General Information of Drug (ID: DMAZJFX)

Drug Name
Ciclosporin
Synonyms
Ciclosporin; Ciclosporin (Ciclosporin A); Ciclosporina; Ciclosporina [INN-Spanish]; Ciclosporine; Ciclosporine [INN-French]; Ciclosporinum; Ciclosporinum [INN-Latin]; Cipol N; Consupren; Cyclosporin; Cyclosporine A; Equoral; Antibiotic S 7481F1; Gengraf; Neoplanta; Neoral; Ramihyphin A; Restasis; S-Neoral; Sandimmun; Sandimmun Neoral; Sandimmune; Sang 35; Sang-35; SangCyA; Sigmasporin Microoral; cyclosporin A; cyclosporine; 59865-13-3; 83HN0GTJ6D; CHEBI:4031; CSA; DSSTox_CID_365; DSSTox_RID_75541; MFCD00274558; MLS001333756; UNII-83HN0GTJ6D
Indication
Disease Entry ICD 11 Status REF
Graft-versus-host disease 4B24 Approved [1]
Psoriasis vulgaris EA90 Approved [2]
Brain injury NA07.Z Phase 4 [3]
Middle East Respiratory Syndrome (MERS) 1D64 Investigative [4]
Severe acute respiratory syndrome (SARS) 1D65 Investigative [4]
Xerophthalmia 5B55.Y Investigative [2]
⏷ Show the Full List of Indication(s)
Affected Organisms
Humans and other mammals
ATC Code
L04AD01: Ciclosporin
L04AD: Calcineurin inhibitors
L04A: IMMUNOSUPPRESSANTS
L04: IMMUNOSUPPRESSANTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L04AD01: Ciclosporin
L04AD: Calcineurin inhibitors
L04A: IMMUNOSUPPRESSANTS
L04: IMMUNOSUPPRESSANTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
S01XA18: Ciclosporin
S01XA: Other ophthalmologicals
S01X: OTHER OPHTHALMOLOGICALS
S01: OPHTHALMOLOGICALS
S: SENSORY ORGANS
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 4 Molecular Weight (mw) 1202.6
Logarithm of the Partition Coefficient (xlogp) 7.5
Rotatable Bond Count (rotbonds) 15
Hydrogen Bond Donor Count (hbonddonor) 5
Hydrogen Bond Acceptor Count (hbondacc) 12
ADMET Property
Absorption Tmax
The time to maximum plasma concentration (Tmax) is 1-8 h [5]
Bioavailability
The bioavailability of drug is 30% [5]
Clearance
The clearance of drug is 22.5 L/h [6]
Elimination
Cyclosporine excretion is primarily biliary with only 3-6% of the dose (including the parent drug and metabolites) excreted in the urine while 90% of the administered dose is eliminated in the bile [5]
Half-life
The concentration or amount of drug in body reduced by one-half in 19 hours [6]
Metabolism
The drug is metabolized via the liver [5]
Vd
The volume of distribution (Vd) of drug is 4-8 L/kg [7]
Adverse Drug Reaction (ADR)
ADR Term Variation Related DOT DOT ID REF
Bone density decreased Not Available PTH OTD721UF [8]
Bone density decreased Not Available BGLAP OTK1YLWQ [8]
Haemolysis Not Available VWF OTNMMA2P [8]
Nephropathy toxic Not Available PPP3R1 OTGQNFJQ [8]
Periodontal disease rs231775 CTLA4 OTYQR611 [9]
Thrombosis Not Available THBD OT8VHLKY [8]
Thrombosis Not Available GNAQ OTOODWTU [8]
Type IV hypersensitivity reaction HLA-B*39:01 HLA-B OTNXFWY2 [10]
⏷ Show the Full List of 8 ADR Information of This Drug
Chemical Identifiers
Formula
C62H111N11O12
IUPAC Name
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Canonical SMILES
CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
InChI
PMATZTZNYRCHOR-CGLBZJNRSA-N
InChIKey
1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1
Cross-matching ID
PubChem CID
5284373
ChEBI ID
CHEBI:4031
CAS Number
59865-13-3
UNII
83HN0GTJ6D
DrugBank ID
DB00091
INTEDE ID
DR0321
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calcineurin (PPP3CA) TTA4LDE PP2BA_HUMAN Inhibitor [2]
HUMAN cyclophilin D (CYP3) TT95SAZ PPIF_HUMAN Inhibitor [4]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [11]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [12]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [13]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4)
Main DME
DE4LYSA CP3A4_HUMAN Substrate [14]
Cytochrome P450 3A5 (CYP3A5)
Main DME
DEIBDNY CP3A5_HUMAN Substrate [15]
Cytochrome P450 3A7 (CYP3A7) DERD86B CP3A7_HUMAN Substrate [16]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8) OTX1DWEF DHB8_HUMAN Gene/Protein Processing [17]
(E3-independent) E2 ubiquitin-conjugating enzyme OTHGS2VA UBE2O_HUMAN Gene/Protein Processing [18]
(Lyso)-N-acylphosphatidylethanolamine lipase (ABHD4) OTQK3M9X ABHD4_HUMAN Gene/Protein Processing [18]
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1) OTG2T749 CP24A_HUMAN Gene/Protein Processing [19]
1,4-alpha-glucan-branching enzyme (GBE1) OTK2N05B GLGB_HUMAN Gene/Protein Processing [20]
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1) OTX65INE PLCA_HUMAN Gene/Protein Processing [18]
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) OT5I4Y9K PLCB_HUMAN Gene/Protein Processing [18]
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) OTNY3VMD PLCE_HUMAN Gene/Protein Processing [18]
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3) OTAUR5TG PLCC_HUMAN Gene/Protein Processing [18]
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5) OTY829Z3 ABHD5_HUMAN Gene/Protein Processing [18]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Graft-versus-host disease
ICD Disease Classification 4B24
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Calcineurin (PPP3CA) DTT PPP3CA 5.29E-01 1.74E-03 9.99E-03
P-glycoprotein 1 (ABCB1) DTP P-GP 2.00E-01 2.57E-02 6.18E-02
Breast cancer resistance protein (ABCG2) DTP BCRP 6.07E-04 1.66E-01 4.54E-01
Multidrug resistance-associated protein 2 (ABCC2) DTP MRP2 7.41E-21 4.03E-01 1.33E+00
Cytochrome P450 3A5 (CYP3A5) DME CYP3A5 5.05E-02 4.52E-01 5.39E-01
Cytochrome P450 3A4 (CYP3A4) DME CYP3A4 8.67E-01 -3.83E-03 -1.24E-02
