Details of the Drug

General Information of Drug (ID: DMAS4TV)

Drug Name
GW441756
Synonyms GW-441756; GW 441756
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C17H13N3O
Canonical SMILES
CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O
InChI
1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-
InChIKey
NXNQLECPAXXYTR-LCYFTJDESA-N
Cross-matching ID
PubChem CID
9943465
ChEBI ID
CHEBI:92072
CAS Number
504433-24-3
TTD ID
D0J4YA

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 3.3415 9.0951 -1.3022 8.7707
H-EMC-SS GDSC1; GDSC2 0.0867 12.7689 -5.6619 33.947
CHSA8926 GDSC1; GDSC2 1.462 4.1236 -0.1955 6.3256
SK-PN-DW GDSC1; GDSC2 1.7282 5.3761 -0.6148 8.2652
TC-71 GDSC1; GDSC2 1.8372 4.6995 -0.207 5.5208
EW-24 GDSC1; GDSC2 1.9244 3.8787 0.2386 2.7033
A-673 GDSC1; GDSC2 2.1556 3.98 0.3272 1.8502
SJSA-1 GDSC1; GDSC2 2.1811 5.856 -0.5282 6.7112
CAL-78 GDSC1; GDSC2 2.1874 12.7185 -3.9015 23.2694
NOS-1 [Human HNSCC] GDSC1; GDSC2 2.1987 4.475 0.1307 2.8418
CAL-72 GDSC1; GDSC2 2.3509 6.3445 -0.6475 7.0597
MG-63 GDSC1; GDSC2 2.3966 5.0076 0.0057 3.2077
ES4 GDSC1; GDSC2 2.5023 11.5119 -3.0625 19.2337
ES5 GDSC1; GDSC2 2.7468 5.9756 -0.2269 3.9162
ES8 GDSC1; GDSC2 2.7569 7.7705 -1.0568 8.5788
SaOS-2 GDSC1; GDSC2 2.7654 4.5533 0.3908 0.8831
EW-7 GDSC1; GDSC2 2.9311 6.6609 -0.429 4.7213
CHSA0011 GDSC1; GDSC2 2.9425 9.363 -1.6943 11.6756
HuO9 GDSC1; GDSC2 2.9625 5.6841 0.0205 2.3178
ES7 GDSC1; GDSC2 3.0181 7.719 -0.8635 6.981
EW-13 GDSC1; GDSC2 3.0993 5.2249 0.2758 1.0493
CADO-ES1 GDSC1; GDSC2 3.1349 4.6867 0.4935 0.3368
EW-1 GDSC1; GDSC2 3.2203 11.6258 -2.5955 15.507
EW-22 GDSC1; GDSC2 3.2284 5.4336 0.2513 1.038
EW-16 GDSC1; GDSC2 3.2931 5.6497 0.1952 1.1993
HOS GDSC1; GDSC2 3.3192 8.1531 -0.8783 6.5177
EW-12 GDSC2 3.3233 5.4469 0.2874 0.8391
ES1 GDSC1; GDSC2 3.409 11.0926 -2.2072 13.2735
SK-ES-1 GDSC1; GDSC2 3.4884 5.4975 0.3366 0.5846
U2OS GDSC1; GDSC2 3.4892 5.8751 0.1938 1.0487
EW-11 GDSC1; GDSC2 3.4934 6.314 0.0214 1.725
G-292 clone A141B1 GDSC1; GDSC2 3.4944 5.281 0.4177 0.3711
U-CH2 GDSC2 3.5153 5.207 0.4518 0.289
HuO-3N1 GDSC1; GDSC2 3.6275 5.6721 0.3278 0.5387
MHH-ES-1 GDSC1; GDSC2 3.7472 6.106 0.2151 0.8029
EW-18 GDSC1; GDSC2 3.7871 5.5653 0.4262 0.2553
EW-3 GDSC1; GDSC2 3.9532 6.0674 0.311 0.4384
ES6 GDSC1; GDSC2 4.2549 6.397 0.3071 0.3411
CHSA0108 GDSC1; GDSC2 4.3138 6.0747 0.4381 0.1277
NY GDSC1; GDSC2 4.6189 6.6701 0.3433 0.1921
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 -5.9417 -4.4944 -5.9417 69.5938
VL51 GDSC1; GDSC2 -2.4779 3.9002 -3.8487 39.6219
OCI-Ly19 GDSC1; GDSC2 -2.0732 1.1204 -2.3876 32.3757
MV4-11 GDSC1; GDSC2 -1.6842 0.6582 -1.8436 27.7543
DND-41 GDSC1; GDSC2 -1.6539 2.1493 -2.275 29.7741
Granta-519 GDSC1; GDSC2 -1.595 4.2904 -3.1078 33.0262
EJM GDSC1; GDSC2 -1.5374 1.0801 -1.7915 26.7825
VAL GDSC1; GDSC2 -0.4962 3.5699 -1.6752 21.6671
OCI-AML-5 GDSC1; GDSC2 -0.178 3.0308 -1.1098 17.1944
MOLM-13 GDSC1; GDSC2 0.0157 1.6373 -0.2967 11.6096
AMO1 GDSC1; GDSC2 1.1741 4.1551 -0.4349 8.5837
SU-DHL-5 GDSC1; GDSC2 1.2185 6.161 -1.4008 14.3342
EoL-1 GDSC1; GDSC2 1.2978 2.8785 0.2959 3.6635
OCI-Ly7 GDSC1; GDSC2 1.3356 3.146 0.1922 4.2179
ATN-1 GDSC1; GDSC2 1.476 5.5302 -0.8816 10.5351
YT GDSC1; GDSC2 1.5896 2.9046 0.4827 1.9055
Karpas-422 GDSC1; GDSC2 1.6488 3.3013 0.3347 2.6573
WSU-NHL GDSC1; GDSC2 1.6596 3.6382 0.1818 3.5471
EM-2 GDSC1; GDSC2 1.7316 3.9782 0.0676 4.0845
L-363 GDSC1; GDSC2 1.7401 3.1608 0.4563 1.7932
Ramos.2G6.4C10 GDSC1; GDSC2 1.7487 3.1589 0.4623 1.7461
SKM-1 GDSC1; GDSC2 1.8017 4.1268 0.0436 4.0823
SU-DHL-10 GDSC2 1.8034 4.1138 0.051 4.0348
SIG-M5 GDSC2 1.8283 6.8917 -1.2873 12.032
JJN-3 GDSC1; GDSC2 1.8422 6.8446 -1.2536 11.8019
BV-173 GDSC1; GDSC2 1.8889 3.8773 0.2174 2.8885
KY821 GDSC1; GDSC2 1.9204 3.4663 0.4231 1.6894
SCC-3 GDSC2 1.9438 5.0775 -0.3159 5.9479
Karpas-299 GDSC1; GDSC2 1.959 3.7475 0.3193 2.1922
HDLM-2 GDSC1; GDSC2 2.0137 5.9323 -0.6809 7.9943
A3/Kawakami GDSC1; GDSC2 2.0146 2.9402 0.6895 0.364
P12-Ichikawa GDSC1; GDSC2 2.0253 5.8128 -0.6147 7.5699
MOLM-16 GDSC1; GDSC2 2.0284 3.986 0.252 2.4504
ALL-PO GDSC1; GDSC2 2.0527 5.1423 -0.2732 5.4594
SUP-M2 GDSC1; GDSC2 2.1097 3.4627 0.5244 0.9434
Mono-Mac-6 GDSC1; GDSC2 2.13 4.991 -0.1507 4.578
Reh GDSC1; GDSC2 2.1447 3.4877 0.5311 0.877
L-1236 GDSC1; GDSC2 2.1544 5.57 -0.4093 6.06
SUP-B8 GDSC1; GDSC2 2.1563 5.036 -0.1549 4.552
MM1.S GDSC1; GDSC2 2.1708 3.9385 0.3536 1.693
TALL-1 [Human adult T-ALL] GDSC2 2.1718 7.0046 -1.0906 10.0546
PF-382 GDSC1; GDSC2 2.1863 4.085 0.2979 1.9585
CTV-1 GDSC1; GDSC2 2.1914 5.5064 -0.3544 5.6579
EHEB GDSC1 2.1954 5.7111 -0.4492 7.6924
P32/ISH GDSC1; GDSC2 2.232 3.4191 0.5986 0.5277
Karpas-1106P GDSC1; GDSC2 2.2353 4.0522 0.3389 1.6805
OCI-M1 GDSC1; GDSC2 2.2539 3.5355 0.5627 0.645
MOLT-4 GDSC1; GDSC2 2.2567 4.1334 0.3152 1.7716
RPMI-8866 GDSC1; GDSC2 2.2575 4.0784 0.3393 1.6491
RPMI-8226 GDSC1; GDSC2 2.2656 4.5946 0.1157 2.8151
MC116 GDSC1; GDSC2 2.2691 3.1627 0.7092 0.1762
CESS GDSC1; GDSC2 2.2712 6.261 -0.6613 7.3092
DEL GDSC1; GDSC2 2.3445 6.037 -0.5054 6.2379
SU-DHL-8 GDSC2 2.3524 4.5123 0.2017 2.2221
ME1 GDSC1; GDSC2 2.3572 3.5833 0.5892 0.4714
P31/FUJ GDSC1; GDSC2 2.3631 3.6589 0.5627 0.5593
MHH-PREB-1 GDSC1; GDSC2 2.3631 4.5958 0.1708 2.3686
HL-60 GDSC1; GDSC2 2.3706 4.0552 0.407 1.1905
A4/Fukuda GDSC1; GDSC2 2.3777 4.8268 0.0762 2.8528
Kasumi-1 GDSC1; GDSC2 2.378 4.4118 0.2594 1.8901
GA-10 GDSC1; GDSC2 2.3845 4.3145 0.3047 1.6568
SU-DHL-1 GDSC2 2.4045 9.9952 -2.3875 16.4277
L-540 GDSC1; GDSC2 2.4195 4.7937 0.1147 2.5814
Hs 445 GDSC2 2.4312 5.0507 0.0065 3.1477
KMOE-2 GDSC1; GDSC2 2.4397 4.118 0.4147 1.0836
BALL-1 GDSC1; GDSC2 2.4529 4.0035 0.4672 0.8505
KM-H2 GDSC1; GDSC2 2.4546 4.3655 0.3191 1.5018
DoHH2 GDSC1; GDSC2 2.4591 3.673 0.5977 0.3818
NKM-1 GDSC1; GDSC2 2.4637 4.8505 0.1143 2.5184
JVM-3 GDSC1 2.4814 4.2782 0.3689 1.547
TK [Human B-cell lymphoma] GDSC1; GDSC2 2.4819 4.2123 0.3963 1.1207
NB4 GDSC1; GDSC2 2.4942 3.6127 0.6338 0.2644
Ku812 GDSC1; GDSC2 2.5134 4.3687 0.3472 1.3053
Karpas-620 GDSC1; GDSC2 2.5148 4.0712 0.4684 0.7919
RCH-ACV GDSC1; GDSC2 2.5849 4.5401 0.3112 1.3902
MOLP-8 GDSC1; GDSC2 2.5927 4.6884 0.2531 1.6509
H9 GDSC1; GDSC2 2.6109 4.5521 0.319 1.3271
OCI-AML-2 GDSC1; GDSC2 2.6158 3.7443 0.6331 0.2171
