Details of the Drug

General Information of Drug (ID: DMASP9Z)

Drug Name
SU11274
Synonyms Met kinase Inhibitor; SU-11274
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 568.1
Logarithm of the Partition Coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C28H30ClN5O4S
IUPAC Name
(3Z)-N-(3-chlorophenyl)-3-[[3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl]methylidene]-N-methyl-2-oxo-1H-indole-5-sulfonamide
Canonical SMILES
CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)/C=C\\3/C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O
InChI
InChI=1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35)/b23-16-
InChIKey
FPYJSJDOHRDAMT-KQWNVCNZSA-N
Cross-matching ID
PubChem CID
9549297
CAS Number
658084-23-2
TTD ID
D0E1QI

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Proto-oncogene c-Met (MET) TTNDSF4 MET_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Proto-oncogene c-Met (MET) DTT MET 1.08E-03 -0.24 -0.4
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 5.1861 9.392 1.6928 7.6431
EW-18 GDSC1 1.5962 3.7929 1.3007 23.9582
SK-N-MC CTRP2 1.6389 2.0465 1.6389 29.3499
NOS-1 [Human HNSCC] GDSC1 1.9785 3.7757 1.7203 18.958
ES7 GDSC1 2.2127 5.1548 1.3879 20.1304
SK-ES-1 GDSC1; CTRP2 2.2217 3.4951 2.2201 25.4728
MHH-ES-1 GDSC1; CTRP2 2.386 4.5489 2.2619 19.4317
CADO-ES1 GDSC1 2.4914 4.2566 2.0738 13.7528
SK-PN-DW GDSC1 2.7052 5.538 1.6845 15.693
ES5 GDSC1 2.7399 7.7384 0.6324 22.7362
EW-7 GDSC1 2.743 3.8196 2.5213 9.2051
CAL-72 GDSC1 2.8502 3.365 2.8015 6.6444
ES1 GDSC1 2.8547 4.3779 2.3846 9.6948
H-EMC-SS GDSC1 2.882 6.0346 1.6038 15.545
NY GDSC1 2.9012 3.9202 2.6417 7.5325
EW-13 GDSC1 2.9813 8.1244 0.6529 21.6122
EW-16 GDSC1 3.0669 5.2265 2.1702 10.4512
ES8 GDSC1 3.5627 5.8527 2.2755 7.7986
EW-1 GDSC1 3.5676 5.8997 2.256 7.9344
CHSA8926 GDSC1 3.5931 5.1342 2.6561 4.7204
SaOS-2 GDSC1; CTRP2 3.7606 5.2271 3.7183 15.358
EW-22 GDSC1 4.0606 10.6643 0.2712 19.8758
HOS GDSC1; CTRP2 4.0628 7.2717 3.4562 15.4296
ES6 GDSC1 4.3809 6.9522 2.3235 5.088
EW-3 GDSC1 4.5766 13.7417 -0.8579 23.6441
EW-24 GDSC1 4.6531 6.0392 2.8797 0.9498
A-673 GDSC1; CTRP2 5.6637 11.177 3.1544 12.854
TC-71 GDSC1 5.6834 7.2847 2.8362 0.3663
SJSA-1 GDSC1; CTRP2 5.8839 10.85 3.5066 10.9602
ES4 GDSC1 5.9038 8.0139 2.6573 0.817
TC71 CTRP2 6.0254 11.4947 3.3034 11.5178
HuO-3N1 GDSC1 6.3737 13.842 0.3641 13.0151
HuO9 GDSC1 6.7655 18.2417 -1.4725 20.4
CAL-78 GDSC1; CTRP2 6.7869 10.944 4.1825 6.5015
MG-63 GDSC1; CTRP2 6.9691 11.8063 3.8931 7.3966
Hs 822.T CTRP2 7.3851 8.2975 5.7484 0.1074
Hs 888.T CTRP2 7.5488 12.5923 3.9235 6.384
U2OS GDSC1; CTRP2 8.3721 21.64 -0.6702 17.2408
SW1353 CTRP2 8.3845 9.9292 5.5446 0.1649
G-292 clone A141B1 GDSC1; CTRP2 8.6267 10.4981 5.4338 0.2672
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 207 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 2.6461 5.1374 2.5382 23.0078
JK1 CTRP2 9.3752 11.806 5.2506 0.3544
JM1 GDSC1; CTRP2 3.6128 5.8691 3.4365 16.8121
MV4-11 GDSC1; CTRP2 -0.553 3.0603 -0.6115 44.0837
EoL-1 GDSC1; CTRP2 -0.0909 1.9103 -0.0931 40.8812
NALM-6 GDSC1; CTRP2 0.7116 2.8154 0.7043 35.5521
SU-DHL-16 GDSC1 1.1858 3.3027 1.002 28.3046
U-937 CTRP2 1.3344 3.1203 1.3294 31.3953
ALL-SIL GDSC1; CTRP2 1.3488 3.0673 1.345 31.2952
MOLT-16 GDSC1 1.3576 4.4686 0.7953 28.589
CTV-1 GDSC1 1.3796 4.1919 0.9245 27.659
GDM-1 GDSC1; CTRP2 1.4962 3.3527 1.4885 30.3264
Pfeiffer CTRP2 1.4998 3.8181 1.4718 30.3702
SEM CTRP2 1.5185 2.9574 1.5172 30.1565
F-36P CTRP2 1.5365 5.5114 1.2594 30.9543
697 GDSC1; CTRP2 1.5755 2.6202 1.5754 29.773
Kasumi-1 CTRP2 1.6117 2.4343 1.6117 29.5311
KMS-11 GDSC1; CTRP2 1.6125 4.0009 1.5763 29.6471
Toledo CTRP2 1.6361 2.3806 1.6361 29.3688
EB1 CTRP2 1.6394 2.476 1.6394 29.3468
KMS-20 CTRP2 1.6415 3.8778 1.615 29.4215
MOLT-3 CTRP2 1.6747 2.1563 1.6747 29.1118
SUP-M2 GDSC1; CTRP2 1.6885 2.5793 1.6885 29.0196
REC-1 CTRP2 1.7079 3.8287 1.6865 28.9617
OCI-AML-2 GDSC1; CTRP2 1.7302 4.7999 1.6083 29.1522
Ku812 GDSC1; CTRP2 1.7564 4.3361 1.6217 23.9623
SIG-M5 GDSC1; CTRP2 1.7677 6.7681 1.1612 30.5116
MOLT-4 GDSC1 1.837 3.7535 1.5749 20.7435
OPM-2 GDSC1; CTRP2 1.8496 4.2233 1.806 28.0928
MLMA GDSC1 1.8618 2.4743 1.8592 18.6955
EM-2 GDSC1; CTRP2 1.8691 3.0336 1.8687 27.818
RPMI-8402 GDSC1; CTRP2 1.8893 3.9213 1.8688 27.7503
CCRF-CEM GDSC1 1.8893 3.0277 1.8316 18.7059
A3/Kawakami GDSC1; CTRP2 1.943 4.3335 1.8939 27.4891
KMS-26 CTRP2 1.956 3.7638 1.9446 27.2755
KE-97 CTRP2 1.9601 3.1339 1.9596 27.2119
HuT 78 CTRP2 1.9754 5.9266 1.6354 28.2671
CMK CTRP2 1.984 3.8557 1.9696 27.0992
TALL-1 [Human adult T-ALL] CTRP2 1.9872 4.8927 1.8695 27.4282
MOLM-13 GDSC1 2.0071 4.7052 1.3799 21.2101
Namalwa CTRP2 2.0122 3.6529 2.0055 26.8856
NU-DUL-1 GDSC1; CTRP2 2.0282 3.7942 2.0174 26.7923
SUP-T11 CTRP2 2.0742 3.0032 2.0741 26.4502
OCI-Ly3 CTRP2 2.0749 2.9762 2.0748 26.4458
Kasumi-2 CTRP2 2.0799 4.8229 1.9797 26.7513
Daudi GDSC1; CTRP2 2.0862 3.0939 2.086 26.3706
CML-T1 CTRP2 2.1156 3.1052 2.1154 26.1749
Hs 445 GDSC1 2.1438 2.9106 2.1228 15.2875
QIMR-WIL GDSC1 2.2684 5.7237 1.1772 21.3361
SET-2 CTRP2 2.3362 3.2561 2.3361 24.7051
PF-382 GDSC1; CTRP2 2.3395 4.5384 2.2913 24.8448
RCH-ACV GDSC1; CTRP2 2.3431 3.3932 2.3427 24.6597
P30/OHK GDSC1 2.3659 5.0219 1.6018 17.8505
DEL GDSC1; CTRP2 2.3718 3.0722 2.3718 24.4671
DND-41 GDSC1; CTRP2 2.3758 7.4068 1.6007 27.1328
CA46 GDSC1; CTRP2 2.3899 3.5031 2.3891 24.3495
NU-DHL-1 CTRP2 2.3996 3.1348 2.3996 24.2824
SUP-HD1 GDSC1; CTRP2 2.427 4.127 2.4127 24.1477
L-363 GDSC1; CTRP2 2.4353 4.8992 2.3489 24.3374
BDCM CTRP2 2.4836 5.1289 2.3646 24.1282
BV-173 GDSC1; CTRP2 2.5238 4.0067 2.5165 23.4791
H9 GDSC1 2.5257 7.5334 0.5406 24.2071
RS4;11 GDSC1; CTRP2 2.53 5.3449 2.3749 23.9448
ALL-PO GDSC1 2.5517 12.6044 -1.9543 34.107
JSC-1 GDSC1 2.5556 9.3156 -0.3144 28.4478
MY-M12 GDSC1 2.5671 3.7472 2.3637 11.2538
MOTN-1 CTRP2 2.5792 4.3064 2.5602 23.1493
BL-70 CTRP2 2.5841 2.9936 2.5841 23.053
HPB-ALL CTRP2 2.5851 4.5844 2.5453 23.1804
RPMI-8866 GDSC1 2.5897 5.6068 1.5422 17.2589
Karpas-45 GDSC1 2.6011 3.7827 2.3862 10.9148
P12-Ichikawa GDSC1; CTRP2 2.6217 3.3912 2.6217 22.8027
MOLP-8 GDSC1; CTRP2 2.6278 5.824 2.3736 23.6422
TF-1 CTRP2 2.632 3.0598 2.632 22.7338
THP-1 GDSC1; CTRP2 2.6435 3.795 2.6419 22.6623
P32/ISH GDSC1 2.703 4.6353 2.1149 12.4404
NK-92MI GDSC1 2.7531 11.3833 -1.1705 30.9939
L-428 GDSC1; CTRP2 2.7639 5.0539 2.678 22.1473
RPMI-6666 GDSC1; CTRP2 2.7648 4.4841 2.7415 21.9275
KOPN-8 GDSC1 2.7691 12.432 -1.6798 32.5487
MHH-CALL-3 CTRP2 2.7831 4.2808 2.7718 21.765
NCI-H929 CTRP2 2.7943 6.8356 2.2537 23.565
ST486 GDSC1; CTRP2 2.7985 4.4105 2.7811 21.6832
DoHH2 GDSC1 2.829 3.3903 2.7712 6.9712
MHH-PREB-1 GDSC1 2.8329 12.303 -1.5605 31.9584
TUR GDSC1 2.8355 5.3237 1.9107 13.417
HH [Human lymphoma] GDSC1; CTRP2 2.9361 4.2135 2.9306 20.726
HuNS1 CTRP2 2.9367 6.1604 2.6205 21.8107
SR GDSC1; CTRP2 2.9524 4.3433 2.9429 20.6309
OCI-Ly19 GDSC1; CTRP2 2.9739 5.258 2.8708 20.8079
HDLM-2 GDSC1; CTRP2 2.9921 5.796 2.7777 21.0782
BL-41 GDSC1 3.0309 3.7199 2.8629 5.2548
NKM-1 GDSC1 3.0453 6.6269 1.455 15.9774
A4/Fukuda GDSC1; CTRP2 3.1018 4.5432 3.0872 19.6529
GR-ST GDSC1 3.1733 6.347 1.7058 13.6128
ME1 GDSC1 3.1945 3.7931 2.9918 3.5182
SUP-T1 GDSC1; CTRP2 3.2249 7.6922 2.4009 21.7713
Karpas-231 GDSC1 3.2378 4.3545 2.7552 5.1862
KMS-12-BM GDSC1; CTRP2 3.253 5.5018 3.1272 19.0287
Mono-Mac-6 GDSC1 3.3025 7.5534 1.2127 16.7054