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 139 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 6.6174 10.4327 3.5212 3.9259
JK1 CTRP2 6.8892 12.6082 2.6675 6.9145
JM1 CTRP2 5.1387 9.3768 2.9563 8.5915
KMS-34 CTRP2 -2.463 2.0953 -2.5714 50.0144
Karpas-620 CTRP2 -1.8331 3.3216 -2.0708 46.1499
Toledo CTRP2 -1.205 9.3668 -3.3002 44.5577
PF-382 CTRP2 -1.0696 -0.0517 -1.0696 40.7321
KMS-27 CTRP2 -1.0086 -0.1152 -1.0086 40.3259
HDLM-2 CTRP2 -0.9947 2.1151 -1.0339 40.3483
KMS-26 CTRP2 -0.9945 -0.0738 -0.9945 40.2321
KMS-21-BM CTRP2 -0.7447 3.3855 -0.91 39.0382
Mono-Mac-1 CTRP2 0.5406 5.7546 -0.0815 32.025
REC-1 CTRP2 0.7809 7.4616 -0.4358 32.2773
SK-MM-2 CTRP2 0.8168 5.0142 0.2281 25.4806
SEM CTRP2 0.8699 5.1044 0.4721 29.1581
NALM-6 CTRP2 1.1315 5.4514 0.4082 23.7932
BL-70 CTRP2; CTRP1 1.2597 3.8212 1.1734 25.5783
KMS-28BM CTRP2 1.4705 9.4942 -0.5764 30.5322
SUP-M2 CTRP2 1.6096 2.7791 1.6079 22.8889
Mino CTRP2 1.6285 5.1547 1.0521 19.7229
TALL-1 [Human adult T-ALL] CTRP2 1.6304 6.776 0.7354 25.8989
Ri-1 CTRP2 1.6962 16.2926 -3.5663 36.1655
EoL-1 CTRP2 1.724 3.0569 1.7189 22.138
GA-10 CTRP2 1.8344 3.7215 1.7944 21.5201
RCH-ACV CTRP2 1.8887 13.9524 -2.2516 33.3603
DB CTRP2 1.9687 6.6878 1.1302 23.4996
SUP-T11 CTRP2 2.0553 5.2588 1.7213 21.0875
A4/Fukuda CTRP2 2.1534 8.189 0.2644 21.3809
GDM-1 CTRP1 2.1895 4.288 2.0992 41.4723
Daudi CTRP2 2.2267 3.9337 2.1864 18.9077
Pfeiffer CTRP2 2.3656 4.6215 2.2246 18.3323
Mono-Mac-6 CTRP2 2.5358 22.2812 -5.7446 37.1346
HH [Human lymphoma] CTRP2 2.6253 4.9258 2.4358 16.7759
BDCM CTRP2 2.6464 5.5827 2.2628 17.3441
KMS-12-BM CTRP2 2.6704 3.8977 2.6546 15.8689
RPMI-8226 CTRP2; CTRP1 2.6813 4.4513 2.6012 16.0976
MOLP-8 CTRP2 2.7401 6.2228 2.1322 17.566
NCI-H929 CTRP2 2.8223 7.0415 1.8856 18.2848
NOMO-1 CTRP1 2.9506 4.5326 2.8774 30.6435
Ku812 CTRP2; CTRP1 2.9702 4.6244 2.8817 14.205
PL21 CTRP2; CTRP1 3.0057 5.9453 2.5261 15.4031
697 CTRP2 3.1267 8.115 1.7186 18.1354
EB1 CTRP2 3.1568 5.2926 2.9117 13.4431
THP-1 CTRP2; CTRP1 3.1705 4.8773 3.0446 13.0043
KMS-11 CTRP1 3.1976 5.0099 3.0407 27.7405
U-937 CTRP2; CTRP1 3.2911 5.5197 2.9867 12.8543
SKM-1 CTRP2; CTRP1 3.3032 4.0266 3.3 11.6958
AML-193 CTRP2 3.3176 4.4131 3.2872 11.607
MOLM-16 CTRP2; CTRP1 3.3337 4.9185 3.2125 11.9027
OPM-2 CTRP2 3.3531 4.5804 3.3014 11.4438
SU-DHL-5 CTRP1 3.3878 3.9733 3.3868 23.8802
MC116 CTRP2; CTRP1 3.4031 3.8625 3.403 11.0208
OCI-AML-3 CTRP2; CTRP1 3.4126 4.1374 3.4081 10.9723
HT CTRP2; CTRP1 3.4138 4.6971 3.3478 11.1749
KE-97 CTRP2; CTRP1 3.42 5.0255 3.2793 11.3985
NU-DUL-1 CTRP2; CTRP1 3.433 4.3485 3.4165 10.8771
WSU-DLCL2 CTRP2; CTRP1 3.4604 3.9374 3.4601 10.6398
DEL CTRP2 3.6087 3.9377 3.6087 9.5649
LP-1 CTRP2; CTRP1 3.7903 11.0756 0.9374 19.574
SET-2 CTRP2 3.8574 4.5469 3.8434 7.955
HD-MY-Z CTRP2 3.9086 6.9661 3.0271 10.9603
MOLT-16 CTRP2 4.0197 12.1972 0.5819 20.2617
CA46 CTRP2 4.1501 7.5831 2.9699 10.6133
ST486 CTRP2 4.2417 8.5027 2.6079 11.8955
JVM-3 CTRP2 4.3254 9.6895 2.0985 13.7975
AMO1 CTRP2; CTRP1 4.4628 5.9068 4.0738 5.4507
Peer CTRP2 4.615 12.4577 0.9741 17.5596
RL CTRP2 4.6222 7.0742 3.0129 3.8274
Ci-1 CTRP2 4.6278 6.0979 3.489 1.7556
LAMA-84 CTRP2 4.6281 6.9393 2.2125 1.6313
HuT 78 CTRP2 4.6438 5.6275 4.3764 3.6907
RS4;11 CTRP2 4.6945 14.1321 -0.4384 18.1117
KM-H2 CTRP2 4.7789 7.7864 1.923 2.6232
P3HR-1 CTRP2; CTRP1 4.822 6.564 4.1008 4.5048
HuNS1 CTRP2 4.8655 9.9432 1.78 8.8351
HEL CTRP2 5.2058 6.4839 2.6428 0.109
P12-Ichikawa CTRP2 5.2357 7.7016 3.8717 4.5723
KE-37 CTRP2 5.2622 6.2363 4.6188 1.4101
L-1236 CTRP2 5.2886 16.7537 -0.608 21.472
SIG-M5 CTRP2 5.3686 6.2781 3.7913 0.1304
KMS-18 CTRP2 5.3847 15.0444 0.3251 18.3112
JeKo-1 CTRP2 5.3939 8.5549 2.8261 3.468
KMM-1 CTRP2 5.4421 7.7289 4.0175 3.6071
OCI-M1 CTRP2 5.6055 7.2925 3.5039 0.7086
HL-60 CTRP2 5.6156 6.9878 3.6281 0.369
OCI-Ly10 CTRP2; CTRP1 5.656 7.7802 4.158 2.7748
JURL-MK1 CTRP2 5.7439 8.7347 3.7447 4.2518
RPMI-6666 CTRP2 5.8549 21.5624 -2.5493 25.4456
HEL 92.1.7 CTRP2 5.8735 6.9514 3.741 0.0904
U266B1 CTRP2 5.9295 10.2909 3.1173 6.5394
EM-2 CTRP2 5.936 13.4988 1.5354 12.8913
TF-1 CTRP2 5.9722 9.2602 3.6507 4.2912
K-562 CTRP2 6.0167 7.7561 3.5048 0.4722
Jurkat CTRP2 6.0906 13.9674 -0.1277 9.5106
SU-DHL-4 CTRP2; CTRP1 6.0932 8.4969 4.1064 2.3899
MOLM-13 CTRP2 6.2551 9.8415 3.5644 4.2351
MOLT-3 CTRP2 6.3015 7.3428 4.6995 0.2149
A3/Kawakami CTRP2 6.3305 7.2813 4.7335 0.144
KCL-22 CTRP2 6.367 9.3671 3.0182 1.6765
Karpas-422 CTRP2 6.4135 11.8545 2.7019 7.4749
SU-DHL-8 CTRP2 6.458 8.7095 4.2127 1.5325
SU-DHL-1 CTRP2 6.4948 8.2933 4.4102 0.8563
Namalwa CTRP2 6.5739 9.3501 3.9931 2.1957
MOTN-1 CTRP2 6.5794 8.0269 4.5565 0.4075
HPB-ALL CTRP2 6.6196 14.5359 1.5388 11.7202
OCI-AML-5 CTRP2 6.6534 7.9737 4.6076 0.2661
P31/FUJ CTRP2 6.6921 8.095 4.5781 0.3105
Kasumi-1 CTRP2 6.7064 14.6256 1.5585 11.5057
EHEB CTRP2 6.7359 8.603 3.4799 0.2621
EJM CTRP2; CTRP1 6.767 9.3627 4.1085 1.663
SU-DHL-10 CTRP2 6.7999 7.9511 4.6721 0.1203
RPMI-8402 CTRP2 6.8411 8.807 4.3661 0.7508
L-363 CTRP2 6.86 8.0382 4.6637 0.1189
Hs 611.T CTRP2 6.8709 8.8936 4.3451 0.7901
OCI-Ly19 CTRP2 6.8872 9.1733 4.2382 1.0891
L-540 CTRP2 6.9239 10.8138 3.5348 3.5029
KYO-1 CTRP2 6.9912 8.2406 4.6411 0.1215
M-07e CTRP2 7.0019 11.6277 3.206 4.661
NU-DHL-1 CTRP2 7.0119 15.916 1.1484 12.5412
KO52 CTRP2 7.0864 12.2355 2.9749 5.4461
MM1.S CTRP2 7.1024 8.744 4.5031 0.3071
CML-T1 CTRP2 7.1597 12.6026 2.8493 5.837
JJN-3 CTRP2 7.1652 12.959 2.6843 6.4693
OCI-Ly3 CTRP2 7.1707 9.3484 4.3011 0.7307
Ki-JK CTRP2 7.1787 9.011 4.4347 0.4139
L-428 CTRP2 7.2411 14.4464 2.0242 8.9144
