Details of the Drug

General Information of Drug (ID: DMB4OFL)

Drug Name
Darinaparsin
Synonyms ZIO-101
Indication
Disease Entry ICD 11 Status REF
Hematologic tumour 2B33.Y Phase 2 [1]
Liver cancer 2C12 Phase 2 [1]
Multiple myeloma 2A83 Phase 2 [1]
Peripheral T-cell lymphoma 2A90.C Phase 2 [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C12H22AsN3O6S
Canonical SMILES
C[As](C)SCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N
InChI
1S/C12H22AsN3O6S/c1-13(2)23-6-8(11(20)15-5-10(18)19)16-9(17)4-3-7(14)12(21)22/h7-8H,3-6,14H2,1-2H3,(H,15,20)(H,16,17)(H,18,19)(H,21,22)/t7-,8-/m0/s1
InChIKey
JGDXFQORBMPJGR-YUMQZZPRSA-N
Cross-matching ID
PubChem CID
11683005
ChEBI ID
CHEBI:94295
CAS Number
69819-86-9
UNII
9XX54M675G
DrugBank ID
DB06179
TTD ID
D03ZME
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 89 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 6.9549 9.0724 4.3122 0.8284
SU-DHL-5 CTRP1 1.8426 2.4197 1.8426 45.9471
NCI-H929 CTRP2 2.3911 4.363 2.3023 17.9795
SUP-T11 CTRP2 2.5598 5.1021 2.3169 17.4042
SKM-1 CTRP2; CTRP1 3.0667 4.2089 3.0447 13.3334
ALL-SIL CTRP2 3.0759 5.0466 2.8955 13.7457
WSU-DLCL2 CTRP2; CTRP1 3.1329 4.189 3.1157 12.8768
JVM-2 CTRP2 3.3137 5.8154 2.9006 13.0303
EJM CTRP1 3.6166 5.5585 3.3248 22.8362
KMS-34 CTRP2 3.6191 4.4686 3.6002 9.5593
SU-DHL-1 CTRP2 3.8471 4.8701 3.7809 8.2051
L-1236 CTRP2 3.9508 8.9471 2.1206 14.5439
MOLM-13 CTRP2 3.9717 6.551 3.2804 9.7833
KMS-21-BM CTRP2 4.0194 6.4846 3.3586 9.3496
RCH-ACV CTRP2 4.0455 6.2163 3.5053 8.697
DEL CTRP2 4.1003 5.4534 3.8793 7.0913
NALM-6 CTRP2 4.2672 6.3842 3.6525 7.5468
OCI-AML-3 CTRP1 4.4126 6.8308 3.5899 16.1332
NU-DUL-1 CTRP2; CTRP1 4.4523 6.149 3.9519 5.9675
EM-2 CTRP2 4.5044 8.7375 2.7305 10.8142
MV4-11 CTRP2 4.51 6.9316 3.6254 7.0829
MHH-CALL-3 CTRP2 4.7874 6.9539 3.8679 5.4647
MHH-CALL-4 CTRP2 4.7921 5.9929 4.3463 3.4605
Ki-JK CTRP2 5.0367 7.0919 4.0142 4.3449
KE-37 CTRP2 5.0397 7.8215 3.652 5.8618
KMS-11 CTRP2 5.0593 6.3463 4.4058 2.6555
KMS-18 CTRP2 5.2224 7.0696 4.1761 3.3205
SU-DHL-4 CTRP2; CTRP1 5.2597 6.8079 4.3456 2.6296
Mono-Mac-1 CTRP2 5.299 8.4935 3.5271 5.9026
SK-MM-2 CTRP2 5.2997 7.6344 3.9555 4.1074
JVM-3 CTRP2 5.3441 9.1001 3.2606 6.9378
ME1 CTRP2 5.347 6.8574 4.3761 2.2762
SU-DHL-6 CTRP2 5.3548 7.2845 4.1713 3.1128
Ri-1 CTRP2 5.4743 7.7734 4.0195 3.5459
P12-Ichikawa CTRP2 5.5509 8.5016 3.7176 4.6721
P31/FUJ CTRP2 5.5958 8.2622 3.8687 3.974
RS4;11 CTRP2 5.6276 7.3816 4.3188 2.0907
MOLT-16 CTRP2 5.628 7.1414 4.4332 1.6367
U-937 CTRP2; CTRP1 5.6619 9.0393 3.5461 5.2801
KMS-26 CTRP2 5.6644 6.874 4.5801 1.0301
KMS-12-BM CTRP2 5.7029 8.4534 3.8527 3.872
OCI-AML-2 CTRP2 5.8203 7.594 4.3436 1.7419
THP-1 CTRP2; CTRP1 5.8591 8.4026 3.9978 3.1286
CML-T1 CTRP2 5.8608 7.6352 4.3496 1.6697
