Details of the Drug

General Information of Drug (ID: DMBLHGP)

Drug Name
Saracatinib
Synonyms H8H; AZD-0530; Saracatinib, AZD-0530, AZD0530; N-(5-Chloro-1,3-benzodioxol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine
Indication
Disease Entry ICD 11 Status REF
Hematologic tumour 2B33.Y Phase 2 [1]
Metastatic colorectal cancer 2B91 Phase 2 [2]
Osteosarcoma 2B51 Phase 2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [1]
Middle East Respiratory Syndrome (MERS) 1D64 Investigative [3]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 542
Logarithm of the Partition Coefficient (xlogp) 4.1
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 10
Chemical Identifiers
Formula
C27H32ClN5O5
IUPAC Name
N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-4-amine
Canonical SMILES
CN1CCN(CC1)CCOC2=CC3=C(C(=C2)OC4CCOCC4)C(=NC=N3)NC5=C(C=CC6=C5OCO6)Cl
InChI
InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)
InChIKey
OUKYUETWWIPKQR-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
10302451
CAS Number
379231-04-6
UNII
9KD24QGH76
DrugBank ID
DB11805
TTD ID
D0M0XB
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Proto-oncogene c-Src (SRC) TT6PKBN SRC_HUMAN Modulator [4]
Tyrosine-protein kinase ABL1 (ABL) TT3PJMV ABL1_HUMAN Modulator [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Biotransformations [5]
Cytochrome P450 2D6 (CYP2D6) OTZJC802 CP2D6_HUMAN Biotransformations [5]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Biotransformations [5]
Cytochrome P450 7A1 (CYP7A1) OT8Z5KLD CP7A1_HUMAN Gene/Protein Processing [6]
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) OTYRXD2T PMYT1_HUMAN Gene/Protein Processing [7]
Neural cell adhesion molecule L1 (L1CAM) OTNWAQ4Y L1CAM_HUMAN Post-Translational Modifications [8]
Tyrosine-protein kinase CSK (CSK) OTP03OD0 CSK_HUMAN Gene/Protein Processing [6]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Hematologic tumour
ICD Disease Classification 2B33.Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Proto-oncogene c-Src (SRC) DTT SRC 7.46E-03 -0.2 -1.24
Tyrosine-protein kinase ABL1 (ABL) DTT ABL1 6.28E-04 0.33 2.07
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 215 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -3.7392 0.4619 -3.762 64.4538
MEC1 CTRP2 3.9861 8.7218 2.7559 18.3525
JM1 GDSC1; CTRP2 4.4579 7.2056 3.8998 12.634
CTV-1 GDSC1 -3.9974 -1.7893 -4.0112 61.9361
NCO2 CTRP2; CCLE -3.1222 -0.6778 -3.1228 61.0327
JURL-MK1 GDSC1; CTRP2 -3.0524 1.5392 -3.1054 59.9834
MOLM-6 CTRP2 -2.6027 0.8338 -2.615 57.4725
LAMA-84 GDSC1; CTRP2 -2.4144 0.3762 -2.4176 56.316
KYO-1 CTRP2 -2.1969 -0.4462 -2.197 54.9041
ALL-SIL GDSC1; CTRP2; CCLE -2.0826 0.6139 -2.0858 54.1239
EM-2 GDSC1; CTRP2; CCLE -1.9529 0.9952 -1.9598 53.2541
MY-M12 GDSC1 -1.5885 1.7799 -2.0706 35.0518
CML-T1 CTRP2 -1.4118 1.4801 -1.4209 49.6765
MEG-01 GDSC1; CCLE -1.1559 2.9428 -1.52 37.0446
EoL-1 GDSC1; CTRP2 -0.9387 2.4405 -0.9711 46.5755
BV-173 GDSC1; CTRP2 -0.6337 3.1795 -0.7061 44.6394
BDCM CCLE -0.4185 2.5357 -0.6149 30.2074
KCL-22 GDSC1; CTRP2; CCLE -0.3589 2.8797 -0.3967 42.758
Ku812 GDSC1; CTRP2; CCLE -0.1445 1.4193 -0.1448 41.2322
Farage GDSC1 -0.116 2.5684 -0.8356 19.0461
K-562 GDSC1; CTRP2 0.1124 3.4664 0.051 39.7
Pfeiffer CTRP2; CCLE 0.2791 3.505 0.2224 38.5819
SU-DHL-4 GDSC1; CTRP2; CCLE 0.5607 3.9839 0.4711 36.8132
Karpas-231 GDSC1 0.6805 2.6539 -0.1062 9.9526
SU-DHL-16 GDSC1 0.8652 3.082 -0.1554 9.6069
NK-92MI GDSC1 1.2886 3.2614 0.0998 6.1194
DoHH2 GDSC1; CTRP2; CCLE 1.2963 3.8099 1.2608 31.7507
Kasumi-1 GDSC1; CTRP2 1.4985 3.9841 1.4586 30.4187
QIMR-WIL GDSC1 1.5991 4.0888 -0.0781 6.5555
SUP-B15 GDSC1; CTRP2 1.617 7.9929 0.5692 32.802
EB1 CTRP2; CCLE 1.6374 9.1743 0.1265 33.9271
PF-382 GDSC1; CTRP2 1.6703 4.9713 1.5152 29.6626
WIL2 NS GDSC1 1.7291 4.3299 -0.1035 6.3807
MLMA GDSC1 1.8151 4.3682 -0.0628 5.8415
MEC-1 CCLE 1.8488 9.0591 -1.0353 23.7805
SU-DHL-6 GDSC1; CTRP2; CCLE 1.8847 5.3376 1.6764 28.4191
P32/ISH GDSC1 1.8858 3.3927 0.4363 2.0813
Peer CTRP2 1.9153 6.1847 1.4991 28.9215
Daudi GDSC1; CTRP2 1.9551 4.3707 1.9031 27.4185
LC4-1 GDSC1 2.1316 8.2002 -1.706 16.3343
Ramos.2G6.4C10 GDSC1 2.1619 5.7957 -0.5123 8.2363
Ri-1 CTRP2 2.2472 5.6998 1.9891 26.1841
GA-10 GDSC1; CTRP2 2.2717 7.1392 1.5836 27.5114
NU-DUL-1 GDSC1; CTRP2 2.276 6.2185 1.2938 18.1223
ALL-PO GDSC1 2.3014 4.7568 0.0634 3.7908
JSC-1 GDSC1 2.3522 4.3393 0.277 2.2866
MOLM-13 GDSC1; CTRP2 2.3605 6.4739 1.899 26.1452
YT GDSC1 2.3754 4.2897 0.3106 2.0418
BALL-1 GDSC1 2.3758 3.9441 0.4551 1.2122
