Details of the Drug

General Information of Drug (ID: DMBL7CW)

Drug Name
PRT-062607
Synonyms P-14276; P-505-15; Syk tyrosine kinase inhibitors (oral, cancers/inflammatory diseases/thrombosis), Portola
Indication
Disease Entry ICD 11 Status REF
Chronic lymphocytic leukaemia 2A82.0 Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 393.4
Logarithm of the Partition Coefficient (xlogp) 2.2
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 4
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C19H23N9O
IUPAC Name
2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[3-(triazol-2-yl)anilino]pyrimidine-5-carboxamide
Canonical SMILES
C1CC[C@H]([C@H](C1)N)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)N4N=CC=N4)C(=O)N
InChI
InChI=1S/C19H23N9O/c20-15-6-1-2-7-16(15)26-19-22-11-14(17(21)29)18(27-19)25-12-4-3-5-13(10-12)28-23-8-9-24-28/h3-5,8-11,15-16H,1-2,6-7,20H2,(H2,21,29)(H2,22,25,26,27)/t15-,16+/m0/s1
InChIKey
TXGKRVFSSHPBAJ-JKSUJKDBSA-N
Cross-matching ID
PubChem CID
44462758
CAS Number
1370261-96-3
TTD ID
D0R9IU

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tyrosine-protein kinase SYK (SYK) TTOU65C KSYK_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Chronic lymphocytic leukaemia
ICD Disease Classification 2A82.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tyrosine-protein kinase SYK (SYK) DTT SYK 5.20E-02 -0.57 -0.67
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 3.8685 6.433 2.1951 5.6926
EW-12 GDSC2 1.3031 3.4075 1.0948 21.3588
NOS-1 [Human HNSCC] GDSC2 1.7786 3.4299 1.607 16.397
ES5 GDSC2 2.0104 3.8854 1.7051 14.8287
SK-PN-DW GDSC2 2.1815 3.8877 1.8873 13.0592
EW-3 GDSC2 2.2141 4.2964 1.7561 13.6889
SaOS-2 GDSC2 2.3121 3.802 2.0596 11.5179
EW-11 GDSC2 2.4825 7.2926 0.5999 19.5037
ES8 GDSC2 2.485 10.118 -0.7965 26.1838
CHSA0011 GDSC2 2.5933 5.615 1.5231 13.6842
EW-7 GDSC2 2.6298 3.8972 2.3578 8.4697
ES6 GDSC2 2.7581 7.0573 0.9658 16.4822
HuO9 GDSC2 2.8541 6.1251 1.5137 12.8606
SK-ES-1 GDSC2 2.8931 5.9519 1.6345 11.9849
TC-71 GDSC2 2.9033 4.908 2.1578 8.6851
EW-22 GDSC2 2.9234 4.9162 2.1725 8.5254
A-673 GDSC2 3.0591 4.7741 2.3667 6.8582
EW-16 GDSC2 3.0788 7.0921 1.2306 13.8758
EW-1 GDSC2 3.0884 8.8196 0.3761 18.7215
EW-18 GDSC2 3.1406 5.044 2.3054 6.9833
EW-24 GDSC2 3.1927 4.7008 2.522 5.453
MHH-ES-1 GDSC2 3.3985 6.2547 1.9189 8.6571
CAL-72 GDSC2 3.4291 9.0312 0.5561 16.7148
CHSA0108 GDSC2 3.4671 5.9965 2.1036 7.3002
U2OS GDSC2 3.6029 6.8142 1.8041 8.8107
NY GDSC2 3.7303 10.7623 -0.0636 19.0453
CHSA8926 GDSC2 3.7461 9.9208 0.369 16.8086
H-EMC-SS GDSC2 3.8255 7.3471 1.712 8.7964
MG-63 GDSC2 3.8984 13.358 -1.2241 23.5696
U-CH2 GDSC2 3.9294 6.1459 2.3786 4.4205
HOS GDSC2 4.0486 6.6728 2.2066 5.2061
ES7 GDSC2 4.2703 7.0571 2.1733 4.9309
HuO-3N1 GDSC2 4.2806 11.3881 0.0573 16.9554
CADO-ES1 GDSC2 4.3972 11.3848 0.1478 16.2027
CAL-78 GDSC2 4.9785 12.7005 -0.0687 15.8357
ES4 GDSC2 4.9834 11.7981 0.3761 13.6157
EW-13 GDSC2 5.0229 6.8357 2.6992 0.9916
G-292 clone A141B1 GDSC2 5.3896 16.8541 -1.8078 21.9664
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 157 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 3.6346 5.5649 2.4492 4.6805
SU-DHL-5 GDSC2 -0.9296 0.7987 -0.9366 42.6939
RCH-ACV GDSC2 -0.7529 4.0784 -1.3525 42.6394
NALM-6 GDSC2 -0.5751 5.3096 -1.601 42.0912
JVM-3 GDSC2 -0.5411 4.6152 -1.3064 41.2305
SUP-B8 GDSC2 -0.3996 0.9938 -0.4032 37.3635
SU-DHL-6 GDSC2 -0.1818 1.721 -0.2116 35.3063
SU-DHL-4 GDSC2 -0.1387 1.4048 -0.1488 34.7783
SU-DHL-16 GDSC2 -0.0439 1.3029 -0.0489 33.8015
BONNA-12 GDSC2 -0.0236 3.5605 -0.397 35.2728
GA-10 GDSC2 0.1725 4.1244 -0.3635 34.0901
Kasumi-1 GDSC2 0.1752 1.8315 0.1524 31.6922
CTV-1 GDSC2 0.2764 3.1936 0.0324 31.7705
Namalwa GDSC2 0.2853 6.0758 -1.0053 35.8909
JVM-2 GDSC2 0.3594 5.6259 -0.7387 34.6028
MOLM-16 GDSC2 0.5193 2.328 0.4664 28.393
RPMI-6666 GDSC2 0.5325 9.3632 -2.2514 38.079
MOLM-13 GDSC2 0.5637 2.2105 0.5269 27.8655
Farage GDSC2 0.8102 4.4425 0.2101 28.3067
EoL-1 GDSC2 0.8257 3.224 0.6238 26.0983
MLMA GDSC2 0.8696 6.0446 -0.3885 30.8009
DoHH2 GDSC2 0.9432 1.6575 0.9428 23.8726
WSU-NHL GDSC2 1.1189 1.9848 1.116 22.1224
NU-DUL-1 GDSC2 1.2247 3.3508 1.0252 22.0957
L-1236 GDSC2 1.2278 6.1763 -0.0825 27.8566
OCI-AML-3 GDSC2 1.2955 3.72 0.9902 21.9647
DEL GDSC2 1.3761 2.22 1.3713 19.5505
P32/ISH GDSC2 1.404 2.862 1.3341 19.6067
RPMI-8866 GDSC2 1.4283 5.1265 0.5862 23.6122
KY821 GDSC2 1.4643 3.4957 1.2447 19.8073
NB4 GDSC2 1.4755 3.352 1.2986 19.4616
THP-1 GDSC2 1.4793 3.6221 1.2216 19.8668
CESS GDSC2 1.4821 4.6228 0.8537 21.9111
Karpas-299 GDSC2 1.4824 2.6407 1.4511 18.6194
GDM-1 GDSC2 1.5313 5.3626 0.5894 23.1653
ALL-PO GDSC2 1.5662 7.9728 -0.5906 28.6964
ML-2 GDSC2 1.5663 2.6879 1.5346 17.7794
SR GDSC2 1.5861 2.864 1.5301 17.707
JeKo-1 GDSC2 1.6025 4.0142 1.2195 19.337
AMO1 GDSC2 1.6358 3.3824 1.465 17.8231
P30/OHK GDSC2 1.661 8.8447 -0.9218 29.6319
Jiyoye GDSC2 1.6665 8.3012 -0.6532 28.5599
KMS-11 GDSC2 1.6979 3.841 1.3849 17.9912
BC-1 GDSC2 1.7035 3.0381 1.6243 16.651
A4/Fukuda GDSC2 1.7256 2.9821 1.6595 16.3606
OCI-Ly7 GDSC2 1.733 3.9953 1.3666 17.9431
A3/Kawakami GDSC2 1.7343 3.6356 1.4945 17.2181