KMS-27 CTRP2 5.8701 8.0419 4.1653 2.3723
MM1.S CTRP2 5.996 8.7583 3.9081 3.2217
Ku812 CTRP2 6.0058 9.7013 3.4604 5.015
JURL-MK1 CTRP2 6.0129 8.9444 3.8305 3.5078
KM-H2 CTRP2 6.0495 8.3582 4.1314 2.276
Karpas-299 CTRP2 6.0712 8.5742 4.0442 2.5862
Peer CTRP2 6.0782 8.8353 3.9258 3.0408
MOLM-6 CTRP2 6.0865 7.9966 4.3197 1.5264
RPMI-8402 CTRP2 6.0915 8.7679 3.9663 2.8643
EHEB CTRP2 6.1022 8.3192 4.1821 2.0199
GDM-1 CTRP2; CTRP1 6.1173 8.9337 3.9166 3.0985
Reh CTRP2 6.1422 12.1284 2.3705 9.241
RPMI-8226 CTRP2; CTRP1 6.1668 9.2798 3.785 3.5522
NOMO-1 CTRP2; CTRP1 6.2177 9.0492 3.927 2.9279
MC116 CTRP2 6.2922 6.9482 4.8352 0.0302
HDLM-2 CTRP2 6.2963 8.1577 4.3657 1.1599
L-540 CTRP2 6.3053 8.0556 4.4144 0.9914
NB4 CTRP2 6.3278 7.7535 4.5512 0.5602
MOLP-2 CTRP2 6.4106 8.4648 4.2938 1.2991
KE-97 CTRP2 6.4726 10.4168 3.4349 4.4532
PF-382 CTRP2 6.4754 9.3343 3.9422 2.491
KYO-1 CTRP2 6.4854 8.4147 4.3546 1.0361
LAMA-84 CTRP2 6.5164 9.2363 4.011 2.1921
Raji CTRP2 6.5563 9.7281 3.8104 2.8924
HT CTRP2 6.6066 10.7418 3.3687 4.5355
KMM-1 CTRP2 6.6309 14.5698 1.5305 11.7336
KHM-1B CTRP2 6.6704 10.4898 3.5281 3.8329
MOLT-13 CTRP2 6.6814 8.4552 4.4333 0.6651
KCL-22 CTRP2 6.6872 8.5885 4.3821 0.8046
SU-DHL-8 CTRP2 6.7513 8.1795 4.5707 0.3026
REC-1 CTRP2 6.7774 11.3996 3.169 5.0933
TALL-1 [Human adult T-ALL] CTRP2 6.7956 9.5699 4.0206 1.8758
PL21 CTRP2; CTRP1 6.8077 10.807 3.4786 3.9235
BV-173 CTRP2 6.8505 8.309 4.5628 0.2819
HEL CTRP2 6.9183 8.1952 4.6301 0.1511
AMO1 CTRP2 6.9322 8.1516 4.6505 0.1212
Jurkat CTRP2 6.9535 8.6926 4.461 0.4528
Karpas-620 CTRP2 7.0309 8.248 4.6528 0.1008
SUP-T1 CTRP2 7.0463 8.4701 4.5806 0.1922
P3HR-1 CTRP2 7.0516 8.5175 4.5657 0.2141
SU-DHL-10 CTRP2 7.0535 7.9759 4.7516 0.0233
HPB-ALL CTRP2 7.0572 10.507 3.7521 2.5614
MOLM-16 CTRP2; CTRP1 7.2197 8.6777 4.5863 0.167
L-363 CTRP2 7.2363 8.4048 4.6715 0.057
SR CTRP2 7.4675 8.8494 4.6018 0.088
⏷ Show the Full List of 89 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 6.8115 11.352 3.2136 4.8741
COLO 680N CTRP2 6.254 8.9117 4.0018 2.5242
TE-6 CTRP2 7.1873 9.0435 4.426 0.4593
TE-10 CTRP2 7.4291 9.2663 4.441 0.3126
TE-1 CTRP2 7.4998 9.0974 4.5281 0.1627
KYSE-70 CTRP2 7.5109 9.3563 4.4403 0.2891
TE-4 CTRP2 7.6056 9.1621 4.5439 0.1253
TE-9 CTRP2 7.6492 8.8795 4.6536 0.0354
KYSE-410 CTRP2 7.7244 9.5607 4.4484 0.221
KYSE-180 CTRP2 7.9271 9.7389 4.4604 0.1641
KYSE-140 CTRP2 8.4452 10.2673 4.4628 0.0907
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-NB-11 CTRP2 5.1677 8.6215 3.3575 6.8555
Kelly CTRP2 6.6342 7.968 4.6019 0.2845
NB1 CTRP2 6.6582 8.266 4.4979 0.5096
KP-N-SI9s CTRP2 6.8391 8.1255 4.6251 0.1778
CHP-126 CTRP2 6.8933 9.7737 3.9848 1.9073
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 CTRP2 6.1472 7.5898 4.5308 0.7479