Granta-519 CTRP2 7.2461 8.9497 4.4846 0.2934
KHM-1B CTRP2 7.2766 21.3023 -1.3075 19.9257
NCO2 CTRP2 7.2884 16.522 1.0512 12.46
SR CTRP2 7.3225 8.7854 4.5721 0.1426
MOLP-2 CTRP2 7.6423 16.8168 1.1575 11.5458
MHH-CALL-4 CTRP2 7.7634 9.7932 4.38 0.316
SUP-HD1 CTRP2 7.9125 9.8687 4.4097 0.232
Kasumi-2 CTRP2 7.9257 25.8162 -3.0489 23.1323
SUP-B15 CTRP2 8.097 17.5431 1.1196 11.0269
MOLM-6 CTRP2 8.6013 20.3342 0.1223 13.6657
F-36P CTRP2 9.6694 19.8334 1.0568 9.2166
CMK CTRP2 12.195 22.7722 1.1914 6.2257
KMS-20 CTRP2 12.4658 40.6133 -6.9989 24.3057
⏷ Show the Full List of 139 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 5.8949 9.3608 3.5474 4.8281
TE8 CTRP2 6.5612 8.4471 3.4688 0.3329
TE-6 CTRP2 1.9842 7.9249 0.2223 22.0084
KYSE-140 CTRP2; CTRP1 3.567 6.4989 2.8957 12.4414
KYSE-410 CTRP2; CTRP1 3.6126 7.8749 2.3181 14.6277
TE-5 CTRP2 3.7317 5.6352 3.4161 9.892
TE-4 CTRP2 3.8109 12.3468 -0.2748 19.3767
KYSE-450 CTRP2; CTRP1 4.9639 8.6585 3.1793 8.0762
TE-11 CTRP2 4.9815 11.6306 1.0326 11.8253
KYSE-520 CTRP2 5.3496 10.9584 2.3378 10.7592
TE-14 CTRP2 5.6488 9.8723 3.1138 7.017
TE-10 CTRP2 5.7956 10.2376 3.0441 7.059
TE-9 CTRP2 6.5156 10.5883 3.3818 4.605
KYSE-180 CTRP2 6.6153 8.4006 3.5063 0.252
EC-GI-10 CTRP2 6.7444 10.9501 3.3596 4.3921
OE19 CTRP2 6.7615 8.5096 4.4482 0.5795
KYSE-70 CTRP2 7.244 9.8584 4.1295 1.159
KYSE-150 CTRP2 7.3088 8.5606 4.6442 0.0707
KYSE-510 CTRP2 7.3445 12.6053 2.9656 5.1566
COLO 680N CTRP2 7.5458 8.8606 4.6251 0.0605
OE33 CTRP2 7.5538 9.3358 4.4641 0.2394
OE21 CTRP2 7.5866 9.5264 4.408 0.3214
TE-1 CTRP2 7.8961 9.5003 4.531 0.0969
KYSE-30 CTRP2 9.1644 15.1769 2.8598 3.6363
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 7.7168 9.6041 4.4301 0.2494
KP-3 CTRP2; CTRP1 2.9007 7.9293 1.5825 19.3193
Capan-2 CTRP2; CTRP1 3.7684 10.0545 1.4182 17.8174
CFPAC-1 CTRP2; CTRP1 3.7687 6.0657 3.2891 10.3648
Panc 03.27 CTRP2; CTRP1 3.9696 8.7519 2.2411 14.0912
Panc 10.05 CTRP2; CTRP1 4.0697 8.7937 2.3143 13.565
PaTu 8902 CTRP2; CTRP1 4.208 6.7808 3.4158 8.7373
QGP-1 CTRP2; CTRP1 4.3043 7.43 3.1978 9.4025
HPAC CTRP2; CTRP1 4.5753 6.0404 4.1238 4.9709
HuP-T4 CTRP2; CTRP1 4.7917 9.3459 2.6889 10.4687
SNU-213 CTRP2 4.9206 9.8357 1.8746 8.3233
KP-4 CTRP2 5.1005 7.5995 3.8133 5.0673
SUIT-2 CTRP2; CTRP1 5.2257 6.994 4.2266 3.1861
PaTu 8988s CTRP2 5.3601 13.1497 1.2517 15.0319
MIA PaCa-2 CTRP2 5.4514 7.6798 4.0487 3.4624
Capan-1 CTRP2 5.9061 13.0217 1.7491 12.1149
PSN1 CTRP2 5.9993 9.7997 3.4079 5.2389
SW1990 CTRP2 6.0397 7.9313 4.3218 1.5695
SU.86.86 CTRP2 6.1043 12.4159 1.4605 8.1512
HPAF-II CTRP2 6.5006 13.1136 2.1496 9.5449
SNU-410 CTRP2 6.5406 14.6708 1.4141 12.3202
Hs 766T CTRP2 6.6618 8.3042 4.4845 0.5415
HuP-T3 CTRP2 6.675 8.1611 3.6113 0.1038
PaTu 8988t CTRP2 6.7511 7.7834 4.7126 0.0817
L3.3 CTRP2 6.8552 8.4671 4.5055 0.3975
YAPC CTRP2 6.9005 8.2096 4.6183 0.1723
BxPC-3 CTRP2 6.9407 9.799 3.9995 1.8135
Panc 05.04 CTRP2 6.9632 8.7317 4.4502 0.4729
TCC-Pan2 CTRP2 6.9819 8.4508 4.5628 0.2389
KP-2 CTRP2 7.2949 8.8224 4.549 0.1784
Panc 02.03 CTRP2 7.5207 9.242 4.485 0.2506
AsPC-1 CTRP2 7.5618 16.3684 1.3183 11.0839
PK-45H CTRP2 7.6768 9.4671 4.4637 0.2105
PK-59 CTRP2 7.8091 9.5599 4.4798 0.1628
Panc 04.03 CTRP2 7.8171 13.3715 2.9019 4.8375
DAN-G CTRP2 10.1908 26.2072 -1.6161 16.518
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 8.1733 10.4301 4.3083 0.3676
Malme-3M CTRP2 3.021 18.4005 -3.3868 32.7724
Hs 852.T CTRP2; CTRP1 3.2467 5.5917 2.9138 13.2553
COLO 741 CTRP2; CTRP1 3.2864 6.1764 2.7359 13.8193
G-361 CTRP2; CTRP1 3.3504 4.0893 3.3463 11.3847
Hs 944.T CTRP2; CTRP1 3.7373 4.4552 3.7261 8.8335
WM115 CTRP2 3.7661 5.1889 3.6074 9.0769
Hs 936.T CTRP2; CTRP1 4.0075 6.0468 3.5459 8.723
WM266-4 CTRP2 4.0199 5.4668 3.788 7.6655
A-375 CTRP2; CTRP1 4.388 5.49 4.1764 5.2432
SK-MEL-1 CTRP2; CTRP1 4.4933 6.5418 3.8059 6.4644
HT-144 CTRP2 4.5206 5.7458 4.1985 4.7154
UACC-257 CTRP2 4.5497 7.6416 3.3136 8.2895
SK-MEL-5 CTRP2; CTRP1 4.7584 5.6711 4.4768 3.093
SK-MEL-28 CTRP2; CTRP1 5.0013 5.9544 4.5623 2.1991
RVH-421 CTRP2 5.0067 7.3826 3.8437 5.12
MeWo CTRP2 5.0197 7.5082 3.7918 5.3127
IGR-37 CTRP2 5.138 6.949 4.1689 3.5031
CJM [Human melanoma] CTRP2 5.9728 7.6228 3.537 0.4173
RPMI-7951 CTRP2 6.0563 8.4874 4.0754 2.4838
SK-MEL-2 CTRP2 6.1387 7.3837 4.612 0.5109
Mel Ho CTRP2 6.1452 7.923 3.4954 0.4357
WM88 CTRP2 6.2315 9.4181 3.7501 3.5301
HMCB CTRP2 6.319 7.4988 4.6478 0.3185
Hs 688(A).T CTRP2 6.3306 7.5815 4.6208 0.3767
Hs 895.T CTRP2 6.4691 8.1482 4.4576 0.7336
Hs 294T CTRP2 6.4964 9.2576 3.9895 2.2922
WT2-iPS CTRP2 6.5161 7.5156 4.7202 0.117
A101D CTRP2 6.5342 7.7002 4.6608 0.2072
IPC-298 CTRP2 6.5801 7.861 4.6198 0.2691
K029AX CTRP2 6.6659 8.036 4.5894 0.2975
SK-MEL-30 CTRP2 6.6715 7.8513 4.6594 0.1687
Hs 839.T CTRP2 6.7086 7.647 4.7441 0.0572
IGR-39 CTRP2 6.8225 8.3342 4.542 0.3334
SK-MEL-3 CTRP2 6.8417 10.6674 3.5522 3.5335
Hs 940.T CTRP2 6.8497 9.6838 4.0003 1.8948
A2058 CTRP2 6.8852 7.9107 4.7164 0.0596
WM983B CTRP2 6.906 10.6488 3.5997 3.2807
Mel JuSo CTRP2 6.9194 8.2313 4.6178 0.1685
SK-MEL-24 CTRP2 6.9302 12.5592 2.7186 6.6563
SK-MEL-31 CTRP2 7.0479 8.3811 4.6128 0.1461
IGR-1 CTRP2 7.0481 8.3205 4.6339 0.1194
COLO 800 CTRP2 7.2205 8.884 4.4986 0.277
UACC-62 CTRP2 7.2227 8.4715 4.6443 0.0811
MDA-MB-435S CTRP2 7.2272 8.5973 4.6028 0.1235
WM793 CTRP2 7.3245 8.8503 4.5502 0.1703
WM1799 CTRP2 7.4115 8.7124 4.6286 0.0717
LOX-IMVI CTRP2 7.4698 9.2175 4.4744 0.2454
COLO 792 CTRP2 7.7604 10.6347 4.0581 1.0297
COLO 829 CTRP2 11.3921 26.2936 -0.8709 13.0531