VL51 GDSC2 1.7428 5.5905 0.7022 21.6868
Karpas-1106P GDSC2 1.7933 3.1083 1.7068 15.7897
PL-21 GDSC2 1.8128 3.7678 1.5348 16.647
Karpas-45 GDSC2 1.8275 3.6121 1.6034 16.1983
LAMA-84 GDSC2 1.8405 6.2437 0.4971 22.4267
MOLP-8 GDSC2 1.8514 3.7582 1.5799 16.2249
Loucy GDSC2 1.8718 3.0172 1.8109 14.8666
CRO-AP2 GDSC2 1.8959 3.1687 1.8046 14.7866
CTB-1 GDSC2 1.9055 4.648 1.2857 17.6927
MEG-01 GDSC2 1.9101 3.2884 1.7901 14.7988
L-363 GDSC2 1.9121 6.4514 0.4691 22.3006
ST486 GDSC2 1.9232 3.5381 1.7314 15.061
VAL GDSC2 1.9253 7.5948 -0.0666 24.9732
MHH-CALL-4 GDSC2 1.9415 3.7342 1.6856 15.2367
ARH-77 GDSC2 1.9572 4.8548 1.2493 17.6986
SU-DHL-1 GDSC2 1.973 3.709 1.7285 14.858
JURL-MK1 GDSC2 1.9746 4.1684 1.5573 15.8297
SIG-M5 GDSC2 2.031 3.3927 1.8931 13.6847
MHH-CALL-2 GDSC2 2.0583 4.0198 1.705 14.6271
697 GDSC2 2.0612 5.2273 1.1874 17.6563
TALL-1 [Human adult T-ALL] GDSC2 2.0995 3.4492 1.951 13.0569
SUP-M2 GDSC2 2.1 3.2487 2.0076 12.7464
Karpas-422 GDSC2 2.1169 3.4968 1.9552 12.9557
L-540 GDSC2 2.118 3.1854 2.0427 12.4743
Karpas-620 GDSC2 2.1434 3.4595 1.9957 12.6132
SKM-1 GDSC2 2.1507 3.6415 1.9442 12.8682
Daudi GDSC2 2.1579 4.4747 1.6215 14.7087
MM1.S GDSC2 2.1681 3.3244 2.0621 12.1373
KMS-12-BM GDSC2 2.1761 3.8809 1.8842 13.1003
MC116 GDSC2 2.2176 3.4367 2.0836 11.795
HAL-01 GDSC2 2.223 4.4136 1.7152 13.8954
DND-41 GDSC2 2.2354 3.6148 2.045 11.9313
OPM-2 GDSC2 2.2563 3.4227 2.13 11.3651
RPMI-8226 GDSC2 2.2582 4.7513 1.6019 14.4326
SUP-HD1 GDSC2 2.2613 11.6307 -1.7464 30.3142
BE-13 GDSC2 2.3726 3.7556 2.1419 10.7894
CML-T1 GDSC2 2.4299 3.6975 2.2252 10.0694
HT GDSC2 2.4351 4.709 1.7991 12.5716
NCI-H929 GDSC2 2.4484 3.5572 2.2953 9.5922
SU-DHL-10 GDSC2 2.4645 3.4319 2.354 9.194
U-698-M GDSC2 2.4901 3.7451 2.2716 9.5479
BL-41 GDSC2 2.4995 3.2621 2.44 8.5646
OCI-AML-2 GDSC2 2.5371 4.9915 1.7681 12.3827
P12-Ichikawa GDSC2 2.5519 4.616 1.9584 11.1676
RL GDSC2 2.5658 4.0622 2.2211 9.5341
PF-382 GDSC2 2.5688 4.3701 2.0878 10.3199
IM-9 GDSC2 2.5772 4.5479 2.015 10.7291
CCRF-CEM GDSC2 2.6764 4.1554 2.2934 8.6697
H9 GDSC2 2.699 4.3157 2.2433 8.8865
OCI-Ly19 GDSC2 2.7084 6.9319 0.9831 16.5458
MOLT-16 GDSC2 2.7162 4.0428 2.3841 7.9712
NK-92MI GDSC2 2.7466 3.6692 2.5741 6.7273
EB2 GDSC2 2.7699 6.3125 1.3449 14.1737
HEL GDSC2 2.7703 4.5821 2.1887 8.9579
SCC-3 GDSC2 2.8634 3.561 2.7407 5.2757
GR-ST GDSC2 2.911 6.1251 1.5647 12.3596
BALL-1 GDSC2 2.9357 5.8864 1.7052 11.4068
QIMR-WIL GDSC2 2.9646 5.8195 1.7642 10.9456
Ku812 GDSC2 3.0445 4.6557 2.4118 6.6231
SUP-T1 GDSC2 3.0731 5.1172 2.2093 7.8026
BC-3 GDSC2 3.0874 4.3631 2.595 5.3332
CA46 GDSC2 3.125 6.7022 1.465 12.302
MY-M12 GDSC2 3.2091 5.4911 2.1419 7.8049
Raji GDSC2 3.2353 7.0966 1.3619 12.5998
HL-60 GDSC2 3.2733 5.4828 2.2007 7.2412
KE-37 GDSC2 3.2758 4.6316 2.6282 4.528
Reh GDSC2 3.3215 5.5759 2.1946 7.1383
OCI-AML-5 GDSC2 3.3716 6.5642 1.742 9.8451
OCI-M1 GDSC2 3.3754 4.7785 2.6377 4.179
MOLT-13 GDSC2 3.4088 5.8715 2.1188 7.3675
Ramos.2G6.4C10 GDSC2 3.4126 5.415 2.35 5.8949
TUR GDSC2 3.413 5.3444 2.3855 5.669
MN-60 GDSC2 3.415 5.0435 2.5374 4.7035
MHH-PREB-1 GDSC2 3.4584 4.907 2.6401 3.9362
ALL-SIL GDSC2 3.4689 5.4537 2.376 5.5753
Jurkat GDSC2 3.551 5.3867 2.4737 4.7403
ME1 GDSC2 3.5846 5.2565 2.5639 4.088
HC-1 GDSC2 3.5993 6.4782 1.9686 7.7905
JSC-1 GDSC2 3.6008 6.5504 1.9338 8.0046
K-562 GDSC2 3.619 6.5107 1.9679 7.7421
KCL-22 GDSC2 3.6644 6.8776 1.8208 8.5416
EM-2 GDSC2 3.73 6.3727 2.1219 6.4889
NOMO-1 GDSC2 3.7777 7.3095 1.6941 9.0306
WIL2 NS GDSC2 3.804 6.2158 2.2545 5.4787
ATN-1 GDSC2 3.8572 5.5591 2.6119 3.1571
ROS-50 GDSC2 3.9767 6.6344 2.1746 5.5654
DB GDSC2 4.0007 8.5314 1.259 11.0979
KM-H2 GDSC2 4.0266 6.1959 2.4213 3.9494
KMOE-2 GDSC2 4.0858 6.5138 2.309 4.5023
U266B1 GDSC2 4.0955 7.6347 1.7713 7.7636
L-428 GDSC2 4.326 14.2169 -1.3131 22.7673
HDLM-2 GDSC2 4.3526 6.6385 2.4237 3.2962
HH [Human lymphoma] GDSC2 4.3566 7.736 1.9063 6.3518
Granta-519 GDSC2 4.3725 7.6603 1.9535 6.0343
DG-75 GDSC2 4.4297 8.4301 1.6218 7.8966
RS4;11 GDSC2 4.5286 7.795 1.9934 5.474
TK [Human B-cell lymphoma] GDSC2 4.5383 6.4434 2.6204 1.9129
KG-1 GDSC2 4.6695 9.2264 1.4033 8.6552
SUP-B15 GDSC2 4.8295 8.2458 1.9742 5.007
Hs 445 GDSC2 4.9623 15.6893 -1.5536 22.0677
LC4-1 GDSC2 5.0923 7.0702 2.6371 1.1829
SK-MM-2 GDSC2 5.1337 7.3295 2.5508 1.5158
RC-K8 GDSC2 5.1566 6.6975 2.8107 0.4964
EJM GDSC2 5.2634 7.7256 2.4502 1.8309
LP-1 GDSC2 5.2731 7.0036 2.7436 0.6372
KOPN-8 GDSC2 5.3721 17.2385 -2.0104 22.6867
Karpas-231 GDSC2 5.3748 6.8604 2.8372 0.3182
SU-DHL-8 GDSC2 5.4591 7.7076 2.5511 1.1993
JJN-3 GDSC2 6.0041 7.5702 2.8197 0.1641
MOLT-4 GDSC2 6.3102 8.2028 2.7116 0.265
⏷ Show the Full List of 157 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC2 1.4154 8.1996 -0.8438 30.2981
FLO-1 GDSC2 2.2792 6.5127 0.7918 19.1456
OACM5.1 C GDSC2 2.4073 6.4665 0.9348 17.8641
OACP4 C GDSC2 3.1388 5.5603 2.0467 8.6211
TE-12 GDSC2 3.5016 7.0267 1.6171 10.2543
HCE-4 GDSC2 4.318 9.9999 0.7724 13.096
SK-GT-4 GDSC2 4.4256 12.6443 -0.4544 18.9891
KYAE-1 GDSC2 4.4641 9.4575 1.1461 10.6183
ESO-26 GDSC2 5.0259 13.44 -0.3968 17.2474
KYSE-50 GDSC2 5.5816 7.5002 2.6845 0.6351