KOPN-8 GDSC1; GDSC2 2.6207 4.9489 0.1565 2.0851
WIL2 NS GDSC1; GDSC2 2.6824 4.2048 0.4898 0.5877
MHH-CALL-2 GDSC1; GDSC2 2.6908 4.1111 0.5287 0.4579
IM-9 GDSC1; GDSC2 2.7107 3.8672 0.6251 0.2009
OCI-AML-3 GDSC1; GDSC2 2.7328 4.1473 0.5323 0.4236
PL-21 GDSC1; GDSC2 2.734 5.2884 0.0702 2.3674
NU-DUL-1 GDSC1; GDSC2 2.7729 4.4397 0.4384 0.7021
NCI-H929 GDSC1; GDSC2 2.7774 4.3403 0.4783 0.5637
Daudi GDSC1; GDSC2 2.7849 4.4561 0.4373 0.6974
DG-75 GDSC1; GDSC2 2.8058 5.3006 0.1028 2.1135
JURL-MK1 GDSC1; GDSC2 2.8157 4.3823 0.4784 0.5398
LAMA-84 GDSC1; GDSC2 2.8233 4.8458 0.3006 1.1937
RL GDSC1; GDSC2 2.8351 4.0769 0.5974 0.2164
BL-41 GDSC1; GDSC2 2.8542 4.0947 0.5982 0.2084
BE-13 GDSC1; GDSC2 2.8606 4.6849 0.3815 0.8423
HT GDSC1; GDSC2 2.9204 4.7166 0.3952 0.7479
HEL GDSC1; GDSC2 2.9295 4.2316 0.5779 0.2249
697 GDSC1; GDSC2 2.9345 4.5407 0.4678 0.5026
SR GDSC1; GDSC2 2.9355 4.32 0.5488 0.2865
NK-92MI GDSC2 2.9379 4.8595 0.3473 0.9085
Namalwa GDSC1; GDSC2 2.9425 4.2901 0.5621 0.2539
SU-DHL-4 GDSC1; GDSC2 2.948 4.4512 0.5062 0.3871
CMK GDSC1 2.9561 3.9259 0.6914 0.0652
WSU-DLCL2 GDSC1; GDSC2 2.9633 4.1893 0.605 0.1636
ALL-SIL GDSC1; GDSC2 2.9645 4.8399 0.3667 0.817
JeKo-1 GDSC1; GDSC2 2.966 4.1917 0.6052 0.1626
TUR GDSC1; GDSC2 2.9688 4.3684 0.5442 0.2842
MOLT-16 GDSC1; GDSC2 2.9704 4.2629 0.582 0.2036
OPM-2 GDSC1; GDSC2 3.0005 4.4113 0.5408 0.2797
CTB-1 GDSC1; GDSC2 3.0044 5.3447 0.1835 1.5152
CA46 GDSC1; GDSC2 3.0427 4.736 0.4391 0.5276
KMS-12-BM GDSC1; GDSC2 3.0499 4.8931 0.3829 0.7011
SU-DHL-6 GDSC1; GDSC2 3.0565 4.5282 0.5204 0.3049
MOLT-13 GDSC1; GDSC2 3.0632 4.7274 0.4505 0.4831
Jiyoye GDSC1; GDSC2 3.0782 4.8414 0.4142 0.5827
CCRF-CEM GDSC1; GDSC2 3.0889 4.5578 0.5221 0.2886
KE-37 GDSC1; GDSC2 3.1029 4.5765 0.5207 0.2865
SK-MM-2 GDSC1; GDSC2 3.1098 5.1392 0.3139 0.8989
P30/OHK GDSC1; GDSC2 3.1134 4.8503 0.4253 0.5293
LP-1 GDSC1; GDSC2 3.1157 5.1051 0.3297 0.8382
BC-3 GDSC2 3.1202 4.5184 0.5476 0.2242
RC-K8 GDSC1; GDSC2 3.1311 4.4735 0.5672 0.1846
SUP-B15 GDSC1; GDSC2 3.1388 4.5474 0.5443 0.2249
L-428 GDSC1; GDSC2 3.1402 4.9548 0.3972 0.5987
K-562 GDSC1; GDSC2 3.1491 5.4859 0.1946 1.3282
ST486 GDSC1; GDSC2 3.1491 4.5241 0.5562 0.1994
MLMA GDSC1; GDSC2 3.1664 5.2506 0.2954 0.9234
Karpas-231 GDSC1; GDSC2 3.192 4.388 0.6179 0.0965
RPMI-8402 GDSC1; GDSC2 3.2444 5.3198 0.3024 0.8422
BONNA-12 GDSC2 3.2466 5.7151 0.1477 1.4312
BC-1 GDSC1; GDSC2 3.2478 5.0711 0.3976 0.5371
MY-M12 GDSC1; GDSC2 3.2491 4.9049 0.4588 0.3731
NOMO-1 GDSC1; GDSC2 3.2718 4.3937 0.6431 0.0595
SU-DHL-16 GDSC1; GDSC2 3.2798 4.6424 0.5624 0.1556
ML-2 GDSC1; GDSC2 3.2802 4.7565 0.5231 0.2227
U266B1 GDSC1; GDSC2 3.2912 4.9833 0.4468 0.3848
DB GDSC1; GDSC2 3.3004 4.9562 0.4601 0.349
RS4;11 GDSC1; GDSC2 3.3179 5.2177 0.3716 0.5749
Raji GDSC1; GDSC2 3.3221 4.4447 0.6432 0.0541
SUP-T1 GDSC1; GDSC2 3.3229 5.0312 0.4417 0.3836
THP-1 GDSC1; GDSC2 3.3485 4.8239 0.5245 0.201
KCL-22 GDSC1; GDSC2 3.3564 5.2398 0.3789 0.5336
HH [Human lymphoma] GDSC1; GDSC2 3.3632 5.5229 0.2752 0.8531
GR-ST GDSC1; GDSC2 3.3773 5.7377 0.1982 1.1188
Loucy GDSC1; GDSC2 3.3977 4.865 0.528 0.1824
U-698-M GDSC1; GDSC2 3.4132 5.2917 0.3824 0.4955
MHH-CALL-4 GDSC2 3.4261 5.5124 0.3056 0.7129
Sc-1 GDSC1 3.4307 5.1461 0.4417 0.4244
HAL-01 GDSC1; GDSC2 3.4532 5.5253 0.312 0.6772
SUP-HD1 GDSC1; GDSC2 3.4709 5.5135 0.3236 0.6321
NALM-6 GDSC1; GDSC2 3.4756 5.0804 0.4815 0.2431
MN-60 GDSC1; GDSC2 3.5048 5.4006 0.3786 0.4624
Karpas-45 GDSC1; GDSC2 3.5069 5.2422 0.4362 0.3247
GDM-1 GDSC1; GDSC2 3.5085 5.5955 0.3083 0.6564
MEG-01 GDSC1; GDSC2 3.5107 5.5096 0.3411 0.5604
Jurkat GDSC1; GDSC2 3.5114 4.8006 0.5893 0.0809
CRO-AP2 GDSC1; GDSC2 3.5193 5.5649 0.3241 0.6041
CML-T1 GDSC1; GDSC2 3.5208 4.8186 0.5865 0.0825
RPMI-6666 GDSC1; GDSC2 3.56 4.8422 0.5919 0.0724
EB2 GDSC1; GDSC2 3.621 5.1867 0.4971 0.1784
Farage GDSC1; GDSC2 3.6496 5.2301 0.4924 0.1792
LC4-1 GDSC1; GDSC2 3.6622 5.8308 0.2832 0.6458
HC-1 GDSC1; GDSC2 3.6832 5.5487 0.3937 0.3539
ARH-77 GDSC1; GDSC2 3.7862 5.38 0.4895 0.1546
KG-1 GDSC1; GDSC2 3.9269 5.8495 0.3782 0.3042
JSC-1 GDSC1; GDSC2 4.0644 20.62 -6.388 26.238
ROS-50 GDSC1; GDSC2 4.096 5.8984 0.422 0.1869
JVM-2 GDSC1; GDSC2 4.2627 6.6167 0.2322 0.4996
KMS-11 GDSC1; GDSC2 4.3621 6.307 0.3766 0.1968
QIMR-WIL GDSC1; GDSC2 4.7616 6.8084 0.3461 0.1634
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-51 GDSC1; GDSC2 1.9331 3.9032 0.2327 2.7219
KYSE-50 GDSC1; GDSC2 2.3267 4.2087 0.3198 1.6561
OACM5.1 C GDSC1; GDSC2 2.7169 4.9511 0.2053 1.7301
HCE-4 GDSC1; GDSC2 3.1697 5.7459 0.0986 1.7173
ESO-26 GDSC1; GDSC2 3.1727 5.2058 0.3154 0.8474
KYAE-1 GDSC1; GDSC2 3.391 4.9626 0.4917 0.2493
TE-12 GDSC1; GDSC2 3.4657 6.7178 -0.1596 2.5681
KYSE-220 GDSC1; GDSC2 3.4994 5.3191 0.4059 0.3968
SK-GT-4 GDSC1; GDSC2 3.7416 9.7037 -1.3347 8.2039
FLO-1 GDSC1; GDSC2 4.1396 13.0244 -2.64 13.7999
OACP4 C GDSC1; GDSC2 5.1707 18.3306 -4.4842 18.8839
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 2.3641 5.0018 -0.0108 3.3527
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-DZ GDSC1; GDSC2 1.2171 5.2063 -0.9251 11.5053
SJNB-10 GDSC1; GDSC2 1.2944 3.0453 0.2111 4.2015
SJNB-14 GDSC1; GDSC2 1.7322 5.479 -0.6624 8.5463
SiMa GDSC1 1.7703 9.4241 -2.5885 22.2554
SJNB-17 GDSC1; GDSC2 2.0022 4.6375 -0.0667 4.3338
SJNB-7 GDSC1; GDSC2 2.0378 6.718 -1.047 10.1151
SK-N-BE(2)-M17 GDSC1; GDSC2 2.1008 5.6823 -0.4994 6.7113
SJNB-6 GDSC1; GDSC2 2.1544 5.0276 -0.1522 4.5395
NB69 GDSC1; GDSC2 2.155 4.4819 0.1015 3.0782
MHH-NB-11 GDSC1; GDSC2 2.2055 3.9639 0.3611 1.6083
KP-N-YN GDSC1; GDSC2 2.4848 6.1872 -0.4852 5.8422
CHP-212 GDSC1; GDSC2 2.5985 4.627 0.2818 1.5099
SK-N-MC-IXC GDSC1; GDSC2 2.6044 3.663 0.6575 0.17
GOTO GDSC1; GDSC2 2.724 11.8089 -3.0436 18.6192
NB1 GDSC1; GDSC2 2.7671 5.2656 0.0975 2.1881
SK-N-AS GDSC1; GDSC2 2.8321 4.5544 0.4197 0.7253
IMR-5 GDSC1; GDSC2 2.8464 4.6074 0.4054 0.7657
CHP-126 GDSC1; GDSC2 2.9397 4.5118 0.4807 0.462
TGW GDSC1; GDSC2 2.9686 6.0852 -0.15 3.1687
Kelly GDSC1; GDSC2 2.9774 4.5053 0.4981 0.3948
NH-12 GDSC1; GDSC2 3.0035 5.016 0.3151 0.9776
SJNB-13 GDSC1; GDSC2 3.0948 4.6909 0.4765 0.3966
GI-ME-N GDSC1; GDSC2 3.3084 8.5912 -1.0876 7.6746
LA-N-6 GDSC1; GDSC2 3.3533 5.0889 0.4326 0.3931