MHH-PREB-1 GDSC1 2.3936 5.3188 -0.1381 4.993
A3/Kawakami GDSC1 2.4121 3.6869 0.5729 0.6098
BE-13 GDSC1 2.4615 13.035 -3.8471 25.3695
Hs 445 GDSC1 2.4702 4.8 0.1402 2.9552
KOPN-8 GDSC1 2.5252 6.8025 -0.7498 8.9738
SEM CTRP2 2.5323 4.9503 2.4453 23.6933
MV4-11 GDSC1; CTRP2 2.5423 5.0885 2.4346 23.6979
Loucy GDSC1 2.6411 4.8658 0.2027 2.2828
CTB-1 GDSC1 2.6664 8.4829 -1.4602 13.2861
WSU-NHL GDSC1 2.6829 5.8964 -0.2286 5.0018
MOLT-4 GDSC1 2.827 4.7216 0.352 1.2232
Jiyoye GDSC1 2.8659 5.1925 0.1788 2.0959
ME1 GDSC1 2.8709 4.0543 0.6184 0.2055
TUR GDSC1 2.9082 4.5004 0.4722 0.6284
CESS GDSC1 2.9111 4.7927 0.3616 1.0915
ROS-50 GDSC1 2.9557 6.611 -0.3919 5.5415
GDM-1 GDSC1; CTRP2 2.96 8.8572 1.2093 21.9032
SCC-3 GDSC1 2.9983 4.035 0.6696 0.0848
MOLM-16 CTRP2 3.011 7.3672 2.2976 22.7667
CCRF-CEM GDSC1 3.0252 4.4188 0.5475 0.3189
Hs 611.T CTRP2 3.0322 7.7101 2.1891 23.1019
BC-3 GDSC1 3.0357 4.3389 0.5794 0.2357
MN-60 GDSC1 3.0568 5.3048 0.2245 1.607
697 GDSC1; CTRP2; CCLE 3.0677 7.0738 2.4662 21.983
IM-9 GDSC1 3.0789 4.2914 0.6112 0.1576
HAL-01 GDSC1 3.0896 7.1168 -0.5423 6.2642
P30/OHK GDSC1 3.1389 9.6358 -1.6917 13.4384
RPMI-8402 GDSC1; CTRP2; CCLE 3.173 6.5182 2.7697 20.5582
Jurkat CTRP2; CCLE 3.1834 12.6108 0.1525 29.2674
NU-DHL-1 CTRP2 3.2098 5.9674 2.9716 19.7152
ML-2 GDSC1 3.2189 5.2784 0.3074 1.0496
SU-DHL-1 GDSC1; CTRP2 3.2461 4.8764 3.2127 18.7553
KMS-21-BM CTRP2 3.2684 4.9621 3.2275 18.6322
KY821 GDSC1 3.2714 4.9185 0.4625 0.4422
NALM-6 GDSC1; CTRP2 3.2811 6.1556 2.9977 19.4038
Kasumi-2 CTRP2; CCLE 3.2922 6.3762 2.9441 19.5652
ARH-77 GDSC1 3.2924 10.3679 -1.9386 14.4569
VAL GDSC1 3.3014 5.1758 0.3805 0.6949
HT GDSC1; CCLE 3.3581 4.8159 2.3704 2.6169
DG-75 GDSC1 3.3965 5.0866 0.45 0.4172
HC-1 GDSC1 3.4156 7.299 -0.4371 4.9558
KMOE-2 GDSC1 3.4504 5.3545 0.3741 0.6225
Karpas-45 GDSC1 3.4565 9.5025 -1.4199 11.0459
BC-1 GDSC1 3.4691 5.2016 0.4365 0.4211
Mono-Mac-1 CTRP2; CCLE 3.5173 8.1026 2.5419 20.4259
H9 GDSC1 3.5556 10.6517 -1.8982 13.5819
CRO-AP2 GDSC1 3.6044 5.1678 0.4977 0.226
U-698-M GDSC1 3.6071 5.4105 0.4141 0.4195
Ki-JK CTRP2 3.6146 5.3871 3.5389 16.4455
RPMI-8866 GDSC1 3.6252 5.3025 0.4587 0.3015
VL51 GDSC1 3.6724 5.6409 0.3566 0.5532
L-540 GDSC1; CTRP2 3.6752 6.8485 3.2019 17.4876
EHEB GDSC1; CTRP2 3.6817 12.282 0.7895 26.1051
JVM-2 GDSC1; CTRP2 3.7062 7.871 2.8361 18.7896
Karpas-299 GDSC1; CTRP2; CCLE 3.7213 5.2112 3.6785 15.6215
EB2 GDSC1; CCLE 3.7833 7.1687 1.5269 6.2274
CA46 GDSC1; CTRP2 3.8629 9.3109 2.3649 20.1727
ATN-1 GDSC1 3.8978 13.1962 -2.8848 17.7154
NCI-H929 CTRP2 3.9065 6.2731 3.645 15.1669
WSU-DLCL2 GDSC1; CTRP2 3.9127 6.0632 3.7129 14.9012
RPMI-6666 GDSC1; CTRP2 3.9253 9.9302 2.141 20.8525
RCH-ACV CTRP2 3.9335 6.645 3.5527 15.4289
KMS-20 CTRP2 3.9404 6.2073 3.7017 14.858
U266B1 GDSC1; CTRP2 3.9408 6.6871 3.5458 15.4333
DEL GDSC1; CTRP2; CCLE 4.0132 5.1153 3.996 13.5897
JVM-3 GDSC1; CTRP2; CCLE 4.015 7.4501 3.3337 16.0323
OCI-Ly10 CTRP2; CCLE 4.0783 7.4717 3.3915 15.6363
DND-41 GDSC1; CTRP2 4.0787 7.4285 3.4097 15.5647
OCI-AML-2 GDSC1; CTRP2; CCLE 4.0899 6.3201 3.8302 13.9415
Mino CTRP2; CCLE 4.1022 6.5222 3.7775 14.1002
SUP-T1 GDSC1; CTRP2; CCLE 4.1764 6.9999 3.6835 14.2428
NKM-1 GDSC1 4.1891 6.1979 0.3524 0.3439
MC116 GDSC1; CCLE 4.1944 5.177 2.6748 0.2569
KE-97 CTRP2; CCLE 4.2065 8.2742 3.1799 16.122
KE-37 GDSC1; CTRP2 4.397 6.1573 4.2145 11.6179
KMS-11 CTRP2; CCLE 4.4678 6.5288 4.1709 11.5706
RPMI-8226 GDSC1; CTRP2 4.4919 8.828 3.2142 15.2618
Namalwa GDSC1; CTRP2 4.5009 10.8862 2.2416 19.0488
KMS-26 CTRP2; CCLE 4.5609 5.8652 4.4706 10.1958
SU-DHL-8 GDSC1; CTRP2; CCLE 4.589 8.9301 3.2621 14.8308
AMO1 GDSC1; CTRP2; CCLE 4.5898 5.9665 4.4775 10.0815
GR-ST GDSC1 4.6075 7.2294 0.1442 0.7077
Granta-519 GDSC1; CTRP2; CCLE 4.6281 11.0486 2.2823 18.5928
MOLT-16 GDSC1; CTRP2; CCLE 4.6286 8.5833 3.4632 13.9255
SR GDSC1; CTRP2 4.6461 6.1223 4.4964 9.8419
OCI-AML-3 GDSC1; CTRP2 4.6508 7.326 4.0509 11.526
P3HR-1 CTRP2; CCLE 4.6827 8.5893 3.5138 13.5887
Karpas-422 GDSC1; CTRP2; CCLE 4.6861 8.3337 3.636 13.0883
TALL-1 [Human adult T-ALL] CTRP2 4.6956 7.6521 3.955 11.7876
RS4;11 GDSC1; CTRP2 4.6996 7.1322 4.1837 10.8763
PL-21 GDSC1 4.764 6.9451 0.3008 0.2767
OPM-2 GDSC1; CTRP2; CCLE 4.7814 8.487 3.6587 12.7621
A4/Fukuda GDSC1; CTRP2 4.8859 6.8272 4.505 9.1225
HDLM-2 GDSC1; CTRP2 4.8912 7.5507 4.1992 10.3129
HuT 78 CTRP2; CCLE 4.8967 19.4749 -1.6498 29.4692
JJN-3 GDSC1; CTRP2 4.9181 7.6453 4.1836 10.3067
SUP-M2 GDSC1; CCLE 4.9305 5.9877 2.6622 0.0741
SUP-T11 CTRP2 4.9801 6.7383 4.6403 8.3416
MOTN-1 CTRP2 4.9933 7.7399 4.2158 9.989
