General Information of Drug (ID: DMALFKX)

Drug Name
Savolitinib
Synonyms
1313725-88-0; AZD-6094; AZD6094; UNII-2A2DA6857R; CHEMBL3334567; 2A2DA6857R; Savolitinib [INN]; Volitinib(Savolitinib); Savolitinib [USAN:INN]; GTPL9918; SCHEMBL12489208; EX-A845; BDBM50023342; ZINC149738712; AKOS030526403; DB12048; compound 28 [PMID: 25148209]; HY-15959; AS-35250; 1H-1,2,3-Triazolo(4,5-b)pyrazine, 1-((1S)-1-imidazo(1,2-a)pyridin-6-ylethyl)-6-(1-methyl-1H-pyrazol-4-yl)-; KB-333895; FT-0700162; J-690125; 4-{1-[(1S)-1-{imidazo[1,2-a]pyri
Indication
Disease Entry ICD 11 Status REF
Renal cell carcinoma 2C90 Phase 3 [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [2]
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 345.4
Logarithm of the Partition Coefficient (xlogp) 1.5
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C17H15N9
IUPAC Name
3-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine
Canonical SMILES
C[C@@H](C1=CN2C=CN=C2C=C1)N3C4=NC(=CN=C4N=N3)C5=CN(N=C5)C
InChI
InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H,1-2H3/t11-/m0/s1
InChIKey
XYDNMOZJKOGZLS-NSHDSACASA-N
Cross-matching ID
PubChem CID
68289010
CAS Number
1313725-88-0
UNII
2A2DA6857R
DrugBank ID
DB12048
TTD ID
D0LW0T
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Proto-oncogene c-Met (MET) TTNDSF4 MET_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Hepatocyte growth factor receptor (MET) OT7K55MU MET_HUMAN Post-Translational Modifications [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Renal cell carcinoma
ICD Disease Classification 2C90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Proto-oncogene c-Met (MET) DTT MET 1.08E-03 -0.24 -0.4
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 2.8959 5.1293 -0.7336 0.5741
RPMI-3460/CS1 GDSC1 4.0061 5.8772 0.7137 0.4457
EW-11 GDSC1 -1.7884 2.6384 -2.505 41.6232
HuO-3N1 GDSC2 0.8953 4.4806 -1.5451 7.4455
CADO-ES1 GDSC2 1.1306 6.9879 -2.6023 13.0534
EW-1 GDSC2 1.3253 4.7053 -1.3611 5.4304
EW-12 GDSC2 1.3574 3.4887 -0.7852 2.1466
TC-71 GDSC2 1.5105 3.4549 -0.6902 1.4804
A-673 GDSC2 1.5379 2.7751 -0.4083 0.3565
EW-7 GDSC2 1.6961 4.1103 -0.8731 2.1343
SK-PN-DW GDSC2 1.7068 3.86 -0.7615 1.5876
HOS GDSC2 1.7486 3.2813 -0.5114 0.5487
EW-11 GDSC2 1.8472 4.9004 -1.1358 3.271
ES1 GDSC2 1.8635 3.5433 -0.5626 0.6426
EW-24 GDSC2 1.8835 3.2789 -0.4564 0.3202
CHSA8926 GDSC2 1.9198 13.1096 -5.0317 21.9652
NOS-1 [Human HNSCC] GDSC2 1.9369 9.1239 -3.0659 13.6001
SK-ES-1 GDSC2 1.9374 3.8062 -0.632 0.8328
HuO9 GDSC2 1.9507 5.5139 -1.351 4.2633
MHH-ES-1 GDSC1 1.9985 3.7086 0.6343 3.4065
EW-16 GDSC2 2.0001 4.353 -0.8219 1.5435
CAL-72 GDSC1 2.0654 4.4246 0.3379 5.441
CAL-72 GDSC2 2.0675 3.4617 -0.4519 0.2402
MG-63 GDSC2 2.1093 3.8012 -0.5582 0.4838
HuO9 GDSC1 2.124 5.3731 -0.0804 8.423
ES8 GDSC2 2.1961 3.8814 -0.5532 0.4274
SJSA-1 GDSC2 2.2592 4.0264 -0.5814 0.4723
EW-18 GDSC2 2.2809 4.3608 -0.6977 0.8172
CADO-ES1 GDSC1 2.2922 4.5294 0.4367 4.1488
SaOS-2 GDSC2 2.2939 4.3475 -0.6872 0.7732
MHH-ES-1 GDSC2 2.3067 4.0383 -0.5671 0.4126
ES6 GDSC2 2.3399 4.362 -0.6734 0.6993
CAL-78 GDSC2 2.3807 4.13 -0.5716 0.3919
CHSA0011 GDSC2 2.399 5.0154 -0.9022 1.4955
EW-13 GDSC2 2.4065 4.4919 -0.6947 0.726
ES4 GDSC2 2.4962 6.214 -1.3561 3.4868
U2OS GDSC2 2.6489 4.4945 -0.6 0.3525
U-CH2 GDSC2 2.6743 4.308 -0.5255 0.2018
EW-22 GDSC2 2.6778 4.6219 -0.6345 0.4204
NY GDSC2 2.7264 4.9026 -0.7176 0.6144
ES7 GDSC2 2.7496 5.2206 -0.8272 0.9384
EW-24 GDSC1 2.865 4.9307 0.5833 2.0807
SK-ES-1 GDSC1 2.924 4.7508 0.6872 1.4124
EW-3 GDSC2 2.9366 5.1139 -0.7121 0.5007
ES1 GDSC1 2.9403 4.684 0.7218 1.2136
NOS-1 [Human HNSCC] GDSC1 3.0027 7.0982 -0.3145 7.8081
SK-PN-DW GDSC1 3.0108 5.7239 0.318 3.496
ES7 GDSC1 3.0676 5.981 0.2361 3.9254
G-292 clone A141B1 GDSC2 3.0742 5.0969 -0.6543 0.3218
EW-1 GDSC1 3.0928 5.1299 0.6131 1.6001
TC-71 GDSC1 3.1403 5.7612 0.3718 2.9334
MG-63 GDSC1 3.1487 14.7257 -3.9251 25.735
ES5 GDSC2 3.2004 5.773 -0.849 0.7398
CHSA0108 GDSC2 3.2854 5.3737 -0.6736 0.296
ES5 GDSC1 3.3059 6.5677 0.1097 4.3071
ES6 GDSC1 3.3804 6.5021 0.1794 3.7313
HOS GDSC1 3.3945 4.94 0.8161 0.4501
CHSA0108 GDSC1 3.4338 13.6337 -3.1749 22.2857
H-EMC-SS GDSC2 3.4423 5.6567 -0.715 0.327
EW-18 GDSC1 3.4462 5.8996 0.4677 1.9392
SJSA-1 GDSC1 3.451 5.3896 0.6717 0.9456
CHSA8926 GDSC1 3.4715 16.6484 -4.6319 27.0573
EW-3 GDSC1 3.5056 6.0538 0.433 2.0511
CHSA0011 GDSC1 3.6635 7.421 -0.0681 4.793
G-292 clone A141B1 GDSC1 3.7134 5.4496 0.7553 0.4677
SaOS-2 GDSC1 3.7245 5.444 0.7615 0.4438
NY GDSC1 3.7483 6.8338 0.229 2.8602
A-673 GDSC1 3.7493 5.4874 0.7554 0.4493
ES8 GDSC1 3.7493 5.7007 0.6779 0.6991
HuO-3N1 GDSC1 3.7581 6.1448 0.5128 1.3691
EW-7 GDSC1 3.8238 5.5612 0.7573 0.4091
EW-13 GDSC1 3.8591 5.7132 0.7164 0.509
ES4 GDSC1 3.9283 7.8189 -0.0978 4.5173
EW-16 GDSC1 3.9747 6.3629 0.5222 1.134
U2OS GDSC1 4.1673 6.2006 0.6594 0.5224
EW-22 GDSC1 4.24 6.1991 0.6872 0.4146
H-EMC-SS GDSC1 4.4291 6.5164 0.6456 0.4425
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 315 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 2.3329 3.7204 -0.4455 0.1556
JM1 GDSC1 2.9861 4.7914 0.6999 1.2728
MV4-11 GDSC1 0.2306 20.0788 -8.9808 42.1438
ST486 GDSC2 0.3747 5.725 -2.5565 14.7823
SU-DHL-5 GDSC2 0.491 3.4728 -1.3461 7.1916
P32/ISH GDSC2 0.5437 2.2326 -0.7021 3.0912
MV4-11 GDSC2 0.5644 2.5363 -0.8342 3.8489
SUP-M2 GDSC2 0.5809 8.9118 -3.9815 21.2832
Karpas-231 GDSC2 0.5877 2.6074 -0.8523 3.9082
MHH-CALL-2 GDSC2 0.688 4.3601 -1.6366 8.4967
DEL GDSC2 0.6897 10.0072 -4.4411 22.8599
RC-K8 GDSC2 0.6979 2.7649 -0.853 3.6771
JJN-3 GDSC2 0.7051 3.0685 -0.9938 4.5132
YT GDSC2 0.7237 2.7543 -0.8307 3.4901
SU-DHL-10 GDSC2 0.7667 2.1692 -0.5319 1.6846
OCI-M1 GDSC2 0.7958 3.6029 -1.1891 5.5027
CESS GDSC2 0.8381 3.6106 -1.1635 5.2549
HL-60 GDSC2 0.8464 3.0546 -0.8926 3.6122
KMS-12-BM GDSC2 0.8513 3.7909 -1.2415 5.6991
KE-37 GDSC2 0.859 7.8372 -3.2277 17.0334
JVM-2 GDSC2 0.8739 3.7431 -1.2028 5.4155
A3/Kawakami GDSC2 0.8752 4.333 -1.4875 7.142
SU-DHL-6 GDSC2 0.8861 2.7884 -0.7431 2.6669
ALL-SIL GDSC2 0.9201 7.197 -2.8634 14.9967
Jurkat GDSC2 0.9559 5.958 -2.2248 11.3512
BALL-1 GDSC2 0.9773 4.6981 -1.5928 7.5466
TUR GDSC2 1.0083 4.0302 -1.2494 5.4101
KCL-22 GDSC2 1.0187 3.9631 -1.2104 5.1549
P30/OHK GDSC2 1.0218 3.5921 -1.0326 4.0944
Hs 445 GDSC2 1.033 2.9173 -0.7142 2.2568
A4/Fukuda GDSC2 1.0541 3.0974 -0.7834 2.6042
EM-2 GDSC2 1.0542 6.6071 -2.4714 12.5148
Ramos.2G6.4C10 GDSC2 1.0654 2.8672 -0.6732 1.9844
SU-DHL-1 GDSC2 1.0684 6.7854 -2.5487 12.9111
RPMI-6666 GDSC2 1.0697 6.8492 -2.5791 13.076
HH [Human lymphoma] GDSC2 1.0725 4.0013 -1.193 4.9414
EJM GDSC2 1.1087 5.2385 -1.7627 8.2673
Mono-Mac-6 GDSC2 1.1115 5.6747 -1.9728 9.5059
EB2 GDSC2 1.1119 8.0932 -3.1615 16.046
OPM-2 GDSC2 1.1561 2.8416 -0.6123 1.5404
GA-10 GDSC2 1.1608 3.5284 -0.9163 3.1687
P12-Ichikawa GDSC2 1.1639 3.8349 -1.056 3.9616
OCI-AML-2 GDSC2 1.1653 2.6851 -0.5408 1.1811
Karpas-45 GDSC2 1.1904 3.0305 -0.6759 1.8171
SIG-M5 GDSC2 1.2364 2.2182 -0.3236 0.2733
L-363 GDSC2 1.2485 3.8929 -1.0306 3.6625
MM1.S GDSC2 1.2558 3.8758 -1.0182 3.5794
MC116 GDSC2 1.2586 2.0313 -0.2487 0.0972
Karpas-1106P GDSC2 1.2735 4.7799 -1.4301 5.9387
MOLT-16 GDSC2 1.2891 3.4806 -0.8196 2.4282
IM-9 GDSC2 1.2969 3.9711 -1.0371 3.6146
WSU-NHL GDSC2 1.2979 3.482 -0.8153 2.3916
MOLT-4 GDSC2 1.3161 8.4525 -3.1858 15.657
LP-1 GDSC2 1.3456 5.4194 -1.6869 7.3024
JSC-1 GDSC2 1.3496 4.0248 -1.0299 3.4837
Raji GDSC2 1.3544 3.0391 -0.5944 1.2143
Karpas-620 GDSC2 1.3545 2.8629 -0.522 0.8967
MHH-PREB-1 GDSC2 1.3557 9.8915 -3.8663 18.7503
PF-382 GDSC2 1.3577 3.9545 -0.9931 3.2649
MOLM-13 GDSC2 1.3653 7.693 -2.7765 13.4257
DB GDSC2 1.3893 4.1357 -1.0568 3.5666
AMO1 GDSC2 1.3913 3.7646 -0.8883 2.64
QIMR-WIL GDSC2 1.3947 5.8034 -1.8377 8.0811
Karpas-299 GDSC2 1.4346 3.3189 -0.6713 1.4802
L-1236 GDSC2 1.4347 4.7995 -1.3355 5.072
SUP-B15 GDSC2 1.4454 8.3469 -3.0387 14.6
Daudi GDSC2 1.4615 3.3152 -0.6562 1.3786
HT GDSC2 1.4725 2.9329 -0.496 0.6908
L-540 GDSC2 1.4817 3.226 -0.6094 1.1455
WIL2 NS GDSC2 1.4824 3.961 -0.9241 2.6939
TK [Human B-cell lymphoma] GDSC2 1.4828 3.0087 -0.5213 0.7787
CTV-1 GDSC2 1.489 3.9414 -0.9118 2.6186
ME1 GDSC2 1.4935 2.6415 -0.3769 0.2924
RCH-ACV GDSC2 1.496 3.6136 -0.7651 1.8579
CCRF-CEM GDSC2 1.501 3.6337 -0.7711 1.881
BV-173 GDSC2 1.5052 3.8326 -0.8549 2.2988
697 GDSC2 1.5118 3.0579 -0.5276 0.7792
HC-1 GDSC2 1.5228 6.2405 -1.9606 8.5199
ATN-1 GDSC2 1.5266 3.7082 -0.7896 1.9397
BL-41 GDSC2 1.535 2.8598 -0.4411 0.4566
HAL-01 GDSC2 1.537 3.8118 -0.8287 2.1219
SUP-T1 GDSC2 1.5633 3.3298 -0.6128 1.0787
Farage GDSC2 1.5783 6.8851 -2.2325 9.9495
OCI-Ly7 GDSC2 1.5875 3.0458 -0.4897 0.5828
MOLP-8 GDSC2 1.6181 3.0343 -0.4724 0.5052
NOMO-1 GDSC1 1.6185 15.6118 -5.5774 34.2083
Jiyoye GDSC2 1.6237 12.9316 -5.1675 23.1241
RS4;11 GDSC2 1.6386 9.1083 -3.2713 15.3012
NCI-H929 GDSC2 1.6461 21.0917 -9.2074 32.5059
K-562 GDSC2 1.649 3.604 -0.6839 1.2998
LAMA-84 GDSC2 1.6521 8.5836 -3.005 13.94
GR-ST GDSC2 1.665 4.4132 -1.0221 2.941
OCI-AML-3 GDSC2 1.6745 3.8515 -0.7742 1.6835
SU-DHL-8 GDSC2 1.6748 3.2422 -0.5278 0.6535
SUP-HD1 GDSC2 1.6839 6.4086 -1.933 8.026
SCC-3 GDSC2 1.7103 3.018 -0.4291 0.3283
Granta-519 GDSC2 1.722 4.0026 -0.8138 1.8146
ML-2 GDSC2 1.7223 3.3436 -0.5464 0.6849
U-698-M GDSC2 1.7323 3.6171 -0.6497 1.0727
NB4 GDSC2 1.7572 2.8793 -0.3621 0.1616
SKM-1 GDSC2 1.7599 3.2217 -0.4843 0.4578
MOLM-16 GDSC2 1.7734 3.3328 -0.5205 0.5626
NU-DUL-1 GDSC2 1.7739 3.3973 -0.5449 0.6433
MEG-01 GDSC2 1.777 4.0791 -0.8182 1.7706
KG-1 GDSC2 1.8204 5.0803 -1.2313 3.8223
RL GDSC2 1.8391 3.7122 -0.6388 0.936
Kasumi-1 GDSC2 1.8442 3.6834 -0.6252 0.8802
KM-H2 GDSC2 1.8501 5.8532 -1.5661 5.6235
DoHH2 GDSC2 1.8542 4.523 -0.9672 2.3958
CML-T1 GDSC2 1.885 3.3522 -0.4824 0.3869
JeKo-1 GDSC2 1.8855 3.2408 -0.4419 0.2845
KY821 GDSC2 1.8863 3.5681 -0.5624 0.6271
MC116 GDSC1 1.8883 3.7551 0.5389 4.4003
EoL-1 GDSC2 1.8915 3.7233 -0.6199 0.8234
MOLT-13 GDSC2 1.8937 3.7679 -0.6364 0.8825
Karpas-422 GDSC2 1.9015 4.7447 -1.0378 2.6873
SU-DHL-16 GDSC2 1.9102 3.259 -0.439 0.2684
SR GDSC2 1.9364 3.6766 -0.5826 0.661
DG-75 GDSC2 1.9502 3.986 -0.697 1.0691
NK-92MI GDSC2 1.9603 3.8434 -0.6365 0.8317
U266B1 GDSC2 2.0171 3.8259 -0.6054 0.6836
A3/Kawakami GDSC1 2.0315 11.3503 -3.1139 26.0992
TALL-1 [Human adult T-ALL] GDSC2 2.0478 5.9226 -1.4788 4.801
DND-41 GDSC2 2.0483 3.6397 -0.5232 0.4176
RPMI-8226 GDSC2 2.0624 3.4999 -0.4673 0.2749
SU-DHL-4 GDSC2 2.0668 3.5878 -0.4971 0.3422
Reh GDSC2 2.0676 3.6667 -0.5254 0.4143
WSU-DLCL2 GDSC2 2.0857 3.2425 -0.3699 0.0996
ARH-77 GDSC2 2.0896 3.9567 -0.6246 0.6997