NB(TU)1 GDSC1 3.3623 5.0866 0.437 0.4719
SJNB-5 GDSC1; GDSC2 3.3664 5.0627 0.4471 0.3532
KP-N-YS GDSC1; GDSC2 3.5189 5.3591 0.3991 0.4053
SK-N-SH GDSC1; GDSC2 3.6254 5.8026 0.2788 0.679
KP-N-RT-BM-1 GDSC2 3.6786 5.9694 0.2381 0.7722
SJNB-12 GDSC1; GDSC2 3.7913 5.9511 0.2903 0.5602
SK-N-FI GDSC1; GDSC2 4.3473 13.8368 -2.8888 14.4787
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; GDSC2 2.6282 4.4225 0.3802 1.0461
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1187 GDSC1; GDSC2 -0.5952 17.4617 -8.5953 40.1274
HCC202 GDSC1 1.3247 4.5438 -0.509 10.7139
HCC2157 GDSC1; GDSC2 1.4422 5.2652 -0.7762 9.9801
MDA-MB-436 GDSC1; GDSC2 1.6611 7.5841 -1.7586 15.1165
MDA-MB-415 GDSC1; GDSC2 1.7287 10.2505 -3.0329 21.098
MCF-7 GDSC1; GDSC2 1.8757 5.6878 -0.6602 8.1891
HCC1937 GDSC1; GDSC2 1.8812 4.6736 -0.1644 5.1675
HCC1428 GDSC1; GDSC2 1.925 3.756 0.2953 2.3818
BT-474 GDSC1; GDSC2 1.9495 3.9913 0.2021 2.8672
AU565 GDSC1; GDSC2 1.9676 5.4153 -0.4625 6.7815
MDA-MB-453 GDSC1; GDSC2 2.0309 4.0761 0.2125 2.6663
HCC38 GDSC1; GDSC2 2.0932 4.6252 -0.0027 3.7845
HCC1419 GDSC1 2.2459 11.538 -3.2701 23.7985
DU4475 GDSC1; GDSC2 2.257 3.9579 0.3906 1.3979
Hs 578T GDSC1; GDSC2 2.3188 8.6407 -1.7848 13.5817
CAL-148 GDSC2 2.3311 3.914 0.446 1.0581
CAMA-1 GDSC1; GDSC2 2.3631 6.4238 -0.6773 7.2089
HCC1954 GDSC1; GDSC2 2.3943 4.2712 0.3282 1.5306
MRK-nu-1 GDSC1; GDSC2 2.4455 5.6604 -0.264 4.6417
MFM-223 GDSC1; GDSC2 2.4877 7.5434 -1.1302 9.5676
HDQ-P1 GDSC1; GDSC2 2.5417 5.214 -0.0032 3.0264
MDA-MB-361 GDSC1; GDSC2 2.5566 6.5131 -0.5923 6.3226
EFM-192A GDSC1; GDSC2 2.6145 5.5113 -0.0946 3.4065
HCC1500 GDSC1; GDSC2 2.6294 4.6374 0.2928 1.4253
HCC1395 GDSC1; GDSC2 2.6375 5.8986 -0.2566 4.2616
MDA-MB-175-VII GDSC1; GDSC2 2.7266 10.5041 -2.4012 15.7217
EFM-19 GDSC1; GDSC2 2.7332 7.9933 -1.179 9.3159
CAL-120 GDSC1; GDSC2 2.7852 4.4187 0.4518 0.6469
Evsa-T GDSC1; GDSC2 2.8496 4.738 0.3557 0.9483
UACC-893 GDSC1; GDSC2 3.0097 6.2377 -0.1944 3.3399
MDA-MB-157 GDSC1; GDSC2 3.0529 8.3048 -1.116 8.3156
CAL-51 GDSC1; GDSC2 3.1353 4.8624 0.4296 0.5049
BT-483 GDSC1 3.1674 4.7782 0.4731 0.4645
MDA-MB-231 GDSC1; GDSC2 3.1857 5.2956 0.2863 0.9418
OCUB-M GDSC1; GDSC2 3.2077 4.8335 0.4686 0.3666
HCC1599 GDSC2 3.2259 5.0743 0.3876 0.5785
MDA-MB-330 GDSC1; GDSC2 3.3656 8.6924 -1.099 7.631
HCC70 GDSC1; GDSC2 3.3943 5.2376 0.3947 0.4716
HCC1143 GDSC1; GDSC2 3.5165 6.7315 -0.1397 2.4162
BT-20 GDSC1; GDSC2 3.6498 5.4327 0.4222 0.305
HCC2218 GDSC1; GDSC2 3.6524 5.4297 0.4242 0.3001
CAL-85-1 GDSC1; GDSC2 3.8108 5.7167 0.382 0.3342
HCC1569 GDSC1; GDSC2 3.9226 6.9157 -0.0217 1.5116
YMB-1-E GDSC2 4.3237 6.6128 0.2567 0.4216
HCC1806 GDSC1; GDSC2 4.3383 13.8468 -2.8996 14.5417
COLO 824 GDSC1; GDSC2 4.3649 6.2322 0.4029 0.1611
MDA-MB-468 GDSC1; GDSC2 4.3962 14.2267 -3.0421 15.0286
BT-549 GDSC1; GDSC2 4.6469 15.862 -3.6554 16.9664
T-47D GDSC1; GDSC2 4.9642 14.4352 -2.7712 12.8368
ZR-75-30 GDSC1; GDSC2 5.0356 15.1762 -3.0732 13.9683
JIMT-1 GDSC1; GDSC2 5.5567 15.8939 -3.0787 13.0858
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MOG-G-UVW GDSC1; GDSC2 1.665 4.821 -0.3886 7.0281
CAS-1 GDSC1; GDSC2 1.9627 3.5695 0.4011 1.743
KALS-1 GDSC1; GDSC2 2.1466 6.9267 -1.0707 9.9974
D-392MG GDSC1; GDSC2 2.2604 5.2794 -0.2027 4.6318
PFSK-1 GDSC1; GDSC2 2.3037 6.4986 -0.7533 7.7816
U-87MG ATCC GDSC1; GDSC2 2.357 4.4497 0.2316 2.0602
NMC-G1 GDSC1; GDSC2 2.3771 4.0165 0.4261 1.0977
AM-38 GDSC1; GDSC2 2.4901 4.5985 0.2384 1.8486
DK-MG GDSC1; GDSC2 2.5104 5.1298 0.0166 2.9683
SF295 GDSC1; GDSC2 2.6106 4.0632 0.5135 0.5564
H4 GDSC1; GDSC2 2.6392 4.8754 0.1977 1.8598
U-118MG GDSC1; GDSC2 2.6885 4.75 0.2751 1.4407
Hs 683 GDSC1; GDSC2 2.7619 3.8706 0.6426 0.1519
SF539 GDSC1; GDSC2 2.7927 4.3729 0.4724 0.5734
D283 Med GDSC1; GDSC2 2.8069 4.1547 0.5589 0.3153
SF126 GDSC1; GDSC2 2.8396 4.4777 0.4523 0.609
KINGS-1 GDSC1; GDSC2 2.8614 8.9255 -1.5393 11.0246
8-MG-BA GDSC1; GDSC2 2.9165 4.9438 0.3044 1.0928
YKG-1 GDSC1; GDSC2 2.9388 4.0354 0.649 0.1019
YH-13 GDSC1; GDSC2 2.9451 6.336 -0.2744 3.8593
GI-1 GDSC1; GDSC2 2.9712 7.0776 -0.5954 5.5727
D-263MG GDSC1; GDSC2 3.1153 4.6367 0.5039 0.3199
GaMG GDSC1; GDSC2 3.1371 8.2566 -1.0395 7.7318
U-251MG GDSC1; GDSC2 3.1964 11.6697 -2.6337 15.7339
KNS-42 GDSC1; GDSC2 3.21 4.455 0.6016 0.1139
42-MG-BA GDSC1; GDSC2 3.266 5.207 0.3543 0.6569
Onda 10 GDSC1; GDSC2 3.2994 4.8458 0.4989 0.2642
LN-405 GDSC1; GDSC2 3.3637 4.9998 0.4685 0.3061
D-542MG GDSC1; GDSC2 3.3798 10.2267 -1.8126 11.3714
KNS-81-FD GDSC1; GDSC2 3.3852 5.7317 0.204 1.0909
LN-229 GDSC1; GDSC2 3.4185 9.5152 -1.4502 9.411
SW1088 GDSC1; GDSC2 3.4482 4.9907 0.5028 0.2122
MOG-G-CCM GDSC1; GDSC2 3.4927 5.4078 0.3712 0.4872
D-247MG GDSC1; GDSC2 3.5498 5.6817 0.293 0.6791
DBTRG-05MG GDSC1; GDSC2 3.5523 5.5922 0.3273 0.5777
Becker GDSC1; GDSC2 3.5915 4.9801 0.5568 0.1042
SNB-75 GDSC1; GDSC2 3.6226 5.6436 0.3363 0.5184
M059J GDSC1; GDSC2 3.6394 5.3457 0.4489 0.2561
D-502MG GDSC1; GDSC2 3.6882 7.6444 -0.4398 3.6466
D-566MG GDSC1; GDSC2 3.6914 5.2385 0.5043 0.1529
Daoy GDSC1; GDSC2 3.7702 5.6286 0.3979 0.3149
Onda 11 GDSC1; GDSC2 3.8752 5.9232 0.3329 0.4183
SF268 GDSC1; GDSC2 3.9368 10.6555 -1.655 9.496
D-245MG GDSC2 3.9368 6.7757 0.0396 1.2704
T98G GDSC1; GDSC2 4.1181 5.9348 0.4174 0.1888
SW1783 GDSC1; GDSC2 4.182 6.2774 0.3222 0.3344
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 4.3271 6.561 0.2762 0.3797
D-423MG GDSC1; GDSC2 4.3399 6.8586 0.1748 0.6079
D-336MG GDSC1; GDSC2 4.6193 6.9661 0.2418 0.3558
SK-MG-1 GDSC1; GDSC2 4.8459 15.2566 -3.2344 14.963
A-172 GDSC1; GDSC2 5.0364 29.3043 -9.9452 30.9238
ONS-76 GDSC1; GDSC2 5.0567 16.7118 -3.7866 16.6851
GB-1 GDSC1; GDSC2 5.5066 14.1783 -2.3201 9.9728
LN-18 GDSC1; GDSC2 5.5141 20.0616 -5.0817 20.1224
LNZTA3WT4 GDSC1; GDSC2 6.8826 19.6785 -4.0108 14.425
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 2.7137 8.7116 -1.5379 11.3398
TGBC1TKB GDSC1; GDSC2 3.5372 5.2135 0.4576 0.2704
TGBC24TKB GDSC1; GDSC2 3.5993 5.357 0.4301 0.3056
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC1; GDSC2 2.4848 6.6956 -0.7257 7.2396
MFE-280 GDSC1; GDSC2 2.9319 6.0324 -0.147 3.2059
MFE-296 GDSC1; GDSC2 2.9887 5.6452 0.0506 2.1407
ESS-1 GDSC1; GDSC2 3.0005 4.4623 0.5226 0.3222
MFE-319 GDSC1; GDSC2 3.0223 14.0016 -3.902 21.2712