KHM-1B CTRP2; CCLE 5.0016 6.931 4.5834 8.5047
SU-DHL-10 CTRP2; CCLE 5.0156 13.2482 1.5529 20.373
F-36P CTRP2; CCLE 5.0312 7.3295 4.4404 8.9924
L-363 GDSC1; CTRP2; CCLE 5.0521 6.8486 4.6708 8.0278
MHH-CALL-4 CTRP2 5.0598 6.968 4.6282 8.1739
MOLT-3 CTRP2 5.0598 15.3718 0.5367 23.5877
KG-1 GDSC1; CCLE 5.0863 6.9706 2.3688 0.6197
L-428 GDSC1; CTRP2; CCLE 5.1444 6.7932 4.7904 7.3131
KMS-12-BM GDSC1; CTRP2; CCLE 5.1495 6.4405 4.9368 6.7342
SK-MM-2 GDSC1; CTRP2; CCLE 5.1661 7.776 4.37 8.9396
Ci-1 CTRP2; CCLE 5.1736 8.2357 4.1592 9.7818
ST486 GDSC1; CTRP2 5.2181 6.8541 4.8411 6.918
MOLP-8 GDSC1; CTRP2; CCLE 5.22 6.7875 4.8716 6.7933
SET-2 CTRP2 5.2237 6.8087 4.8664 6.8036
DB GDSC1; CTRP2 5.2252 6.9407 4.8107 7.0195
M-07e CTRP2 5.2398 7.0916 4.7586 7.1888
OCI-Ly19 GDSC1; CTRP2 5.2576 9.2466 3.7482 11.2811
LP-1 GDSC1; CTRP2; CCLE 5.2726 6.6448 4.9865 6.2032
P12-Ichikawa CTRP2; CCLE 5.299 10.5354 3.151 13.6419
Reh GDSC1; CTRP2; CCLE 5.303 6.5757 5.0469 5.8859
KM-H2 GDSC1; CTRP2 5.3209 6.9885 4.8871 6.4689
SKM-1 GDSC1; CTRP2 5.3624 5.9716 5.3187 4.6947
MM1.S CTRP2 5.3627 6.4003 5.18 5.2085
SIG-M5 GDSC1; CTRP2; CCLE 5.3744 5.8487 5.3558 4.5269
BL-70 CTRP2; CCLE 5.3764 5.9037 5.3485 4.5459
RL GDSC1; CTRP2 5.3803 5.8927 5.3547 4.5121
JeKo-1 CTRP2 5.3833 9.2472 3.8635 10.5249
EJM GDSC1; CTRP2 5.3902 7.4705 4.7329 6.9205
U-937 CTRP2; CCLE 5.4212 6.088 5.3519 4.3958
OCI-Ly3 CTRP2 5.4634 6.7988 5.1167 5.1879
SUP-HD1 GDSC1; CTRP2 5.476 7.2994 4.8974 6.0435
HEL GDSC1; CTRP2 5.491 6.7153 5.1821 4.8564
JM-1 CCLE 5.4925 7.0604 2.4946 0.1836
KMS-34 CTRP2; CCLE 5.4936 6.04 5.4445 3.8413
MOLT-13 GDSC1; CTRP2 5.4976 8.5554 3.6508 5.3989
KMS-27 CTRP2 5.5052 6.365 5.3454 4.1783
PL21 CTRP2 5.5079 6.0957 5.4442 3.799
OCI-AML-5 GDSC1; CTRP2; CCLE 5.5142 5.9155 5.4952 3.5974
HD-MY-Z CTRP2; CCLE 5.5196 6.7905 5.1773 4.8026
Mono-Mac-6 GDSC1; CTRP2 5.534 12.3767 2.4435 15.9544
Raji GDSC1; CTRP2; CCLE 5.5552 7.1329 5.0533 5.2174
AML-193 CTRP2 5.5569 6.0143 5.5203 3.3749
KO52 CTRP2; CCLE 5.5611 6.0133 5.5251 3.3447
OCI-M1 GDSC1; CTRP2 5.5717 6.9371 5.1615 4.7371
HPB-ALL CTRP2 5.6296 7.2092 5.0883 4.898
THP-1 GDSC1; CTRP2 5.6313 7.0198 5.1807 4.5149
HuNS1 CTRP2 5.6687 6.4243 5.4922 3.1654
KMS-18 CTRP2 5.6849 7.0249 5.2298 4.1875
HEL 92.1.7 CTRP2; CCLE 5.7113 6.2875 5.5945 2.6512
CMK CTRP2 5.7132 6.3326 5.5776 2.7118
MHH-CALL-3 CTRP2 5.7133 10.0239 3.7725 10.2012
HL-60 GDSC1; CTRP2 5.7867 6.3521 5.645 2.2532
TF-1 CTRP2 5.8135 6.3777 5.6606 2.1221
CMK-86 CCLE 5.8255 7.7867 2.3627 0.3168
NB4 GDSC1; CTRP2 5.871 7.7425 4.3062 1.9533
Toledo CTRP2; CCLE 5.9037 7.3862 5.253 3.6084
P31/FUJ GDSC1; CTRP2; CCLE 6.0203 7.7478 5.1725 3.7114
MJ CTRP2; CCLE 6.029 7.6289 5.2392 3.4142
HH [Human lymphoma] GDSC1; CCLE 6.0303 8.2389 2.2789 0.4135
L-1236 GDSC1; CTRP2 6.1434 9.1826 4.557 6.0637
MOLP-2 CTRP2 6.2262 7.3872 5.5178 1.8862
NOMO-1 GDSC1; CTRP2 6.4462 7.9758 4.5169 0.6227
KMM-1 CTRP2; CCLE 6.5327 8.9225 4.9892 3.5772
ME1 CTRP2 6.8321 11.6118 3.8868 7.6474
REC-1 CTRP2 7.0472 9.93 4.8603 3.3417
BL-41 GDSC1; CTRP2; CCLE 7.3824 8.5314 5.6621 0.2598
Karpas-620 GDSC1; CTRP2; CCLE 7.9276 9.5739 5.4953 0.3888
⏷ Show the Full List of 215 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 1.7629 7.9705 0.7339 31.8447
TE8 CTRP2 2.4677 10.0944 0.598 30.0427
TE-15 GDSC1; CCLE -0.9161 3.1127 -1.3051 35.1601
TE-8 GDSC1 -0.1603 1.9678 -0.6177 17.6866
KYSE-140 CTRP2; CCLE 0.7628 8.0105 -0.3549 38.1019
TE-6 GDSC1; CTRP2 1.2065 6.5957 0.6044 34.1028
OE21 CTRP2; CCLE 1.2275 4.9319 1.0442 32.6916
TE-4 CTRP2 1.5019 5.0009 1.328 30.8433
TE-11 GDSC1; CTRP2; CCLE 1.6454 6.049 1.2423 30.65
KYSE-180 CTRP2; CCLE 1.9847 9.1365 0.507 31.7854
TE-14 CTRP2 2.4102 6.777 1.8566 26.1404
KYSE-410 CTRP2; CCLE 2.8582 8.3511 1.7479 25.1863
TE-5 GDSC1; CTRP2; CCLE 2.8802 5.6373 2.6933 21.7253
TE-10 GDSC1; CTRP2 3.1325 8.4667 1.9873 23.5496
OE19 CTRP2 3.2269 5.6055 3.0773 19.2859
KYSE-520 CTRP2; CCLE 3.6113 7.5522 2.8661 18.9371
COLO 680N CTRP2 3.9947 12.2332 1.1111 24.2884
TE-1 GDSC1; CTRP2; CCLE 4.1489 10.9142 1.893 21.2012
OE33 CTRP2; CCLE 4.2538 6.9379 3.79 13.6196
KYSE-30 CTRP2; CCLE 4.2968 8.7615 3.0509 16.3996
KYSE-70 CTRP2; CCLE 4.5318 8.9892 3.1781 15.3077
TE-9 GDSC1; CTRP2; CCLE 5.5711 11.0421 3.141 13.1012
KYSE-450 CTRP2; CCLE 5.9306 12.3566 2.7929 13.7691
KYSE-510 CTRP2; CCLE 6.5498 10.3786 4.2827 6.4834
EC-GI-10 GDSC1; CTRP2 6.7466 12.6311 3.3163 10.1309
KYSE-150 CTRP2; CCLE 7.6395 12.7576 3.9062 6.3229
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.4764 8.8265 3.1995 15.359
HuP-T4 CTRP2; CCLE -0.0012 3.6571 -0.0872 40.516