MY-M12 GDSC2 2.1053 5.1658 -1.1112 2.7838
DEL GDSC1 2.1081 6.2733 -0.533 11.7877
BC-3 GDSC2 2.1097 3.808 -0.5606 0.4903
NOMO-1 GDSC2 2.1103 3.6311 -0.496 0.3217
SU-DHL-5 GDSC1 2.1109 5.3605 -0.0836 8.4847
SUP-M2 GDSC1 2.1322 5.2606 -0.0198 7.9465
SK-MM-2 GDSC2 2.1388 3.8408 -0.561 0.4765
MLMA GDSC2 2.1415 11.7407 -4.1954 18.2855
ROS-50 GDSC2 2.1432 4.0923 -0.6536 0.7612
HDLM-2 GDSC2 2.1498 4.635 -0.8655 1.5807
L-428 GDSC2 2.1548 13.5185 -5.0583 21.5232
VAL GDSC2 2.1622 4.1366 -0.6625 0.7784
MOLT-16 GDSC1 2.1644 6.3562 -0.5323 11.6104
RL GDSC1 2.1788 6.1609 -0.4259 10.804
VL51 GDSC2 2.1822 4.4817 -0.7885 1.2304
Loucy GDSC2 2.217 4.245 -0.6806 0.8026
SKM-1 GDSC1 2.2232 3.8357 0.713 2.356
RPMI-8402 GDSC1 2.231 10.3389 -2.4532 22.6889
RPMI-8402 GDSC2 2.233 3.82 -0.5169 0.322
BE-13 GDSC2 2.2384 3.6814 -0.466 0.2146
Ku812 GDSC2 2.2556 4.2067 -0.6498 0.6762
WIL2 NS GDSC1 2.2573 4.4226 0.4645 4.0292
NB4 GDSC1 2.286 3.8925 0.7233 2.1666
Karpas-620 GDSC1 2.2921 8.5561 -1.5219 17.6501
SUP-T1 GDSC1 2.2948 5.2769 0.0847 6.7233
MN-60 GDSC2 2.3006 4.0416 -0.5706 0.4244
RC-K8 GDSC1 2.3026 6.5656 -0.5344 11.212
IM-9 GDSC1 2.3116 4.2043 0.5981 2.9645
CRO-AP2 GDSC2 2.325 4.145 -0.5988 0.4874
OCI-Ly19 GDSC2 2.3533 4.4915 -0.7169 0.8333
MN-60 GDSC1 2.3585 4.8406 0.3332 4.7409
OCI-M1 GDSC1 2.366 4.3669 0.5564 3.1407
SR GDSC1 2.3739 9.5425 -1.9479 19.7527
WSU-DLCL2 GDSC1 2.3744 3.6659 0.8674 1.1338
MHH-CALL-4 GDSC2 2.3779 4.2504 -0.6165 0.5097
Namalwa GDSC1 2.3783 5.1625 0.1945 5.7023
TUR GDSC1 2.3822 5.4984 0.0376 6.842
GDM-1 GDSC2 2.3851 4.5161 -0.7129 0.7985
CTB-1 GDSC2 2.3933 4.4333 -0.6781 0.682
JVM-3 GDSC2 2.4045 4.1296 -0.5624 0.3601
MHH-CALL-2 GDSC1 2.4054 5.0315 0.2737 5.061
MOLT-4 GDSC1 2.4101 9.1586 -1.7306 18.4683
KMOE-2 GDSC2 2.4153 4.6668 -0.7577 0.9303
KE-37 GDSC1 2.4314 4.385 0.5864 2.8048
HT GDSC1 2.4425 5.8159 -0.0737 7.4988
Farage GDSC1 2.4503 4.506 0.5429 3.0621
KOPN-8 GDSC2 2.4517 13.171 -4.6709 19.4645
BL-41 GDSC1 2.4642 4.1776 0.6961 2.0266
Namalwa GDSC2 2.4686 14.8026 -5.4583 22.1745
Sc-1 GDSC1 2.469 5.7789 -0.0383 7.1724
OCI-Ly19 GDSC1 2.4752 10.9726 -2.5792 22.5022
H9 GDSC2 2.4775 4.7219 -0.7522 0.8687
Karpas-299 GDSC1 2.4786 5.3434 0.174 5.6066
K-562 GDSC1 2.4824 6.8677 -0.5535 10.8273
LC4-1 GDSC2 2.4933 4.8241 -0.7847 0.9692
P30/OHK GDSC1 2.4978 5.0883 0.3052 4.6207
MOLM-16 GDSC1 2.4978 6.5141 -0.3716 9.5003
BONNA-12 GDSC2 2.4997 4.8337 -0.7856 0.9679
AMO1 GDSC1 2.5004 4.5907 0.5338 3.0253
NCI-H929 GDSC1 2.5153 4.9438 0.3824 4.0372
THP-1 GDSC2 2.525 4.0093 -0.4762 0.1595
Daudi GDSC1 2.5256 4.2867 0.6817 2.0145
BV-173 GDSC1 2.5449 5.7924 0.0053 6.6644
Kasumi-1 GDSC1 2.5602 5.8281 -0.0016 6.6763
TK [Human B-cell lymphoma] GDSC1 2.5695 4.4525 0.6334 2.2453
CA46 GDSC2 2.57 6.4114 -1.4021 3.6175
JeKo-1 GDSC1 2.5859 5.4915 0.1728 5.3627
SUP-B8 GDSC2 2.6031 5.6469 -1.0621 1.9741
MOLT-13 GDSC1 2.6074 4.605 0.5874 2.4733
LAMA-84 GDSC1 2.6174 5.9276 -0.0115 6.6066
KMS-11 GDSC2 2.6226 4.7387 -0.6986 0.6146
SU-DHL-8 GDSC1 2.6309 4.9765 0.4358 3.4309
SU-DHL-10 GDSC1 2.6416 3.5776 1.0172 0.2351
JSC-1 GDSC1 2.6611 4.7268 0.5634 2.5336
MHH-PREB-1 GDSC1 2.6771 7.8585 -0.8974 12.6098
OCI-AML-5 GDSC1 2.6818 4.2121 0.7914 1.1553
HAL-01 GDSC1 2.6891 5.2963 0.3254 4.0666
HH [Human lymphoma] GDSC1 2.6978 7.6198 -0.7672 11.6871
Raji GDSC1 2.6991 4.0913 0.8477 0.8533
JVM-3 GDSC1 2.6996 4.8729 0.5205 2.7421
GA-10 GDSC1 2.7008 4.4011 0.723 1.5049
CTB-1 GDSC1 2.7146 8.5519 -1.2084 14.4885
Karpas-422 GDSC1 2.7222 5.337 0.3265 3.9919
BC-1 GDSC1 2.723 11.8942 -2.8468 22.923
Reh GDSC1 2.7261 4.4072 0.7329 1.4158
Jurkat GDSC1 2.7282 7.5117 -0.6938 11.1095
ATN-1 GDSC1 2.7394 6.0288 0.0188 6.1003
BC-1 GDSC2 2.7418 4.4444 -0.5483 0.2228
Loucy GDSC1 2.7435 4.8288 0.5635 2.3937
U266B1 GDSC1 2.7523 6.3928 -0.1435 7.2181
SU-DHL-16 GDSC1 2.7554 4.0278 0.8967 0.5847
ME1 GDSC1 2.7594 4.3085 0.7888 1.0786
NALM-6 GDSC2 2.7595 4.3713 -0.5169 0.1691
P32/ISH GDSC1 2.7662 4.066 0.8867 0.6171
CCRF-CEM GDSC1 2.7722 4.8645 0.5633 2.3475
Hs 445 GDSC1 2.7938 5.0617 0.4894 2.7767
Ramos.2G6.4C10 GDSC1 2.8001 4.4758 0.7403 1.2822
MOLM-13 GDSC1 2.8084 5.2671 0.4071 3.2841
SUP-B8 GDSC1 2.8111 5.5015 0.304 3.9659
DG-75 GDSC1 2.8189 8.3683 -1.0451 13.1668
ARH-77 GDSC1 2.8198 4.4867 0.7452 1.2328
EM-2 GDSC1 2.8273 5.0303 0.521 2.5202
KMOE-2 GDSC1 2.8304 5.2215 0.4394 3.0336
CMK GDSC1 2.8358 4.1279 0.8923 0.5399
ROS-50 GDSC1 2.8397 7.4318 -0.5794 10.0341
PL-21 GDSC2 2.8513 4.785 -0.6271 0.3393
P12-Ichikawa GDSC1 2.8537 4.2518 0.8529 0.6858
JJN-3 GDSC1 2.8604 5.7075 0.2398 4.3019
BE-13 GDSC1 2.8628 4.9489 0.5745 2.1365
L-363 GDSC1 2.8928 4.3439 0.8342 0.7317
OCI-AML-3 GDSC1 2.8957 4.2817 0.8592 0.6252
Karpas-231 GDSC1 2.9028 4.244 0.8763 0.5521
A4/Fukuda GDSC1 2.9043 5.4749 0.3688 3.359
THP-1 GDSC1 2.9264 4.697 0.7101 1.2892
P31/FUJ GDSC2 2.9323 13.3623 -4.4233 17.4944
NALM-6 GDSC1 2.9479 8.6949 -1.1132 13.2404
CML-T1 GDSC1 2.9736 8.8325 -1.1619 13.4727
CTV-1 GDSC1 2.9813 4.9898 0.6168 1.7233
OCI-Ly7 GDSC1 2.9882 4.5331 0.8025 0.7854
MLMA GDSC1 2.9917 11.224 -2.3159 19.762
RPMI-6666 GDSC1 3.0085 5.3746 0.4686 2.5512
OCI-AML-2 GDSC1 3.0093 4.3912 0.8649 0.5198
697 GDSC1 3.0212 5.044 0.6139 1.6867
Jiyoye GDSC1 3.0296 5.4123 0.4634 2.5492
EJM GDSC1 3.0324 5.0177 0.63 1.5842
JURL-MK1 GDSC1 3.0434 5.7829 0.3101 3.4887
ST486 GDSC1 3.0461 4.9497 0.6642 1.3871
RCH-ACV GDSC1 3.0469 9.2518 -1.3137 14.1984
Granta-519 GDSC1 3.0943 4.6317 0.8097 0.6683
P31/FUJ GDSC1 3.1122 4.5572 0.8448 0.5233
NKM-1 GDSC1 3.1257 5.7652 0.3624 3.0159
VAL GDSC1 3.159 4.9832 0.7022 1.0774
QIMR-WIL GDSC1 3.1599 5.5461 0.4736 2.292
NKM-1 GDSC2 3.1628 5.1915 -0.6549 0.2966
YT GDSC1 3.1685 4.8937 0.7412 0.8923
WSU-NHL GDSC1 3.1699 5.1801 0.629 1.4245
HL-60 GDSC1 3.1793 4.6479 0.8382 0.5034
JVM-2 GDSC1 3.1831 5.6848 0.4268 2.5329
RPMI-8226 GDSC1 3.194 5.1036 0.6705 1.1923
NU-DUL-1 GDSC1 3.1992 5.3778 0.5627 1.7379
Ku812 GDSC1 3.2043 5.2352 0.6228 1.4168
Karpas-1106P GDSC1 3.2168 4.958 0.7372 0.8675
KM-H2 GDSC1 3.2236 7.6357 -0.4259 8.0469
RS4;11 GDSC1 3.2281 5.123 0.6781 1.1217
MEG-01 GDSC1 3.2319 6.2431 0.2117 3.7848
ALL-PO GDSC1 3.2356 7.1434 -0.1908 6.4382
SU-DHL-6 GDSC1 3.2363 4.9648 0.7429 0.8268
HDLM-2 GDSC1 3.2618 6.2641 0.2189 3.6866
GR-ST GDSC1 3.2691 9.1103 -1.0934 12.2656
ALL-PO GDSC2 3.2713 5.4954 -0.7214 0.3933
CRO-AP2 GDSC1 3.2993 5.3782 0.6094 1.3788
U-698-M GDSC1 3.3061 5.2945 0.6455 1.1969
EHEB GDSC1 3.308 7.1266 -0.1398 5.9441
KCL-22 GDSC1 3.3155 6.2898 0.2367 3.4827
KMS-11 GDSC1 3.321 6.0077 0.3606 2.7183
KY821 GDSC1 3.3231 4.8448 0.8229 0.4684
LP-1 GDSC1 3.331 4.9816 0.7758 0.626
H9 GDSC1 3.3346 8.5688 -0.7928 10.2002
ML-2 GDSC1 3.3364 4.9257 0.7986 0.5415
DB GDSC1 3.3407 5.5904 0.5433 1.6677
BALL-1 GDSC1 3.385 5.1024 0.7527 0.6738
VL51 GDSC1 3.391 6.3116 0.2673 3.1705
HEL GDSC1 3.3995 4.6717 0.9127 0.1973
CA46 GDSC1 3.4257 5.977 0.4259 2.1937
OPM-2 GDSC1 3.4309 5.0771 0.7805 0.5448
EoL-1 GDSC1 3.4315 4.9712 0.8191 0.4213
ALL-SIL GDSC1 3.4501 5.2949 0.7073 0.8006
HC-1 GDSC1 3.4548 5.3565 0.686 0.8831
L-428 GDSC1 3.4994 4.9458 0.8537 0.2958
HEL GDSC2 3.5108 16.9476 -5.7562 20.9893
SU-DHL-4 GDSC1 3.5666 4.8964 0.895 0.1832
SK-MM-2 GDSC1 3.6028 5.5034 0.6919 0.7474
Karpas-45 GDSC1 3.6105 5.2716 0.7798 0.4471
DND-41 GDSC1 3.6613 5.6756 0.6514 0.8599
EB2 GDSC1 3.6872 5.487 0.7316 0.5551
MOLP-8 GDSC1 3.7 5.2419 0.8238 0.2912
CESS GDSC1 3.7009 5.2578 0.8186 0.3032
L-1236 GDSC1 3.7872 6.345 0.447 1.6513
SUP-HD1 GDSC1 3.8128 5.9989 0.5924 0.9775
Mono-Mac-6 GDSC1 3.8781 7.2058 0.1382 3.1947
GDM-1 GDSC1 3.8782 6.1295 0.5703 1.0149
LC4-1 GDSC1 3.9517 6.4907 0.4631 1.4108
PL-21 GDSC1 3.9911 6.8638 0.3335 1.9901
KOPN-8 GDSC1 4.0152 5.6107 0.8098 0.2197
L-540 GDSC1 4.0466 5.7672 0.7672 0.2971
PF-382 GDSC1 4.1927 5.7099 0.8379 0.134
⏷ Show the Full List of 315 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-51 GDSC1 -7.6213 -1.5955 -7.824 82.9192
ESO-51 GDSC2 -6.8946 -2.4986 -7.0182 65.8991
OACP4 C GDSC2 1.1627 4.9256 -1.5741 7.0244
KYSE-50 GDSC2 1.3954 7.956 -2.8835 13.9184
ESO-26 GDSC2 1.4001 5.6027 -1.7379 7.4868
FLO-1 GDSC2 2 6.1309 -1.6025 5.5615
HCE-4 GDSC2 2.1321 4.474 -0.8085 1.3569
SK-GT-4 GDSC2 2.412 4.369 -0.6466 0.5768
KYAE-1 GDSC2 2.4509 4.5266 -0.6894 0.6829
KYAE-1 GDSC1 2.8721 5.1307 0.5016 2.5678
SK-GT-4 GDSC1 3.1052 7.438 -0.4084 8.2064
KYSE-220 GDSC2 3.1756 5.0915 -0.6157 0.2263
OACM5.1 C GDSC2 3.2035 5.4694 -0.7376 0.4532
ESO-26 GDSC1 3.4143 5.2016 0.7276 0.7483
FLO-1 GDSC1 3.5092 6.283 0.3399 2.5644
HCE-4 GDSC1 3.6505 5.4671 0.7245 0.6004
OACM5.1 C GDSC1 3.7272 5.8128 0.6271 0.9057
TE-12 GDSC2 3.7466 6.253 -0.8119 0.4209
KYSE-50 GDSC1 3.8855 5.8139 0.6903 0.5757
OACP4 C GDSC1 4.0721 6.8604 0.3717 1.7164
KYSE-220 GDSC1 4.6415 6.5227 0.7197 0.2193
TE-12 GDSC1 5.2697 8.179 0.371 0.8168
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 1.7858 4.8991 -1.17 3.546
COLO 684 GDSC1 4.2267 6.3272 0.6367 0.559
Cancer Drug Sensitivity Data Curated from 59 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-5 GDSC2 0.796 4.3454 -1.5503 7.7091
SJNB-14 GDSC2 0.7994 2.6587 -0.7369 2.789
SJNB-10 GDSC2 0.906 3.0982 -0.8748 3.3919
NB(TU)1 GDSC2 0.9886 3.4429 -0.9838 3.8722
SK-N-FI GDSC2 1.1368 2.9057 -0.6506 1.7615
CHP-212 GDSC2 1.2138 4.2966 -1.2405 4.9419
GOTO GDSC2 1.2799 7.2195 -2.6066 12.7138
SK-N-MC-IXC GDSC2 1.3135 2.6542 -0.4574 0.673
Kelly GDSC2 1.4073 3.1619 -0.6193 1.2694
KP-N-YN GDSC2 1.4084 4.0771 -1.0188 3.324
NH-12 GDSC2 1.4509 3.9511 -0.9376 2.8133
SK-N-DZ GDSC2 1.5719 12.6516 -5.0683 22.9095
SK-N-AS GDSC2 1.5721 4.8288 -1.2641 4.4161
CHP-134 GDSC2 1.6341 4.1576 -0.9268 2.4884
SJNB-6 GDSC2 1.7195 3.8738 -0.761 1.5709
CHP-126 GDSC2 1.8235 3.5852 -0.596 0.7879
SK-N-BE(2)-M17 GDSC2 1.8436 3.6658 -0.6186 0.8557
SJNB-13 GDSC2 1.8946 3.7462 -0.6274 0.8487
NB1 GDSC2 1.9078 4.3439 -0.8635 1.8315
TGW GDSC2 1.9079 3.6124 -0.5702 0.6385
MHH-NB-11 GDSC2 1.9311 3.4858 -0.5131 0.4489
SK-N-SH GDSC2 1.9326 3.8073 -0.6346 0.8458
SJNB-7 GDSC1 1.9668 14.2719 -4.6239 31.0564
SK-N-DZ GDSC1 2.0062 3.9185 0.54 4.0838
NB69 GDSC2 2.0412 4.0117 -0.6665 0.8796
SJNB-7 GDSC2 2.2406 3.7937 -0.5046 0.2919
SJNB-5 GDSC2 2.2435 3.8812 -0.5348 0.3598
SiMa GDSC2 2.2747 4.3687 -0.7034 0.841
LA-N-6 GDSC2 2.2811 3.8987 -0.5267 0.326
KP-N-YS GDSC2 2.3098 4.4956 -0.7372 0.934
SJNB-17 GDSC2 2.3749 4.5232 -0.7199 0.8287
GI-ME-N GDSC2 2.4657 10.315 -3.2754 13.4827
IMR-5 GDSC1 2.5476 5.5928 0.1011 5.9668
SJNB-6 GDSC1 2.8376 4.2983 0.828 0.8093
SK-N-FI GDSC1 2.9228 4.4343 0.8124 0.8004
SK-N-AS GDSC1 2.9531 4.4954 0.8018 0.8194