KLE GDSC1; GDSC2 3.2701 12.0374 -2.7603 16.1396
EN GDSC1; GDSC2 5.1704 13.3552 -2.1452 9.7284
AN3-CA GDSC1; GDSC2 6.339 25.8247 -7.2936 24.2874
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HA7-RCC GDSC1; GDSC2 1.0595 6.2036 -1.5524 15.6657
KTCTL-1M GDSC1; GDSC2 1.1894 7.1282 -1.9077 17.2409
786-O GDSC1; GDSC2 1.2384 4.7101 -0.6604 9.8149
BB65-RCC GDSC1; GDSC2 1.7495 3.4831 0.3137 2.5886
A-498 GDSC1; GDSC2 2.0074 8.0771 -1.7381 14.1016
TK-10 GDSC1; GDSC2 2.1791 4.8605 -0.0584 3.9476
KMRC-1 GDSC1; GDSC2 2.3567 5.0866 -0.0539 3.6063
KTCTL-26A GDSC1; GDSC2 2.4345 9.6588 -2.1998 15.4375
BFTC-909 GDSC1; GDSC2 2.4841 4.4197 0.3113 1.5041
KTCTL-13 GDSC1; GDSC2 2.5559 6.5334 -0.6024 6.3819
KTCTL-195 GDSC1; GDSC2 2.6643 10.4881 -2.4386 16.046
LB1047-RCC GDSC1; GDSC2 2.83 9.9818 -2.0722 13.8722
SW156 GDSC1; GDSC2 2.9131 6.0619 -0.1705 3.3564
SW13 GDSC1; GDSC2 3.0206 4.6304 0.4693 0.4521
VMRC-RCZ GDSC1; GDSC2 3.0833 4.7668 0.4441 0.4909
KMRC-20 GDSC1; GDSC2 3.1211 19.4693 -6.532 28.4391
769-P GDSC1; GDSC2 3.1816 4.9293 0.4235 0.4981
RCC10RGB GDSC1; GDSC2 3.1996 4.3676 0.6273 0.0845
NCC010 GDSC1; GDSC2 3.3218 11.7403 -2.5798 15.2133
ACHN GDSC1; GDSC2 3.3449 5.3671 0.3267 0.6958
Caki-1 GDSC1; GDSC2 3.4961 6.6714 -0.1247 2.3702
VMRC-RCW GDSC1; GDSC2 3.5105 5.2479 0.4356 0.3249
CAL-54 GDSC1; GDSC2 3.5111 5.9769 0.1638 1.1416
NCC021 GDSC1; GDSC2 3.5351 5.4591 0.3692 0.4729
LB996-RCC GDSC2 3.6182 14.1912 -3.5614 18.6895
UO-31 GDSC1; GDSC2 3.6504 5.754 0.3068 0.5849
KTCTL-140 GDSC1; GDSC2 3.6996 11.2377 -2.0816 12.0688
KTCTL-21 GDSC1; GDSC2 3.874 11.6267 -2.1514 12.0623
SN12C GDSC1; GDSC2 3.9044 14.5335 -3.5257 17.95
LB2241-RCC GDSC1; GDSC2 3.994 5.888 0.3893 0.2642
RXF 393L GDSC1; GDSC2 4.1792 6.9123 0.0904 0.9328
OS-RC-2 GDSC1; GDSC2 4.5483 14.3263 -2.9887 14.5157
A-704 GDSC1; GDSC2 5.3582 16.1665 -3.3317 14.4276
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KM12 GDSC1; GDSC2 0.6294 2.72 -0.1855 8.6573
LS180 GDSC1; GDSC2 1.2907 2.8506 0.3043 3.6282
SNU-407 GDSC1; GDSC2 1.7053 4.9177 -0.4067 7.0436
LS411N GDSC1; GDSC2 1.7636 3.3852 0.3677 2.2519
SW948 GDSC1; GDSC2 1.8692 6.675 -1.1497 11.1284
SW837 GDSC1; GDSC2 2.1251 5.2058 -0.2554 5.2057
HCT 116 GDSC1; GDSC2 2.3372 4.4856 0.205 2.2265
SNU-175 GDSC2 2.3421 13.8054 -4.3215 24.3127
SNU-61 GDSC1; GDSC2 2.3903 4.826 0.0838 2.7915
COLO 678 GDSC1; GDSC2 2.437 6.5375 -0.6822 7.0841
HT-29 GDSC1; GDSC2 2.4808 3.8342 0.5458 0.5348
MDST8 GDSC1; GDSC2 2.5252 8.3727 -1.5056 11.5868
COLO205 GDSC1; GDSC2 2.552 3.8979 0.5516 0.4694
SW1116 GDSC1; GDSC2 2.5973 6.1577 -0.4004 5.1438
NCI-H508 GDSC1; GDSC2 2.6266 3.7716 0.6274 0.2256
HCC2998 GDSC1; GDSC2 2.7333 6.4573 -0.4551 5.2081
SW1417 GDSC1; GDSC2 2.7341 4.3843 0.443 0.7139
SW48 GDSC1; GDSC2 2.7474 4.64 0.3481 1.0679
LS513 GDSC1; GDSC2 2.7715 4.7172 0.3282 1.1274
HT115 GDSC1; GDSC2 2.8064 4.1421 0.5633 0.3047
NCI-H716 GDSC1; GDSC2 2.8377 5.044 0.2265 1.4989
DiFi GDSC1; GDSC2 2.8427 7.6832 -0.9589 7.8534
SNU-283 GDSC2 2.9266 4.4355 0.5035 0.4047
CaR-1 GDSC1; GDSC2 3.1054 5.2009 0.2879 0.9985
C2BBe1 GDSC1; GDSC2 3.1308 5.8014 0.0566 1.948
CCK-81 GDSC1; GDSC2 3.1801 5.0929 0.3617 0.6863
LS123 GDSC1; GDSC2 3.1829 4.7413 0.4922 0.3205
LoVo GDSC1; GDSC2 3.1963 5.3408 0.2734 0.9812
GP5d GDSC1; GDSC2 3.2387 4.8422 0.4774 0.3331
HT-55 GDSC1; GDSC2 3.2557 5.2607 0.3298 0.7421
RCM-1 [Human ESC] GDSC1; GDSC2 3.2584 4.7056 0.5329 0.2109
SK-CO-1 GDSC1; GDSC2 3.2983 6.6478 -0.2168 3.0552
T84 GDSC1; GDSC2 3.4072 5.7114 0.2216 1.0099
SW626 GDSC1; GDSC2 3.4406 6.2523 0.0214 1.7771
SNU-C1 GDSC1; GDSC2 3.4953 5.1237 0.4736 0.2522
SW1463 GDSC1; GDSC2 3.5006 5.0032 0.5172 0.175
SNU-81 GDSC1; GDSC2 3.5025 5.2743 0.4232 0.3554
LS1034 GDSC1; GDSC2 3.5434 5.1327 0.488 0.2125
CL-11 GDSC1; GDSC2 3.6457 5.4057 0.4302 0.2903
RKO GDSC1; GDSC2 3.7298 5.3716 0.4725 0.1918
HCT 15 GDSC1; GDSC2 3.9068 5.3385 0.5446 0.0751
CW-2 GDSC1; GDSC2 3.9263 6.1191 0.282 0.5199
COLO 320HSR GDSC1; GDSC2 3.9913 6.003 0.3481 0.3436
NCI-H747 GDSC1; GDSC2 4.0742 6.1276 0.335 0.3431
SNU-C5 GDSC1; GDSC2 4.1141 14.7054 -3.4631 17.2791
SNU-C2B GDSC1; GDSC2 4.3463 12.2998 -2.1641 11.2307
SW620 GDSC1; GDSC2 6.6709 16.7174 -2.7871 10.1821
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 2.274 3.9297 0.4112 1.28
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-7 GDSC1; GDSC2 1.8602 8.9802 -2.2978 17.3775
JHH-4 GDSC1; GDSC2 1.9772 9.5693 -2.5 18.0456
JHH-6 GDSC1; GDSC2 1.9956 3.0052 0.6559 0.5
JHH-1 GDSC1; GDSC2 2.3213 5.2892 -0.1689 4.3229
Hep 3B2.1-7 GDSC1; GDSC2 2.583 4.5948 0.2875 1.5012
Hep-G2/C3A GDSC1; GDSC2 2.8032 4.1432 0.5616 0.3101
HLE GDSC1; GDSC2 2.8539 5.1703 0.1821 1.6816
Huh-7 GDSC1; GDSC2 2.9388 9.2927 -1.663 11.5184
SNU-449 GDSC1; GDSC2 3.069 6.0835 -0.095 2.7508
SK-HEP-1 GDSC1; GDSC2 3.1553 4.5978 0.5328 0.2426
JHH-2 GDSC1; GDSC2 3.8376 5.6448 0.4169 0.258
SNU-398 GDSC1; GDSC2 4.2523 16.1989 -4.0893 19.3063
HuH-1 GDSC1; GDSC2 4.5532 14.3371 -2.9906 14.5143
SNU-387 GDSC1; GDSC2 4.8086 15.2493 -3.2554 15.1158
SNU-423 GDSC1; GDSC2 7.1209 19.6534 -3.8538 13.5213
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 186 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2369 GDSC1; GDSC2 0.3557 19.4515 -8.768 38.0794
NCI-H2803 GDSC1; GDSC2 0.3606 5.9852 -2.0436 20.5502
COR-L105 GDSC1; GDSC2 0.4313 18.6937 -8.3251 37.3783
NCI-H1341 GDSC1; GDSC2 0.9822 3.6169 -0.3233 8.4271
NCI-H847 GDSC1 1.0603 3.1962 -0.0483 8.0484
NCI-H226 GDSC1; GDSC2 1.1972 2.4937 0.4104 3.1973
NCI-H1703 GDSC1; GDSC2 1.4442 26.2303 -11.2469 38.378
NCI-H82 GDSC1; GDSC2 1.4873 8.1311 -2.168 17.744
Lu-135 GDSC1; GDSC2 1.6354 3.4407 0.2599 3.1284
A-549 GDSC1; GDSC2 1.7412 3.6678 0.2217 3.1434
NCI-H2122 GDSC1; GDSC2 1.779 9.7944 -2.766 19.7976
NCI-H2795 GDSC1; GDSC2 1.8042 5.4998 -0.62 8.1142
NCI-H1623 GDSC1; GDSC2 1.8123 4.7756 -0.2612 5.9052
CAL-12T GDSC1; GDSC2 1.8183 3.5646 0.3185 2.4358
NCI-H596 GDSC1; GDSC2 1.858 4.5859 -0.1381 5.0578
NCI-H2030 GDSC1; GDSC2 1.8992 5.1049 -0.36 6.3126
NCI-H2444 GDSC1; GDSC2 2.0229 3.4788 0.4735 1.2873
IA-LM GDSC1; GDSC2 2.0379 4.8322 -0.1355 4.6703
NCI-H211 GDSC1; GDSC2 2.0432 3.9153 0.2926 2.2032
NCI-H196 GDSC1; GDSC2 2.0468 9.0119 -2.1705 16.2577
LK-2 GDSC1; GDSC2 2.0563 4.4419 0.0595 3.4929
