4585 1.8695 8.7862
CTB-1 GDSC1 3.4732 9.0991 1.5222 30.011
A3/Kawakami GDSC2 3.4762 5.9135 2.1523 6.9677
BE-13 GDSC1 3.4795 8.0486 2.0311 27.3606
CA46 GDSC2 3.4801 6.6511 1.7872 9.2538
KY821 GDSC2 3.5069 6.7439 1.7625 9.3337
ALL-SIL GDSC2 3.513 6.9693 1.6549 9.9874
KMS-12-BM GDSC2 3.5451 10.707 -0.1863 20.1663
OCI-AML-2 GDSC1 3.557 4.7353 3.4768 17.3936
ML-2 GDSC1 3.6072 6.6107 2.8245 21.702
BE-13 GDSC2 3.6174 7.7978 1.3252 11.7224
KMOE-2 GDSC2 3.6407 6.0219 2.2275 6.055
SUP-B8 GDSC1 3.6437 10.3416 1.0764 31.1522
SCC-3 GDSC2 3.6618 5.3321 2.5841 3.7714
KY821 GDSC1 3.6898 6.925 2.7642 21.7106
RL GDSC1 3.6913 7.7141 2.3953 24.1433
DB GDSC2 3.6925 8.0759 1.2462 11.9914
LP-1 GDSC1 3.71 7.1684 2.671 22.2481
SK-MM-2 GDSC2 3.7491 6.8006 1.9245 7.6732
MHH-CALL-2 GDSC2 3.7512 6.0511 2.2965 5.3454
QIMR-WIL GDSC2 3.7801 15.2411 -2.2603 27.379
JSC-1 GDSC1 3.805 8.279 2.233 24.6041
RPMI-8226 GDSC2 3.8158 6.1523 2.2943 5.203
OCI-AML-3 GDSC2 3.8176 9.5009 0.6352 15.1728
JJN-3 GDSC1 3.853 7.5763 2.617 21.9289
RS4;11 GDSC2 3.8711 6.8141 2.0097 6.8362
OCI-Ly19 GDSC1 3.882 8.6648 2.1178 24.93
SKM-1 GDSC2 3.8952 9.1162 0.8876 13.5436
SUP-B15 GDSC2 3.9063 6.9311 1.9782 6.9459
EM-2 GDSC2 3.9268 8.6456 1.1459 11.9599
EJM GDSC2 3.9683 7.4893 1.7493 8.2066
CTV-1 GDSC2 3.9695 7.6985 1.6471 8.831
DG-75 GDSC2 3.9817 8.8053 1.1088 12.0338
KG-1 GDSC2 3.993 6.0263 2.4798 3.6674
Daudi GDSC2 3.9984 6.215 2.3929 4.1815
Ku812 GDSC2 4.0308 6.1545 2.444 3.804
BC-3 GDSC2 4.0582 8.7056 1.2164 11.2035
P30/OHK GDSC2 4.0617 7.4844 1.8204 7.5435
P12-Ichikawa GDSC1 4.0795 9.2487 2.013 24.6454
NB4 GDSC1 4.1157 7.333 2.9846 18.1588
L-428 GDSC2 4.131 7.527 1.8496 7.2022
SK-MM-2 GDSC1 4.1438 9.1137 2.138 23.6371
K-562 GDSC2 4.1549 6.5226 2.3513 4.1036
ME1 GDSC2 4.1894 7.4567 1.9253 6.6064
BV-173 GDSC2 4.191 8.8905 1.2246 10.8213
MY-M12 GDSC2 4.2045 9.0812 1.1406 11.2799
H9 GDSC1 4.2179 5.3542 3.9988 10.1261
Raji GDSC2 4.2472 8.828 1.2968 10.2573
LAMA-84 GDSC2 4.2579 7.2875 2.0545 5.6717
MOLT-13 GDSC2 4.2768 6.0566 2.6446 2.1802
MN-60 GDSC2 4.2882 10.6278 0.4397 14.9771
THP-1 GDSC1 4.2923 11.3732 1.1483 28.0664
LC4-1 GDSC2 4.2929 7.5461 1.954 6.2025
RPMI-8226 GDSC1 4.3081 8.1282 2.7735 18.8217
VAL GDSC2 4.3745 9.6805 0.9715 11.8351
SUP-M2 GDSC1 4.3854 5.5969 4.0685 8.7799
OCI-Ly19 GDSC2 4.481 10.7863 0.5062 14.1375
ST486 GDSC2 4.4975 7.8123 1.9647 5.7068
KCL-22 GDSC2 4.5131 7.4879 2.1283 4.7114
LP-1 GDSC2 4.5195 10.4947 0.6781 13.1164
Granta-519 GDSC1 4.5256 10.0858 1.9932 22.8776
ROS-50 GDSC2 4.5287 7.971 1.9098 5.9681
CML-T1 GDSC2 4.532 8.4587 1.6786 7.3338
TK [Human B-cell lymphoma] GDSC2 4.5616 6.9587 2.4033 3.0477
Karpas-299 GDSC2 4.577 18.739 -3.3673 28.39
HDLM-2 GDSC2 4.6073 8.7634 1.5835 7.7336
RC-K8 GDSC2 4.6148 10.6529 0.6701 12.929
TK [Human B-cell lymphoma] GDSC1 4.6536 8.1393 3.075 15.2419
Granta-519 GDSC2 4.6613 7.2453 2.3322 3.277
U-698-M GDSC1 4.6626 9.2947 2.5062 19.1798
ALL-SIL GDSC1 4.6668 8.1611 3.0756 15.1855
JJN-3 GDSC2 4.6831 7.9992 1.997 5.1504
EJM GDSC1 4.6838 11.0145 1.6652 24.0408
OCI-M1 GDSC1 4.6924 5.6792 4.3301 5.3907
DND-41 GDSC2 4.7057 6.8163 2.5486 2.0486
NOMO-1 GDSC2 4.7091 7.525 2.2331 3.7505
KM-H2 GDSC2 4.7094 13.2053 -0.5164 18.5482
BL-41 GDSC2 4.7253 6.3764 2.7451 1.0835
QIMR-WIL GDSC1 4.7796 7.6488 3.4284 12.0902
WIL2 NS GDSC1 4.828 9.6453 2.4717 18.7639
U266B1 GDSC2 4.8333 6.4298 2.7743 0.8582
DEL GDSC1 4.8389 5.3972 4.603 2.6543
MOLT-13 GDSC1 4.8552 9.0096 2.8123 16.3565
HDLM-2 GDSC1 4.8687 8.0957 3.2806 12.8838
Daudi GDSC1 4.9112 7.803 3.4625 11.3384
YT GDSC1 4.9415 6.4719 4.153 5.8213
Karpas-231 GDSC2 4.9779 6.266 2.8985 0.339
DND-41 GDSC1 5.0633 8.9314 3.0234 14.0843
MC116 GDSC1 5.0843 6.137 4.4327 3.1442
K-562 GDSC1 5.1338 7.8266 3.6316 9.247
L-540 GDSC1 5.1418 7.5147 3.7932 7.9625
HEL GDSC2 5.1931 6.8381 2.7729 0.5931
L-540 GDSC2 5.1961 7.3887 2.5567 1.4247
A3/Kawakami GDSC1 5.2093 6.5912 4.3015 3.7845
Ramos.2G6.4C10 GDSC2 5.2293 6.8012 2.8016 0.4825
EB2 GDSC1 5.2413 7.4143 3.9198 6.6517
SU-DHL-8 GDSC1 5.2883 8.884 3.2265 11.8125
SU-DHL-8 GDSC2 5.3606 6.9072 2.8149 0.3797
MLMA GDSC1 5.3765 10.7531 2.3653 17.4616
CESS GDSC1 5.3878 14.582 0.4641 26.8618
KMS-11 GDSC1 5.4035 7.1661 4.1596 4.3195
Karpas-299 GDSC1 5.4114 10.7886 2.3752 17.2799
Namalwa GDSC1 5.4182 11.4444 2.0539 19.2105
BC-1 GDSC1 5.462 9.9482 2.8326 14.0726
BALL-1 GDSC1 5.4677 9.2819 3.1674 11.6612
VL51 GDSC1 5.4767 10.7567 2.4422 16.633
KCL-22 GDSC1 5.5308 13.9539 0.8922 24.6708
MHH-CALL-2 GDSC1 5.5814 9.5021 3.1443 11.469
MEG-01 GDSC1 5.6198 8.1382 3.8398 6.1505
IM-9 GDSC1 5.655 7.1521 4.3295 2.4517
LC4-1 GDSC1 5.6704 7.4396 4.2062 3.2955
ST486 GDSC1 5.7007 9.3285 3.3177 9.835
CA46 GDSC1 5.798 9.7085 3.2021 10.391
KG-1 GDSC1 6.0051 10.6869 2.8731 12.103
HC-1 GDSC1 6.0073 13.5476 1.4658 20.4821
GDM-1 GDSC1 6.0528 8.1332 4.119 3.0875
CMK GDSC1 6.0777 10.4286 3.0505 10.6653
CML-T1 GDSC1 6.1735 10.5113 3.0772 10.2126
MN-60 GDSC1 6.1967 9.7184 3.4725 7.3447
NKM-1 GDSC2 6.2335 8.561 2.5543 0.6596
OCI-AML-5 GDSC1 6.2582 9.4052 3.6594 5.8603
HEL GDSC1 6.2597 7.6719 4.4234 0.9238
MEG-01 GDSC2 6.2879 8.2173 2.6984 0.2957
VAL GDSC1 6.29 13.5076 1.6977 18.4256
Raji GDSC1 6.3288 9.6633 3.5835 6.2334
Jiyoye GDSC1 6.3622 12.0499 2.4636 13.7665
RC-K8 GDSC1 6.4154 7.9062 4.4008 0.8716
ME1 GDSC1 6.4297 7.6481 4.505 0.431
Sc-1 GDSC1 6.8008 8.2308 4.4383 0.4315
L-428 GDSC1 6.8541 9.7625 3.8455 3.412
ARH-77 GDSC1 6.8976 8.5305 4.3667 0.6167
LAMA-84 GDSC1 7.0827 15.3903 1.3492 17.9905
ROS-50 GDSC1 7.247 12.5034 2.8366 9.1501
KM-H2 GDSC1 8.0314 14.8024 2.2572 10.8949
⏷ Show the Full List of 318 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYAE-1 GDSC1 -2.3047 4.1231 -2.764 72.3777
OACM5.1 C GDSC2 1.7413 8.7522 -0.8015 28.8644
KYAE-1 GDSC2 1.8281 11.2844 -1.9637 32.4311
SK-GT-4 GDSC1 1.8857 8.958 0.0255 43.2815
KYSE-220 GDSC1 1.9617 7.0818 0.9179 40.9118
OACP4 C GDSC1 1.9988 6.8163 1.0651 40.2399
ESO-26 GDSC1 2.2107 10.2184 -0.2314 41.9222
OACP4 C GDSC2 2.5552 7.2258 0.6992 18.6985
SK-GT-4 GDSC2 3.0621 11.7739 -1.1225 25.604
ESO-51 GDSC1 3.6066 6.2401 2.9877 20.5601
KYSE-220 GDSC2 3.9418 7.2962 1.8248 7.8073
FLO-1 GDSC1 4.1021 9.9794 1.6722 26.3867
KYSE-50 GDSC2 4.1385 6.5351 2.3343 4.2389
FLO-1 GDSC2 4.1483 9.8718 0.7076 13.8883
ESO-26 GDSC2 4.3079 8.8521 1.3293 9.9189
HCE-4 GDSC2 4.3184 9.6573 0.9415 12.1438
ESO-51 GDSC2 4.4552 6.8962 2.3677 3.432
OACM5.1 C GDSC1 4.4795 7.8283 3.0763 15.9313
TE-12 GDSC1 5.2767 9.2229 3.0488 13.1569
TE-12 GDSC2 5.3079 8.6388 2.0793 3.6281
KYSE-50 GDSC1 5.3918 8.0999 3.6943 7.929
HCE-4 GDSC1 6.1056 12.5071 2.0536 16.9995
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 -1.3582 4.1221 -1.7332 68.1291
COLO 684 GDSC2 1.4375 7.128 -0.3134 28.0305
Cancer Drug Sensitivity Data Curated from 60 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-12 GDSC2 0.0285 5.2167 -0.9222 36.9324
NB1 GDSC1 1.513 6.2931 0.7498 44.5196
NB1 GDSC2 2.2875 6.0769 1.0097 17.8563
GI-ME-N GDSC1 2.7585 8.4302 1.1426 35.3278
TGW GDSC1 2.812 6.7433 1.9486 31.417
SJNB-6 GDSC2 2.9171 5.5367 1.8614 10.4922
TGW GDSC2 3.0144 4.9019 2.263 7.6557
SK-N-MC-IXC GDSC2 3.3388 11.4122 -0.7091 23.1135
SJNB-13 GDSC2 3.3755 6.0595 1.9975 8.2275
SJNB-12 GDSC1 3.55 7.737 2.2471 25.7515
SJNB-14 GDSC2 3.5733 7.6311 1.3731 11.5544
LA-N-6 GDSC2 3.7417 9.6874 0.4819 16.2189
MHH-NB-11 GDSC2 3.7418 6.9559 1.8419 8.2064
SiMa GDSC2 3.7606 5.7765 2.4382 4.4415
KP-N-YS GDSC2 3.7705 7.0804 1.8022 8.3796
NB(TU)1 GDSC2 3.7976 7.487 1.6214 9.4274
SK-N-SH GDSC1 3.8612 7.3835 2.717 21.2123
SJNB-7 GDSC1 3.8708 6.9238 2.9437 19.5795
NB69 GDSC2 3.8786 10.92 -0.0238 18.4352
CHP-212 GDSC1 3.9143 6.8989 2.998 18.9849
SJNB-17 GDSC2 3.9275 10.8706 0.0396 17.9882
SK-N-FI GDSC2 3.9595 9.5524 0.7208 14.3129
KP-N-RT-BM-1 GDSC2 4.0659 7.5269 1.8026 7.6427
SJNB-14 GDSC1 4.0858 7.4114 2.9183 18.7699
KP-N-YN GDSC2 4.2163 7.905 1.7262 7.7544
SJNB-10 GDSC2 4.2519 7.1285 2.1268 5.2489
NH-12 GDSC2 4.2966 7.29 2.0797 5.4376
SK-N-AS GDSC2 4.3395 8.408 1.5689 8.4178
GOTO GDSC2 4.3542 8.1662 1.6968 7.6171
CHP-134 GDSC2 4.4 6.2055 2.6486 1.9663
SK-N-SH GDSC2 4.4039 10.8166 0.4336 14.7148
Kelly GDSC2 4.4349 8.4546 1.6135 7.9345
SJNB-17 GDSC1 4.4774 9.5807 2.2031 21.8381
CHP-212 GDSC2 4.5468 6.9892 2.3806 3.1992
SK-N-MC-IXC GDSC1 4.5797 6.864 3.6439 11.2044
SK-N-BE(2)-M17 GDSC1 4.6828 8.8035 2.7688 17.324
SJNB-7 GDSC2 4.7711 10.0218 1.0893 10.2358
SJNB-10 GDSC1 4.7909 6.117 4.2026 5.9893
SK-N-DZ GDSC2 4.8564 13.7683 -0.6841 18.9154
GI-ME-N GDSC2 4.9016 14.659 -1.09 20.4708
LA-N-6 GDSC1 4.9217 9.6918 2.5268 18.0495
SK-N-FI GDSC1 4.9885 7.388 3.7337 8.9527
IMR-5 GDSC2 5.0063 6.7603 2.7217 0.9165
SK-N-DZ GDSC1 5.0635 10.7556 2.1121 20.1206
SJNB-13 GDSC1 5.0737 6.9913 4.0002 6.5681
NH-12 GDSC1 5.1937 7.0982 4.0401 5.8642
GOTO GDSC1 5.2076 7.7172 3.7438 8.1302
NB69 GDSC1 5.2457 7.4334 3.9137 6.6857
SK-N-BE(2)-M17 GDSC2 5.286 7.2417 2.6573 0.9326
KP-N-YN GDSC1 5.3775 13.4679 1.012 24.6598
SJNB-5 GDSC1 5.3921 18.8313 -1.6552 32.9771
CHP-126 GDSC2 5.4378 7.3292 2.6892 0.7096
CHP-126 GDSC1 5.6016 8.6846 3.5611 8.3113