HuH-28 CTRP2 6.2067 9.4147 3.7354 3.6213
SNU-1196 CTRP2 6.6748 9.2209 4.1073 1.691
SNU-308 CTRP2 6.8288 8.3528 4.5376 0.3399
SNU-478 CTRP2 7.3086 9.0401 4.4762 0.2886
SNU-1079 CTRP2 7.8823 9.8872 4.3918 0.2652
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CADO-ES1 CTRP2 4.5394 6.9102 3.6632 6.86
U2OS CTRP2 6.1328 9.311 3.7357 3.7206
CAL-78 CTRP2 6.7796 8.5653 4.4344 0.605
SW1353 CTRP2 7.0167 8.9536 4.3875 0.5956
MHH-ES-1 CTRP2 7.2197 9.1173 4.4117 0.4458
SJSA-1 CTRP2 7.3408 9.1021 4.4662 0.296
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HDQ-P1 CTRP2 5.2912 6.9312 4.2979 2.6925
MCF-7 CTRP2; CTRP1 5.9893 7.8514 4.3407 1.6238
KPL-1 CTRP2 6.0024 7.231 4.6086 0.6174
CAL-148 CTRP2 6.5335 8.3986 4.3856 0.9026
JIMT-1 CTRP2 6.6076 8.0136 4.5736 0.3553
HCC1954 CTRP2 6.72 8.9671 4.2407 1.2098
CAL-120 CTRP2 6.8201 8.0758 4.6356 0.1666
ZR-75-1 CTRP2 6.8734 8.1887 4.6155 0.1835
HMC-1-8 CTRP2 6.9326 8.1529 4.6502 0.1215
CAMA-1 CTRP2 7.2982 8.9805 4.4938 0.2619
MDA-MB-231 CTRP2 7.326 9.3707 4.3602 0.5122
HCC1806 CTRP2 7.5443 9.0303 4.5673 0.1104
HCC1937 CTRP2 7.6657 9.5802 4.4192 0.2797
HCC1395 CTRP2 7.7895 9.5821 4.4649 0.1847
HCC1143 CTRP2 8.2105 10.3152 4.363 0.2299
CAL-51 CTRP2 8.2135 9.7491 4.5562 0.0497
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.7703 7.9526 4.6607 0.1421
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-489 CTRP2 5.2606 7.3873 4.0479 3.7893
SNU-466 CTRP2 5.3036 6.8109 4.3668 2.3853
CAS-1 CTRP2 5.3858 9.113 3.2872 6.7517
SNU-626 CTRP2 5.5496 8.3349 3.7988 4.3377
SNU-738 CTRP2 5.7685 7.7736 4.2258 2.2683
Daoy CTRP2 6.1536 8.8393 3.9725 2.7606
KNS-81 CTRP2 6.3802 7.7771 4.566 0.4887
KNS-60 CTRP2 6.385 7.5754 4.6465 0.2919
SNU-201 CTRP2 6.5235 8.4876 4.3432 1.0418
SF295 CTRP2 6.6269 8.007 4.5842 0.324
U-87MG ATCC CTRP2 6.6969 8.4372 4.4477 0.6175
SNU-1105 CTRP2 6.7094 7.7647 4.704 0.0984
NMC-G1 CTRP2 6.7436 8.22 4.5524 0.3435
DBTRG-05MG CTRP2 6.7943 8.5629 4.4419 0.5776
GB-1 CTRP2 6.8137 8.4085 4.5103 0.405
LN-18 CTRP2 6.8868 7.7342 4.7754 0.0216
LN-229 CTRP2; CTRP1 7.081 9.0241 4.4021 0.5696
AM-38 CTRP2 7.144 9.3616 4.2837 0.7913
ONS-76 CTRP2 7.1658 8.9493 4.4525 0.3824
GaMG CTRP2 7.3733 8.6473 4.6373 0.069
SW1088 CTRP2 7.4757 9.2186 4.4763 0.241
SF126 CTRP2 7.8306 9.094 4.6436 0.03
KALS-1 CTRP2 8.4173 10.2155 4.4705 0.0877
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KLE CTRP2 5.7444 7.9038 4.1476 2.6134
HEC-265 CTRP2 5.8467 12.054 2.1837 10.4927
HEC-108 CTRP2 6.6727 7.7147 4.7081 0.1004
HEC-6 CTRP2 6.8248 8.35 4.5371 0.3427
RL95-2 CTRP2 7.1893 8.514 4.618 0.1129
HEC-59 CTRP2 7.2012 8.6455 4.5765 0.1616
HEC-251 CTRP2 7.262 8.7116 4.5758 0.1499
HEC-1-B CTRP2 7.4336 9.006 4.5358 0.1663
HEC-151 CTRP2 7.5006 8.735 4.6515 0.047