U266B1 GDSC1; CTRP2 3.3231 5.9138 3.1091 18.8745
L-540 GDSC1; CTRP2 3.4301 4.8333 3.4091 17.4872
LP-1 GDSC1; CTRP2 3.4841 6.1213 3.2289 17.9518
DG-75 GDSC1 3.5564 5.0208 2.6842 4.617
CTB-1 GDSC1 3.5726 6.8934 1.7645 11.7082
VAL GDSC1 3.5818 8.4499 0.9948 17.1542
DB GDSC1; CTRP2 3.5877 5.8427 3.4156 16.964
CESS GDSC1 3.5899 5.6298 2.4078 6.6728
BALL-1 GDSC1 3.6192 7.2028 1.6474 12.425
BC-1 GDSC1 3.6661 6.7745 1.8979 10.3763
KO52 CTRP2 3.6828 6.8444 3.2116 17.4296
JeKo-1 CTRP2 3.713 5.201 3.671 15.6739
JURL-MK1 GDSC1; CTRP2 3.7206 5.5943 3.6156 15.842
GA-10 GDSC1; CTRP2 3.7307 4.3916 3.7304 15.4151
RL GDSC1; CTRP2 3.7653 4.4135 3.765 15.1846
LC4-1 GDSC1 3.8693 6.5311 2.1734 7.6123
WIL2 NS GDSC1 3.9822 13.0187 -0.9638 25.9166
K-562 GDSC1; CTRP2 3.9934 7.2072 3.4081 15.8059
Sc-1 GDSC1 4.0526 12.0524 -0.4261 23.4053
KE-37 GDSC1 4.066 6.4269 2.3645 5.5889
SK-MM-2 GDSC1; CTRP2 4.0871 6.1653 3.8742 13.7889
KMS-27 CTRP2 4.1253 8.4576 3.0155 16.9784
KYO-1 CTRP2 4.1287 6.3267 3.8703 13.6789
OCI-M1 GDSC1; CTRP2 4.1439 9.6424 2.4909 18.9727
HEL 92.1.7 CTRP2 4.1619 6.5777 3.823 13.757
JJN-3 GDSC1; CTRP2 4.1796 15.828 -0.4769 28.3949
SUP-B15 GDSC1; CTRP2 4.1853 6.808 3.7656 13.9057
KY821 GDSC1 4.1859 8.7877 1.297 13.0871
KMS-18 CTRP2 4.2115 8.02 3.2972 15.648
Loucy GDSC1 4.246 6.592 2.4061 4.8131
Jiyoye GDSC1 4.268 6.6437 2.3961 4.8327
Karpas-620 GDSC1 4.4351 11.6126 0.089 19.6545
BC-3 GDSC1 4.4527 6.5321 2.5622 3.2283
Ramos.2G6.4C10 GDSC1 4.5096 9.3299 1.2674 12.3163
EB2 GDSC1 4.5435 6.9076 2.4452 3.8501
Farage GDSC1 4.5648 12.2743 -0.1401 20.4254
HL-60 GDSC1; CTRP2 4.592 7.179 4.0515 11.6812
KG-1 GDSC1 4.7239 7.6875 2.1964 5.2018
VL51 GDSC1 4.7619 9.89 1.1737 12.2251
Granta-519 GDSC1; CTRP2 4.7914 7.8457 3.9651 11.5027
Jurkat GDSC1; CTRP2 4.7985 8.2915 3.2117 8.7744
OCI-AML-3 GDSC1; CTRP2 4.8192 6.6612 4.4998 9.327
TK [Human B-cell lymphoma] GDSC1 4.8206 6.6503 2.7101 1.6546
SU-DHL-5 GDSC1 4.8218 9.4504 1.427 10.3613
ATN-1 GDSC1 4.8283 6.8765 2.6185 2.1835
HD-MY-Z CTRP2 4.8547 6.631 4.5493 9.0386
Karpas-422 GDSC1 4.8893 6.5571 2.7813 1.182
MN-60 GDSC1 4.9428 7.5957 2.367 3.5868
HEL GDSC1; CTRP2 4.9797 10.9723 2.0264 13.6089
ML-2 GDSC1 5.0381 12.7041 -0.001 18.3347
HAL-01 GDSC1 5.0543 10.0778 1.2835 10.7144
MJ CTRP2 5.1343 10.8598 2.8417 15.2511
SCC-3 GDSC1 5.1354 6.0937 3.0501 0.0915
WSU-NHL GDSC1 5.1467 7.0525 2.7016 1.295
HC-1 GDSC1 5.2704 13.1591 -0.056 17.9691
JVM-2 GDSC1 5.275 9.4773 1.7085 7.3347
AML-193 CTRP2 5.29 14.4695 1.1878 21.0158
BE-13 GDSC1 5.3084 10.0017 1.4853 8.7496
RC-K8 GDSC1 5.3177 7.0031 2.7953 0.7157
YT GDSC1 5.3246 6.9377 2.8225 0.608
OCI-AML-5 GDSC1; CTRP2 5.3924 13.5826 1.719 18.9582
IM-9 GDSC1 5.4532 6.6341 2.9782 0.1344
ROS-50 GDSC1 5.462 14.6904 -0.6662 20.3294
MOLP-2 CTRP2 5.4825 11.1998 2.9846 13.9217
ARH-77 GDSC1 5.6362 7.235 2.8361 0.3878
MEG-01 GDSC1 5.7584 8.0939 2.5653 1.318
U-698-M GDSC1 5.8872 14.1825 -0.1205 16.6803
OCI-Ly10 CTRP2 6.1601 8.7757 4.7739 5.1211
KMOE-2 GDSC1 6.2433 8.0574 2.7714 0.308
EJM GDSC1; CTRP2 6.3011 11.5795 3.4877 10.2337
PL-21 GDSC1 6.4408 9.0281 2.4978 1.0335
KCL-22 GDSC1; CTRP2 6.4564 8.9852 4.0892 2.1123
Hs 611.T CTRP2 6.567 11.0195 3.9778 7.7225
SKM-1 GDSC1; CTRP2 6.8013 10.3439 4.4882 5.2165
RPMI-8226 GDSC1; CTRP2 6.9095 13.811 2.8564 11.6879
MM1.S CTRP2 7.0239 10.3216 4.6568 4.1908
JVM-3 GDSC1; CTRP2 7.0301 9.0841 4.3422 0.7534
SU-DHL-10 GDSC1; CTRP2 7.0609 8.0137 5.7235 0.2646
L-1236 GDSC1; CTRP2 7.0697 14.1555 2.8084 11.5987
MC116 GDSC1; CTRP2 7.129 8.0664 5.7322 0.2153
Karpas-299 GDSC1; CTRP2 7.2686 13.7737 3.1465 9.9305
KHM-1B CTRP2 7.2871 8.9379 4.5049 0.2644
MOLT-13 GDSC1; CTRP2 7.3703 14.7755 2.7285 11.4028
NOMO-1 GDSC1; CTRP2 7.3754 17.3424 1.4627 16.0251
KM-H2 GDSC1; CTRP2 7.419 9.357 4.4036 0.4126
NB4 GDSC1; CTRP2 7.5675 8.5816 5.716 0.1114
SU-DHL-1 GDSC1; CTRP2 7.6292 8.6121 5.7279 0.085
HT GDSC1; CTRP2 7.6511 8.7435 5.6901 0.1282
WSU-DLCL2 GDSC1; CTRP2 7.7081 8.7704 5.7016 0.1015
P31/FUJ GDSC1; CTRP2 7.8235 8.8775 5.706 0.0774
AMO1 GDSC1; CTRP2 7.8256 9.0019 5.6638 0.1258
P3HR-1 CTRP2 7.8399 16.5753 2.1901 12.6638
Raji GDSC1; CTRP2 7.8563 9.1551 5.621 0.1796
MOLM-16 CTRP2 7.926 9.1713 5.6414 0.1341
Reh GDSC1; CTRP2 7.9572 14.8138 3.1334 8.9085
PL21 CTRP2 8.0684 10.7878 5.0714 1.4681
SU-DHL-4 GDSC1; CTRP2 8.0702 9.3094 5.6458 0.102
Peer CTRP2 8.0894 9.637 5.5371 0.2505
ME1 CTRP2 8.2086 9.9826 5.4575 0.3566
Ki-JK CTRP2 8.3733 10.0991 5.48 0.263
LAMA-84 GDSC1; CTRP2 8.4162 15.8642 2.1197 7.4706
SU-DHL-8 GDSC1; CTRP2 8.5334 9.9628 5.5864 0.0934
SU-DHL-6 GDSC1; CTRP2 8.6812 9.9979 5.6253 0.0487
EHEB GDSC1; CTRP2 8.7427 10.6787 5.4133 0.2683
Ri-1 CTRP2 8.8226 11.2498 5.2349 0.5723
MHH-CALL-4 CTRP2 8.9577 10.5936 5.5209 0.0981
KMM-1 CTRP2 8.9693 11.0178 5.3781 0.2639
⏷ Show the Full List of 207 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 5.4808 7.9123 4.6074 7.2237
TE15 CTRP2 6.314 9.439 4.5663 5.7116
TE-15 GDSC1 2.3846 4.7904 1.7268 16.8417
TE-8 GDSC1 2.8834 4.8598 2.1814 11.1292
KYSE-70 GDSC1; CTRP2 3.5521 8.3443 2.4759 20.5802
KYSE-30 CTRP2 4.3364 14.7861 0.1796 26.2838
KYSE-270 GDSC1 4.3743 12.0011 -0.1499 21.0622
EC-GI-10 GDSC1; CTRP2 4.4102 6.7038 4.0456 12.2074
OE21 GDSC1; CTRP2 4.412 6.8123 4.007 12.3487
KYSE-140 GDSC1; CTRP2 4.9129 8.7705 3.0707 9.1592
T.T GDSC1 4.9751 7.5765 2.3936 3.3542
TE-4 GDSC1; CTRP2 5.0937 8.9951 3.7174 11.7807
TE-5 GDSC1; CTRP2 5.1309 6.4273 4.9219 6.8434
KYSE-150 GDSC1; CTRP2 5.6569 11.5654 2.9547 13.6771
KYSE-410 GDSC1; CTRP2 5.8953 9.3477 4.2669 7.7637
TE-6 GDSC1; CTRP2 6.3698 12.4857 3.0908 11.7264
TE-11 GDSC1; CTRP2 7.0047 12.3298 3.6617 8.2854
KYSE-450 GDSC1; CTRP2 7.6638 8.8737 5.6484 0.1888
OE19 GDSC1; CTRP2 7.832 9.4476 5.5031 0.4129
KYSE-180 GDSC1; CTRP2 7.9953 14.7798 2.3611 7.0805
TE-9 GDSC1; CTRP2 8.1097 13.2584 3.9791 5.3996
TE-10 GDSC1; CTRP2 8.1741 12.27 4.4764 3.4376
TE-14 CTRP2 8.1843 11.9796 4.6134 2.9272
KYSE-520 GDSC1; CTRP2 8.6581 10.4986 5.4455 0.2411
TE-1 GDSC1; CTRP2 8.7379 13.9789 4.0336 4.4419
COLO 680N GDSC1; CTRP2 8.8012 10.2875 5.5698 0.0759
OE33 GDSC1; CTRP2 10.8371 22.8513 1.2206 11.7156
KYSE-510 GDSC1; CTRP2 13.1183 25.9742 1.1749 9.2973
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 10.459 22.2058 1.2802 12.0066
KP-4 GDSC1; CTRP2 3.6929 6.9639 3.1792 17.5221
KP-1N GDSC1 4.2752 6.3573 2.5348 3.807
MZ-PC-1 GDSC1 4.6145 11.7066 0.1776 18.6348
QGP-1 GDSC1 4.6157 7.9968 1.9828 6.9816
MIA PaCa-2 GDSC1; CTRP2 5.1113 8.8289 3.8145 11.3417
Panc 08.13 GDSC1; CTRP2 5.2008 8.4481 4.0832 10.0299
PL4 GDSC1 5.2798 7.5654 2.5563 1.8991
Panc 03.27 GDSC1; CTRP2 5.3883 9.5046 3.7411 11.0214
KP-3 GDSC1; CTRP2 5.4062 9.3514 3.1845 7.6526
Panc 10.05 GDSC1; CTRP2 6.3916 10.1475 4.2745 6.7943
SW1990 GDSC1; CTRP2 6.4618 9.0749 4.8614 4.2226
HuP-T4 GDSC1; CTRP2 7.0046 12.1201 3.7649 7.8637
PaTu 8902 GDSC1; CTRP2 7.0086 14.8156 2.4342 13.1505
PSN1 GDSC1; CTRP2 7.1461 11.5885 4.1282 6.1559
SNU-213 CTRP2 7.2194 8.5728 4.6085 0.1268
KP-2 CTRP2 7.4766 10.422 4.9027 2.6375
DAN-G GDSC1; CTRP2 7.4952 20.5856 -0.0553 20.5435
PaTu 8988s CTRP2 7.5781 10.9054 4.742 3.1257
Capan-1 GDSC1; CTRP2 7.641 10.8672 4.798 2.8415
BxPC-3 GDSC1; CTRP2 7.7248 14.1372 3.2985 8.6104
CFPAC-1 GDSC1; CTRP2 7.8388 9.5164 5.4796 0.4632
Capan-2 GDSC1; CTRP2 7.8797 11.138 4.8157 2.5161
SU.86.86 GDSC1; CTRP2 7.9512 9.3637 5.5824 0.2151
