Details of the Drug

General Information of Drug (ID: DMAJWLD)

Drug Name
5-(4-(4-Acetylphenyl)piperazin-1-ylsulfonyl)-6-chloroindolin-2-one
Indication
Disease Entry ICD 11 Status REF
Pompe disease 5C51.3 Preclinical [1]
Drug Type
Small molecular drug
Cross-matching ID
TTD ID
DW68KF

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lysosomal alpha-glucosidase (GAA) TTLPC70 LYAG_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Discovery of a novel noniminosugar acid alpha glucosidase chaperone series. J Med Chem. 2012 Sep 13;55(17):7546-59.
2 5-(4-(4-Acetylphenyl)piperazin-1-ylsulfonyl)indolin-2-one Analogs as Inhibitors of Acid alpha-Glucosidase for Potential Chaperone Treatment of Pompe Disease or Intervention for Diabetes Mellitus Type 2. N.A.. N.A.