NCI-H2818 GDSC1; GDSC2 2.0829 17.8245 -6.5277 30.6672
NCI-H1755 GDSC1; GDSC2 2.1419 4.3439 0.1566 2.792
NCI-H345 GDSC1; GDSC2 2.1692 3.3253 0.6076 0.5432
SBC-5 GDSC1; GDSC2 2.2153 3.4655 0.5729 0.6376
NCI-H1048 GDSC1; GDSC2 2.2358 4.688 0.0557 3.1973
NCI-H1693 GDSC1; GDSC2 2.2996 7.6555 -1.3167 11.054
HCC827 GDSC1; GDSC2 2.3346 4.8771 0.0284 3.1844
NCI-H1435 GDSC1; GDSC2 2.3479 4.1969 0.3359 1.5503
NCI-H1155 GDSC1; GDSC2 2.3504 4.7582 0.0913 2.8134
BEN GDSC1; GDSC2 2.3683 3.7627 0.5244 0.6976
COLO 668 GDSC1; GDSC2 2.3693 4.6407 0.1544 2.446
NCI-H1915 GDSC1; GDSC2 2.3997 5.4125 -0.1776 4.2307
UMC-11 GDSC1; GDSC2 2.4048 4.3681 0.2924 1.6913
NCI-H290 GDSC1; GDSC2 2.4218 7.117 -0.97 8.7912
SW1573 GDSC1; GDSC2 2.4451 6.0832 -0.4618 5.7838
NCI-H2810 GDSC1; GDSC2 2.449 4.7453 0.1525 2.34
Lu-99A GDSC1; GDSC2 2.4514 4.6485 0.1961 2.1117
NCI-H292 GDSC1; GDSC2 2.4647 5.2082 -0.0451 3.3767
NCI-H661 GDSC1; GDSC2 2.4918 6.7782 -0.7604 7.4267
NCI-H513 GDSC1; GDSC2 2.4947 11.6731 -3.1479 19.6096
NCI-H2029 GDSC1; GDSC2 2.5035 3.9394 0.5151 0.6263
SK-LU-1 GDSC1; GDSC2 2.5096 8.7221 -1.6867 12.6059
NCI-H1581 GDSC1; GDSC2 2.5246 3.9011 0.5389 0.5286
NCI-H1869 GDSC1 2.5267 6.231 -0.479 7.0816
PaCa-3 GDSC1; GDSC2 2.5271 5.2138 -0.0114 3.0931
PC-14 GDSC1; GDSC2 2.529 4.6907 0.2192 1.8931
NCI-H524 GDSC1; GDSC2 2.5357 4.5215 0.2945 1.5227
NCI-H1437 GDSC1; GDSC2 2.5933 6.2995 -0.4689 5.5422
NCI-H838 GDSC1; GDSC2 2.5977 11.7442 -3.1056 19.183
COR-L95 GDSC1; GDSC2 2.609 9.303 -1.8989 13.4946
LB647-SCLC GDSC1; GDSC2 2.6105 10.3616 -2.4158 16.0653
NCI-H2347 GDSC1; GDSC2 2.6192 5.9946 -0.3116 4.6016
COR-L88 GDSC1; GDSC2 2.6389 4.1597 0.4885 0.6221
NCI-H1876 GDSC1; GDSC2 2.6489 4.1958 0.479 0.6484
SBC-3 GDSC1; GDSC2 2.6651 8.2471 -1.3473 10.4007
NCI-H1793 GDSC1; GDSC2 2.6652 12.838 -3.595 20.973
NCI-H1975 GDSC1; GDSC2 2.668 11.921 -3.1404 19.159
NCI-H2081 GDSC1; GDSC2 2.6737 5.0998 0.1196 2.1999
KNS-62 GDSC1; GDSC2 2.7032 10.3261 -2.331 15.4395
NCI-H727 GDSC1; GDSC2 2.708 4.9255 0.2116 1.711
NCI-H720 GDSC1 2.711 3.9337 0.6016 0.3142
NCI-H2110 GDSC1; GDSC2 2.7135 7.6091 -1.0088 8.3963
NCI-H1105 GDSC1; GDSC2 2.7138 4.2387 0.4902 0.5657
COR-L311 GDSC2 2.7237 4.6698 0.325 1.1866
NCI-H2066 GDSC1; GDSC2 2.7347 11.1436 -2.7088 17.1296
Calu-3 GDSC1; GDSC2 2.7487 4.699 0.3249 1.1628
NCI-H1792 GDSC1; GDSC2 2.7596 4.9083 0.2444 1.5022
NCI-H1694 GDSC1; GDSC2 2.7689 4.4543 0.431 0.7312
NCI-H1436 GDSC1; GDSC2 2.7721 4.2333 0.5163 0.4492
NCI-H1666 GDSC1; GDSC2 2.7789 11.067 -2.6389 16.7084
NCI-H1734 GDSC1; GDSC2 2.7856 6.1587 -0.287 4.182
NCI-H526 GDSC1; GDSC2 2.8023 4.2576 0.5195 0.4236
NCI-H2405 GDSC1; GDSC2 2.8029 7.5018 -0.8991 7.5944
NCI-H1944 GDSC1; GDSC2 2.8364 14.7033 -4.3879 23.3563
NCI-H1963 GDSC1; GDSC2 2.8415 4.8377 0.3123 1.1283
NCI-H2171 GDSC2 2.8555 4.2793 0.5326 0.3609
LCLC-103H GDSC1; GDSC2 2.8582 4.3731 0.4992 0.4522
Lu-65 GDSC1; GDSC2 2.8622 4.3594 0.5059 0.4308
NCI-H2731 GDSC1; GDSC2 2.8632 4.7393 0.3613 0.9159
COR-L279 GDSC1; GDSC2 2.8728 4.3026 0.5309 0.3572
NCI-H522 GDSC2 2.9044 5.0726 0.2469 1.3422
Lu-165 GDSC1; GDSC2 2.9142 4.6867 0.4041 0.7215
NCI-H810 GDSC1; GDSC2 2.9163 4.2895 0.5524 0.2857
RERF-LC-KJ GDSC1; GDSC2 2.9231 21.3402 -7.6152 30.9684
NCI-H1568 GDSC1; GDSC2 2.9335 12.0763 -3.0211 18.0325
ABC-1 GDSC1; GDSC2 2.9458 12.3978 -3.1699 18.6276
Lu-134-A GDSC1; GDSC2 2.9488 6.0183 -0.1315 3.101
EBC-1 GDSC1; GDSC2 2.9529 9.1759 -1.5972 11.1388
ChaGo-K-1 GDSC1; GDSC2 2.9882 5.0574 0.2919 1.0802
NCI-H64 GDSC1; GDSC2 2.9959 4.581 0.4776 0.4414
NCI-H187 GDSC1 3.0314 4.2265 0.6165 0.1604
NCI-H2141 GDSC1; GDSC2 3.0361 4.7984 0.413 0.6117
A-427 GDSC1; GDSC2 3.0428 8.2097 -1.0778 8.1242
NCI-H460 GDSC1; GDSC2 3.052 17.6753 -5.6954 26.6242
NCI-H1688 GDSC1; GDSC2 3.0562 4.5538 0.5111 0.3269
NCI-H2227 GDSC1; GDSC2 3.0578 5.1351 0.2925 1.0195
LC-1/sq GDSC1; GDSC2 3.0615 7.3401 -0.6612 5.7793
SHP-77 GDSC1; GDSC2 3.0726 4.4053 0.5697 0.1965
NCI-H1304 GDSC1 3.0734 4.6138 0.4961 0.4438
COR-L32 GDSC2 3.0769 5.2778 0.2446 1.1906
Ms-1 GDSC1; GDSC2 3.092 4.6335 0.4962 0.3481
EKVX GDSC1; GDSC2 3.1047 6.6111 -0.3064 3.7871
NCI-H2172 GDSC1; GDSC2 3.1072 4.4399 0.5702 0.1858
NCI-H1563 GDSC1; GDSC2 3.1083 16.7493 -5.194 25.1704
NCI-H2869 GDSC1; GDSC2 3.1193 7.819 -0.8468 6.7014
COR-L23 GDSC1; GDSC2 3.123 4.6494 0.5023 0.3207
SW1271 GDSC1; GDSC2 3.186 8.5872 -1.1633 8.317
NCI-H1573 GDSC1; GDSC2 3.1912 5.8324 0.0734 1.8059
NCI-H1651 GDSC1; GDSC2 3.204 5.2886 0.297 0.8899
NCI-H650 GDSC1; GDSC2 3.2064 4.9679 0.4191 0.4975
DMS 273 GDSC1; GDSC2 3.2116 5.1109 0.368 0.6469
NCI-H2291 GDSC1; GDSC2 3.2176 5.0737 0.3844 0.5928
NCI-H1770 GDSC1; GDSC2 3.225 4.4407 0.6116 0.0986
NCI-H23 GDSC1; GDSC2 3.233 15.2563 -4.3636 22.3809
NCI-H841 GDSC1; GDSC2 3.2432 7.0194 -0.4097 4.1231
NCI-H69 GDSC1; GDSC2 3.2518 4.8484 0.4801 0.3217
NCI-H2135 GDSC1; GDSC2 3.2988 4.6953 0.551 0.1691
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2 3.3006 10.0723 -1.7917 11.427
IST-SL2 GDSC1; GDSC2 3.3123 6.0399 0.0467 1.7972
NCI-H748 GDSC2 3.3228 5.5457 0.2491 0.9737
NCI-H2170 GDSC1; GDSC2 3.3601 15.8412 -4.5573 22.7265
NCI-H835 GDSC1; GDSC2 3.366 5.6915 0.2113 1.0789
RERF-LC-MS GDSC1; GDSC2 3.3887 5.0832 0.4482 0.3419
NCI-H1648 GDSC1; GDSC2 3.3891 6.7791 -0.2253 2.9792
NCI-H250 GDSC2 3.404 5.1206 0.4407 0.3533
NCI-H1355 GDSC1; GDSC2 3.4047 8.5426 -1.0055 7.0559
HCC366 GDSC1; GDSC2 3.4155 9.6499 -1.5156 9.7612
SBC-1 GDSC1; GDSC2 3.4188 4.8665 0.535 0.1662
NCI-H510A GDSC1; GDSC2 3.4195 5.2546 0.3984 0.4502
NCI-H2342 GDSC1; GDSC2 3.4384 6.3987 -0.0399 2.0482
HCC15 GDSC1; GDSC2 3.4425 10.8888 -2.0868 12.6167
NCI-H1299 GDSC1; GDSC2 3.4441 6.0567 0.102 1.4371
NCI-H1092 GDSC1; GDSC2 3.4463 4.9376 0.5204 0.1828
Calu-6 GDSC1; GDSC2 3.489 5.4846 0.3416 0.5701
NCI-H520 GDSC1; GDSC2 3.508 6.9539 -0.238 2.891
IST-SL1 GDSC1; GDSC2 3.51 5.3032 0.4157 0.3696
NCI-H2085 GDSC1; GDSC2 3.5368 9.7446 -1.4822 9.3523
COR-L321 GDSC1; GDSC2 3.5382 5.5823 0.3252 0.5908
NCI-H1836 GDSC1; GDSC2 3.5388 4.8154 0.5936 0.0733
NCI-H2196 GDSC2 3.565 5.6495 0.3112 0.617
NCI-H358 GDSC1; GDSC2 3.5657 9.835 -1.5061 9.4225
LCLC-97TM1 GDSC1; GDSC2 3.5766 5.3658 0.4185 0.3382
LC-2/ad GDSC1; GDSC2 3.5893 5.7173 0.2958 0.6486
HCC33 GDSC2 3.6158 5.1475 0.5087 0.1622