HPAF-II GDSC1; CTRP2 7.9632 9.9821 4.3885 0.2681
HPAC GDSC1; CTRP2 7.9814 9.5722 5.518 0.3213
Panc 04.03 GDSC1; CTRP2 7.9879 14.1049 3.4962 7.4477
YAPC GDSC1; CTRP2 8.054 9.5813 5.5436 0.2502
SUIT-2 GDSC1; CTRP2 8.1284 19.7459 0.8434 16.7912
PK-59 CTRP2 8.1413 12.3587 4.4164 3.6966
TCC-Pan2 CTRP2 8.1805 9.7993 5.5137 0.2631
PaTu 8988t GDSC1; CTRP2 8.1874 16.643 2.4074 11.3182
HuP-T3 GDSC1; CTRP2 8.2033 11.0551 5.0272 1.5006
Panc 05.04 CTRP2 8.2409 10.9923 5.0725 1.3316
Hs 766T GDSC1; CTRP2 8.3995 9.9642 5.5379 0.1706
Panc 02.03 GDSC1; CTRP2 8.4423 15.3892 3.1876 8.0065
PK-45H CTRP2 8.7292 10.2372 5.5619 0.0905
L3.3 CTRP2 8.8099 9.8663 5.7104 0.0102
AsPC-1 GDSC1; CTRP2 8.8899 10.8271 5.4159 0.2285
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 75 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 2.4237 7.6363 1.5673 27.101
MZ-MEL-7 GDSC1 2.5613 4.2063 2.1677 12.715
CJM [Human melanoma] CTRP2 2.6376 2.9685 2.6376 22.6964
WM278 GDSC1 2.6464 4.1575 2.2764 11.4912
HT-144 GDSC1; CTRP2 2.727 3.08 2.727 22.1011
Malme-3M CTRP2 2.7661 7.3896 2.0266 24.4662
SH-4 GDSC1 2.7806 3.5669 2.6601 8.0108
MMAc-SF GDSC1 2.8109 3.3245 2.7695 7.0859
Mel Ho GDSC1; CTRP2 2.8203 3.5737 2.8193 15.8784
A-431 GDSC1 2.8224 3.6485 2.6741 7.6892
CHL-1 GDSC1 2.8479 3.8268 2.6277 7.8972
MZ-MEL-2 GDSC1 2.9091 3.5739 2.7953 6.3656
WM266-4 CTRP2 3.2339 4.8729 3.2002 18.8374
LB2518-MEL GDSC1 3.468 4.3971 2.9257 3.0106
COLO 783 GDSC1 3.5333 4.9532 2.7 4.5674
SK-MEL-3 GDSC1; CTRP2 3.5538 4.8978 3.5333 16.6613
SK-MEL-31 CTRP2 3.6018 5.9177 3.4122 16.9328
SK-MEL-24 GDSC1; CTRP2 3.61 4.5196 3.6077 16.2261
DJM-1 GDSC1 3.6664 5.3056 2.6263 4.7253
WM115 GDSC1; CTRP2 3.7063 4.263 3.7063 15.5766
COLO 792 GDSC1; CTRP2 3.7786 6.6183 3.3941 16.4703
451Lu GDSC1 3.9295 6.305 2.3279 6.249
CP50-MEL-B GDSC1 4.0939 5.6981 2.728 2.833
WT2-iPS GDSC1; CTRP2 4.1931 5.5311 4.1375 12.5232
COLO 679 GDSC1 4.5869 6.9895 2.4338 3.838
LB373-MEL-D GDSC1 4.6097 11.7584 0.1485 18.8049
GAK GDSC1 4.703 6.5925 2.6747 2.0382
Hs 938.T GDSC1 4.7062 6.117 2.873 0.9251
UACC-257 GDSC1; CTRP2 4.7387 6.5595 4.4518 9.7368
MeWo GDSC1; CTRP2 4.8525 6.8952 4.4421 9.4572
SK-MEL-5 GDSC1; CTRP2 5.0375 8.1139 4.0851 10.4095
SK-MEL-1 GDSC1; CTRP2 5.151 8.0452 4.2282 9.5535
VMRC-MELG GDSC1 5.1633 6.6007 2.8823 0.5007
WM1552C GDSC1 5.3536 11.6273 0.7435 13.3352
M14 GDSC1 5.3632 7.3479 2.6824 1.1617
SK-MEL-2 GDSC1; CTRP2 5.5608 6.0475 5.5157 3.3796
CP66-MEL GDSC1 5.6119 6.7352 2.9987 0.077
WM35 GDSC1 5.6539 7.7538 2.6515 1.0331
WM983B CTRP2 5.6837 8.3739 4.567 6.9432
G-mel GDSC1 5.7866 7.2857 2.8736 0.2385
IST-MEL1 GDSC1 5.8709 8.0148 2.6434 0.8929
HMV-II GDSC1 6.1102 8.1239 2.6985 0.5537
Hs 934.T CTRP2 6.3161 7.6413 5.4595 1.9811
Hs 940.T GDSC1; CTRP2 6.5445 8.3221 5.2906 2.3233
RVH-421 GDSC1; CTRP2 6.632 10.949 4.0629 7.2567
COLO 829 GDSC1; CTRP2 6.7748 11.4861 3.9057 7.6655
A-388 GDSC1 6.7816 8.7916 2.7113 0.2672
UACC-62 GDSC1; CTRP2 6.9299 9.6324 4.9239 3.2498
IGR-37 GDSC1; CTRP2 7.0128 10.2341 4.6914 4.0672
WM88 CTRP2 7.0748 9.8881 4.8985 3.1529
A2058 GDSC1; CTRP2 7.1385 8.7976 5.4372 1.0609
Hs 294T CTRP2 7.2161 9.514 5.1615 1.967
Hs 839.T CTRP2 7.3301 11.1258 4.4788 4.4726
RPMI-7951 GDSC1; CTRP2 7.3659 8.9804 5.4766 0.7499
Hs 895.T CTRP2 7.502 11.8899 4.229 5.2299
SK-MEL-28 GDSC1; CTRP2 7.5318 13.2924 3.5727 7.8135
IGR-39 CTRP2 7.5586 9.1078 5.5157 0.5187
Hs 688(A).T CTRP2 7.6689 9.4754 5.4194 0.7112
HMCB CTRP2 7.7792 8.7988 5.7172 0.0727
LOX-IMVI GDSC1; CTRP2 7.7836 12.1802 4.2766 4.6649
Hs 936.T CTRP2 7.795 8.7851 5.7274 0.0611
SK-MEL-30 GDSC1; CTRP2 7.8244 13.1276 3.8539 6.27
IGR-1 GDSC1; CTRP2 7.8737 14.9483 3.0095 9.5144
G-361 GDSC1; CTRP2 7.9019 9.3323 5.5746 0.2431
IPC-298 GDSC1; CTRP2 7.9394 9.0902 5.6744 0.0924
K029AX CTRP2 7.9999 9.3019 5.6228 0.143
WM1799 CTRP2 8.0827 9.3878 5.6231 0.126
Hs 852.T CTRP2 8.153 9.5671 5.5862 0.159
WM793 GDSC1; CTRP2 8.2393 9.5294 5.6305 0.092
A-375 GDSC1; CTRP2 8.2649 9.7031 5.5798 0.1442
Mel JuSo GDSC1; CTRP2 8.2671 10.5084 5.2812 0.7285
MDA-MB-435S CTRP2 8.2783 9.3934 5.6895 0.0412
A101D GDSC1; CTRP2 8.2859 15.2992 3.1255 8.4626
COLO 800 GDSC1; CTRP2 8.5578 10.3176 5.4721 0.2265
Hs 944.T CTRP2 8.6749 10.7516 5.3605 0.3779
⏷ Show the Full List of 75 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-12 GDSC1 1.7444 4.3207 1.2644 23.3888
OACM5.1 C GDSC1 3.0525 8.1457 0.7039 21.0151
ESO-26 GDSC1 4.1747 8.0041 1.674 10.442
KYSE-50 GDSC1 4.3537 12.3258 -0.3269 21.9811
KYAE-1 GDSC1 4.4747 10.1343 0.8481 15.1587
KYSE-220 GDSC1 4.9032 10.134 1.1538 11.9671
FLO-1 GDSC1 5.8191 15.3616 -0.7384 19.7167
SK-GT-4 GDSC1 5.9534 8.5495 2.4734 1.5526
HCE-4 GDSC1 6.2251 14.6695 -0.1252 15.8799
OACP4 C GDSC1 6.2371 9.5679 2.1961 2.6257
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 4.16 10.0405 0.658 17.3162
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-10 GDSC1 -0.3374 1.4467 -0.3544 46.2255
GOTO GDSC1 1.0785 2.9674 0.9649 29.1903
IMR-32 CTRP2 1.6683 2.0806 1.6683 29.1541
SJNB-14 GDSC1 1.6684 4.2197 1.223 24.0824
CHP-134 GDSC1 1.9011 2.8738 1.8692 18.3912
MHH-NB-11 GDSC1; CTRP2 1.9241 3.4645 1.9202 27.463
NB69 GDSC1 2.0201 3.5136 1.8522 17.8143
KP-N-YS GDSC1 2.1966 3.7606 1.9611 16.087
SiMa GDSC1 2.366 6.9456 0.6817 24.0884
NH-6 CTRP2 2.4513 3.2603 2.4513 23.9376
IMR-5 GDSC1 2.4539 5.0769 1.6633 16.984
NB(TU)1 GDSC1 2.486 7.8603 0.3433 25.4982
SK-N-BE(2) CTRP2 2.6396 3.321 2.6396 22.6831
SJNB-12 GDSC1 2.7315 3.6957 2.5589 8.9924
GI-ME-N GDSC1 2.8409 4.0628 2.5165 8.7595
SK-N-MC-IXC GDSC1 3.1552 3.7626 2.9683 3.8739
Kelly GDSC1; CTRP2 3.1601 4.1033 3.1591 19.2189
LA-N-6 GDSC1 3.1972 4.1461 2.8219 4.8266
SJNB-17 GDSC1 3.2832 4.9802 2.4826 7.1575
NH-12 GDSC1 3.6086 5.6907 2.392 6.7352
KP-N-YN GDSC1 4.048 9.3337 0.9226 16.0287
CHP-212 GDSC1; CTRP2 4.1674 7.2353 3.5814 14.6594
SJNB-7 GDSC1 4.6486 13.2979 -0.583 22.2521
SK-N-BE(2)-M17 GDSC1 5.4446 7.0633 2.8242 0.5255
SJNB-6 GDSC1 5.5759 7.1425 2.8463 0.3876
TGW GDSC1 5.7417 7.113 2.9168 0.1688
SJNB-13 GDSC1 5.8247 7.5264 2.8035 0.3916
SJNB-5 GDSC1 5.9193 7.546 2.8315 0.2858
SK-N-AS GDSC1; CTRP2 6.1463 9.0121 4.6446 5.6898
SK-N-DZ GDSC1; CTRP2 6.9432 10.4276 4.5492 4.7472
SK-N-FI GDSC1; CTRP2 7.8733 13.0122 3.9414 5.8585
KP-N-SI9s CTRP2 8.0979 9.8213 5.4726 0.3679
SK-N-SH GDSC1; CTRP2 8.6126 10.3555 5.4791 0.2035
NB1 GDSC1; CTRP2 9.583 16.2487 3.5025 5.4355
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; CTRP2 4.7739 8.5885 3.6038 13.0024
SNU-478 CTRP2 6.9567 10.8644 4.3459 5.5579
HuH-28 CTRP2 7.0548 9.0894 5.2588 1.7863
SNU-308 CTRP2 7.5019 9.168 5.4653 0.6897
SNU-869 CTRP2 7.9043 11.0518 4.8682 2.3034
SNU-1079 CTRP2 8.3679 10.2462 5.4241 0.3641
SNU-1196 CTRP2 13.5597 26.6945 1.1059 9.0604
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1599 GDSC1 1.6361 2.7206 1.6067 21.6866
MRK-nu-1 GDSC1 1.8616 3.6786 1.6269 20.2486
DU4475 GDSC1; CTRP2 1.9026 3.3455 1.9002 27.6014
COLO 824 GDSC1 2.032 6.184 0.7293 25.3898
Hs 578Bst CTRP2 2.3965 3.1498 2.3964 24.3032
HCC1187 GDSC1 2.6006 5.1456 1.7739 15.4863
HCC1500 GDSC1; CTRP2 3.0671 7.5449 2.2902 22.631
BT-483 GDSC1 3.1205 4.5207 2.5675 7.1293
EFM-19 GDSC1 3.4657 5.6726 2.2879 8.0327
UACC-893 GDSC1 3.6614 5.6285 2.4632 6.01
HCC1569 GDSC1 3.6937 6.9684 1.823 10.8539
OCUB-M GDSC1 3.7255 7.3061 1.6799 11.8221
HCC2157 GDSC1 3.9326 6.2083 2.3773 5.8625
MDA-MB-175-VII GDSC1 4.1783 5.963 2.6575 3.1471