MZ-PC-1 GDSC1 0.9568 4.265 -0.6686 13.222
SNU-213 CTRP2 1.3474 10.2528 -0.6271 36.6216
Panc 10.05 CCLE 1.7838 6.1126 0.3421 17.6591
KCI-MOH1 CCLE 1.8403 5.9438 0.4772 16.7995
PL45 CCLE 2.4404 6.0197 1.0017 12.29
BxPC-3 CTRP2; CCLE 2.7142 7.4151 1.9614 24.8527
KP-3 CTRP2; CCLE 3.0496 10.749 0.8922 27.4822
PK-1 CCLE 3.0684 6.5118 1.3007 9.0312
Panc 08.13 CTRP2 3.1878 7.699 2.3587 22.033
Panc 03.27 CTRP2; CCLE 3.3203 6.5611 2.9159 19.5849
SW1990 CTRP2; CCLE 3.3791 9.0283 2.0008 22.8155
Capan-1 CTRP2 3.4599 10.3252 1.4965 24.3829
Hs 766T CTRP2; CCLE 3.6346 12.6292 0.5777 26.8677
KP-1N CCLE 3.8126 6.8682 1.6942 5.2899
CFPAC-1 CTRP2 3.9486 9.2711 2.469 19.5543
Panc 05.04 CTRP2 4.0084 11.0251 1.7049 22.2292
KP-1NL CCLE 4.1813 12.0591 -0.5867 15.8376
SU.86.86 CTRP2; CCLE 4.2753 6.6889 3.906 13.119
HuP-T3 CTRP2; CCLE 4.303 9.6183 2.6583 17.9269
PK-59 CTRP2; CCLE 4.3395 8.699 3.1222 16.0097
Capan-2 CTRP2; CCLE 4.425 8.7862 3.1672 15.6156
KP-2 CTRP2; CCLE 4.6119 8.3638 3.5482 13.6258
PK-45H CTRP2; CCLE 4.6206 9.7617 2.8976 16.2115
Panc 04.03 CTRP2; CCLE 4.8126 9.6484 3.1354 14.8051
PaTu 8902 CTRP2; CCLE 4.8487 12.2004 1.9208 19.4315
DAN-G CTRP2 4.9446 9.2053 3.4745 13.1206
YAPC CTRP2 5.0107 9.1792 3.5499 12.6592
Panc 02.03 CTRP2; CCLE 5.0939 7.9848 4.201 9.8018
TCC-Pan2 CTRP2 5.3036 12.4932 2.1835 17.4409
HPAF-II CTRP2; CCLE 5.3201 15.7613 0.5699 22.9196
SUIT-2 CTRP2; CCLE 5.5019 7.3732 4.8873 6.0233
AsPC-1 CTRP2; CCLE 5.5613 10.3785 3.4627 11.8024
QGP-1 CTRP2; CCLE 5.5954 12.1768 2.5965 15.2295
PaTu 8988s CTRP2 5.7186 12.7159 2.4334 15.6092
PaTu 8988t CTRP2 5.8266 15.2432 1.2622 19.6345
PSN1 GDSC1; CTRP2; CCLE 5.9462 9.7364 4.1159 8.2956
HPAC CTRP2; CCLE 6.1495 14.0236 2.142 15.8523
KP-4 CTRP2; CCLE 6.1966 10.8083 3.7881 9.1842
L3.3 CTRP2; CCLE 6.8108 12.1838 3.5877 8.9128
MIA PaCa-2 CTRP2; CCLE 6.8411 16.6696 1.3803 17.2627
SNU-410 CTRP2 8.008 9.9207 5.3965 0.578
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.5356 12.5777 2.3446 16.3319
A-388 GDSC1 1.0623 2.5766 0.263 5.5908
LB2518-MEL GDSC1 1.3649 3.9493 -0.1827 8.0746
SH-4 GDSC1 1.4807 7.2628 -1.7404 18.648
IST-MEL1 GDSC1 2.0507 5.5318 -0.4613 8.1644
CP67-MEL GDSC1 2.19 5.4381 -0.3229 6.7923
LB373-MEL-D GDSC1 2.3995 4.4222 0.2664 2.2752
SK-MEL-1 GDSC1 2.5355 4.437 0.3297 1.6946
CHL-1 CCLE 2.5649 7.0041 0.6247 13.9286
LOX-IMVI GDSC1; CTRP2; CCLE 2.6053 6.0331 2.2943 23.9931
IGR-39 CTRP2; CCLE 2.77 11.4563 0.2879 30.0401
CP66-MEL GDSC1 2.8604 3.9443 0.6524 0.1403
MMAc-SF GDSC1 2.993 4.6142 0.4642 0.5993
Hs 940.T CTRP2 3.0118 10.0279 1.1819 26.6668
GAK GDSC1 3.0166 4.3389 0.5724 0.2592
MZ-MEL-7 GDSC1 3.1559 4.6807 0.5036 0.3797
MZ-MEL-2 GDSC1 3.2121 5.3086 0.2928 1.1194
DJM-1 GDSC1 3.3074 5.0474 0.4299 0.5232
Hs 852.T CTRP2; CCLE 3.6304 11.53 1.0991 25.2589
RPMI-7951 CTRP2; CCLE 3.6585 7.3909 2.9801 18.3724
COLO 679 CCLE 3.6891 5.4851 2.2741 2.5129
SF8657 CCLE 4.2041 7.3222 1.7411 4.3414
Hs 938.T CCLE 4.6581 9.7429 0.8902 7.8418
WM983B CTRP2; CCLE 4.7874 10.5783 2.6603 16.7575
Mel Ho CTRP2; CCLE 4.7888 8.7109 3.5606 13.141
Malme-3M CCLE 4.9793 8.6747 1.5931 3.8766
Hs 934.T CTRP2 5.0139 8.9558 3.6607 12.1983
Hs 895.T CTRP2; CCLE 5.0168 9.6254 3.339 13.506
COLO 741 CCLE 5.1352 7.2868 2.2674 0.9003
WM115 CTRP2; CCLE 5.2182 10.5087 3.0912 14.0614
SK-MEL-5 CTRP2; CCLE 5.2573 8.9647 3.8857 10.7143
MeWo CTRP2; CCLE 5.3078 10.7043 3.0753 13.9295
SK-MEL-3 CTRP2 5.3362 8.2695 4.2979 8.8329
Mel JuSo CTRP2 5.3713 11.9522 2.5124 16.0331
K029AX CTRP2; CCLE 5.3823 5.856 5.3632 4.4762
RVH-421 CTRP2; CCLE 5.422 9.7888 3.6312 11.4029
A101D GDSC1; CTRP2 5.4327 10.1806 3.4468 12.1413
IGR-1 CTRP2 5.4393 6.1895 5.3394 4.388
Hs 936.T CTRP2; CCLE 5.4509 5.9742 5.4144 4.0801
Hs 688(A).T CTRP2 5.4671 5.9907 5.4282 3.9806
IGR-37 CTRP2; CCLE 5.472 12.8885 2.1344 17.2643
HT-144 GDSC1; CTRP2; CCLE 5.4822 14.7193 1.2299 20.4621
SK-MEL-30 CTRP2; CCLE 5.483 5.9513 5.4544 3.8383
COLO 792 CTRP2 5.4922 6.4736 5.2876 4.4378
COLO 829 GDSC1; CTRP2 5.5097 12.2308 2.495 15.8058
A2058 CTRP2; CCLE 5.5626 5.9565 5.5397 3.2887
COLO 800 GDSC1; CTRP2 5.6156 6.1395 5.5474 3.0998
Hs 839.T CTRP2 5.6473 12.7071 2.3766 15.9755
WM88 CTRP2; CCLE 5.6635 10.9007 3.2919 12.2921
IPC-298 CTRP2; CCLE 5.6695 6.1319 5.6084 2.7159
WM266-4 CTRP2; CCLE 5.6921 6.166 5.621 2.6031
UACC-62 CTRP2; CCLE 5.7026 13.5496 2.0033 17.2693
Hs 695T CCLE 5.7154 9.1327 1.7919 2.1469
CJM [Human melanoma] CTRP2 5.7469 6.6088 5.4876 2.9859
A-375 CTRP2; CCLE 5.8314 15.4284 1.1737 19.9211
HMCB CTRP2; CCLE 5.8757 6.5569 5.6369 2.069
G-361 CTRP2; CCLE 5.969 10.6917 3.6576 10.1652
