Details of the Drug

General Information of Drug (ID: DMBGM88)

Drug Name

LTI-03

Synonyms

CSP7; UNII-JE7G34JYW4; CSP-7; JE7G34JYW4; LTI-03; Phe-Thr-Thr-Phe-Thr-Val-Thr; L-Threonine, L-phenylalanyl-L-threonyl-L-threonyl-L-phenylalanyl-L-threonyl-L-valyl-; 1504575-10-3

Indication

Disease Entry	ICD 11	Status	REF
Idiopathic pulmonary fibrosis	CB03.4	Phase 1	[1]
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Drug Type

Peptide

Structure

3D MOL is unavailable

2D MOL

Chemical Identifiers

Formula: C39H57N7O12
Canonical SMILES: CC(C)C(C(=O)NC(C(C)O)C(=O)O)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)C(C(C)O)NC(=O)C(CC2=CC=CC=C2)N
InChI: InChI=1S/C39H57N7O12/c1-19(2)28(35(53)46-32(23(6)50)39(57)58)42-37(55)31(22(5)49)44-34(52)27(18-25-15-11-8-12-16-25)41-36(54)29(20(3)47)45-38(56)30(21(4)48)43-33(51)26(40)17-24-13-9-7-10-14-24/h7-16,19-23,26-32,47-50H,17-18,40H2,1-6H3,(H,41,54)(H,42,55)(H,43,51)(H,44,52)(H,45,56)(H,46,53)(H,57,58)/t20-,21-,22-,23-,26+,27+,28+,29+,30+,31+,32+/m1/s1
InChIKey: MPQBITKUSWZKQD-DVPOGPKQSA-N

Cross-matching ID

PubChem CID: 86268043
UNII: JE7G34JYW4
DrugBank ID: DB18491
TTD ID: D3C9RJ

References

1	ClinicalTrials.gov (NCT04233814) A Randomized, Double-Blind, Placebo-Controlled, Ph 1a, First-in-Man, Single Ascending Dose & Multiple Ascending Dose Safety, Tolerability and PK Study of a Caveolin-1-Scaffolding-Protein-Derived Peptide (LTI-03) in Healthy Adult Subjects. U.S.National Institutes of Health.