ESO-51 GDSC2 6.1051 8.2026 2.6347 0.5054
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 1.7408 3.5785 1.5201 17.047
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC2 1.1365 5.8318 -0.0215 27.9637
NB(TU)1 GDSC2 2.0085 3.933 1.6852 14.9507
SJNB-14 GDSC2 2.2737 3.5093 2.1218 11.3329
CHP-212 GDSC2 2.3565 3.9701 2.0407 11.4415
KP-N-YS GDSC2 2.4929 4.317 2.0347 10.9315
MHH-NB-11 GDSC2 2.7915 4.8678 2.0722 9.6026
KP-N-RT-BM-1 GDSC2 2.8473 4.8945 2.112 9.162
LA-N-6 GDSC2 2.9338 6.1225 1.5864 12.152
TGW GDSC2 3.0221 4.3712 2.5304 5.9571
Kelly GDSC2 3.1669 9.5131 0.0962 19.9237
SK-N-MC-IXC GDSC2 3.181 4.4546 2.6342 4.7821
SJNB-13 GDSC2 3.1916 6.1014 1.8221 9.8737
KP-N-YN GDSC2 3.2033 6.8459 1.4601 12.0934
SiMa GDSC2 3.3023 7.7555 1.0888 14.0462
SK-N-DZ GDSC2 3.365 8.1568 0.9403 14.733
SJNB-17 GDSC2 3.3912 7.3119 1.3844 12.0032
SJNB-5 GDSC2 3.6198 5.6799 2.381 5.1453
SJNB-10 GDSC2 3.7842 6.8139 1.9446 7.4579
CHP-126 GDSC2 3.8963 5.76 2.542 3.4972
NH-12 GDSC2 3.9735 6.2524 2.3577 4.4502
GI-ME-N GDSC2 3.9913 6.7407 2.1332 5.7866
SJNB-6 GDSC2 4.0675 7.1451 1.9905 6.4872
CHP-134 GDSC2 4.1865 7.2738 2.0119 6.0861
SK-N-AS GDSC2 4.6246 14.0131 -0.9806 20.7172
SJNB-7 GDSC2 4.9012 6.8587 2.6317 1.4029
SK-N-BE(2)-M17 GDSC2 5.2327 8.7192 2.0003 4.1681
GOTO GDSC2 5.4605 7.5108 2.6291 0.9016
IMR-5 GDSC2 5.463 11.3319 0.9299 9.6474
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 3.7651 6.4595 2.1055 6.5031
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1569 GDSC2 1.9648 5.4793 0.9755 19.2646
DU4475 GDSC2 2.2108 3.1716 2.1468 11.4827
HCC1500 GDSC2 2.5027 6.6839 0.9174 17.6304
CAL-85-1 GDSC2 2.5663 5.0847 1.7523 12.3739
HCC1599 GDSC2 2.7852 4.5551 2.216 8.7361
Hs 578T GDSC2 2.9123 4.9889 2.1265 8.8501
MDA-MB-453 GDSC2 3.0674 5.6248 1.9521 9.44
YMB-1-E GDSC2 3.0987 4.437 2.569 5.4586
MDA-MB-468 GDSC2 3.2355 4.3803 2.7191 4.0757
MDA-MB-415 GDSC2 3.3679 8.4669 0.7876 15.603
HCC2157 GDSC2 3.5443 5.4321 2.4459 4.9326
HCC1806 GDSC2 3.6344 8.1135 1.1813 12.5399
CAL-120 GDSC2 3.6522 6.1305 2.1825 6.308
HCC1143 GDSC2 3.7217 8.0589 1.2778 11.7222
HDQ-P1 GDSC2 3.8328 6.7331 2.0211 6.86
Evsa-T GDSC2 3.9102 6.2832 2.2983 4.9571
COLO 824 GDSC2 4.1149 8.8776 1.1741 11.3089
CAL-51 GDSC2 4.2056 7.4924 1.9194 6.6059
MDA-MB-231 GDSC2 4.2158 6.5339 2.3858 3.776
HCC38 GDSC2 4.2825 7.0982 2.1619 4.974
UACC-893 GDSC2 4.407 11.3132 0.1906 15.9624
JIMT-1 GDSC2 4.4899 6.0601 2.7601 1.278
MDA-MB-361 GDSC2 4.5217 7.12 2.3052 3.6703
HCC1419 GDSC2 4.5252 10.6056 0.6278 13.3761
HCC1937 GDSC2 4.6512 8.7159 1.6362 7.3297
BT-549 GDSC2 4.6869 8.0098 1.9945 5.1578
MDA-MB-157 GDSC2 4.7639 7.0457 2.48 2.3208
T-47D GDSC2 4.8022 11.4112 0.4348 13.7354
MRK-nu-1 GDSC2 4.8346 6.427 2.776 0.8504
AU565 GDSC2 4.9094 8.2319 2.0299 4.5466
BT-474 GDSC2 5.0108 6.7485 2.7284 0.8864
OCUB-M GDSC2 5.145 9.4883 1.5933 6.5901
HCC2218 GDSC2 5.308 8.4695 2.1542 3.2355
HCC1428 GDSC2 5.3544 6.6082 2.9183 0.1603
EFM-19 GDSC2 5.424 7.6287 2.5665 1.1687
MCF-7 GDSC2 5.4967 12.5054 0.3919 12.3963
CAMA-1 GDSC2 5.4976 7.3757 2.6966 0.6477
MFM-223 GDSC2 5.5991 14.96 -0.7258 17.3676
HCC1954 GDSC2 5.6713 7.6976 2.6473 0.6973
HCC1187 GDSC2 5.7089 7.2954 2.8083 0.2609
HCC70 GDSC2 5.7472 7.4911 2.7533 0.3665
BT-20 GDSC2 5.8066 7.3109 2.8383 0.18
EFM-192A GDSC2 5.8193 7.7063 2.7035 0.458
MDA-MB-330 GDSC2 5.9386 13.3329 0.2933 11.9754
ZR-75-30 GDSC2 5.9928 15.4138 -0.6688 16.2756
MDA-MB-436 GDSC2 6.2915 7.9139 2.8035 0.1316
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SF539 GDSC2 2.0089 4.5579 1.4316 16.423
D283 Med GDSC2 2.05 3.5795 1.8558 13.8058
D-423MG GDSC2 2.1617 4.5653 1.5861 14.9032
D-336MG GDSC2 2.5034 7.6384 0.4486 20.2572
PFSK-1 GDSC2 3.0037 7.0402 1.1913 14.3481
Hs 683 GDSC2 3.0386 7.5303 0.9772 15.5112
KS-1 [Human Krukenberg tumour] GDSC2 3.0771 6.2553 1.6466 11.3238
42-MG-BA GDSC2 3.0802 5.5114 2.0198 8.9735
D-247MG GDSC2 3.2987 5.3308 2.298 6.5505
SF126 GDSC2 3.3007 4.9511 2.4895 5.3324
D-566MG GDSC2 3.404 5.424 2.3385 5.9918
AM-38 GDSC2 3.4438 7.3053 1.4309 11.567
D-502MG GDSC2 3.4759 6.8356 1.6917 9.8619
SNB-75 GDSC2 3.4794 5.0946 2.5631 4.3657
8-MG-BA GDSC2 3.6825 9.84 0.3583 17.0445
GI-1 GDSC2 3.7111 6.1118 2.2366 5.8191
SK-MG-1 GDSC2 3.7557 6.6797 1.9894 7.2512
D-245MG GDSC2 3.7616 6.47 2.0976 6.5614
D-542MG GDSC2 3.8658 9.6574 0.5952 15.2601
D-392MG GDSC2 3.8686 9.2473 0.8016 14.104
Becker GDSC2 3.8909 6.5936 2.1326 6.0262
LN-229 GDSC2 3.893 10.2836 0.3048 16.7367
M059J GDSC2 4.0119 6.365 2.3299 4.5352
T98G GDSC2 4.1283 6.6125 2.2905 4.5242
H4 GDSC2 4.1338 16.1197 -2.4136 26.9128
KNS-42 GDSC2 4.171 6.739 2.2587 4.6256
YKG-1 GDSC2 4.1817 6.8794 2.1987 4.9644
SF295 GDSC2 4.1934 5.8234 2.7011 2.0042
DBTRG-05MG GDSC2 4.2227 6.4513 2.4291 3.5074
DK-MG GDSC2 4.2638 6.5127 2.4265 3.4442
KINGS-1 GDSC2 4.2688 10.9309 0.2749 15.8875
GaMG GDSC2 4.4531 8.1729 1.7622 7.0068
KNS-81-FD GDSC2 4.4556 7.4622 2.1032 4.9713
CAS-1 GDSC2 4.4698 6.6983 2.4673 2.8446
SW1088 GDSC2 4.4704 7.4565 2.1155 4.8697
LN-18 GDSC2 4.5677 6.2647 2.7132 1.4083
KALS-1 GDSC2 4.5934 8.0993 1.8916 5.9441
Onda 10 GDSC2 4.6228 6.7771 2.5202 2.3154
LN-405 GDSC2 4.6628 6.3086 2.7427 1.1603
