Details of the Drug

General Information of Drug (ID: DMB91UL)

Drug Name

morphanthridine

Synonyms

MORPHANTHRIDINE; 11H-Dibenz[b,e]azepine; 11H-dibenzo[b,e]azepine; 256-86-0; CHEMBL1085101; Homoacridan; 11H-benzo[c][1]benzazepine; SCHEMBL1150250; GTPL6473; CTK1A3708; DTXSID00446803; IDWNSAXOQLJYOF-UHFFFAOYSA-N

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

193.24

Logarithm of the Partition Coefficient (xlogp)

3

Rotatable Bond Count (rotbonds)

0

Hydrogen Bond Donor Count (hbonddonor)

0

Hydrogen Bond Acceptor Count (hbondacc)

1

Chemical Identifiers

Formula: C14H11N
IUPAC Name: 11H-benzo[c][1]benzazepine
Canonical SMILES: C1C2=CC=CC=C2C=NC3=CC=CC=C31
InChI: InChI=1S/C14H11N/c1-2-7-13-10-15-14-8-4-3-6-12(14)9-11(13)5-1/h1-8,10H,9H2
InChIKey: IDWNSAXOQLJYOF-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 10878016
CAS Number: 256-86-0
TTD ID: D01RUO

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Transformation-sensitive protein p120 (TRPA1)	TTELV3W	TRPA1_HUMAN	Activator	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6473).
2	Tear gasses CN, CR, and CS are potent activators of the human TRPA1 receptor. Toxicol Appl Pharmacol. 2008 Sep 1;231(2):150-6.