NCI-H146 GDSC1; GDSC2 3.6279 5.2768 0.4686 0.2236
NCI-H2023 GDSC1; GDSC2 3.6361 6.3277 0.0817 1.3517
DMS 79 GDSC1; GDSC2 3.6367 5.1214 0.5248 0.1356
SK-MES-1 GDSC1; GDSC2 3.6412 5.5859 0.3644 0.4383
NCI-H2722 GDSC1; GDSC2 3.6614 32.8994 -12.7896 36.17
COR-L303 GDSC2 3.6703 5.0661 0.555 0.0945
NCI-H3255 GDSC1; GDSC2 3.6719 5.5835 0.377 0.3958
NCI-H2087 GDSC1; GDSC2 3.6936 5.7562 0.3231 0.5198
NCI-H209 GDSC1; GDSC2 3.7316 5.9468 0.2682 0.6521
EMC-BAC-1 GDSC1; GDSC2 3.7412 7.1623 -0.2076 2.4746
HCC44 GDSC1; GDSC2 3.7604 6.9881 -0.1263 2.0926
Lu-139 GDSC1; GDSC2 3.7641 5.4301 0.4646 0.1961
CPC-N GDSC1; GDSC2 3.775 5.8591 0.3174 0.4972
NCI-H441 GDSC1; GDSC2 3.7772 5.6733 0.3848 0.3398
HOP-92 GDSC1; GDSC2 3.7898 12.388 -2.5703 14.1853
EPLC-272H GDSC1; GDSC2 3.8301 13.2182 -2.9417 15.7353
NCI-H1993 GDSC1; GDSC2 3.8958 5.9306 0.338 0.3988
NCI-H446 GDSC1; GDSC2 3.9332 5.4499 0.5166 0.0982
NCI-H740 GDSC2 3.9781 6.4354 0.1864 0.7567
NCI-H3122 GDSC1; GDSC2 3.9789 5.881 0.3862 0.2739
NCI-H2591 GDSC1; GDSC2 3.9804 12.9365 -2.7043 14.3996
NCI-H1650 GDSC1; GDSC2 4.2298 6.1163 0.395 0.1979
NCI-H2595 GDSC1; GDSC2 4.2326 12.9238 -2.531 13.1326
NCI-H647 GDSC1; GDSC2 4.2481 6.2019 0.3722 0.2283
HCC78 GDSC1; GDSC2 4.2607 6.1178 0.4053 0.1772
NCI-H2804 GDSC1; GDSC2 4.4011 6.6585 0.2693 0.3696
LXF 289 GDSC1; GDSC2 4.4553 12.2222 -2.0595 10.5412
NCI-H1838 GDSC1; GDSC2 4.5038 11.6922 -1.7851 9.1432
NCI-H322M GDSC1; GDSC2 4.6433 6.5208 0.4017 0.1198
DMS 53 GDSC1; GDSC2 4.6819 19.5256 -5.4025 22.5594
NCI-H2373 GDSC1; GDSC2 4.7415 19.2263 -5.2146 21.9164
NCI-H2009 GDSC1; GDSC2 4.8137 14.3823 -2.8425 13.4095
NCI-H2228 GDSC1; GDSC2 5.2672 17.853 -4.1904 17.7289
DMS 114 GDSC1; GDSC2 5.7361 14.8725 -2.4996 10.3905
HOP-62 GDSC1; GDSC2 5.7927 17.5401 -3.6986 15.0677
VMRC-LCD GDSC1; GDSC2 6.323 16.5487 -2.9138 11.2004
NCI-H1781 GDSC1; GDSC2 6.441 25.8494 -7.2343 24.0004
RERF-LC-Sq1 GDSC1; GDSC2 6.6733 18.7877 -3.7281 13.7529
EMC-BAC-2 GDSC1; GDSC2 6.6835 23.5036 -5.9403 20.5524
LOU-NH91 GDSC1; GDSC2 6.7467 19.1094 -3.8315 14.0079
NCI-H2461 GDSC1; GDSC2 6.7765 18.7654 -3.6549 13.3312
⏷ Show the Full List of 186 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 4.5073 6.2529 0.4445 0.0959
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OE19 GDSC1; GDSC2 1.8491 3.311 0.4519 1.6436
TE-9 GDSC1; GDSC2 2.3447 9.0978 -1.9902 14.5951
OE21 GDSC1; GDSC2 2.4714 7.6784 -1.2067 10.0394
TE-6 GDSC1; GDSC2 2.4814 8.8867 -1.7873 13.2078
OE33 GDSC1; GDSC2 2.5017 6.173 -0.4677 5.7087
KYSE-70 GDSC1; GDSC2 2.5562 4.9548 0.1194 2.3597
T.T GDSC1; GDSC2 2.8346 4.7551 0.3422 1.0142
EC-GI-10 GDSC1; GDSC2 2.8667 4.8251 0.329 1.0387
KYSE-410 GDSC1; GDSC2 2.9457 11.0459 -2.5082 15.7199
TE-11 GDSC1; GDSC2 3.109 4.9196 0.3975 0.6161
TE-5 GDSC1; GDSC2 3.1116 5.4104 0.2075 1.3099
KYSE-510 GDSC1; GDSC2 3.1778 5.3728 0.2527 1.0735
KYSE-150 GDSC1; GDSC2 3.2678 4.8544 0.4841 0.3068
COLO 680N GDSC1; GDSC2 3.3194 5.0608 0.4297 0.4152
KYSE-270 GDSC1; GDSC2 3.3685 5.116 0.4288 0.3962
KYSE-520 GDSC1; GDSC2 3.3896 14.5589 -3.9057 20.4626
TE-4 GDSC1; GDSC2 3.4929 12.5919 -2.8728 16.1486
TE-8 GDSC1; GDSC2 3.5753 5.8426 0.2431 0.8202
TE-1 GDSC1; GDSC2 3.5934 10.9634 -2.0215 11.987
KYSE-140 GDSC1; GDSC2 3.8991 16.1299 -4.306 20.7643
TE-10 GDSC1; GDSC2 3.9454 5.7004 0.4364 0.1982
TE-15 GDSC1; GDSC2 3.9591 6.0354 0.3246 0.4052
KYSE-180 GDSC1; GDSC2 5.848 21.752 -5.6665 21.1967
KYSE-450 GDSC1; GDSC2 7.251 17.9275 -2.9967 10.1913
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Caov-4 GDSC1; GDSC2 1.4078 11.8487 -4.0883 25.9576
OAW42 GDSC1; GDSC2 2.005 5.2267 -0.3458 5.9959
OVCAR-5 GDSC1; GDSC2 2.0824 10.1812 -2.7227 18.8028
TOV-112D GDSC1; GDSC2 2.1413 4.7988 -0.0534 3.9888
TOV-21G GDSC1; GDSC2 2.2948 3.8675 0.4475 1.0896
OAW28 GDSC1; GDSC2 2.4326 5.4597 -0.1792 4.1813
OC 314 GDSC1; GDSC2 2.4353 7.003 -0.906 8.391
RMG-I GDSC1; GDSC2 2.5774 7.5413 -1.0677 9.0172
EFO-27 GDSC1; GDSC2 2.7152 4.6483 0.3297 1.1749
TYK-nu GDSC1; GDSC2 2.7311 5.2309 0.0935 2.2547
OVISE GDSC1; GDSC2 2.8011 4.1873 0.5448 0.3543
JHOS-2 GDSC1; GDSC2 2.8866 4.8135 0.3426 0.9683
FU-OV-1 GDSC1; GDSC2 2.9787 5.007 0.3076 1.027
OVCAR-3 GDSC1; GDSC2 3.0555 4.9982 0.345 0.8278
JHOS-4 GDSC1; GDSC2 3.0709 19.6704 -6.6705 28.8392
Caov-3 GDSC2 3.1333 4.9115 0.4106 0.5619
A2780 GDSC1; GDSC2 3.1757 5.1083 0.354 0.7143
DOV13 GDSC1; GDSC2 3.2255 6.0542 -0.0018 2.1102
Kuramochi GDSC1; GDSC2 3.2397 7.298 -0.5363 4.8012
OVK18 GDSC1; GDSC2 3.3016 5.9353 0.0844 1.6448
OVCAR-8 GDSC1; GDSC2 3.4083 4.9615 0.4984 0.2313
SK-OV-3 GDSC1; GDSC2 3.5031 9.6841 -1.4753 9.3807
OV56 GDSC1; GDSC2 3.8154 9.6378 -1.2591 7.6806
EFO-21 GDSC1; GDSC2 3.9485 5.4319 0.5278 0.0854
OVCAR-4 GDSC1; GDSC2 5.4553 14.145 -2.3353 10.121
OVKATE GDSC1; GDSC2 5.5652 21.491 -5.7355 21.8675
OVTOKO GDSC1; GDSC2 5.6253 15.0398 -2.6423 11.1725
ES-2 GDSC1; GDSC2 5.8833 16.4032 -3.1124 12.6808
OV-90 GDSC1; GDSC2 7.1531 16.7049 -2.5114 8.4262
IGROV-1 GDSC1; GDSC2 8.3404 26.353 -6.2058 18.7697
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Panc 10.05 GDSC1; GDSC2 1.9187 4.4322 -0.0241 4.2485
SU.86.86 GDSC1; GDSC2 1.9574 4.187 0.1162 3.3479
Capan-1 GDSC1; GDSC2 2.077 10.8094 -3.0386 20.201
PSN1 GDSC1; GDSC2 2.1318 4.4646 0.0954 3.1523
KP-4 GDSC1; GDSC2 2.4674 3.9405 0.4987 0.7146
KP-3 GDSC1; GDSC2 2.5464 6.8586 -0.7625 7.327
PaTu 8902 GDSC1; GDSC2 2.5489 4.0202 0.5035 0.6341
HuP-T4 GDSC1; GDSC2 2.6393 6.2154 -0.4012 5.0719
CFPAC-1 GDSC1; GDSC2 2.7074 8.8081 -1.5889 11.6299
SW1990 GDSC1; GDSC2 2.7348 4.8808 0.2437 1.5328
KP-2 GDSC1; GDSC2 2.7506 4.3235 0.4734 0.5974
YAPC GDSC1; GDSC2 2.7923 4.0012 0.6081 0.2085
QGP-1 GDSC1; GDSC2 2.8609 4.4301 0.4791 0.5106
PL4 GDSC1; GDSC2 2.886 5.2494 0.1651 1.724
DAN-G GDSC1; GDSC2 2.8891 8.0749 -1.1141 8.6309
MIA PaCa-2 GDSC1; GDSC2 2.9385 5.4226 0.1189 1.8779
Panc 02.03 GDSC1; GDSC2 3.0747 4.8478 0.4104 0.5966
Hs 766T GDSC1; GDSC2 3.3795 7.5316 -0.5606 4.7109
Panc 04.03 GDSC1; GDSC2 3.4262 5.2515 0.4021 0.4376
SUIT-2 GDSC1; GDSC2 3.435 5.0749 0.4685 0.2815
KP-1N GDSC1; GDSC2 3.4501 5.4607 0.3348 0.6103
HPAC GDSC1; GDSC2 3.4881 5.4411 0.3572 0.527
MZ-PC-1 GDSC1; GDSC2 3.5162 5.7774 0.243 0.859
Panc 03.27 GDSC1; GDSC2 3.7227 5.435 0.4481 0.2341