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 4.9462 8.602 3.1831 8.0136
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 CTRP2 4.0158 10.665 1.3368 17.4929
SK-N-DZ CTRP2 4.6827 6.2626 4.1127 4.6752
SK-N-AS CTRP2 5.1917 8.6909 3.3424 6.8739
IMR-32 CTRP2 5.3489 6.5099 3.6975 0.3306
SK-N-FI CTRP2 5.4228 10.5066 1.9112 7.316
Kelly CTRP2 6.7554 12.7975 2.4845 7.83
MHH-NB-11 CTRP2 6.7614 8.4058 4.4888 0.4791
NH-6 CTRP2 6.9164 12.4678 2.7531 6.5398
SK-N-SH CTRP2 7.0563 11.3153 3.3848 3.9134
CHP-126 CTRP2 7.0857 8.9239 4.4288 0.4657
SK-N-BE(2) CTRP2 7.144 10.9785 3.5906 3.052
NB1 CTRP2 7.5246 8.894 4.6066 0.0769
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-28 CTRP2 -1.0878 0.0684 -1.0879 40.8539
SNU-308 CTRP2 4.3141 9.9166 1.9758 14.318
HuCC-T1 CTRP2 4.8835 6.4202 4.2182 3.7962
SNU-478 CTRP2 6.4755 11.0378 3.1402 5.6218
SNU-869 CTRP2 7.19 13.5687 2.4105 7.498
SNU-1196 CTRP2 7.2598 8.5069 4.6453 0.0755
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-673 CTRP2 4.3847 6.0786 3.9105 6.2138
SK-ES-1 CTRP2 4.5284 7.8948 3.1693 8.937
SaOS-2 CTRP2 4.8887 7.8333 3.5181 6.7223
MG-63 CTRP2 5.1788 8.1307 2.887 3.5113
U2OS CTRP1 5.2506 8.0673 3.7113 11.3084
SJSA-1 CTRP2 5.8962 8.5189 3.1357 1.6871
Hs 822.T CTRP2 5.9082 6.9124 4.6944 0.4283
Hs 888.T CTRP2 5.9567 10.4641 3.0521 6.7636
SK-N-MC CTRP2 6.0327 14.6898 1.0185 14.6596
CAL-78 CTRP2 6.0901 8.4312 4.1229 2.2593
SW1353 CTRP2 6.1324 7.9875 3.4656 0.5108
TC71 CTRP2 6.3809 8.3439 4.3303 1.2031
RD-ES CTRP2 6.5697 21.9794 -2.1879 23.3561
G-292 clone A141B1 CTRP2 6.9852 10.8499 3.5553 3.3563
HOS CTRP2 7.1382 8.7053 4.5314 0.2458
MHH-ES-1 CTRP2 7.7951 9.3443 4.5486 0.094
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 66 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 3.2777 4.8841 3.1577 12.1862
MCF-7 CTRP2; CTRP1 3.979 8.3949 2.4233 13.3292
HCC1395 CTRP2 4.7592 10.4203 2.1153 12.8174
CAL-85-1 CTRP2 4.8364 7.9176 3.431 7.1938
MDA-MB-453 CTRP2 5.2344 7.3849 4.0285 3.9173
HMC-1-8 CTRP2 5.4431 6.5664 3.7154 0.248
CAL-120 CTRP2 5.4538 6.686 4.5346 1.4695
HCC1419 CTRP2 5.7708 9.6713 3.3049 6.0221
AU565 CTRP2 5.8695 10.332 3.0527 6.9021
MDA-MB-415 CTRP2 5.8751 8.5191 3.9411 3.2578
ZR-75-30 CTRP2 5.9309 10.1176 3.2033 6.1834
HCC1937 CTRP2 6.3329 13.8674 1.6553 11.7477
KPL-1 CTRP2 6.3433 7.0543 4.8172 0.0386
CAMA-1 CTRP2 6.4277 7.8874 3.6173 0.1375
CAL-51 CTRP2 6.6566 9.935 3.7763 2.9047
ZR-75-1 CTRP2 6.7011 7.9174 4.647 0.1805
BT-20 CTRP2 6.8173 11.5175 3.1393 5.1572
JIMT-1 CTRP2 6.9162 8.0574 4.6774 0.0929
HCC1428 CTRP2 7.0463 8.5944 4.5358 0.2662
Hs 578Bst CTRP2 7.2655 17.6235 0.4962 14.4324
BT-549 CTRP2 7.3689 9.59 4.2943 0.6437
HCC202 CTRP2 7.3826 9.6576 4.274 0.6857
HCC1954 CTRP2 7.385 9.8044 4.2173 0.8271
HCC38 CTRP2 7.3853 12.6364 2.9766 5.0649
MDA-MB-231 CTRP2 7.4164 9.255 4.4402 0.3182
HCC1806 CTRP2 7.5106 8.9598 4.5794 0.1033
HCC1143 CTRP2 8.0528 10.6449 4.1815 0.5908
MDA-MB-361 CTRP2 8.6591 17.153 1.6721 14.8666
Hs 578T CTRP2 8.8979 24.9659 -1.9161 19.0453
HCC1500 CTRP2 8.9576 20.9817 0.0539 13.3872
MDA-MB-468 CTRP2 10.0268 20.0223 1.1877 8.3726
T-47D CTRP2 10.0764 22.1252 0.2448 11.3455
BT 416 CTRP2 2.3025 3.5581 2.2932 18.2981
BT 131 CTRP2 2.616 3.8276 2.6027 16.2227
BT 248 CTRP2 2.758 4.2523 2.7124 15.387
BT 428 CTRP2 2.9211 6.478 2.2235 16.7142
BT 286 CTRP2 4.537 7.6903 3.278 8.4658
BT 271 CTRP2 4.7471 6.2388 4.1844 4.2328
BT147 CTRP2 5.0769 8.9891 3.0991 8.1118
BT 216 CTRP2 5.2117 8.4834 3.4622 6.3342
BT 422 CTRP2 5.5446 10.5474 2.6978 8.9228
BT 482 CTRP2 5.6535 9.5412 3.2813 6.3135
BT 172 CTRP2 5.6791 8.6492 3.7397 4.3736
BT 179 CTRP2 6.2428 7.6587 4.5494 0.6213
BT 320 CTRP2 6.257 7.3764 4.6683 0.3003
BT 444 CTRP2 6.3375 7.4465 4.6755 0.2498
BT 333 CTRP2 6.4336 7.9049 4.5394 0.5279
BT 145 CTRP2 6.5057 8.7522 4.22 1.4626
BT 498 CTRP2 6.5262 7.6756 4.6666 0.1993
BT 232 CTRP2 6.5506 8.7628 4.2396 1.3559
BT 245 CTRP2 6.5571 10.4734 3.4634 4.229
BT 504 CTRP2 6.6557 8.0686 4.5729 0.3361
BT 359 CTRP2 6.694 8.3923 4.4642 0.576
BT164 CTRP2 6.7047 7.7411 4.7105 0.0917
BT 231 CTRP2 6.7129 10.9541 3.3374 4.5191
BT 330 CTRP2 6.7752 8.6222 4.4098 0.6724
BT 340 CTRP2 6.8737 7.9922 4.6846 0.092
BT 328 CTRP2 6.9399 8.1001 4.6711 0.0958
BT 112 CTRP2 6.9968 8.312 4.6181 0.15
BT 159 CTRP2 7.0665 8.5789 4.5493 0.2368
BT 239 CTRP2 7.2281 14.406 2.0347 8.8929
BT 224 CTRP2 7.3822 8.513 4.6849 0.0363
BT 187 CTRP2 7.4132 11.8076 3.3735 3.554
BT 139 CTRP2 8.6525 16.0942 2.1584 6.5892
BT 440 CTRP2 9.4504 19.9589 0.8613 10.1309
BT 228 CTRP2 10.2602 20.6522 1.0398 8.597
⏷ Show the Full List of 66 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 2.6804 6.9629 1.7708 19.1098
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-466 CTRP2 -1.7097 -1.1292 -1.7097 44.9967
42-MG-BA CTRP2 -0.4632 1481.7655 -737.9108 49.926
LN-18 CTRP2 -0.3941 0.7246 -0.3941 36.2321
SF539 CTRP2 3.3855 4.7119 3.3128 11.3013
SF268 CTRP2 3.7383 8.4201 2.1743 14.8237
Hs 683 CTRP2 4.2341 5.7594 3.8981 6.6515
KNS-60 CTRP2 4.5312 6.1954 3.3765 2.3848
D283 Med CTRP2 4.6922 14.1856 0.1771 20.1973
SW1783 CTRP2 4.7761 11.3893 0.9933 12.3759
GaMG CTRP2; CTRP1 5.0446 6.5538 4.2995 3.2163
SNU-489 CTRP2 5.1263 7.0713 4.0983 3.8214
SNU-626 CTRP2 5.133 8.2178 3.5309 6.1926
SF295 CTRP2; CTRP1 5.186 6.665 4.3591 2.7023
SNU-1105 CTRP2 5.3535 8.6162 2.7713 3.7518
SNU-738 CTRP2 5.457 6.8743 4.4463 1.8205
GB-1 CTRP2 5.6042 7.6335 4.1814 2.6788
DK-MG CTRP2 5.8241 13.0188 1.6869 12.5029
U-87MG ATCC CTRP2 5.8457 7.2427 3.6271 0.2762
KALS-1 CTRP2 5.9336 9.653 3.4325 5.2387
YH-13 CTRP2 6.0965 9.9023 3.4266 5.017