MDA-MB-157 GDSC1; CTRP2 4.2089 6.0644 4.0357 12.8349
Evsa-T GDSC1 4.3661 8.6936 1.4751 11.3006
MDA-MB-330 GDSC1 4.4762 11.7553 0.0495 19.7337
HCC1428 GDSC1; CTRP2 4.5072 6.2828 4.2961 10.9898
HMC-1-8 CTRP2 4.6534 8.5898 2.9362 10.3286
BT-20 GDSC1; CTRP2 4.6952 6.3133 4.4906 9.7174
MDA-MB-453 GDSC1; CTRP2 5.1127 10.8733 2.8154 15.4038
CAL-51 GDSC1; CTRP2 5.2057 11.9087 2.387 16.8782
AU565 GDSC1; CTRP2 5.3 9.7874 3.5214 12.1225
MDA-MB-468 GDSC1; CTRP2 5.567 10.6208 3.3471 12.2665
T-47D GDSC1; CTRP2 5.872 10.6895 3.5767 10.6935
EFM-192A GDSC1 5.8767 7.1733 2.943 0.1023
MDA-MB-415 GDSC1 6.0025 13.9602 0.0644 15.4633
HCC70 GDSC1 6.1972 16.5415 -1.0452 20.0654
YMB-1-E GDSC1 6.1978 13.659 0.3368 13.5655
ZR-75-30 GDSC1; CTRP2 6.3555 9.103 4.766 4.8023
HCC2218 GDSC1; CTRP2 6.4769 15.3999 1.722 16.7537
KPL-1 CTRP2 6.5084 8.3199 5.2663 2.4762
MDA-MB-436 GDSC1 6.6807 15.2954 -0.1223 14.816
HCC1954 GDSC1; CTRP2 7.09 9.8189 4.0693 1.5616
HCC1806 GDSC1; CTRP2 7.092 8.9464 4.4229 0.5101
UACC-812 GDSC1; CTRP2 7.2441 12.2893 3.8565 7.1101
CAL-120 GDSC1; CTRP2 7.38 9.6848 5.1799 1.7248
MDA-MB-361 GDSC1; CTRP2 7.3966 9.2026 5.399 0.9662
MCF-7 GDSC1; CTRP2 7.425 16.0639 1.3704 11.792
ZR-75-1 CTRP2 7.6423 9.1876 5.5216 0.4597
BT-474 GDSC1; CTRP2 7.9448 9.302 5.6022 0.1855
HCC1419 GDSC1; CTRP2 7.9667 9.2215 5.6388 0.1291
CAMA-1 GDSC1; CTRP2 7.9722 17.1166 1.2395 11.4395
Hs 578T GDSC1; CTRP2 7.9995 9.7892 5.4437 0.4711
MFM-223 GDSC1 8.0483 19.3797 -1.1643 16.53
SK-BR-3 CTRP2 8.1832 10.0416 5.4251 0.4324
CAL-148 GDSC1; CTRP2 8.2028 14.2777 3.5578 6.9095
BT-549 GDSC1; CTRP2 8.2452 9.8173 5.5322 0.215
HCC1937 GDSC1; CTRP2 8.2618 12.2491 4.5371 3.1213
JIMT-1 CTRP2 8.4134 22.9289 -0.514 20.2581
HDQ-P1 GDSC1; CTRP2 8.5298 10.2148 5.498 0.1961
HCC1143 CTRP2 8.5704 10.683 5.3438 0.447
HCC202 GDSC1; CTRP2 8.5827 10.7858 5.3103 0.5113
HCC38 GDSC1; CTRP2 8.6122 10.168 5.5442 0.1239
CAL-85-1 GDSC1; CTRP2 8.6638 10.5809 5.4182 0.2818
MDA-MB-231 GDSC1; CTRP2 10.0771 20.4616 1.8558 10.6189
HCC1395 GDSC1; CTRP2 10.1163 19.4572 2.3515 8.8821
BT 416 CTRP2 0.2135 3.6013 0.1448 39.0509
BT 231 CTRP2 2.294 3.3876 2.2935 24.9873
BT 504 CTRP2 2.3482 2.9008 2.3482 24.6244
BT 239 CTRP2 2.3505 5.8815 2.0564 25.6242
BT 286 CTRP2 2.3748 2.9942 2.3748 24.4473
BT 330 CTRP2 2.4293 2.9406 2.4293 24.0846
BT 145 CTRP2 2.4555 2.9763 2.4555 23.9099
BT 440 CTRP2 2.4695 2.9369 2.4695 23.8168
BT 428 CTRP2 2.4708 3.1048 2.4708 23.8079
BT 248 CTRP2 2.4844 3.0329 2.4844 23.7169
BT 245 CTRP2 2.4845 3.2339 2.4845 23.7165
BT 228 CTRP2 2.4866 2.8924 2.4866 23.7026
BT 482 CTRP2 2.5721 3.0468 2.5721 23.1326
BT 271 CTRP2 2.575 3.0422 2.575 23.1138
BT 139 CTRP2 2.5855 3.876 2.5823 23.0543
BT 187 CTRP2 2.5892 3.0352 2.5892 23.0191
BT 333 CTRP2 2.6136 3.0383 2.6136 22.8567
BT 179 CTRP2 2.6383 2.9893 2.6383 22.6917
BT 498 CTRP2 2.7466 3.8346 2.7454 21.9744
BT 422 CTRP2 2.7502 3.7152 2.7498 21.9478
BT 340 CTRP2 2.8359 3.3721 2.8359 21.3755
BT 131 CTRP2 2.8432 3.7582 2.8428 21.3281
BT 172 CTRP2 2.8913 4.1298 2.8871 21.0202
BT 216 CTRP2 2.8968 3.594 2.8968 20.97
BT 444 CTRP2 2.9451 3.7827 2.9449 20.6486
BT147 CTRP2 3.1096 4.0658 3.1086 19.5555
BT 232 CTRP2 3.1261 4.3908 3.1189 19.4659
BT 320 CTRP2 3.3542 4.0035 3.3541 17.9226
BT 359 CTRP2 3.6578 4.6784 3.6523 15.9182
BT 328 CTRP2 3.8535 4.6675 3.8515 14.6027
BT 159 CTRP2 7.2516 9.2856 5.2849 1.481
BT 224 CTRP2 7.9109 9.0506 5.6778 0.0933
BT 112 CTRP2 8.1855 10.0069 5.4391 0.4022
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.7963 8.9839 5.6593 0.1382
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YH-13 GDSC1; CTRP2 2.584 4.018 2.5775 23.0752
AM-38 GDSC1 2.9773 9.5432 -0.0585 25.5267
D283 Med GDSC1; CTRP2 3.2157 4.9445 3.1736 18.9873
PFSK-1 GDSC1 3.2226 5.3418 2.2499 9.2166
SW1783 GDSC1 3.2296 9.2666 0.2949 22.7031
D-336MG GDSC1 3.8836 9.7409 0.592 18.6303
Daoy GDSC1; CTRP2 4.1045 6.8432 3.6658 14.513
GB-1 GDSC1; CTRP2 4.5077 8.4772 3.3921 14.5117
SK-MG-1 GDSC1 4.8111 7.1213 2.5032 2.9376
D-502MG GDSC1 4.9634 8.8756 1.7933 7.4752
SF268 GDSC1; CTRP2 5.0336 8.2281 4.0274 10.6541
KINGS-1 GDSC1 5.0835 8.1424 2.2032 4.4037
8-MG-BA GDSC1; CTRP2 5.0962 8.7603 3.8333 11.2995
SF539 GDSC1; CTRP2 5.0966 10.2556 3.1048 14.277
GI-1 GDSC1 5.097 12.3685 0.2055 17.0841
LNZTA3WT4 GDSC1 5.1478 12.8907 -0.013 18.0883
MOG-G-CCM GDSC1 5.2056 8.9893 1.891 6.2554
SW1088 GDSC1; CTRP2 5.3058 10.2462 3.3001 13.0185
D-423MG GDSC1 5.3264 7.9561 2.4164 2.6338
MOG-G-UVW GDSC1 5.4022 11.0791 1.0378 11.4112
D-566MG GDSC1 5.5068 11.424 0.943 11.739
D-542MG GDSC1 5.5455 11.9705 0.7085 13.0521
Onda 10 GDSC1 5.5805 7.6743 2.6505 1.1013
LN-405 GDSC1 5.6746 12.695 0.449 14.2156
D-247MG GDSC1 5.6852 16.4658 -1.3735 22.616
D-263MG GDSC1 5.7213 13.7056 -0.0047 16.5179
M059J GDSC1 5.8241 13.5004 0.1642 15.3852
SNB-75 GDSC1; CTRP2 5.9509 8.2682 4.8536 5.1887
KNS-81-FD GDSC1 5.9677 12.9695 0.5128 13.1415
KS-1 [Human Krukenberg tumour] GDSC1 6.0156 11.9128 1.0388 9.9661
SF126 GDSC1; CTRP2 6.0272 9.8294 4.1376 8.0464
D-392MG GDSC1 6.0387 10.4508 1.7163 5.7367
KALS-1 GDSC1; CTRP2 6.073 8.1426 5.019 4.2551
Onda 11 GDSC1 6.1178 13.5824 0.3208 13.8389
T98G GDSC1; CTRP2 6.2109 11.1313 3.6383 9.7798
KNS-42 GDSC1; CTRP2 6.3331 9.9606 4.3214 6.7029
LN-18 GDSC1; CTRP2 6.3924 13.521 2.592 13.6647
SNU-1105 CTRP2 6.6031 8.8708 4.2209 1.4702
H4 GDSC1 6.7319 15.5937 -0.2299 15.2208
YKG-1 GDSC1; CTRP2 6.8185 12.917 3.23 10.3552
U-87MG ATCC GDSC1; CTRP2 7.0318 17.9519 0.1628 16.809
KNS-81 CTRP2 7.0356 8.7641 5.3948 1.3087
Becker GDSC1; CTRP2 7.1652 15.5634 2.1836 13.8182
NMC-G1 GDSC1; CTRP2 7.2508 11.1015 4.4369 4.7514
KNS-60 CTRP2 7.4077 8.565 5.6599 0.2542
KG-1-C CTRP2 7.4407 10.6504 4.7749 3.1662
CAS-1 GDSC1; CTRP2 7.5416 8.8741 5.5989 0.3283
CCF-STTG1 CTRP2 7.5956 8.593 5.7224 0.0976
SNU-626 CTRP2 7.6751 9.064 5.5827 0.3077
GMS-10 CTRP2 7.7649 8.8519 5.6939 0.1002
SF295 GDSC1; CTRP2 7.8028 11.8109 4.4616 3.9252
ONS-76 GDSC1; CTRP2 7.8039 12.4977 4.1399 5.1726
SNU-466 CTRP2 7.8147 8.7715 5.7388 0.0494
SNU-738 CTRP2 7.8342 9.43 5.5108 0.3949
TM-31 CTRP2 7.9432 9.1589 5.652 0.1173
SNU-201 CTRP2 7.9715 9.5734 5.5136 0.3337
M059K CTRP2 7.9779 9.2144 5.6453 0.1188
GOS-3 CTRP2 8.1755 9.3986 5.6525 0.0798
SNU-489 CTRP2 8.3554 18.2501 1.744 13.4401
DK-MG GDSC1; CTRP2 8.5013 17.2257 2.3453 11.075
LN-229 GDSC1; CTRP2 8.6558 14.0785 3.9387 4.8861
Hs 683 GDSC1; CTRP2 8.8758 17.75 2.35 10.5168
A-172 GDSC1; CTRP2 8.971 17.1181 2.7155 9.0544
42-MG-BA GDSC1; CTRP2 10.0911 19.8573 2.1488 9.609
U-251MG GDSC1; CTRP2 10.2357 21.3171 1.5548 11.4108
DBTRG-05MG GDSC1; CTRP2 10.2769 20.5105 1.961 10.0132
GaMG GDSC1; CTRP2 10.7108 21.323 1.8554 9.8335
U-118MG GDSC1; CTRP2 10.8779 23.6002 0.8939 12.6714
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 2.4727 4.1453 2.1023 13.6357
TGBC24TKB GDSC1 3.8437 11.7662 -0.4498 24.2062
TGBC1TKB GDSC1 7.52 19.8335 -1.724 19.6884
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 1.1052 5.5387 0.601 29.9307
AN3-CA GDSC1; CTRP2 2.0181 3.3507 2.0165 26.8292
HEC-1-A CTRP2 3.7607 6.2996 3.4781 16.2128
HEC-59 CTRP2 4.3279 8.1662 2.8524 11.4542
KLE GDSC1; CTRP2 4.7402 6.2844 4.549 9.3689
JHUEM-1 CTRP2 5.3132 9.0254 3.9079 10.4964
MFE-296 GDSC1; CTRP2 5.3479 10.2176 3.3523 12.7129
HEC-151 CTRP2 5.6649 9.8145 3.8344 10.0433
MFE-280 GDSC1 6.1173 11.9021 1.1063 9.3375
ESS-1 GDSC1; CTRP2 6.2396 9.2774 4.5876 5.757
HEC-265 CTRP2 6.4772 8.817 5.0002 3.6213