KP-N-RT-BM-1 GDSC2 2.9952 4.9516 -0.6324 0.3039
SK-N-MC-IXC GDSC1 3.0434 4.2854 0.9168 0.3284
SJNB-10 GDSC1 3.139 5.271 0.5775 1.7339
Kelly GDSC1 3.1398 4.8568 0.743 0.9102
NB69 GDSC1 3.1462 5.0138 0.6845 1.1747
NB1 GDSC1 3.1847 4.6606 0.8357 0.5088
GI-ME-N GDSC1 3.2129 7.4786 -0.3595 7.6248
SJNB-12 GDSC1 3.2539 6.5684 0.0801 4.597
SJNB-17 GDSC1 3.2716 5.5082 0.5441 1.7474
NH-12 GDSC1 3.277 5.13 0.6968 0.9898
SJNB-5 GDSC1 3.309 5.5848 0.5306 1.7729
SJNB-14 GDSC1 3.3454 5.2842 0.6669 1.0606
NB(TU)1 GDSC1 3.3518 5.0358 0.764 0.6551
SiMa GDSC1 3.3991 5.6991 0.5268 1.6844
LA-N-6 GDSC1 3.4607 5.3032 0.7086 0.7875
TGW GDSC1 3.5176 5.1156 0.8003 0.4336
SJNB-12 GDSC2 3.5738 5.4829 -0.6093 0.1415
KP-N-YN GDSC1 3.6122 5.5563 0.676 0.8012
CHP-126 GDSC1 3.8239 5.43 0.8034 0.2934
SK-N-BE(2)-M17 GDSC1 3.8837 5.7371 0.7173 0.4941
GOTO GDSC1 3.9564 5.9344 0.6741 0.5873
SJNB-13 GDSC1 3.9691 5.4387 0.852 0.1582
SK-N-SH GDSC1 4.1028 5.8153 0.7708 0.271
⏷ Show the Full List of 59 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 1.8163 3.5761 -0.5956 0.7918
HuCC-T1 GDSC1 2.9683 4.4892 0.8108 0.7669
Cancer Drug Sensitivity Data Curated from 100 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC2 0.9971 3.0902 -0.8144 2.8764
HCC1187 GDSC2 1.1071 6.7365 -2.496 12.5225
DU4475 GDSC2 1.2619 7.4195 -2.7179 13.3612
MCF-7 GDSC2 1.2884 6.9059 -2.4469 11.8119
COLO 824 GDSC2 1.3205 4.1058 -1.0846 3.8428
MDA-MB-361 GDSC2 1.4059 4.6783 -1.297 4.9043
CAL-51 GDSC2 1.4472 8.0001 -2.8674 13.7105
HCC1419 GDSC2 1.4508 4.0956 -1.0024 3.1647
HDQ-P1 GDSC2 1.4689 11.7284 -4.6896 21.8027
HCC1806 GDSC2 1.562 6.9822 -2.2906 10.3114
CAL-120 GDSC2 1.596 9.1695 -3.3322 15.6985
CAL-148 GDSC2 1.6203 3.189 -0.5308 0.7047
HCC1937 GDSC2 1.6344 11.1874 -4.2968 19.8801
MRK-nu-1 GDSC2 1.6392 3.1806 -0.5194 0.6495
Evsa-T GDSC2 1.656 4.12 -0.8986 2.3147
BT-474 GDSC2 1.6869 3.9219 -0.7976 1.7795
HCC1428 GDSC2 1.7265 10.6286 -3.9531 18.2264
BT-483 GDSC2 1.7373 7.9074 -2.6162 11.7102
AU565 GDSC2 1.7868 5.8483 -1.6031 5.9474
YMB-1-E GDSC2 1.8078 4.3605 -0.9218 2.2312
MDA-MB-175-VII GDSC2 1.8109 3.5587 -0.5912 0.7799
HCC1500 GDSC2 1.8205 3.9778 -0.7545 1.4331
BT-20 GDSC1 1.822 3.8068 0.4676 5.1271
JIMT-1 GDSC2 1.8306 7.7076 -2.4555 10.6375
HCC1599 GDSC2 1.8748 3.5947 -0.5774 0.6852
MDA-MB-453 GDSC2 1.9619 4.0084 -0.7006 1.0732
T-47D GDSC2 1.9923 4.565 -0.9138 1.9685
Hs 578T GDSC2 1.9969 3.7775 -0.5955 0.6641
HCC1954 GDSC2 2.0205 5.1731 -1.1601 3.1471
CAMA-1 GDSC2 2.0309 3.7947 -0.5878 0.6175
MFM-223 GDSC2 2.0526 3.6066 -0.5094 0.3794
HCC2218 GDSC2 2.0855 3.7794 -0.5597 0.5007
BT-20 GDSC2 2.1099 4.1072 -0.6736 0.8541
UACC-812 GDSC2 2.1772 3.8664 -0.5552 0.4415
HCC70 GDSC2 2.1948 3.8726 -0.5505 0.4208
MDA-MB-436 GDSC2 2.2309 4.3451 -0.7132 0.9064
EFM-192A GDSC2 2.2598 4.3911 -0.7184 0.9041
HCC1500 GDSC1 2.2977 4.5884 0.4126 4.3101
MDA-MB-468 GDSC2 2.3091 4.0367 -0.5656 0.4078
ZR-75-30 GDSC2 2.3492 4.7753 -0.8292 1.247
EFM-19 GDSC2 2.3566 4.3745 -0.6712 0.6823
HCC38 GDSC2 2.3568 4.5056 -0.7208 0.8441
OCUB-M GDSC2 2.3723 4.0498 -0.5461 0.3351
BT-549 GDSC2 2.4295 4.5192 -0.6955 0.7144
HCC1143 GDSC2 2.4429 5.6357 -1.1365 2.4865
MDA-MB-415 GDSC2 2.4927 4.1673 -0.5426 0.2851
BT-549 GDSC1 2.5042 6.928 -0.5674 10.8633
MDA-MB-157 GDSC2 2.5149 4.3295 -0.5919 0.3853
MDA-MB-231 GDSC2 2.5155 4.3918 -0.6141 0.439
HCC1569 GDSC2 2.5301 4.7666 -0.747 0.8168
HCC2157 GDSC1 2.5556 4.6661 0.5316 2.9336
HCC202 GDSC1 2.7176 11.1775 -2.4966 21.4022
Hs 578T GDSC1 2.7277 5.0363 0.4641 3.0582
DU4475 GDSC1 2.7468 4.1181 0.8583 0.7575
UACC-893 GDSC2 2.7668 4.7392 -0.6426 0.404
MDA-MB-157 GDSC1 2.7714 5.623 0.2257 4.5823
CAL-85-1 GDSC2 2.7853 5.1913 -0.8012 0.8311
HCC1395 GDSC2 2.8199 4.7171 -0.6148 0.3246
EFM-19 GDSC1 2.9086 6.0863 0.0962 5.1839
MDA-MB-330 GDSC2 2.9389 5.0443 -0.6862 0.4376
OCUB-M GDSC1 2.9507 5.3404 0.4528 2.7423
HCC1395 GDSC1 2.9627 5.3945 0.4358 2.8284
HCC2218 GDSC1 2.9668 6.0009 0.1695 4.5637
BT-474 GDSC1 3.0682 4.7236 0.7635 0.8845
HCC1419 GDSC1 3.0936 4.6368 0.8075 0.6778
MCF-7 GDSC1 3.149 5.2588 0.5873 1.6681
HCC1937 GDSC1 3.1686 5.9884 0.2886 3.4068
HCC1806 GDSC1 3.1803 4.8356 0.7684 0.767
MDA-MB-453 GDSC1 3.2655 4.9025 0.7786 0.6616
HCC1428 GDSC1 3.2707 5.0456 0.7266 0.8665
HDQ-P1 GDSC1 3.3534 5.1119 0.7362 0.7607
CAL-120 GDSC1 3.3715 5.1351 0.7349 0.7517
CAL-51 GDSC1 3.3953 4.9556 0.8108 0.4664
CAMA-1 GDSC1 3.3979 5.2535 0.7012 0.8669
EFM-192A GDSC1 3.416 5.1462 0.749 0.666
MRK-nu-1 GDSC1 3.4537 5.0792 0.7887 0.5044
MFM-223 GDSC1 3.4661 4.9979 0.8228 0.3933
JIMT-1 GDSC1 3.4714 5.2195 0.7442 0.6457
MDA-MB-415 GDSC1 3.5227 6.0374 0.4479 1.9499
HCC1187 GDSC1 3.5704 5.1382 0.8122 0.3738
HCC70 GDSC1 3.5715 5.8001 0.5651 1.3093
MDA-MB-330 GDSC1 3.6279 5.6562 0.6449 0.9118
UACC-893 GDSC1 3.6415 5.7437 0.6173 1.0142
HCC1954 GDSC1 3.6874 5.9045 0.5752 1.155
MDA-MB-468 GDSC1 3.7528 5.4507 0.7698 0.407
T-47D GDSC1 3.7763 6.5332 0.3665 2.0706
MDA-MB-361 GDSC1 3.7871 5.4895 0.769 0.394
MDA-MB-231 GDSC1 3.7957 6.0489 0.5662 1.0996
Evsa-T GDSC1 3.8162 5.2987 0.8459 0.2067
BT-483 GDSC1 3.8251 5.4386 0.8009 0.2988
CAL-85-1 GDSC1 3.9023 6.3859 0.4822 1.3709
MDA-MB-436 GDSC1 3.9368 6.0963 0.6069 0.83
HCC38 GDSC1 4.0041 5.8724 0.7146 0.444
HCC1143 GDSC1 4.0162 6.7182 0.4027 1.6266
HCC1599 GDSC1 4.0282 8.4286 -0.31 5.6446
MDA-MB-175-VII GDSC1 4.0704 5.739 0.7854 0.2511
ZR-75-30 GDSC1 4.1498 5.9637 0.7364 0.3303
COLO 824 GDSC1 4.2349 6.4496 0.5957 0.6812
HCC1569 GDSC1 4.2843 6.9562 0.427 1.2731
AU565 GDSC1 4.5978 6.5427 0.6975 0.27
⏷ Show the Full List of 100 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 108 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MOG-G-UVW GDSC1 0.2642 14.232 -6.0345 38.9745
U-118MG GDSC2 0.6842 4.119 -1.5208 7.7957
DK-MG GDSC1 0.7078 24.6413 -10.8534 42.3744
D283 Med GDSC2 0.8565 2.7889 -0.7617 2.827
MOG-G-UVW GDSC2 0.9324 6.0163 -2.2709 11.6757
D-336MG GDSC2 0.9551 5.7207 -2.1087 10.6765
SF539 GDSC2 1.1009 5.185 -1.7422 8.163
AM-38 GDSC2 1.1842 4.325 -1.2731 5.1918
SK-MG-1 GDSC2 1.2155 3.8131 -1.0139 3.6265
KINGS-1 GDSC2 1.2424 10.0946 -4.053 19.8394
42-MG-BA GDSC2 1.3108 4.0909 -1.0837 3.8548
NMC-G1 GDSC2 1.3308 2.7701 -0.4957 0.81
8-MG-BA GDSC2 1.3329 5.3778 -1.6755 7.2621
PFSK-1 GDSC2 1.3839 8.2902 -3.0559 14.8361
GaMG GDSC2 1.4684 4.7745 -1.3027 4.8211
YH-13 GDSC2 1.5345 3.5535 -0.7196 1.5906
Becker GDSC1 1.6006 13.8592 -4.716 32.3666
DK-MG GDSC2 1.6069 11.512 -4.4778 20.6627
LN-18 GDSC2 1.6522 10.7888 -4.087 18.9739
D-263MG GDSC2 1.7048 3.1712 -0.488 0.5013
SF295 GDSC2 1.7245 3.1776 -0.4824 0.4721
T98G GDSC2 1.7543 3.6654 -0.6589 1.0904
GI-1 GDSC2 1.7606 6.5999 -1.9733 8.099
U-251MG GDSC2 1.7761 6.9914 -2.1493 9.0592
H4 GDSC2 1.8143 7.231 -2.2381 9.4753
Hs 683 GDSC2 1.8627 3.4972 -0.5454 0.5867
SF295 GDSC1 1.8867 13.283 -4.1947 30.1291
SF126 GDSC2 1.8871 3.4058 -0.5013 0.4382
DBTRG-05MG GDSC2 1.9158 5.359 -1.3015 4.051
ONS-76 GDSC2 1.9757 3.6957 -0.5733 0.6055
GB-1 GDSC2 1.9936 11.4213 -4.1464 18.4202
Daoy GDSC2 1.9954 14.7274 -5.7741 24.2027
YKG-1 GDSC2 2.0441 3.6537 -0.5299 0.438
CAS-1 GDSC2 2.0705 3.9517 -0.6308 0.7331
KNS-42 GDSC2 2.1077 3.487 -0.4459 0.2156
D-542MG GDSC2 2.116 3.9181 -0.599 0.6013
D-502MG GDSC2 2.118 4.2953 -0.7436 1.1086
LN-405 GDSC2 2.1372 3.5611 -0.4611 0.236
H4 GDSC1 2.2155 10.8143 -2.7017 23.8431
D-392MG GDSC2 2.2294 4.8556 -0.9176 1.7265
A-172 GDSC2 2.2343 9.7675 -3.1704 13.4658
KS-1 [Human Krukenberg tumour] GDSC2 2.2568 5.009 -0.9675 1.919
D-566MG GDSC2 2.2743 3.8621 -0.5163 0.3052
SF268 GDSC2 2.276 9.5927 -3.0577 12.8214
SW1088 GDSC2 2.3111 4.2291 -0.6355 0.5995
U-87MG ATCC GDSC1 2.3121 4.748 0.347 4.7509
D-566MG GDSC1 2.368 8.3682 -1.372 16.524
SW1088 GDSC1 2.3688 11.2167 -2.7824 23.7109
Onda 10 GDSC2 2.3781 3.9997 -0.5261 0.2895
SF126 GDSC1 2.3805 4.446 0.5291 3.2996
D-247MG GDSC2 2.3839 4.3855 -0.6641 0.6444
M059J GDSC2 2.4124 4.2642 -0.6079 0.4699
LN-229 GDSC2 2.4253 11.953 -4.0957 17.2435
U-87MG ATCC GDSC2 2.4277 11.7281 -3.9847 16.7702
NMC-G1 GDSC1 2.464 4.8722 0.3842 4.136
MOG-G-CCM GDSC2 2.4655 4.4937 -0.6712 0.6197
D-502MG GDSC1 2.4994 5.0233 0.3362 4.3971
KNS-81-FD GDSC2 2.548 4.7265 -0.7245 0.7339
KS-1 [Human Krukenberg tumour] GDSC1 2.624 5.9646 -0.0247 6.6847
SW1783 GDSC1 2.6257 5.7747 0.0656 6.0346
D-263MG GDSC1 2.6295 6.1744 -0.1203 7.3559
Onda 11 GDSC2 2.7021 4.7436 -0.6691 0.4955
Becker GDSC2 2.7407 11.6355 -3.7225 14.9676
D-423MG GDSC2 2.7522 5.027 -0.7533 0.7035
KALS-1 GDSC1 2.8312 5.3124 0.3998 3.2901
D-542MG GDSC1 2.8488 4.6532 0.6911 1.4862
LN-229 GDSC1 2.8512 4.7442 0.6547 1.6857
SW1783 GDSC2 2.8799 5.2786 -0.7951 0.7566
LN-18 GDSC1 2.897 3.8555 1.0137 0.1454
GI-1 GDSC1 2.8973 8.5981 -1.1016 13.3066
T98G GDSC1 2.9636 6.2962 0.0333 5.4986
D-247MG GDSC1 2.9854 5.9184 0.2173 4.2059
SNB-75 GDSC2 3.0556 5.1055 -0.6641 0.3474
Daoy GDSC1 3.0696 6.9273 -0.1927 6.817
CAS-1 GDSC1 3.0922 5.0449 0.6473 1.4206
LN-405 GDSC1 3.1104 12.4551 -2.8335 21.7656
U-118MG GDSC1 3.1144 11.7454 -2.4819 20.1989
KALS-1 GDSC2 3.1362 5.3996 -0.7383 0.4809
42-MG-BA GDSC1 3.14 4.6504 0.8215 0.5895
D283 Med GDSC1 3.1653 4.5498 0.8685 0.4115
ONS-76 GDSC1 3.245 4.844 0.7921 0.6255
AM-38 GDSC1 3.2584 5.6586 0.4757 2.1409
Hs 683 GDSC1 3.2679 4.6317 0.8783 0.3303
8-MG-BA GDSC1 3.3169 5.1076 0.7225 0.8449
GB-1 GDSC1 3.3507 4.7255 0.8761 0.2998
D-336MG GDSC1 3.3781 8.3908 -0.6811 9.3728
YKG-1 GDSC1 3.5231 5.2835 0.7413 0.6223
DBTRG-05MG GDSC1 3.5238 5.6271 0.6116 1.1428
KNS-42 GDSC1 3.5549 5.4929 0.6762 0.8435
KINGS-1 GDSC1 3.6251 9.2107 -0.908 10.2385
D-245MG GDSC2 3.6628 6.3084 -0.863 0.5633
KNS-81-FD GDSC1 3.6955 12.6036 -2.4841 18.6552
YH-13 GDSC1 3.7136 14.709 -3.4981 22.792
D-392MG GDSC1 3.7186 13.4938 -2.9007 20.4314
Onda 10 GDSC1 3.7501 5.6557 0.6948 0.6399
SF539 GDSC1 3.7735 6.086 0.5424 1.2216
A-172 GDSC1 3.7946 5.4 0.8032 0.3044
SK-MG-1 GDSC1 3.8124 5.5832 0.7452 0.4481
GaMG GDSC1 3.8252 5.409 0.8112 0.2754
LNZTA3WT4 GDSC1 3.904 5.8262 0.6929 0.5571
D-423MG GDSC1 3.9224 6.1879 0.5667 0.9949
U-251MG GDSC1 3.9425 5.6735 0.7618 0.3475
SF268 GDSC1 3.943 5.6049 0.7859 0.291
MOG-G-CCM GDSC1 4.0143 6.3776 0.5333 1.0568
M059J GDSC1 4.0538 5.8853 0.7286 0.3858
SNB-75 GDSC1 4.3554 6.4294 0.6489 0.465
PFSK-1 GDSC1 4.7228 6.6565 0.7027 0.2284
Onda 11 GDSC1 4.7322 6.6159 0.7197 0.1988
⏷ Show the Full List of 108 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC2 0.6955 4.108 -1.5071 7.6842
ETK-1 GDSC2 0.7771 3.2467 -1.0303 4.5792
TGBC1TKB GDSC2 1.5167 3.589 -0.7437 1.7276
ETK-1 GDSC1 2.9367 5.5892 0.3363 3.5119
TGBC1TKB GDSC1 2.9862 4.7632 0.7113 1.215
TGBC24TKB GDSC1 4.1524 6.3757 0.5902 0.7483