SK-MEL-2 GDSC1; CTRP2; CCLE 6.034 8.2704 4.9227 4.7347
SK-MEL-28 CTRP2 6.1337 7.2235 5.5275 2.0066
WM793 CTRP2; CCLE 6.1651 13.7988 2.2673 15.3498
WT2-iPS CTRP2; CCLE 6.8632 13.563 2.9438 11.4231
UACC-257 GDSC1; CTRP2; CCLE 7.6177 13.4645 3.5496 7.7762
MDA-MB-435S CTRP2; CCLE 7.9533 16.7415 2.1913 12.478
SK-MEL-24 CTRP2; CCLE 8.1587 17.4207 2.0076 12.8176
Hs 944.T CTRP2; CCLE 8.3144 19.6065 1.0496 15.8328
Hs 294T CTRP2; CCLE 9.5795 18.0047 2.691 8.3526
WM1799 CTRP2; CCLE 9.6548 22.1134 0.7835 14.6503
SK-MEL-31 CTRP2; CCLE 11.248 25.8726 0.0595 14.6294
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-12 GDSC1 -1.4949 3.3189 -2.5793 36.6596
HCE-4 GDSC1 2.0146 6.0818 -0.753 10.3786
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 6.6252 8.8597 5.0865 3.0341
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC1 0.3729 5.628 -1.8553 23.5579
CHP-212 CTRP2; CCLE 1.4232 6.2046 0.9565 32.3029
SJNB-6 GDSC1 1.6229 5.8833 -0.944 12.9363
SK-N-BE(2)-M17 GDSC1 1.7206 4.7465 -0.3119 7.9798
SJNB-7 GDSC1 2.0519 7.9237 -1.6291 16.1122
NB(TU)1 GDSC1 2.1626 5.1776 -0.2175 6.0962
KP-N-YS GDSC1 2.2282 4.756 0.02 4.2453
GOTO GDSC1 2.3067 7.1527 -1.0671 11.7322
SJNB-5 GDSC1 2.307 7.6382 -1.303 13.2932
SJNB-10 GDSC1 2.3591 8.1019 -1.4919 14.3462
SJNB-13 GDSC1 2.3688 9.1455 -1.9959 17.3034
KP-N-RT-BM-1 GDSC1 2.5225 5.6179 -0.1973 5.1246
TGW GDSC1 2.5965 4.8446 0.1887 2.4372
SJNB-14 GDSC1 2.6343 5.7642 -0.1973 4.8893
GI-ME-N GDSC1 2.8547 7.076 -0.6665 7.6074
SJNB-17 GDSC1 2.8634 5.4196 0.0819 2.6672
LA-N-6 GDSC1 2.8738 6.5472 -0.4113 5.8403
IMR-5 GDSC1 3.1386 4.5896 0.5294 0.3177
NH-12 GDSC1 3.2851 5.07 0.4129 0.5919
SK-N-DZ GDSC1; CTRP2; CCLE 3.5112 10.9202 1.2704 25.0101
SiMa GDSC1; CTRP2; CCLE 3.8631 9.4598 2.297 20.4286
KP-N-SI9s CTRP2; CCLE 4.4623 11.1895 2.0582 19.8292
IMR-32 CTRP2; CCLE 4.5064 7.2283 3.9415 12.3406
MHH-NB-11 GDSC1; CTRP2 5.2972 7.2274 4.7547 7.0598
NB1 GDSC1; CTRP2 5.4224 5.9586 5.387 4.2659
CHP-126 GDSC1; CTRP2 5.676 17.0413 0.236 23.1603
SK-N-BE(2) CTRP2; CCLE 5.6887 10.6855 3.4212 11.7086
Kelly GDSC1; CTRP2; CCLE 5.767 12.1007 2.7821 14.1423
SK-N-AS CTRP2; CCLE 6.1277 11.1324 3.5695 10.2232
SK-N-SH CTRP2; CCLE 6.2687 12.8058 2.8487 12.888
NH-6 CTRP2 6.468 17.795 0.5182 20.745
KP-N-YN GDSC1; CTRP2 6.5702 8.502 5.2214 2.5664
SK-N-FI GDSC1; CTRP2; CCLE 8.0502 20.0379 0.6408 17.5512
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -1.0675 1.4778 -1.0725 47.3887
SNU-478 CTRP2 0.704 4.8418 0.495 36.2204
SNU-1196 CTRP2 2.4506 8.6083 1.2138 28.1981
SNU-308 CTRP2 2.943 9.7585 1.2323 26.6967
HuCC-T1 CTRP2; CCLE 4.5508 9.2621 3.0682 15.7004
SNU-869 CTRP2 4.71 8.8118 3.4361 13.8356
HuH-28 CTRP2 5.0404 15.9838 0.2151 24.5764
SNU-245 CTRP2 8.5974 21.2807 0.4351 17.2921
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NOS-1 [Human HNSCC] GDSC1 -0.7145 3.0763 -1.6705 27.6667
EW-16 GDSC1 0.4024 4.548 -1.2937 19.9152
ES4 GDSC1 1.5612 5.9759 -1.0372 13.7937
ES6 GDSC1 1.7976 3.9836 0.1091 4.6066
EW-24 GDSC1 2.1009 6.0935 -0.6979 9.7389
ES8 GDSC1 2.2743 4.1632 0.3116 2.1992
SK-PN-DW GDSC1 2.2827 6.5949 -0.8141 10.0593
ES1 GDSC1 2.5102 5.1386 0.0125 3.7208
EW-18 GDSC1 2.7846 4.9585 0.2359 1.8849
EW-13 GDSC1 3.0833 4.9733 0.3664 0.9141
EW-3 GDSC1 3.3658 7.8406 -0.7077 6.7753
EW-1 GDSC1 3.4479 5.4969 0.3205 0.815
EW-22 GDSC1 3.4609 5.8586 0.1879 1.3592
EW-12 GDSC1 3.5534 5.6275 0.3147 0.7636
H-EMC-SS GDSC1 3.6258 6.6718 -0.0614 2.4204
ES7 GDSC1 3.7532 6.156 0.1987 1.0596
G-292 clone A141B1 CTRP2 3.8683 8.7971 2.6026 19.2518
EW-11 GDSC1 4.013 10.4544 -1.5146 10.3626
A-673 CTRP2; CCLE 4.0819 7.376 3.4344 15.4609
MHH-ES-1 CTRP2; CCLE 4.1955 12.8229 1.0133 24.1086
ES5 GDSC1 4.2903 6.7009 0.2125 0.6664
Hs 888.T CTRP2 4.6046 7.9492 3.7297 12.9184
MG-63 CTRP2; CCLE 4.6214 9.3579 3.0913 15.4368
TC-71 GDSC1; CCLE 4.7134 7.0874 2.1457 1.7288
SK-ES-1 GDSC1; CTRP2; CCLE 5.1002 7.2361 4.5523 8.3694
SW1353 CTRP2; CCLE 5.2081 11.5083 2.5877 16.0931
CAL-78 CTRP2; CCLE 5.2691 9.705 3.5337 12.14
SK-N-MC CTRP2 5.2827 9.43 3.6813 11.5013
SJSA-1 GDSC1; CTRP2; CCLE 5.3385 10.4786 3.2146 13.2966
Hs 822.T CTRP2 5.3785 5.8735 5.3562 4.5126
U2OS CTRP2; CCLE 5.5146 9.4891 3.8628 10.2424
TC71 CTRP2 5.5179 7.1763 4.9964 5.5389
SaOS-2 CTRP2; CCLE 6.1706 13.5481 2.3971 14.8438
HOS CTRP2; CCLE 6.7114 11.8743 3.665 8.7662
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 88 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-175-VII CCLE 1.2705 3.18 1.0605 15.8094
HCC1954 CTRP2; CCLE 1.4676 4.8062 1.325 30.967
CAL-51 CTRP2 1.6355 6.1814 1.1947 30.8374