EFE-184 CTRP2 6.5376 9.4486 4.7338 4.627
MFE-319 GDSC1; CTRP2 6.6387 9.223 4.9191 3.6991
HEC-6 CTRP2 7.6125 8.9654 5.594 0.3093
JHUEM-3 CTRP2 7.8726 9.6249 5.4523 0.5113
HEC-251 CTRP2 8.1269 9.3943 5.6368 0.1025
EN GDSC1; CTRP2 8.2217 13.14 4.1053 4.7752
RL95-2 GDSC1; CTRP2 8.4359 10.0223 5.5309 0.1721
HEC-108 CTRP2 8.7576 15.623 2.4355 5.8556
HEC-50B CTRP2 8.9008 10.6907 5.4676 0.1604
HEC-1-B CTRP2 10.0562 23.797 -0.5561 14.463
Ishikawa (Heraklio) 02 ER- CTRP2 10.1937 24.1055 -0.6121 14.4451
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 1.8277 6.7531 1.2312 56.7139
SW156 GDSC1 2.7713 3.6232 2.6292 8.2793
KTCTL-21 GDSC1 2.7799 4.9183 2.0549 12.5533
KTCTL-195 GDSC1 2.9668 3.8859 2.7236 6.6042
NCC021 GDSC1 3.102 4.0431 2.7832 5.5319
UO-31 GDSC1; CTRP2 3.4956 7.3549 2.8205 19.4342
A-704 GDSC1 3.556 5.3496 2.5206 5.8999
SW13 GDSC1 4.2985 8.2365 1.6497 10.2528
TK-10 GDSC1 4.5 7.0825 2.338 4.7035
786-O GDSC1; CTRP2 4.7772 10.7199 2.5817 17.0893
VMRC-RCZ GDSC1; CTRP2 4.7795 6.0634 4.6587 8.8499
LB996-RCC GDSC1 4.7948 7.8391 2.17 5.2301
KTCTL-1M GDSC1 5.1328 12.6306 0.1032 17.5278
SN12C GDSC1 5.6265 13.9392 -0.1835 17.6551
BB65-RCC GDSC1 5.6899 16.4435 -1.3591 22.55
LB2241-RCC GDSC1 5.717 13.9027 -0.1028 17.0229
KTCTL-140 GDSC1 5.7517 13.0844 0.3146 14.7625
KTCTL-26A GDSC1 5.7853 15.3087 -0.7366 19.7944
RXF 393L GDSC1 5.8243 8.442 2.4576 1.7648
KTCTL-13 GDSC1 6.136 15.1801 -0.4302 17.5496
LB1047-RCC GDSC1 6.4393 19.8691 -2.4932 24.5485
VMRC-RCW GDSC1; CTRP2 6.501 13.0177 2.9306 12.1263
TUHR4TKB CTRP2 6.6938 13.7319 2.7275 12.5779
KMRC-2 CTRP2 6.9282 11.2761 4.1236 6.5155
HA7-RCC GDSC1 6.9967 19.4533 -1.8976 21.4036
CAL-54 GDSC1; CTRP2 7.1107 12.725 3.5458 8.5838
A-498 GDSC1; CTRP2 7.1528 12.0129 3.9259 6.9696
RCC10RGB GDSC1; CTRP2 7.2412 9.5263 5.1708 1.9045
SNU-1272 CTRP2 7.3008 9.0819 5.4008 1.0395
BFTC-909 GDSC1; CTRP2 7.3015 9.9819 4.9985 2.48
769-P GDSC1; CTRP2 7.3686 8.7781 4.5913 0.1206
TUHR10TKB CTRP2 7.4148 8.9569 5.5098 0.6204
KMRC-1 GDSC1; CTRP2 7.7965 12.8355 3.9746 5.8325
KMRC-3 CTRP2 8.1981 14.9576 3.2298 8.1856
Caki-2 CTRP2 8.2829 9.5447 5.6405 0.0768
ACHN GDSC1; CTRP2 10.1402 23.5485 0.4258 15.046
OS-RC-2 GDSC1; CTRP2 11.5875 22.4889 1.8537 8.8352
KMRC-20 GDSC1; CTRP2 12.6865 26.2619 0.7884 10.8669
Caki-1 GDSC1; CTRP2 14.5262 30.6642 -0.1212 11.4456
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KM12 GDSC1; CTRP2 1.0331 9.7778 -0.7565 37.9446
COLO 320 CTRP2 2.4899 3.6932 2.4882 23.6861
SNU-175 GDSC1 2.5204 6.3721 1.1054 20.6639
SW48 GDSC1; CTRP2 3.2459 7.27 2.5858 21.0243
LS123 GDSC1; CTRP2 3.7644 5.3768 3.7016 15.4034
SNU-C1 GDSC1; CTRP2 3.7901 5.271 3.7442 15.174
NCI-H747 GDSC1; CTRP2 4.2599 6.9577 3.7889 13.6069
CL-11 GDSC1; CTRP2 4.542 7.3843 3.9131 12.3562
SW948 GDSC1; CTRP2 4.5863 6.2621 4.3887 10.4147
T84 GDSC1; CTRP2 4.6571 7.4261 4.0144 11.6531
NCI-H716 GDSC1; CTRP2 4.6933 10.2597 2.7267 16.7159
SNU-1040 GDSC1 4.8079 7.8124 2.1902 5.0603
SNU-407 GDSC1; CTRP2 4.9392 10.0382 3.0654 14.7935
RKO GDSC1; CTRP2 4.9764 10.0882 3.0756 14.667
SNU-C5 GDSC1; CTRP2 4.9979 8.7239 3.7567 11.8435
GP5d GDSC1 5.2043 12.554 0.1916 16.8614
HCC2998 GDSC1 5.4011 8.5631 2.1946 3.874
SW1116 GDSC1 5.5033 7.2135 2.7923 0.5979
SNU-81 GDSC1 5.533 7.1043 2.8436 0.416
SW1463 GDSC1 5.6505 7.2967 2.8195 0.4282
LS180 GDSC1; CTRP2 5.7329 11.2491 2.4955 10.0803
HT115 GDSC1; CTRP2 5.7802 11.4373 3.1247 12.7363
COLO 320HSR GDSC1 5.812 7.7451 2.7197 0.6547
SW837 GDSC1 5.8604 7.8471 2.7015 0.687
SW620 GDSC1; CTRP2 6.0537 7.579 5.2849 3.1746
SNU-61 GDSC1; CTRP2 6.3029 9.2934 4.63 5.4645
HT-29 GDSC1; CTRP2 6.5145 7.5978 4.6903 0.1741
SW626 GDSC1 6.5578 8.618 2.6909 0.3792
LoVo GDSC1; CTRP2 6.7127 13.9854 2.6162 12.9783
HCC-56 CTRP2 6.7417 10.4545 4.39 5.7173
DLD-1 CTRP2 6.7855 8.7558 5.2454 2.1685
LS1034 GDSC1; CTRP2 6.9325 11.37 4.0806 6.6854
HCT 116 GDSC1; CTRP2 6.9563 8.402 4.5706 0.2501
CaR-1 GDSC1 7.0857 17.2001 -0.759 16.8383
OUMS-23 CTRP2 7.5031 19.4705 0.5049 18.8942
HT-55 GDSC1; CTRP2 7.5148 12.1073 4.1335 5.5929
HCT 15 GDSC1; CTRP2 7.516 11.05 4.6359 3.6093
C2BBe1 GDSC1; CTRP2 7.6207 10.2092 5.0826 1.8287
NCI-H508 CTRP2 7.6561 9.4206 5.4355 0.6747
SNU-1033 CTRP2 7.7391 11.8927 4.3831 4.3074
SNU-C4 CTRP2 7.7395 8.8538 5.684 0.1174
MDST8 GDSC1; CTRP2 7.8459 9.1441 5.621 0.1823
COLO205 GDSC1; CTRP2 7.8745 17.8827 1.5726 14.8029
LS513 GDSC1; CTRP2 7.9243 9.233 5.619 0.1655
LS411N GDSC1; CTRP2 7.925 9.8053 5.405 0.6004
SW1417 GDSC1; CTRP2 8.0316 10.3392 5.2401 0.9824
RCM-1 [Human ESC] GDSC1; CTRP2 8.0589 9.2177 5.6731 0.0763
SK-CO-1 CTRP2 8.0947 10.0424 5.3872 0.5573
SNU-C2B GDSC1 8.2576 19.9936 -1.3188 16.7263
CCK-81 GDSC1; CTRP2 8.4795 15.9124 2.9626 8.8099
COLO 678 GDSC1; CTRP2 8.5021 10.1194 5.5212 0.171
SNU-C2A CTRP2 8.5113 10.8194 4.2971 0.2715
CW-2 GDSC1; CTRP2 8.8429 10.7921 5.4108 0.2469
HCT 8 CTRP2 9.3293 16.0547 3.4397 5.9454
COLO201 CTRP2 11.8769 23.3563 1.6308 9.2213
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 5.1392 12.4709 0.1857 17.0727
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 2.6067 4.1518 2.5962 22.9373
JHH-7 GDSC1 3.0564 3.7419 2.8792 5.0098
JHH-4 GDSC1; CTRP2 3.1884 7.4222 2.4668 21.6311
JHH-5 CTRP2 3.5603 6.0879 3.3214 17.3864
Huh-7 GDSC1 4.0377 9.932 0.6175 17.96
HuH-6 CTRP2 4.1624 11.6658 1.5442 22.4103
SNU-886 CTRP2 4.5158 7.8489 3.6842 18.1442
PLC/PRF/5 CTRP2 4.7046 7.2856 4.124 11.0967
SNU-878 CTRP2 5.0023 8.8181 3.7159 12
Hep-G2/C3A GDSC1 5.1781 6.5751 2.8976 0.4401
JHH-2 GDSC1; CTRP2 5.2833 7.5843 4.5748 7.8222
Li-7 CTRP2 5.3592 9.226 3.8518 10.6264
SNU-423 GDSC1; CTRP2 5.7087 8.9829 4.2868 8.0617
HLE GDSC1 5.8528 7.8162 2.7098 0.6632
JHH-6 GDSC1; CTRP2 5.9959 6.5661 5.7421 1.3675
Hep 3B2.1-7 GDSC1; CTRP2 6.0845 13.285 1.7555 12.5589
JHH-1 GDSC1; CTRP2 6.2149 9.9067 4.2534 7.2039
SNU-761 CTRP2 6.2666 11.272 3.6134 9.7785
SNU-449 GDSC1; CTRP2 6.2739 9.396 4.5558 5.8275
HuH-1 GDSC1; CTRP2 7.6979 8.9564 5.6316 0.207
SK-HEP-1 GDSC1; CTRP2 7.7006 9.3637 5.4785 0.5358
Hep-G2 CTRP2 7.7455 8.9102 5.6664 0.1398
SNU-475 GDSC1; CTRP2 7.9469 10.3537 5.1927 1.1836
SNU-398 GDSC1; CTRP2 8.0304 17.2862 1.9805 13.1174
SNU-387 GDSC1; CTRP2 8.3498 10.1811 5.4409 0.3388
HLF CTRP2 11.3041 33.3899 -3.5314 22.7944
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 212 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1385 CTRP2 0.5259 18.0793 -5.021 44.2273
EBC-1 GDSC1; CTRP2 1.8916 6.7417 1.3043 29.6454
UMC-11 GDSC1 2.0194 3.7558 1.7715 18.3775
NCI-H1581 GDSC1; CTRP2 2.0944 4.54 2.0321 26.5254
NCI-H1341 GDSC1; CTRP2 2.1723 2.916 2.1723 25.7966
NCI-H211 GDSC1; CTRP2 2.269 3.4978 2.2676 25.1569
NCI-H1694 GDSC1; CTRP2 2.3423 3.6406 2.3401 24.6712
NCI-H1155 GDSC1; CTRP2 2.4055 3.2488 2.4054 24.2432
NCI-H2106 CTRP2 2.438 4.1107 2.4248 24.0703
NCI-H290 GDSC1 2.7081 3.9302 2.4384 9.9884
NCI-H524 GDSC1; CTRP2 2.7269 3.9475 2.7241 22.1112
Lu-135 GDSC1 2.7432 6.1576 1.4167 17.5035
LK-2 GDSC1 2.7589 8.5902 0.2261 24.9581
LB647-SCLC GDSC1 2.8578 4.1634 2.4876 8.8973
NCI-H847 GDSC1 2.9417 5.1192 2.1092 11.4395
NCI-H446 GDSC1; CTRP2 3.0138 4.2727 3.0081 20.2094
NCI-H2171 GDSC1; CTRP2 3.0684 5.0666 3.0019 20.0522
HCC44 GDSC1; CTRP2 3.0747 6.3485 2.7156 21.0494
NCI-H720 GDSC1 3.1424 5.5246 2.0891 10.7847
NCI-H510A GDSC1 3.1648 6.9625 1.3911 15.97
IST-SL1 GDSC1 3.293 6.7571 1.6028 13.9306
HCC15 GDSC1; CTRP2 3.3297 5.6332 3.1831 18.5908