HEC-50B CTRP2 7.7407 9.2077 4.5758 0.0777
JHUEM-2 CTRP2; CTRP1 7.7447 9.2002 4.594 0.0758
EFE-184 CTRP2 7.7963 9.1261 4.6217 0.0425
Ishikawa (Heraklio) 02 ER- CTRP2 6.3791 7.3878 4.7138 0.1626
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR4TKB CTRP2 4.9958 8.6962 3.1778 7.9386
VMRC-RCW CTRP2 6.4166 8.4174 4.3176 1.2141
BFTC-909 CTRP2 6.6065 8.0183 4.5714 0.3608
TUHR10TKB CTRP2 6.6821 8.1812 4.5412 0.3945
SNU-1272 CTRP2 6.7803 8.0797 4.619 0.2039
OS-RC-2 CTRP2 7.0945 9.4358 4.2307 0.9676
KMRC-20 CTRP2 7.166 8.8227 4.4995 0.2925
769-P CTRP2 7.6028 8.8766 4.6391 0.0465
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-C4 CTRP1 5.4894 6.5721 4.6239 2.4554
LS123 CTRP2; CTRP1 5.6225 7.1802 4.4232 1.7583
SW48 CTRP2 5.8447 8.1949 4.0759 2.7608
CCK-81 CTRP2 5.9631 8.2566 4.1242 2.4126
MDST8 CTRP2; CTRP1 6.5417 7.8485 4.6226 0.3143
SNU-C5 CTRP2; CTRP1 6.5802 9.3734 3.9988 2.2342
HCT 116 CTRP2; CTRP1 6.6275 7.8686 4.65 0.227
LS411N CTRP2 6.6353 7.9872 4.5952 0.2978
DLD-1 CTRP2 6.6482 7.563 4.7514 0.0583
SNU-175 CTRP1 6.686 8.8276 4.2956 2.401
COLO201 CTRP2 6.7068 8.2046 4.5428 0.38
SW1463 CTRP2 6.7136 8.4133 4.4648 0.5636
HCT 8 CTRP1 6.733 7.7736 4.7237 0.1946
SW480 CTRP1 6.7501 9.1476 4.1925 2.995
HT-29 CTRP2; CTRP1 6.85 7.99 4.6911 0.1077
SNU-81 CTRP1 6.8678 8.7709 4.4065 1.4446
OUMS-23 CTRP2 6.9072 8.0644 4.6717 0.1006
COLO 678 CTRP1 6.942 9.1092 4.3047 1.9455
SW948 CTRP1 6.977 8.471 4.5676 0.5618
CL-34 CTRP1 6.9925 8.5494 4.545 0.6402
SNU-61 CTRP2; CTRP1 7.0142 8.5124 4.5672 0.2508
RCM-1 [Human ESC] CTRP1 7.0267 8.3605 4.6264 0.3326
SK-CO-1 CTRP2 7.1504 8.7906 4.5051 0.2876
CL-11 CTRP2 7.2035 9.0366 4.4353 0.4028
HT115 CTRP2; CTRP1 7.2244 8.5224 4.6419 0.0993
SNU-1040 CTRP1 7.2291 8.6741 4.591 0.3402
COLO205 CTRP2 7.2965 8.6245 4.6182 0.0959
LS180 CTRP2 7.3644 8.7718 4.5919 0.1126
KM12 CTRP2; CTRP1 7.4055 8.9024 4.5759 0.1425
CL-40 CTRP1 7.4122 9.011 4.5403 0.4016
LS513 CTRP2 7.4494 8.8345 4.6005 0.0916
CW-2 CTRP2; CTRP1 7.4623 9.5797 4.3519 0.509
NCI-H508 CTRP2; CTRP1 7.5486 8.9 4.6272 0.0708
LoVo CTRP2; CTRP1 7.8642 9.7536 4.4465 0.2151
SW620 CTRP2; CTRP1 7.8937 9.3526 4.594 0.0614
COLO 320 CTRP1 7.8989 10.5273 4.1753 1.5166
HT-55 CTRP2; CTRP1 7.9749 8.994 4.7369 0.0057
RKO CTRP2; CTRP1 8.0591 9.5041 4.5996 0.0455
SNU-407 CTRP2 8.1906 9.7834 4.5372 0.0626
SNU-C2A CTRP2 8.2379 10.5123 4.3035 0.3083
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep-G2 CTRP2; CTRP1 4.6428 6.7902 3.826 6.0394
SNU-182 CTRP2 5.1096 8.2628 3.4892 6.4119
SNU-878 CTRP2 5.2732 7.5456 3.979 4.0556
Hep 3B2.1-7 CTRP2 7.094 8.3491 4.6406 0.1038
HuH-6 CTRP2 7.381 9.5513 4.3144 0.5906
SNU-761 CTRP2 7.4283 8.9812 4.5425 0.1587
SNU-398 CTRP2 7.4613 9.9163 4.2075 0.8101
