Details of the Drug

General Information of Drug (ID: DMAJV1J)

Drug Name

MGCD-290

Synonyms

MG-1; MG-3290; Histone deacetylase inhibitors (cardiovascular diseases), MethylGene; Histone deacetylase inhibitors (diabetes), MethylGene; Histone deacetylase inhibitors (fungal infection), MethylGene; Histone deacetylase inhibitors (inflammation), MethylGene; HDAC inhibitors (non-oncology), MethylGene; Histone deacetylase inhibitors (non-oncology), MethylGene

Indication

Disease Entry	ICD 11	Status	REF
Rheumatoid arthritis	FA20	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C17H25N3O2
Canonical SMILES: C1CC(=O)N(C1)CC(CN2CCN(CC2)C3=CC=CC=C3)O
InChI: 1S/C17H25N3O2/c21-16(14-20-8-4-7-17(20)22)13-18-9-11-19(12-10-18)15-5-2-1-3-6-15/h1-3,5-6,16,21H,4,7-14H2
InChIKey: AFBKGQPVUQUMRC-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 3035813
CAS Number: 148274-76-4
TTD ID: D0RF3F

References

1	ClinicalTrials.gov (NCT01497223) MGCD290 and Fluconazole Versus Fluconazole Alone for the Treatment of Moderate to Severe Vulvovaginal Candidiasis. U.S. National Institutes of Health.