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-296 GDSC2 1.3026 7.5653 -2.7596 13.4868
MFE-319 GDSC2 1.582 8.561 -3.0444 14.3043
ESS-1 GDSC2 1.7344 3.8315 -0.7361 1.4421
KLE GDSC2 1.7403 10.9144 -4.0835 18.7488
AN3-CA GDSC2 1.8149 3.7324 -0.6578 1.0313
RL95-2 GDSC2 1.8661 9.8271 -3.4585 15.669
MFE-280 GDSC2 1.9659 4.6708 -0.972 2.2775
EN GDSC2 2.0085 3.5176 -0.4943 0.3606
KLE GDSC1 3.0222 5.9754 0.2128 4.1646
MFE-280 GDSC1 3.1285 7.1673 -0.2675 7.1941
RL95-2 GDSC1 3.3287 5.0196 0.7607 0.684
MFE-319 GDSC1 3.3297 5.0397 0.7535 0.7106
MFE-296 GDSC1 3.333 5.5441 0.5584 1.5983
EN GDSC1 3.7113 4.8766 0.9514 0.0728
AN3-CA GDSC1 3.9242 7.5378 0.0211 3.8098
ESS-1 GDSC1 3.9827 5.3683 0.8802 0.1151
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 65 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-909 GDSC2 0.6179 4.7423 -1.878 10.1437
RCC10RGB GDSC2 1.0181 2.606 -0.5842 1.5859
A-498 GDSC2 1.4369 14.8211 -6.2497 26.8374
CAL-54 GDSC2 1.6465 3.5159 -0.6491 1.1517
VMRC-RCZ GDSC2 1.666 8.6217 -3.0136 13.9519
LB996-RCC GDSC2 1.7715 4.5582 -1.027 2.8122
A-704 GDSC2 1.7904 8.7614 -2.9931 13.5623
786-O GDSC2 1.8843 8.2375 -2.6738 11.6938
KMRC-20 GDSC2 1.8847 4.671 -1.0149 2.5943
SW13 GDSC2 1.9135 3.7761 -0.6308 0.8465
OS-RC-2 GDSC2 1.9893 4.4173 -0.8537 1.6958
SW156 GDSC1 2.0482 4.8837 0.104 7.2538
KMRC-1 GDSC2 2.0824 3.4989 -0.4595 0.2509
LB2241-RCC GDSC2 2.1105 4.1106 -0.6747 0.8574
KTCTL-13 GDSC2 2.1662 4.0918 -0.6437 0.7129
KTCTL-195 GDSC2 2.1843 3.8044 -0.5299 0.3729
VMRC-RCW GDSC2 2.3352 3.9069 -0.5094 0.2692
KTCTL-26A GDSC2 2.3362 4.3649 -0.676 0.7099
769-P GDSC2 2.3406 4.1325 -0.5881 0.4513
KTCTL-1M GDSC2 2.358 4.4145 -0.6857 0.7272
BB65-RCC GDSC2 2.3691 4.2643 -0.6251 0.5381
BFTC-909 GDSC1 2.3883 4.8028 0.3696 4.4099
TK-10 GDSC2 2.443 4.6635 -0.7446 0.866
NCC010 GDSC1 2.4533 8.6811 -1.4626 16.8018
RCC10RGB GDSC1 2.5188 4.4171 0.6213 2.4113
HA7-RCC GDSC2 2.5303 4.4877 -0.6432 0.5075
UO-31 GDSC2 2.5388 4.4418 -0.6231 0.4515
UO-31 GDSC1 2.5687 7.1789 -0.6438 11.2101
KTCTL-26A GDSC1 2.6015 9.6348 -1.8223 18.3856
SW156 GDSC2 2.6644 4.7997 -0.7044 0.6092
Caki-1 GDSC2 2.7319 4.7979 -0.6771 0.5027
A-704 GDSC1 2.826 4.9256 0.5654 2.2488
SN12C GDSC2 2.8911 4.715 -0.588 0.252
KTCTL-140 GDSC2 2.9356 4.977 -0.6635 0.3875
NCC021 GDSC2 2.9497 4.775 -0.5877 0.2359
RXF 393L GDSC2 2.9689 5.4254 -0.8135 0.7617
SN12C GDSC1 2.9936 6.4973 -0.0409 5.9432
A-498 GDSC1 3.0023 4.4481 0.8407 0.6162
769-P GDSC1 3.0617 5.4659 0.4572 2.5365
Caki-1 GDSC1 3.0825 5.6528 0.3879 2.9284
KTCTL-140 GDSC1 3.0919 6.3621 0.0794 4.9185
ACHN GDSC2 3.1616 4.8234 -0.53 0.1152
ACHN GDSC1 3.1967 5.8906 0.346 3.0013
KTCTL-1M GDSC1 3.2899 5.7119 0.4691 2.1352
KMRC-20 GDSC1 3.2954 10.0315 -1.5181 14.7267
KMRC-1 GDSC1 3.3423 4.8663 0.8225 0.4587
KTCTL-21 GDSC1 3.4139 6.5589 0.1728 3.7158
LB1047-RCC GDSC2 3.4733 5.6754 -0.7102 0.3095
KTCTL-195 GDSC1 3.5379 5.3391 0.7267 0.6644
LB2241-RCC GDSC1 3.5491 5.4924 0.6739 0.8569
SW13 GDSC1 3.6057 5.3826 0.7377 0.583
NCC010 GDSC2 3.6057 5.8047 -0.7072 0.27
BB65-RCC GDSC1 3.6607 5.6304 0.6682 0.7958
KTCTL-21 GDSC2 3.716 6.2863 -0.835 0.4798
KTCTL-13 GDSC1 3.77 6.0286 0.563 1.1353
786-O GDSC1 3.7767 5.6818 0.6958 0.6206
CAL-54 GDSC1 3.8708 5.7083 0.7227 0.4846
LB996-RCC GDSC1 3.9064 5.8579 0.6824 0.5889
RXF 393L GDSC1 3.9528 6.5152 0.4541 1.4508
OS-RC-2 GDSC1 4.0122 5.5632 0.8249 0.1931
VMRC-RCZ GDSC1 4.11 5.4692 0.8898 0.0848
HA7-RCC GDSC1 4.1362 6.2455 0.6313 0.6232
NCC021 GDSC1 4.2314 6.1794 0.6909 0.4085
LB1047-RCC GDSC1 4.2518 6.8079 0.4696 1.1259
TK-10 GDSC1 4.6524 6.8218 0.6208 0.4158
⏷ Show the Full List of 65 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 92 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO205 GDSC2 0.9252 5.127 -1.8393 9.1514
HCT 116 GDSC2 0.9624 4.3725 -1.4455 6.69
LS411N GDSC2 1.1171 4.1697 -1.2435 5.1515
SW948 GDSC2 1.2322 19.8512 -8.9183 32.8761
KM12 GDSC2 1.3242 6.1596 -2.0582 9.5178
SNU-C1 GDSC2 1.3254 3.5336 -0.8227 2.3901
NCI-H716 GDSC2 1.4268 6.8033 -2.2984 10.658
SNU-175 GDSC2 1.4277 5.4957 -1.6685 7.0233
COLO 320HSR GDSC2 1.5088 5.1755 -1.4644 5.676
RCM-1 [Human ESC] GDSC2 1.6337 3.1081 -0.4939 0.5657
HT-29 GDSC2 1.6421 2.9525 -0.4321 0.3696
RKO GDSC2 1.6577 3.3087 -0.5611 0.7877
GP5d GDSC2 1.6712 3.6992 -0.7123 1.4028
MDST8 GDSC2 1.7229 3.0232 -0.4261 0.3147
COLO 678 GDSC2 1.7266 5.7033 -1.5733 5.8897
HCT 15 GDSC2 1.7563 4.3625 -0.9499 2.439
CL-11 GDSC2 1.7598 4.3573 -0.9458 2.4138
SNU-283 GDSC2 1.763 3.4057 -0.5528 0.6782
LS180 GDSC2 1.769 3.3918 -0.5448 0.6466
CW-2 GDSC2 1.7804 5.4895 -1.4411 5.0462
HT115 GDSC2 1.7996 3.2686 -0.4857 0.4399
SNU-81 GDSC2 1.8059 3.3381 -0.5091 0.5065
SW1116 GDSC2 1.8303 3.6758 -0.6284 0.9036
HT-55 GDSC2 1.8987 3.1946 -0.4205 0.2321
SNU-407 GDSC2 1.9255 6.5464 -1.8414 7.0315
NCI-H508 GDSC2 1.9933 3.333 -0.4341 0.2283
LS1034 GDSC2 2.0314 4.0729 -0.6948 0.9926
SNU-61 GDSC2 2.0416 4.5494 -0.8828 1.7702
SNU-C5 GDSC2 2.0466 4.2814 -0.7708 1.2807
HCC2998 GDSC2 2.1141 9.3862 -3.0694 13.227
SW1463 GDSC2 2.1742 3.9262 -0.5784 0.5071
DiFi GDSC2 2.1909 6.1725 -1.5081 4.7275
SK-CO-1 GDSC2 2.1973 3.8882 -0.5552 0.432
T84 GDSC2 2.205 4.1893 -0.6644 0.7561
LS123 GDSC2 2.2359 4.2554 -0.6766 0.7762
SW48 GDSC2 2.2589 3.8425 -0.5151 0.3083
NCI-H508 GDSC1 2.2727 5.5362 -0.0551 7.8172
C2BBe1 GDSC2 2.3245 4.7937 -0.8478 1.342
LoVo GDSC2 2.3268 4.3631 -0.6793 0.7262
SW626 GDSC2 2.3496 4.6912 -0.7959 1.1186
CCK-81 GDSC2 2.3543 4.0801 -0.5638 0.3839
SW620 GDSC2 2.3567 4.1131 -0.5747 0.4099
SW837 GDSC2 2.4296 4.5265 -0.6982 0.7229
HCT 116 GDSC1 2.5916 4.1859 0.7585 1.4535
COLO205 GDSC1 2.5917 4.3575 0.6861 1.8811
NCI-H747 GDSC2 2.6188 5.3972 -0.9537 1.5057
NCI-H747 GDSC1 2.8005 5.9221 0.1061 5.3494
SNU-C1 GDSC1 2.805 4.8744 0.5763 2.2154
SW1417 GDSC1 2.8074 5.0731 0.4918 2.7376
CaR-1 GDSC2 2.8286 4.7054 -0.6075 0.307
SW1116 GDSC1 2.8415 4.8898 0.5887 2.0843
SW1417 GDSC2 2.8845 4.5369 -0.5293 0.1612
HT-29 GDSC1 2.8859 4.1761 0.8948 0.4946
SNU-C5 GDSC1 2.9453 5.2967 0.4688 2.6514
SNU-61 GDSC1 2.9606 6.0894 0.1258 4.8723
LS411N GDSC1 2.9644 4.3978 0.844 0.6324
LS1034 GDSC1 3.0031 4.8142 0.6986 1.2599
SNU-C2B GDSC2 3.0051 5.8081 -0.9434 1.1594
NCI-H716 GDSC1 3.0119 6.0969 0.1524 4.5883
HT115 GDSC1 3.0168 4.3676 0.8766 0.473
KM12 GDSC1 3.0238 4.4949 0.832 0.6342
SNU-81 GDSC1 3.1128 5.0046 0.673 1.2667
CW-2 GDSC1 3.1195 5.2748 0.5665 1.8191
SW1463 GDSC1 3.1226 5.0642 0.6536 1.3531
LoVo GDSC1 3.1646 5.2105 0.6143 1.5064
SW620 GDSC1 3.1724 5.1043 0.6605 1.2638
MDST8 GDSC1 3.1877 4.5025 0.8941 0.3239
SW948 GDSC1 3.2354 4.8982 0.7678 0.7261
HT-55 GDSC1 3.2419 4.6526 0.861 0.3937
LS513 GDSC1 3.4392 5.1913 0.7417 0.677
SK-CO-1 GDSC1 3.4791 5.1413 0.776 0.5309
RKO GDSC1 3.504 5.4218 0.6818 0.8606
SNU-1040 GDSC1 3.5172 5.1573 0.785 0.4803
SW626 GDSC1 3.5212 5.9369 0.4879 1.7425
LS180 GDSC1 3.5393 5.167 0.7901 0.453
HCC2998 GDSC1 3.5792 5.4874 0.6883 0.7783
RCM-1 [Human ESC] GDSC1 3.5915 5.1144 0.8285 0.3218
GP5d GDSC1 3.6083 5.3391 0.7546 0.5261
SW48 GDSC1 3.8015 5.8063 0.6599 0.7291
CCK-81 GDSC1 3.8695 5.7526 0.7062 0.5346
C2BBe1 GDSC1 3.8921 5.7555 0.7139 0.4999
COLO 320HSR GDSC1 3.9034 5.785 0.7076 0.5127
HCT 15 GDSC1 4.0026 5.5208 0.8359 0.1766
LS123 GDSC1 4.0087 5.5483 0.8287 0.1873
SNU-C2B GDSC1 4.1047 6.5366 0.5109 1.0757
CaR-1 GDSC1 4.1304 5.8984 0.752 0.3021
SW837 GDSC1 4.1641 6.1113 0.6899 0.4395
SNU-407 GDSC1 4.1913 5.8185 0.801 0.1902
COLO 678 GDSC1 4.3203 6.6221 0.5663 0.7273
CL-11 GDSC1 4.3818 6.2004 0.738 0.2534
T84 GDSC1 4.3909 6.3942 0.6743 0.3868
DiFi GDSC1 4.4583 6.4701 0.6725 0.3664
⏷ Show the Full List of 92 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 1.5649 3.2078 -0.563 0.8726
MO-T GDSC1 3.3396 5.3567 0.636 1.2083
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep-G2/C3A GDSC2 1.1174 5.0492 -1.6649 7.6653
JHH-7 GDSC2 1.3037 3.2485 -0.7096 1.8333
HuH-1 GDSC2 1.3604 9.6802 -3.7584 18.2598
SNU-423 GDSC2 1.3867 4.7437 -1.3398 5.1877
SNU-398 GDSC2 1.5238 4.9995 -1.3727 5.1203
Huh-7 GDSC2 1.5893 4.1291 -0.9388 2.6145
SK-HEP-1 GDSC2 1.6743 3.5504 -0.6499 1.1281
JHH-1 GDSC2 1.7833 3.1774 -0.4586 0.3719
Hep 3B2.1-7 GDSC2 1.8946 3.7882 -0.6439 0.9102
JHH-2 GDSC2 2.1538 4.07 -0.6406 0.7108
HLE GDSC2 2.1597 4.1491 -0.6683 0.8001
JHH-7 GDSC1 2.3437 4.4186 0.5196 3.4441
SNU-387 GDSC2 2.5451 4.6724 -0.7054 0.677
SNU-423 GDSC1 2.627 6.8252 -0.4327 9.5822
JHH-6 GDSC1 2.7205 3.4983 1.0732 0.0843
HLE GDSC1 2.756 4.7707 0.5951 2.178
JHH-1 GDSC1 2.9738 4.4321 0.8349 0.6615
HuH-1 GDSC1 3.1661 4.583 0.8567 0.449
Hep-G2/C3A GDSC1 3.2427 5.0112 0.7279 0.8849
SNU-449 GDSC2 3.2816 5.1109 -0.5851 0.1607
SNU-387 GDSC1 3.3391 5.2244 0.6873 0.976
SNU-398 GDSC1 3.3643 5.315 0.6632 1.0596
JHH-4 GDSC1 3.3939 5.2055 0.7177 0.8028
SNU-449 GDSC1 3.4021 8.005 -0.4861 8.0403
Huh-7 GDSC1 3.481 5.1495 0.7738 0.5373
SK-HEP-1 GDSC1 3.5102 4.6489 0.9589 0.0943
Hep 3B2.1-7 GDSC1 3.5861 5.3085 0.7571 0.5307
JHH-2 GDSC1 3.9136 9.3523 -0.794 8.882
JHH-6 GDSC2 4.1897 16.663 -5.1516 17.7359
JHH-4 GDSC2 5.0276 15.8486 -4.2293 12.9068
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 356 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EBC-1 GDSC1 -8.2901 -5.2194 -8.2929 95.2272
EBC-1 GDSC2 -7.8783 -5.7453 -7.8789 77.9883
NCI-H1993 GDSC2 -2.7248 7.1257 -6.0277 38.7407
NCI-H1975 GDSC1 -0.8608 1.2184 -1.0327 28.3821
NCI-H1993 GDSC1 -0.5666 44.3875 -21.8042 47.4303
NCI-H1155 GDSC2 0.56 11.0031 -5.0421 25.3894
NCI-H2369 GDSC2 0.699 4.5996 -1.7465 9.1405
RERF-LC-MS GDSC2 0.7008 10.724 -4.7898 24.1318
LCLC-103H GDSC2 0.7681 8.2028 -3.4802 18.506
NCI-H2461 GDSC1 0.9418 15.8711 -6.2718 37.3272
NCI-H345 GDSC2 0.9493 1.7677 -0.2724 0.2813
NCI-H526 GDSC2 0.9577 2.6173 -0.623 1.8794
NCI-H64 GDSC2 1.0011 2.3937 -0.5015 1.1917
RERF-LC-MS GDSC1 1.0097 19.3774 -7.9672 39.3398
NCI-H2009 GDSC2 1.0554 6.2889 -2.3141 11.6216
NCI-H2122 GDSC2 1.0834 2.9264 -0.6894 2.0436
NCI-H23 GDSC2 1.0884 3.8431 -1.1079 4.4076
NCI-H835 GDSC2 1.1217 3.6678 -1.0047 3.7429
NCI-H1048 GDSC2 1.1337 5.5485 -1.8956 8.9996
NCI-H1770 GDSC2 1.1405 2.9143 -0.6523 1.7652
NCI-H2029 GDSC2 1.1548 4.8034 -1.5208 6.7233
DMS 273 GDSC2 1.1629 6.5972 -2.3867 11.7735
EPLC-272H GDSC2 1.1751 5.9889 -2.0806 9.989
NCI-H1694 GDSC2 1.2092 6.3005 -2.2082 10.6467
SBC-5 GDSC2 1.2115 8.7466 -3.4092 17.0117
BEN GDSC2 1.2307 2.4727 -0.423 0.6093
NCI-H226 GDSC2 1.2325 2.716 -0.5203 1.0122
NCI-H2228 GDSC2 1.311 8.4429 -3.1849 15.6651
NCI-H720 GDSC2 1.3171 3.9025 -0.9935 3.3355
EMC-BAC-2 GDSC2 1.3196 4.7829 -1.4014 5.6775
NCI-H1623 GDSC2 1.339 6.5054 -2.2156 10.3886