SNU-886 CTRP2 7.7194 9.84 4.3457 0.3902
Li-7 CTRP2 7.9075 9.6432 4.4864 0.1385
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 96 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2106 CTRP2 2.5037 7.1242 1.5186 20.5515
NCI-H2342 CTRP1 4.305 6.4284 3.6763 15.9567
HCC1359 CTRP1 4.669 7.8776 3.3127 17.2058
NCI-H1876 CTRP1 4.7925 5.5966 4.5452 5.8651
NCI-H1694 CTRP1 4.7944 5.7403 4.4788 6.4371
HCC1195 CTRP2; CTRP1 4.9121 7.9202 3.5042 6.8171
NCI-H841 CTRP1 4.9662 6.0738 4.4722 5.6844
NCI-H1581 CTRP2 5.1169 8.4819 3.3857 6.833
COLO 699 CTRP2; CTRP1 5.1534 6.9188 4.2065 3.4013
NCI-H2081 CTRP1 5.5022 7.4615 4.204 6.0503
HCC2935 CTRP1 5.6085 7.8693 4.0812 6.7709
HCC4006 CTRP1 5.7003 7.7518 4.2022 5.4318
NCI-H1573 CTRP2 5.8336 8.1739 4.0785 2.7657
NCI-H446 CTRP2 5.8558 7.8998 4.2231 2.1643
NCI-H1155 CTRP2 5.9429 11.1168 2.7206 8.1464
DMS 79 CTRP2 6.02 7.6304 4.4454 1.1447
NCI-H358 CTRP2 6.0953 10.4747 3.1474 6.1557
HCC95 CTRP2 6.1034 7.7754 4.4278 1.1258
RERF-LC-Ad1 CTRP2 6.1609 6.8797 4.8123 0.0706
NCI-H1836 CTRP1 6.2249 9.2753 3.8252 7.0634
NCI-H2009 CTRP2 6.2257 9.0682 3.9112 2.9076
BEN CTRP2 6.2264 7.1477 4.7414 0.1619
NCI-H2110 CTRP1 6.2348 9.3788 3.7828 7.3811
LOU-NH91 CTRP2 6.2459 8.4779 4.1955 1.8089
SBC-5 CTRP2 6.2781 7.4361 4.6543 0.3226
Lu-99 CTRP2 6.3131 10.4769 3.299 5.2168
NCI-H69 CTRP2 6.3248 13.3683 1.8954 10.8288
NCI-H2444 CTRP2 6.337 7.4281 4.6821 0.2363
NCI-H1781 CTRP1 6.3478 8.7655 4.1377 4.2352
NCI-H526 CTRP2 6.4872 8.1172 4.479 0.6605
NCI-H650 CTRP2 6.5056 8.6212 4.2768 1.2716
MOR/CPR CTRP2 6.5362 7.3767 4.7754 0.0511
NCI-H596 CTRP1 6.5843 8.3381 4.4487 1.5727
HCC827 CTRP2; CTRP1 6.6329 8.4517 4.4255 0.7669
RERF-LC-A1 CTRP2 6.6508 9.2369 4.0871 1.7837
EBC-1 CTRP2 6.6951 8.6932 4.3429 0.9138
NCI-H2073 CTRP1 6.7224 9.6939 3.937 4.9215
NCI-H2030 CTRP2; CTRP1 6.762 8.4928 4.4688 0.571
NCI-H2126 CTRP2 6.7997 8.1586 4.5979 0.2344
NCI-H2286 CTRP2 6.8203 8.907 4.3156 0.907
NCI-H889 CTRP2 6.8263 8.6853 4.408 0.6474
COR-L23 CTRP1 6.8285 8.2331 4.596 0.556
SHP-77 CTRP2 6.9419 8.0203 4.6991 0.0677
Sq-1 CTRP2; CTRP1 7.0038 8.1977 4.6747 0.0995
NCI-H2228 CTRP2 7.0124 9.0918 4.331 0.7426
NCI-H1435 CTRP2 7.0229 9.0692 4.3448 0.7003
HCC15 CTRP2; CTRP1 7.0255 9.8513 4.0351 1.6791
HCC2108 CTRP2; CTRP1 7.0269 9.1177 4.341 0.7539
LCLC-103H CTRP2 7.0308 8.0735 4.7119 0.0477
NCI-H2172 CTRP2; CTRP1 7.0859 8.7707 4.5006 0.3506
NCI-H3255 CTRP1 7.0901 8.7727 4.5015 0.7451
NCI-H1755 CTRP2; CTRP1 7.0978 8.9649 4.4322 0.4913
NCI-H226 CTRP2 7.1379 8.4832 4.6101 0.1314
T3M-10 CTRP1 7.1718 9.452 4.2739 1.8168
NCI-H196 CTRP2 7.1783 8.6636 4.5616 0.1877
NCI-H1299 CTRP2 7.189 9.0573 4.4215 0.4375
CAL-12T CTRP2; CTRP1 7.2001 8.8418 4.52 0.2753
NCI-H1105 CTRP1 7.2091 8.803 4.5376 0.5214
