Details of the Drug

General Information of Drug (ID: DMAJ85O)

Drug Name

VDA-1102

Indication

Disease Entry	ICD 11	Status	REF
Actinic keratosis	EK90.0	Phase 2	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hexokinase-2 (HK2)	TTK02H8	HXK2_HUMAN	Modulator	[1]
Tissue kallikrein (KLK2)	TTJLNAW	KLK2_HUMAN	Modulator	[2]
Voltage-dependent anion channel (VDAC)	TTPZI04	NOUNIPROTAC	Modulator	[2]
Voltage-dependent anion-selective channel 1 (VDAC1)	TTAMKGB	VDAC1_HUMAN	Modulator	[1]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Actinic keratosis

ICD Disease Classification

EK90.0

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tissue kallikrein (KLK2)	DTT	KLK2	2.30E-01	-0.02	-0.2

Molecular Expression Atlas (MEA)

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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Clinical pipeline report, company report or official report of Vidac Pharma.