COR-L88 GDSC2 1.3515 3.3177 -0.714 1.7919
NCI-H2227 GDSC1 1.3572 3.3239 0.3502 7.5353
NCI-H2141 GDSC2 1.3615 5.4448 -1.6884 7.2772
NCI-H2085 GDSC2 1.362 4.1565 -1.0827 3.7593
LOU-NH91 GDSC2 1.3902 6.4602 -2.1577 9.9416
COR-L23 GDSC2 1.4112 2.9067 -0.5133 0.8091
NCI-H1869 GDSC2 1.4178 3.5444 -0.7767 2.0195
NCI-H1963 GDSC2 1.4411 5.7105 -1.762 7.5412
NCI-H1915 GDSC2 1.4531 6.4773 -2.1222 9.5985
NCI-H460 GDSC2 1.4557 2.7697 -0.4402 0.5043
HOP-62 GDSC2 1.4598 3.5619 -0.7619 1.8888
NCI-H1563 GDSC2 1.4638 3.6931 -0.8166 2.1595
LCLC-97TM1 GDSC2 1.4781 4.0805 -0.9799 2.9993
NCI-H2444 GDSC2 1.4913 2.4754 -0.3184 0.1581
Lu-99A GDSC2 1.5111 4.8801 -1.3252 4.8716
COR-L311 GDSC2 1.518 4.6205 -1.2012 4.1567
NCI-H446 GDSC2 1.5209 11.7524 -4.6618 21.5725
COR-L321 GDSC2 1.5452 3.1833 -0.5623 0.8869
IA-LM GDSC2 1.5601 3.8017 -0.8121 2.0079
NCI-H661 GDSC2 1.5641 3.871 -0.8398 2.1415
NCI-H1435 GDSC2 1.5649 10.2768 -3.8997 18.3825
A-427 GDSC2 1.6385 10.665 -4.0362 18.7918
NCI-H1648 GDSC2 1.6485 4.8752 -1.2393 4.1467
NCI-H1734 GDSC2 1.6524 4.1508 -0.9139 2.3973
NCI-H82 GDSC2 1.6595 3.7827 -0.7529 1.6012
COR-L303 GDSC2 1.6871 3.4378 -0.5988 0.9087
NCI-H2591 GDSC2 1.7244 12.236 -4.747 21.4009
Lu-165 GDSC2 1.7315 3.001 -0.4147 0.2825
COR-L279 GDSC2 1.7494 3.8354 -0.7304 1.4009
NCI-H522 GDSC2 1.7564 4.0092 -0.7992 1.7056
HOP-92 GDSC2 1.7725 8.1262 -2.6975 12.0658
Lu-65 GDSC2 1.7744 3.7899 -0.6998 1.2425
NCI-H1944 GDSC2 1.7811 7.6147 -2.4447 10.685
NCI-H196 GDSC2 1.7872 3.5251 -0.5885 0.7882
HCC33 GDSC2 1.7984 3.562 -0.598 0.8145
NCI-H1650 GDSC2 1.803 4.6381 -1.0448 2.8595
NCI-H838 GDSC2 1.8148 3.4475 -0.5467 0.6218
NCI-H1573 GDSC2 1.8268 6.2486 -1.7647 6.787
NCI-H1693 GDSC2 1.8425 4.255 -0.859 1.8859
Ms-1 GDSC2 1.8546 3.7662 -0.6532 0.9788
Lu-135 GDSC2 1.872 3.6877 -0.6146 0.819
HCC15 GDSC2 1.8755 11.0236 -4.0376 18.237
NCI-H2405 GDSC2 1.886 4.4831 -0.9334 2.1894
NCI-H1437 GDSC2 1.8898 3.8556 -0.6727 1.0251
IST-SL2 GDSC2 1.8971 6.6475 -1.907 7.4545
NCI-H520 GDSC2 1.8972 4.3441 -0.8689 1.8687
NCI-H841 GDSC2 1.8998 3.7013 -0.6077 0.7733
NCI-H1836 GDSC2 1.9188 3.4142 -0.4918 0.3957
NCI-H2347 GDSC2 1.9193 5.0979 -1.183 3.4125
NCI-H596 GDSC2 1.9215 3.3683 -0.474 0.3478
NCI-H1666 GDSC2 1.9215 12.5855 -4.772 21.0316
LB647-SCLC GDSC2 1.924 3.7091 -0.6003 0.7298
NCI-H1781 GDSC2 1.9336 4.4565 -0.8978 1.9616
NCI-H1299 GDSC2 1.9359 12.5211 -4.7296 20.8416
NCI-H209 GDSC2 1.9384 3.9707 -0.6963 1.0765
NCI-H292 GDSC2 1.9403 3.8168 -0.6349 0.8409
NCI-H441 GDSC2 1.9429 4.3928 -0.8664 1.8048
NCI-H2595 GDSC2 1.9486 4.7184 -1.0014 2.4431
Calu-6 GDSC2 1.9499 4.1714 -0.7717 1.3767
NCI-H2291 GDSC2 1.9531 3.7679 -0.6105 0.7446
NCI-H1688 GDSC2 1.9713 4.0638 -0.7184 1.1357
HCC78 GDSC2 1.9725 3.7076 -0.5792 0.6263
NCI-H2196 GDSC2 1.9734 3.7777 -0.6055 0.7135
NCI-H2171 GDSC2 2.0046 3.4112 -0.4575 0.2745
NCI-H69 GDSC2 2.0065 3.5493 -0.5066 0.3934
NCI-H1092 GDSC2 2.0171 3.5693 -0.5097 0.3966
SBC-1 GDSC2 2.0184 3.6844 -0.5515 0.5133
NCI-H2066 GDSC2 2.0227 3.7649 -0.5799 0.5976
NCI-H1105 GDSC2 2.0253 3.7843 -0.5862 0.6158
SHP-77 GDSC2 2.049 3.5211 -0.4799 0.3086
NCI-H250 GDSC2 2.0673 3.9399 -0.6276 0.7247
NCI-H1563 GDSC1 2.0733 5.5549 -0.2057 9.5059
NCI-H2795 GDSC2 2.0776 4.5832 -0.8791 1.7149
NCI-H345 GDSC1 2.0862 3.4178 0.8216 1.8895
SBC-5 GDSC1 2.0944 10.9706 -2.8748 24.9527
NCI-H1694 GDSC1 2.1061 3.9951 0.5686 3.6287
NCI-H2135 GDSC2 2.1138 3.6506 -0.5016 0.3337
NCI-H2227 GDSC2 2.1157 3.8121 -0.5597 0.4847
RERF-LC-Sq1 GDSC2 2.1198 7.9404 -2.373 9.5874
RERF-LC-KJ GDSC2 2.129 4.1584 -0.6852 0.8813
NCI-H650 GDSC2 2.13 4.9289 -0.9973 2.1996
SBC-3 GDSC2 2.1334 3.9076 -0.5879 0.5574
NCI-H1838 GDSC2 2.1334 3.8294 -0.559 0.4736
DMS 53 GDSC2 2.1374 7.6988 -2.2472 8.8693
CAL-12T GDSC2 2.1512 3.9365 -0.5915 0.558
LCLC-103H GDSC1 2.1517 6.0256 -0.3793 10.548
NCI-H1781 GDSC1 2.1536 4.4162 0.4009 4.7437
NCI-H2170 GDSC2 2.1546 11.1394 -3.8921 16.9748
NCI-H146 GDSC2 2.165 4.2663 -0.7114 0.9492
HCC366 GDSC2 2.1659 4.1394 -0.662 0.7742
NCI-H2023 GDSC2 2.1757 10.6071 -3.6179 15.7082
NCI-H3255 GDSC2 2.1775 4.057 -0.6258 0.6481
LK-2 GDSC2 2.1807 3.9588 -0.5878 0.5309
HCC827 GDSC2 2.181 4.1357 -0.6542 0.7377
Calu-3 GDSC2 2.1832 4.4336 -0.769 1.1524
UMC-11 GDSC2 2.1888 15.6308 -6.0747 24.6579
IST-SL1 GDSC2 2.1906 4.4256 -0.7624 1.1208
NCI-H1568 GDSC2 2.1941 12.6438 -4.5997 19.7654
NCI-H2023 GDSC1 2.1952 14.311 -4.46 29.9645
NCI-H2342 GDSC2 2.1953 4.6092 -0.8336 1.4016
NCI-H1581 GDSC2 2.2 3.8607 -0.5442 0.4021
NCI-H510A GDSC2 2.2098 3.8403 -0.533 0.3698
BEN GDSC1 2.2209 4.8133 0.2567 5.6412
SK-MES-1 GDSC2 2.2215 10.0437 -3.3127 14.1815
DMS 79 GDSC2 2.2243 3.8538 -0.5323 0.3619
NCI-H1436 GDSC2 2.2326 3.7096 -0.478 0.2393
NCI-H1876 GDSC2 2.234 3.8466 -0.526 0.3429
NCI-H2030 GDSC2 2.2345 3.9842 -0.5757 0.469
LXF 289 GDSC2 2.2489 9.2528 -2.9129 12.1529
NCI-H290 GDSC2 2.2565 4.1065 -0.612 0.5602
NCI-H810 GDSC2 2.2728 3.8354 -0.5073 0.2862
NCI-H524 GDSC2 2.2835 18.3563 -7.3515 27.7054
PC-14 GDSC2 2.292 4.3827 -0.7014 0.8223
Lu-65 GDSC1 2.304 4.334 0.5343 3.4259
NCI-H460 GDSC1 2.3058 8.3498 -1.4095 16.9432
NCI-H513 GDSC2 2.3253 10.8036 -3.608 15.3344
NCI-H2373 GDSC2 2.3276 6.5022 -1.5773 4.8803
NCI-H2081 GDSC2 2.3349 4.1969 -0.6139 0.5243
NCI-H358 GDSC2 2.3498 4.3347 -0.6591 0.6487
NCI-H748 GDSC2 2.3505 4.4662 -0.7085 0.8067
Lu-134-A GDSC2 2.3786 4.4614 -0.6948 0.7438
LXF 289 GDSC1 2.3844 4.6511 0.4374 3.9348
NCI-H847 GDSC2 2.3878 3.9067 -0.49 0.2159
NCI-H727 GDSC2 2.3978 4.6554 -0.7608 0.9539
COR-L32 GDSC2 2.3979 4.4014 -0.6643 0.6369
NCI-H2818 GDSC2 2.4026 4.1415 -0.5674 0.3727
NCI-H1792 GDSC2 2.4068 4.2176 -0.5931 0.4342
NCI-H2722 GDSC1 2.4148 9.754 -2.0216 20.0089
SW1573 GDSC2 2.4148 9.3177 -2.8327 11.4027
HCC44 GDSC1 2.4275 4.9956 0.3044 4.7873
NCI-H322M GDSC2 2.4357 5.2904 -0.9966 1.8597
CPC-N GDSC2 2.4389 4.1302 -0.5495 0.3182
PC-14 GDSC1 2.4396 5.0639 0.2802 4.9334
LC-2/ad GDSC2 2.4591 4.4571 -0.6602 0.591
COR-L32 GDSC1 2.4857 5.8959 -0.083 7.4534
NCI-H2172 GDSC2 2.4985 3.8164 -0.4204 0.0927
NCI-H1793 GDSC2 2.5076 14.7037 -5.3811 21.8389
NCI-H2291 GDSC1 2.517 9.1639 -1.6531 17.7066
RERF-LC-KJ GDSC1 2.5225 4.6336 0.5273 3.0259
HCC78 GDSC1 2.5355 4.6013 0.5491 2.8549
HARA [Human squamous cell lung carcinoma] GDSC2 2.5472 4.3678 -0.5933 0.3758
ABC-1 GDSC2 2.5559 4.5087 -0.6408 0.4892
DMS 114 GDSC2 2.5612 4.3111 -0.5678 0.3143
LOU-NH91 GDSC1 2.5718 6.8595 -0.4871 10.1136
NCI-H211 GDSC2 2.5746 4.6305 -0.6779 0.5809
KNS-62 GDSC2 2.579 4.0974 -0.4872 0.1641
NCI-H82 GDSC1 2.5814 7.6646 -0.8709 12.7075
NCI-H1703 GDSC2 2.5933 4.4937 -0.6208 0.4224
SW1271 GDSC2 2.6038 4.3783 -0.5757 0.3162
A-549 GDSC2 2.6219 4.8783 -0.751 0.7724
NCI-H1755 GDSC2 2.6389 4.7628 -0.7011 0.6129
NCI-H1651 GDSC2 2.6408 4.254 -0.5189 0.1992
NCI-H2810 GDSC2 2.6422 5.0069 -0.7912 0.8894
NCI-H596 GDSC1 2.6438 4.6636 0.5816 2.4473
NCI-H1975 GDSC2 2.6442 15.6462 -5.7437 22.7005
NCI-H2804 GDSC2 2.6524 4.9241 -0.7557 0.7685
NCI-H1435 GDSC1 2.6678 5.0194 0.4378 3.3461
PaCa-3 GDSC2 2.6881 4.8234 -0.7037 0.5949
NCI-H522 GDSC1 2.696 4.802 0.5496 2.5617
NCI-H2135 GDSC1 2.7038 4.5094 0.6792 1.7528
LC-1/sq GDSC2 2.7121 12.3776 -4.1002 16.6485
VMRC-LCD GDSC2 2.7176 4.2657 -0.4958 0.1479
EMC-BAC-2 GDSC1 2.7293 9.9482 -1.8819 18.3253
NCI-H2803 GDSC2 2.7522 4.4901 -0.5603 0.2409
SK-LU-1 GDSC2 2.7562 4.4785 -0.5549 0.2303
NCI-H1304 GDSC1 2.7784 4.6955 0.6386 1.8821
NCI-H2444 GDSC1 2.7836 3.7283 1.0168 0.1765
COLO 668 GDSC2 2.7836 4.6389 -0.6008 0.3079
NCI-H23 GDSC1 2.7941 9.073 -1.4057 15.4552
DMS 79 GDSC1 2.8035 5.736 0.1932 4.7383
NCI-H1341 GDSC1 2.8324 17.1794 -5.3859 30.5807
NCI-H647 GDSC2 2.8349 4.5893 -0.5648 0.2268
ChaGo-K-1 GDSC2 2.8388 4.7947 -0.6352 0.3607
HOP-92 GDSC1 2.842 7.1631 -0.4496 9.137
NCI-H2087 GDSC2 2.8441 5.2522 -0.7998 0.7916
HARA [Human squamous cell lung carcinoma] GDSC1 2.8454 6.2369 -0.0117 6.0717
NCI-H1944 GDSC1 2.864 5.4281 0.3669 3.4451
LK-2 GDSC1 2.8653 12.0318 -2.8075 22.3457
NCI-H2731 GDSC2 2.869 4.7519 -0.6089 0.2971
IST-SL1 GDSC1 2.8728 5.0652 0.5301 2.3905
NCI-H1793 GDSC1 2.8757 5.6402 0.279 4.007
NCI-H446 GDSC1 2.8778 12.9601 -3.2569 24.1175
NCI-H524 GDSC1 2.8928 4.9857 0.5743 2.093
KNS-62 GDSC1 2.9009 4.9626 0.5882 1.999
NCI-H2869 GDSC2 2.9123 5.2968 -0.7887 0.7196
HCC44 GDSC2 2.9144 13.2584 -4.3855 17.383
SHP-77 GDSC1 2.9263 4.5059 0.786 0.9165
NCI-H3122 GDSC2 2.9352 4.866 -0.6246 0.3071
NCI-H2731 GDSC1 2.9651 5.5933 0.3503 3.3695
COR-L279 GDSC1 2.975 4.6274 0.76 0.9897
NCI-H1355 GDSC2 2.9775 4.9746 -0.647 0.3383
DMS 273 GDSC1 2.9848 4.7038 0.7343 1.1029
NCI-H847 GDSC1 2.9878 4.4324 0.8406 0.6277
Lu-165 GDSC1 2.9963 4.5504 0.7993 0.7922
COR-L23 GDSC1 3.0011 4.5847 0.7881 0.8368
IA-LM GDSC1 3.0026 4.679 0.752 0.9996
CPC-N GDSC1 3.0026 5.3664 0.469 2.5579
NCI-H740 GDSC2 3.0232 4.9761 -0.6308 0.2924
NCI-H2369 GDSC1 3.04 4.6931 0.7631 0.9126
NCI-H187 GDSC1 3.0571 4.2993 0.9171 0.3209
NCI-H2009 GDSC1 3.0591 5.3182 0.5185 2.176
NCI-H720 GDSC1 3.0598 4.9356 0.6762 1.3097
NCI-H841 GDSC1 3.0717 10.2137 -1.7635 16.7059
NCI-H1568 GDSC1 3.0753 10.0198 -1.6666 16.1618
EKVX GDSC2 3.0956 5.4039 -0.7554 0.5395
Lu-135 GDSC1 3.1137 5.1752 0.6046 1.6196
NCI-H2461 GDSC2 3.1203 16.4716 -5.8024 21.9016
COR-L105 GDSC2 3.1233 5.1749 -0.6635 0.3246
NCI-H1573 GDSC1 3.1251 4.9817 0.6876 1.1815
NCI-H1755 GDSC1 3.1255 5.3115 0.5543 1.8794
NCI-H2110 GDSC2 3.132 5.2192 -0.6759 0.3463
NCI-H2595 GDSC1 3.134 11.7166 -2.4535 20.0125
NCI-H292 GDSC1 3.155 5.6611 0.4224 2.6021
NCI-H1770 GDSC1 3.1671 5.0469 0.6808 1.1709
NCI-H226 GDSC1 3.2039 4.5622 0.8789 0.3596
NCI-H358 GDSC1 3.2146 5.3739 0.5716 1.6708
NCI-H526 GDSC1 3.2179 4.8416 0.7818 0.684
IST-SL2 GDSC1 3.2264 6.1726 0.2395 3.6174
NCI-H1869 GDSC1 3.228 6.1296 0.2592 3.4903
COR-L321 GDSC1 3.2332 4.73 0.8294 0.4999
NCI-H69 GDSC1 3.2416 5.6537 0.4694 2.1997
EMC-BAC-1 GDSC1 3.2594 6.0236 0.3218 3.0484
NCI-H1693 GDSC1 3.2632 12.0287 -2.5124 19.9291
Lu-139 GDSC1 3.2672 5.3596 0.602 1.4513
NCI-H322M GDSC1 3.2693 6.084 0.3011 3.1599
NCI-H1651 GDSC1 3.2803 6.1618 0.2734 3.3133
HCC366 GDSC1 3.2873 6.583 0.0925 4.4531
NCI-H810 GDSC1 3.3036 4.78 0.8388 0.4288
NCI-H1836 GDSC1 3.3158 5.3308 0.6355 1.2343
NCI-H2172 GDSC1 3.3292 4.8016 0.8409 0.4088
NCI-H2081 GDSC1 3.3362 6.0831 0.3364 2.8395
NCI-H2066 GDSC1 3.3459 6.1545 0.311 2.9771
NCI-H2110 GDSC1 3.3488 6.3688 0.2203 3.5289
DMS 114 GDSC1 3.3491 5.2109 0.6967 0.9265
UMC-11 GDSC1 3.3494 5.0234 0.7677 0.643
NCI-H2722 GDSC2 3.3519 15.9304 -5.3741 20.0757
SBC-1 GDSC1 3.3609 5.0524 0.7616 0.6576
NCI-H2373 GDSC1 3.3654 5.6737 0.5212 1.7538
RERF-LC-Sq1 GDSC1 3.3858 6.4131 0.2209 3.4636
LCLC-97TM1 GDSC1 3.4039 5.6254 0.5586 1.5166