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 3.4442 6.8617 2.9479 19.1038
COR-L321 GDSC1 3.4676 11.5727 -0.6596 26.4195
A-427 GDSC1 3.5776 7.2972 1.567 13.165
Calu-3 GDSC1; CTRP2 3.6054 5.4064 3.5258 16.5206
NCI-H1436 GDSC1 3.6565 5.4111 2.567 5.2166
DV-90 CTRP2 3.6778 7.4579 2.9741 18.3411
SBC-3 GDSC1 3.6902 6.9505 1.8292 10.8182
NCI-H2081 GDSC1; CTRP2 3.7129 6.8274 3.2501 17.1987
NCI-H526 GDSC1; CTRP2 3.7477 5.4405 3.6732 15.5549
NCI-H835 GDSC1 3.7545 12.2345 -0.7556 25.828
NCI-H810 GDSC1; CTRP2 3.8295 5.8231 3.6838 15.2609
NCI-H69 GDSC1; CTRP2 3.8331 8.4251 2.7313 18.85
NCI-H1573 GDSC1; CTRP2 4.0127 9.6868 2.3407 19.8787
T3M-10 CTRP2 4.0495 5.6375 3.9634 13.5857
Ms-1 GDSC1 4.0841 8.9796 1.1257 14.5757
NCI-H1563 GDSC1; CTRP2 4.1187 5.8571 3.9908 13.2725
SW1271 GDSC1; CTRP2 4.1741 7.2713 3.5741 14.6691
NCI-H1770 GDSC1 4.177 6.1785 2.5563 3.8802
DMS 53 GDSC1; CTRP2 4.2195 7.1924 3.6537 14.2375
Lu-165 GDSC1 4.2373 8.5124 1.4704 11.7175
COR-L303 GDSC1 4.2633 9.3099 1.0973 14.1992
SBC-1 GDSC1 4.2887 7.4071 2.0453 7.3765
HCC1588 CTRP2 4.2952 7.6141 3.092 10.4732
LK2 CTRP2 4.3294 12.3338 1.3768 22.5784
COLO 668 GDSC1; CTRP2 4.4313 6.8429 4.0159 12.2606
NCI-H23 GDSC1; CTRP2 4.4391 7.6402 3.6967 13.4783
NCI-H1651 GDSC1 4.442 8.1413 1.7969 8.7813
NCI-H345 GDSC1 4.4605 5.7718 2.8973 1.0889
DMS 454 CTRP2 4.5101 9.5172 2.9078 16.4377
LC-2/ad GDSC1 4.5344 11.4627 0.238 18.5514
Calu-1 CTRP2 4.5406 8.2516 3.5283 13.8849
NCI-H187 GDSC1 4.544 10.9624 0.4919 17.0962
LOU-NH91 GDSC1 4.5505 11.0795 0.439 17.3805
NCI-H1304 GDSC1 4.5662 10.0435 0.9595 14.1794
COR-L311 GDSC1 4.5694 8.1376 1.8853 7.8025
NCI-H2141 GDSC1; CTRP2 4.6168 7.6373 3.8809 12.2859
IST-SL2 GDSC1 4.627 12.8139 -0.3599 21.2986
NCI-H1781 GDSC1 4.6638 11.6614 0.2365 18.1682
NCI-H322M GDSC1 4.6755 7.3334 2.3298 4.3734
NCI-H841 GDSC1; CTRP2 4.6842 10.2387 2.7284 16.7308
COR-L23 GDSC1 4.6987 6.6459 2.6495 2.2009
NCI-H1975 GDSC1 4.7462 7.2893 2.3917 3.8014
CPC-N GDSC1 4.75 7.3489 2.367 3.9615
NCI-H2029 GDSC1; CTRP2 4.7584 6.8055 4.3788 9.9601
Lu-139 GDSC1 4.7695 12.6372 -0.1656 19.9384
NCI-H2135 GDSC1 4.7894 6.3904 2.8018 1.1923
NCI-H1688 GDSC1 4.813 11.2038 0.5703 15.8428
LCLC-97TM1 GDSC1; CTRP2 4.8381 8.2944 3.8047 12.0326
NCI-H1693 CTRP2 4.8517 6.9799 4.4063 9.5986
NCI-H1703 GDSC1; CTRP2 4.8673 8.912 3.5412 13.0314
EPLC-272H GDSC1; CTRP2 4.8926 6.711 4.5585 8.8978
COR-L88 GDSC1 4.8939 8.2861 2.0244 6.0257
HCC1833 CTRP2 4.9829 8.3996 3.3153 7.9135
SBC-5 GDSC1; CTRP2 5.0289 7.2137 4.4895 8.8031
NCI-H1048 GDSC1 5.0875 9.9334 1.3744 10.0268
NCI-H1836 GDSC1 5.0939 12.119 0.3249 16.4419
NCI-H146 GDSC1 5.0976 7.6763 2.4166 2.9945
NCI-H1092 GDSC1; CTRP2 5.146 8.7104 3.9046 10.891
NCI-H2087 GDSC1; CTRP2 5.1746 8.9709 3.8053 11.2338
EMC-BAC-1 GDSC1 5.1992 13.1908 -0.1226 18.4992
NCI-H513 GDSC1 5.2094 10.0239 1.4113 9.478
VMRC-LCD CTRP2 5.2132 8.4771 4.081 10.0102
NCI-H1105 GDSC1; CTRP2 5.2353 9.6258 3.5416 12.1825
PC-14 GDSC1; CTRP2 5.2799 10.4127 3.1945 13.5064
NCI-H2803 GDSC1 5.337 11.2562 0.91 12.3691
NCI-H2810 GDSC1 5.3789 11.2595 0.9365 12.0993
HCC1171 CTRP2 5.3921 6.7472 5.0669 5.57
RERF-LC-MS GDSC1; CTRP2 5.3973 12.1121 2.4557 16.1975
ABC-1 GDSC1 5.4043 13.649 -0.1993 18.3188
NCI-H2373 GDSC1 5.4136 12.9207 0.161 16.459
NCI-H3122 GDSC1 5.4395 10.523 1.3246 9.4939
NCI-H2066 GDSC1 5.4559 7.5058 2.6616 1.1677
NCI-H1568 GDSC1; CTRP2 5.4718 9.7084 3.7158 10.9452
NCI-H2347 GDSC1 5.4734 8.879 2.0957 4.3742
NCI-H2591 GDSC1 5.4761 13.1563 0.0906 16.6638
NCI-H2369 GDSC1 5.4987 8.9605 2.0738 4.468
IA-LM GDSC1 5.528 6.9399 2.8999 0.2689
NCI-H209 GDSC1 5.5305 7.7006 2.6184 1.2949
PaCa-3 GDSC1 5.5324 9.4316 1.8832 5.6346
NCI-H2818 GDSC1 5.5467 12.7754 0.3235 15.2354
SK-MES-1 GDSC1; CTRP2 5.5554 8.4516 4.4124 7.8657
NCI-H64 GDSC1 5.5769 6.6405 3.0182 0.0612
NCI-H1339 CTRP2 5.5781 7.7465 4.7792 6.2921
RERF-LC-A1 CTRP2 5.603 10.3202 3.5284 11.4433
HCC4006 CTRP2 5.6296 6.182 5.5479 3.0573
NCI-H2795 GDSC1 5.6405 7.8722 2.5999 1.273
MOR/CPR CTRP2 5.6454 14.4292 0.843 16.9851
HCC2279 CTRP2 5.6501 9.039 4.207 8.5189
Lu-99A GDSC1 5.6957 9.5027 1.9441 4.9355
NCI-H2722 GDSC1 5.7079 7.7772 2.6654 0.931
NCI-H1944 GDSC1; CTRP2 5.7525 8.1733 4.7279 6.1243
NCI-H1876 GDSC1 5.8152 7.3782 2.852 0.2759
NCI-H1793 GDSC1; CTRP2 5.8832 7.3992 5.2283 3.7546
Lu-134-A GDSC1 5.9317 9.2884 2.1619 3.227
NCI-H3255 GDSC1 5.9699 15.5237 -0.711 19.2187
NCI-H596 GDSC1 6.0226 7.5285 2.8741 0.1733
NCI-H2869 GDSC1 6.0232 8.4798 2.5309 1.2296
NCI-H520 GDSC1; CTRP2 6.0353 9.3022 4.4079 6.8957
HCC2935 CTRP2 6.0363 9.1695 4.4751 6.6115
NCI-H2804 GDSC1 6.0418 13.5206 0.3001 14.1306
NCI-H1650 GDSC1; CTRP2 6.0464 9.4159 4.3603 7.0745
SW1573 GDSC1 6.0724 13.7049 0.2328 14.4165
NCI-H1437 GDSC1 6.1018 8.609 2.5149 1.2302
EMC-BAC-2 GDSC1 6.1128 8.1887 2.6761 0.6216
NCI-H1838 GDSC1; CTRP2 6.1262 9.527 4.3708 6.878
LCLC-103H GDSC1; CTRP2 6.1295 16.0881 0.3987 17.6453
RERF-LC-Sq1 GDSC1 6.1585 8.1552 2.7057 0.5085
NCI-H82 GDSC1 6.1659 14.0184 0.1456 14.6512
NCI-H2595 GDSC1 6.1916 13.3342 0.4859 12.7672
NCI-H2731 GDSC1 6.2252 13.5943 0.3851 13.2409
COR-L95 GDSC1; CTRP2 6.2503 9.2105 4.6295 5.5614
RERF-LC-KJ GDSC1 6.2542 14.5432 -0.0456 15.4164
NCI-H2110 GDSC1; CTRP2 6.3371 9.389 4.6094 5.49
NCI-H647 GDSC1; CTRP2 6.4131 9.6418 4.5429 5.6342
HCC33 GDSC1 6.4391 16.9468 -1.0731 19.6027
NCI-H1734 GDSC1; CTRP2 6.453 10.8857 3.9552 8.0175
NCI-H1648 GDSC1 6.4989 8.5297 2.7002 0.379
Lu-99 CTRP2 6.5356 11.4271 3.7506 8.7201
NCI-H1993 GDSC1 6.579 16.6899 -0.8537 18.3723
DMS 114 GDSC1; CTRP2 6.5998 12.5417 3.2462 10.6759
DMS 273 GDSC1; CTRP2 6.6622 11.2846 3.9197 7.7989
COR-L105 GDSC1; CTRP2 6.7033 9.746 4.7099 4.4585
NCI-H1184 CTRP2 6.8807 10.2299 4.601 4.6305
NCI-H2196 GDSC1; CTRP2 6.8925 11.2949 4.0881 6.7189
NCI-H196 GDSC1; CTRP2 6.9151 9.6325 4.9138 3.3111
NCI-H838 GDSC1; CTRP2 6.9697 10.6035 4.4824 4.9798
RERF-LC-Ad1 CTRP2 7.0207 7.9967 5.7125 0.3116
HOP-62 GDSC1; CTRP2 7.0233 15.7236 1.9944 14.7642
NCI-H2444 GDSC1; CTRP2 7.0613 11.4712 4.1247 6.3008
EKVX GDSC1; CTRP2 7.0916 14.3465 2.7305 11.8654
NCI-H1666 GDSC1; CTRP2 7.098 10.1432 4.7926 3.542
NCI-H358 GDSC1; CTRP2 7.1533 11.2576 4.2941 5.4703
BEN GDSC1; CTRP2 7.1934 8.1029 5.7448 0.1667
NCI-H460 GDSC1; CTRP2 7.1936 13.1886 3.3789 9.1229
NCI-H292 GDSC1; CTRP2 7.2069 14.4963 2.7438 11.6171
NCI-H2228 GDSC1; CTRP2 7.2795 11.0036 4.5033 4.4453
HCC2108 CTRP2 7.4847 13.2829 2.7379 6.2552
Sq-1 CTRP2 7.4963 11.875 4.2323 5.225
NCI-H2122 GDSC1; CTRP2 7.4973 9.6772 5.2482 1.3749
ChaGo-K-1 GDSC1; CTRP2 7.5031 10.8704 4.7117 3.3328
HCC827 GDSC1; CTRP2 7.528 10.8303 3.8651 1.8801
NCI-H1792 GDSC1; CTRP2 7.534 14.3566 3.0549 9.8648
NCI-H2461 GDSC1 7.6279 17.2295 -0.4261 14.2453
NCI-H1755 GDSC1; CTRP2 7.6567 10.0642 5.1659 1.5085
NCI-H650 GDSC1; CTRP2 7.6591 9.6627 4.3868 0.3599
HCC1195 CTRP2 7.6825 11.6965 4.439 4.1623
NCI-H2291 GDSC1; CTRP2 7.6865 10.2451 5.1031 1.6945
HCC1438 CTRP2 7.7142 13.7137 3.4964 7.8439
NCI-H2170 GDSC1; CTRP2 7.7443 9.9442 5.2627 1.1214
LC-1/sq-SF CTRP2 7.7487 8.7594 5.7199 0.0745
Calu-6 GDSC1; CTRP2 7.7561 12.3439 4.1814 5.073
LUDLU-1 CTRP2 7.8865 9.3294 5.5696 0.257
NCI-H2172 GDSC1; CTRP2 7.939 9.6271 5.4799 0.4172
SHP-77 GDSC1; CTRP2 8.0233 9.454 5.5776 0.2029
NCI-H889 CTRP2 8.0593 9.7162 5.4961 0.3358
NCI-H2126 CTRP2 8.0916 9.4116 5.6181 0.1304
NCI-H226 GDSC1; CTRP2 8.0918 13.8027 3.7101 6.4678