SF268 GDSC2 4.6702 9.3419 1.348 8.9752
YH-13 GDSC2 4.6736 9.9145 1.0729 10.55
U-118MG GDSC2 4.7354 10.2077 0.9741 10.9669
GB-1 GDSC2 4.7843 9.2175 1.4858 7.928
ONS-76 GDSC2 4.8192 11.4666 0.42 13.7719
U-251MG GDSC2 4.8419 10.3825 0.9641 10.7811
Daoy GDSC2 4.9491 16.5541 -1.9918 23.6028
U-87MG ATCC GDSC2 4.991 10.1354 1.1858 9.2105
NMC-G1 GDSC2 5.0283 7.0597 2.6108 1.3604
A-172 GDSC2 5.188 7.3908 2.552 1.4536
D-263MG GDSC2 5.4932 9.8921 1.6216 5.8041
Onda 11 GDSC2 6.1819 8.3448 2.6131 0.5262
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC2 4.2787 9.746 0.8682 12.658
TGBC24TKB GDSC2 5.2145 7.1486 2.662 0.9732
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC2 3.3515 7.0916 1.4617 11.6443
KLE GDSC2 3.9283 8.3175 1.3098 10.9818
MFE-280 GDSC2 4.003 7.623 1.7092 8.3675
RL95-2 GDSC2 4.3496 9.3627 1.1093 11.105
AN3-CA GDSC2 4.5536 9.7912 1.0474 10.9734
EN GDSC2 4.7151 12.972 -0.397 18.0005
MFE-319 GDSC2 5.6005 6.9626 2.8844 0.1556
MFE-296 GDSC2 6.3797 8.2081 2.7346 0.2092
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB65-RCC GDSC2 1.1404 3.1216 0.9927 22.6613
CAL-54 GDSC2 1.8916 7.0874 0.1458 24.0608
Caki-1 GDSC2 2.1625 5.355 1.2295 17.0216
KTCTL-13 GDSC2 2.2903 4.6795 1.6667 13.9215
KTCTL-140 GDSC2 2.304 4.2534 1.8678 12.67
UO-31 GDSC2 2.3561 4.1327 1.9732 11.8386
KTCTL-1M GDSC2 2.5996 5.1754 1.741 12.3237
KTCTL-26A GDSC2 2.8983 4.2563 2.4675 6.7815
LB2241-RCC GDSC2 3.0945 4.6656 2.4522 6.2054
ACHN GDSC2 3.174 7.6802 1.0184 14.8498
LB996-RCC GDSC2 3.2731 6.0814 1.9013 9.132
HA7-RCC GDSC2 3.3034 5.4453 2.2447 6.8739
BFTC-909 GDSC2 3.359 5.8888 2.0693 7.8216
KTCTL-195 GDSC2 3.3938 7.1387 1.4731 11.4511
A-704 GDSC2 3.4594 5.5238 2.3334 5.8701
SW13 GDSC2 3.5487 5.4575 2.4367 4.9793
NCC021 GDSC2 3.6652 6.8878 1.8164 8.5667
KTCTL-21 GDSC2 3.7126 6.8452 1.8743 8.0807
RCC10RGB GDSC2 3.7888 6.647 2.0306 6.9106
A-498 GDSC2 3.8135 9.6281 0.5686 15.5494
TK-10 GDSC2 3.8186 9.0002 0.8854 13.7635
LB1047-RCC GDSC2 4.0212 8.1588 1.4586 9.8486
NCC010 GDSC2 4.2448 7.6916 1.8503 6.937
SW156 GDSC2 4.3089 6.4351 2.4908 2.9903
RXF 393L GDSC2 4.3342 12.9816 -0.6924 20.2661
OS-RC-2 GDSC2 4.3536 13.6769 -1.0229 21.5767
KMRC-20 GDSC2 4.3611 8.2372 1.6672 7.7788
769-P GDSC2 4.6148 14.4463 -1.2029 21.6152
786-O GDSC2 4.6191 9.979 1.0027 11.074
VMRC-RCW GDSC2 5.0338 6.7286 2.7465 0.7985
VMRC-RCZ GDSC2 5.7729 7.828 2.6402 0.6593
SN12C GDSC2 5.8814 17.2262 -1.6297 20.2579
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KM12 GDSC2 0.9995 3.922 0.6015 25.409
HCC2998 GDSC2 1.8981 3.7159 1.6451 15.6541
HCT 15 GDSC2 2.3249 4.7902 1.6515 13.8802
HT-29 GDSC2 2.4486 3.8326 2.1933 10.1738
HT-55 GDSC2 2.7323 4.3913 2.2413 8.7743
SNU-C5 GDSC2 3.0143 7.644 0.8994 16.0414
LS513 GDSC2 3.0607 5.2098 2.1524 8.2006
NCI-H747 GDSC2 3.1805 5.29 2.2177 7.4133
HCT 116 GDSC2 3.2016 4.6945 2.5329 5.3566
SNU-175 GDSC2 3.2573 5.5824 2.1374 7.6888
SW48 GDSC2 3.303 8.0295 0.9524 14.847
SNU-283 GDSC2 3.4126 4.7917 2.6612 3.9272
GP5d GDSC2 3.4279 7.4056 1.3677 11.9986
COLO205 GDSC2 3.4345 5.5442 2.3031 6.1302
NCI-H508 GDSC2 3.4874 4.8917 2.6703 3.6692
SNU-81 GDSC2 3.508 5.6117 2.3282 5.7713
LS411N GDSC2 3.5081 7.0692 1.6011 10.3351
RCM-1 [Human ESC] GDSC2 3.5387 5.2874 2.5135 4.5221
SNU-C1 GDSC2 3.5551 6.3547 1.9952 7.7419
CCK-81 GDSC2 3.6802 5.6211 2.4555 4.5278
SW620 GDSC2 3.7119 6.5505 2.02 7.1722
HT115 GDSC2 3.7714 7.617 1.5365 10.0178
CL-11 GDSC2 3.7908 6.7044 2.0038 7.0725
MDST8 GDSC2 3.9853 5.7469 2.6077 2.9182
LoVo GDSC2 4.0802 7.3835 1.8832 7.1155
SNU-61 GDSC2 4.1092 11.4779 -0.12 18.2721
NCI-H716 GDSC2 4.1244 6.6577 2.2662 4.679
RKO GDSC2 4.4011 7.1895 2.1966 4.5282
SW626 GDSC2 4.4442 8.1319 1.7758 6.9446
SW1116 GDSC2 4.6248 6.9007 2.4663 2.6005
SNU-C2B GDSC2 4.6328 12.7197 -0.3342 17.9194
SW1463 GDSC2 4.6801 11.673 0.2172 15.1468
C2BBe1 GDSC2 4.6862 13.2223 -0.5424 18.7201
LS123 GDSC2 4.7676 6.6235 2.6634 1.4073
LS180 GDSC2 4.8161 6.7317 2.6424 1.4495
SNU-407 GDSC2 4.8936 10.3757 1.0034 10.4464
COLO 678 GDSC2 4.9516 7.6844 2.3024 2.9797
CaR-1 GDSC2 5.005 9.8637 1.325 8.3915
SNU-1040 GDSC2 5.0497 6.3855 2.8831 0.3458
SW948 GDSC2 5.0608 6.4701 2.8564 0.4142
DiFi GDSC2 5.0851 7.7155 2.3622 2.4793
SW1417 GDSC2 5.147 7.2484 2.5906 1.3276
SW837 GDSC2 5.1623 15.7804 -1.448 21.2125
T84 GDSC2 5.2064 7.5199 2.5076 1.6317
COLO 320HSR GDSC2 5.4254 7.6134 2.5732 1.141
LS1034 GDSC2 5.4762 6.8323 2.8848 0.186
SK-CO-1 GDSC2 5.8085 7.4635 2.7861 0.2734
CW-2 GDSC2 6.1822 8.4189 2.5861 0.5974
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 5.4189 7.0423 2.7885 0.4218
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-387 GDSC2 1.9588 3.5409 1.7693 14.6923
Hep 3B2.1-7 GDSC2 2.8827 5.2068 1.9924 9.7871
SNU-423 GDSC2 2.8916 8.5962 0.3181 19.6542
JHH-6 GDSC2 3.0157 8.4007 0.523 18.1585
JHH-4 GDSC2 3.0618 8.7243 0.401 18.6721
SNU-449 GDSC2 3.354 8.1402 0.9394 14.7708
JHH-2 GDSC2 3.396 6.2866 1.9008 8.7783
SNU-398 GDSC2 3.5136 7.0003 1.6399 10.0789
SK-HEP-1 GDSC2 3.8243 5.7112 2.5156 3.8164
Hep-G2/C3A GDSC2 4.1105 6.8461 2.1659 5.3176
HLE GDSC2 4.1408 9.6832 0.7953 13.4193
HuH-1 GDSC2 4.1412 8.7175 1.2727 10.6611