CAL-12T GDSC1 3.4078 5.5178 0.6031 1.295
NCI-H1355 GDSC1 3.4129 6.2385 0.3099 2.8804
NCI-H3255 GDSC1 3.4168 5.1544 0.7463 0.6754
NCI-H290 GDSC1 3.4214 5.9955 0.4161 2.2543
COR-L95 GDSC1 3.429 5.0406 0.7931 0.5042
NCI-H650 GDSC1 3.4396 5.1125 0.7709 0.5721
NCI-H1092 GDSC1 3.4398 5.1636 0.7522 0.6381
NCI-H1581 GDSC1 3.4539 5.0813 0.788 0.5064
NCI-H1648 GDSC1 3.4563 5.6715 0.5642 1.432
Ms-1 GDSC1 3.4695 5.1395 0.7729 0.5471
NCI-H146 GDSC1 3.4714 5.4317 0.6643 0.9597
NCI-H1105 GDSC1 3.477 5.6202 0.5937 1.2694
Calu-3 GDSC1 3.5131 5.3205 0.7235 0.6928
NCI-H2141 GDSC1 3.5153 5.4478 0.6767 0.8723
SK-MES-1 GDSC1 3.5183 5.5379 0.6436 1.0075
NCI-H2803 GDSC1 3.529 5.3183 0.7308 0.6555
NCI-H1650 GDSC1 3.5365 5.6317 0.6154 1.1144
SW1573 GDSC1 3.5406 6.6668 0.1935 3.3808
NCI-H661 GDSC1 3.5477 5.8443 0.5371 1.467
NCI-H1688 GDSC1 3.5505 10.491 -1.5646 14.3275
Calu-6 GDSC1 3.5649 5.6201 0.632 1.0171
HOP-62 GDSC1 3.5733 5.4253 0.709 0.7047
NCI-H1436 GDSC1 3.5842 4.9984 0.8663 0.2359
NCI-H2122 GDSC1 3.5918 4.8947 0.9045 0.1595
NCI-H2591 GDSC1 3.6034 8.3563 -0.5247 7.8481
NCI-H196 GDSC1 3.6155 5.1064 0.8402 0.2839
NCI-H209 GDSC1 3.6179 6.7297 0.2068 3.1808
NCI-H1299 GDSC1 3.6216 5.9882 0.5135 1.5035
NCI-H1437 GDSC1 3.6462 5.8405 0.5821 1.1617
HCC827 GDSC1 3.6598 5.3663 0.7647 0.467
SBC-3 GDSC1 3.6613 5.3693 0.7642 0.4678
NCI-H1915 GDSC1 3.6679 5.3498 0.7737 0.4363
SW1271 GDSC1 3.6748 5.4671 0.734 0.5544
NCI-H211 GDSC1 3.6825 5.6582 0.6667 0.7857
NCI-H647 GDSC1 3.6829 5.9562 0.5533 1.2565
HCC15 GDSC1 3.6856 6.22 0.4504 1.7455
NCI-H1155 GDSC1 3.6888 5.2633 0.8122 0.3234
NCI-H513 GDSC1 3.6949 7.828 -0.231 5.7688
COR-L88 GDSC1 3.7173 5.4569 0.7542 0.469
NCI-H1048 GDSC1 3.7174 5.2884 0.8139 0.308
NCI-H2085 GDSC1 3.7211 6.2231 0.4654 1.632
NCI-H1792 GDSC1 3.7281 5.651 0.6878 0.6782
NCI-H2228 GDSC1 3.7372 7.3091 0.0208 4.1125
EMC-BAC-1 GDSC2 3.7394 6.2149 -0.8011 0.4018
LB647-SCLC GDSC1 3.7465 5.6368 0.7003 0.6235
EKVX GDSC1 3.7545 5.9003 0.6053 0.9714
NCI-H835 GDSC1 3.7811 6.6922 0.3039 2.3988
NCI-H2795 GDSC1 3.799 5.8236 0.6524 0.7576
EPLC-272H GDSC1 3.8334 6.2476 0.5058 1.3292
NCI-H2405 GDSC1 3.8387 6.3356 0.4739 1.4705
NCI-H2810 GDSC1 3.8585 6.036 0.5974 0.9225
NCI-H727 GDSC1 3.8617 5.7227 0.714 0.5151
NCI-H2170 GDSC1 3.8714 5.4457 0.8152 0.2515
NCI-H1341 GDSC2 3.8731 19.693 -6.835 23.3639
DMS 53 GDSC1 3.8834 5.7096 0.727 0.4659
COLO 668 GDSC1 3.9121 5.9844 0.6384 0.733
NCI-H1876 GDSC1 3.9324 5.9623 0.6546 0.6649
LC-2/ad GDSC1 3.9517 6.1883 0.5786 0.926
NCI-H1623 GDSC1 3.9521 6.229 0.5635 0.9845
VMRC-LCD GDSC1 3.9547 5.5846 0.7972 0.2628
A-427 GDSC1 3.9632 6.1948 0.5809 0.9087
ChaGo-K-1 GDSC1 3.9983 5.9288 0.6923 0.51
NCI-H2818 GDSC1 4.0004 5.7631 0.7517 0.3497
Lu-99A GDSC1 4.0077 6.1478 0.6164 0.7488
NCI-H2029 GDSC1 4.0241 5.6775 0.79 0.2558
NCI-H520 GDSC1 4.0472 5.8964 0.7222 0.4048
ABC-1 GDSC1 4.0637 6.1502 0.6376 0.6436
NCI-H838 GDSC1 4.0645 5.8781 0.735 0.3655
NCI-H2869 GDSC1 4.0662 6.2216 0.6125 0.7253
SK-LU-1 GDSC1 4.0878 6.094 0.6672 0.5389
NCI-H1703 GDSC1 4.138 6.0469 0.7029 0.4165
A-549 GDSC1 4.1382 6.0962 0.6855 0.4627
NCI-H1838 GDSC1 4.1516 6.0179 0.7181 0.3729
NCI-H3122 GDSC1 4.1543 6.0122 0.7211 0.3645
NCI-H2347 GDSC1 4.1859 6.2222 0.6587 0.5152
NCI-H2087 GDSC1 4.3722 6.507 0.6277 0.5147
PaCa-3 GDSC1 4.3892 6.5835 0.6068 0.5655
NCI-H2804 GDSC1 4.4576 6.6981 0.5918 0.5753
NCI-H2030 GDSC1 4.5073 6.6255 0.6362 0.4345
Lu-134-A GDSC1 4.5296 6.8702 0.5577 0.6395
NCI-H1666 GDSC1 4.6625 6.6189 0.6944 0.2582
NCI-H2342 GDSC1 4.6805 6.84 0.6247 0.3964
NCI-H441 GDSC1 4.6983 15.9708 -3.4154 20.1318
LC-1/sq GDSC1 4.8055 7.0218 0.6069 0.3925
COR-L105 GDSC1 4.829 7.1667 0.565 0.4831
⏷ Show the Full List of 356 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 2.976 5.1505 -0.7101 0.4792
CBTCi002-A GDSC1 3.3172 5.6963 0.4889 1.9885
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-450 GDSC1 -5.8393 11.4956 -10.5068 59.6866
TE-6 GDSC2 1.1777 5.0606 -1.6288 7.3176
OE33 GDSC2 1.2912 10.5532 -4.243 20.5051
OE21 GDSC2 1.4594 8.2937 -3.0024 14.3813
KYSE-180 GDSC2 1.4845 8.6664 -3.1669 15.1526
T.T GDSC2 1.5593 3.4671 -0.6711 1.338
KYSE-410 GDSC2 1.8024 3.9944 -0.7702 1.522
KYSE-140 GDSC2 1.839 5.3561 -1.345 4.413
TE-4 GDSC2 1.8666 6.6353 -1.9209 7.592
OE19 GDSC2 2.0093 14.545 -5.6734 23.8648
EC-GI-10 GDSC2 2.0353 8.808 -2.8449 12.2602
KYSE-520 GDSC2 2.1155 8.3216 -2.5572 10.584
COLO 680N GDSC2 2.1605 3.8071 -0.5401 0.4095
TE-9 GDSC2 2.1798 3.7885 -0.5259 0.365
KYSE-450 GDSC2 2.1816 3.4421 -0.404 0.127
TE-1 GDSC2 2.2039 4.0427 -0.6096 0.5824
TE-11 GDSC2 2.212 3.7603 -0.5035 0.2999
TE-5 GDSC2 2.2131 4.0296 -0.601 0.5517
OE21 GDSC1 2.2864 8.9878 -1.7399 18.9068
KYSE-70 GDSC2 2.2929 3.6611 -0.4394 0.1553
TE-10 GDSC2 2.3231 4.1941 -0.6176 0.5408
KYSE-510 GDSC2 2.3478 3.8993 -0.5021 0.2505
KYSE-270 GDSC2 2.4225 4.908 -0.8486 1.2606
TE-1 GDSC1 2.568 4.5884 0.573 2.6369
T.T GDSC1 2.6998 6.0603 -0.021 6.4756
TE-8 GDSC2 2.8184 4.8959 -0.6791 0.4697
TE-9 GDSC1 2.9198 10.427 -1.9774 18.2749
OE33 GDSC1 2.9242 19.6989 -6.5678 32.7806
TE-8 GDSC1 2.952 6.8162 -0.2146 7.2388
TE-4 GDSC1 2.9745 5.2882 0.4878 2.488
TE-15 GDSC1 3.0329 5.9544 0.2283 4.0417
KYSE-150 GDSC1 3.3131 5.0237 0.7527 0.7263
KYSE-150 GDSC2 3.3235 13.3996 -4.1734 15.7095
TE-5 GDSC1 3.342 5.7638 0.4731 2.0431
KYSE-410 GDSC1 3.3489 6.3681 0.2206 3.5269
EC-GI-10 GDSC1 3.3916 5.2439 0.7022 0.8678
OE19 GDSC1 3.406 4.7218 0.8977 0.2271
COLO 680N GDSC1 3.4341 4.7404 0.9014 0.2099
TE-10 GDSC1 3.6464 6.346 0.381 2.1535
KYSE-180 GDSC1 3.6725 5.9113 0.5662 1.2084
KYSE-270 GDSC1 3.807 5.639 0.7231 0.5162
KYSE-510 GDSC1 3.8681 5.6513 0.7419 0.4311
TE-11 GDSC1 4.0077 5.6726 0.7859 0.2697
KYSE-140 GDSC1 4.0223 6.503 0.4889 1.2339
TE-6 GDSC1 4.1161 5.9576 0.7262 0.367
KYSE-520 GDSC1 4.2597 6.7195 0.5061 0.9785
KYSE-70 GDSC1 4.3256 5.8151 0.848 0.1002
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 58 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ES-2 GDSC2 0.7788 4.5908 -1.6831 8.5596
OVCAR-5 GDSC2 1.1739 3.2901 -0.8003 2.5028
FU-OV-1 GDSC2 1.3332 3.7448 -0.9126 2.8619
A2780 GDSC2 1.3643 3.5968 -0.829 2.3657
OVCAR-8 GDSC2 1.4972 7.0414 -2.3645 10.8692
OVCAR-3 GDSC2 1.5118 4.607 -1.1987 4.1532
SK-OV-3 GDSC2 1.5536 3.1371 -0.5401 0.7927
OV56 GDSC2 1.5572 2.5538 -0.3217 0.1446
TYK-nu GDSC2 1.5575 10.5947 -4.062 19.0967
TOV-21G GDSC2 1.5659 2.8876 -0.4388 0.4311
OAW42 GDSC2 1.5768 2.7052 -0.3677 0.2337
OVTOKO GDSC2 1.751 5.3049 -1.3742 4.7235
DOV13 GDSC2 1.8986 3.4354 -0.5076 0.4502
OVK18 GDSC2 1.9356 3.5497 -0.5351 0.5108
EFO-27 GDSC2 1.9834 3.7022 -0.5726 0.5984
TOV-112D GDSC2 2.1125 4.0392 -0.6463 0.7574
EFO-21 GDSC2 2.1209 3.9399 -0.6052 0.6176
OAW28 GDSC2 2.1214 9.8514 -3.2893 14.2883
OVKATE GDSC2 2.1384 3.8106 -0.5501 0.4467
Caov-3 GDSC2 2.1537 3.9482 -0.5948 0.5665
OV56 GDSC1 2.1709 4.1982 0.5148 3.8667
OAW28 GDSC1 2.2207 5.9659 -0.3003 9.7684
JHOS-2 GDSC2 2.2961 3.7243 -0.46 0.188
EFO-27 GDSC1 2.3535 5.1172 0.1998 5.725
DOV13 GDSC1 2.3612 4.7481 0.3781 4.4111
OAW42 GDSC1 2.4091 3.6635 0.8852 0.9907
JHOS-4 GDSC2 2.4431 4.234 -0.5851 0.3985
RMG-I GDSC2 2.4656 4.7915 -0.784 0.9869
OVISE GDSC1 2.518 8.2122 -1.1843 14.9145
OC 314 GDSC2 2.5828 3.8459 -0.4017 0.0642
OV-90 GDSC2 2.6744 4.061 -0.442 0.0908
Caov-4 GDSC1 2.7531 6.0109 0.0358 5.9491
FU-OV-1 GDSC1 2.7533 4.9064 0.5351 2.5558
Kuramochi GDSC2 2.7648 4.7531 -0.6483 0.418
TOV-21G GDSC1 2.7764 4.2481 0.8205 0.9039
JHOS-2 GDSC1 2.8723 5.4268 0.3721 3.3957
Caov-4 GDSC2 2.9915 4.8372 -0.5941 0.2361
IGROV-1 GDSC2 2.9966 14.2656 -4.8161 18.8494
SK-OV-3 GDSC1 3.112 6.4792 0.0383 5.1542
OVCAR-5 GDSC1 3.1167 5.2132 0.5905 1.6917
ES-2 GDSC1 3.1194 4.791 0.7596 0.8558
TOV-112D GDSC1 3.1346 10.5659 -1.8903 17.2132
JHOS-4 GDSC1 3.3349 7.5542 -0.3192 7.0828
EFO-21 GDSC1 3.3394 5.2498 0.6776 1.0182
OVK18 GDSC1 3.3457 5.2978 0.6617 1.0834
OV-90 GDSC1 3.4652 5.3039 0.7102 0.778
Kuramochi GDSC1 3.5147 5.6101 0.6142 1.1393
OC 314 GDSC1 3.5407 4.9225 0.8769 0.2275
OVTOKO GDSC1 3.5989 12.7086 -2.6035 19.4485
OVKATE GDSC1 3.7659 5.5048 0.7555 0.441
RMG-I GDSC1 3.8326 6.1057 0.5601 1.0939
OVCAR-4 GDSC1 3.8934 6.6706 0.3658 1.9377
TYK-nu GDSC1 3.9466 5.8022 0.7179 0.4616
OVCAR-3 GDSC1 3.9472 5.8144 0.7138 0.4729
OVCAR-4 GDSC2 3.9614 15.7678 -4.877 17.1886
A2780 GDSC1 3.9837 5.8727 0.7068 0.4754
OVISE GDSC2 4.0785 15.6086 -4.723 16.4118
OVCAR-8 GDSC1 4.7224 6.6906 0.691 0.2486
⏷ Show the Full List of 58 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-4 GDSC1 -0.0326 8.3895 -3.3957 34.6279
Panc 10.05 GDSC2 0.8465 2.884 -0.8123 3.14
KP-4 GDSC2 0.9643 5.9763 -2.2275 11.3465
PaTu 8988t GDSC2 1.0934 9.0705 -3.6594 18.4861
YAPC GDSC2 1.2789 2.6657 -0.4778 0.7843
HPAC GDSC2 1.3032 4.5626 -1.3082 5.1642
KP-2 GDSC2 1.3523 4.8742 -1.4233 5.7411
Hs 766T GDSC2 1.3667 3.2488 -0.6765 1.5872
SU.86.86 GDSC2 1.4898 3.5228 -0.7294 1.6916
MIA PaCa-2 GDSC2 1.5155 2.9163 -0.4708 0.5678
DAN-G GDSC2 1.5423 3.1942 -0.568 0.9125
CFPAC-1 GDSC2 1.6378 8.848 -3.1444 14.6768
HuP-T3 GDSC2 1.6787 4.9845 -1.2711 4.2724
QGP-1 GDSC2 1.7414 3.5087 -0.6024 0.8767
HPAF-II GDSC2 1.8553 4.0258 -0.7575 1.4101
PL4 GDSC2 1.8708 5.5722 -1.4245 4.7979
Panc 08.13 GDSC2 1.8892 7.2041 -2.1754 8.9721
HuP-T4 GDSC2 1.9153 4.3924 -0.8801 1.8999
KP-1N GDSC2 1.924 4.7898 -1.0453 2.6947
PaTu 8902 GDSC2 1.9902 3.8469 -0.6249 0.7686
BxPC-3 GDSC2 2.1933 8.3125 -2.5012 10.1266
SUIT-2 GDSC2 2.3118 5.9434 -1.3381 3.6502
PSN1 GDSC2 2.3179 4.0923 -0.5824 0.4469
Capan-2 GDSC2 2.3414 4.3627 -0.673 0.6973
SW1990 GDSC2 2.3606 4.2891 -0.6377 0.5787
PaTu 8902 GDSC1 2.4061 5.4445 0.0791 6.4764
Panc 04.03 GDSC2 2.4309 4.0421 -0.5215 0.2627
KP-2 GDSC1 2.4559 5.8407 -0.0766 7.4843
AsPC-1 GDSC2 2.4697 4.4082 -0.6379 0.5229
SU.86.86 GDSC1 2.4771 4.4442 0.586 2.72
Capan-2 GDSC1 2.5239 11.2061 -2.6577 22.7022
Capan-1 GDSC2 2.5755 5.117 -0.8625 1.189
Panc 02.03 GDSC1 2.6217 4.7704 0.5226 2.8696
SUIT-2 GDSC1 2.767 4.4739 0.7253 1.4046
MZ-PC-1 GDSC2 2.8541 5.0823 -0.7328 0.5922
KP-3 GDSC2 2.8677 4.8378 -0.6396 0.3601
Panc 02.03 GDSC2 2.9458 4.8452 -0.6134 0.2827
DAN-G GDSC1 2.9558 4.3318 0.8652 0.5558
Panc 08.13 GDSC1 3.0247 5.2168 0.5437 2.0789
PaTu 8988t GDSC1 3.0531 6.0513 0.1965 4.2134
HPAF-II GDSC1 3.1495 5.3724 0.5408 1.9222
QGP-1 GDSC1 3.1666 5.2894 0.5832 1.6683
SW1990 GDSC1 3.1762 5.8135 0.3683 2.8974
YAPC GDSC1 3.1792 4.5586 0.8707 0.3971
PL4 GDSC1 3.2424 5.8808 0.3741 2.758
HuP-T4 GDSC1 3.3027 5.8503 0.4177 2.4106
Panc 04.03 GDSC1 3.3847 5.0751 0.7628 0.6369
MIA PaCa-2 GDSC1 3.4797 4.8986 0.863 0.2806
Capan-1 GDSC1 3.4849 5.4347 0.6689 0.929