CAL-85-1 CTRP2; CCLE 1.7707 5.9691 1.4007 29.718
EFM-19 CCLE 1.8269 8.6598 -0.8585 23.1165
Evsa-T GDSC1 1.8975 3.6897 0.3091 2.9283
BT-474 GDSC1; CTRP2; CCLE 2.2158 4.9999 2.098 25.9067
HCC2157 GDSC1 2.3161 3.8418 0.4684 1.2151
UACC-812 GDSC1; CCLE 2.5604 6.9515 0.647 13.8248
MRK-nu-1 GDSC1 2.9363 4.2876 0.5607 0.323
Hs 578T CCLE 2.9749 4.8157 2.0711 5.0959
HCC1806 CTRP2; CCLE 3.0461 9.0749 1.638 25.0326
HCC1143 CTRP2 3.0523 10.1552 1.1655 26.6064
ZR-75-1 CCLE 3.1162 5.982 1.6047 7.2749
MDA-MB-468 CTRP2; CCLE 3.2233 7.3165 2.5441 21.2441
MFM-223 GDSC1 3.2939 4.839 0.4993 0.3304
EFM-192A CTRP2 3.4056 8.2476 2.3645 21.4003
HCC2218 GDSC1; CTRP2 3.5533 7.1435 2.9627 18.735
HDQ-P1 CTRP2; CCLE 3.5705 11.7459 0.9385 25.9292
JIMT-1 CTRP2 3.6262 7.0425 3.0785 18.0915
HCC70 CCLE 3.6628 7.1049 1.4703 6.7733
HCC1187 GDSC1; CCLE 3.7093 7.1874 1.464 6.71
HCC1599 GDSC1 3.7502 11.6887 -2.2626 15.0625
OCUB-M GDSC1 3.7529 5.7708 0.3408 0.559
HCC1569 CCLE 4.0254 7.0414 1.7568 4.5706
COLO 824 GDSC1 4.0689 6.1149 0.3375 0.4232
MDA-MB-231 CTRP2 4.1615 11.2017 1.7671 21.6248
Hs 739.T CCLE 4.2487 12.617 -0.8116 16.658
ZR-75-30 CTRP2; CCLE 4.2779 6.2824 4.0467 12.5874
HCC1419 CTRP2 4.3138 6.6537 3.9602 12.8047
SK-BR-3 CTRP2; CCLE 4.3628 6.6785 4.004 12.4992
AU565 CCLE 4.4301 6.8986 2.0741 2.3817
MDA-MB-436 CCLE 4.6922 10.5864 0.5077 11.1386
MDA-MB-453 CTRP2; CCLE 4.818 6.7752 4.454 9.5058
HCC38 CTRP2 4.8203 11.2112 2.3813 17.7666
HCC202 CTRP2 4.8602 8.2256 3.8586 11.7606
HCC1395 CTRP2; CCLE 4.9289 9.4408 3.3459 13.6809
T-47D CTRP2; CCLE 4.93 9.37 3.3812 13.535
MDA-MB-361 CTRP2 5.2098 8.7935 3.9246 10.6615
Hs 578Bst CTRP2 5.3328 10.0631 3.415 12.4882
HCC1500 GDSC1; CTRP2 5.4197 6.3123 5.2745 4.6886
DU4475 GDSC1; CTRP2 5.5075 6.0082 5.4679 3.7146
CAL-148 GDSC1; CTRP2 5.5427 7.3238 4.9502 5.6687
MDA-MB-415 CTRP2; CCLE 5.5479 13.5999 1.8453 18.1718
HCC1428 CTRP2 5.6481 6.2462 5.5439 3.0204
HMC-1-8 CTRP2; CCLE 5.6771 6.0373 5.6455 2.5573
KPL-1 CTRP2 5.6915 9.8696 3.8303 10.7423
BT-549 CTRP2; CCLE 5.9437 10.6825 3.6409 10.2842
HCC1937 CTRP2 6.0508 14.8322 1.6558 17.8199
CAL-120 CTRP2 6.1214 10.0671 4.0968 8.0362
CAMA-1 CTRP2; CCLE 6.6848 8.8634 5.1263 2.7841
MCF-7 CTRP2; CCLE 6.7616 14.4578 2.4194 13.6477
BT-20 CTRP2; CCLE 7.1076 13.6731 3.0758 10.4788
MDA-MB-157 CTRP2; CCLE 8.5589 10.1026 5.5477 0.1288
BT 416 CTRP2 2.9422 6.6142 2.4878 22.2747
BT 139 CTRP2 3.3682 9.0643 1.9738 22.9436
BT 231 CTRP2 4.5086 8.0752 3.5758 13.7767
BT 428 CTRP2 4.7627 7.1644 4.2359 10.5029
BT 159 CTRP2 4.888 9.6112 3.2247 14.2678
BT 330 CTRP2 5.121 7.7952 4.3166 9.2663
BT 145 CTRP2 5.1393 8.1963 4.145 9.9214
BT 112 CTRP2 5.3329 8.0084 4.4208 8.3347
BT 224 CTRP2 5.3689 7.8799 4.517 7.8552
BT 239 CTRP2 5.3773 6.0206 5.3227 4.6348
BT 216 CTRP2 5.4154 6.3843 5.2424 4.8231
BT 248 CTRP2 5.4941 6.7349 5.1766 4.8706
BT164 CTRP2 5.5715 7.5696 4.859 5.9771
BT147 CTRP2 5.5995 6.3053 5.4691 3.442
BT 245 CTRP2 5.6018 6.628 5.3337 3.9681
BT 286 CTRP2 5.6376 6.0914 5.5868 2.89
BT 131 CTRP2 5.671 6.2876 5.5519 2.9259
BT 232 CTRP2 5.7058 6.7205 5.3948 3.4628
BT 504 CTRP2 5.7423 6.3017 5.621 2.4646
BT 172 CTRP2 5.7858 6.4043 5.6206 2.3528
BT 422 CTRP2 5.8701 6.6073 5.6072 2.2043
BT 444 CTRP2 5.9742 6.6102 5.701 1.5849
BT 340 CTRP2 5.9904 6.6148 5.713 1.501
BT 333 CTRP2 6.0142 7.0153 5.5336 2.2059
BT 271 CTRP2 6.027 9.7759 4.1642 7.9351
BT 359 CTRP2 6.0626 7.6038 5.2798 3.1786
BT 482 CTRP2 6.0662 6.972 5.5986 1.832
BT 498 CTRP2 6.1639 7.2088 5.5585 1.823
BT 320 CTRP2 6.1926 7.1465 5.6115 1.553
BT 179 CTRP2 6.8616 12.4409 3.499 9.1885
BT 328 CTRP2 7.5005 8.9249 5.5616 0.4344
BT 440 CTRP2 7.7764 16.9182 1.9747 13.5486
BT 187 CTRP2 7.9565 16.3469 2.3867 11.7527
BT 228 CTRP2 8.0205 17.5279 1.8547 13.5809
⏷ Show the Full List of 88 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 0.9337 3.9418 0.8697 34.2573
Cancer Drug Sensitivity Data Curated from 60 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-336MG GDSC1 -0.9316 1.938 -1.422 27.34
KS-1 [Human Krukenberg tumour] GDSC1 0.1025 3.18 -0.9055 18.5187
KINGS-1 GDSC1 0.8892 5.4114 -1.2987 17.9838
1321N1 CCLE 1.8067 8.8803 -0.9855 23.7047
42-MG-BA CTRP2; CCLE 1.9801 7.4032 1.1756 29.7803
Onda 10 GDSC1 2.2246 4.2384 0.2516 2.673
KG-1-C CTRP2 2.5535 7.0988 1.9023 25.5434
Onda 11 GDSC1 2.8535 4.9637 0.267 1.6267
D-502MG GDSC1 3.1849 5.575 0.1754 1.7108
MOG-G-CCM CCLE 3.1882 6.4596 1.4244 8.076
KNS-81-FD GDSC1 3.2831 5.0506 0.4192 0.5719
D-263MG GDSC1 3.2868 4.7713 0.5203 0.2814
D283 Med GDSC1; CTRP2 3.4882 7.2011 2.8713 19.2643
D-247MG GDSC1 3.554 13.6484 -3.3428 20.5323