CCF-STTG1 CTRP2 6.2516 7.4946 4.6197 0.4217
CAS-1 CTRP2 6.392 8.2365 4.3822 1.0236
LN-229 CTRP2; CTRP1 6.5151 12.2063 2.6141 7.746
SF126 CTRP2 6.5564 8.1945 4.4802 0.6139
NMC-G1 CTRP2 6.5741 7.809 4.6367 0.2384
GMS-10 CTRP2 6.5757 8.1679 4.4996 0.5507
M059K CTRP2 6.6276 10.7986 3.3556 4.5593
SNU-201 CTRP2 6.6617 7.9607 4.6157 0.2475
U-251MG CTRP2 6.7206 13.4928 2.1225 9.3082
Becker CTRP2 6.7241 11.0083 3.3191 4.576
Daoy CTRP2 6.8186 10.1392 3.7797 2.7119
YKG-1 CTRP2 7.0024 8.4307 4.578 0.2079
GOS-3 CTRP2 7.02 8.9673 4.3836 0.6035
TM-31 CTRP2 7.0222 8.1084 4.6972 0.0597
A-172 CTRP2 7.0662 11.1139 3.4832 3.533
ONS-76 CTRP2 7.2884 9.3202 4.3635 0.5214
KNS-42 CTRP2 7.3864 8.8584 4.57 0.1333
DBTRG-05MG CTRP2 7.438 8.9293 4.564 0.131
SW1088 CTRP2 7.5755 9.6102 4.3729 0.3885
8-MG-BA CTRP2 7.6289 9.1921 4.5419 0.1237
T98G CTRP2 7.9579 9.3558 4.6002 0.0433
SNB-75 CTRP2 9.7992 21.2299 0.4879 10.9174
U-118MG CTRP2 11.7992 26.8348 -0.868 12.5836
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-151 CTRP2; CTRP1 2.166 4.5679 2.0211 19.7523
HEC-265 CTRP2; CTRP1 2.3158 4.3113 2.2313 18.5449
MFE-319 CTRP2; CTRP1 2.8309 12.5923 -0.6946 27.2159
HEC-6 CTRP2; CTRP1 3.4038 4.8327 3.309 11.3425
KLE CTRP2; CTRP1 3.4327 5.1765 3.2507 11.4639
JHUEM-1 CTRP2 3.9184 4.5957 3.9028 7.5541
JHUEM-2 CTRP2; CTRP1 4.026 6.0608 3.5591 8.6221
HEC-108 CTRP2; CTRP1 4.1081 6.2063 3.5797 8.3269
HEC-1-A CTRP2 4.1583 6.5208 3.4811 8.5084
HEC-251 CTRP2; CTRP1 4.3741 5.5067 4.155 5.3638
HEC-59 CTRP2; CTRP1 5.3964 6.8371 4.433 2.0447
JHUEM-7 CTRP2 6.2786 16.1299 0.4937 16.0878
HEC-1-B CTRP2 6.3514 8.0213 3.5416 0.2683
JHUEM-3 CTRP2 6.6807 13.1146 2.2783 8.7571
ESS-1 CTRP2 6.7517 8.6921 4.3706 0.7949
MFE-296 CTRP2 7.3478 10.0127 4.1162 1.1271
EFE-184 CTRP2 7.4832 9.009 4.5528 0.136
AN3-CA CTRP2 7.61 10.9283 3.8654 1.6899
HEC-50B CTRP2 7.854 9.7309 4.4365 0.2083
EN CTRP2 9.2916 20.3633 0.5694 11.2913
RL95-2 CTRP2 10.4476 21.7995 0.627 9.7095
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 4.834 8.2457 3.2744 7.9381
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VMRC-RCW CTRP2; CTRP1 3.6393 5.5372 3.3569 10.4645
UO-31 CTRP2 4.0152 8.1108 2.5871 12.4964
CAL-54 CTRP2 4.6497 10.2062 2.1276 12.992
KMRC-3 CTRP2 4.7033 11.9283 1.3142 16.0988
TUHR4TKB CTRP2 5.0313 7.6499 3.7307 5.5472
TUHR14TKB CTRP2 5.1011 10.7225 2.2524 22.7134
SNU-1272 CTRP2 5.9241 12.2941 2.124 10.5984
TUHR10TKB CTRP2 6.0369 9.4206 3.618 4.3289
VMRC-RCZ CTRP2 6.4122 13.9179 1.6896 11.4838
RCC10RGB CTRP2; CTRP1 6.4441 8.3992 4.3529 1.1329
BFTC-909 CTRP2 6.5654 8.1772 4.4912 0.5789
A-498 CTRP2 6.8817 8.0292 4.6747 0.1017
KMRC-2 CTRP2 7.2638 8.6361 4.6026 0.1174
KMRC-1 CTRP2 7.3035 12.9989 2.7554 6.0127
786-O CTRP2 7.3414 8.7549 3.6395 0.029
OS-RC-2 CTRP2 7.4655 9.1573 4.4943 0.2164
769-P CTRP2 7.497 9.2392 4.477 0.2343
Caki-1 CTRP2 7.5325 9.8349 4.2704 0.6213
KMRC-20 CTRP2 7.7041 9.0568 4.6136 0.0542
ACHN CTRP2 7.733 9.2161 4.5703 0.083
Caki-2 CTRP2 9.0107 15.4508 2.6567 4.4579
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1033 CTRP2 0.6676 93.9901 -43.1265 48.1642
SW48 CTRP2; CTRP1 1.3892 3.9298 1.2963 24.7393
SNU-C4 CTRP1 1.7619 6.9003 0.8319 48.1615
HT115 CTRP2; CTRP1 2.945 6.6347 2.1897 16.8582
COLO 320 CTRP2; CTRP1 2.9984 10.2631 0.589 22.7298
HCT 8 CTRP2; CTRP1 2.9995 6.3327 2.3697 16.0164
GP2d CTRP2; CTRP1 3.0304 5.8512 2.5876 15.1006
LS513 CTRP2; CTRP1 3.1841 4.3599 3.1528 12.5837
NCI-H747 CTRP2 3.2518 7.3356 2.1986 15.9311
C2BBe1 CTRP2; CTRP1 3.3314 14.1128 -0.9777 26.7857
SNU-175 CTRP1 3.3793 15.3357 -1.5386 41.9811
SK-CO-1 CTRP2; CTRP1 3.5254 4.8699 3.4329 10.5259
KM12 CTRP2; CTRP1 3.7001 6.8931 2.8579 12.246
CW-2 CTRP2; CTRP1 3.8106 5.692 3.4834 9.5006
SNU-81 CTRP1 3.836 5.4314 3.6068 19.2325
CL-40 CTRP1 3.8985 5.3 3.7193 17.9454
SNU-C5 CTRP2; CTRP1 3.9657 5.5898 3.6881 8.286
NCI-H508 CTRP2; CTRP1 4.0957 8.172 2.6414 12.1691
SNU-407 CTRP2 4.2036 10.46 1.6075 16.0254
LS180 CTRP2; CTRP1 4.4011 6.2855 3.8376 6.5558
SNU-C1 CTRP2 4.4176 6.9786 3.5156 7.7476
HCT 116 CTRP2; CTRP1 4.4411 6.0941 3.9662 5.9374
LoVo CTRP2; CTRP1 4.5322 6.6589 3.7865 6.4535
RCM-1 [Human ESC] CTRP2; CTRP1 4.5514 6.0309 4.1047 5.1062
SNU-C2A CTRP2; CTRP1 4.6988 10.1455 2.2096 12.6337
SW1417 CTRP2 4.7586 9.5036 1.9164 8.4315
DLD-1 CTRP2; CTRP1 4.7939 5.6748 4.5095 2.8743
CL-34 CTRP1 4.8381 5.5548 4.6093 5.069
SW620 CTRP2; CTRP1 4.8714 6.0426 4.4032 3.1375
LS411N CTRP2; CTRP1 4.9013 5.8594 4.5207 2.5834
SW480 CTRP1 4.9584 7.7223 3.6425 13.114
HT-29 CTRP2; CTRP1 4.9992 5.7315 4.6716 1.7453
MDST8 CTRP2; CTRP1 5.0026 6.27 4.4058 2.8531
COLO 678 CTRP2; CTRP1 5.1336 9.6059 2.8473 9.1358
SNU-61 CTRP2; CTRP1 5.6431 10.8625 2.6284 9.112
SNU-1040 CTRP1 5.7308 10.6123 2.8204 16.5722
LS123 CTRP2; CTRP1 5.8445 8.5415 3.9209 3.4596
SW403 CTRP1 5.8527 9.5253 3.4477 11.3228
SW948 CTRP2; CTRP1 5.9359 46.2292 -14.8001 38.9055
SNU-503 CTRP2 6.1796 26.2019 -4.6038 30.9056
HCC-56 CTRP2 6.2227 7.4719 4.6156 0.449
CL-11 CTRP2 6.4913 14.5863 1.4191 12.3832
HT-55 CTRP2; CTRP1 6.5235 8.5327 4.3372 1.1177
LS1034 CTRP2 6.7597 9.2684 4.1325 1.5287
HCT 15 CTRP2 6.7963 8.5418 3.5238 0.1838
COLO205 CTRP2; CTRP1 6.9431 8.1434 4.6716 0.1137
RKO CTRP2; CTRP1 7.0562 8.3534 4.6397 0.1311
OUMS-23 CTRP2 7.2803 8.3465 4.7056 0.0321
NCI-H716 CTRP2 7.9786 9.734 4.4805 0.1335
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-1 CTRP2 2.5462 8.3452 1.0301 22.2565
HuH-6 CTRP2 3.2556 10.0568 0.9266 20.8157
HLF CTRP2 3.4709 5.0764 0.5504 0.2433
SNU-398 CTRP2; CTRP1 3.5893 4.8247 3.5124 10.0459