SiMa GDSC1 5.8877 8.5364 3.83 5.5198
SJNB-6 GDSC1 5.9998 10.3262 3.0453 10.9233
IMR-5 GDSC1 6.0292 11.4501 2.5169 14.3981
Kelly GDSC1 6.0586 12.5366 2.0042 17.4273
SJNB-5 GDSC2 6.2425 14.7031 -0.1573 13.5072
SK-N-AS GDSC1 6.5532 13.0042 2.1347 15.2245
NB(TU)1 GDSC1 6.9965 8.6086 4.3774 0.5168
⏷ Show the Full List of 60 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 3.7776 8.703 1.001 13.2078
HuCC-T1 GDSC1 5.1125 7.6045 3.7254 8.5898
Cancer Drug Sensitivity Data Curated from 97 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC1 -2.7966 4.9416 -3.5097 72.2755
OCUB-M GDSC1 -2.6797 -0.6219 -2.6803 89.0225
CAL-148 GDSC2 -2.3263 1.1039 -2.408 56.1392
UACC-893 GDSC1 -2.1675 1.787 -2.2368 78.3228
Evsa-T GDSC2 -1.4884 2.1252 -1.6561 48.4315
OCUB-M GDSC2 -1.4332 0.9673 -1.461 47.7657
HCC2157 GDSC2 -1.0657 3.1832 -1.4293 44.8846
UACC-893 GDSC2 -0.6704 4.3882 -1.3667 42.1559
MDA-MB-415 GDSC2 -0.3908 4.0254 -0.9417 39.3311
MDA-MB-175-VII GDSC1 -0.3229 4.5242 -0.7007 60.9231
YMB-1-E GDSC2 -0.3174 4.3488 -0.971 38.9946
CAL-51 GDSC1 -0.2424 9.2343 -2.2859 56.1925
CAMA-1 GDSC2 -0.1581 4.9816 -1.0301 38.2798
MFM-223 GDSC1 0.082 4.7267 -0.3105 57.5658
CAMA-1 GDSC1 0.1255 6.3327 -0.76 55.9284
HCC1569 GDSC2 0.1776 7.9796 -1.9585 38.989
EFM-192A GDSC1 0.2269 5.5031 -0.3749 55.7761
MDA-MB-361 GDSC1 0.3137 5.4001 -0.2487 55.1633
HCC70 GDSC2 0.7551 6.6616 -0.7794 32.8736
MFM-223 GDSC2 0.9854 6.4 -0.4285 30.4512
MDA-MB-175-VII GDSC2 1.1093 7.5027 -0.8113 31.437
HCC1954 GDSC1 1.2041 5.9146 0.5519 47.2827
HCC1569 GDSC1 1.2588 7.7746 -0.1061 47.416
AU565 GDSC1 1.4479 6.6968 0.5274 45.3823
HCC70 GDSC1 1.526 9.1376 -0.4198 45.9777
MCF-7 GDSC1 1.5321 7.0429 0.4806 44.8371
Hs 578T GDSC2 1.6342 10.3369 -1.6752 32.2778
MDA-MB-330 GDSC2 1.7324 8.9688 -0.9153 29.3355
EFM-19 GDSC1 1.7606 19.2193 -5.015 47.3715
Hs 578T GDSC1 1.9229 8.2089 0.3968 42.3832
MDA-MB-453 GDSC1 2.0941 8.4555 0.4624 41.1974
T-47D GDSC1 2.1505 59.586 -24.7623 48.8131
Evsa-T GDSC1 2.152 9.0411 0.256 41.3086
CAL-51 GDSC2 2.2789 11.0185 -1.4267 29.2164
MDA-MB-453 GDSC2 2.3135 7.2959 0.4426 20.9568
AU565 GDSC2 2.3268 10.2493 -1.0024 27.5284
COLO 824 GDSC2 2.3521 7.6395 0.3097 21.524
BT-20 GDSC2 2.4141 9.7734 -0.6884 25.9827
BT-20 GDSC1 2.4338 10.1652 0.0118 40.2983
HCC1954 GDSC2 2.4471 6.6833 0.8661 18.1218
HDQ-P1 GDSC2 2.4785 7.912 0.291 21.1787
T-47D GDSC2 2.7921 12.2811 -1.6064 28.1587
CAL-120 GDSC1 2.8177 7.7007 1.5348 33.396
HCC1419 GDSC1 2.8567 8.1718 1.3595 33.9306
BT-549 GDSC1 2.8643 8.4176 1.2536 34.3186
DU4475 GDSC1 2.9687 5.6367 2.5555 26.926
JIMT-1 GDSC1 3.2787 9.0643 1.3532 31.7348
HCC1187 GDSC1 3.4035 7.8134 2.0677 27.5392
BT-474 GDSC1 3.4138 13.2735 -0.5777 37.1651
MRK-nu-1 GDSC2 3.4672 6.8414 1.6817 9.9493
MDA-MB-361 GDSC2 3.4759 8.4536 0.8832 14.7391
HCC1419 GDSC2 3.7058 9.0078 0.7922 14.605
HCC1395 GDSC2 3.7092 13.9102 -1.653 25.6317
ZR-75-30 GDSC2 3.8151 9.2818 0.7424 14.5836
EFM-19 GDSC2 3.8248 13.7074 -1.4579 24.6312
CAL-120 GDSC2 3.8656 10.4899 0.1804 17.4525
HCC2218 GDSC2 3.9962 9.3704 0.8396 13.5475
UACC-812 GDSC2 4.0468 10.2513 0.4413 15.6014
HCC1500 GDSC2 4.1147 6.4393 2.3642 4.1092
MDA-MB-157 GDSC2 4.1542 8.0417 1.6146 8.5779
BT-549 GDSC2 4.177 11.165 0.0882 17.0738
DU4475 GDSC2 4.2483 7.7214 1.8382 7.0023
COLO 824 GDSC1 4.2982 7.7676 2.9422 17.6678
EFM-192A GDSC2 4.4784 12.2038 -0.1959 17.6675
JIMT-1 GDSC2 4.4979 8.7262 1.526 8.314
BT-474 GDSC2 4.5347 12.9105 -0.503 18.9268
MDA-MB-468 GDSC2 4.5631 12.7982 -0.4257 18.5101
HCC1187 GDSC2 4.6469 10.1202 0.9538 11.2848
MCF-7 GDSC2 4.6908 9.371 1.3482 8.9287
MDA-MB-468 GDSC1 4.696 6.8153 3.7717 9.7436
HCC1599 GDSC2 4.7227 16.3525 -2.0659 24.3847
HCC1143 GDSC2 4.9158 10.2279 1.0901 9.9113
BT-483 GDSC2 4.9593 13.8899 -0.6673 18.5944
HCC38 GDSC2 5.0678 16.849 -2.0474 23.5056
HCC2218 GDSC1 5.1015 11.0329 2.0046 20.6111
HCC1806 GDSC2 5.1478 15.4629 -1.3022 20.703
HCC1428 GDSC2 5.1688 6.4874 2.8923 0.2713
HCC202 GDSC1 5.2149 15.2224 0.0035 29.0533
HDQ-P1 GDSC1 5.2705 7.9792 3.6622 8.5583
MDA-MB-231 GDSC1 5.2932 11.1814 2.0854 19.4576
HCC1937 GDSC2 5.2979 12.4871 0.2634 13.4761
CAL-85-1 GDSC2 5.3733 7.4242 2.6245 0.9865
HCC1937 GDSC1 5.5003 16.2509 -0.2785 29.0545
MDA-MB-436 GDSC2 5.5077 11.6618 0.8027 10.2378
MDA-MB-231 GDSC2 5.5531 7.7136 2.5908 0.9709
MDA-MB-436 GDSC1 5.6423 9.362 3.2586 10.4457
HCC1806 GDSC1 5.6827 8.7792 3.573 7.9857
HCC38 GDSC1 5.6852 9.6699 3.1388 11.1881
MRK-nu-1 GDSC1 5.7648 8.7179 3.6603 7.1014
MDA-MB-157 GDSC1 5.8635 8.4752 3.8431 5.484
HCC1395 GDSC1 5.9189 13.3416 1.5004 20.5828
ZR-75-30 GDSC1 6.0968 12.8143 1.8957 17.9251
HCC1500 GDSC1 6.2706 9.8215 3.472 7.1646
HCC1143 GDSC1 6.4598 9.4025 3.7834 4.5539
BT-483 GDSC1 6.8803 9.3292 4.0433 2.1882
HCC1428 GDSC1 6.8895 8.4159 4.4056 0.4864
CAL-85-1 GDSC1 7.0287 9.2456 4.1478 1.4523
⏷ Show the Full List of 97 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 108 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H4 GDSC1 0.2256 6.1603 -0.5919 55.3435
GaMG GDSC1 0.6167 7.1604 -0.538 52.1248
42-MG-BA GDSC1 0.755 5.3623 0.2437 51.4072
D-336MG GDSC2 0.784 8.4248 -1.5632 35.2991
SF539 GDSC2 1.1527 7.057 -0.5609 30.2722
YH-13 GDSC1 1.158 6.02 0.4654 47.7471
GI-1 GDSC1 1.1753 4.5638 0.9227 47.114
SW1088 GDSC1 1.3081 6.0692 0.6103 46.3571
D-336MG GDSC1 1.7591 8.8983 -0.076 44.1852
SF539 GDSC1 1.7913 5.9337 1.1798 41.3722
SW1088 GDSC2 1.8471 6.5823 0.3438 23.2154
SF295 GDSC1 1.8809 7.5811 0.6246 42.1705
KALS-1 GDSC2 2.1945 7.5808 0.1928 22.6933
H4 GDSC2 2.3759 8.2716 0.0204 22.9088
YKG-1 GDSC1 2.4037 5.9646 1.8277 34.5377
SF126 GDSC2 2.4144 6.8791 0.7401 18.9567
MOG-G-UVW GDSC1 2.5114 6.7275 1.6411 34.7352
D-502MG GDSC2 2.617 8.3355 0.2059 21.1452
8-MG-BA GDSC1 2.6285 6.782 1.7409 33.554
U-118MG GDSC2 2.6308 7.6094 0.5781 19.1156
MOG-G-UVW GDSC2 2.649 7.2993 0.748 18.1034
Becker GDSC1 2.6539 5.9683 2.0943 31.5689
SF295 GDSC2 2.6627 9.0693 -0.118 22.5969
SW1783 GDSC2 2.7915 9.8565 -0.3973 23.4653
DK-MG GDSC1 2.8904 7.449 1.7214 32.1173
M059J GDSC1 2.9373 11.175 0.0109 37.8401
PFSK-1 GDSC2 3.0737 10.4334 -0.4427 22.7685
D-566MG GDSC1 3.0914 4.8846 2.9316 23.7357
SF126 GDSC1 3.1754 8.2634 1.6327 30.9926
Becker GDSC2 3.1891 9.8839 -0.0704 20.6781
U-118MG GDSC1 3.1958 7.6633 1.9318 29.3699
SK-MG-1 GDSC2 3.2157 11.2742 -0.7431 23.6264
D283 Med GDSC2 3.2712 5.8976 1.9916 8.5687
SK-MG-1 GDSC1 3.3044 10.4659 0.7004 34.1193
YH-13 GDSC2 3.3311 9.2823 0.3494 18.1186
42-MG-BA GDSC2 3.3705 10.9523 -0.4528 21.9077
GI-1 GDSC2 3.3862 7.0508 1.5108 11.241
M059J GDSC2 3.4213 8.8879 0.6213 16.379
8-MG-BA GDSC2 3.4267 9.3971 0.3713 17.7175
MOG-G-CCM GDSC1 3.4584 7.8683 2.0957 27.1008
MOG-G-CCM GDSC2 3.4742 10.9737 -0.3778 21.2625
LN-18 GDSC2 3.5008 7.2219 1.5189 10.8637
GB-1 GDSC2 3.5386 7.9957 1.1631 12.9174
D-542MG GDSC2 3.6289 10.3874 0.0417 18.818
LN-405 GDSC1 3.6419 6.9931 2.6851 22.4859
CAS-1 GDSC2 3.6511 7.331 1.5847 10.0429
Onda 10 GDSC2 3.6595 11.3345 -0.4066 20.8549
KNS-81-FD GDSC2 3.6758 11.05 -0.2513 20.0948
KINGS-1 GDSC1 3.7052 9.8946 1.3523 29.6933
GB-1 GDSC1 3.7086 7.5802 2.4757 23.5466
NMC-G1 GDSC2 3.7365 11.3801 -0.3671 20.4561
T98G GDSC2 3.7697 8.4404 1.1256 12.499
U-251MG GDSC1 3.7901 10.7087 1.0298 30.6863
KALS-1 GDSC1 3.8185 14.252 -0.7011 35.8887
D-263MG GDSC2 3.8233 7.3714 1.6984 8.8863
GaMG GDSC2 3.8782 13.0131 -1.0682 23.025
KNS-81-FD GDSC1 3.897 9.6934 1.6275 27.5174
D-245MG GDSC2 3.9135 8.2605 1.3267 10.9186
KS-1 [Human Krukenberg tumour] GDSC2 3.9723 6.9623 2.0112 6.5829
LN-405 GDSC2 3.9809 8.4114 1.3033 10.8845
D-423MG GDSC1 4.0619 9.4534 1.896 25.3768
T98G GDSC1 4.0757 8.3038 2.4743 21.851
SNB-75 GDSC2 4.0853 8.8414 1.1697 11.4096
Daoy GDSC2 4.0925 7.4007 1.8836 7.0841
CAS-1 GDSC1 4.0946 11.016 1.1516 28.8679
D-423MG GDSC2 4.222 13.5683 -1.0718 22.1137
KS-1 [Human Krukenberg tumour] GDSC1 4.2335 10.5506 1.5059 26.6588
U-87MG ATCC GDSC1 4.2383 11.6487 0.9638 29.0651
ONS-76 GDSC2 4.3301 9.6978 0.9302 12.1795
D-392MG GDSC1 4.3629 8.4851 2.6464 19.4636
AM-38 GDSC2 4.441 10.9747 0.3834 14.8851
LN-229 GDSC2 4.4557 9.564 1.0879 10.9732
Onda 11 GDSC2 4.4818 11.5606 0.1248 16.1034
SNB-75 GDSC1 4.493 22.6007 -4.2872 39.486
D-566MG GDSC2 4.5413 10.0655 0.9045 11.8111
LN-18 GDSC1 4.5465 7.503 3.2975 14.0033
KINGS-1 GDSC2 4.5738 11.7056 0.1222 15.8857
ONS-76 GDSC1 4.5768 7.3847 3.3832 13.2284
Daoy GDSC1 4.6116 11.8167 1.2029 26.5637
SF268 GDSC2 4.6443 7.6389 2.1407 4.3919
D-392MG GDSC2 4.6528 10.1004 0.9676 11.1937
YKG-1 GDSC2 4.6775 13.8608 -0.8648 20.1139
SW1783 GDSC1 4.6799 8.9451 2.6957 17.8402
Hs 683 GDSC1 4.6943 9.5531 2.4044 19.715
DBTRG-05MG GDSC2 4.9472 11.3384 0.5742 12.6645
D283 Med GDSC1 5.013 11.508 1.6943 22.6478
Onda 10 GDSC1 5.0362 12.728 1.1036 25.4369
DK-MG GDSC2 5.1184 12.1976 0.2775 13.8085
D-542MG GDSC1 5.1214 9.2261 2.9234 14.5979
Hs 683 GDSC2 5.1279 13.0423 -0.1277 15.7662
AM-38 GDSC1 5.2243 8.8802 3.1781 12.3877
A-172 GDSC2 5.2674 15.476 -1.2198 20.1106
D-247MG GDSC2 5.3074 8.1794 2.2801 2.5955
DBTRG-05MG GDSC1 5.391 8.0352 3.7256 7.6907
LN-229 GDSC1 5.4456 9.2478 3.1674 11.732
D-502MG GDSC1 5.4689 9.0466 3.2847 10.7917
