Details of the Drug

General Information of Drug (ID: DMA5QPM)

• Drug Name: Zemaira
• Synonyms: Alpha-1-antitrypsin

Indication

Disease Entry	ICD 11	Status	REF
Emphysema	CA21	Approved	[1]

• Drug Type: Recombinant protein
• Cross-matching ID: TTD ID: D9EC0G

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Alpha-1-antitrypsin (SERPINA1)	TTA7UJC	A1AT_HUMAN	Inhibitor	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Emphysema
• ICD Disease Classification: CA21

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Alpha-1-antitrypsin (SERPINA1)	DTT	SERPINA1	7.84E-01	-0.08	-0.1
Alpha-1-antitrypsin (SERPINA1)	DTT	SERPINA1	1.32E-03	0.33	0.54

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services.