JHH-5 CTRP2 3.7449 6.3912 3.1201 11.0056
SNU-449 CTRP2; CTRP1 4.6143 7.3654 3.517 7.3864
Li-7 CTRP2 4.9835 12.9185 1.0565 16.5003
SNU-878 CTRP2 5.1486 6.6373 4.333 2.7951
SNU-761 CTRP2 5.1974 8.6879 2.6336 4.5619
PLC/PRF/5 CTRP2 5.4148 9.8273 2.9541 8.0905
JHH-1 CTRP2 6.0789 8.5634 4.0542 2.9357
Hep 3B2.1-7 CTRP2 6.3114 8.0224 3.5256 0.3098
SNU-182 CTRP2 6.5618 11.5298 2.9626 6.2088
SNU-423 CTRP2 6.6517 8.2052 3.588 0.1321
SNU-387 CTRP2 6.69 12.4941 2.5858 7.525
JHH-6 CTRP2; CTRP1 6.6929 7.5069 4.7998 0.0298
SNU-475 CTRP2 6.7744 8.0069 4.6429 0.1672
Hep-G2 CTRP2; CTRP1 6.933 8.0491 4.7005 0.0834
JHH-2 CTRP2 7.1459 10.4842 3.8118 2.2648
SK-HEP-1 CTRP2 7.3824 8.8501 4.5714 0.1324
JHH-4 CTRP2 7.4705 10.1741 4.1087 1.0684
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 154 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DMS 53 CTRP2 0.2189 6.3148 -0.6163 34.6742
SK-MES-1 CTRP2 0.7439 5.5176 0.2138 30.4195
NCI-H1792 CTRP2; CTRP1 1.5464 5.2837 1.1619 24.7167
DMS 454 CTRP2 1.5508 6.6932 0.6819 26.3229
NCI-H1963 CTRP1 1.722 3.5064 1.6958 47.732
T3M-10 CTRP2; CTRP1 1.7401 8.7525 0.0336 27.9828
NCI-H1573 CTRP2; CTRP1 1.848 11.1219 -0.9373 30.4823
COR-L279 CTRP2; CTRP1 1.9266 4.5353 1.7679 21.3928
NCI-H1568 CTRP2; CTRP1 2.126 5.1619 1.8294 20.5587
SHP-77 CTRP2; CTRP1 2.1405 4.5458 1.998 19.9133
LCLC-97TM1 CTRP2; CTRP1 2.1675 6.8841 1.2687 22.4961
VMRC-LCD CTRP2; CTRP1 2.4001 5.3447 2.0744 18.8447
LXF 289 CTRP2; CTRP1 2.4666 5.9833 1.9327 19.1734
NCI-H1373 CTRP2; CTRP1 2.4806 5.8347 2.0007 18.8795
NCI-H1048 CTRP1 2.5941 4.6791 2.4623 36.0696
SCLC-21H CTRP1 2.7595 5.3002 2.4797 34.687
NCI-H82 CTRP1 2.7704 4.4934 2.69 33.2518
EBC-1 CTRP2; CTRP1 2.8813 4.2754 2.8416 14.6275
HCC78 CTRP2; CTRP1 2.8962 4.4505 2.8327 14.6103
LUDLU-1 CTRP2 3.0014 8.254 1.5296 19.1866
COR-L88 CTRP1 3.081 4.4599 3.0295 28.6262
LC-1/sq-SF CTRP2; CTRP1 3.0839 5.1115 2.8889 13.8279
NCI-H1299 CTRP2; CTRP1 3.1905 5.7231 2.8065 13.8191
NCI-H1693 CTRP2 3.2064 7.5763 2.0443 16.6558
NCI-H2029 CTRP2; CTRP1 3.2343 8.7253 1.5478 18.6015
NCI-H3255 CTRP1 3.3326 7.6933 2.1245 32.6616
NCI-H810 CTRP2; CTRP1 3.3572 5.6799 3.0016 12.6081
NCI-H1930 CTRP1 3.4126 7.3101 2.3793 30.748
DMS 273 CTRP2; CTRP1 3.4182 5.0132 3.2807 11.3991
COLO 668 CTRP2; CTRP1 3.4738 7.8783 2.1798 15.5231
NCI-H2087 CTRP2 3.4982 14.7034 -1.1273 26.7475
NCI-H1435 CTRP2; CTRP1 3.5064 8.6419 1.8523 16.7427
NCI-H358 CTRP2; CTRP1 3.5247 8.3689 1.9995 16.1152
ChaGo-K-1 CTRP2; CTRP1 3.551 7.5064 2.4286 14.3377
NCI-H441 CTRP1 3.5591 6.6683 2.814 27.0299
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 3.5621 5.5128 3.2823 10.9663
HCC33 CTRP1 3.6577 5.194 3.4908 21.2751
Calu-6 CTRP2; CTRP1 3.6936 5.161 3.5398 9.628
EKVX CTRP2 3.7271 10.7817 1.0155 19.363
NCI-H1666 CTRP2; CTRP1 3.7561 4.923 3.6718 8.9623
NCI-H1944 CTRP2; CTRP1 3.7728 6.9262 2.9162 11.829
NCI-H2141 CTRP2; CTRP1 3.7729 5.0871 3.6477 8.9974
NCI-H1437 CTRP1 3.8206 8.4599 2.2414 29.1217
EPLC-272H CTRP2; CTRP1 3.9036 7.2618 2.8914 11.6045
NCI-H1838 CTRP2 3.904 8.3802 2.3516 13.7161
NCI-H2286 CTRP1 3.9275 5.6916 3.608 18.6618
HCC44 CTRP2; CTRP1 3.9308 9.0329 2.0681 14.8795
DV-90 CTRP2; CTRP1 3.9371 5.426 3.7179 8.2543
NCI-H1975 CTRP2; CTRP1 3.9427 5.9707 3.5107 9.0333
NCI-H2009 CTRP2; CTRP1 3.9947 7.5206 2.8582 11.5194
HCC4006 CTRP2; CTRP1 4.0242 5.8234 3.6573 8.2434
A-549 CTRP2; CTRP1 4.0579 6.7661 3.2747 9.6756
NCI-H1694 CTRP2; CTRP1 4.0719 5.5429 3.8195 7.4876
NCI-H2444 CTRP2 4.0909 6.2346 3.0168 4.7997
NCI-H2126 CTRP2; CTRP1 4.0993 8.6598 2.4073 13.1186
NCI-H2122 CTRP2; CTRP1 4.1082 8.5149 2.4863 12.7758
NCI-H596 CTRP1 4.2014 8.7954 2.4354 25.91
KNS-62 CTRP2; CTRP1 4.2131 7.2363 3.2044 9.5879
HCC2935 CTRP2; CTRP1 4.2968 5.4925 4.0787 5.8704
NCI-H2073 CTRP1 4.3124 10.3492 1.7685 29.0621
NCI-H211 CTRP2 4.3841 13.0027 0.5024 19.7404
NCI-H446 CTRP2 4.3979 5.5866 4.1418 5.2599
NCI-H2106 CTRP2 4.4207 9.1067 2.4726 12.0608
NCI-H1836 CTRP1 4.425 6.7264 3.6519 15.5401
SK-LU-1 CTRP2; CTRP1 4.4368 5.7691 4.1091 5.3767
Calu-3 CTRP2; CTRP1 4.4969 8.7994 2.7019 11.0295
NCI-H1155 CTRP2 4.5491 6.44 3.9005 5.858
NCI-H1395 CTRP2 4.5613 11.5529 0.7419 13.8373
HCC827 CTRP2; CTRP1 4.6085 5.4832 4.4103 3.7385
NCI-H1581 CTRP2 4.6305 7.0596 3.674 6.6123
NCI-H2170 CTRP2 4.633 7.5483 3.435 7.6029
NCI-H2081 CTRP2; CTRP1 4.6427 6.3271 4.0516 5.1071
NCI-H661 CTRP2; CTRP1 4.7352 6.663 3.9733 5.2239
NCI-H1355 CTRP2; CTRP1 4.7587 11.3521 1.6588 14.7205
NCI-H2405 CTRP2; CTRP1 4.7733 7.3454 3.6697 6.4088
HCC1195 CTRP2; CTRP1 4.8116 7.3857 3.6834 6.2711
HCC1438 CTRP2 4.8704 11.0115 1.9146 13.4032
COR-L51 CTRP2; CTRP1 4.8728 7.2991 3.7802 5.7394
NCI-H1092 CTRP2 4.9065 8.4189 2.5606 5.3387
NCI-H1876 CTRP1 4.9157 6.6042 4.1638 8.6789
BEN CTRP2; CTRP1 4.9167 6.5496 4.1919 3.9244
HCC2108 CTRP2; CTRP1 4.9243 6.3091 4.3184 3.3793
Lu-65 CTRP2; CTRP1 4.9483 6.5598 4.2144 3.7656
NCI-H1781 CTRP1 4.9535 6.3617 4.3177 7.1302
DMS 79 CTRP2 4.9594 10.1737 1.737 8.8546
NCI-H522 CTRP2; CTRP1 5.012 7.4663 3.8159 5.3109
HCC1359 CTRP1 5.0391 5.8128 4.6653 3.6298
NCI-H2172 CTRP1 5.0572 6.6233 4.2753 7.0692
LCLC-103H CTRP2; CTRP1 5.0704 6.5544 4.3207 3.0775
HOP-62 CTRP2 5.0766 9.2069 2.9899 8.5698
NCI-H2342 CTRP2; CTRP1 5.1199 10.978 2.15 12.0365
NCI-H727 CTRP2; CTRP1 5.1828 7.7544 3.8129 4.9981
NCI-H196 CTRP2 5.1898 11.33 2.022 12.3444
COR-L23 CTRP1 5.2027 6.3659 4.5211 4.2838
NCI-H1105 CTRP2; CTRP1 5.2242 7.788 3.8295 4.8526
CAL-12T CTRP2; CTRP1 5.2609 10.9254 2.2923 11.1874
NCI-H1915 CTRP2; CTRP1 5.391 13.8315 0.9461 16.1757
NCI-H650 CTRP2; CTRP1 5.4277 7.0544 4.3493 2.3394