Huh-7 GDSC2 4.1955 6.6117 2.3357 4.1142
JHH-1 GDSC2 4.4958 6.0669 2.7602 1.2702
JHH-7 GDSC2 5.894 8.7489 2.3345 1.6861
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 166 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1755 GDSC2 1.3856 6.0465 0.1355 26.1365
COR-L303 GDSC2 1.4161 3.9508 1.0418 21.1445
NCI-H2171 GDSC2 1.5419 3.1122 1.4323 18.4335
NCI-H292 GDSC2 1.5511 4.631 0.9229 21.2319
NCI-H82 GDSC2 1.8463 3.0593 1.7749 15.1782
LCLC-103H GDSC2 1.8529 9.5366 -1.0809 29.5012
NCI-H1975 GDSC2 1.8699 3.7892 1.5889 16.0938
NCI-H2795 GDSC2 2.0589 6.8377 0.4256 21.9776
NCI-H250 GDSC2 2.08 8.514 -0.37 25.7981
NCI-H1792 GDSC2 2.0865 3.8354 1.8054 13.9319
Lu-134-A GDSC2 2.1169 4.8142 1.4303 16.0035
BEN GDSC2 2.147 4.2727 1.696 14.3136
NCI-H3122 GDSC2 2.1679 3.9185 1.861 13.2681
IST-SL1 GDSC2 2.2075 3.4942 2.0547 11.9998
SBC-1 GDSC2 2.2367 3.9387 1.9264 12.6025
NCI-H838 GDSC2 2.2809 4.8574 1.5767 14.4972
COR-L32 GDSC2 2.2934 4.046 1.9434 12.2687
NCI-H2110 GDSC2 2.2957 3.892 2.0074 11.8877
A-549 GDSC2 2.327 7.9566 0.1309 22.5313
NCI-H2122 GDSC2 2.3278 4.1174 1.95 12.0893
LC-2/ad GDSC2 2.3419 4.4694 1.8129 12.8459
NCI-H146 GDSC2 2.3692 3.6682 2.1707 10.6399
CPC-N GDSC2 2.3995 3.6843 2.1974 10.358
NCI-H209 GDSC2 2.443 9.8188 -0.6852 25.8704
NCI-H460 GDSC2 2.4773 3.9329 2.1832 10.1142
EMC-BAC-1 GDSC2 2.4898 4.9484 1.7422 12.7137
CAL-12T GDSC2 2.5108 5.0423 1.7184 12.7818
PC-14 GDSC2 2.5287 4.8688 1.8176 12.1106
COR-L321 GDSC2 2.5716 3.6701 2.3872 8.5397
NCI-H211 GDSC2 2.5757 3.7341 2.367 8.6389
NCI-H647 GDSC2 2.6295 3.9161 2.3495 8.5199
LXF 289 GDSC2 2.6753 6.3614 1.2346 15.1595
NCI-H2085 GDSC2 2.6907 8.091 0.3929 19.9188
LB647-SCLC GDSC2 2.7103 4.295 2.2641 8.7174
RERF-LC-MS GDSC2 2.7385 4.8957 2.0082 10.1847
HCC33 GDSC2 2.761 3.6435 2.5995 6.52
NCI-H2810 GDSC2 2.7637 5.3384 1.8176 11.2785
HCC78 GDSC2 2.7895 7.7799 0.635 18.2704
LOU-NH91 GDSC2 2.7937 6.4708 1.2882 14.4394
NCI-H524 GDSC2 2.8071 4.7811 2.1287 9.1977
NCI-H2227 GDSC2 2.8291 3.9556 2.5378 6.6121
SHP-77 GDSC2 2.8694 5.1717 1.9973 9.8015
Ms-1 GDSC2 2.8851 5.3571 1.9208 10.2264
Lu-65 GDSC2 2.8867 4.4768 2.3512 7.5407
NCI-H2023 GDSC2 2.9056 4.7795 2.2226 8.2731
NCI-H1734 GDSC2 2.9139 4.3935 2.4172 7.0366
SW1271 GDSC2 2.917 5.215 2.0199 9.5006
NCI-H748 GDSC2 2.9386 5.8757 1.7131 11.3481
COLO 668 GDSC2 2.9636 5.6306 1.8569 10.3688
NCI-H2081 GDSC2 3.026 12.4495 -1.4907 27.0481
NCI-H358 GDSC2 3.0452 5.9705 1.7605 10.7121
EMC-BAC-2 GDSC2 3.0509 5.41 2.0442 8.9128
NCI-H2804 GDSC2 3.06 5.3362 2.089 8.6021
NCI-H1915 GDSC2 3.0802 4.9943 2.2766 7.3563
LCLC-97TM1 GDSC2 3.0843 7.4299 1.0667 14.8408
EPLC-272H GDSC2 3.0881 6.0317 1.7675 10.5339
NCI-H290 GDSC2 3.101 4.1793 2.6976 4.6458
HCC44 GDSC2 3.1075 4.7542 2.42 6.366
NCI-H322M GDSC2 3.1283 14.2574 -2.308 29.3183
NCI-H1437 GDSC2 3.1332 4.6947 2.4725 5.9532
COR-L311 GDSC2 3.1421 4.8132 2.4216 6.2456
NCI-H2030 GDSC2 3.1459 6.1187 1.7742 10.3135
NCI-H1666 GDSC2 3.1501 7.9332 0.8716 15.7797
NCI-H2869 GDSC2 3.1804 7.3257 1.2009 13.7429
NCI-H2291 GDSC2 3.2267 5.6373 2.0839 8.1185
SBC-3 GDSC2 3.2648 4.777 2.5463 5.0798
NCI-H345 GDSC2 3.3072 10.3697 -0.2143 21.0048
HCC366 GDSC2 3.3721 6.7685 1.6403 10.4786
NCI-H596 GDSC2 3.3722 5.2134 2.4177 5.5807
HARA [Human squamous cell lung carcinoma] GDSC2 3.4082 6.02 2.0441 7.8409
RERF-LC-KJ GDSC2 3.4152 5.6121 2.2537 6.4968
NCI-H1299 GDSC2 3.4199 7.016 1.5559 10.8646
DMS 273 GDSC2 3.4592 6.0283 2.0813 7.4627
NCI-H441 GDSC2 3.4829 9.6297 0.3012 17.9207
NCI-H1869 GDSC2 3.5055 7.5076 1.38 11.7023
NCI-H2228 GDSC2 3.5119 9.0568 0.6112 16.1696
NCI-H2196 GDSC2 3.5544 5.4241 2.4577 4.8319
NCI-H2461 GDSC2 3.5763 6.7954 1.7923 8.9564
Calu-3 GDSC2 3.5799 6.4514 1.9666 7.8545
NCI-H1944 GDSC2 3.5953 6.7093 1.8504 8.5418
Lu-139 GDSC2 3.6065 7.5812 1.4246 11.1483
NCI-H2373 GDSC2 3.6228 8.1082 1.1747 12.6117
NCI-H650 GDSC2 3.6262 6.7161 1.8712 8.3282
SBC-5 GDSC2 3.6337 5.9537 2.256 5.8942
COR-L105 GDSC2 3.6634 10.9512 -0.212 19.9455
NCI-H1651 GDSC2 3.6801 14.0175 -1.7304 25.9738
NCI-H1781 GDSC2 3.7062 5.994 2.2911 5.4908
NCI-H2170 GDSC2 3.7329 8.0864 1.2729 11.7213
DMS 79 GDSC2 3.7337 6.6247 1.9999 7.2422
HOP-62 GDSC2 3.7353 5.794 2.4112 4.67
NCI-H2731 GDSC2 3.7515 7.061 1.7972 8.4593
Lu-135 GDSC2 3.7619 6.5149 2.0757 6.6972
SK-MES-1 GDSC2 3.7646 6.6568 2.0075 7.1157
NCI-H3255 GDSC2 3.7922 6.4877 2.1118 6.3957
VMRC-LCD GDSC2 3.7949 10.1477 0.2948 17.0606
NCI-H1581 GDSC2 3.8016 7.1103 1.8112 8.2435
NCI-H1836 GDSC2 3.8063 6.8413 1.9478 7.3821
IST-SL2 GDSC2 3.8317 7.5301 1.6261 9.3095
NCI-H226 GDSC2 3.849 10.966 -0.0702 18.7436
NCI-H522 GDSC2 3.9137 8.8255 1.0464 12.5773
Lu-99A GDSC2 3.9268 7.1918 1.865 7.5958
NCI-H727 GDSC2 3.9272 11.5704 -0.3094 19.6579
COR-L23 GDSC2 3.9522 8.18 1.3961 10.4011
A-427 GDSC2 3.976 10.0462 0.4881 15.5415
NCI-H2029 GDSC2 4.026 8.1837 1.45 9.8885
UMC-11 GDSC2 4.0301 8.1126 1.4881 9.6481
HCC15 GDSC2 4.0349 9.6587 0.7263 14.0813
NCI-H1568 GDSC2 4.0423 16.2876 -2.5708 27.5973
NCI-H2803 GDSC2 4.0455 6.8946 2.0968 5.8855
HCC827 GDSC2 4.1251 11.2943 -0.0163 17.7279
NCI-H520 GDSC2 4.1565 11.8636 -0.2749 18.8763
NCI-H810 GDSC2 4.1628 7.1051 2.077 5.7428