SK-LU-1 GDSC1; CTRP2 8.1039 15.3083 2.9962 9.2216
NCI-H2023 GDSC1; CTRP2 8.118 14.6139 3.3404 7.8711
NCI-H2030 GDSC1; CTRP2 8.156 13.8048 2.9052 4.7642
HCC95 CTRP2 8.1716 9.6158 5.576 0.1688
NCI-H1355 GDSC1; CTRP2 8.2128 17.2369 2.1362 12.271
NCI-H1435 GDSC1; CTRP2 8.3219 9.8016 5.5662 0.15
NCI-H2286 CTRP2 8.3461 9.685 5.6151 0.0918
HCC366 CTRP2 8.3484 9.9411 5.527 0.197
HOP-92 CTRP2 8.3585 23.4437 -0.81 21.1142
NCI-H2085 CTRP2 8.3919 10.2455 5.4339 0.3375
NCI-H1373 CTRP2 8.4193 11.4164 4.9843 1.4682
NCI-H2342 GDSC1; CTRP2 8.4492 10.254 5.4534 0.2853
NCI-H1869 GDSC1; CTRP2 8.4679 10.6648 5.308 0.5653
NCI-H522 GDSC1; CTRP2 8.4891 9.9813 5.5644 0.122
NCI-H1395 CTRP2 8.4945 11.4023 5.0271 1.2858
Lu-65 GDSC1; CTRP2 8.5093 14.0997 3.8387 5.4362
COLO 699 CTRP2 8.5424 17.4705 1.4487 9.8396
NCI-H2009 GDSC1; CTRP2 8.5573 10.212 5.5091 0.1753
NCI-H322 CTRP2 8.6177 13.8755 4.0088 4.6694
LXF 289 GDSC1; CTRP2 8.6428 15.6337 3.2039 7.6737
NCI-H1299 GDSC1; CTRP2 8.6568 10.4659 5.4566 0.225
RERF-LC-Ad2 CTRP2 8.691 9.9306 5.6507 0.0343
NCI-H441 GDSC1; CTRP2 8.7033 10.4418 5.4823 0.1799
NCI-H1915 GDSC1; CTRP2 8.7131 15.8349 3.1546 7.7663
HCC78 GDSC1; CTRP2 8.8736 10.464 5.5354 0.0958
NCI-H1623 GDSC1; CTRP2 8.9487 10.5942 5.5176 0.1022
CAL-12T GDSC1; CTRP2 8.9787 20.3206 0.3839 12.9885
NCI-H661 GDSC1; CTRP2 9.0235 10.7431 5.4933 0.1146
NCI-H727 GDSC1; CTRP2 9.8224 17.4924 3.0785 6.6793
NCI-H2405 GDSC1; CTRP2 9.8469 19.5344 2.144 9.9347
KNS-62 GDSC1; CTRP2 10.3038 17.5131 3.3502 5.2154
A-549 GDSC1; CTRP2 10.5714 18.0849 3.247 5.3
Hs 888.Lu CTRP2 6.193 10.0512 4.1635 7.622
⏷ Show the Full List of 212 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 4.7223 11.7228 0.2496 17.923
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 1.4154 8.1095 0.3093 34.1946
Yamato-SS CTRP2 2.8123 9.2572 1.3178 26.7893
G-401 GDSC1; CTRP2 2.275 5.3739 2.0925 25.7363
GCT GDSC1; CTRP2 2.7309 3.1627 2.7309 22.0749
SW872 GDSC1 2.851 3.5122 2.7556 6.9576
Hs 633.T GDSC1 2.8945 3.3959 2.841 6.1244
EW-8 GDSC1 2.9996 3.8735 2.7623 6.1576
Rh30 GDSC1 3.091 5.6576 1.9776 11.8522
A-204 GDSC1; CTRP2 3.2666 9.9936 1.4548 25.0495
SK-LMS-1 GDSC1; CTRP2 3.3114 5.8315 3.1172 18.8817
SW684 GDSC1 3.4711 4.6795 2.7876 4.0847
VA-ES-BJ GDSC1 3.689 12.8266 -1.1046 27.4184
HT-1080 GDSC1; CTRP2 3.7268 4.2637 3.7267 15.4406
Rh18 GDSC1; CTRP2 3.8309 4.8442 3.8234 14.7717
KYM-1 GDSC1; CTRP2 3.8624 6.6882 3.4607 15.9788
Tm87-16 CTRP2 4.1142 10.026 2.2817 19.845
G-402 GDSC1; CTRP2 4.565 8.8231 3.2886 14.7836
TE 441.T CTRP2 4.9109 7.4434 4.2672 9.9912
TE 617.T CTRP2 4.9665 10.7 2.7669 15.9255
TTC-709 CTRP2 5.4717 15.9087 0.6272 22.4208
MFH-ino GDSC1 6.6986 17.1058 -0.9721 18.5925
BT-12 CTRP2 7.1538 8.0567 5.746 0.1781
SW982 GDSC1; CTRP2 7.4252 8.9334 5.5241 0.5742
MES-SA GDSC1; CTRP2 7.5369 14.0944 3.1853 9.3465
RKN GDSC1; CTRP2 7.8509 9.0673 5.6502 0.1385
SK-UT-1 GDSC1; CTRP2 8.1694 12.3077 4.4565 3.5163
Rh41 GDSC1; CTRP2 8.1784 9.5542 5.6001 0.1359
Hs 729.T CTRP2 8.2304 12.5092 4.401 3.6535
RD GDSC1; CTRP2 10.0344 18.104 2.9261 6.9757
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.9586 12.1826 1.1013 24.4107
A2780 GDSC1; CTRP2 2.4417 4.9548 2.3476 24.3214
MCAS CTRP2 2.5397 4.573 2.4987 23.4869
OC 314 GDSC1; CTRP2 3.2136 4.8736 3.1788 18.9765
TYK-nu GDSC1; CTRP2 4.0255 7.8197 3.1911 16.556
TOV-21G GDSC1; CTRP2 4.5098 6.022 4.3757 10.6918
COV434 CTRP2 4.5889 11.2602 2.1425 19.2133
Caov-4 GDSC1 4.6556 7.12 2.4152 3.8244
IGROV-1 GDSC1; CTRP2 4.8554 10.7096 2.6594 16.6037
TOV-112D GDSC1; CTRP2 4.9658 10.7315 2.7508 15.9908
Caov-3 GDSC1; CTRP2 4.9723 8.3416 3.9139 11.2635
JHOS-4 GDSC1 5.0648 7.5348 2.4603 2.7771
ES-2 GDSC1 5.3997 6.7578 2.9165 0.2782
OVKATE GDSC1 5.6114 7.1244 2.8659 0.3195
OVCAR-3 GDSC1 5.8248 7.2003 2.9162 0.1502
SNU-119 CTRP2 6.1869 9.996 4.1861 7.5387
OVK18 GDSC1; CTRP2 6.4649 11.9156 3.4514 10.0815
ES2 CTRP2 6.5149 7.6764 4.6619 0.2267
OV-90 GDSC1; CTRP2 6.9299 17.2021 1.1852 17.7563
DOV13 GDSC1; CTRP2 7.1367 11.0047 3.5746 3.3404
OVISE GDSC1; CTRP2 7.2579 8.3818 4.6865 0.0479
SNU-8 CTRP2 7.3601 8.4425 5.6862 0.2196
JHOC-5 CTRP2 7.3702 8.8508 4.5667 0.1501
EFO-21 GDSC1; CTRP2 7.4069 11.1881 4.5002 4.2831
OAW42 GDSC1; CTRP2 7.4455 18.0096 1.1856 16.836
SNU-840 CTRP2 7.4608 9.2804 5.3987 0.9169
HEY A8 CTRP2 7.4767 12.3406 3.9953 6.2011
OAW28 GDSC1; CTRP2 7.698 13.2909 3.6895 7.1012
OV7 CTRP2 7.7519 9.209 5.5599 0.3243
COV644 CTRP2 7.97 10.274 5.2372 1.0332
JHOS-2 GDSC1; CTRP2 7.9808 9.8383 5.4167 0.5429
SK-OV-3 GDSC1; CTRP2 8.0102 9.5036 5.5547 0.2444
FU-OV-1 GDSC1; CTRP2 8.0657 9.6555 5.521 0.2864
COV362 CTRP2 8.1491 10.1259 5.3784 0.5516
JHOM-1 CTRP2 8.1623 9.3207 5.6743 0.0627
OVSAHO CTRP2 8.5285 10.1187 5.5312 0.1533
ONCO-DG-1 CTRP2 8.6186 10.2825 5.507 0.1657
Kuramochi GDSC1; CTRP2 8.6688 10.9489 5.2846 0.5303
OV56 GDSC1; CTRP2 8.735 22.4026 -0.0151 18.3836
RMG-I GDSC1; CTRP2 8.774 14.3707 3.8763 4.9814
OVCAR-5 GDSC1; CTRP2 8.8968 16.8283 2.8041 8.8282
OVCAR-4 GDSC1; CTRP2 9.2177 10.9716 5.4836 0.0989
OVCAR-8 GDSC1; CTRP2 9.3414 17.8433 2.6144 8.9313
EFO-27 GDSC1; CTRP2 13.1251 26.8438 0.7853 10.4107
OVTOKO GDSC1; CTRP2 14.0413 27.0061 1.2389 8.2302
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 6.0554 13.9283 2.1116 16.1518
P-STS CTRP2 8.1349 9.6895 5.5358 0.2393
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 8.1419 9.3666 5.6516 0.0852
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC1; CTRP2 5.6466 10.7067 3.374 11.99
NCI-H2452 GDSC1; CTRP2 5.7304 9.0724 4.2614 8.1229
MPP 89 GDSC1; CTRP2 7.3792 10.8276 4.6527 3.7189
ACC-MESO-1 CTRP2 7.8793 9.1305 5.6384 0.1483
NCI-H2052 GDSC1; CTRP2 8.3202 10.115 5.4534 0.3256
JL-1 CTRP2 8.7549 9.9322 5.6713 0.0226
MSTO-211H GDSC1; CTRP2 8.7727 10.4111 5.518 0.1264
IST-Mes1 GDSC1; CTRP2 10.1032 21.3966 1.4303 11.9894
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 5.0834 7.524 2.4747 2.6579
LNCaP clone FGC GDSC1; CTRP2 5.3887 10.1781 3.4085 12.3938
NCI-H660 CTRP2 5.9674 40.3466 -11.1709 38.5563
PaCa-3 CTRP2 7.8944 13.1272 3.9007 5.9897
DU145 GDSC1; CTRP2 7.9456 14.0033 3.5163 7.4292
VCaP GDSC1; CTRP2 7.9699 12.0894 4.436 3.8215
22Rv1 GDSC1; CTRP2 8.1142 16.0009 1.8645 8.8582
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; CTRP2 3.9124 5.0479 3.8959 14.2592
YD-15 CTRP2 7.5583 12.4229 4.0116 6.0181
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 3.7743 7.4466 1.6481 11.8956
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-5 GDSC1; CTRP2 0.4511 3.6549 0.3895 37.4554
HSC-39 GDSC1 1.7948 5.8026 0.673 26.9308
GSS CTRP2 2.2987 4.1446 2.2795 25.0189
HGC-27 GDSC1; CTRP2 2.3843 4.0554 2.3721 24.4248
GCIY GDSC1 2.7628 3.5801 2.6361 8.2763
TGBC11TKB GDSC1 2.7797 4.2417 2.3737 10.1244
Hs 746.T GDSC1; CTRP2 3.058 16.4336 -1.8093 33.998
MKN45 GDSC1; CTRP2 3.114 13.1643 -0.1782 30.3226
SCH GDSC1 3.123 3.7053 2.9628 4.0645
ECC10 GDSC1 3.4063 4.8591 2.646 5.4212
SNU-16 GDSC1; CTRP2 3.7875 4.8562 3.7782 15.067
SNU-1 GDSC1; CTRP2 3.7961 6.8417 3.3346 16.6422
OCUM-1 GDSC1; CTRP2 4.4279 7.8374 3.5993 13.8919
IM95 GDSC1; CTRP2 4.8347 12.8352 1.5948 20.6352
KATO III GDSC1; CTRP2 5.0811 12.2355 2.1135 18.1933
MKN74 CTRP2 5.2286 8.3916 4.1369 9.7444
RERF-GC-1B GDSC1 5.287 7.4028 2.6259 1.5201
SNU-216 CTRP2 5.4164 9.5569 3.7407 10.9614
NUGC-4 GDSC1; CTRP2 5.4874 8.0678 3.8841 4.3777
MKN28 GDSC1 6.0956 8.3228 2.6201 0.8219
RF-48 GDSC1 6.1458 7.826 2.8162 0.2457