PC-14 CTRP2 5.4469 7.6958 3.2507 1.7117
NCI-H520 CTRP2 5.4776 8.5446 3.6409 5.1144
RERF-LC-KJ CTRP1 5.4788 7.6851 4.0771 7.246
HCC1833 CTRP2; CTRP1 5.5157 11.5828 2.1693 11.2142
MOR/CPR CTRP2 5.5475 6.5967 3.7454 0.1561
NCI-H1563 CTRP2 5.5952 7.6431 4.1705 2.7365
NCI-H2228 CTRP2 5.6628 11.5517 1.5728 8.3705
NCI-H1703 CTRP2 5.7011 8.4941 3.0393 2.2398
NCI-H2030 CTRP2; CTRP1 5.7485 9.1386 3.5613 5.0769
COR-L105 CTRP2 5.7731 9.03 3.6214 4.7127
NCI-H838 CTRP2 5.8796 7.4075 3.5796 0.3623
NCI-H1793 CTRP2; CTRP1 5.8962 11.0549 2.7269 8.2736
RERF-LC-Ad1 CTRP2 5.9496 13.7363 1.4278 13.2787
LK2 CTRP2 6.0137 8.5727 4.0079 2.8024
NCI-H322 CTRP2 6.0776 10.3073 3.2164 5.9013
NCI-H1755 CTRP2; CTRP1 6.1466 9.2976 3.7632 3.6663
NCI-H1650 CTRP2 6.1517 10.8394 3.0099 6.6292
NCI-H292 CTRP2 6.1802 13.075 1.9319 10.9263
NCI-H226 CTRP2 6.2227 7.4767 3.6851 0.0952
NCI-H2023 CTRP2; CTRP1 6.2418 12.7044 2.1716 9.9469
COR-L95 CTRP2 6.3625 7.6587 3.6723 0.0879
NCI-H2110 CTRP2; CTRP1 6.4121 12.6496 2.3237 9.0659
COLO 699 CTRP2; CTRP1 6.4131 12.0552 2.615 7.8981
RERF-LC-A1 CTRP2 6.4646 8.3708 4.3625 1.0275
NCI-H1341 CTRP2 6.5271 8.0614 3.5929 0.1487
SBC-5 CTRP2 6.5378 7.5393 4.7199 0.1126
HCC1588 CTRP2 6.61 7.9196 3.67 0.0611
HCC95 CTRP2 6.6368 8.1794 4.5223 0.4607
NCI-H647 CTRP2 6.6637 14.9058 1.3895 12.2106
HCC366 CTRP2 6.7523 8.5539 4.4265 0.6412
HCC2279 CTRP2 6.7601 14.6458 0.8352 9.6829
Sq-1 CTRP2; CTRP1 6.7863 10.3689 3.668 3.2297
Calu-1 CTRP2 6.8513 9.7268 3.9823 1.9553
SW1271 CTRP2 6.9339 8.9056 3.4469 0.2622
RERF-LC-Ad2 CTRP2 6.9367 8.4365 4.5502 0.2758
NCI-H460 CTRP2; CTRP1 7.1015 11.4709 3.353 4.0482
NCI-H2196 CTRP2 7.1275 28.9058 -5.8882 27.3284
IA-LM CTRP2 7.1471 8.3401 4.6624 0.0745
LOU-NH91 CTRP2 7.1753 10.1559 3.97 1.7069
NCI-H2085 CTRP2 7.1765 9.187 4.3667 0.566
Lu-99 CTRP2; CTRP1 7.188 8.9621 4.4708 0.3715
NCI-H524 CTRP2 7.2821 31.3411 -6.2888 29.7678
NCI-H23 CTRP2; CTRP1 7.3152 16.4349 1.124 12.2213
NCI-H1339 CTRP2 7.3451 13.0186 2.7728 5.8925
NCI-H1184 CTRP2 7.5454 9.677 4.3358 0.473
HCC1171 CTRP2 7.703 13.9985 2.5415 6.3195
NCI-H1869 CTRP2 7.785 18.3772 0.5009 13.6143
NCI-H1651 CTRP2 7.9407 13.9798 2.6977 5.4493
HOP-92 CTRP2 8.008 15.7774 1.9011 15.2424
NCI-H1623 CTRP2 8.1027 17.1762 1.299 10.3828
NCI-H841 CTRP2; CTRP1 8.1445 19.6285 0.1578 14.2667
HCC15 CTRP2; CTRP1 8.2889 18.8803 0.6196 12.5381
RERF-LC-MS CTRP2 9.9047 20.7753 0.7661 9.8938
SW1573 CTRP2 11.3643 26.8262 -1.1378 13.8101
DMS 114 CTRP2 14.6971 40.4982 -5.4278 19.4668
Hs 888.Lu CTRP2 6.0428 11.6533 1.7838 6.9037
⏷ Show the Full List of 154 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 6.5865 7.711 4.6772 0.1635
P-STS CTRP2 7.108 8.7519 4.5025 0.3064
SYO-1 CTRP2 9.4691 19.5044 1.085 9.3615
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 7.0747 8.2872 4.655 0.0916
BT-16 CTRP2 3.1521 9.2683 1.204 20.0433
TE 441.T CTRP2 3.4985 5.2954 3.2827 11.0652
G-401 CTRP2; CTRP1 3.8086 7.6449 2.6183 12.9406
A-204 CTRP2 3.8259 6.7158 3.0587 11.0405
MES-SA CTRP2 4.1421 5.0829 4.0489 6.3387
TE 617.T CTRP2 4.2098 6.1409 3.7061 7.4754
Hs 729.T CTRP2 4.723 8.0818 3.2502 8.1851
HT-1080 CTRP2; CTRP1 5.0707 6.42 4.3882 2.7937
GCT CTRP2 5.2987 8.6268 3.4604 6.1827
RKN CTRP2; CTRP1 5.3381 6.6186 4.4977 1.8699
BT-12 CTRP2 6.0052 6.682 4.8242 0.0887
TTC-709 CTRP2 6.3905 9.0154 4.0369 2.2343
SK-LMS-1 CTRP2 6.653 11.9096 2.8423 6.558
SW982 CTRP2 6.8292 8.2903 4.5612 0.2926
Rh41 CTRP2 7.151 8.7734 4.5116 0.2758
G-402 CTRP2 7.2519 14.3477 2.0791 8.6888
KYM-1 CTRP2 7.2543 13.5516 2.4616 7.2119
Tm87-16 CTRP2 7.3193 13.9274 2.3258 7.6464
SK-UT-1 CTRP2 7.3283 8.9457 4.5178 0.2155
RD CTRP2 9.1932 17.9593 1.6297 7.8279
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.136 8.6842 4.5381 0.2352
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 7.9181 9.7491 4.4537 0.1737
TOV-21G CTRP2 -0.3315 1.4878 -0.5909 13.9693
SNU-119 CTRP2 1.5293 9.077 -0.3313 29.6532
OVCAR-4 CTRP2; CTRP1 2.8794 6.4054 2.2136 16.9465
JHOS-4 CTRP1 3.325 5.6202 2.9883 27.2694
RMUG-S CTRP1 3.3655 6.1152 2.844 28.0457
OVKATE CTRP1 3.8614 5.0787 3.7466 17.9688
OV-90 CTRP2; CTRP1 4.0787 5.9591 3.6573 8.097
OVMANA CTRP1 4.173 5.8312 3.8097 15.5554
Caov-3 CTRP2; CTRP1 4.1875 4.8989 4.1464 5.9406
A2780 CTRP1 4.1897 5.3479 4.0182 13.7413
JHOM-1 CTRP2; CTRP1 4.2312 5.1427 4.1314 5.8612
OVK18 CTRP2; CTRP1 4.3734 5.2641 4.2462 5.0187
OVCAR-8 CTRP2; CTRP1 4.5913 6.1962 4.0654 5.1709
OAW42 CTRP2; CTRP1 4.7142 6.0835 4.237 4.1788
TOV-112D CTRP2 4.7937 7.0431 3.8292 5.6134
RMG-I CTRP2; CTRP1 4.8094 9.9946 2.3801 11.7093
JHOC-5 CTRP2; CTRP1 4.89 6.123 4.3803 3.1931
IGROV-1 CTRP2; CTRP1 4.9321 7.4025 3.7798 5.6207
SNU-840 CTRP2; CTRP1 4.9404 8.0241 3.4764 6.8769
TYK-nu CTRP2; CTRP1 5.0052 8.251 3.4179 6.9948
SK-OV-3 CTRP2; CTRP1 5.0346 6.693 4.2215 3.5634
HEY A8 CTRP2; CTRP1 5.1488 6.9943 4.165 3.5838
OC 314 CTRP2 5.1963 7.5919 3.8949 4.5466
EFO-21 CTRP2; CTRP1 5.2208 6.693 4.3725 2.5846
OVCAR-5 CTRP2 5.2605 7.9498 3.7676 4.964
COV318 CTRP1 5.3925 6.3104 4.6845 2.2171
EFO-27 CTRP2; CTRP1 5.5063 7.054 4.4051 1.9932
OV7 CTRP2; CTRP1 5.6099 9.3623 3.3474 6.1909
COV434 CTRP2; CTRP1 6.2265 14.745 1.1512 13.8986
SNU-8 CTRP2 6.4414 7.7304 4.6113 0.3455
JHOS-2 CTRP2 6.4984 8.1215 3.5615 0.1972
OV56 CTRP2 6.5255 7.4531 4.7455 0.083
OVSAHO CTRP2 6.6364 8.0286 3.6426 0.08
OVISE CTRP2 6.6683 8.2888 4.4935 0.5154
COV644 CTRP2; CTRP1 6.8298 11.6616 3.0911 5.4005
DOV13 CTRP2 6.9137 8.2995 4.5911 0.2115
ES2 CTRP2 6.9764 8.1619 4.6629 0.0988
FU-OV-1 CTRP2 7.0629 9.4459 4.2114 1.0444