SF268 GDSC1 5.4991 9.7892 2.94 13.1979
A-172 GDSC1 5.5218 7.8052 3.9327 5.7181
NMC-G1 GDSC1 5.5548 8.0682 3.8283 6.4199
U-251MG GDSC2 5.5967 14.3604 -0.4356 16.1171
KNS-42 GDSC2 5.5979 7.5158 2.6853 0.623
KNS-42 GDSC1 5.6223 8.0051 3.9058 5.6449
PFSK-1 GDSC1 5.659 9.8778 3.017 12.1422
LNZTA3WT4 GDSC1 5.6596 12.1895 1.8723 19.4379
D-263MG GDSC1 5.6613 15.181 0.3842 26.2866
D-247MG GDSC1 5.827 12.6109 1.7922 19.3381
Onda 11 GDSC1 6.4732 10.9462 3.0717 9.4565
U-87MG ATCC GDSC2 7.931 26.4513 -4.663 24.8093
⏷ Show the Full List of 108 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC2 3.1172 13.5005 -1.9389 28.2489
ETK-1 GDSC2 3.5548 10.3209 0.0146 19.1669
TGBC24TKB GDSC2 3.5574 7.7546 1.2987 12.0501
TGBC1TKB GDSC1 4.4285 13.171 0.3697 30.5593
TGBC24TKB GDSC1 4.5112 8.8638 2.5897 19.233
ETK-1 GDSC1 5.0617 9.4677 2.7542 15.9993
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-296 GDSC1 -6.341 10.0609 -9.0798 72.1095
MFE-319 GDSC1 -1.7372 4.9296 -2.3502 68.322
RL95-2 GDSC2 -0.0825 4.8464 -0.898 37.4483
AN3-CA GDSC1 0.3468 8.4376 -1.3368 53.4629
AN3-CA GDSC2 1.3575 6.898 -0.2843 28.2307
EN GDSC2 1.7605 9.7781 -1.2847 30.5594
MFE-280 GDSC2 3.1698 10.1067 -0.1981 21.3481
EN GDSC1 3.4416 10.611 0.7574 33.2854
ESS-1 GDSC2 3.4892 8.6108 0.8155 15.0886
MFE-296 GDSC2 4.0804 8.7703 1.2011 11.2372
KLE GDSC2 4.5156 13.4086 -0.7644 20.1036
MFE-319 GDSC2 4.791 13.5668 -0.6336 18.8584
KLE GDSC1 5.3491 11.0446 2.1983 18.589
ESS-1 GDSC1 5.9711 14.0722 1.1781 21.988
MFE-280 GDSC1 6.297 9.5331 3.6242 6.0198
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 64 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB996-RCC GDSC1 -0.2405 3.4305 -0.3873 61.7994
KTCTL-26A GDSC1 0.7607 11.3295 -2.1845 50.719
KTCTL-140 GDSC2 1.0795 5.329 0.1377 27.4433
A-498 GDSC2 1.1742 7.4852 -0.7394 30.8889
BFTC-909 GDSC2 1.1747 8.5185 -1.2278 32.6362
CAL-54 GDSC2 1.4524 11.9714 -2.645 35.4628
KTCTL-140 GDSC1 1.4663 4.6027 1.2306 43.8245
KMRC-1 GDSC1 1.4956 6.5094 0.6501 44.8291
KTCTL-26A GDSC2 1.5823 10.3461 -1.7277 32.6251
LB996-RCC GDSC2 1.8646 8.2202 -0.4272 26.8505
SW156 GDSC1 1.9016 7.9669 0.4805 42.3461
BFTC-909 GDSC1 1.9453 7.281 0.8181 41.2846
RXF 393L GDSC2 2.3076 10.3531 -1.0711 27.8529
RXF 393L GDSC1 2.419 7.4601 1.2339 36.9676
A-498 GDSC1 2.4204 9.4685 0.3258 39.6606
UO-31 GDSC1 2.9065 5.8252 2.4187 28.1513
KMRC-1 GDSC2 3.0734 10.8727 -0.6625 23.7246
786-O GDSC2 3.178 11.1695 -0.7224 23.6547
LB1047-RCC GDSC1 3.2338 6.9743 2.2826 27.1672
Caki-1 GDSC1 3.2476 8.1586 1.7527 30.0268
UO-31 GDSC2 3.4184 8.8332 0.6463 16.2489
NCC021 GDSC2 3.4184 11.3231 -0.5985 22.4051
RCC10RGB GDSC2 3.678 10.592 -0.0208 18.9854
NCC021 GDSC1 3.7542 9.8474 1.4207 29.1578
KTCTL-1M GDSC2 3.784 7.9416 1.385 10.908
KTCTL-195 GDSC1 3.7851 7.0499 2.8003 20.9985
LB2241-RCC GDSC1 3.8379 10.3806 1.235 29.6139
SW156 GDSC2 3.8782 8.9321 0.9659 13.1397
KTCTL-21 GDSC2 3.9181 15.4927 -2.2741 27.0561
OS-RC-2 GDSC2 3.9301 10.0862 0.4323 15.9641
LB1047-RCC GDSC2 3.9373 12.6342 -0.8319 21.9127
VMRC-RCZ GDSC1 4.08 10.2172 1.5346 27.1704
TK-10 GDSC2 4.1633 9.1128 1.0942 11.6536
SW13 GDSC1 4.2869 8.6814 2.481 20.8858
KTCTL-195 GDSC2 4.3761 9.9332 0.8484 12.5265
769-P GDSC2 4.3773 8.2304 1.6819 7.6547
SW13 GDSC2 4.398 10.7988 0.438 14.7067
TK-10 GDSC1 4.4066 7.8235 3.0132 16.695
Caki-1 GDSC2 4.4115 10.6012 0.5457 14.1
KTCTL-1M GDSC1 4.445 6.9977 3.4554 13.2154
BB65-RCC GDSC2 4.5136 8.8848 1.4602 8.6677
LB2241-RCC GDSC2 4.5853 10.8124 0.5703 13.5386
KTCTL-13 GDSC2 4.6001 9.7053 1.1225 10.4359
A-704 GDSC2 4.6346 21.0651 -4.4808 30.7135
ACHN GDSC1 4.6356 8.4267 2.9161 16.4684
KMRC-20 GDSC2 4.6841 9.1174 1.4658 8.2587
SN12C GDSC1 4.7134 7.0548 3.6677 10.4879
SN12C GDSC2 4.8255 11.2713 0.52 13.2331
ACHN GDSC2 4.8431 12.3376 0.0104 15.7768
769-P GDSC1 5.0032 8.3448 3.2675 12.492
KMRC-20 GDSC1 5.0246 9.8693 2.5231 17.6926
VMRC-RCW GDSC2 5.0298 10.8316 0.8775 10.843
OS-RC-2 GDSC1 5.1023 12.1022 1.4708 23.47
CAL-54 GDSC1 5.1762 10.8054 2.1789 19.3138
KTCTL-13 GDSC1 5.1965 6.727 4.2254 4.4124
HA7-RCC GDSC1 5.2172 6.852 4.1793 4.7075
NCC010 GDSC2 5.247 10.8203 1.0303 9.5413
HA7-RCC GDSC2 5.3501 12.2771 0.4012 12.6646
BB65-RCC GDSC1 5.4221 8.697 3.4222 9.9098
RCC10RGB GDSC1 5.7045 10.3131 2.8363 13.2669
KTCTL-21 GDSC1 6.1939 11.3285 2.6952 12.7535
NCC010 GDSC1 6.2796 8.7794 3.9597 3.7189
VMRC-RCZ GDSC2 6.7475 17.1194 -0.973 16.0002
786-O GDSC1 7.5197 8.9591 4.4467 0.1504
⏷ Show the Full List of 64 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H508 GDSC1 -1.0555 8.4671 -2.8281 60.4346
NCI-H508 GDSC2 0.5425 6.8554 -1.082 34.9077
KM12 GDSC2 0.9805 6.096 -0.2977 29.9118
SNU-C1 GDSC1 1.2263 5.3758 0.753 46.8674
LS411N GDSC2 1.4256 6.5564 -0.0582 26.9097
LoVo GDSC1 1.5425 10.2738 -0.9186 46.3139
NCI-H716 GDSC1 1.6044 5.3473 1.1736 42.834
SW48 GDSC2 1.7632 10.7694 -1.7691 32.0943
HCC2998 GDSC1 2.0569 8.7254 0.3035 41.7615
SNU-C1 GDSC2 2.0742 6.0294 0.8265 19.7038
NCI-H747 GDSC2 2.4019 9.375 -0.5018 25.2338
LoVo GDSC2 2.5017 7.3056 0.6112 19.3744
DiFi GDSC1 2.5777 7.2333 1.4959 34.9674
SW948 GDSC2 2.6231 7.9151 0.4198 20.0027
SNU-C5 GDSC2 2.743 9.2099 -0.1175 22.3275
NCI-H716 GDSC2 2.7777 6.1233 1.4454 13.5329
DiFi GDSC2 2.8622 5.9096 1.6275 12.1295
HCC2998 GDSC2 2.8632 8.6671 0.2581 20.0596
GP5d GDSC2 2.9718 9.1074 0.1324 20.354
KM12 GDSC1 2.9836 6.2057 2.3515 28.1256
GP5d GDSC1 3.079 10.091 0.6692 35.3022
HCT 116 GDSC2 3.255 8.5426 0.6556 16.6855
HCT 116 GDSC1 3.3563 6.674 2.5407 24.898
SW48 GDSC1 3.3611 7.3719 2.2307 26.8086
COLO 320HSR GDSC2 3.3878 5.7351 2.1698 7.1048
MDST8 GDSC1 3.4609 8.5954 1.7526 28.9446
HT-55 GDSC2 3.4823 8.8401 0.6953 15.7882
HCT 15 GDSC2 3.5022 9.6847 0.2895 17.9249
HT-29 GDSC2 3.5288 8.1073 1.0993 13.3243
COLO205 GDSC1 3.606 8.5684 1.9044 27.436
C2BBe1 GDSC2 3.6257 11.0313 -0.2826 20.3841
SNU-81 GDSC2 3.7611 12.761 -1.0368 23.2264
LS513 GDSC1 3.7927 7.1006 2.7841 21.0748
CCK-81 GDSC2 3.8153 6.7506 1.9993 7.0391
RKO GDSC2 3.8753 8.6852 1.0864 12.4461
CaR-1 GDSC2 3.9077 7.4675 1.7148 8.5704
MDST8 GDSC2 3.976 10.0793 0.4716 15.6296
SK-CO-1 GDSC2 3.9943 9.399 0.8239 13.6413
SNU-407 GDSC2 4.0545 8.2854 1.4211 9.9911
LS411N GDSC1 4.0888 10.7382 1.2842 28.3079
SNU-283 GDSC2 4.1269 7.254 1.9796 6.4171
SNU-81 GDSC1 4.1748 14.3079 -0.4168 33.8783
SW1116 GDSC2 4.2616 10.3998 0.5323 14.5519
NCI-H747 GDSC1 4.2661 10.2029 1.7076 25.5057
RCM-1 [Human ESC] GDSC1 4.2981 8.2161 2.7211 19.2273
COLO205 GDSC2 4.3089 11.5294 0.009 17.1193
SNU-175 GDSC2 4.3677 8.0462 1.7644 7.1808
CaR-1 GDSC1 4.4243 9.7076 2.0934 22.71
LS180 GDSC2 4.5335 12.2002 -0.1524 17.3221
SNU-61 GDSC2 4.5884 9.1403 1.3886 8.9203
SW1417 GDSC2 4.609 11.8236 0.0902 15.9569
T84 GDSC2 4.6493 14.7228 -1.3136 21.9498
CW-2 GDSC2 4.8063 9.0043 1.6022 7.2054
SW1463 GDSC2 4.8742 11.2831 0.5491 12.9654
LS1034 GDSC2 4.8801 6.3489 2.8268 0.6224
HCT 15 GDSC1 4.9994 7.7285 3.5725 10.1709
SNU-407 GDSC1 5.0058 9.9114 2.4866 18.0003
CL-11 GDSC2 5.0532 8.5773 1.9585 4.6972
COLO 678 GDSC2 5.0662 7.3291 2.5175 1.744
SK-CO-1 GDSC1 5.084 6.5739 4.216 4.8398
LS123 GDSC2 5.1824 9.8929 1.4274 7.4557
C2BBe1 GDSC1 5.2432 8.1959 3.5336 9.6384
SW620 GDSC2 5.2448 9.8662 1.4799 7.0401
SW837 GDSC2 5.2771 10.0184 1.4291 7.2633
SNU-C2B GDSC2 5.2777 12.0055 0.4822 12.4065
LS180 GDSC1 5.306 7.3618 3.9941 5.8749
HT115 GDSC2 5.3243 6.548 2.9283 0.1514
COLO 320HSR GDSC1 5.3389 8.4887 3.462 9.8738
SNU-C2B GDSC1 5.4839 9.2878 3.1767 11.5408
RKO GDSC1 5.5019 10.6392 2.5202 16.0445
HT-29 GDSC1 5.5327 7.0307 4.3102 2.8634
HT115 GDSC1 5.583 7.9737 3.8939 5.8427
SW1116 GDSC1 5.5883 8.9432 3.4246 9.3777
LS1034 GDSC1 5.603 9.0421 3.3868 9.6153
CCK-81 GDSC1 5.607 8.8091 3.504 8.7255
SW1417 GDSC1 5.6431 8.6503 3.6076 7.8396
LS123 GDSC1 5.8506 12.4638 1.8832 18.7608
RCM-1 [Human ESC] GDSC2 5.9691 13.0471 0.449 11.1417
SW620 GDSC1 6.0384 9.0486 3.686 6.1971
SW948 GDSC1 6.1166 8.6933 3.9017 4.4636
CL-11 GDSC1 6.1647 10.1351 3.2522 9.0026
SNU-61 GDSC1 6.2566 12.6749 2.0823 16.3817
SW626 GDSC1 6.2585 8.6584 4.0019 3.475
SW626 GDSC2 6.2678 8.6847 2.5223 0.7333
CW-2 GDSC1 6.2768 8.8153 3.9419 3.8457
T84 GDSC1 6.3039 9.2637 3.7534 5.0935
COLO 678 GDSC1 6.3119 10.0964 3.3689 7.7937
SW837 GDSC1 6.7069 8.5416 4.2811 1.1437
HT-55 GDSC1 6.9592 14.8125 1.5427 17.3519
SW1463 GDSC1 7.4757 9.0256 4.4088 0.2281
SNU-C5 GDSC1 7.7112 9.3488 4.3817 0.2139
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 2.8804 8.6526 1.1603 34.5944
MO-T GDSC2 3.828 5.8225 2.4642 4.1237
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC2 1.0276 7.6855 -0.9773 32.391
Hep 3B2.1-7 GDSC1 1.3765 4.7771 1.0887 44.9639
JHH-2 GDSC1 2.5237 14.1357 -1.8181 42.746
JHH-2 GDSC2 3.0701 10.2376 -0.348 22.353
JHH-6 GDSC1 3.1486 8.412 1.5367 31.5833
HuH-1 GDSC2 3.6681 7.9633 1.283 11.8375
Huh-7 GDSC2 3.8592 5.8588 2.4686 4.0263
HuH-1 GDSC1 3.9654 7.6654 2.6815 20.9705
JHH-7 GDSC2 4.0285 6.4664 2.2925 4.7266
JHH-7 GDSC1 4.2386 8.8718 2.3432 21.9743
SNU-449 GDSC2 4.3464 15.2874 -1.83 24.5435
SNU-423 GDSC1 4.3609 9.0662 2.3564 21.3723
SNU-423 GDSC2 4.3844 13.5538 -0.9378 21.1552
HLE GDSC2 4.4448 10.0804 0.8267 12.4793