NCI-H2141 GDSC2 4.1859 6.2091 2.5192 3.0514
NCI-H1993 GDSC2 4.2021 7.6078 1.8608 6.9699
NCI-H2818 GDSC2 4.2532 11.1034 0.1774 16.4255
NCI-H1694 GDSC2 4.2553 6.4914 2.4311 3.4337
NCI-H720 GDSC2 4.2607 6.3665 2.4927 3.0662
NCI-H1876 GDSC2 4.323 7.1234 2.1768 4.8019
NCI-H2444 GDSC2 4.3496 6.0225 2.7014 1.7614
HOP-92 GDSC2 4.3935 8.6772 1.4763 8.8461
SK-LU-1 GDSC2 4.4089 9.4711 1.0995 11.0188
NCI-H1693 GDSC2 4.4139 6.8595 2.3592 3.5557
NCI-H2087 GDSC2 4.4566 8.2059 1.7486 7.08
NCI-H2722 GDSC2 4.4858 7.1472 2.2703 3.9364
NCI-H1155 GDSC2 4.4999 6.2542 2.6821 1.6501
EBC-1 GDSC2 4.5121 7.9556 1.9062 6.0241
Lu-165 GDSC2 4.5487 8.7644 1.5428 8.1017
KNS-62 GDSC2 4.5532 11.0006 0.4541 14.2348
RERF-LC-Sq1 GDSC2 4.5632 8.9904 1.4437 8.6538
NCI-H1436 GDSC2 4.5958 6.1402 2.7796 1.0666
NCI-H740 GDSC2 4.631 7.3863 2.2494 3.7941
NCI-H1770 GDSC2 4.6793 8.7599 1.634 7.2833
NCI-H1793 GDSC2 4.693 11.731 0.1981 15.2113
NCI-H1623 GDSC2 4.7093 6.9324 2.4997 2.2963
NCI-H1092 GDSC2 4.725 7.1091 2.4303 2.6403
NCI-H1563 GDSC2 4.7507 8.049 2.0165 4.91
NCI-H2369 GDSC2 4.7565 7.9015 2.0886 4.4861
NCI-H513 GDSC2 4.8517 11.9743 0.195 14.8447
DMS 114 GDSC2 4.8827 8.6634 1.8129 5.8343
NCI-H1105 GDSC2 4.9219 6.8142 2.6603 1.2529
NCI-H1048 GDSC2 4.9658 6.7001 2.7272 0.9299
NCI-H1355 GDSC2 5.0473 12.6148 0.0232 15.2315
EKVX GDSC2 5.0711 8.5994 1.9592 4.6626
IA-LM GDSC2 5.0736 7.0578 2.6333 1.2169
ChaGo-K-1 GDSC2 5.1042 8.745 1.9125 4.8661
NCI-H2172 GDSC2 5.1086 6.9308 2.7003 0.9133
NCI-H510A GDSC2 5.2167 6.8297 2.7858 0.5374
NCI-H1963 GDSC2 5.2461 7.1952 2.6578 0.9632
NCI-H23 GDSC2 5.2862 13.2912 -0.1357 15.4406
DMS 53 GDSC2 5.3964 7.5752 2.5752 1.1581
NCI-H2405 GDSC2 5.4756 10.5124 1.3238 7.4726
LK-2 GDSC2 5.5007 14.7832 -0.71 17.5198
NCI-H841 GDSC2 5.5028 7.3976 2.6905 0.664
NCI-H196 GDSC2 5.5052 9.8195 1.6619 5.5629
NCI-H526 GDSC2 5.6054 16.029 -1.2436 19.4355
NCI-H2591 GDSC2 5.6109 14.4301 -0.4595 16.1914
ABC-1 GDSC2 5.6215 15.3291 -0.8898 17.9991
NCI-H1435 GDSC2 5.6462 7.3367 2.7701 0.3675
NCI-H2135 GDSC2 5.737 7.097 2.8867 0.1242
SW1573 GDSC2 5.7863 8.9143 2.2144 2.327
NCI-H446 GDSC2 5.8187 7.6065 2.7392 0.371
LC-1/sq GDSC2 6.0287 14.0497 0.0116 13.1514
NCI-H661 GDSC2 6.2657 8.1477 2.7146 0.2721
NCI-H2595 GDSC2 6.3043 8.611 2.564 0.5978
Calu-6 GDSC2 6.5281 17.2154 -1.1684 17.1993
NCI-H1650 GDSC2 6.7411 20.912 -2.8121 22.2997
⏷ Show the Full List of 166 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 2.5966 7.6432 0.5306 19.4929
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-11 GDSC2 2.0271 4.0684 1.6527 15.0596
OE33 GDSC2 2.8476 6.9895 1.0793 15.5186
KYSE-510 GDSC2 2.9891 9.8381 -0.2175 22.005
EC-GI-10 GDSC2 3.2398 7.6945 1.0668 14.3639
KYSE-140 GDSC2 3.4517 5.9655 2.1067 7.3237
OE19 GDSC2 3.4827 4.7985 2.7129 3.413
KYSE-410 GDSC2 3.495 9.6242 0.3138 17.8189
TE-10 GDSC2 3.5656 5.9908 2.1847 6.5212
TE-9 GDSC2 3.8765 5.2632 2.7654 2.1999
COLO 680N GDSC2 3.967 7.6754 1.6567 8.7787
TE-15 GDSC2 4.0595 7.89 1.6196 8.7765
TE-6 GDSC2 4.3274 10.7998 0.3844 15.168
TE-8 GDSC2 4.4182 11.8711 -0.077 17.2549
TE-4 GDSC2 4.522 8.5036 1.6502 7.5242
KYSE-270 GDSC2 4.5295 11.1221 0.3768 14.6984
OE21 GDSC2 4.9583 9.7803 1.3336 8.4396
TE-1 GDSC2 5.2501 10.7913 1.0462 9.4473
KYSE-180 GDSC2 5.2774 19.0938 -2.9995 25.8561
KYSE-70 GDSC2 5.2925 12.2649 0.3671 12.9642
TE-5 GDSC2 5.3771 12.2757 0.4204 12.5079
KYSE-520 GDSC2 5.7175 18.853 -2.5488 23.6144
KYSE-450 GDSC2 6.1744 17.5421 -1.5739 19.4371
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVCAR-5 GDSC2 2.0886 4.7406 1.4341 16.0919
A2780 GDSC2 2.4855 5.4799 1.4857 14.2933
OVTOKO GDSC2 2.6315 8.6997 0.038 21.9424
IGROV-1 GDSC2 2.6708 4.3315 2.2078 9.2075
JHOS-4 GDSC2 2.801 4.0397 2.4716 7.1187
DOV13 GDSC2 2.9175 3.8812 2.6608 5.532
EFO-27 GDSC2 3.1806 7.0569 1.3354 12.9275
JHOS-2 GDSC2 3.2634 5.3674 2.25 6.959
TOV-21G GDSC2 3.2903 7.3646 1.2742 12.9702
TYK-nu GDSC2 3.4706 5.0629 2.5721 4.3328
OVISE GDSC2 3.5803 6.3599 2.0126 7.5648
ES-2 GDSC2 3.8478 6.2535 2.268 5.2902
EFO-21 GDSC2 3.8714 7.7704 1.5374 9.7514
TOV-112D GDSC2 4.072 7.0549 2.0376 6.1876
OV56 GDSC2 4.1101 8.5161 1.3488 10.2858
Caov-3 GDSC2 4.2276 6.253 2.5248 2.9417
OVCAR-8 GDSC2 4.2538 9.589 0.927 12.3876
SK-OV-3 GDSC2 4.5207 10.1268 0.8595 12.1123
OVCAR-4 GDSC2 4.8776 9.8618 1.2401 9.1443
OVCAR-3 GDSC2 5.2858 7.0808 2.7196 0.7092
OVK18 GDSC2 5.6085 7.2008 2.8043 0.3036
OAW28 GDSC2 5.7348 10.9928 1.2623 7.3333
OAW42 GDSC2 6.0206 16.7858 -1.315 18.8053
OV-90 GDSC2 6.7347 15.1629 -0.0534 12.0878
Kuramochi GDSC2 7.0937 17.8017 -1.0673 15.7124
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Panc 02.03 GDSC2 2.6773 8.6565 0.1 21.4796
HPAC GDSC2 2.7559 6.4378 1.2703 14.6734
MIA PaCa-2 GDSC2 3.3366 5.0927 2.4487 5.4862
QGP-1 GDSC2 3.3737 8.8261 0.6128 16.5668
PSN1 GDSC2 3.4315 5.1353 2.5049 4.8634
DAN-G GDSC2 3.6934 7.5515 1.5082 10.3996
PL4 GDSC2 3.7252 6.0292 2.2879 5.4632
Panc 10.05 GDSC2 3.7451 7.6535 1.4979 10.3237
Capan-1 GDSC2 3.9122 5.7468 2.5591 3.3593
MZ-PC-1 GDSC2 3.9403 6.279 2.3217 4.7447
HPAF-II GDSC2 3.9765 10.8985 0.0644 17.731
HuP-T3 GDSC2 3.9913 9.5747 0.7344 14.1518
Capan-2 GDSC2 4.0811 13.3168 -1.0578 22.4329
