Details of the Drug

General Information of Drug (ID: DMATQB7)

Drug Name
Alpha-Helical lipopeptides FFS
Synonyms FFS
Indication
Disease Entry ICD 11 Status REF
Middle East Respiratory Syndrome (MERS) 1D64 Preclinical [1]
Therapeutic Class
Antiviral Agents
Drug Type
Protein/peptide drug
Sequence
FEEFSKKFEEFSKKFEEFSKKFEEFSKKFEEFSKK-A-K(C16)
Cross-matching ID
TTD ID
D0V0SE

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
MERS-CoV spike glycoprotein (S) TT85VHW A0A140AYZ5_9BETC Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 De Novo Design of -Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery. J Med Chem. 2018 Oct 11;61(19):8734-8745.