JHH-4 GDSC2 4.5002 6.6289 2.5165 2.5233
JHH-1 GDSC2 4.513 11.1167 0.3672 14.7896
Hep-G2/C3A GDSC2 4.6704 6.892 2.496 2.3729
Huh-7 GDSC1 4.6923 10.5161 1.9215 22.6224
SNU-398 GDSC2 4.8711 10.2182 1.0639 10.1569
SK-HEP-1 GDSC2 4.9046 9.0518 1.6442 6.7643
JHH-6 GDSC2 4.9731 13.9593 -0.6912 18.6637
SNU-387 GDSC1 5.2916 7.1517 4.0868 5.2005
SNU-387 GDSC2 5.3276 14.5719 -0.7317 18.004
Hep-G2/C3A GDSC1 5.3493 8.1423 3.6415 8.4673
SK-HEP-1 GDSC1 5.368 6.8139 4.3049 3.3147
HLE GDSC1 5.8277 8.8445 3.6426 7.063
JHH-1 GDSC1 6.5097 8.651 4.1416 2.1499
SNU-398 GDSC1 6.6506 8.5435 4.2546 1.3363
SNU-449 GDSC1 7.2819 8.9686 4.3576 0.4254
JHH-4 GDSC1 8.2176 14.3128 2.5926 8.599
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 358 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H720 GDSC1 -1.2858 3.8742 -1.6 68.2645
DMS 273 GDSC1 -0.5243 11.0279 -3.3507 56.4603
IST-SL2 GDSC1 -0.3174 2.6497 -0.3727 63.6191
NCI-H720 GDSC2 -0.1958 4.5857 -0.9236 38.1562
HCC44 GDSC1 -0.1843 4.8188 -0.6254 59.5322
SBC-1 GDSC2 -0.0784 12.3894 -4.2842 43.4802
IST-SL2 GDSC2 0.0852 3.1393 -0.1622 33.6678
DMS 273 GDSC2 0.4697 6.7675 -1.1169 35.3614
NCI-H1155 GDSC1 0.5749 4.5541 0.2707 53.3255
NCI-H446 GDSC1 0.859 5.522 0.3072 50.4411
NCI-H1975 GDSC2 0.8897 8.5539 -1.5209 34.7301
Lu-134-A GDSC2 1.0194 4.2116 0.5203 25.7499
NCI-H2171 GDSC2 1.0216 3.5123 0.7571 24.4752
RERF-LC-Sq1 GDSC2 1.1052 5.2611 0.1933 27.0535
NCI-H2373 GDSC1 1.2633 8.7273 -0.5076 47.6449
NCI-H460 GDSC1 1.2654 5.1467 0.8648 46.3669
NCI-H1770 GDSC1 1.3135 3.8807 1.2104 45.2437
NCI-H1648 GDSC2 1.3217 6.3011 -0.0445 27.2784
Lu-134-A GDSC1 1.4594 4.9794 1.1244 44.1612
NCI-H292 GDSC1 1.4968 6.6995 0.5785 44.9382
RERF-LC-Sq1 GDSC1 1.5051 5.9422 0.8678 44.3532
HARA [Human squamous cell lung carcinoma] GDSC1 1.5363 8.2043 0.0007 45.4655
COR-L32 GDSC2 1.5795 5.0968 0.7552 22.0539
NCI-H1975 GDSC1 1.5857 6.2132 0.8573 43.7489
EBC-1 GDSC1 1.6436 24.544 -7.7482 48.2549
NCI-H460 GDSC2 1.6674 7.1635 -0.1063 26.1594
KNS-62 GDSC2 1.7831 8.3916 -0.587 27.8399
NCI-H2110 GDSC1 1.8058 10.2491 -0.6453 44.6473
LXF 289 GDSC1 1.8453 8.3609 0.2504 43.1416
HCC44 GDSC2 1.8461 7.0773 0.107 24.4291
EPLC-272H GDSC2 1.8986 9.5194 -1.0304 29.1486
NCI-H2122 GDSC2 1.9402 5.7807 0.8117 20.2978
NCI-H526 GDSC1 2.1054 7.3336 0.9631 39.8359
COR-L311 GDSC2 2.1446 7.4868 0.1922 22.8786
NCI-H292 GDSC2 2.2059 8.0278 -0.0155 23.6896
EPLC-272H GDSC1 2.2246 8.7796 0.4481 40.4625
NCI-H1755 GDSC1 2.2281 4.9523 1.9709 34.9647
NCI-H446 GDSC2 2.2772 7.8606 0.1324 22.7013
NCI-H2373 GDSC2 2.2904 9.036 -0.4346 25.329
NCI-H69 GDSC2 2.4304 7.7218 0.3411 21.0837
NCI-H1993 GDSC2 2.5067 7.8833 0.3307 20.8736
Lu-65 GDSC2 2.5369 6.149 1.2107 15.7774
NCI-H1623 GDSC1 2.5384 5.8016 2.0325 32.6218
NCI-H647 GDSC1 2.5446 6.8742 1.6147 34.6495
RERF-LC-MS GDSC1 2.6791 6.5382 1.8953 32.4825
SBC-1 GDSC1 2.6903 4.7389 2.5316 28.718
COR-L23 GDSC2 2.7039 10.056 -0.5731 24.5237
NCI-H647 GDSC2 2.7086 8.3747 0.2678 20.518
NCI-H2196 GDSC2 2.8689 8.4397 0.3764 19.4194
NCI-H1155 GDSC2 2.9271 5.9948 1.6437 11.8175
EMC-BAC-2 GDSC2 2.9522 9.4302 -0.0456 21.3007
NCI-H2110 GDSC2 2.9591 8.2686 0.5401 18.2455
NCI-H1755 GDSC2 3.0428 8.3569 0.5682 17.8256
NCI-H2081 GDSC2 3.0605 9.2059 0.1593 19.9367
NCI-H2066 GDSC2 3.084 6.1703 1.6949 11.001
NCI-H2170 GDSC2 3.1138 11.8084 -1.0959 25.3448
HARA [Human squamous cell lung carcinoma] GDSC2 3.1207 8.3351 0.6457 17.1527
NCI-H209 GDSC2 3.1942 8.2047 0.7732 16.208
NCI-H1770 GDSC2 3.2256 9.2962 0.2541 18.937
NCI-H1944 GDSC2 3.2312 8.2863 0.7637 16.1493
NCI-H520 GDSC2 3.2472 9.1638 0.3385 18.4297
NCI-H847 GDSC2 3.2578 8.1351 0.8617 15.5081
COR-L279 GDSC2 3.2644 9.4418 0.2139 19.0265
HOP-92 GDSC1 3.2762 10.5579 0.6291 34.4898
RERF-LC-MS GDSC2 3.291 8.2687 0.8227 15.632
NCI-H2810 GDSC1 3.3039 8.5354 1.6298 30.3426
NCI-H3122 GDSC2 3.3042 8.5161 0.7101 16.2315
NCI-H1734 GDSC2 3.3283 7.2051 1.3857 12.1785
NCI-H1341 GDSC1 3.345 6.6791 2.5269 25.0469
NCI-H835 GDSC2 3.3471 11.5044 -0.7484 23.2531
Lu-99A GDSC2 3.3477 9.0003 0.5042 17.2399
NCI-H69 GDSC1 3.3902 9.0002 1.4908 30.5642
Lu-99A GDSC1 3.4142 13.3443 -0.6123 37.2401
NCI-H1781 GDSC2 3.4352 10.2756 -0.061 19.8885
HCC33 GDSC2 3.4516 9.2502 0.4651 17.1427
NCI-H1703 GDSC1 3.4539 9.097 1.5048 30.1861
LB647-SCLC GDSC2 3.5177 9.0532 0.6177 16.1168
CPC-N GDSC2 3.5292 8.9873 0.6601 15.8488
SBC-5 GDSC2 3.5358 8.966 0.6761 15.7406
LOU-NH91 GDSC1 3.5914 8.1561 2.0882 26.4825
PaCa-3 GDSC1 3.6501 7.519 2.4477 24.0109
LC-2/ad GDSC2 3.6911 8.057 1.2546 11.9452
NCI-H82 GDSC1 3.7024 7.8337 2.3491 24.38
NCI-H64 GDSC2 3.7097 10.7345 -0.0664 19.117
NCI-H345 GDSC2 3.7121 7.246 1.6748 9.3225
NCI-H596 GDSC2 3.7363 8.6643 0.9877 13.3985
NCI-H1048 GDSC1 3.74 9.703 1.4783 28.9547
SHP-77 GDSC2 3.744 6.1227 2.2559 5.6165
EKVX GDSC2 3.7483 7.4567 1.5983 9.6991
NCI-H64 GDSC1 3.7829 8.6177 2.0479 25.7952
LCLC-103H GDSC1 3.7852 8.5906 2.0632 25.6967
NCI-H322M GDSC2 3.8056 8.7344 1.0074 13.0946
NCI-H835 GDSC1 3.8057 9.5749 1.6018 28.059
NCI-H250 GDSC2 3.8174 9.7939 0.489 15.9696
NCI-H661 GDSC1 3.8275 8.3908 2.2001 24.6963
NCI-H187 GDSC1 3.8283 11.7281 0.5604 32.277
NCI-H2228 GDSC2 3.8357 8.8546 0.9712 13.2234
NCI-H838 GDSC2 3.8375 9.9594 0.4225 16.2701
COR-L105 GDSC2 3.8475 8.2086 1.3016 11.2419
NCI-H524 GDSC2 3.8515 8.395 1.2121 11.7663
NCI-H1703 GDSC2 3.8515 10.3672 0.2303 17.236
NCI-H2023 GDSC2 3.8625 10.0835 0.3804 16.4241
NCI-H1694 GDSC2 3.8958 9.0389 0.9265 13.3194
NCI-H1648 GDSC1 3.9053 10.5605 1.2074 29.4376
PC-14 GDSC2 3.9216 10.1026 0.4174 16.0661
NCI-H1581 GDSC2 3.9277 5.8226 2.5333 3.4822
NCI-H2291 GDSC2 3.9301 6.9209 2.0007 6.7487
NCI-H2461 GDSC2 3.944 10.3237 0.325 16.4916
NCI-H226 GDSC2 3.9448 8.5414 1.2114 11.5251
NCI-H2009 GDSC2 3.9477 8.7481 1.1111 12.1097
NCI-H526 GDSC2 3.9651 6.0532 2.448 3.9187
NCI-H82 GDSC2 3.9697 7.7994 1.5974 9.1343
NCI-H1048 GDSC2 3.976 10.3651 0.3295 16.381
LXF 289 GDSC2 3.99 7.3081 1.8545 7.5067
NCI-H211 GDSC2 3.9959 7.6031 1.7138 8.357
NCI-H2369 GDSC2 4.0001 7.7552 1.6419 8.7868
LCLC-103H GDSC2 4.0036 7.9761 1.5356 9.4257
PC-14 GDSC1 4.0168 7.1884 2.96 18.7833
SBC-5 GDSC1 4.0307 7.6655 2.7433 20.2489
NCI-H2405 GDSC2 4.0598 7.3645 1.8778 7.1966
COR-L23 GDSC1 4.0639 8.6043 2.316 22.9098
A-427 GDSC1 4.0733 6.5862 3.3008 16.0207
DMS 114 GDSC1 4.0801 9.7817 1.7503 26.0781
A-427 GDSC2 4.0879 8.34 1.4192 9.9194
NCI-H2030 GDSC1 4.0972 11.3735 0.9763 29.5916
NCI-H2170 GDSC1 4.1015 10.9575 1.1867 28.6867
NCI-H2030 GDSC2 4.1025 7.1187 2.0282 6.1758
NCI-H520 GDSC1 4.1143 11.9504 0.7046 30.5801
HCC827 GDSC2 4.1233 9.3452 0.9493 12.5917
NCI-H1876 GDSC2 4.1327 7.6709 1.7805 7.6197
LCLC-97TM1 GDSC2 4.1333 8.377 1.4346 9.7146
NCI-H1836 GDSC2 4.1405 6.3552 2.4213 3.7153
Ms-1 GDSC1 4.145 8.425 2.4786 21.5161
HCC366 GDSC2 4.1716 15.5084 -2.0785 25.7974
NCI-H2085 GDSC2 4.1815 9.7165 0.8097 13.2335
NCI-H2444 GDSC2 4.1824 9.4097 0.962 12.3685
NCI-H1688 GDSC1 4.1841 7.4059 3.0136 17.645
NCI-H2795 GDSC2 4.1923 12.3619 -0.4948 19.7796
NCI-H2461 GDSC1 4.2028 11.8636 0.8257 29.7609
NCI-H1436 GDSC2 4.2075 6.9316 2.1911 4.9553
HCC78 GDSC2 4.2164 14.9358 -1.7574 24.6324
NCI-H1563 GDSC2 4.2414 11.3795 0.0315 17.1851
NCI-H290 GDSC2 4.2424 8.1737 1.6138 8.3737
NCI-H2347 GDSC2 4.258 7.3821 2.0091 5.9457
SBC-3 GDSC2 4.2594 8.0784 1.6724 7.9803
CAL-12T GDSC2 4.2745 13.4029 -0.9483 21.4839
NCI-H3255 GDSC2 4.2769 14.7965 -1.6402 24.0741
Ms-1 GDSC2 4.2804 7.083 2.1677 4.9436
NCI-H2731 GDSC2 4.2994 9.981 0.7678 13.1682
NCI-H2029 GDSC2 4.3179 16.9506 -2.6812 27.2169
LC-2/ad GDSC1 4.3245 7.6093 3.0441 16.8151
EMC-BAC-2 GDSC1 4.3495 7.519 3.1115 16.2128
NCI-H2810 GDSC2 4.3557 8.6484 1.4633 9.0106
COR-L88 GDSC2 4.3596 6.6142 2.4392 3.1947
NCI-H1437 GDSC1 4.3637 8.5656 2.6072 19.7251
A-549 GDSC1 4.3693 11.7243 1.0405 28.2213
Lu-135 GDSC1 4.3892 8.0926 2.8644 17.8391
NCI-H1688 GDSC2 4.3948 10.8086 0.4308 14.7526
NCI-H1623 GDSC2 4.396 8.6057 1.5128 8.6228
NCI-H522 GDSC2 4.3963 8.5279 1.5508 8.3958
COLO 668 GDSC2 4.398 9.0014 1.3214 9.7519
NCI-H1869 GDSC2 4.4127 11.8632 -0.0773 17.2705
HCC15 GDSC2 4.4192 8.8775 1.397 9.2563
NCI-H2066 GDSC1 4.4199 8.3485 2.7651 18.4104
NCI-H2803 GDSC2 4.4365 8.2115 1.7322 7.2223
UMC-11 GDSC2 4.4424 9.4681 1.1253 10.7898
NCI-H1993 GDSC1 4.4521 14.0015 -0.0247 31.7558
NCI-H2135 GDSC2 4.4549 8.323 1.691 7.4275
NCI-H1437 GDSC2 4.4964 10.241 0.7857 12.5814
NCI-H1341 GDSC2 4.4993 9.3145 1.2412 9.9842
NCI-H1693 GDSC1 4.5009 6.9773 3.5165 12.5134
EMC-BAC-1 GDSC2 4.5202 11.8505 0.0105 16.5713
SW1573 GDSC2 4.533 12.8511 -0.4748 18.806
NCI-H1693 GDSC2 4.5424 7.2178 2.2728 3.8188
A-549 GDSC2 4.551 11.6739 0.1207 15.9499
NCI-H1304 GDSC1 4.5534 9.3019 2.4083 20.2499
NCI-H513 GDSC2 4.558 8.4799 1.6862 7.2329
NCI-H661 GDSC2 4.5602 8.782 1.5423 8.0793
NCI-H2009 GDSC1 4.5713 8.0638 3.0407 15.821
NCI-H2722 GDSC2 4.5742 8.9168 1.4869 8.3754
SW1271 GDSC2 4.5884 9.7984 1.0689 10.7697
Lu-165 GDSC2 4.5915 12.0544 -0.0367 16.6217
DMS 79 GDSC2 4.602 9.2556 1.3423 9.1602
NCI-H1963 GDSC2 4.6051 6.7987 2.5006 2.4461
NCI-H23 GDSC2 4.6078 8.5462 1.6882 7.1152
COR-L321 GDSC2 4.6111 6.9134 2.4528 2.695