CFPAC-1 GDSC2 4.1741 9.9521 0.6875 13.9326
Panc 08.13 GDSC2 4.1993 9.1457 1.105 11.5007
KP-3 GDSC2 4.354 8.198 1.6812 7.711
BxPC-3 GDSC2 4.4102 9.3757 1.1471 10.7402
AsPC-1 GDSC2 4.5439 9.5329 1.1665 10.3132
PaTu 8902 GDSC2 4.5611 9.2868 1.2984 9.5088
SUIT-2 GDSC2 4.5906 8.5241 1.6871 7.1577
KP-4 GDSC2 4.732 6.5837 2.6622 1.4542
SU.86.86 GDSC2 4.9311 6.4823 2.7973 0.6904
KP-2 GDSC2 4.9805 16.8355 -2.1073 23.9036
PaTu 8988t GDSC2 5.0143 14.8537 -1.1015 20.2452
KP-1N GDSC2 5.3619 7.9576 2.4024 1.9402
HuP-T4 GDSC2 5.6547 12.2027 0.6428 10.7799
YAPC GDSC2 7.3325 18.3597 -1.1747 15.686
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC2 2.7912 7.2318 0.9088 16.7056
NCI-H28 GDSC2 3.0238 5.4553 1.9976 9.2922
MPP 89 GDSC2 3.896 9.3429 0.7755 14.1775
NCI-H2052 GDSC2 4.6406 9.9869 1.0143 10.9586
IST-Mes1 GDSC2 4.926 12.2083 0.1343 14.9711
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 GDSC2 2.3002 4.8201 1.6131 14.205
VCaP GDSC2 2.414 7.4767 0.4466 20.579
PC-3 GDSC2 3.6449 10.0079 0.2441 17.7476
LNCaP clone FGC GDSC2 3.7867 10.5669 0.0791 18.1834
NCI-H660 GDSC2 5.28 7.0741 2.7197 0.7128
DU145 GDSC2 6.3688 8.0576 2.7819 0.1451
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 4.223 6.3103 2.4953 3.1205
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MZ-MEL-2 GDSC2 1.3312 3.8205 0.9954 21.7764
LOX-IMVI GDSC2 1.4202 5.7121 0.3209 25.0522
CP50-MEL-B GDSC2 2.0262 3.336 1.904 13.6477
COLO 783 GDSC2 2.1414 3.6224 1.9406 12.9294
G-mel GDSC2 2.1601 3.2652 2.069 12.1368
IPC-298 GDSC2 2.2012 4.5351 1.6399 14.4286
A-431 GDSC2 2.2532 4.3052 1.793 13.3152
GAK GDSC2 2.2775 3.4172 2.1547 11.1338
RPMI-7951 GDSC2 2.282 7.3822 0.3712 21.4503
MZ-MEL-7 GDSC2 2.38 3.7371 2.1568 10.6732
SK-MEL-3 GDSC2 2.433 3.2481 2.371 9.2445
Mel Ho GDSC2 2.4478 3.4389 2.3336 9.381
Hs 938.T GDSC2 2.5369 4.1502 2.1531 10.052
COLO 792 GDSC2 2.5667 6.3325 1.1487 16.0455
IGR-37 GDSC2 2.5702 4.0705 2.222 9.5115
Hs 940.T GDSC2 2.6087 5.4272 1.6286 12.9826
SK-MEL-24 GDSC2 2.6593 5.8489 1.4712 13.7742
HT-144 GDSC2 2.6755 8.5452 0.1538 21.2138
SK-MEL-28 GDSC2 2.6839 3.5458 2.5538 7.109
G-361 GDSC2 2.7733 4.8666 2.0554 9.7701
WM1552C GDSC2 2.7854 5.0723 1.9674 10.2735
SK-MEL-30 GDSC2 2.8333 3.9211 2.5575 6.4776
WM35 GDSC2 2.8771 7.9739 0.6156 18.0929
A-375 GDSC2 2.8959 4.802 2.2025 8.4316
IGR-1 GDSC2 2.8984 4.005 2.5852 6.0623
M14 GDSC2 2.908 4.1335 2.5348 6.3338
VMRC-MELG GDSC2 2.9802 4.0755 2.6328 5.4705
WM278 GDSC2 2.9888 4.9989 2.1919 8.1862
SH-4 GDSC2 3.0468 4.583 2.4496 6.3789
HMV-II GDSC2 3.1088 6.1823 1.7105 10.8264
LB2518-MEL GDSC2 3.255 4.8611 2.4959 5.4276
MMAc-SF GDSC2 3.2617 4.5138 2.6751 4.274
SK-MEL-31 GDSC2 3.2683 10.3715 -0.2477 21.2791
COLO 829 GDSC2 3.2859 6.9267 1.4894 11.6659
A-388 GDSC2 3.4583 6.5739 1.8082 9.1835
Mel JuSo GDSC2 3.4597 5.129 2.5305 4.6246
451Lu GDSC2 3.5406 5.2334 2.5417 4.3395
SK-MEL-5 GDSC2 3.6268 6.7086 1.8754 8.3004
A2058 GDSC2 3.6288 11.8361 -0.6822 22.1507
DJM-1 GDSC2 3.6323 5.6834 2.3888 5.0645
A101D GDSC2 3.6483 11.0055 -0.2514 20.1738
UACC-62 GDSC2 3.6977 5.8195 2.3708 5.0136
WT2-iPS GDSC2 3.7035 6.4933 2.0419 7.0567
RVH-421 GDSC2 3.9211 6.615 2.1442 5.8829
UACC-257 GDSC2 3.9843 6.037 2.4689 3.7516
COLO 800 GDSC2 4.0827 6.9691 2.0869 5.8616
WM793 GDSC2 4.3211 6.1327 2.636 2.156
CP66-MEL GDSC2 4.5536 6.447 2.6271 1.8566
COLO 679 GDSC2 4.6621 12.6396 -0.2726 17.5629
SK-MEL-2 GDSC2 4.8168 6.0718 2.9055 0.4039
LB373-MEL-D GDSC2 5.0135 6.1414 2.9567 0.1874
CHL-1 GDSC2 6.3116 8.5204 2.5998 0.5028
WM115 GDSC2 6.468 17.0541 -1.132 17.179
EquiPSC Line K2 GDSC2 3.4547 5.5352 2.324 5.9427
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 2.8353 6.8934 1.1161 15.3393
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Rh41 GDSC2 1.9178 3.3992 1.7677 14.8855
STS-0421 GDSC2 2.1865 4.3533 1.7032 14.1122
TE 441.T GDSC2 2.6907 3.6509 2.5218 7.2635
RD GDSC2 2.8524 5.8364 1.6547 11.9928
KYM-1 GDSC2 3.011 5.2957 2.0653 8.9076
SW982 GDSC2 3.2426 7.0296 1.4016 12.3356
SW684 GDSC2 3.4048 9.1285 0.4875 17.1602
SK-LMS-1 GDSC2 3.5031 6.2239 2.019 7.7339
G-402 GDSC2 3.5586 6.7813 1.7853 9.0486
GCT GDSC2 3.7422 10.9662 -0.1558 19.4549
Rh30 GDSC2 3.7454 8.6644 0.9948 13.3322
RKN GDSC2 4.1387 5.7109 2.72 1.99
HT-1080 GDSC2 4.3345 6.3532 2.5439 2.6443
G-401 GDSC2 4.4303 14.7035 -1.4736 23.0899
MES-SA GDSC2 4.7129 7.4271 2.28 3.4809
SK-UT-1 GDSC2 4.8364 7.7942 2.1864 3.7951
VA-ES-BJ GDSC2 5.608 12.1453 0.6391 10.894
EW-8 GDSC2 5.8314 9.7714 1.8704 3.9512
A-204 GDSC2 5.9912 8.8114 2.3544 1.5162
SW872 GDSC2 6.2024 17.0593 -1.3194 18.4404
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GCIY GDSC2 2.3358 4.7009 1.703 13.5285
MKN45 GDSC2 2.4423 9.1584 -0.3582 24.4599
ECC10 GDSC2 2.4674 4.093 2.1059 10.6086
IM95 GDSC2 2.5744 5.8828 1.3754 14.6519
NCI-N87 GDSC2 2.7614 7.2736 0.8615 17.0778
SK-GT-2 GDSC2 2.9505 4.45 2.4248 6.861
AGS GDSC2 2.9531 4.9312 2.1924 8.301
RF-48 GDSC2 2.9856 10.1261 -0.3644 22.6931
TMK-1 GDSC2 3.123 4.879 2.372 6.6191
MKN1 GDSC2 3.2488 6.7711 1.536 11.4885
ECC12 GDSC2 3.3295 6.023 1.9777 8.4852
HGC-27 GDSC2 3.4109 5.75 2.1812 6.967
OCUM-1 GDSC2 3.4611 10.2685 -0.0361 19.6905