Hs 766T GDSC1 3.575 5.3127 0.7511 0.5566
HuP-T3 GDSC1 3.584 5.5525 0.6658 0.8625
Panc 03.27 GDSC2 3.6356 13.2184 -3.8804 13.8968
CFPAC-1 GDSC1 3.6931 5.307 0.7984 0.3569
AsPC-1 GDSC1 3.7451 8.0493 -0.3014 6.1208
PSN1 GDSC1 3.7866 5.592 0.7322 0.4993
KP-3 GDSC1 3.8437 6.4176 0.4438 1.6074
KP-1N GDSC1 3.8622 5.8115 0.682 0.6155
MZ-PC-1 GDSC1 3.9137 6.128 0.5856 0.9269
HPAC GDSC1 3.95 14.7339 -3.34 21.6103
Panc 10.05 GDSC1 4.1789 5.9306 0.7584 0.2729
BxPC-3 GDSC1 4.2739 6.2977 0.665 0.4578
Panc 03.27 GDSC1 4.5667 12.2619 -1.7383 12.8725
⏷ Show the Full List of 62 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC2 1.5195 3.4531 -0.685 1.4458
NCI-H2052 GDSC2 1.9202 9.9726 -3.4907 15.6963
MPP 89 GDSC2 1.9818 4.5652 -0.9192 2.0059
MSTO-211H GDSC2 1.9975 3.9304 -0.654 0.8673
IST-Mes1 GDSC2 2.1234 4.0429 -0.6431 0.7392
IST-Mes1 GDSC1 2.3665 4.633 0.4348 3.9934
MPP 89 GDSC1 2.4804 5.1401 0.2703 4.9098
NCI-H2452 GDSC2 2.6167 4.6024 -0.6511 0.4879
NCI-H2452 GDSC1 2.7774 5.6981 0.195 4.7816
NCI-H28 GDSC1 4.1599 5.9647 0.7397 0.3193
MSTO-211H GDSC1 4.3851 6.3429 0.6901 0.3523
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC2 1.7492 3.122 -0.4518 0.3702
NCI-H660 GDSC2 1.8558 3.3742 -0.5022 0.4575
PC-3 GDSC2 1.8765 5.2051 -1.255 3.8623
22Rv1 GDSC2 2.1345 4.5886 -0.8539 1.546
DU145 GDSC2 2.3856 4.1204 -0.5663 0.3769
LNCaP clone FGC GDSC2 2.6084 4.6141 -0.6586 0.5114
VCaP GDSC1 2.915 4.7333 0.6901 1.4083
PC-3 GDSC1 3.1223 8.6635 -0.9785 11.9248
DU145 GDSC1 3.6074 12.75 -2.6175 19.4894
22Rv1 GDSC1 3.6546 5.6957 0.6411 0.906
LNCaP clone FGC GDSC1 4.3957 6.7861 0.536 0.7828
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 1.648 4.5703 -1.1017 3.3926
A-253 GDSC1 3.6454 5.4732 0.7202 0.6179
Cancer Drug Sensitivity Data Curated from 114 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2058 GDSC2 0.9055 5.3641 -1.9699 9.9781
SK-MEL-1 GDSC2 0.9372 2.5483 -0.6039 1.8083
IGR-1 GDSC2 1.1227 5.8936 -2.0717 10.0591
SK-MEL-30 GDSC2 1.1827 2.7571 -0.5624 1.2627
SK-MEL-28 GDSC2 1.2474 2.4278 -0.3981 0.5045
RPMI-7951 GDSC2 1.2699 4.4049 -1.2554 4.9206
M14 GDSC2 1.2992 7.5796 -2.7691 13.5457
UACC-62 GDSC2 1.3343 2.5269 -0.399 0.4473
Mel Ho GDSC2 1.3431 3.1372 -0.6412 1.4461
GAK GDSC2 1.3576 2.7115 -0.4602 0.6478
COLO 792 GDSC2 1.405 6.6293 -2.2293 10.3166
WM35 GDSC2 1.4214 4.3367 -1.1294 3.9198
G-361 GDSC2 1.4241 5.4307 -1.6399 6.8636
SK-MEL-2 GDSC2 1.448 2.4369 -0.3209 0.1774
IGR-37 GDSC2 1.4768 3.2357 -0.6157 1.1787
SK-MEL-24 GDSC2 1.484 3.3802 -0.6722 1.4269
COLO 679 GDSC2 1.4907 3.4288 -0.6892 1.4989
UACC-257 GDSC2 1.4939 6.0113 -1.8702 8.0594
WM793 GDSC2 1.6081 9.7681 -3.6173 17.0143
SH-4 GDSC2 1.6087 3.9088 -0.8325 2.0465
A101D GDSC2 1.6096 10.3079 -3.8818 18.1965
SK-MEL-5 GDSC2 1.6465 3.4136 -0.6078 0.9799
CP66-MEL GDSC2 1.6944 3.0312 -0.4402 0.3657
Mel JuSo GDSC2 1.7879 9.3378 -3.2757 14.9746
LB2518-MEL GDSC2 1.7971 3.2203 -0.4689 0.3933
Hs 938.T GDSC2 1.804 3.2504 -0.4772 0.4133
MMAc-SF GDSC2 1.8308 3.512 -0.5645 0.6713
LB373-MEL-D GDSC2 1.8352 3.2032 -0.4477 0.3194
COLO 783 GDSC2 1.8603 3.3541 -0.4929 0.4285
VMRC-MELG GDSC2 1.8873 3.2731 -0.4528 0.3098
WT2-iPS GDSC2 1.9057 3.1947 -0.4179 0.2242
UACC-62 GDSC1 1.9151 3.9881 0.4449 5.0396
SK-MEL-3 GDSC2 1.9246 3.4872 -0.5163 0.4614
Hs 940.T GDSC2 1.9302 3.5706 -0.5451 0.5444
SK-MEL-28 GDSC1 1.945 3.6029 0.6495 3.4253
A-431 GDSC2 1.9529 3.8623 -0.6471 0.8761
CP50-MEL-B GDSC2 1.9593 3.523 -0.5156 0.4412
IPC-298 GDSC2 1.9677 7.3115 -2.1747 8.8088
A2058 GDSC1 1.9852 3.5803 0.686 3.0604
SK-MEL-31 GDSC2 2.0119 3.9849 -0.669 0.9113
LOX-IMVI GDSC2 2.0298 3.6354 -0.5289 0.4423
G-mel GDSC2 2.1442 3.9371 -0.5945 0.5711
MeWo GDSC2 2.156 3.9534 -0.5958 0.5682
HMV-II GDSC2 2.1717 5.3961 -1.1754 3.0168
HT-144 GDSC2 2.1801 9.266 -2.9661 12.5673
G-mel GDSC1 2.1922 4.2424 0.5076 3.8691
MZ-MEL-7 GDSC2 2.2345 3.8542 -0.5285 0.3486
COLO 829 GDSC2 2.2594 4.6729 -0.8294 1.326
RVH-421 GDSC2 2.2709 3.6432 -0.4411 0.163
451Lu GDSC2 2.2808 3.9547 -0.5469 0.3737
MMAc-SF GDSC1 2.2953 5.8216 -0.1774 8.6556
HT-144 GDSC1 2.3374 10.6654 -2.5329 22.7181
A-388 GDSC2 2.3718 4.2742 -0.6276 0.5439
WM115 GDSC2 2.3781 15.6908 -5.9624 23.9231
CHL-1 GDSC2 2.3968 4.4605 -0.687 0.7074
A-375 GDSC1 2.3978 4.4191 0.5515 3.109
CP50-MEL-B GDSC1 2.4041 7.8851 -1.1073 14.7703
Hs 940.T GDSC1 2.4116 5.0971 0.2468 5.2407
COLO 792 GDSC1 2.4166 4.7821 0.3967 4.1523
RPMI-7951 GDSC1 2.4293 4.8845 0.3571 4.4055
A-375 GDSC2 2.4851 4.0948 -0.52 0.2432
WM278 GDSC2 2.4902 14.0836 -5.0897 20.8927
WM115 GDSC1 2.4924 5.061 0.3145 4.5668
MZ-MEL-2 GDSC2 2.5218 6.3567 -1.4043 3.6942
COLO 679 GDSC1 2.5302 4.9341 0.3958 3.9118
A101D GDSC1 2.5675 4.2745 0.7089 1.7807
WM1552C GDSC2 2.6066 4.1199 -0.4852 0.1553
IGR-37 GDSC1 2.6218 4.0719 0.82 1.0773
SK-MEL-2 GDSC1 2.6425 3.9167 0.8909 0.7079
CP66-MEL GDSC1 2.651 4.5477 0.6357 2.0962
IST-MEL1 GDSC2 2.6776 4.4124 -0.5605 0.2623
COLO 800 GDSC2 2.6972 4.194 -0.4787 0.1292
DJM-1 GDSC2 2.706 4.6587 -0.6369 0.4148
LB373-MEL-D GDSC1 2.7146 4.3705 0.7424 1.3782
WT2-iPS GDSC1 2.7256 3.9983 0.8953 0.6148
COLO 800 GDSC1 2.7931 5.1048 0.4702 2.9015
MZ-MEL-2 GDSC1 2.8188 10.5545 -2.114 19.2661
Hs 938.T GDSC1 2.8513 4.8579 0.6071 1.9603
SK-MEL-3 GDSC1 2.9806 4.5474 0.7936 0.8308
IPC-298 GDSC1 3.0406 4.4342 0.8616 0.5107
RVH-421 GDSC1 3.0432 4.4596 0.8532 0.5393
SK-MEL-1 GDSC1 3.0838 4.5697 0.8286 0.6025
LOX-IMVI GDSC1 3.0959 4.522 0.8513 0.5111
MZ-MEL-7 GDSC1 3.1102 4.7213 0.7824 0.7667
GAK GDSC1 3.1348 4.3566 0.9259 0.2617
CHL-1 GDSC1 3.1351 5.3645 0.537 1.9629
SK-MEL-24 GDSC1 3.2021 4.7549 0.8078 0.597
WM793 GDSC1 3.2465 5.114 0.6898 1.0499
451Lu GDSC1 3.2547 4.7275 0.8388 0.456
UACC-257 GDSC1 3.2822 6.1104 0.2965 3.1669
WM1552C GDSC1 3.2988 5.044 0.7391 0.7915
MeWo GDSC1 3.3041 5.2514 0.6615 1.124
SK-MEL-31 GDSC1 3.3205 5.2619 0.6646 1.0941
SK-MEL-30 GDSC1 3.3367 4.6923 0.8826 0.289
SH-4 GDSC1 3.3603 5.2814 0.6744 1.0132
IGR-1 GDSC1 3.3628 4.9394 0.804 0.5072
LB2518-MEL GDSC1 3.3701 4.5758 0.9351 0.1622
VMRC-MELG GDSC1 3.3823 4.85 0.8438 0.3736
Mel JuSo GDSC1 3.4281 5.2484 0.7157 0.7844
M14 GDSC1 3.4302 5.2374 0.7207 0.763
COLO 783 GDSC1 3.4325 4.7727 0.8896 0.2359
DJM-1 GDSC1 3.563 5.895 0.5239 1.5152
G-361 GDSC1 3.5758 5.1476 0.8109 0.375
IST-MEL1 GDSC1 3.6152 5.7567 0.6011 1.1062
WM278 GDSC1 3.6253 5.4577 0.7179 0.6385
COLO 829 GDSC1 3.6281 6.299 0.3915 2.1203
Mel Ho GDSC1 3.6645 5.1971 0.8264 0.2981
HMV-II GDSC1 3.7424 5.8117 0.6338 0.8679
A-431 GDSC1 3.7859 5.4419 0.7853 0.3517
WM35 GDSC1 3.8203 5.7495 0.6882 0.6198
A-388 GDSC1 3.9195 6.0971 0.5996 0.8695
SK-MEL-5 GDSC1 4.553 12.9944 -2.0912 14.7048
EquiPSC Line K2 GDSC2 3.1859 5.5138 -0.7602 0.513
EquiPSC Line K2 GDSC1 3.2498 6.0657 0.2986 3.207
⏷ Show the Full List of 114 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 2.1272 5.002 0.1021 7.0461
HuTu 80 GDSC2 2.1542 4.2489 -0.7093 0.9498
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-401 GDSC2 0.7313 3.8563 -1.3579 6.6824
EW-8 GDSC2 0.9366 5.0194 -1.7784 8.759
HT-1080 GDSC2 0.965 2.9405 -0.7651 2.6531
MES-SA GDSC2 1.1363 7.8131 -3.0047 15.1854
GCT GDSC2 1.4552 8.9839 -3.3444 16.0961
VA-ES-BJ GDSC2 1.5101 9.8814 -3.7456 17.8341
Rh30 GDSC2 1.5971 3.3455 -0.6033 1.007
SW982 GDSC2 1.6473 3.2526 -0.5438 0.7315
SW684 GDSC2 1.7437 2.848 -0.3561 0.1547
KYM-1 GDSC2 1.7944 3.2166 -0.4686 0.3939
SK-UT-1 GDSC2 1.8086 3.9151 -0.7346 1.3579
TE 441.T GDSC2 2.05 3.2627 -0.3893 0.1334
VA-ES-BJ GDSC1 2.0528 6.9892 -0.9281 14.6976
RKN GDSC2 2.1089 3.5472 -0.4667 0.2569
Rh41 GDSC2 2.2325 3.9102 -0.5495 0.4009
Hs 633.T GDSC2 2.2485 3.9331 -0.5516 0.3992
MES-SA GDSC1 2.2712 5.8171 -0.1921 8.8313
SW872 GDSC2 2.395 4.1353 -0.568 0.3772
KYM-1 GDSC1 2.422 7.4418 -0.8767 13.2118
A-204 GDSC2 2.4627 8.9223 -2.6136 10.1807
MFH-ino GDSC2 2.4896 4.195 -0.5536 0.3089
G-402 GDSC1 2.5692 5.1389 0.3255 4.3193
SW982 GDSC1 2.5737 6.7711 -0.4432 9.8002
EW-8 GDSC1 2.6189 4.3865 0.6878 1.8286
Rh41 GDSC1 2.6334 4.5691 0.6171 2.2408
Rh18 GDSC1 2.6409 4.9411 0.4574 3.2662
SW684 GDSC1 2.6832 4.0369 0.862 0.8019
G-402 GDSC2 2.9071 7.8689 -1.8572 5.4478
RD GDSC2 2.9654 5.4394 -0.8202 0.7835
SW872 GDSC1 2.9768 5.3115 0.479 2.5376
Rh30 GDSC1 2.9863 4.9721 0.6265 1.6625
STS-0421 GDSC1 3.0436 6.1105 0.1647 4.4435
STS-0421 GDSC2 3.0566 5.4438 -0.7852 0.6353
A-204 GDSC1 3.2985 16.7063 -4.7915 27.9272
GCT GDSC1 3.3479 5.419 0.6152 1.2988
Hs 633.T GDSC1 3.4251 4.8416 0.8628 0.3028
SK-LMS-1 GDSC1 3.4257 12.8635 -2.8033 20.7815
G-401 GDSC1 3.4347 6.5607 0.1832 3.616
RD GDSC1 3.4707 5.8734 0.4899 1.7916
RKN GDSC1 3.523 4.6282 0.9701 0.0786
HT-1080 GDSC1 3.5516 11.72 -2.1565 17.459
MFH-ino GDSC1 3.9292 5.8212 0.7045 0.5089
SK-UT-1 GDSC1 4.1738 5.8235 0.7931 0.208
SK-LMS-1 GDSC2 4.3851 16.8741 -5.1219 17.2825
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MKN45 GDSC1 -9.1588 4.9398 -11.2743 72.7265
SNU-5 GDSC1 -8.2402 7.9944 -11.47 67.6051
MKN45 GDSC2 -7.0619 -2.2608 -7.2279 66.5639
Hs 746.T GDSC2 -6.6619 21.5622 -16.7354 53.2237
SNU-5 GDSC2 -5.6651 0.0316 -6.1912 55.0881
Hs 746.T GDSC1 -1.6359 160.7552 -80.8728 49.6476
OCUM-1 GDSC2 0.6675 3.0955 -1.0329 4.8347
SCH GDSC2 1.0026 2.5314 -0.5601 1.4836
IM95 GDSC2 1.2647 8.1063 -3.0535 15.1161
AGS GDSC2 1.3485 6.2137 -2.0674 9.5165
NUGC-3 GDSC2 1.3493 3.3459 -0.7273 1.8618
RF-48 GDSC2 1.4064 3.8206 -0.9046 2.7044
ECC10 GDSC2 1.469 4.3902 -1.1253 3.8149
23132/87 GDSC2 1.4809 2.9635 -0.5043 0.7153
SNU-1 GDSC2 1.539 4.827 -1.2834 4.5839
TGBC11TKB GDSC2 1.5458 5.0794 -1.3961 5.2139
SK-GT-2 GDSC2 1.5677 5.4437 -1.5526 6.0719
NUGC-4 GDSC2 1.589 9.0673 -3.2873 15.4968
HSC-39 GDSC2 1.6343 3.3186 -0.5755 0.8622
KATO III GDSC2 1.7595 3.9406 -0.769 1.5631
Fu97 GDSC2 1.7757 4.3831 -0.9485 2.4057
ECC12 GDSC2 1.7848 3.0359 -0.4069 0.2434
SCH GDSC1 1.8331 3.9212 0.4197 5.4626
SNU-16 GDSC2 1.8766 3.2879 -0.4623 0.338
RERF-GC-1B GDSC2 1.8884 7.8066 -2.4637 10.5585
NCI-N87 GDSC2 1.9092 10.015 -3.5193 15.855
TMK-1 GDSC1 2.0322 5.6707 -0.2926 10.2736
GCIY GDSC2 2.0935 3.8112 -0.5683 0.5213
MKN1 GDSC2 2.1291 3.4826 -0.4366 0.192
SNU-16 GDSC1 2.2435 12.5792 -3.5583 27.0568
HSC-39 GDSC1 2.3349 6.0816 -0.2757 9.2628
HGC-27 GDSC1 2.3831 4.4669 0.5211 3.3499
MKN7 GDSC2 2.4501 4.1451 -0.5507 0.3167
ECC10 GDSC1 2.572 6.7603 -0.4391 9.776
TMK-1 GDSC2 2.6185 4.4169 -0.5839 0.3285
OCUM-1 GDSC1 2.672 5.8526 0.0586 5.9755
TGBC11TKB GDSC1 2.694 5.6619 0.1608 5.202
KATO III GDSC1 2.8585 6.0415 0.0865 5.3586
IM95 GDSC1 2.9433 6.8057 -0.2152 7.2629
AGS GDSC1 3.0066 4.5866 0.7898 0.8244
NUGC-4 GDSC1 3.1078 5.2633 0.5656 1.8398
HGC-27 GDSC2 3.1215 11.4269 -3.3685 12.6046