NCI-H1838 CTRP2 7.215 8.9566 4.4698 0.3309
NCI-H460 CTRP2; CTRP1 7.229 8.2017 4.7504 0.0218
NCI-H2291 CTRP2 7.2553 9.3442 4.3401 0.5906
NCI-H292 CTRP2 7.27 9.0345 4.463 0.3248
NCI-H1734 CTRP2 7.2738 9.153 4.4206 0.4057
PC-14 CTRP2 7.2912 9.0275 4.474 0.2979
Calu-6 CTRP2 7.2969 9.0022 4.4854 0.2764
HCC44 CTRP2 7.3175 9.7542 4.2065 0.8951
HCC1588 CTRP2 7.3573 8.6606 4.6273 0.0792
Calu-3 CTRP2 7.3576 9.0763 4.4821 0.264
NCI-H727 CTRP2 7.3591 9.3003 4.4004 0.4137
NCI-H211 CTRP2 7.3701 13.4311 2.5947 6.5436
HARA [Human squamous cell lung carcinoma] CTRP2 7.3737 9.2737 4.4162 0.3771
HCC78 CTRP2 7.3924 9.2013 4.4503 0.3078
NCI-H1373 CTRP2 7.424 9.2745 4.436 0.3232
LCLC-97TM1 CTRP2 7.4301 9.2996 4.4293 0.3333
NCI-H2122 CTRP2; CTRP1 7.4528 8.705 4.6596 0.0564
SK-LU-1 CTRP2; CTRP1 7.4671 9.1559 4.5095 0.2182
NCI-H1666 CTRP2 7.4743 9.3003 4.4463 0.2898
HCC2279 CTRP2 7.4878 9.1603 4.5016 0.2006
NCI-H1792 CTRP2 7.4887 9.0826 4.5292 0.1635
HCC1833 CTRP2; CTRP1 7.5083 9.5358 4.3874 0.4174
HCC1171 CTRP2 7.5167 9.117 4.5274 0.1601
EPLC-272H CTRP2 7.5233 9.319 4.4585 0.2561
NCI-H2085 CTRP2 7.5239 9.4898 4.3966 0.3619
HCC366 CTRP2 7.543 9.4195 4.4298 0.2972
NCI-H2023 CTRP2; CTRP1 7.5751 9.6699 4.3646 0.4377
NCI-H441 CTRP2; CTRP1 7.5818 9.5913 4.3964 0.3741
NCI-H2087 CTRP2 7.6105 9.4216 4.4549 0.2389
NCI-H1355 CTRP2 7.6578 9.5065 4.4426 0.2455
NCI-H2405 CTRP2 7.6807 13.9863 2.5331 6.3794
NCI-H520 CTRP2 7.6964 9.3408 4.5149 0.1421
NCI-H1650 CTRP2 7.7396 9.5144 4.4703 0.188
LXF 289 CTRP2 7.8135 9.6956 4.4339 0.2208
SW1271 CTRP2 7.8608 9.7526 4.4314 0.2137
NCI-H661 CTRP2 7.8705 9.5766 4.4961 0.1341
NCI-H1184 CTRP2 7.9666 9.6412 4.5079 0.1086
A-549 CTRP2 8.2275 9.9338 4.4997 0.0851
⏷ Show the Full List of 96 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVK18 CTRP2; CTRP1 3.903 5.9506 3.4776 9.2692
EFO-27 CTRP1 4.2451 7.5167 3.0999 21.0102
COV434 CTRP1 4.3498 7.1832 3.3602 18.3827
A2780 CTRP2 4.5104 5.725 4.1975 4.7455
JHOM-1 CTRP1 4.6288 5.2033 4.5434 6.8035
OAW42 CTRP1 5.1302 6.009 4.6419 3.4738
OV7 CTRP1 6.3423 8.4888 4.2585 3.3199
ONCO-DG-1 CTRP2 6.3793 9.1559 3.9659 2.5122
SNU-8 CTRP2 6.458 7.576 4.6762 0.2044
SNU-119 CTRP2 6.8846 9.4572 4.1172 1.4719
OVISE CTRP2 6.9402 8.0931 4.6737 0.093
OVSAHO CTRP2 7.0287 8.3567 4.6142 0.1483
FU-OV-1 CTRP2 7.0597 8.7479 4.4844 0.3587
Caov-3 CTRP2; CTRP1 7.0625 8.3479 4.6439 0.1247
DOV13 CTRP2 7.0672 8.7619 4.4823 0.3602
ES2 CTRP2 7.1454 8.1639 4.7206 0.033
RMUG-S CTRP1 7.1646 11.751 3.2624 8.8932
TYK-nu CTRP2; CTRP1 7.2328 8.9648 4.4879 0.3226
OAW28 CTRP2 7.2525 9.6241 4.2286 0.8742
COV644 CTRP1 7.2648 8.888 4.5284 0.5198
HEY A8 CTRP2 7.3255 8.5421 4.6561 0.0594
SK-OV-3 CTRP2 7.3553 9.1822 4.4427 0.3336
JHOC-5 CTRP2; CTRP1 7.3751 8.8167 4.5946 0.1261