MKN1 GDSC1; CTRP2 6.8099 10.5657 4.3857 5.6254
KE-39 CTRP2 6.8202 12.3857 3.4948 9.2768
MKN7 GDSC1; CTRP2 6.8934 9.9845 4.7292 4.0884
GSU CTRP2 7.0467 7.6785 5.8407 0.0578
NCC-StC-K140 CTRP2 7.3813 10.3742 4.8663 2.8884
ECC12 CTRP2 7.6859 8.7809 5.6898 0.1209
23132/87 GDSC1; CTRP2 7.8261 9.1106 5.6255 0.1806
SNU-668 CTRP2 7.8808 13.0294 3.9382 5.8608
HuG1-N CTRP2 8.0718 10.0568 5.3715 0.6065
Fu97 GDSC1; CTRP2 8.1245 9.4984 5.5999 0.147
NCI-N87 GDSC1; CTRP2 8.4596 10.3495 5.4226 0.3357
NUGC-3 GDSC1; CTRP2 8.473 10.0033 5.5511 0.1398
SNU-719 CTRP2 8.8979 10.5819 5.504 0.1219
SNU-601 CTRP2 9.1077 25.0161 -1.0253 20.4825
AGS GDSC1; CTRP2 9.1223 17.5247 1.7864 7.8353
SH-10-TC CTRP2 9.3022 17.4745 2.7627 8.4458
SNG-M GDSC1; CTRP2 3.9271 6.0324 3.737 14.7702
SNU-685 CTRP2 7.9543 9.0942 5.6783 0.086
SNU-1077 CTRP2 8.3455 10.4019 5.3565 0.5119
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8505C GDSC1; CTRP2 3.1009 4.8274 3.0647 19.7319
TT GDSC1; CTRP2 3.9294 5.0899 3.8148 8.3897
KMH-2 GDSC1 4.5213 6.576 2.5823 2.9545
IHH-4 GDSC1 5.4049 7.2807 2.7265 0.9268
ASH-3 GDSC1 5.4214 6.8066 2.9074 0.2921
K5 GDSC1 5.6696 7.4151 2.7842 0.5256
TT2609-C02 GDSC1; CTRP2 5.7505 9.4641 4.0838 8.8246
WRO GDSC1 5.7886 7.4248 2.8259 0.3483
HTC-C3 GDSC1 5.9372 8.0759 2.6477 0.8289
FTC-133 GDSC1; CTRP2 6.3193 8.2335 5.1696 3.1793
SW579 CTRP2 6.3267 10.979 3.8082 8.8584
CAL-62 GDSC1; CTRP2 6.9601 8.8199 5.3251 1.6462
FTC-238 CTRP2 7.5531 9.1898 5.4805 0.615
8305C GDSC1; CTRP2 7.825 10.6858 4.9858 1.9683
ML-1 [Human leukemia] GDSC1; CTRP2 8.0211 9.5801 5.531 0.2829
B-CPAP GDSC1; CTRP2 8.0247 9.672 5.4985 0.3438
CGTH-W-1 GDSC1; CTRP2 8.0987 9.3973 5.6257 0.1199
BHT-101 GDSC1; CTRP2 8.5006 10.1304 5.5168 0.177
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SAT [Human HNSCC] GDSC1 2.4818 4.9196 1.7641 16.1053
SCC-15 GDSC1 2.8601 3.6169 2.7266 7.1153
OSC-20 GDSC1 2.9312 3.5479 2.8288 6.0095
PCI-15A GDSC1 2.9673 3.8271 2.7504 6.4018
YD-10B CTRP2 3.243 8.7105 1.9987 23.1988
HSC-2 GDSC1; CTRP2 3.7314 5.0361 3.7077 15.4892
FaDu GDSC1; CTRP2 3.7826 4.6251 3.7805 15.0756
NCI-H3118 GDSC1 3.8359 7.7966 1.5219 12.6159
HSC-4 GDSC1; CTRP2 4.5642 6.347 4.3372 10.6702
PCI-06A GDSC1 4.61 10.4956 0.7698 15.2396
BICR 22 GDSC1; CTRP2 4.9795 6.8504 4.594 8.5226
PE/CA-PJ15 GDSC1; CTRP2 5.441 8.3876 4.3385 8.4269
SAS GDSC1 5.5202 7.7373 2.5993 1.3964
KON GDSC1 5.5457 7.5707 2.6754 1.0238
PCI-38 GDSC1 5.6095 7.2985 2.8031 0.4991
OSC-19 GDSC1 5.6838 7.6278 2.7116 0.769
SCC-4 GDSC1; CTRP2 5.8013 6.9099 5.3954 3.2365
Detroit 562 GDSC1; CTRP2 5.8282 12.1044 2.1445 11.4113
PCI-04B GDSC1 5.9085 13.0586 0.4316 13.7352
PCI-30 GDSC1 5.9274 7.799 2.7452 0.5079
BB30-HNC GDSC1 5.9438 7.5163 2.8505 0.2374
HO-1-N-1 GDSC1 5.9571 7.888 2.7245 0.555
LB771-HNC GDSC1 5.9588 8.1339 2.6349 0.8617
YD-8 CTRP2 6.0152 9.2611 4.4117 6.9191
BB49-HNC GDSC1 6.0476 7.98 2.7262 0.5035
BICR 78 GDSC1 6.0512 8.1271 2.6744 0.6623
HO-1-u-1 GDSC1 6.064 7.7164 2.8247 0.2533
Ca9-22 GDSC1 6.0999 7.9762 2.7472 0.421
SKN-3 GDSC1 6.1234 8.0535 2.7287 0.4605
HSC-3 GDSC1; CTRP2 6.1996 7.5763 4.5624 0.6569
DOK GDSC1 6.2012 8.8685 2.4578 1.3887
JHU-022 GDSC1 6.3155 8.1441 2.7675 0.2929
BICR 10 GDSC1 6.3189 7.9566 2.8325 0.1733
KOSC-2 GDSC1 6.3889 8.9439 2.5081 1.0321
CAL-33 GDSC1; CTRP2 6.4916 10.2532 4.3001 6.5115
BICR 18 CTRP2 6.6054 10.1174 4.4544 5.675
JHU-011 GDSC1 6.6198 17.2587 -1.0992 19.2889
SCC-9 GDSC1; CTRP2 6.7835 8.7191 5.2614 2.1079
PE/CA-PJ49 CTRP2 7.1079 11.5446 4.1223 6.2385
SCC-25 GDSC1; CTRP2 7.2963 10.1508 4.9171 2.7969
BICR 6 CTRP2 7.647 10.6331 4.908 2.4277
SNU-1214 CTRP2 7.7226 12.8883 3.8998 6.2305
PE/CA-PJ34 (clone C12) CTRP2 7.8947 12.4549 4.2188 4.7469
CAL-27 GDSC1; CTRP2 7.9014 9.4683 5.5242 0.3391
BICR 16 CTRP2 7.9339 10.5928 5.0849 1.5357
PE/CA-PJ41 (clone D2) CTRP2 7.9801 9.5848 5.5128 0.3321
BHY GDSC1; CTRP2 7.9892 9.6732 5.4834 0.3886
SNU-899 CTRP2 8.1076 11.1045 4.9564 1.8094
BICR 56 CTRP2 8.1559 9.4936 5.613 0.1245
SNU-1066 CTRP2 8.2016 9.6562 5.5729 0.1664
SNU-46 CTRP2 8.2313 16.5145 2.5009 10.9052
SNU-1041 CTRP2 8.2791 9.9236 5.5069 0.2457
BICR 31 GDSC1; CTRP2 8.3546 9.7509 5.5956 0.1102
SNU-1076 CTRP2 14.0729 31.6526 -0.848 13.7358
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-3 GDSC1; CTRP2 3.5972 6.575 3.212 17.6769
SW1710 GDSC1; CTRP2 3.6643 5.5968 3.5541 16.2352
TCCSUP GDSC1; CTRP2 4.7645 7.2843 4.1866 10.6916
T24 GDSC1; CTRP2 5.0432 8.9562 3.6883 12.0173
SW780 GDSC1 5.113 9.0997 1.7831 7.196
5637 GDSC1; CTRP2 5.1589 7.8952 3.7132 5.7621
VM-CUB-1 CTRP2 5.3141 10.2677 3.2971 13.0128
KMBC-2 CTRP2 5.7307 8.6013 4.496 7.1401
UM-UC-1 CTRP2 5.8392 11.9281 2.9299 13.4048
U-BLC1 CTRP2 6.0639 11.1589 3.5034 10.6197
253J CTRP2 6.1882 11.4741 3.4484 10.6081
BC-3C CTRP2 6.2008 7.285 5.5492 1.7985
647V GDSC1; CTRP2 6.8757 13.699 2.8859 11.6303
253J-BV CTRP2 6.9011 11.4606 4.0129 7.0146
HT-1197 GDSC1; CTRP2 7.1856 10.0053 4.9151 4.1324
KU-19-19 GDSC1; CTRP2 7.2475 8.9759 5.4182 1.0277
639V GDSC1; CTRP2 7.3598 9.2543 5.3577 1.1304
RT-112 GDSC1; CTRP2 7.5685 15.2539 2.6398 11.4187
CAL-29 GDSC1; CTRP2 7.5767 9.9888 5.1553 1.6182
SCaBER CTRP2 8.1775 9.6568 5.5637 0.1849
BFTC-905 GDSC1; CTRP2 8.2474 9.5778 5.6168 0.1047
HT-1376 GDSC1; CTRP2 8.5247 15.4162 3.2294 7.7351
JMSU-1 CTRP2 8.5606 9.7983 5.6507 0.0428
RT-4 GDSC1; CTRP2 9.0717 16.352 3.1421 7.349
J82 GDSC1; CTRP2 9.9977 19.3248 2.3386 9.0722
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Ca Ski GDSC1 1.6919 2.8286 1.652 21.0572
TC-YIK GDSC1 1.8247 3.2991 1.7001 19.9573
NEC8 GDSC1 2.7347 3.7068 2.558 8.9823
SKN GDSC1 2.8446 3.6293 2.7051 7.3507
HT-3 GDSC1 2.877 4.1073 2.5326 8.4676
NCC-IT GDSC1 3.0214 4.0305 2.7112 6.4439
PA-1 GDSC1 3.0371 5.5521 1.9821 12.0324
C-33 A GDSC1 3.1372 4.8817 2.404 8.3409
ME-180 GDSC1 3.5823 7.4411 1.4989 13.6466
OMC-1 [Human cervical carcinoma] GDSC1 3.9546 7.15 1.9319 9.1929
JAR GDSC1 4.4179 10.1355 0.8055 15.5977
SiSo GDSC1 4.8041 6.9123 2.5905 2.3951
PEO1 GDSC1 4.8264 10.9146 0.7212 14.9058
HEC-1 GDSC1 5.0666 6.5694 2.8546 0.6738
PWR-1E GDSC1 5.0682 9.9278 1.3643 10.1429
OV17R GDSC1 5.1941 7.4005 2.5827 1.8661
SW954 GDSC1 5.2366 8.4101 2.1709 4.3242
CAL-39 GDSC1 5.4141 9.5606 1.7549 6.7205
OVCA433 GDSC1 5.4574 7.6415 2.6088 1.4163
SW756 GDSC1 5.4759 6.9483 2.8776 0.347
NT2-D1 GDSC1 5.5763 14.7608 -0.6185 19.817
MS751 GDSC1 5.5832 7.2612 2.8064 0.5032
UWB1.289 GDSC1 5.5926 12.4261 0.5224 14.0095
DoTc2 4510 GDSC1 5.7392 7.5153 2.7749 0.5164
JHOS-3 GDSC1 5.761 7.7721 2.6892 0.7982
JEG-3 GDSC1 5.7704 17.3333 -1.7368 23.7067
BPH-1 GDSC1 5.7889 9.298 2.0839 3.908
KGN GDSC1 5.8098 7.5564 2.7872 0.4435
SKG-IIIa GDSC1 5.8221 7.3249 2.8728 0.2292
C-4-I GDSC1 5.9749 15.6754 -0.781 19.5087
OVCA420 GDSC1 5.9988 7.6025 2.8405 0.241
DSH1 GDSC1 6.0426 7.8102 2.7844 0.3503
SW962 GDSC1 6.2038 8.2347 2.6945 0.5187
LB831-BLC GDSC1 6.2682 8.0331 2.7888 0.2639
OVMIU GDSC1 6.9945 9.175 2.6557 0.3131
ACC-OV7 GDSC1 7.1904 9.8084 2.5066 0.584
HEY GDSC1 7.3094 18.3086 -1.1378 17.9243
HeLa GDSC1; CTRP2 7.3716 8.717 5.5859 0.442
SiHa GDSC1 7.7976 16.8098 -0.1285 12.5415
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Receptor tyrosine kinases as therapeutic targets: the model of the MET oncogene. Curr Drug Targets. 2001 Mar;2(1):41-55.
2 Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasion. Mol Cancer Ther. 2003 Nov;2(11):1085-92.