SK-GT-2 GDSC1 3.125 5.9745 0.2708 3.5959
MKN28 GDSC2 3.3156 5.78 -0.8062 0.5707
MKN1 GDSC1 3.3759 4.8817 0.83 0.4174
NUGC-3 GDSC1 3.4607 5.6094 0.5907 1.3
23132/87 GDSC1 3.4629 4.9288 0.8462 0.3302
RF-48 GDSC1 3.6917 5.8089 0.6137 0.9878
NCI-N87 GDSC1 3.7425 6.2517 0.4638 1.6173
Fu97 GDSC1 3.7537 5.2963 0.8244 0.2705
MKN7 GDSC1 3.8294 5.6332 0.7337 0.4728
SNU-1 GDSC1 3.9944 6.5477 0.4596 1.3866
MKN28 GDSC1 4.3432 6.3999 0.6547 0.4549
RERF-GC-1B GDSC1 4.5866 7.6111 0.305 1.5304
SNG-M GDSC2 2.4961 4.0109 -0.487 0.1827
SNG-M GDSC1 2.6647 5.2447 0.3344 4.0552
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8305C GDSC2 1.1868 4.2085 -1.2165 4.8537
CGTH-W-1 GDSC2 1.738 3.161 -0.4706 0.4294
HTC-C3 GDSC2 1.7588 9.7838 -3.5148 16.1825
ASH-3 GDSC2 1.8776 3.2439 -0.446 0.2974
CAL-62 GDSC2 1.9677 3.692 -0.5753 0.6167
TT GDSC2 2.0162 3.427 -0.4588 0.273
K5 GDSC2 2.0964 4.1279 -0.6876 0.9145
IHH-4 GDSC2 2.1306 3.4117 -0.4116 0.1495
B-CPAP GDSC2 2.17 3.656 -0.4823 0.2688
TT2609-C02 GDSC2 2.1966 6.2821 -1.5543 4.9668
BHT-101 GDSC2 2.2571 4.0325 -0.5844 0.4818
WRO GDSC2 2.2606 3.7094 -0.4676 0.2112
ML-1 [Human leukemia] GDSC2 2.3064 4.116 -0.5955 0.4877
KMH-2 GDSC2 2.4731 4.3901 -0.63 0.4997
HTC-C3 GDSC1 2.4776 6.3951 -0.3281 9.245
CGTH-W-1 GDSC1 2.4896 6.7341 -0.4836 10.3171
8305C GDSC1 2.584 4.3512 0.6848 1.9016
BHT-101 GDSC1 2.5971 6.2833 -0.1935 7.9626
FTC-133 GDSC1 2.704 7.6096 -0.7579 11.6079
TT GDSC1 2.8656 5.1452 0.4918 2.6397
CAL-62 GDSC1 3.0385 5.0416 0.6232 1.6137
8505C GDSC2 3.1602 12.9865 -4.0858 15.672
ML-1 [Human leukemia] GDSC1 3.191 5.9743 0.3068 3.254
8505C GDSC1 3.2972 5.6287 0.507 1.9153
B-CPAP GDSC1 3.3152 5.006 0.7602 0.6957
WRO GDSC1 3.3922 5.1784 0.7272 0.7665
ASH-3 GDSC1 3.4377 4.8651 0.8592 0.3069
K5 GDSC1 3.4616 5.1497 0.766 0.5752
TT2609-C02 GDSC1 3.579 12.8048 -2.6645 19.7729
IHH-4 GDSC1 3.8931 5.1844 0.9109 0.0919
KMH-2 GDSC1 3.9979 6.1314 0.6185 0.7477
FTC-133 GDSC2 5.058 17.9685 -5.1997 16.3886
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 80 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-3 GDSC2 1.0869 4.4655 -1.4048 6.1748
SAT [Human HNSCC] GDSC2 1.1139 5.5234 -1.8975 9.0556
DOK GDSC2 1.4771 4.3484 -1.1014 3.6676
BICR 78 GDSC2 1.4862 4.0341 -0.9545 2.8503
SCC-4 GDSC2 1.4875 5.0105 -1.4006 5.3485
UPCI-SCC-090 GDSC2 1.5009 4.32 -1.0745 3.4795
BB30-HNC GDSC2 1.5088 7.7147 -2.6836 12.591
NCI-H3118 GDSC2 1.5305 6.7537 -2.2021 9.8823
CAL-33 GDSC2 1.5335 7.9536 -2.7825 13.0607
BICR 22 GDSC2 1.5519 8.7776 -3.1722 15.0182
SKN-3 GDSC2 1.6246 4.8234 -1.23 4.135
CAL-27 GDSC2 1.6364 3.0604 -0.4747 0.501
BB49-HNC GDSC2 1.6431 11.4211 -4.4057 20.2935
Detroit 562 GDSC2 1.7014 3.7706 -0.7271 1.4367
HO-1-N-1 GDSC2 1.7199 3.5485 -0.628 0.9957
OSC-19 GDSC2 1.817 3.7579 -0.667 1.0664
JHU-022 GDSC2 1.8292 4.4809 -0.9623 2.4041
HSC-2 GDSC2 1.8501 3.4971 -0.5507 0.6119
BICR 10 GDSC2 1.9139 6.5614 -1.8558 7.1347
PCI-04B GDSC2 1.9417 4.125 -0.7568 1.3214
PCI-15A GDSC2 1.9601 3.6739 -0.5716 0.6099
OSC-20 GDSC2 1.9824 4.0328 -0.701 1.0571
SCC-9 GDSC1 1.9954 4.6357 0.1873 6.7731
SAS GDSC2 2.0585 4.6059 -0.8978 1.8201
FaDu GDSC2 2.0618 3.876 -0.6056 0.6555
PE/CA-PJ15 GDSC2 2.0842 3.7457 -0.5478 0.4674
HO-1-u-1 GDSC2 2.1308 3.8436 -0.5653 0.4927
SCC-25 GDSC2 2.1315 4.0108 -0.6275 0.6821
JHU-029 GDSC2 2.1818 5.1204 -1.0519 2.3969
Ca9-22 GDSC2 2.2012 4.4758 -0.7776 1.1707
BICR 78 GDSC1 2.2298 4.392 0.4614 4.1154
BICR 10 GDSC1 2.2712 4.9909 0.2055 5.8913
KOSC-2 GDSC1 2.2836 5.644 -0.0996 8.1155
SCC-15 GDSC2 2.3083 5.1373 -0.9954 1.9888
CAL-27 GDSC1 2.3283 7.3183 -0.8845 13.5458
PCI-30 GDSC2 2.3437 4.3341 -0.6613 0.6592
KOSC-2 GDSC2 2.4969 4.7154 -0.7416 0.8204
JHU-011 GDSC2 2.5181 5.4741 -1.0322 1.9308
SAS GDSC1 2.5709 4.9918 0.3938 3.8405
SAT [Human HNSCC] GDSC1 2.6141 10.3818 -2.1814 20.2082
BICR 31 GDSC2 2.6568 4.2988 -0.5286 0.2113
LB771-HNC GDSC2 2.6581 15.7672 -5.7929 22.8218
HSC-4 GDSC1 2.6618 10.9225 -2.4126 21.1785
SCC-9 GDSC2 2.666 4.6458 -0.6476 0.4573
PCI-15A GDSC1 2.7215 5.3831 0.3051 4.1395
KON GDSC2 2.7219 4.587 -0.6054 0.3382
BB30-HNC GDSC1 2.7731 6.766 -0.3064 8.3147
PCI-06A GDSC2 2.8297 4.6343 -0.5823 0.2588
BHY GDSC2 2.9052 4.5462 -0.5253 0.1517
HSC-3 GDSC1 2.911 12.717 -3.1116 23.4611
PCI-38 GDSC1 2.9903 5.241 0.516 2.2929
DOK GDSC1 2.9937 5.8335 0.2599 3.9074
HSC-2 GDSC1 3.0631 4.3132 0.9144 0.3258
SCC-25 GDSC1 3.1069 6.0498 0.2276 3.9079
PCI-06A GDSC1 3.126 5.5218 0.4666 2.383
FaDu GDSC1 3.2437 4.5737 0.8899 0.3097
BB49-HNC GDSC1 3.3263 9.8257 -1.3977 13.949
SCC-15 GDSC1 3.354 12.2008 -2.531 19.7683
PE/CA-PJ15 GDSC1 3.4004 5.4377 0.6312 1.1704
SCC-4 GDSC1 3.5057 5.4576 0.6689 0.9118
JHU-022 GDSC1 3.5361 10.0961 -1.3853 13.3383
HO-1-u-1 GDSC1 3.5671 5.5215 0.6704 0.8569
PCI-30 GDSC1 3.5704 5.8047 0.5628 1.321
UPCI-SCC-090 GDSC1 3.6001 5.5071 0.6894 0.7587
HO-1-N-1 GDSC1 3.6043 5.879 0.5488 1.3534
Detroit 562 GDSC1 3.6899 5.1826 0.8407 0.2562
OSC-19 GDSC1 3.7134 5.9174 0.5815 1.105
BHY GDSC1 3.7307 5.5446 0.7277 0.5432
OSC-20 GDSC1 3.7501 5.607 0.7126 0.5809
PCI-04B GDSC1 3.9541 6.03 0.6384 0.7065
Ca9-22 GDSC1 3.9569 5.9785 0.6583 0.638
NCI-H3118 GDSC1 4.0317 6.0723 0.6534 0.611
JHU-011 GDSC1 4.0335 6.7437 0.4003 1.6203
KON GDSC1 4.0566 18.1288 -4.9256 26.4791
JHU-029 GDSC1 4.1768 6.6707 0.4902 1.1019
SKN-3 GDSC1 4.2378 6.3178 0.6443 0.5314
LB771-HNC GDSC1 4.4097 6.8281 0.5262 0.8074
CAL-33 GDSC1 4.4497 6.4886 0.6629 0.3919
HSC-4 GDSC2 4.4761 13.8506 -3.6458 11.43
BICR 22 GDSC1 4.7797 17.0123 -3.8619 21.5653
⏷ Show the Full List of 80 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC2 1.0703 2.812 -0.646 1.8333
CAL-29 GDSC2 1.2647 3.0115 -0.6282 1.4796
BFTC-905 GDSC2 1.4635 2.9121 -0.4919 0.6824
639V GDSC2 1.4839 3.1993 -0.5975 1.0915
HT-1197 GDSC2 1.5765 5.4257 -1.5385 5.974
5637 GDSC2 1.6283 5.3487 -1.4698 5.4828
SW780 GDSC2 1.7252 6.6393 -2.0154 8.41
SW780 GDSC1 1.7347 3.5136 0.5481 4.7599
RT-4 GDSC2 1.8906 4.4256 -0.9066 2.0545
RT-112 GDSC2 1.9388 3.4745 -0.5059 0.4246
647V GDSC2 1.9614 10.5859 -3.7607 16.8349
TCCSUP GDSC2 2.0613 6.2534 -1.6216 5.5606
UM-UC-3 GDSC2 2.0764 3.9678 -0.6344 0.7413
J82 GDSC2 2.3572 5.0055 -0.9178 1.5998
RT-112 GDSC1 2.4425 4.2681 0.6446 2.3968
SW1710 GDSC2 2.4571 4.3182 -0.6101 0.4549
CAL-29 GDSC1 2.505 5.1379 0.2866 4.7367
HT-1376 GDSC2 2.5369 4.3621 -0.5952 0.3842
UM-UC-3 GDSC1 2.5976 4.6037 0.5826 2.5214
RT-4 GDSC1 2.6565 5.1165 0.3876 3.7073
639V GDSC1 2.6855 3.9432 0.8994 0.6319
HT-1197 GDSC1 2.8337 5.2772 0.4167 3.1748
KU-19-19 GDSC1 2.8796 4.2388 0.8687 0.5995
5637 GDSC1 2.9928 5.2225 0.5252 2.2347
SW1710 GDSC1 3.0192 5.3345 0.4912 2.3974
TCCSUP GDSC1 3.034 6.6575 -0.09 6.1922
T24 GDSC2 3.0802 4.6941 -0.5146 0.1104
HT-1376 GDSC1 3.3527 5.6374 0.5299 1.7232
J82 GDSC1 3.4789 5.7643 0.5376 1.5389
647V GDSC1 3.4975 4.6456 0.9557 0.1008
T24 GDSC1 4.1322 5.984 0.7228 0.3689
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVCA420 GDSC2 1.0317 6.277 -2.3257 11.7455
PWR-1E GDSC2 1.1303 4.0652 -1.1854 4.7818
NEC8 GDSC2 1.182 3.4597 -0.8723 2.886
HeLa GDSC2 1.2104 2.8531 -0.5888 1.356
TC-YIK GDSC2 1.3045 3.7206 -0.9184 2.94
HEC-1 GDSC2 1.3729 4.4534 -1.2131 4.482
PA-1 GDSC2 1.5491 7.0464 -2.3306 10.5637
OVCA433 GDSC2 1.5735 3.5423 -0.6953 1.4328
LB831-BLC GDSC2 1.6033 4.151 -0.9408 2.6043
JEG-3 GDSC2 1.6658 3.435 -0.6074 0.9613
C-33 A GDSC2 1.6899 3.9845 -0.8226 1.8952
NT2-D1 GDSC2 1.7985 3.3165 -0.504 0.4951
BPH-1 GDSC2 1.8172 10.5737 -3.8595 17.6058
SiHa GDSC2 1.8189 2.9938 -0.3795 0.1758
HT-3 GDSC2 1.8763 7.3249 -2.2415 9.3652
OMC-1 [Human cervical carcinoma] GDSC2 1.8922 3.4481 -0.5149 0.4748
NCC-IT GDSC2 1.9085 3.5731 -0.555 0.5888
SKG-IIIa GDSC2 1.9195 3.5415 -0.5386 0.5306
MS751 GDSC2 1.9294 5.6182 -1.4106 4.6233
SW954 GDSC1 1.9827 6.596 -0.7867 13.9646
SW962 GDSC1 1.997 4.282 0.3597 5.4609
HEY GDSC2 2.0034 4.2743 -0.7882 1.3946
C-4-I GDSC2 2.013 3.7669 -0.5847 0.6187
SW954 GDSC2 2.0636 3.7728 -0.5661 0.5315
DoTc2 4510 GDSC2 2.088 3.7859 -0.5611 0.5033
SW962 GDSC2 2.1658 3.9142 -0.5773 0.5085
SKN GDSC1 2.1888 11.9288 -3.2776 26.223
JHOS-3 GDSC2 2.2887 4.2576 -0.6553 0.6734
CAL-39 GDSC2 2.2919 4.7305 -0.8375 1.3295
JAR GDSC2 2.3014 3.9069 -0.522 0.3078
KGN GDSC2 2.346 4.8025 -0.8415 1.2978
OVCA420 GDSC1 2.4422 8.241 -1.2541 15.5768
DSH1 GDSC2 2.5513 4.2554 -0.5519 0.2847
SKN GDSC2 2.5731 4.6585 -0.6889 0.6128
TC-YIK GDSC1 2.6198 5.413 0.2302 4.8785
SW756 GDSC2 2.6338 11.2044 -3.5882 14.5877
C-33 A GDSC1 2.6445 5.0352 0.4173 3.5294
PEO1 GDSC2 2.6489 4.732 -0.6857 0.5649
UWB1.289 GDSC2 2.6594 5.1391 -0.8345 1.025
SiHa GDSC1 2.6942 4.5995 0.6361 2.025
ACC-OV7 GDSC1 2.7233 10.9673 -2.3885 20.8838
ACC-OV7 GDSC2 2.8132 5.318 -0.8375 0.9307
OV17R GDSC2 2.8248 5.1038 -0.7524 0.6617
HeLa GDSC1 2.8797 3.8231 1.0186 0.1408
SiSo GDSC2 2.9154 8.8988 -2.3183 7.8147
ME-180 GDSC2 2.928 5.1181 -0.717 0.5165
JEG-3 GDSC1 2.9893 4.7635 0.7126 1.2053
OV17R GDSC1 2.9964 5.9925 0.1904 4.3639
PWR-1E GDSC1 3.2584 5.3179 0.6147 1.3974
KGN GDSC1 3.2667 6.4893 0.1225 4.2966
OVMIU GDSC2 3.2817 5.9842 -0.8945 0.8277
HEC-1 GDSC1 3.3115 4.926 0.7885 0.5931
BPH-1 GDSC1 3.3654 9.1124 -1.0302 11.6291
Ca Ski GDSC2 3.3804 5.663 -0.7399 0.395
HT-3 GDSC1 3.3843 5.6557 0.5374 1.6469
NEC8 GDSC1 3.4198 4.8599 0.8544 0.327
SW756 GDSC1 3.469 5.1896 0.7543 0.6113
SKG-IIIa GDSC1 3.5015 5.2969 0.7277 0.6856
SiSo GDSC1 3.563 6.0381 0.4666 1.8035
UWB1.289 GDSC1 3.5708 6.2864 0.369 2.3167
NT2-D1 GDSC1 3.5738 5.4632 0.6951 0.7563
JAR GDSC1 3.5962 5.2493 0.7824 0.4468
OVMIU GDSC1 3.6876 6.0948 0.5011 1.4947
DoTc2 4510 GDSC1 3.7016 5.7064 0.6565 0.8107
JHOS-3 GDSC1 3.7059 5.9848 0.5522 1.2397
C-4-I GDSC1 3.7501 5.2626 0.8347 0.2492
ME-180 GDSC1 3.7667 6.4077 0.4127 1.8444
CAL-39 GDSC1 3.8917 6.042 0.6088 0.8546
MS751 GDSC1 3.9573 5.5936 0.795 0.2666
DSH1 GDSC1 4.0017 5.8 0.7393 0.38
OVCA433 GDSC1 4.0836 5.9793 0.7065 0.4304
HEY GDSC1 4.1374 6.4907 0.5416 0.9323
PEO1 GDSC1 4.3675 6.9014 0.4822 0.9918
OMC-1 [Human cervical carcinoma] GDSC1 4.4017 6.2728 0.7203 0.2823
LB831-BLC GDSC1 4.4457 6.3335 0.7151 0.2795
Ca Ski GDSC1 4.5906 7.018 0.5279 0.6981
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 ClinicalTrials.gov (NCT02127710) A Phase II Trial to Evaluate the Efficacy of AZD6094 (HMPL-504) in Patients With Papillary Renal Cell Carcinoma (PRCC). U.S. National Institutes of Health.
3 Dictamnine, a novel c-Met inhibitor, suppresses the proliferation of lung cancer cells by downregulating the PI3K/AKT/mTOR and MAPK signaling pathways. Biochem Pharmacol. 2022 Jan;195:114864. doi: 10.1016/j.bcp.2021.114864. Epub 2021 Nov 30.