OVCAR-8 CTRP2 7.4444 9.0028 4.5408 0.1576
OV-90 CTRP1 7.5698 8.9516 4.6172 0.1642
COV362 CTRP1 7.5906 9.3698 4.4801 0.4965
Kuramochi CTRP2 7.7549 9.8366 4.361 0.3511
MCAS CTRP2 7.7752 9.1843 4.5954 0.06
SNU-840 CTRP2; CTRP1 7.8839 10.0401 4.3515 0.3572
OVCAR-4 CTRP2 7.8966 9.8781 4.4004 0.2489
IGROV-1 CTRP2 7.9426 9.7443 4.4642 0.1571
RMG-I CTRP2; CTRP1 8.1593 9.8459 4.5201 0.0892
OVTOKO CTRP2 8.2035 10.2448 4.3851 0.2031
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
QGP-1 CTRP2 4.07 22.7275 -4.6217 32.6395
KP-4 CTRP2 5.315 8.0826 3.7445 4.9636
SU.86.86 CTRP2 6.6767 7.7753 4.6884 0.1249
HuP-T4 CTRP2 6.8428 8.5344 4.4744 0.4735
SNU-410 CTRP2 6.9029 11.2881 3.3021 4.4146
SUIT-2 CTRP2 6.9613 8.886 4.3895 0.62
TCC-Pan2 CTRP2 6.9934 8.6 4.5126 0.3276
PaTu 8902 CTRP2 7.1253 8.5889 4.5682 0.191
SNU-213 CTRP2 7.1392 8.2991 4.6735 0.0659
L3.3 CTRP2 7.2407 8.7044 4.5704 0.1613
YAPC CTRP2 7.2586 8.2112 4.7425 0.0174
PK-59 CTRP2 7.3352 9.0753 4.4738 0.2846
Panc 05.04 CTRP2 7.4655 9.4617 4.3836 0.4073
BxPC-3 CTRP2 7.5266 9.409 4.4272 0.3065
HPAC CTRP2 7.5677 8.9853 4.5908 0.0852
KP-3 CTRP2 7.5845 9.936 4.2539 0.6351
CFPAC-1 CTRP2 7.5868 8.978 4.5999 0.0754
HPAF-II CTRP2 8.228 9.9888 4.4814 0.0996
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 CTRP2 5.7518 8.5881 3.8219 3.9236
ACC-MESO-1 CTRP2 6.0459 8.0051 4.292 1.6728
NCI-H2052 CTRP2 7.2513 9.1544 4.4108 0.4347
MSTO-211H CTRP2 7.7088 9.6238 4.42 0.2669
NCI-H2452 CTRP2 7.7378 9.6734 4.4133 0.2696
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 CTRP2 8.1161 9.8455 4.4909 0.1048
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 6.7417 7.6802 4.7443 0.053
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-7951 CTRP2 4.3328 5.9114 3.9337 6.2525
SK-MEL-28 CTRP2; CTRP1 6.4029 7.2348 4.791 0.0714
WM1799 CTRP2 6.4099 8.1533 4.4264 0.87
Mel Ho CTRP2 6.4816 8.8482 4.1646 1.6773
MDA-MB-435S CTRP2 6.5979 8.2053 4.4948 0.5507
Hs 852.T CTRP2 6.71 8.4884 4.4333 0.6481
SK-MEL-30 CTRP2 6.7344 7.99 4.6337 0.1928
G-361 CTRP2 6.7901 8.6185 4.4181 0.6417
IPC-298 CTRP2 6.8372 7.8976 4.704 0.0774
Hs 936.T CTRP2 6.8459 7.9716 4.6817 0.0999
SK-MEL-1 CTRP2; CTRP1 6.846 9.4037 4.1329 1.5115
SK-MEL-31 CTRP2 6.884 8.3977 4.5434 0.3072
WM793 CTRP2 6.9065 8.6511 4.4569 0.4841
SK-MEL-5 CTRP2; CTRP1 6.9713 8.3445 4.6112 0.1906
A-375 CTRP2; CTRP1 6.979 8.7049 4.481 0.4351
LOX-IMVI CTRP2 7.202 8.6161 4.5871 0.1475
Mel JuSo CTRP2 7.2793 8.6814 4.5925 0.1262
Hs 944.T CTRP2 7.5097 9.1603 4.5097 0.1845
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Rh41 CTRP2 3.8025 5.2083 3.641 8.8456
RKN CTRP2 7.0578 8.3846 4.6152 0.1409
HT-1080 CTRP1 7.0801 8.4628 4.6102 0.3549
Rh18 CTRP2 7.3939 8.7399 4.6132 0.0872
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 CTRP2 5.0963 6.4607 4.379 2.6982