SF539 GDSC1; CTRP2 3.6549 7.3365 2.9975 18.3163
M059J CCLE 3.8139 7.6763 1.3006 7.3575
SNU-201 CTRP2 3.86 10.5734 1.7752 22.3561
SF268 GDSC1; CTRP2 3.921 7.0259 3.4007 16.0369
M059K CTRP2 4.3223 8.6552 3.1251 16.0414
DK-MG CTRP2; CCLE 4.3298 9.2401 2.8621 17.062
T98G CTRP2; CCLE 4.472 10.1043 2.591 17.7757
H4 CCLE 4.5471 10.3229 0.5341 9.8194
ONS-76 GDSC1; CTRP2; CCLE 4.756 9.0731 3.357 14.0439
KNS-60 CTRP2; CCLE 4.945 6.8039 4.5768 8.6835
KNS-81 CTRP2; CCLE 4.9626 9.4021 3.3965 13.397
SNB-75 GDSC1; CTRP2 5.0836 10.7961 2.827 15.4225
GMS-10 CTRP2; CCLE 5.0911 11.6652 2.4048 17.063
U-251MG CTRP2 5.1717 8.8487 3.8619 11.0076
GI-1 GDSC1; CCLE 5.1779 13.8557 -0.7373 14.4225
DBTRG-05MG CTRP2; CCLE 5.1926 13.9892 1.3416 20.71
LN-18 CTRP2; CCLE 5.2673 6.5212 5.0313 6.044
LN-229 CTRP2; CCLE 5.3287 12.0447 2.4287 16.4497
SNU-466 CTRP2 5.3347 6.5238 5.1014 5.5885
AM-38 GDSC1; CTRP2 5.3873 7.192 4.8607 6.408
U-118MG CTRP2; CCLE 5.4143 6.8256 5.0549 5.5606
CAS-1 GDSC1; CTRP2; CCLE 5.4627 11.7414 2.6977 15.4268
Hs 683 CTRP2; CCLE 5.7706 12.9711 2.3504 15.8219
GOS-3 CTRP2 5.844 6.4337 5.6651 2.0285
YKG-1 CTRP2; CCLE 5.8946 18.883 -0.5002 24.734
SW1783 CTRP2 6.0062 7.7872 5.141 3.8716
Becker GDSC1; CTRP2 6.062 13.9706 2.0959 16.1971
U-87MG ATCC GDSC1; CTRP2; CCLE 6.2096 7.3637 5.5169 1.9181
GaMG CTRP2; CCLE 6.3239 11.3923 3.5997 9.7289
KALS-1 GDSC1; CTRP2; CCLE 6.4166 17.1265 0.8104 19.9378
NMC-G1 GDSC1; CTRP2 6.6018 13.5349 2.7529 12.6457
GB-1 GDSC1; CTRP2; CCLE 6.6394 16.6096 1.2491 18.0821
SW1088 CTRP2; CCLE 6.66 15.747 1.6961 16.5009
SF295 CTRP2; CCLE 6.6715 8.3909 5.3436 1.9323
Daoy CTRP2; CCLE 6.7523 12.7521 3.2607 10.3462
CCF-STTG1 CTRP2 6.7892 14.8916 2.2252 14.3323
YH-13 CTRP2 6.7902 13.6046 2.8664 11.8585
SNU-738 CTRP2 6.7972 8.5805 5.3354 1.8021
SF126 GDSC1; CTRP2; CCLE 6.9406 16.1648 1.7103 15.9343
SNU-489 CTRP2 7.0717 11.3167 4.2076 5.9461
SNU-626 CTRP2 7.1247 8.7559 5.4478 1.0375
KNS-42 GDSC1; CTRP2; CCLE 7.2574 13.4851 3.2802 9.4155
A-172 CTRP2; CCLE 7.283 13.6633 3.2115 9.6482
TM-31 CTRP2 7.4504 12.7051 3.8006 7.0221
8-MG-BA GDSC1; CTRP2; CCLE 8.3853 14.7835 3.4379 7.1258
SNU-1105 CTRP2 8.8247 21.2999 0.5914 16.4668
⏷ Show the Full List of 60 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 0.1438 1.656 -0.1695 12.8816
ETK-1 GDSC1 1.075 2.9732 0.0752 7.0258
TGBC1TKB GDSC1 1.9149 5.2107 -0.4003 8.0883
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-3 CTRP2 1.3313 4.93 1.1566 31.9764
HEC-1-B CTRP2; CCLE 1.4308 8.8082 0.0557 34.7937
RL95-2 GDSC1; CTRP2; CCLE 2.4032 7.2544 1.685 26.7593
JHUEM-7 CTRP2 2.5033 11.5877 -0.0386 31.6723
EFE-184 CTRP2; CCLE 3.7616 9.0431 2.3841 20.3655
MFE-280 CCLE 3.7693 7.223 1.4902 6.4489
ESS-1 CTRP2; CCLE 4.1254 8.1617 3.1468 16.4638
HEC-251 CTRP2; CCLE 4.2978 10.6399 2.1672 19.8209
HEC-151 CTRP2; CCLE 4.4203 10.9692 2.1252 19.6806
AN3-CA CTRP2; CCLE 4.4311 8.0099 3.5263 14.1722
JHUEM-1 CTRP2 4.475 8.303 3.439 14.407
JHUEM-2 CTRP2; CCLE 4.8956 10.3238 2.8854 15.6157
TEN CCLE 4.9202 11.646 0.1538 12.5175
MFE-296 CTRP2; CCLE 4.9435 7.5782 4.2397 10.0177
HEC-59 CTRP2; CCLE 5.4836 9.8786 3.642 11.2258
MFE-319 CTRP2; CCLE 5.6121 11.5182 2.9393 13.832
EN CTRP2; CCLE 5.6692 6.1945 5.5859 2.801
HEC-1-A CTRP2; CCLE 6.1786 12.3065 3.0245 12.356
HEC-50B CTRP2 6.4457 10.7818 4.0012 7.8389
HEC-265 CTRP2; CCLE 6.5426 9.6611 4.6326 5.0391
KLE GDSC1; CTRP2; CCLE 6.8709 13.8411 2.8116 11.9315
HEC-6 CTRP2; CCLE 7.295 14.2894 2.9121 10.8126
HEC-108 CTRP2 9.8087 21.4844 1.1915 13.1557
Ishikawa (Heraklio) 02 ER- CTRP2; CCLE 8.0423 15.9129 2.6598 10.5966
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB996-RCC GDSC1 -1.108 2.028 -1.6448 29.7334
LB1047-RCC GDSC1 -0.1767 2.344 -0.7969 19.0652
A-704 GDSC1 -0.1119 3.0397 -1.0485 20.5454
TK-10 GDSC1 -0.1042 1.3803 -0.3268 15.3076
RXF 393L GDSC1 0.376 3.7338 -0.9164 17.3844
HA7-RCC GDSC1 0.4558 3.5186 -0.7373 15.7255
CAL-54 CTRP2 0.6046 5.1902 0.3173 37.0897
UO-31 CTRP2 1.3012 5.4467 1.0181 32.5241
BB65-RCC GDSC1 1.3739 4.0312 -0.2164 8.3064
769-P CTRP2; CCLE 1.8624 6.609 1.3147 29.7053
KMRC-1 CTRP2; CCLE 2.3399 5.8348 2.0568 25.6561
KMRC-3 CTRP2 2.8517 10.3386 0.88 28.0781
Caki-2 CTRP2; CCLE 3.3869 8.4342 2.266 21.8188
VMRC-RCW CTRP2; CCLE 3.6576 9.0869 2.2589 21.1119
LB2241-RCC GDSC1 3.7667 5.9158 0.2936 0.7017
786-O CTRP2; CCLE 4.4016 7.6023 3.6743 13.6655
BFTC-909 CTRP2; CCLE 4.9289 8.3559 3.8649 11.5674
TUHR4TKB CTRP2 4.9403 6.5605 4.6676 8.3473
KMRC-2 CTRP2; CCLE 5.0192 14.7578 0.8064 22.8469
KMRC-20 CTRP2 5.03 10.9066 2.7236 15.9536