NCI-H727 GDSC2 4.6376 9.8918 1.0584 10.7153
NCI-H1563 GDSC1 4.6434 14.189 0.0445 30.8566
NCI-H748 GDSC2 4.6596 6.9148 2.4797 2.4753
IA-LM GDSC2 4.6664 6.4186 2.6986 1.36
NCI-H2172 GDSC2 4.6669 7.6262 2.1607 4.2357
DMS 53 GDSC2 4.6739 6.756 2.5577 2.0462
NCI-H2804 GDSC2 4.6767 10.9292 0.5797 13.2681
LOU-NH91 GDSC2 4.68 11.5655 0.2699 14.8796
BEN GDSC2 4.7021 13.3263 -0.5818 18.853
NCI-H1793 GDSC1 4.7086 10.5463 1.9203 22.5654
NCI-H2804 GDSC1 4.7242 9.6721 2.3704 19.8146
NCI-H1876 GDSC1 4.7254 8.707 2.8535 16.5626
NCI-H1838 GDSC2 4.7277 9.3088 1.4036 8.5267
HOP-92 GDSC2 4.7291 12.5815 -0.1939 17.0306
NCI-H2141 GDSC2 4.7376 11.4814 0.3535 14.3111
HCC15 GDSC1 4.7472 9.746 2.3529 19.8358
NCI-H290 GDSC1 4.7886 8.3301 3.0957 14.5674
IST-SL1 GDSC2 4.8049 7.8668 2.1342 4.1412
NCI-H1435 GDSC2 4.8098 7.581 2.2674 3.3907
NCI-H23 GDSC1 4.8199 6.7868 3.8935 8.3114
NCI-H3122 GDSC1 4.8307 10.2867 2.1533 20.7433
NCI-H2595 GDSC2 4.8418 9.9157 1.1896 9.5095
HCC78 GDSC1 4.8433 8.1429 3.2356 13.318
NCI-H2795 GDSC1 4.8449 10.2177 2.1996 20.4098
Calu-3 GDSC2 4.8589 7.9406 2.133 4.0547
Lu-135 GDSC2 4.8653 6.9754 2.5645 1.7607
NCI-H2869 GDSC2 4.8778 8.8325 1.7303 6.3199
NCI-H1355 GDSC2 4.8782 8.6861 1.7994 5.9206
VMRC-LCD GDSC2 4.9007 7.439 2.3826 2.6322
HOP-62 GDSC2 4.9041 10.7198 0.8442 11.3051
NCI-H196 GDSC1 4.9136 13.1793 0.7763 27.2639
COR-L105 GDSC1 4.9218 8.7359 3.0048 14.7336
NCI-H2722 GDSC1 4.9303 10.5896 2.085 20.7728
NCI-H1792 GDSC2 4.948 11.7641 0.3673 13.7427
IST-SL1 GDSC1 4.9549 7.9253 3.4375 11.3718
NCI-H1105 GDSC2 4.9575 9.1655 1.6249 6.7712
NCI-H2291 GDSC1 4.9597 8.5251 3.1416 13.5907
NCI-H2227 GDSC2 4.9808 15.7839 -1.5864 22.1412
SK-LU-1 GDSC1 4.9851 8.3645 3.2428 12.7429
NCI-H2172 GDSC1 4.9972 8.3949 3.2376 12.7385
Calu-6 GDSC2 5.0046 6.9148 2.6587 1.1763
NCI-H1092 GDSC2 5.0138 6.6105 2.7837 0.6782
NCI-H2342 GDSC2 5.0371 12.2692 0.1846 14.4612
NCI-H810 GDSC2 5.1049 13.2943 -0.2677 16.4727
NCI-H226 GDSC1 5.1246 7.7484 3.6633 9.0322
SK-MES-1 GDSC2 5.1311 11.3671 0.689 11.6406
NCI-H3255 GDSC1 5.1511 9.5036 2.8088 15.3011
HOP-62 GDSC1 5.1512 7.5915 3.7624 8.1713
NCI-H1650 GDSC2 5.1673 11.3036 0.7446 11.2638
LC-1/sq GDSC2 5.177 11.1007 0.8488 10.6803
NCI-H841 GDSC1 5.1887 9.2215 2.9797 13.9581
NCI-H596 GDSC1 5.1957 10.4286 2.3829 17.9816
LB647-SCLC GDSC1 5.2044 10.2435 2.4823 17.3125
NCI-H1944 GDSC1 5.2161 8.6415 3.2906 11.5762
NCI-H1573 GDSC2 5.218 7.5291 2.5096 1.6105
NCI-H146 GDSC2 5.2242 11.4569 0.7098 11.3267
NCI-H1568 GDSC1 5.236 9.9488 2.6546 16.06
NCI-H841 GDSC2 5.242 16.0991 -1.5456 21.3822
NCI-H2818 GDSC2 5.2785 13.6519 -0.3171 16.2978
EBC-1 GDSC2 5.2896 14.0851 -0.5209 17.1838
RERF-LC-KJ GDSC2 5.3308 15.0622 -0.9698 18.9799
NCI-H1568 GDSC2 5.3372 13.8221 -0.3581 16.3501
Calu-3 GDSC1 5.3497 9.2403 3.0972 12.5597
BEN GDSC1 5.3512 8.2782 3.5757 8.9665
LK-2 GDSC2 5.3552 13.9602 -0.4126 16.5543
NCI-H2023 GDSC1 5.3576 11.8402 1.8083 20.8082
NCI-H2085 GDSC1 5.3601 8.7633 3.3421 10.7117
NCI-H838 GDSC1 5.3616 10.3775 2.5407 16.3843
NCI-H522 GDSC1 5.3736 9.8203 2.8274 14.4034
NCI-H1666 GDSC1 5.3759 9.29 3.0928 12.5051
NCI-H441 GDSC2 5.3792 9.2847 1.8305 4.8541
SW1573 GDSC1 5.3998 13.2194 1.1539 23.9476
NCI-H1694 GDSC1 5.4001 9.1852 3.1636 11.9081
NCI-H2731 GDSC1 5.4056 10.4641 2.5322 16.2903
NCI-H2227 GDSC1 5.4184 7.3798 4.0665 4.9884
ChaGo-K-1 GDSC1 5.4188 11.9974 1.7787 20.7596
NCI-H2591 GDSC1 5.4267 10.064 2.7477 14.775
ChaGo-K-1 GDSC2 5.434 13.6852 -0.2225 15.5125
NCI-H510A GDSC2 5.4412 7.1582 2.7548 0.5041
NCI-H2369 GDSC1 5.4592 7.472 4.0504 4.9969
NCI-H1915 GDSC2 5.4626 11.5946 0.8048 10.319
NCI-H2122 GDSC1 5.4717 6.9894 4.2903 3.157
NCI-H358 GDSC2 5.4738 15.943 -1.2974 19.9352
ABC-1 GDSC2 5.4864 13.3479 -0.0219 14.4547
NCI-H1651 GDSC2 5.5095 8.5202 2.2399 2.5349
LC-1/sq GDSC1 5.5202 8.6566 3.5153 8.9009
ABC-1 GDSC1 5.5289 9.7489 2.9827 12.799
NCI-H2803 GDSC1 5.5374 10.1239 2.8034 14.0274
NCI-H196 GDSC2 5.5482 14.0674 -0.3275 15.7394
COR-L279 GDSC1 5.575 7.9514 3.8991 5.8255
UMC-11 GDSC1 5.5775 7.1008 4.3058 2.7914
NCI-H524 GDSC1 5.6114 12.7603 1.5508 21.3157
PaCa-3 GDSC2 5.6201 16.2084 -1.3209 19.6964
DMS 114 GDSC2 5.637 13.2198 0.1442 13.3288
DMS 79 GDSC1 5.6639 11.3916 2.2718 17.0835
NCI-H2591 GDSC2 5.6771 13.6006 -0.0117 13.9933
SBC-3 GDSC1 5.6826 7.6189 4.13 3.821
HCC827 GDSC1 5.6832 8.9166 3.5064 8.4837
CPC-N GDSC1 5.6898 14.6128 0.69 25.0022
NCI-H847 GDSC1 5.6935 8.6158 3.66 7.3014
NCI-H2818 GDSC1 5.6958 11.22 2.3813 16.299
NCI-H740 GDSC2 5.6974 10.9023 1.281 7.2995
EMC-BAC-1 GDSC1 5.7128 11.6243 2.1939 17.3988
SK-LU-1 GDSC2 5.7244 8.0516 2.5343 1.0467
NCI-H1793 GDSC2 5.7287 13.6001 0.024 13.7139
NCI-H2347 GDSC1 5.7317 9.301 3.3535 9.4789
NCI-H510A GDSC1 5.7334 7.6363 4.1541 3.5263
NCI-H1792 GDSC1 5.7352 7.8108 4.0736 4.1071
EKVX GDSC1 5.7368 11.7985 2.126 17.7276
NCI-H1915 GDSC1 5.7415 7.359 4.2868 2.5675
NCI-H1573 GDSC1 5.7544 8.9441 3.5436 8.0024
NCI-H2405 GDSC1 5.7931 8.9575 3.5641 7.7411
NCI-H810 GDSC1 5.8241 8.9469 3.5908 7.4576
NCI-H1299 GDSC2 5.8483 12.1861 0.7769 9.7003
SW1271 GDSC1 5.8566 9.474 3.3582 9.0838
NCI-H2869 GDSC1 5.8591 8.0909 4.0212 4.1937
VMRC-LCD GDSC1 5.8594 7.5762 4.2576 2.5284
NCI-H1734 GDSC1 5.8604 8.1692 3.9854 4.4503
NCI-H2087 GDSC2 5.8619 8.2611 2.513 1.021
NCI-H1651 GDSC1 5.879 9.5382 3.3428 9.133
NCI-H650 GDSC1 5.888 7.4008 4.3515 1.8547
NCI-H1436 GDSC1 5.8903 14.1243 1.0899 22.6466
LK-2 GDSC1 5.8949 9.7973 3.2282 9.9209
NCI-H2444 GDSC1 5.9023 12.7929 1.7596 19.2766
COR-L95 GDSC1 5.9853 11.584 2.4189 15.1547
NCI-H1650 GDSC1 6.0039 10.6292 2.9004 11.9193
CAL-12T GDSC1 6.0117 11.7102 2.3763 15.3413
NCI-H1869 GDSC1 6.012 9.6055 3.4026 8.3308
NCI-H1963 GDSC1 6.099 8.3815 4.0338 3.5779
NCI-H1092 GDSC1 6.0995 11.5015 2.543 14.0207
COR-L321 GDSC1 6.1074 10.1946 3.1843 9.6394
NCI-H1838 GDSC1 6.1211 14.0415 1.3078 20.9122
NCI-H1666 GDSC2 6.1253 19.6 -2.6154 22.9541
NCI-H209 GDSC1 6.138 9.7815 3.4035 7.9906
NCI-H2081 GDSC1 6.1465 9.8025 3.3992 7.9993
SK-MES-1 GDSC1 6.1597 8.7385 3.9071 4.3308
RERF-LC-KJ GDSC1 6.1719 10.538 3.0632 10.3146
NCI-H358 GDSC1 6.1727 10.5832 3.0419 10.4609
NCI-H1435 GDSC1 6.1774 8.6599 3.9537 3.9688
NCI-H1355 GDSC1 6.2115 11.0899 2.8236 11.8473
LCLC-97TM1 GDSC1 6.249 8.8903 3.8914 4.2497
COR-L303 GDSC2 6.2502 18.7174 -2.0928 21.0641
NCI-H345 GDSC1 6.2523 13.3592 1.7429 18.2956
HCC366 GDSC1 6.262 9.3083 3.7069 5.5151
NCI-H2029 GDSC1 6.2974 9.4826 3.6479 5.8507
COR-L88 GDSC1 6.4127 11.2802 2.8711 10.9756
NCI-H650 GDSC2 6.4152 8.2021 2.7492 0.1799
IA-LM GDSC1 6.5328 7.9368 4.4394 0.6038
NCI-H2342 GDSC1 6.5344 13.853 1.707 17.6673
NCI-H2595 GDSC1 6.5574 10.9814 3.1104 8.9793
NCI-H1836 GDSC1 6.6208 8.0678 4.4265 0.5883
Lu-165 GDSC1 6.6335 8.5159 4.2578 1.3396
DMS 53 GDSC1 6.6602 8.3907 4.3196 1.0092
NCI-H2141 GDSC1 6.7019 12.8469 2.315 13.7455
NCI-H1299 GDSC1 6.7635 11.6713 2.9186 9.7578
NCI-H1781 GDSC1 6.8242 15.6573 1.0338 20.1716
NCI-H2228 GDSC1 6.8611 9.4118 3.9992 2.4693
NCI-H441 GDSC1 6.9409 11.6655 3.0349 8.5673
NCI-H2135 GDSC1 7.0547 8.6657 4.3794 0.477
NCI-H727 GDSC1 7.06 15.4163 1.3205 18.1902
NCI-H146 GDSC1 7.0982 8.9544 4.2903 0.7611
COLO 668 GDSC1 7.1049 8.8502 4.3317 0.6051
Calu-6 GDSC1 7.1577 9.4506 4.1249 1.4272
NCI-H1581 GDSC1 7.1889 8.8302 4.3717 0.4299
NCI-H322M GDSC1 7.2878 12.0071 3.09 7.4449
NCI-H211 GDSC1 7.3714 9.0592 4.3591 0.3805
Lu-65 GDSC1 7.3982 8.7237 4.4839 0.1204
SHP-77 GDSC1 7.4609 8.6585 4.5266 0.0625
KNS-62 GDSC1 7.6021 20.978 -1.0081 25.6345
NCI-H513 GDSC1 7.7319 9.4527 4.3535 0.262
NCI-H2087 GDSC1 7.7657 9.8238 4.2358 0.5405
Lu-139 GDSC1 7.9981 20.5656 -0.5197 23.2089
⏷ Show the Full List of 358 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 4.7819 7.3943 2.3353 3.0643
CBTCi002-A GDSC1 6.3758 8.8436 3.986 3.3566
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-140 GDSC1 0.573 5.4106 0.0306 53.0038
TE-4 GDSC1 1.0141 4.4322 0.7781 48.8506
KYSE-140 GDSC2 1.0792 7.0746 -0.6421 30.9128
OE21 GDSC2 1.4929 8.5643 -0.945 30.37
OE21 GDSC1 1.8708 7.2052 0.7715 41.8993
TE-8 GDSC1 2.4312 6.9038 1.4838 35.9176
EC-GI-10 GDSC1 2.5944 7.8469 1.2428 35.8854
TE-6 GDSC2 2.7198 9.1279 -0.0969 22.3055
TE-8 GDSC2 3.1943 10.1623 -0.2052 21.306
TE-10 GDSC1 3.2884 7.5591 2.0721 28.1088
KYSE-410 GDSC2 3.4784 6.5237 1.8495 8.8685
EC-GI-10 GDSC2 3.605 12.5285 -1.0476 23.7102
TE-4 GDSC2 3.6256 10.1797 0.1428 18.3208
TE-11 GDSC2 3.6757 10.4061 0.0702 18.5419
KYSE-180 GDSC1 3.7893 7.4188 2.6306 22.1389
KYSE-270 GDSC2 4.0253 9.7495 0.6739 14.3974
T.T GDSC2 4.0448 8.3459 1.384 10.2387
KYSE-520 GDSC2 4.0837 9.9222 0.6332 14.4671
OE33 GDSC2 4.1083 10.9773 0.1282 17.0564
KYSE-70 GDSC1 4.1234 13.9128 -0.2646 33.656
TE-9 GDSC1 4.1272 11.3408 1.0191 29.2917
KYSE-180 GDSC2 4.3514 10.5393 0.5311 14.3292
TE-10 GDSC2 4.3554 6.9267 2.2909 4.063
TE-5 GDSC2 4.3604 9.9782 0.8146 12.7548
KYSE-150 GDSC1 4.4458 15.7876 -0.9224 34.2022
COLO 680N GDSC2 4.4844 10.693 0.5547 13.8701
KYSE-450 GDSC2 4.4978 8.5739 1.5996 7.8779
KYSE-450 GDSC1 4.5314 7.8411 3.1162 15.4254
TE-11 GDSC1 4.5352 10.3551 1.8671 23.5463
KYSE-150 GDSC2 4.6937 11.0448 0.5355 13.4631