ONCO-DG-1 CTRP2 7.1334 8.816 4.489 0.323
OAW28 CTRP2 7.2078 10.6297 3.782 2.3092
Kuramochi CTRP2 7.3798 9.9709 4.1483 1.0156
COV362 CTRP2; CTRP1 7.4025 16.5223 1.1435 12.018
MCAS CTRP2 7.5307 9.0784 4.5459 0.1356
OVTOKO CTRP2 7.7284 9.9699 4.3012 0.4726
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2; CTRP1 0.7127 3.3068 0.6546 29.1219
NCI-H2052 CTRP2; CTRP1 4.338 5.8314 3.9804 6.143
NCI-H28 CTRP2; CTRP1 5.2423 10.9904 2.2445 11.4174
NCI-H2452 CTRP2 5.7818 8.7928 2.9518 2.4863
MPP 89 CTRP2 7.2431 8.7444 4.5572 0.1787
ACC-MESO-1 CTRP2 7.3347 8.4358 4.6945 0.0344
IST-Mes1 CTRP2 7.3364 12.2 3.1483 4.4751
JL-1 CTRP2 11.0362 21.0685 1.303 6.9472
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP2; CTRP1 3.6963 6.8415 2.8773 12.1783
LNCaP clone FGC CTRP2 4.7951 8.5996 3.055 8.8535
DU145 CTRP2 4.8733 8.7055 3.0694 8.6357
NCI-H660 CTRP2 5.1967 7.7761 3.8033 4.9302
VCaP CTRP2 5.3439 9.4809 2.3524 5.5448
22Rv1 CTRP2 7.0898 13.4454 2.402 7.6713
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 3.7882 8.6012 2.1349 14.8644
A-253 CTRP2 4.5058 8.734 2.7335 10.7987
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 CTRP2 2.692 5.0857 2.4657 16.4649
NUGC-4 CTRP2; CTRP1 2.9878 6.888 2.1285 16.9791
SNU-16 CTRP2 2.9882 4.3116 2.9498 13.8283
ECC10 CTRP2 3.0357 4.2691 3.0053 13.4849
IM95 CTRP2 3.1439 10.5208 0.5966 22.2726
NCC-StC-K140 CTRP2 3.5087 5.9876 3.0417 11.9463
HuG1-N CTRP2 3.5663 9.3848 0.9928 14.8933
Fu97 CTRP2; CTRP1 3.7654 16.1161 -1.5815 27.3656
NCI-N87 CTRP2 3.8622 11.2531 0.9071 19.4511
AGS CTRP2; CTRP1 3.9977 4.7979 3.9602 7.1911
SNU-719 CTRP2 4.529 8.0427 1.6549 4.1084
MKN7 CTRP2; CTRP1 4.5808 7.3799 3.4793 7.6163
Hs 746.T CTRP2 4.5872 6.0548 4.1214 4.8627
SNU-5 CTRP2 4.7042 10.0618 2.2468 12.3931
MKN74 CTRP2; CTRP1 4.9268 9.0995 2.9275 9.2033
SNU-216 CTRP2 5.169 18.2787 -1.4692 24.1122
MKN1 CTRP2 5.4171 7.494 4.1146 3.2451
KE-39 CTRP2 5.5579 10.0105 2.9753 7.749
SNU-620 CTRP2 5.8823 7.3272 4.5025 1.0803
GSU CTRP2 5.9446 6.6284 4.8202 0.1118
SNU-1 CTRP2 6.2842 8.0222 4.4176 0.9984
KATO III CTRP2 6.4646 10.9908 3.1553 5.5768
SH-10-TC CTRP2; CTRP1 6.4793 8.9637 4.1247 1.8854
MKN45 CTRP2 6.583 7.6385 4.7017 0.1275
ECC12 CTRP2 7.0431 8.4077 4.6016 0.1624
SNU-601 CTRP2 7.074 8.9679 4.4069 0.5208
SNU-668 CTRP2 7.1614 8.1931 4.7163 0.0343
NUGC-3 CTRP2 7.537 8.9784 4.5824 0.0967
23132/87 CTRP2 7.5945 8.9302 4.6185 0.0606
GSS CTRP2 7.759 36.591 -8.5276 31.8823
LMSU CTRP2 9.2219 18.0744 0.7676 6.8243
SNG-M CTRP2; CTRP1 4.9141 6.6615 4.134 4.1724
SNU-685 CTRP2 7.2483 8.4668 4.6548 0.0688
SNU-1077 CTRP2 7.4533 9.0127 4.5406 0.1561
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 5.0559 9.0298 3.0612 8.3108
BHT-101 CTRP2 5.495 10.3502 2.757 8.7661
FTC-133 CTRP2 5.9626 11.6864 2.4541 9.2007
8505C CTRP2 6.1667 8.6723 4.0586 2.4125
ML-1 [Human leukemia] CTRP2 6.3466 8.2235 3.4656 0.417
TT CTRP2 6.6506 11.9629 2.815 6.6703
FTC-238 CTRP2 6.9734 12.5811 2.737 6.524
CGTH-W-1 CTRP2 7.1239 8.6004 4.5635 0.1984
B-CPAP CTRP2 7.1345 8.7144 4.5266 0.2549
TT2609-C02 CTRP2 7.3888 15.1238 1.7994 9.5548
8305C CTRP2 7.4136 9.0615 4.5088 0.2079
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1214 CTRP2 1.0616 4.4099 0.8532 27.2448
YD-10B CTRP2 3.7163 7.5584 2.0338 10.01
PE/CA-PJ34 (clone C12) CTRP2 3.9811 7.1239 3.0251 10.7901
SNU-899 CTRP2 4.0715 7.8657 2.1851 8.5701
FaDu CTRP2 4.0931 6.9379 3.2224 9.7166
HSC-2 CTRP2; CTRP1 4.1717 5.3201 4.0086 6.4896
SCC-9 CTRP2; CTRP1 4.9058 6.3486 4.2824 3.5686
PE/CA-PJ49 CTRP2 5.3671 8.19 3.7318 4.9248
PE/CA-PJ15 CTRP2 5.3836 8.4853 3.5978 5.4566
HSC-3 CTRP2 5.7113 6.885 3.7046 0.1776
SCC-4 CTRP2 5.9345 8.4864 3.9967 2.9531
BICR 22 CTRP2 6.0497 7.5243 3.6045 0.2499
CAL-33 CTRP2 6.051 10.1688 3.2649 5.744
SCC-25 CTRP2 6.0745 14.6443 1.0736 14.3837
Detroit 562 CTRP2 6.136 7.7388 3.5602 0.304
BICR 18 CTRP2 6.2007 8.1785 3.4215 0.5848
BHY CTRP2 6.3016 10.883 3.0948 6.0572
BICR 16 CTRP2 6.4063 8.3273 4.3509 1.1132
PE/CA-PJ41 (clone D2) CTRP2 6.4629 12.4891 2.4278 8.4983
HSC-4 CTRP2 6.8193 9.4803 4.0726 1.6763
BICR 6 CTRP2 6.8276 8.283 4.5632 0.2892
CAL-27 CTRP2 6.8448 8.0002 4.6714 0.1123
SNU-1076 CTRP2 7.0256 8.0893 4.7048 0.0534
YD-8 CTRP2 7.1188 9.1581 4.3527 0.6285
BICR 31 CTRP2 7.1611 21.542 -2.2296 19.3354
BICR 56 CTRP2 7.2851 8.7536 4.5695 0.1531
SNU-1041 CTRP2 9.1382 16.0432 2.4657 4.986
SNU-1066 CTRP2 10.8733 22.6531 0.4931 9.6523
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-BLC1 CTRP2 1.333 2.3722 1.3326 24.7274
RT-4 CTRP2; CTRP1 2.3782 5.3669 2.0438 19.0219
5637 CTRP2; CTRP1 3.8023 5.215 3.642 8.9302
KMBC-2 CTRP2; CTRP1 4.352 5.4357 4.1596 5.4072
253J CTRP2 4.5382 6.9115 3.6615 6.8697
HT-1376 CTRP2; CTRP1 4.5529 6.6211 3.8244 6.2498
BC-3C CTRP2 4.7163 7.9736 3.2981 7.9986
UM-UC-3 CTRP2; CTRP1 4.9281 6.5583 4.1976 3.8774
253J-BV CTRP2 5.0671 8.2829 3.444 6.6829
UM-UC-1 CTRP2 5.3017 8.4464 3.5527 5.7905
BFTC-905 CTRP2 5.6281 7.9213 4.0586 3.1435
CAL-29 CTRP2 6.2798 8.6158 4.1529 1.9281
TCCSUP CTRP2 6.4902 8.2754 4.4155 0.8438
639V CTRP2 6.5082 7.7721 4.6236 0.2895
KU-19-19 CTRP2 6.6222 7.6987 4.6951 0.1278
647V CTRP2 6.8189 8.1418 4.6115 0.2052
JMSU-1 CTRP2 6.8914 8.1957 4.6199 0.1723
SW1710 CTRP2 7.0898 8.9765 4.4105 0.5053
RT-112 CTRP2 7.5119 9.1311 4.5207 0.1696
T24 CTRP2 7.7225 14.5203 2.3092 7.1713
VM-CUB-1 CTRP2 7.9034 9.3814 4.5734 0.0635
J82 CTRP2 8.2038 12.4604 3.5207 2.3063
SCaBER CTRP2 10.0921 19.1696 1.6129 6.895
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 6.5022 7.4551 4.7363 0.0985

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