MKN1 CTRP2 5.7093 10.7063 2.7467 8.4328
GSU CTRP2 5.737 6.3781 4.8289 0.1731
GSS CTRP2 6.2333 7.6596 4.5444 0.6425
NCI-N87 CTRP2 6.3262 8.079 4.4152 0.9713
23132/87 CTRP2 6.37 8.2107 4.3818 1.0432
ECC12 CTRP2 6.4807 7.8403 4.5858 0.3861
MKN45 CTRP2 6.5924 7.4667 4.7645 0.0537
SNU-5 CTRP2 6.8136 8.1623 4.602 0.2228
SNU-668 CTRP2 6.9154 8.0456 4.6811 0.089
AGS CTRP2 7.0045 8.3441 4.6097 0.1599
SNU-620 CTRP2 7.0927 8.2692 4.6675 0.0769
Fu97 CTRP2 7.3667 9.3219 4.3955 0.4208
NUGC-3 CTRP2 7.495 8.9357 4.5821 0.1028
OCUM-1 CTRP2 7.6066 9.2752 4.5051 0.1704
SNU-719 CTRP2 7.6132 9.4962 4.4292 0.2781
NUGC-4 CTRP2 7.7505 9.247 4.5659 0.0846
MKN74 CTRP2 8.2876 10.0855 4.4695 0.1026
KE-39 CTRP2 8.303 10.5968 4.298 0.3001
SNU-1077 CTRP2 7.1269 8.8615 4.4695 0.3633
SNG-M CTRP2 7.6215 9.103 4.5697 0.0972
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
B-CPAP CTRP2 4.5624 8.7911 2.7556 10.5866
8305C CTRP2 5.6226 9.1107 3.4707 5.5788
CGTH-W-1 CTRP2 5.8405 8.8149 3.7743 3.9836
CAL-62 CTRP2 6.2373 7.8112 4.4832 0.8266
8505C CTRP2 6.4383 8.8124 4.1561 1.7502
ML-1 [Human leukemia] CTRP2 6.8278 8.6952 4.4047 0.6551
BHT-101 CTRP2 7.2929 8.8034 4.555 0.1707
TT CTRP2 7.6982 9.0647 4.609 0.0577
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BHY CTRP2 5.8332 8.0635 4.1308 2.5579
SNU-1076 CTRP2 6.0665 8.7813 3.9436 2.9859
YD-10B CTRP2 6.5804 7.8529 4.6229 0.2629
HSC-3 CTRP2 6.6413 8.1089 4.5515 0.3899
SNU-46 CTRP2 6.6937 9.3431 4.0641 1.8225
SCC-25 CTRP2 7.2029 9.0308 4.4373 0.3992
YD-8 CTRP2 7.255 8.7559 4.5576 0.1755
HSC-4 CTRP2 7.2603 8.5781 4.6213 0.0981
SNU-899 CTRP2 7.3252 8.4746 4.6785 0.0442
SNU-1041 CTRP2 7.3786 8.992 4.5203 0.1996
SNU-1214 CTRP2 7.3881 9.6137 4.2934 0.6363
SNU-1066 CTRP2 7.8193 9.1102 4.6345 0.0346
Detroit 562 CTRP2 7.8446 9.806 4.4065 0.2527
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J CTRP2 5.1879 6.4056 4.4794 2.112
JMSU-1 CTRP2 5.4609 8.1619 3.8177 4.4061
BFTC-905 CTRP2 5.5973 6.9386 4.5089 1.3807
253J-BV CTRP2 5.7517 7.5942 4.2998 1.9991
CAL-29 CTRP2 5.963 7.6984 4.3823 1.4309
639V CTRP2 6.5405 7.5945 4.7014 0.1383
TCCSUP CTRP2 6.6742 8.7218 4.3207 0.9958
5637 CTRP2 6.9599 8.9043 4.3816 0.6407
KU-19-19 CTRP2 7.0308 8.3645 4.6123 0.1505
SW1710 CTRP2 7.2565 8.9129 4.5021 0.2601
RT-112 CTRP2 7.2615 8.6789 4.5869 0.1361
VM-CUB-1 CTRP2 7.312 8.9357 4.5152 0.2237
UM-UC-3 CTRP2 7.3916 8.8869 4.562 0.1418
RT-4 CTRP2 7.6535 9.2327 4.5367 0.1253
HT-1376 CTRP2 8.1351 9.7004 4.546 0.0616
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 6.2872 7.4215 4.6638 0.2966

References

1 ClinicalTrials.gov (NCT00421213) Phase II Study of ZIO-101 in Advanced Blood and Bone Marrow Cancers. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)