TE-9 GDSC2 4.7195 10.1824 0.9751 10.9973
TE-5 GDSC1 4.7414 16.8407 -1.1984 33.8881
T.T GDSC1 4.786 8.9534 2.782 16.8319
KYSE-510 GDSC1 5.0491 12.6696 1.1434 25.2125
TE-1 GDSC2 5.0649 10.554 1.0351 9.8968
KYSE-510 GDSC2 5.1709 15.0424 -1.0778 19.7817
KYSE-410 GDSC1 5.1802 6.6078 4.2721 4.0997
TE-15 GDSC1 5.4975 9.2327 3.2143 11.2215
TE-6 GDSC1 5.5169 8.2461 3.7144 7.3975
OE19 GDSC2 5.6282 19.3159 -2.8438 24.6623
OE19 GDSC1 5.7343 7.2406 4.3361 2.2427
KYSE-520 GDSC1 5.7541 10.0363 3.0094 11.9032
KYSE-70 GDSC2 5.8853 13.3721 0.2391 12.3488
KYSE-270 GDSC1 6.0111 12.4436 2.0145 17.5139
COLO 680N GDSC1 6.0181 10.2584 3.0911 10.5482
OE33 GDSC1 6.2348 8.2736 4.1589 2.4858
TE-1 GDSC1 8.3823 24.8416 -2.3333 27.3582
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 59 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EFO-27 GDSC1 -2.55 3.7498 -2.9468 74.1687
IGROV-1 GDSC2 -1.1025 6.1919 -2.509 46.4468
OVK18 GDSC1 -0.276 10.5325 -2.8786 55.6776
TOV-21G GDSC1 -0.2329 7.4966 -1.5738 57.2804
IGROV-1 GDSC1 0.3224 16.877 -5.2257 51.8943
A2780 GDSC1 0.71 6.9107 -0.3425 51.5004
A2780 GDSC2 0.8596 8.5294 -1.5387 34.9086
OVISE GDSC1 0.884 12.2168 -2.472 50.1055
EFO-27 GDSC2 1.2544 10.7926 -2.2507 35.2467
TOV-21G GDSC2 1.7928 6.9137 0.1338 24.5019
JHOS-4 GDSC2 1.8381 7.9489 -0.3205 26.48
OVK18 GDSC2 1.8747 12.4998 -2.5227 33.7458
OVTOKO GDSC1 2.328 8.2748 0.7806 38.9889
OVTOKO GDSC2 2.7683 8.1897 0.4125 19.5562
SK-OV-3 GDSC1 2.8313 10.5427 0.2155 37.8294
TYK-nu GDSC1 3.2429 7.813 1.9093 29.241
Caov-4 GDSC2 3.5414 7.2579 1.5337 10.6585
TOV-112D GDSC1 3.6218 8.1127 2.1382 26.0439
DOV13 GDSC2 3.7197 5.778 2.4076 4.7302
OVISE GDSC2 3.7658 9.3463 0.6712 15.117
OC 314 GDSC1 3.7925 10.6019 1.0846 30.4519
FU-OV-1 GDSC2 3.8618 9.4974 0.6718 14.8493
OV56 GDSC1 3.887 14.3415 -0.6852 35.5987
OC 314 GDSC2 3.9146 10.4809 0.2236 17.0966
OV-90 GDSC1 4.0431 10.2095 1.5053 27.4728
TOV-112D GDSC2 4.1889 7.5139 1.8971 6.7789
OVCAR-3 GDSC2 4.2617 7.7209 1.8479 6.9133
OVCAR-4 GDSC2 4.2731 7.196 2.1088 5.3123
ES-2 GDSC2 4.4599 6.8406 2.3962 3.2614
OVKATE GDSC2 4.5293 8.4275 1.6918 7.2612
JHOS-2 GDSC2 4.5455 8.9308 1.4602 8.596
OVCAR-5 GDSC1 4.5597 6.4512 3.8292 9.8447
OAW42 GDSC1 4.6393 10.3419 1.9633 22.5938
OV-90 GDSC2 4.682 8.7324 1.649 7.1896
SK-OV-3 GDSC2 4.7353 12.7237 -0.2594 17.3208
OAW28 GDSC2 4.7624 8.9807 1.5842 7.4009
Caov-3 GDSC2 4.894 9.7316 1.3137 8.689
DOV13 GDSC1 4.912 10.3999 2.1646 20.3675
EFO-21 GDSC2 5.0898 10.8784 0.8962 10.6101
RMG-I GDSC1 5.1112 8.1161 3.4692 10.5775
OVCAR-8 GDSC1 5.1197 7.8589 3.6042 9.5071
RMG-I GDSC2 5.13 11.5907 0.5802 12.2205
OVCAR-5 GDSC2 5.2635 11.2127 0.8538 10.4696
FU-OV-1 GDSC1 5.3108 9.5471 2.9142 14.0061
Kuramochi GDSC1 5.4696 7.8403 3.8786 6.2802
ES-2 GDSC1 5.4829 7.856 3.8805 6.2273
Kuramochi GDSC2 5.5144 15.4343 -1.0185 18.7582
JHOS-2 GDSC1 5.6247 10.7342 2.5677 15.3308
TYK-nu GDSC2 5.6276 14.712 -0.5847 16.7021
OVCAR-8 GDSC2 5.7425 10.5676 1.4624 6.2416
OAW42 GDSC2 5.8589 14.5729 -0.3553 15.1925
OV56 GDSC2 6.0638 15.4626 -0.6431 16.0178
OVCAR-4 GDSC1 6.1756 8.3494 4.0926 3.0266
OAW28 GDSC1 6.2497 10.5295 3.1207 9.7022
OVKATE GDSC1 6.2706 8.1594 4.2273 2.0008
EFO-21 GDSC1 6.3858 9.8454 3.5344 6.4466
OVCAR-3 GDSC1 6.4546 16.9038 0.1444 24.8237
JHOS-4 GDSC1 6.5907 9.83 3.6667 5.0787
Caov-4 GDSC1 7.7452 9.5671 4.3187 0.3326
⏷ Show the Full List of 59 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AsPC-1 GDSC1 2.7199 10.4109 0.172 38.4863
PaTu 8988t GDSC1 3.1899 11.4758 0.101 36.4563
KP-4 GDSC1 3.8803 9.8729 1.5238 28.1012
HPAF-II GDSC1 3.8863 9.2105 1.8549 26.3865
Capan-1 GDSC2 4.1544 6.3014 2.4557 3.4835
CFPAC-1 GDSC2 4.1611 7.153 2.0527 5.8947
KP-3 GDSC2 4.1645 11.4606 -0.0684 17.8757
SU.86.86 GDSC2 4.1743 6.0779 2.5729 2.7615
PaTu 8988t GDSC2 4.239 9.4475 0.9858 12.089
MIA PaCa-2 GDSC2 4.2588 6.2109 2.5635 2.6647
KP-1N GDSC2 4.2927 6.6247 2.3925 3.5883
DAN-G GDSC2 4.3504 11.2258 0.191 16.1052
Capan-2 GDSC2 4.3877 7.7945 1.8994 6.326
Hs 766T GDSC2 4.4123 11.3549 0.174 16.0324
BxPC-3 GDSC2 4.4382 8.0834 1.795 6.8429
YAPC GDSC2 4.4968 9.9225 0.9422 11.7054
PaTu 8902 GDSC1 4.5125 11.6595 1.1966 26.9767
PL4 GDSC2 4.5551 7.6106 2.0976 4.8099
MIA PaCa-2 GDSC1 4.6869 9.9239 2.2128 20.9398
HuP-T3 GDSC2 4.7298 10.1865 0.9804 10.944
HPAF-II GDSC2 4.76 10.9399 0.6348 12.7753
Panc 10.05 GDSC2 4.807 10.8492 0.7127 12.2449
HPAC GDSC2 4.8125 12.4481 -0.0664 16.2216
PSN1 GDSC2 4.8745 8.2339 2.0076 4.7348
HuP-T4 GDSC2 4.8887 8.3001 1.9858 4.8332
Panc 08.13 GDSC2 4.9098 7.6059 2.3138 2.9825
KP-4 GDSC2 5.1535 12.7916 0.0131 15.0342
KP-2 GDSC2 5.1707 6.4979 2.8892 0.2776
BxPC-3 GDSC1 5.1974 9.4684 2.8635 14.7551
MZ-PC-1 GDSC2 5.2197 8.356 2.1552 3.359
Hs 766T GDSC1 5.2602 9.8699 2.7133 15.5776
Panc 02.03 GDSC2 5.3509 8.6627 2.0928 3.4935
MZ-PC-1 GDSC1 5.3917 9.4879 3.0068 13.0744
AsPC-1 GDSC2 5.4034 12.8136 0.1789 13.6634
KP-2 GDSC1 5.406 7.3183 4.0875 4.8621
KP-3 GDSC1 5.4273 8.7212 3.4141 9.9537
DAN-G GDSC1 5.4454 10.528 2.5315 16.1601
SUIT-2 GDSC2 5.5632 7.2527 2.7684 0.4074
HuP-T3 GDSC1 5.5949 10.3526 2.734 14.3159
KP-1N GDSC1 5.6134 8.8032 3.5116 8.6498
QGP-1 GDSC2 5.6746 19.2352 -2.7692 24.3509
SUIT-2 GDSC1 5.742 8.6836 3.6611 7.1584
PSN1 GDSC1 5.7546 8.0548 3.971 4.8138
Panc 10.05 GDSC1 5.7736 15.701 0.2141 26.5636
SU.86.86 GDSC1 5.835 8.9819 3.5814 7.497
Panc 03.27 GDSC2 5.8895 16.8204 -1.4256 19.499
Capan-1 GDSC1 6.0102 7.9355 4.1832 2.737
SW1990 GDSC2 6.044 15.6261 -0.7358 16.4504
SW1990 GDSC1 6.2246 8.4348 4.0823 3.0025
Panc 03.27 GDSC1 6.3487 10.2886 3.3019 8.174
Panc 08.13 GDSC1 6.4511 12.0285 2.5364 13.0579
PaTu 8902 GDSC2 6.4564 16.4739 -0.8607 16.1215
HuP-T4 GDSC1 6.5103 9.5798 3.7328 4.7951
PL4 GDSC1 6.7662 8.4746 4.3332 0.851
HPAC GDSC1 6.7959 17.4701 0.1216 23.9721
YAPC GDSC1 6.9261 8.1627 4.509 0.192
QGP-1 GDSC1 6.954 8.4601 4.4147 0.4218
Capan-2 GDSC1 7.012 9.2698 4.1304 1.5568
CFPAC-1 GDSC1 7.0202 12.574 2.6591 10.8031
Panc 04.03 GDSC2 7.0769 16.3113 -0.3736 12.8867
Panc 02.03 GDSC1 8.4352 20.0217 0.0494 20.2414
Panc 04.03 GDSC1 9.6089 26.2736 -2.157 24.5295
⏷ Show the Full List of 62 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 GDSC2 3.2877 9.0173 0.4456 17.7368
NCI-H28 GDSC2 4.0259 7.5504 1.7618 7.9891
NCI-H28 GDSC1 4.1351 9.8226 1.7795 25.6856
IST-Mes1 GDSC2 4.4975 13.0192 -0.5853 19.3829
NCI-H2452 GDSC1 4.5012 8.2744 2.8742 17.3077
MPP 89 GDSC2 4.5981 16.5793 -2.2756 25.3447
MPP 89 GDSC1 4.8328 8.9793 2.8086 16.4673
NCI-H2052 GDSC1 5.0724 8.7515 3.1208 13.3396
MSTO-211H GDSC2 5.619 19.2923 -2.8391 24.6687
NCI-H2052 GDSC2 5.9085 15.7799 -0.9052 17.4369
IST-Mes1 GDSC1 5.9314 8.2577 3.9889 4.2594
MSTO-211H GDSC1 6.7346 8.6175 4.2636 1.1995
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2 -3.6651 0.2537 -3.7347 67.3802
LNCaP clone FGC GDSC1 -2.8828 1.8336 -2.9938 80.7581
VCaP GDSC2 3.4133 8.0043 1.0564 13.9107
22Rv1 GDSC2 3.906 9.3449 0.7823 14.112
NCI-H660 GDSC2 4.0681 8.4119 1.3689 10.271
DU145 GDSC1 4.0867 11.3415 0.9829 29.6083
VCaP GDSC1 4.2276 9.9808 1.7837 25.2673
DU145 GDSC2 4.5484 9.7969 1.041 11.0224
22Rv1 GDSC1 5.2089 10.1038 2.5556 16.8161
PC-3 GDSC1 5.9872 11.195 2.6114 13.9113
PC-3 GDSC2 6.464 17.9862 -1.5854 18.8839
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 1.749 10.8004 -0.9579 45.2695
A-253 GDSC2 4.7956 10.5848 0.8333 11.6115
Cancer Drug Sensitivity Data Curated from 113 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-3 GDSC2 1.4469 4.9095 0.6978 22.9245
CP50-MEL-B GDSC1 1.7227 4.9634 1.4163 41.1255
RVH-421 GDSC1 1.8833 8.446 0.2518 42.9049
LOX-IMVI GDSC2 1.967 7.6727 -0.065 24.8084
CP50-MEL-B GDSC2 2.112 6.2621 0.7525 19.9819
RPMI-7951 GDSC1 2.1339 5.8512 1.5788 37.4738
Hs 938.T GDSC2 2.2654 7.2064 0.4416 21.1343
A-388 GDSC2 2.3357 11.3989 -1.5653 29.4886
SK-MEL-31 GDSC2 2.3467 20.9562 -6.3205 38.6944
IGR-37 GDSC1 2.3973 5.0723 2.1212 33.0266
Mel Ho GDSC1 2.595 6.6447 1.7631 33.651
WM115 GDSC1 2.6984 5.3454 2.3641 29.7175
RVH-421 GDSC2 2.7136 9.2774 -0.1768 22.7064
RPMI-7951 GDSC2 2.7815 8.5097 0.2649 20.2912
A-431 GDSC2 2.7855 9.0836 -0.0173 21.7029
SK-MEL-3 GDSC1 2.8326 6.6482 2.0102 30.9677
HT-144 GDSC2 2.8623 5.2862 1.9346 10.2158
A2058 GDSC2 2.8842 6.8816 1.1653 14.8859
HT-144 GDSC1 2.8998 5.787 2.4259 28.1452
WM115 GDSC2 2.9505 8.3876 0.4733 18.6364
A101D GDSC2 3.0092 8.2119 0.6117 17.6913
IGR-1 GDSC1 3.0202 4.9765 2.8285 24.8347
CP66-MEL GDSC2 3.1577 9.0392 0.3253 18.7745
SK-MEL-28 GDSC2 3.2414 15.1589 -2.6638 29.9777
UACC-62 GDSC2 3.266 11.0746 -0.6011 22.872
A2058 GDSC1 3.3022 7.8324 1.959 28.664
Mel Ho GDSC2 3.314 8.4456 0.7535 15.9574
Hs 938.T GDSC1 3.3374 8.3487 1.7508 29.5742
SK-MEL-28 GDSC1 3.3416 7.2968 2.2457 26.8204
IGR-1 GDSC2 3.3568 5.033 2.4953 5.1333
Hs 940.T GDSC2 3.4112 8.3564 0.8787 14.9537
MZ-MEL-2 GDSC2 3.4374 8.75 0.7035 15.8734
SK-MEL-24 GDSC2 3.4394 7.796 1.182 13.0881
M14 GDSC2 3.4541 5.1524 2.5144 4.7414
WM278 GDSC2 3.4617 6.6022 1.7967 9.2459
A-375 GDSC1 3.5491 7.2948 2.4532 24.4755
WM35 GDSC2 3.5498 7.0264 1.656 9.8782
IST-MEL1 GDSC1 3.5784 8.7315 1.7996 28.1262
MMAc-SF GDSC1 3.6284 8.226 2.0903 26.2895