PaTu 8988t GDSC1; GDSC2 3.7367 11.6521 -2.2542 12.8255
HPAF-II GDSC1; GDSC2 3.8174 5.6054 0.4233 0.2522
BxPC-3 GDSC1; GDSC2 3.8664 5.9588 0.3167 0.4598
Panc 08.13 GDSC1; GDSC2 3.9155 19.724 -6.0572 25.7434
Capan-2 GDSC1; GDSC2 3.9753 6.055 0.3238 0.401
AsPC-1 GDSC1; GDSC2 3.9944 6.4133 0.2013 0.7047
HuP-T3 GDSC1; GDSC2 6.1544 20.1467 -4.6937 17.8415
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1; GDSC2 1.8586 4.5437 -0.1174 4.9317
NCI-H28 GDSC1; GDSC2 2.6406 4.6861 0.278 1.48
MSTO-211H GDSC1; GDSC2 3.2395 5.1668 0.3585 0.6596
IST-Mes1 GDSC1; GDSC2 3.3757 4.8524 0.5244 0.1939
NCI-H2452 GDSC1; GDSC2 3.7594 5.8898 0.3002 0.5493
NCI-H2052 GDSC1; GDSC2 6.6535 17.3611 -3.0874 11.3896
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 GDSC1; GDSC2 1.8571 7.3466 -1.4904 13.1177
NCI-H660 GDSC2 2.7336 4.0318 0.575 0.3072
VCaP GDSC1; GDSC2 3.1565 4.4683 0.5782 0.1596
LNCaP clone FGC GDSC1; GDSC2 3.4335 13.0169 -3.1209 17.3305
22Rv1 GDSC1; GDSC2 3.5566 12.7 -2.8807 16.0467
PC-3 GDSC1; GDSC2 4.177 6.2573 0.3274 0.3258
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 3.7422 16.3038 -4.5043 21.7415
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-28 GDSC1; GDSC2 1.5034 3.1431 0.3135 3.0828
UACC-257 GDSC1; GDSC2 1.7184 10.3136 -3.0725 21.293
G-mel GDSC1; GDSC2 1.7755 9.4887 -2.6166 19.1263
A101D GDSC1; GDSC2 1.7949 4.4742 -0.1276 5.1307
IGR-1 GDSC1; GDSC2 1.9403 3.7643 0.3006 2.3265
SK-MEL-2 GDSC1; GDSC2 2.0069 4.7657 -0.1243 4.6664
IGR-37 GDSC1; GDSC2 2.0378 3.9929 0.2545 2.4212
A2058 GDSC1; GDSC2 2.1652 3.1738 0.664 0.3503
COLO 783 GDSC1; GDSC2 2.2171 4.6093 0.0805 3.0904
451Lu GDSC1; GDSC2 2.2198 5.8052 -0.4778 6.3308
GAK GDSC1; GDSC2 2.2457 3.5395 0.5573 0.6728
VMRC-MELG GDSC1; GDSC2 2.2866 3.8813 0.4377 1.1429
RPMI-7951 GDSC1; GDSC2 2.298 7.7327 -1.3555 11.2768
SK-MEL-1 GDSC1; GDSC2 2.3234 3.9081 0.4447 1.0718
HT-144 GDSC1; GDSC2 2.3653 7.1426 -1.0213 9.2123
MZ-MEL-2 GDSC1; GDSC2 2.4044 6.7448 -0.803 7.8577
MeWo GDSC1; GDSC2 2.4086 4.2151 0.3592 1.3674
WM35 GDSC1; GDSC2 2.4087 4.9778 0.0262 3.0759
Hs 938.T GDSC1; GDSC2 2.4128 10.7273 -2.7423 18.0574
CP66-MEL GDSC1; GDSC2 2.4416 6.8413 -0.8242 7.9025
MMAc-SF GDSC1; GDSC2 2.4521 4.2434 0.369 1.2736
Hs 940.T GDSC1; GDSC2 2.5202 5.0012 0.0792 2.62
SH-4 GDSC1; GDSC2 2.5334 4.5857 0.2663 1.6592
RVH-421 GDSC1; GDSC2 2.5355 4.2754 0.3961 1.0679
COLO 800 GDSC1; GDSC2 2.6331 4.1518 0.4891 0.6242
SK-MEL-30 GDSC1; GDSC2 2.6338 4.0899 0.513 0.5425
HMV-II GDSC1; GDSC2 2.6352 8.6651 -1.5702 11.69
MZ-MEL-7 GDSC1; GDSC2 2.6363 5.6303 -0.1355 3.5945
IPC-298 GDSC1; GDSC2 2.6955 3.8574 0.6229 0.2107
WM1552C GDSC1; GDSC2 2.7596 4.3767 0.4569 0.6471
COLO 792 GDSC1; GDSC2 2.7696 6.0473 -0.246 3.9834
A-388 GDSC1; GDSC2 2.8427 5.5801 0.002 2.5654
CHL-1 GDSC1; GDSC2 2.8548 5.4336 0.0715 2.2047
SK-MEL-3 GDSC1; GDSC2 2.8593 4.564 0.4277 0.6783
WM278 GDSC1; GDSC2 2.9004 4.9548 0.2926 1.1551
LOX-IMVI GDSC1; GDSC2 2.9525 4.6812 0.4224 0.6339
UACC-62 GDSC1; GDSC2 2.9526 4.1557 0.6128 0.1532
WM115 GDSC1; GDSC2 2.997 4.2289 0.6035 0.1575
Mel Ho GDSC1; GDSC2 3.0004 4.2945 0.582 0.1947
CP50-MEL-B GDSC1; GDSC2 3.0157 4.4989 0.5153 0.3336
WT2-iPS GDSC1; GDSC2 3.0172 7.0104 -0.5369 5.1701
A-375 GDSC1; GDSC2 3.0314 4.8744 0.3822 0.7157
LB2518-MEL GDSC1; GDSC2 3.1476 4.5695 0.5398 0.231
M14 GDSC1 3.1526 4.7051 0.4937 0.41
SK-MEL-24 GDSC1; GDSC2 3.1527 10.8204 -2.2525 14.042
WM793 GDSC1; GDSC2 3.2427 4.9347 0.4456 0.4089
SK-MEL-31 GDSC1; GDSC2 3.2481 11.5809 -2.5542 15.2568
LB373-MEL-D GDSC1; GDSC2 3.3194 10.8187 -2.1367 13.1195
COLO 679 GDSC1; GDSC2 3.4141 4.8087 0.553 0.1404
SK-MEL-5 GDSC1; GDSC2 3.5077 10.4724 -1.8447 11.2762
A-431 GDSC1; GDSC2 3.563 5.217 0.4658 0.2469
COLO 829 GDSC1; GDSC2 3.5904 5.6315 0.328 0.5564
DJM-1 GDSC1; GDSC2 3.9857 5.7346 0.439 0.1855
IST-MEL1 GDSC1; GDSC2 4.103 5.9646 0.4019 0.2155
G-361 GDSC1; GDSC2 7.1899 22.2629 -5.0218 17.198
Mel JuSo GDSC1; GDSC2 8.2535 22.7864 -4.6061 14.3868
EquiPSC Line K2 GDSC1; GDSC2 3.1499 13.3043 -3.4654 19.3478
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 3.9796 13.0812 -2.7742 14.708
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYM-1 GDSC1; GDSC2 1.7885 10.5747 -3.1472 21.4158
SK-LMS-1 GDSC1; GDSC2 2.1352 7.0854 -1.1563 10.5217
Rh18 GDSC1 2.2017 3.7036 0.4697 1.359
G-402 GDSC1; GDSC2 2.5414 6.5288 -0.6095 6.4519
VA-ES-BJ GDSC1; GDSC2 2.5725 9.3158 -1.9314 13.7479
SW982 GDSC1; GDSC2 2.6065 3.7564 0.6253 0.2383
SW684 GDSC1; GDSC2 2.6129 3.8495 0.5941 0.3128
Rh41 GDSC1; GDSC2 2.6175 4.6295 0.2902 1.4502
SW872 GDSC1; GDSC2 2.7441 11.4231 -2.8391 17.6885
STS-0421 GDSC1; GDSC2 2.8995 6.5915 -0.4162 4.7042
TE 441.T GDSC2 2.9815 4.3806 0.5446 0.2783
HT-1080 GDSC1; GDSC2 3.0492 4.613 0.487 0.3903
RKN GDSC1; GDSC2 3.2159 4.7061 0.5171 0.2546
EW-8 GDSC1; GDSC2 3.2171 13.6168 -3.5696 19.5991
GCT GDSC1; GDSC2 3.2327 4.9115 0.4501 0.4019
MES-SA GDSC1; GDSC2 3.5778 9.3132 -1.2551 8.0803
MFH-ino GDSC1; GDSC2 3.9414 14.7437 -3.6017 18.1641
A-204 GDSC1; GDSC2 3.9857 11.8052 -2.163 11.9012
G-401 GDSC1; GDSC2 4.2946 6.3217 0.3477 0.2567
SK-UT-1 GDSC1; GDSC2 4.4915 12.7044 -2.2614 11.4203
Rh30 GDSC1; GDSC2 5.2722 21.0695 -5.7358 22.3833
Hs 633.T GDSC1; GDSC2 5.5761 14.3086 -2.3382 9.943
RD GDSC1; GDSC2 6.908 21.0303 -4.6238 16.4095
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC1; GDSC2 1.6744 7.0254 -1.4708 13.482
KATO III GDSC1; GDSC2 1.6912 3.3604 0.3341 2.5795
HSC-39 GDSC1; GDSC2 1.7566 6.5004 -1.1479 11.4014
MKN45 GDSC1; GDSC2 2.0548 4.7987 -0.1086 4.4778
SNU-16 GDSC1; GDSC2 2.0619 3.5538 0.4618 1.2949
ECC12 GDSC2 2.1905 3.7058 0.4632 1.1335
SCH GDSC1; GDSC2 2.344 3.5132 0.6103 0.411
SK-GT-2 GDSC1; GDSC2 2.3611 5.9884 -0.4715 6.0056
Fu97 GDSC1; GDSC2 2.3774 4.6181 0.1689 2.3573
NUGC-4 GDSC1; GDSC2 2.5772 4.8427 0.1793 2.0287
TMK-1 GDSC1; GDSC2 2.6146 7.5562 -1.0497 8.8353
OCUM-1 GDSC1; GDSC2 2.6322 8.1535 -1.3248 10.3481
IM95 GDSC1; GDSC2 2.7163 7.5522 -0.9798 8.2261
NUGC-3 GDSC1; GDSC2 2.7188 4.9466 0.2082 1.7147
TGBC11TKB GDSC1; GDSC2 2.7893 5.2478 0.1167 2.0663
SNU-5 GDSC1; GDSC2 3.1222 4.4166 0.5837 0.1589
NCI-N87 GDSC1; GDSC2 3.2725 5.7723 0.1367 1.4523
Hs 746.T GDSC1; GDSC2 3.3312 8.8215 -1.1807 8.1364
RF-48 GDSC1; GDSC2 3.4434 5.3405 0.3764 0.4968
SNU-1 GDSC1; GDSC2 3.5089 5.3402 0.402 0.4023