23132/87 GDSC2 3.538 10.8694 -0.2733 20.5949
RERF-GC-1B GDSC2 3.5839 9.2208 0.5878 16.0904
MKN28 GDSC2 3.6846 7.4466 1.5535 10.1446
NUGC-4 GDSC2 3.7027 10.186 0.2018 17.8
SCH GDSC2 3.9387 7.6257 1.6599 8.8294
MKN7 GDSC2 4.0375 7.27 1.9078 7.0646
KATO III GDSC2 4.1131 7.5078 1.8461 7.2649
SNU-1 GDSC2 4.6502 6.5419 2.6377 1.6739
NUGC-3 GDSC2 4.7114 12.0671 0.0464 15.9205
SNU-5 GDSC2 5.6344 21.6065 -3.9719 27.5148
Hs 746.T GDSC2 6.5725 20.0032 -2.4894 21.6691
SNG-M GDSC2 4.8647 10.3169 1.0118 10.4634
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC2 2.2039 3.6048 2.0143 12.2412
ML-1 [Human leukemia] GDSC2 3.1719 6.2024 1.7548 10.3556
8305C GDSC2 3.3022 7.4171 1.2579 13.0334
K5 GDSC2 3.4271 6.6248 1.7573 9.5903
IHH-4 GDSC2 3.432 4.8183 2.6634 3.8602
ASH-3 GDSC2 3.6721 6.5259 2.0016 7.3906
HTC-C3 GDSC2 3.7468 7.0055 1.8212 8.3229
CAL-62 GDSC2 4.4724 6.4862 2.5645 2.3065
WRO GDSC2 5.2462 11.5527 0.6788 11.4441
FTC-133 GDSC2 5.2779 7.8379 2.4104 1.9999
BHT-101 GDSC2 5.645 14.6296 -0.5324 16.4366
B-CPAP GDSC2 5.9254 14.8935 -0.4641 15.5345
TT2609-C02 GDSC2 6.2592 14.3324 0.0301 12.6052
8505C GDSC2 7.1946 20.1753 -2.1365 19.3507
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-15A GDSC2 2.0412 4.8745 1.3264 16.9141
BB30-HNC GDSC2 2.1045 5.143 1.2693 17.006
SCC-9 GDSC2 2.2543 7.3387 0.3667 21.5737
BB49-HNC GDSC2 2.5081 5.0421 1.7159 12.8072
DOK GDSC2 2.5354 4.7807 1.8655 11.7941
KOSC-2 GDSC2 2.5504 5.2667 1.6501 13.0576
KON GDSC2 2.6021 4.0378 2.2691 9.105
JHU-029 GDSC2 2.6048 4.7944 1.9271 11.1631
JHU-011 GDSC2 2.656 5.0472 1.8565 11.4126
Detroit 562 GDSC2 2.7761 6.4386 1.2883 14.4973
UPCI-SCC-090 GDSC2 2.9753 7.1796 1.0971 15.0018
HSC-2 GDSC2 2.9799 5.0351 2.1659 8.3786
OSC-19 GDSC2 3.0281 5.5689 1.9451 9.6087
PCI-06A GDSC2 3.1506 5.3563 2.1587 7.8782
HO-1-N-1 GDSC2 3.1812 5.3134 2.2066 7.4818
NCI-H3118 GDSC2 3.1843 6.5533 1.5902 11.3457
BICR 22 GDSC2 3.3139 5.1775 2.3875 5.9395
PCI-04B GDSC2 3.3541 5.167 2.4261 5.5794
SAS GDSC2 3.3827 9.9234 0.0717 19.3908
PE/CA-PJ15 GDSC2 3.5779 5.3465 2.5142 4.4164
SKN-3 GDSC2 3.8017 6.3257 2.1987 5.8315
SCC-15 GDSC2 3.9436 6.9193 2.0113 6.6506
HSC-3 GDSC2 3.97 6.6604 2.1571 5.6888
JHU-022 GDSC2 4.1992 12.6583 -0.6368 20.3826
BICR 10 GDSC2 4.2331 13.8452 -1.201 22.5855
SAT [Human HNSCC] GDSC2 4.2661 8.9528 1.2494 10.4909
FaDu GDSC2 4.3972 16.5763 -2.4319 26.3069
BICR 31 GDSC2 4.6219 8.6589 1.6436 7.3481
SCC-4 GDSC2 4.8304 12.2312 0.0534 15.5976
BHY GDSC2 4.8728 10.4548 0.9507 10.7867
CAL-33 GDSC2 5.128 7.7973 2.3497 2.4846
CAL-27 GDSC2 5.136 9.2919 1.6793 6.1206
Ca9-22 GDSC2 5.3174 8.2461 2.2567 2.6995
SCC-25 GDSC2 5.4597 7.4612 2.648 0.8352
LB771-HNC GDSC2 5.5066 13.549 -0.1052 14.8048
OSC-20 GDSC2 5.5191 15.2429 -0.9214 18.3562
HSC-4 GDSC2 5.6057 6.9395 2.8941 0.1399
BICR 78 GDSC2 5.7069 8.6736 2.2753 2.137
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC2 1.9975 6.5488 0.5053 21.7795
RT-112 GDSC2 2.9632 5.2099 2.0646 9.0683
BFTC-905 GDSC2 3.3037 8.6657 0.6348 16.6538
SW1710 GDSC2 3.8547 6.0603 2.3673 4.6596
647V GDSC2 4.3255 6.3329 2.5478 2.6377
639V GDSC2 4.3612 7.9606 1.8012 6.9736
CAL-29 GDSC2 4.4736 7.5912 2.0539 5.2272
T24 GDSC2 4.5548 6.8101 2.4666 2.7091
TCCSUP GDSC2 4.5967 9.3437 1.2959 9.4426
HT-1197 GDSC2 5.3047 16.1996 -1.5484 21.2478
J82 GDSC2 5.3154 8.883 1.9745 4.1763
5637 GDSC2 5.6928 13.314 0.137 13.2459
SW780 GDSC2 5.8889 23.7629 -4.846 28.8676
RT-4 GDSC2 6.5539 18.5127 -1.7776 19.3827
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DSH1 GDSC2 0.1107 4.7132 -0.6411 35.5141
PA-1 GDSC2 1.0233 2.8429 0.926 23.5688
BPH-1 GDSC2 1.9417 6.9202 0.274 23.2161
CAL-39 GDSC2 1.9611 7.052 0.2293 23.3724
OVCA433 GDSC2 2.4062 3.8006 2.1607 10.5398
SKG-IIIa GDSC2 2.5806 7.2952 0.6881 18.6735
JAR GDSC2 2.7105 3.8565 2.4591 7.5481
DoTc2 4510 GDSC2 2.9782 5.9878 1.6928 11.3477
NEC8 GDSC2 2.994 5.4779 1.9598 9.6257
LB831-BLC GDSC2 3.2553 6.6676 1.5932 11.1142
SW954 GDSC2 3.5741 5.2807 2.544 4.2394
JHOS-3 GDSC2 3.5945 6.8513 1.7789 8.9905
OV17R GDSC2 3.6533 6.3152 2.0917 6.8749
PWR-1E GDSC2 3.6951 8.1406 1.2161 12.1646
OVCA420 GDSC2 3.7343 6.2368 2.1922 6.0384
ACC-OV7 GDSC2 3.7359 10.4351 0.1042 18.2006
TC-YIK GDSC2 3.9202 7.2642 1.8245 7.8626
C-33 A GDSC2 3.9222 6.6649 2.1205 6.0264
OMC-1 [Human cervical carcinoma] GDSC2 4.06 6.248 2.4189 3.8942
ME-180 GDSC2 4.0601 6.5561 2.271 4.7885
SKN GDSC2 4.1208 9.2041 1.0172 12.2076
HT-3 GDSC2 4.3285 7.5845 1.96 6.0898
SW756 GDSC2 4.3351 10.106 0.7328 13.2726
UWB1.289 GDSC2 4.4072 6.9377 2.3186 3.803
OVMIU GDSC2 4.4232 11.6971 0.013 16.8052
HEC-1 GDSC2 4.4536 7.6941 1.9918 5.636
PEO1 GDSC2 4.4729 8.0529 1.8333 6.5394
HeLa GDSC2 4.6205 6.4449 2.6637 1.5836
Ca Ski GDSC2 4.6335 9.0675 1.4551 8.4316
HEY GDSC2 4.634 7.7173 2.0978 4.6588
MS751 GDSC2 4.7437 9.6756 1.2377 9.4501
JEG-3 GDSC2 4.7747 6.514 2.7125 1.1759
SiSo GDSC2 4.959 13.1063 -0.2821 16.8837
SW962 GDSC2 5.1407 7.0799 2.6557 1.0617
C-4-I GDSC2 5.6376 7.6408 2.6547 0.6946
SiHa GDSC2 5.8283 16.6037 -1.3637 19.4007
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8070).
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