UACC-62 GDSC1 3.6459 6.7846 2.7848 21.7844
G-mel GDSC2 3.6586 6.4336 2.037 7.204
IGR-37 GDSC2 3.6975 6.645 1.9621 7.5721
WM793 GDSC2 3.7157 8.6917 0.9578 13.6291
G-mel GDSC1 3.7299 5.5657 3.3973 16.9939
WM278 GDSC1 3.7438 9.4285 1.6162 28.2724
MZ-MEL-7 GDSC2 3.8087 8.3392 1.2065 11.9145
WM793 GDSC1 3.8351 7.5786 2.5987 22.1356
WT2-iPS GDSC1 3.8574 6.8234 2.9774 19.4022
451Lu GDSC1 3.9365 5.5877 3.6072 14.4105
IST-MEL1 GDSC2 3.9556 11.8442 -0.4233 20.0995
COLO 800 GDSC2 3.9591 9.2047 0.8932 13.3409
MMAc-SF GDSC2 3.9675 8.1274 1.4337 10.1353
VMRC-MELG GDSC1 4.0406 10.6947 1.2627 28.6094
LB2518-MEL GDSC2 4.0717 7.2927 1.9215 6.9004
WT2-iPS GDSC2 4.1083 8.6471 1.2829 10.6829
SK-MEL-24 GDSC1 4.1519 6.5083 3.4143 14.8093
HMV-II GDSC2 4.2005 7.1836 2.0652 5.7316
COLO 679 GDSC1 4.2073 7.8703 2.8082 19.0125
SH-4 GDSC2 4.2734 6.8733 2.2628 4.3904
VMRC-MELG GDSC2 4.2752 10.8915 0.2993 15.7452
COLO 783 GDSC2 4.2783 9.2471 1.1137 11.2541
WM1552C GDSC2 4.3278 9.081 1.2316 10.4457
SK-MEL-30 GDSC2 4.3383 8.0227 1.7552 7.3015
A101D GDSC1 4.3411 6.6858 3.5109 13.2332
Mel JuSo GDSC2 4.3472 6.3017 2.5749 2.45
Mel JuSo GDSC1 4.3507 8.2602 2.7468 18.8268
MZ-MEL-7 GDSC1 4.3698 6.4461 3.654 12.011
LB373-MEL-D GDSC2 4.3778 7.77 1.9044 6.3175
COLO 829 GDSC2 4.3858 8.9437 1.3408 9.6662
COLO 792 GDSC2 4.4112 9.1214 1.2723 10.0089
COLO 679 GDSC2 4.4132 6.2729 2.6261 2.0662
M14 GDSC1 4.446 8.5519 2.6873 18.8393
COLO 792 GDSC1 4.4656 6.1334 3.8959 9.7291
CHL-1 GDSC2 4.4843 11.7618 0.0273 16.5796
WM1552C GDSC1 4.4985 8.5605 2.7295 18.3332
MeWo GDSC2 4.5091 7.6071 2.0695 5.064
SK-MEL-2 GDSC1 4.5328 7.0689 3.5002 12.5078
SK-MEL-31 GDSC1 4.5571 8.2284 2.9463 16.5641
IPC-298 GDSC1 4.6066 7.3021 3.4507 12.592
Hs 940.T GDSC1 4.607 7.3044 3.4498 12.5969
451Lu GDSC2 4.6618 8.6208 1.6888 6.9983
G-361 GDSC1 4.6757 7.107 3.6087 11.0954
UACC-257 GDSC2 4.7147 8.9192 1.5817 7.5157
SK-MEL-2 GDSC2 4.729 5.8002 2.9706 0.2657
UACC-257 GDSC1 4.7763 8.9023 2.7994 16.7478
SH-4 GDSC1 4.8482 6.2857 4.168 6.0431
MeWo GDSC1 4.9093 9.606 2.5593 17.8806
G-361 GDSC2 4.9272 10.0019 1.2065 9.2286
SK-MEL-5 GDSC1 4.9815 7.9932 3.4255 11.3684
WM35 GDSC1 5.0277 8.1561 3.3818 11.5384
SK-MEL-1 GDSC2 5.0509 6.3318 2.903 0.2938
A-375 GDSC2 5.0594 10.5181 1.0486 9.8337
SK-MEL-5 GDSC2 5.0868 13.6435 -0.4521 17.3512
GAK GDSC2 5.1117 6.5055 2.8636 0.368
LB373-MEL-D GDSC1 5.227 6.5776 4.3209 3.5832
HMV-II GDSC1 5.2273 8.0533 3.5921 9.2402
A-388 GDSC1 5.2732 15.1179 0.1034 28.5295
DJM-1 GDSC2 5.2931 19.3876 -3.1331 26.1786
CHL-1 GDSC1 5.3025 7.7108 3.8194 7.2394
GAK GDSC1 5.321 6.798 4.2802 3.6289
COLO 800 GDSC1 5.4964 8.1265 3.758 7.125
A-431 GDSC1 5.4997 13.1279 1.2794 23.0268
SK-MEL-1 GDSC1 5.5931 7.3819 4.1839 3.6428
COLO 829 GDSC1 5.6064 7.5877 4.095 4.2678
LB2518-MEL GDSC1 5.8358 8.2549 3.9293 4.9191
SK-MEL-30 GDSC1 6.0995 9.1045 3.6993 5.9513
CP66-MEL GDSC1 6.1706 10.8334 2.9193 11.3126
MZ-MEL-2 GDSC1 6.1956 8.2979 4.1267 2.7637
IPC-298 GDSC2 6.3989 16.8537 -1.083 17.1267
DJM-1 GDSC1 6.494 8.7847 4.0763 2.5708
LOX-IMVI GDSC1 7.2184 8.8436 4.3781 0.3975
EquiPSC Line K2 GDSC2 3.7491 12.6946 -1.0134 23.1678
EquiPSC Line K2 GDSC1 4.9971 7.3327 3.7683 8.6514
⏷ Show the Full List of 113 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 3.554 9.9151 0.2167 18.1505
HuTu 80 GDSC1 4.779 7.4825 3.511 11.4549
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Rh41 GDSC2 -1.2458 3.1118 -1.6071 46.4652
Rh41 GDSC1 -0.3727 3.091 -0.4797 63.446
Rh30 GDSC1 0.4159 5.8497 -0.2807 54.0974
KYM-1 GDSC1 0.8966 4.7034 0.5842 50.1055
G-401 GDSC2 1.0872 10.1219 -2.0821 35.4594
MES-SA GDSC1 1.1458 6.8427 0.1489 48.0666
Rh30 GDSC2 1.6906 6.857 0.0616 25.2605
GCT GDSC1 1.7261 4.8134 1.4607 40.9371
A-204 GDSC1 1.8062 9.7898 -0.4329 44.3912
SW982 GDSC1 2.287 6.4787 1.5052 36.7514
STS-0421 GDSC2 2.4237 6.1929 1.0831 16.9355
GCT GDSC2 2.8542 7.7852 0.6894 17.7545
G-402 GDSC1 2.8918 8.5056 1.2401 34.2221
SW872 GDSC1 3.0018 6.2927 2.3353 28.1218
HT-1080 GDSC1 3.0111 6.1186 2.4158 27.5724
SK-LMS-1 GDSC1 3.0866 7.5402 1.8787 30.238
VA-ES-BJ GDSC1 3.1959 9.0498 1.2805 32.4628
STS-0421 GDSC1 3.3531 8.3346 1.7727 29.3833
MFH-ino GDSC1 3.4456 8.0085 2.017 27.6104
Hs 633.T GDSC2 3.5324 8.0803 1.1158 13.2162
TE 441.T GDSC2 3.5427 10.6857 -0.1776 20.1324
MES-SA GDSC2 3.5475 8.4313 0.9527 14.1313
SW982 GDSC2 3.6058 9.7171 0.3577 17.2667
SW684 GDSC1 3.6132 9.4241 1.4966 29.4592
SW684 GDSC2 3.7254 9.7154 0.4549 16.4096
HT-1080 GDSC2 3.7828 5.993 2.3483 4.9465
RKN GDSC1 3.9012 9.82 1.569 27.788
G-402 GDSC2 3.9205 10.866 0.0364 18.0232
SK-LMS-1 GDSC2 4.1951 7.5196 1.8987 6.7554
VA-ES-BJ GDSC2 4.3313 11.0223 0.2772 15.7141
EW-8 GDSC1 4.5113 8.6927 2.675 18.6557
EW-8 GDSC2 4.5703 6.4971 2.6144 1.899
Hs 633.T GDSC1 4.5764 8.5374 2.8093 17.4623
MFH-ino GDSC2 4.5855 12.6951 -0.3578 18.1458
SW872 GDSC2 4.6802 12.2778 -0.0806 16.6133
A-204 GDSC2 4.805 11.8193 0.2369 14.7452
Rh18 GDSC1 4.806 10.8882 1.8318 22.6813
RKN GDSC2 4.905 9.8361 1.271 8.9095
SK-UT-1 GDSC2 5.0096 10.254 1.1415 9.42
SK-UT-1 GDSC1 5.2294 12.848 1.2018 24.3105
KYM-1 GDSC2 5.2827 13.9307 -0.4504 16.8881
G-401 GDSC1 5.4068 11.0611 2.2358 18.1619
RD GDSC2 5.5643 12.1872 0.59 11.2386
RD GDSC1 6.5108 12.141 2.5235 12.9753
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC1 -2.235 4.0908 -2.6805 72.1862
HGC-27 GDSC2 -0.7618 2.7071 -0.9832 41.7529
TMK-1 GDSC1 0.5001 7.5018 -0.7956 52.8268
HSC-39 GDSC1 0.6392 2.4471 0.6301 53.2937
23132/87 GDSC2 0.9259 6.2628 -0.4275 30.7121
IM95 GDSC1 0.9425 8.0095 -0.535 49.7542
23132/87 GDSC1 1.3503 7.4906 0.1073 46.6004
KATO III GDSC1 1.5712 6.3185 0.8028 43.9724
Fu97 GDSC1 1.6582 7.0836 0.5975 43.7384
Fu97 GDSC2 1.9225 8.7515 -0.6321 27.5025
NCI-N87 GDSC2 2.0917 8.8736 -0.5357 26.4772
TMK-1 GDSC2 2.2065 7.148 0.4151 21.4897
HSC-39 GDSC2 2.2448 4.997 1.4766 15.2349
IM95 GDSC2 2.6506 7.6836 0.5591 19.1535
AGS GDSC2 2.7472 8.6323 0.1738 20.8734
ECC10 GDSC1 2.9252 6.4708 2.1812 29.4743
OCUM-1 GDSC2 2.9467 8.8663 0.2311 19.9296
MKN45 GDSC2 3.0874 9.8402 -0.1347 21.3031
SNU-1 GDSC2 3.3729 5.6489 2.2006 6.9523
AGS GDSC1 3.4382 9.6046 1.2445 31.417
SNU-5 GDSC2 3.4755 6.6805 1.7688 9.3819
NCI-N87 GDSC1 3.4856 11.2491 0.4854 34.0054
SK-GT-2 GDSC2 3.6241 8.1756 1.1421 12.8019
SNU-16 GDSC2 3.6477 7.2869 1.604 9.9331
RERF-GC-1B GDSC2 3.6636 7.5678 1.4766 10.6736
ECC10 GDSC2 3.7371 6.6502 1.9898 7.2962
SCH GDSC2 3.9215 16.6042 -2.8264 28.6041
KATO III GDSC2 4.0047 12.1016 -0.5127 20.3643
SNU-5 GDSC1 4.0135 14.5759 -0.691 35.1515
SK-GT-2 GDSC1 4.1105 11.9468 0.7031 30.6014
RF-48 GDSC2 4.1175 8.1247 1.547 9.0757
TGBC11TKB GDSC2 4.1583 8.0364 1.6202 8.5343
ECC12 GDSC2 4.2017 10.6403 0.3676 15.5809
Hs 746.T GDSC2 4.238 11.2561 0.09 16.9042
MKN1 GDSC2 4.3553 12.9352 -0.653 20.0426
OCUM-1 GDSC1 4.3643 8.9717 2.4063 21.0405
MKN7 GDSC2 4.4437 10.6256 0.5576 13.9557
NUGC-3 GDSC2 4.5062 11.975 -0.0616 16.9569
SNU-16 GDSC1 4.7216 6.3837 4.0089 7.7828
SCH GDSC1 4.8445 9.2143 2.701 17.1694
MKN28 GDSC2 4.9254 13.1445 -0.3256 17.1637
GCIY GDSC2 4.9505 11.1664 0.6601 12.1988
MKN1 GDSC1 5.02 7.8086 3.5492 10.2781
GCIY GDSC1 5.3019 8.1931 3.5802 9.0889
NUGC-4 GDSC2 5.3989 7.2949 2.6858 0.7469
NUGC-3 GDSC1 5.4642 8.9286 3.3395 10.3978
RERF-GC-1B GDSC1 5.5709 10.277 2.7531 14.2635
MKN7 GDSC1 5.6713 10.5524 2.6931 14.3476
MKN45 GDSC1 6.1469 12.8459 1.9174 17.6518
TGBC11TKB GDSC1 6.4288 10.3746 3.3135 7.8936
RF-48 GDSC1 6.7552 16.0287 0.8011 21.3886
SNU-1 GDSC1 6.7674 8.8019 4.205 1.4561
Hs 746.T GDSC1 7.339 13.999 2.1929 12.839
NUGC-4 GDSC1 7.6534 9.0189 4.4724 0.093
MKN28 GDSC1 7.9015 9.6107 4.3595 0.2048
SNG-M GDSC1 3.2887 12.9445 -0.529 37.563
SNG-M GDSC2 3.5099 6.6976 1.7881 9.1656
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC1 -0.9443 2.8387 -1.0557 68.4166
FTC-133 GDSC2 2.2173 10.6679 -1.3079 29.0172
FTC-133 GDSC1 2.6095 11.5632 -0.4871 40.4297
K5 GDSC2 2.6477 7.4168 0.6886 18.4434
CGTH-W-1 GDSC1 3.4796 5.9678 2.9709 21.3318
KMH-2 GDSC2 3.6265 9.2528 0.6064 15.8667
B-CPAP GDSC2 3.7738 8.4265 1.1358 12.4278
8305C GDSC2 3.7828 7.221 1.7419 8.7215
CAL-62 GDSC2 3.7966 6.0926 2.3095 5.1544
WRO GDSC1 3.9791 10.6762 1.2167 29.0769
ASH-3 GDSC2 4.0832 8.1752 1.4968 9.4631
TT GDSC2 4.2142 8.4357 1.4651 9.3349
IHH-4 GDSC2 4.2199 9.2621 1.063 11.6926
BHT-101 GDSC1 4.2354 8.1751 2.6842 19.7496
HTC-C3 GDSC1 4.3837 9.9247 1.9497 23.7036
KMH-2 GDSC1 4.4147 7.9407 2.9626 17.0294
BHT-101 GDSC2 4.4526 10.3312 0.7091 13.1107
B-CPAP GDSC1 4.4585 7.5455 3.1975 15.1172
TT GDSC1 4.4879 8.1444 2.927 16.9837
HTC-C3 GDSC2 4.8126 8.9242 1.6444 6.9473
CGTH-W-1 GDSC2 4.8883 7.2389 2.4633 2.2334
8305C GDSC1 4.8981 6.6758 4.0151 7.0645
ML-1 [Human leukemia] GDSC2 5.0425 12.4957 0.078 14.9755
IHH-4 GDSC1 5.0856 11.8529 1.5817 22.9703
WRO GDSC2 5.1563 11.0519 0.8582 10.6738
8505C GDSC1 5.2823 10.8775 2.2284 18.6386
ML-1 [Human leukemia] GDSC1 5.3042 8.9484 3.2069 11.9049
ASH-3 GDSC1 5.3136 10.9041 2.2401 18.4572
TT2609-C02 GDSC1 5.4397 11.6357 1.9755 19.5903
CAL-62 GDSC1 5.5426 10.8363 2.4539 16.3381
8505C GDSC2 5.5777 11.5893 0.8831 9.669
TT2609-C02 GDSC2 6.1517 9.1762 2.2824 1.6625