ECC10 GDSC1; GDSC2 3.7797 5.4618 0.4593 0.2009
23132/87 GDSC1; GDSC2 3.7853 11.9316 -2.3551 13.2034
GCIY GDSC1; GDSC2 3.8203 5.7485 0.3742 0.3472
MKN28 GDSC1; GDSC2 3.8982 6.8863 -0.0211 1.5299
MKN1 GDSC1; GDSC2 4.5513 13.9176 -2.7931 13.6821
MKN7 GDSC1; GDSC2 5.103 14.8112 -2.8592 12.9639
AGS GDSC1; GDSC2 6.107 21.8378 -5.5314 20.3919
RERF-GC-1B GDSC1; GDSC2 6.2222 18.9759 -4.0978 15.7697
SNG-M GDSC1; GDSC2 2.779 5.8566 -0.1549 3.4753
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BHT-101 GDSC1; GDSC2 1.1137 10.8598 -3.8355 25.9198
ASH-3 GDSC1; GDSC2 1.9215 7.2973 -1.4175 12.542
CAL-62 GDSC1; GDSC2 1.9567 3.5918 0.3878 1.8231
IHH-4 GDSC1; GDSC2 2.024 5.0288 -0.2381 5.3097
B-CPAP GDSC1; GDSC2 2.054 4.5096 0.0265 3.6881
ML-1 [Human leukemia] GDSC1; GDSC2 2.4351 4.3843 0.3012 1.6107
FTC-133 GDSC1; GDSC2 2.906 4.2896 0.5485 0.2991
KMH-2 GDSC1; GDSC2 3.0262 4.7116 0.4414 0.5299
CGTH-W-1 GDSC1; GDSC2 3.0522 10.4601 -2.1482 13.7531
WRO GDSC1; GDSC2 3.2893 4.9666 0.4521 0.3726
K5 GDSC1; GDSC2 3.3827 5.2074 0.4011 0.4599
8305C GDSC1; GDSC2 3.4152 4.8954 0.5238 0.1849
TT2609-C02 GDSC1; GDSC2 3.4753 5.3374 0.39 0.4465
HTC-C3 GDSC1; GDSC2 3.4854 5.9669 0.1563 1.1901
TT GDSC1; GDSC2 4.7019 15.6419 -3.513 16.3227
8505C GDSC1; GDSC2 6.5108 16.6888 -2.8669 10.7331
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-15A GDSC1; GDSC2 1.4236 4.4306 -0.3763 7.5508
CAL-33 GDSC1; GDSC2 2.2077 8.5442 -1.8191 14.0351
BICR 10 GDSC1 2.2267 7.6132 -1.3483 13.8199
PCI-38 GDSC1 2.2341 8.8535 -1.9517 17.4569
HSC-3 GDSC1; GDSC2 2.2378 3.8917 0.4088 1.334
SKN-3 GDSC1; GDSC2 2.2485 4.6443 0.0832 3.0227
BICR 78 GDSC1; GDSC2 2.2574 10.0784 -2.5386 17.5095
FaDu GDSC1; GDSC2 2.2779 6.2078 -0.6313 7.1174
Detroit 562 GDSC1; GDSC2 2.4217 5.3221 -0.1226 3.8808
JHU-011 GDSC1; GDSC2 2.4358 8.9969 -1.8742 13.773
SAT [Human HNSCC] GDSC1; GDSC2 2.5686 15.1814 -4.8296 25.3456
BICR 31 GDSC2 2.6075 5.0618 0.1006 2.3848
BICR 22 GDSC1; GDSC2 2.6462 5.7456 -0.1818 3.8327
HSC-2 GDSC1; GDSC2 2.719 3.8905 0.6199 0.2088
CAL-27 GDSC1; GDSC2 2.7405 4.2066 0.5134 0.4759
HSC-4 GDSC1; GDSC2 2.7959 13.1416 -3.6468 20.8588
HO-1-N-1 GDSC1; GDSC2 2.8234 5.6814 -0.0526 2.8709
PCI-30 GDSC1; GDSC2 2.8273 4.9355 0.266 1.3366
SCC-4 GDSC1; GDSC2 2.8281 6.592 -0.4593 5.0647
JHU-029 GDSC1; GDSC2 2.834 8.1879 -1.2044 9.2469
NCI-H3118 GDSC1; GDSC2 2.8758 5.1336 0.2081 1.5405
OSC-20 GDSC1; GDSC2 2.9081 4.7717 0.3685 0.8532
SCC-9 GDSC1; GDSC2 3.0226 4.9273 0.3581 0.8052
OSC-19 GDSC1; GDSC2 3.0323 4.5137 0.5163 0.3242
PCI-06A GDSC1; GDSC2 3.1922 5.5027 0.2077 1.2366
PE/CA-PJ15 GDSC1; GDSC2 3.2398 5.0347 0.4079 0.512
SCC-25 GDSC1; GDSC2 3.2599 5.3157 0.3106 0.8035
BB49-HNC GDSC1 3.2846 5.0593 0.4166 0.5796
SAS GDSC1; GDSC2 3.51 7.6808 -0.5532 4.474
BB30-HNC GDSC1; GDSC2 3.5702 5.725 0.2852 0.6911
HO-1-u-1 GDSC1; GDSC2 3.5778 9.8456 -1.5034 9.3852
BHY GDSC1; GDSC2 3.58 6.4402 0.011 1.6855
DOK GDSC1; GDSC2 3.6501 5.8304 0.2784 0.6663
PCI-04B GDSC1; GDSC2 3.9141 6.2216 0.2398 0.6374
UPCI-SCC-090 GDSC1; GDSC2 3.955 18.2745 -5.3154 23.7326
KOSC-2 GDSC1; GDSC2 3.9893 6.2251 0.268 0.5273
Ca9-22 GDSC1; GDSC2 4.1079 6.127 0.3475 0.3082
JHU-022 GDSC1; GDSC2 4.2877 14.7353 -3.3585 16.5221
LB771-HNC GDSC1; GDSC2 4.6668 17.5091 -4.4344 19.6622
KON GDSC1; GDSC2 4.8591 17.4093 -4.2539 18.6957
SCC-15 GDSC1; GDSC2 7.0489 19.3176 -3.7434 13.2389
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
T24 GDSC1; GDSC2 -0.9724 11.8881 -6.1641 38.0869
KU-19-19 GDSC1; GDSC2 1.4084 2.9661 0.333 3.1734
RT-112 GDSC1; GDSC2 1.6495 3.1157 0.422 2.146
BFTC-905 GDSC1; GDSC2 1.7341 4.2457 -0.0592 4.8478
UM-UC-3 GDSC1; GDSC2 1.9447 12.5929 -4.0292 24.3322
J82 GDSC1; GDSC2 2.0943 5.4119 -0.3741 5.9755
HT-1376 GDSC1; GDSC2 2.3998 4.7739 0.1124 2.6235
639V GDSC1; GDSC2 2.4318 7.9016 -1.3426 10.8956
SW780 GDSC1; GDSC2 2.4712 4.277 0.3645 1.2732
HT-1197 GDSC1; GDSC2 2.6358 4.6542 0.289 1.4355
CAL-29 GDSC1; GDSC2 2.6684 4.3725 0.4186 0.8565
647V GDSC1; GDSC2 2.8836 4.4567 0.4784 0.4996
SW1710 GDSC1; GDSC2 3.4723 5.2488 0.4208 0.3726
5637 GDSC1; GDSC2 4.152 6.468 0.2432 0.5188
RT-4 GDSC1; GDSC2 4.8339 18.2463 -4.6748 20.1184
TCCSUP GDSC1; GDSC2 6.4392 23.681 -6.1902 21.5811
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NEC8 GDSC1; GDSC2 0.0456 7.5072 -3.0796 26.4264
SW756 GDSC1; GDSC2 1.0307 12.741 -4.8449 29.2906
DSH1 GDSC1; GDSC2 1.6954 5.2854 -0.5944 8.2204
TC-YIK GDSC1; GDSC2 2.2787 4.4202 0.2013 2.332
HeLa GDSC1; GDSC2 2.2946 8.6265 -1.7955 13.6976
LB831-BLC GDSC1; GDSC2 2.3931 4.7654 0.1124 2.6337
SKN GDSC1; GDSC2 2.5733 5.6986 -0.2037 4.0757
HEC-1 GDSC1; GDSC2 2.7165 7.921 -1.1556 9.2198
C-33 A GDSC1; GDSC2 2.7842 7.5468 -0.9326 7.8208
JEG-3 GDSC1; GDSC2 2.7903 4.4184 0.454 0.6359
HEY GDSC1; GDSC2 2.8666 9.6512 -1.886 12.8425
NT2-D1 GDSC1; GDSC2 2.9125 8.5238 -1.3122 9.6802
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 2.9406 8.3709 -1.2207 9.1182
SKG-IIIa GDSC1; GDSC2 2.947 7.217 -0.6746 6.057
HT-3 GDSC1; GDSC2 2.9864 10.4162 -2.173 14.0211
OVMIU GDSC1; GDSC2 2.9929 10.8531 -2.3807 15.0122
PEO1 GDSC1; GDSC2 3.0147 15.7984 -4.7946 24.2213
OVCA420 GDSC1; GDSC2 3.0482 4.8701 0.3909 0.6755
DoTc2 4510 GDSC1; GDSC2 3.1044 10.0759 -1.9264 12.5286
JAR GDSC1; GDSC2 3.1844 4.9098 0.4317 0.4736
Ca Ski GDSC1; GDSC2 3.1893 8.4206 -1.0831 7.8724
MS751 GDSC1; GDSC2 3.2048 8.2991 -1.0165 7.4787
PA-1 GDSC1; GDSC2 3.2648 4.7685 0.5133 0.2464
ACC-OV7 GDSC1; GDSC2 3.4423 6.2164 0.0368 1.7094
SW962 GDSC1; GDSC2 3.4552 5.0235 0.4939 0.2261
SW954 GDSC1; GDSC2 3.5852 5.4251 0.4007 0.375
BPH-1 GDSC1; GDSC2 3.602 6.4464 0.0187 1.6328
CAL-39 GDSC1; GDSC2 3.6421 5.8274 0.2763 0.6771
NCC-IT GDSC2 3.7295 5.4306 0.4521 0.2254
UWB1.289 GDSC1; GDSC2 3.7585 6.5972 0.0303 1.448
ME-180 GDSC1; GDSC2 3.7738 8.1044 -0.5937 4.3
JHOS-3 GDSC1; GDSC2 3.882 6.2515 0.2159 0.7229
OVCA433 GDSC1; GDSC2 3.9508 11.4616 -2.0235 11.2967
KGN GDSC1; GDSC2 4.058 5.8388 0.429 0.1847
OV17R GDSC1; GDSC2 4.2475 15.0253 -3.5254 17.2523
PWR-1E GDSC1; GDSC2 4.8161 16.744 -3.9636 17.7697
C-4-I GDSC1; GDSC2 5.1476 19.6753 -5.1477 20.972
SiSo GDSC1; GDSC2 5.7081 16.8249 -3.4175 14.1585
SiHa GDSC1; GDSC2 5.7131 16.2059 -3.1262 13.0147
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4946).