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 80 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HO-1-u-1 GDSC2 -1.0373 3.5112 -1.4884 44.7911
DOK GDSC2 -0.1328 5.2593 -1.1104 38.3825
DOK GDSC1 0.5679 7.8261 -0.8535 52.2903
BB49-HNC GDSC2 0.5787 5.7133 -0.5463 32.803
HO-1-u-1 GDSC1 0.9439 8.1151 -0.5775 49.7471
OSC-20 GDSC1 1.2391 10.9476 -1.5313 48.2394
LB771-HNC GDSC1 1.339 5.7769 0.7451 45.9152
PCI-15A GDSC2 1.3979 5.4522 0.4134 24.6635
HSC-4 GDSC1 1.4894 11.787 -1.6754 47.0715
JHU-011 GDSC2 1.7932 7.6671 -0.2268 26.2278
Detroit 562 GDSC2 1.9081 8.2215 -0.387 26.5103
HSC-3 GDSC2 1.9369 6.1677 0.6273 21.3433
UPCI-SCC-090 GDSC1 1.9614 8.4058 0.3493 42.241
PCI-15A GDSC1 1.9741 5.3836 1.5644 38.662
PCI-38 GDSC1 2.0248 6.313 1.2906 39.3332
Detroit 562 GDSC1 2.1124 8.3497 0.5282 40.9355
UPCI-SCC-090 GDSC2 2.1399 6.3316 0.7461 19.9143
HSC-2 GDSC2 2.2312 6.0016 0.9917 18.1665
BB49-HNC GDSC1 2.5194 8.3682 0.9317 37.4121
BICR 10 GDSC1 2.5423 11.4684 -0.5055 40.7758
HO-1-N-1 GDSC1 2.5665 7.6453 1.304 35.8146
PCI-04B GDSC1 2.6004 8.4801 0.9619 36.8513
HO-1-N-1 GDSC2 2.7444 6.259 1.3482 14.2385
HSC-4 GDSC2 2.7927 10.7612 -0.8474 25.3755
CAL-33 GDSC1 2.9659 8.036 1.5309 32.5881
Ca9-22 GDSC1 3.0012 8.3254 1.432 32.8341
BICR 22 GDSC1 3.0062 12.0932 -0.3715 38.4129
SAT [Human HNSCC] GDSC1 3.0147 12.6448 -0.6335 38.9218
JHU-029 GDSC2 3.0656 16.1293 -3.2965 32.0091
HSC-3 GDSC1 3.0702 6.2147 2.4392 27.094
PCI-06A GDSC1 3.0981 8.5748 1.4105 32.4129
KOSC-2 GDSC2 3.1347 8.4451 0.6027 17.3485
KOSC-2 GDSC1 3.2486 11.7234 0.0342 36.3734
BICR 10 GDSC2 3.2851 9.8431 0.0306 19.8891
Ca9-22 GDSC2 3.3879 7.9661 1.0546 13.9957
FaDu GDSC1 3.4168 6.3735 2.7341 23.2959
SCC-25 GDSC1 3.5275 9.7355 1.2648 30.9056
SAS GDSC2 3.7483 8.7911 0.934 13.6766
JHU-011 GDSC1 3.7687 11.3043 0.7163 31.9788
CAL-27 GDSC2 3.8246 8.0575 1.3589 10.9579
OSC-20 GDSC2 3.9106 5.9042 2.4824 3.8282
PCI-06A GDSC2 3.9528 12.0148 -0.5106 20.4967
LB771-HNC GDSC2 3.9768 8.1309 1.439 10.0791
CAL-33 GDSC2 3.9871 8.4311 1.2983 10.8988
JHU-022 GDSC2 4.015 13.4031 -1.1533 22.9826
KON GDSC2 4.0714 15.2465 -2.0279 25.8964
SAT [Human HNSCC] GDSC2 4.1383 10.43 0.4232 15.4542
SKN-3 GDSC2 4.1465 8.2742 1.4949 9.3198
OSC-19 GDSC2 4.2131 10.7701 0.312 15.8406
BICR 31 GDSC2 4.2946 7.3093 2.069 5.5059
NCI-H3118 GDSC2 4.3242 7.5769 1.9607 6.0945
FaDu GDSC2 4.338 8.0743 1.73 7.4536
CAL-27 GDSC1 4.3505 7.9036 2.9228 17.5849
SCC-4 GDSC2 4.3997 7.6817 1.9616 5.928
BICR 78 GDSC2 4.4819 10.8246 0.488 14.2322
SCC-25 GDSC2 4.4947 7.2306 2.2371 4.1119
BICR 78 GDSC1 4.5151 9.2093 2.421 20.3237
SCC-4 GDSC1 4.5918 8.3643 2.9091 16.6928
JHU-029 GDSC1 4.7809 18.9113 -2.2006 35.7965
PCI-04B GDSC2 4.7884 10.4931 0.8728 11.4101
PCI-30 GDSC2 4.8061 12.7265 -0.2081 16.9086
BB30-HNC GDSC2 4.8425 13.6798 -0.6509 18.8068
BHY GDSC2 4.847 9.6283 1.3313 8.6877
JHU-022 GDSC1 4.8804 11.2126 1.732 22.9393
KON GDSC1 4.9826 8.1428 3.3516 11.9294
SCC-15 GDSC2 4.9963 7.7007 2.3202 2.8199
SAS GDSC1 5.0512 9.3266 2.8161 15.6069
PE/CA-PJ15 GDSC2 5.0553 8.2664 2.1013 3.9037
BB30-HNC GDSC1 5.068 15.5006 -0.2563 30.3537
NCI-H3118 GDSC1 5.1758 8.0632 3.5469 9.7605
BICR 22 GDSC2 5.2679 14.9762 -0.9737 19.1402
PCI-30 GDSC1 5.3802 14.0522 0.7224 25.8752
SKN-3 GDSC1 5.5276 8.3202 3.6858 7.5838
PE/CA-PJ15 GDSC1 5.6511 11.4021 2.2568 17.2175
OSC-19 GDSC1 5.7834 10.0897 3.0047 11.8471
SCC-15 GDSC1 5.7896 9.0798 3.5024 8.2092
SCC-9 GDSC1 5.795 12.4934 1.826 19.2555
HSC-2 GDSC1 5.9761 12.5157 1.9527 17.9756
SCC-9 GDSC2 6.746 19.7759 -2.2556 20.5956
BHY GDSC1 6.8577 15.2177 1.2731 18.962
⏷ Show the Full List of 80 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-29 GDSC1 0.4902 5.3842 -0.0515 53.7207
SW1710 GDSC1 1.2744 7.3685 0.0772 47.1651
RT-112 GDSC1 3.1177 9.188 1.1391 33.4327
KU-19-19 GDSC1 3.1187 13.3074 -0.8631 38.9386
SW1710 GDSC2 3.3096 8.7148 0.6152 16.7454
639V GDSC2 3.6221 7.7133 1.3711 11.4307
BFTC-905 GDSC2 3.9159 7.2708 1.818 7.9131
SW780 GDSC2 4.0357 6.6916 2.1885 5.3462
CAL-29 GDSC2 4.1612 10.1829 0.5633 14.6447
HT-1376 GDSC2 4.1816 7.363 1.9652 6.3809
RT-112 GDSC2 4.2308 10.9508 0.236 16.1862
UM-UC-3 GDSC2 4.4719 11.3668 0.2131 15.684
5637 GDSC2 4.5161 8.2759 1.7556 6.9102
J82 GDSC2 4.5871 7.7865 2.0354 5.1112
TCCSUP GDSC1 4.5912 13.7509 0.2191 30.4727
KU-19-19 GDSC2 4.6142 14.719 -1.3387 22.1312
J82 GDSC1 4.7582 11.8174 1.327 25.4326
SW780 GDSC1 4.7844 8.8602 2.8273 16.5207
HT-1197 GDSC1 4.8452 26.3926 -5.8874 40.2228
RT-4 GDSC2 4.9502 7.8647 2.2211 3.4186
TCCSUP GDSC2 5.0623 11.5722 0.5418 12.574
UM-UC-3 GDSC1 5.076 9.7878 2.6059 16.9562
5637 GDSC1 5.2178 8.3495 3.4374 10.4593
T24 GDSC1 5.2531 10.0637 2.611 16.2933
HT-1197 GDSC2 5.2547 17.3404 -2.1489 23.4025
BFTC-905 GDSC1 5.4306 7.7464 3.8965 6.2566
647V GDSC2 5.5611 13.9703 -0.2712 15.4548
639V GDSC1 5.6107 6.9744 4.3841 2.1644
T24 GDSC2 5.616 7.9929 2.5091 1.2298
647V GDSC1 5.7896 12.6228 1.7577 19.6456
HT-1376 GDSC1 6.5677 19.5262 -1.069 28.3546
RT-4 GDSC1 6.8872 9.0432 4.1636 1.5301
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ME-180 GDSC1 -3.2023 11.5359 -6.3424 64.4643
PA-1 GDSC1 -0.1321 3.6136 -0.3008 60.6123
SW954 GDSC1 0.5026 4.1114 0.2919 54.2331
C-33 A GDSC2 0.5545 5.8264 -0.6194 33.2052
DSH1 GDSC1 0.8487 3.4243 0.7774 50.681
PA-1 GDSC2 0.9058 6.7318 -0.6588 31.7374
SKN GDSC1 1.09 9.4081 -0.9845 48.8923
OMC-1 [Human cervical carcinoma] GDSC2 1.1352 6.4954 -0.3204 29.332
ME-180 GDSC2 1.5123 10.5549 -1.8948 33.3633
SW954 GDSC2 1.999 6.9413 0.3187 22.7667
BPH-1 GDSC1 2.0099 8.3311 0.4319 41.774
CAL-39 GDSC1 2.099 6.5753 1.2675 38.9047
CAL-39 GDSC2 2.1042 5.6558 1.0317 18.4054
ACC-OV7 GDSC2 2.6195 8.3142 0.2187 21.0712
SKN GDSC2 2.7066 7.9821 0.4611 19.4996
KGN GDSC2 2.8131 11.4473 -1.1723 26.5662
OMC-1 [Human cervical carcinoma] GDSC1 2.8741 7.0439 1.8836 31.3984
ACC-OV7 GDSC1 2.9994 8.7988 1.2086 33.772
C-33 A GDSC1 3.1091 9.1391 1.1542 33.417
NCC-IT GDSC2 3.2074 8.4645 0.6546 16.8357
DSH1 GDSC2 3.2673 6.5472 1.6635 10.6404
JAR GDSC1 3.2967 5.8025 2.844 23.1833
HEY GDSC1 3.4611 7.3478 2.3414 25.6225
Ca Ski GDSC1 3.5394 8.8093 1.7248 28.7
Ca Ski GDSC2 3.6072 10.92 -0.2421 20.2485
JAR GDSC2 3.6641 8.0391 1.242 12.0947
OVCA433 GDSC2 3.6764 11.9155 -0.6831 22.0187
NT2-D1 GDSC2 3.8014 8.8408 0.9512 13.4318
SW962 GDSC1 3.876 10.1187 1.3988 28.7102
LB831-BLC GDSC1 3.9269 9.9523 1.5272 27.8765
OVCA420 GDSC2 3.935 10.8561 0.0528 17.9025
PWR-1E GDSC1 3.9961 9.5736 1.7769 26.3078
NT2-D1 GDSC1 4.0132 8.4097 2.3645 22.8332
LB831-BLC GDSC2 4.0497 12.2201 -0.5362 20.3453
HeLa GDSC2 4.0539 10.2055 0.4695 15.4322
NEC8 GDSC2 4.117 6.667 2.2566 4.7527
PWR-1E GDSC2 4.1324 8.2743 1.4845 9.4169
BPH-1 GDSC2 4.1536 12.9051 -0.7954 21.1762
C-4-I GDSC2 4.1953 7.154 2.0759 5.6785
SKG-IIIa GDSC2 4.2063 8.9921 1.1858 11.0112
OVMIU GDSC1 4.2098 14.0525 -0.2591 33.3226
HEC-1 GDSC2 4.2314 8.2887 1.5497 8.7859
SiHa GDSC2 4.361 9.1988 1.198 10.5622
SW756 GDSC2 4.5109 9.4249 1.1956 10.2218
HEY GDSC2 4.596 9.2451 1.3432 9.1687
PEO1 GDSC2 4.6427 10.4491 0.7901 12.2062
MS751 GDSC2 4.6846 7.2038 2.3647 3.0593
DoTc2 4510 GDSC2 4.6975 8.8208 1.6172 7.3437
HEC-1 GDSC1 4.832 7.9004 3.3473 12.5138
OVMIU GDSC2 4.8494 13.1714 -0.3951 17.6629
OV17R GDSC2 4.8712 13.1568 -0.3716 17.5039
HT-3 GDSC2 4.8722 7.1552 2.491 2.1153
C-4-I GDSC1 5.1215 6.9229 4.0717 5.8492
JEG-3 GDSC2 5.1429 12.32 0.2354 13.9644
UWB1.289 GDSC2 5.1863 10.6034 1.0932 9.3192
OVCA433 GDSC1 5.2834 11.3315 2.0027 19.9739
SiSo GDSC2 5.3497 11.4177 0.8138 10.504
SKG-IIIa GDSC1 5.391 7.7348 3.8733 6.5523
TC-YIK GDSC1 5.4073 7.7521 3.8767 6.4779
SW962 GDSC2 5.408 7.7324 2.5175 1.3835
HeLa GDSC1 5.4283 7.2969 4.1136 4.6012
OVCA420 GDSC1 5.5283 7.8789 3.9015 5.9373
DoTc2 4510 GDSC1 5.6019 8.4366 3.6824 7.393
TC-YIK GDSC2 5.7472 19.765 -2.9763 24.7779
OV17R GDSC1 5.8279 8.6056 3.7574 6.2094
NEC8 GDSC1 5.8552 12.8201 1.7101 19.6923
JHOS-3 GDSC2 5.9042 17.3219 -1.6601 20.3167
JEG-3 GDSC1 6.0062 12.2159 2.1232 16.8953
SW756 GDSC1 6.0328 7.7418 4.2813 2.0529
SiHa GDSC1 6.0445 7.3301 4.4609 0.9781
HT-3 GDSC1 6.1497 8.1531 4.1651 2.5965
PEO1 GDSC1 6.2021 9.8332 3.4215 7.6961
UWB1.289 GDSC1 6.2681 12.4012 2.2247 15.5056
KGN GDSC1 6.3552 12.4908 2.2437 15.1388
SiSo GDSC1 6.4477 14.0066 1.5685 18.6413
JHOS-3 GDSC1 6.5268 12.6859 2.2707 14.4908
MS751 GDSC1 7.4335 9.219 4.3257 0.4436
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug

References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 218197
2 ClinicalTrials.gov (NCT03997123) Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC (CAPItello-290). U.S. National Institutes of Health.
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7709).
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 The novel AKT inhibitor afuresertib shows favorable safety, pharmacokinetics, and clinical activity in multiple myeloma. Blood. 2014 Oct 2;124(14):2190-5.
6 Inhibition of cholesterol metabolism underlies synergy between mTOR pathway inhibition and chloroquine in bladder cancer cells. Oncogene. 2016 Aug 25;35(34):4518-28. doi: 10.1038/onc.2015.511. Epub 2016 Feb 8.