A-498 GDSC1; CTRP2 5.3165 7.6276 4.5869 7.6931
TUHR10TKB CTRP2 5.3717 6.4016 5.1891 5.1487
TUHR14TKB CTRP2 5.3973 12.0472 2.488 16.0721
VMRC-RCZ CTRP2; CCLE 5.443 12.7605 2.1729 17.1815
OS-RC-2 GDSC1; CTRP2 5.4455 14.4181 1.3485 20.1392
RCC10RGB GDSC1; CTRP2 5.4675 10.1606 3.4877 11.8981
ACHN CTRP2; CCLE 5.727 12.5522 2.5224 15.2466
SNU-1272 CTRP2 7.4067 9.4341 5.305 1.265
Caki-1 CTRP2 8.3752 17.3767 2.1837 11.8504
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT115 CTRP2 -0.012 4.6897 -0.2506 40.95
CCK-81 CTRP2; CCLE 0.2884 5.068 -0.0002 39.1359
SNU-175 CTRP2 0.6649 14.7629 -3.3334 42.5977
GP2d CTRP2 0.8395 7.4992 -0.0905 37.2306
LoVo CTRP2 1.5297 7.6926 0.5861 33.0461
SNU-407 CTRP2 1.6907 8.409 0.4888 32.7847
NCI-H508 CTRP2 1.7547 5.5224 1.4945 29.4562
SW403 CCLE 2.0264 7.5349 -0.1224 19.2054
C2BBe1 GDSC1; CTRP2; CCLE 2.1791 8.5751 0.9409 29.8938
CW-2 GDSC1; CTRP2 2.2123 6.7703 1.6438 27.4902
T84 CTRP2; CCLE 2.2163 7.3789 1.4389 28.1724
NCI-H747 GDSC1; CTRP2; CCLE 2.7257 6.8323 2.1805 24.0337
LS180 CTRP2 2.7468 9.9201 0.9604 28.1303
SNU-C2B GDSC1; CCLE 2.7668 7.9107 0.3477 14.8096
SW1463 CTRP2 2.7719 8.2943 1.6802 25.6741
SK-CO-1 CTRP2; CCLE 2.9273 9.1907 1.4653 25.9634
SW48 CTRP2; CCLE 3.0446 12.8072 -0.0753 30.2463
KM12 GDSC1; CTRP2 3.0877 7.3156 2.3992 22.171
COLO 320HSR GDSC1 3.1396 5.7025 0.1019 2.1579
HT-55 CTRP2 3.3339 10.3263 1.3703 25.1519
SNU-C2A CTRP2; CCLE 3.6502 11.0617 1.34 24.411
SNU-61 CTRP2 3.9915 9.8365 2.25 20.2752
COLO 320 CCLE 3.9929 7.9899 1.2763 7.1253
SNU-1033 CTRP2 4.0655 9.5976 2.4345 19.3869
HCT 15 CTRP2; CCLE 4.1978 8.8529 2.9099 17.2063
SW1417 CTRP2; CCLE 4.4336 12.9853 1.1545 23.0736
LS1034 GDSC1; CTRP2 4.4539 6.7555 4.0733 11.9782
LS123 GDSC1; CTRP2; CCLE 4.6409 9.6263 2.9819 15.8273
COLO 678 CTRP2; CCLE 4.7174 10.2855 2.7369 16.6191
HT-29 CTRP2; CCLE 5.0724 6.0216 4.9898 6.7638
COLO201 CTRP2; CCLE 5.1301 7.0338 4.6722 7.8156
NCI-H716 GDSC1; CTRP2 5.3091 6.8463 4.9383 6.2957
LS513 GDSC1; CTRP2; CCLE 5.4314 6.1691 5.3377 4.4176
DLD-1 CTRP2 5.4772 7.1737 4.9579 5.7943
SNU-C1 GDSC1; CTRP2 5.5538 6.9588 5.1338 4.8929
HCT 8 CTRP2 5.5898 7.3828 4.9667 5.4911
SNU-C4 CTRP2 5.6142 12.7486 2.3274 16.233
RCM-1 [Human ESC] CTRP2 5.6626 8.2006 4.6336 6.7107
OUMS-23 CTRP2 5.6699 6.7025 5.3679 3.6601
CL-11 GDSC1; CTRP2 5.7451 10.1532 3.7356 10.2896
SW948 CTRP2 5.8329 6.5262 5.6106 2.2773
SNU-503 CTRP2 6.0158 8.5748 4.7553 5.4741
HCT 116 CTRP2; CCLE 6.0253 7.1126 5.4943 2.3493
SW480 CCLE 6.0648 13.7536 -0.0875 10.0185
COLO205 CTRP2; CCLE 6.0886 7.1515 5.5272 2.0899
LS411N GDSC1; CTRP2; CCLE 6.0929 6.9419 5.6354 1.6279
MDST8 GDSC1; CTRP2 6.2437 7.3224 5.5629 1.6702
HCC-56 CTRP2; CCLE 6.5353 15.1185 1.9097 15.9677
SNU-C5 CTRP2 6.8991 10.1141 4.6703 4.3197
RKO GDSC1; CTRP2; CCLE 7.7321 14.4168 3.1677 9.1134
SNU-81 CTRP2 8.0366 25.334 -1.9946 24.4103
SW620 CTRP2; CCLE 9.5663 17.0987 3.1037 6.886
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 2.872 4.5406 0.442 0.7743
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 CTRP2 2.1647 6.4337 1.698 27.4527
JHH-5 CTRP2; CCLE 2.3972 6.7941 1.8368 26.2498
SNU-182 CTRP2; CCLE 2.6125 9.0098 1.2163 27.7065
Li-7 CTRP2 2.6616 11.427 0.1932 30.6076
JHH-4 CTRP2; CCLE 2.7846 6.5837 2.3262 23.3321
SNU-449 CTRP2; CCLE 3.1039 5.9015 2.8732 20.3923
JHH-2 CTRP2; CCLE 3.2208 10.0422 1.3866 25.4067
Hep-G2/C3A CCLE 3.8994 7.5417 1.4281 6.5158
JHH-7 CCLE 4.0657 6.19 2.1813 2.3811
SNU-761 CTRP2 4.1544 6.9169 3.6918 14.273
HLE CCLE 4.1787 8.1323 1.3374 6.4519
Hep-G2 CTRP2; CCLE 4.2547 7.6939 3.4828 14.806
HuH-1 CTRP2; CCLE 4.7702 10.5515 2.6573 16.8093
HLF CTRP2; CCLE 4.8477 9.6199 3.1824 14.5333
SNU-423 CTRP2; CCLE 5.0099 7.5466 4.3208 9.5249
SNU-878 CTRP2 5.0615 7.9001 4.209 9.8479
PLC/PRF/5 CTRP2; CCLE 5.6993 7.2538 5.1326 4.5552
SK-HEP-1 CTRP2; CCLE 5.996 6.7271 5.6619 1.7036
SNU-387 CTRP2; CCLE 6.0499 12.9038 2.6193 14.2184
JHH-6 CTRP2; CCLE 6.1519 7.2108 5.5482 1.8872
Hep 3B2.1-7 CTRP2; CCLE 6.308 11.1876 3.689 9.3881
SNU-398 CTRP2; CCLE 6.3608 8.125 5.2546 2.757
SNU-475 CTRP2; CCLE 7.2965 13.1076 3.4942 8.4936
SNU-886 CTRP2 7.4172 8.7422 4.6205 0.0833
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 180 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H3255 CCLE -3.115 -0.8403 -3.1207 52.4989
HCC827 CTRP2; CCLE -2.979 0.3197 -2.9864 59.9562
PC-14 CTRP2; CCLE -1.7461 2.1459 -1.7892 51.847
NCI-H1648 GDSC1; CCLE -1.1191 1.1801 -1.1592 35.5431
HCC4006 CTRP2; CCLE -0.156 4.475 -0.3675 41.8171
Calu-3 CTRP2; CCLE 0.2621 3.1886 0.2279 38.6283
NCI-H1436 GDSC1 0.3547 9.4861 -3.7921 32.0241
NCI-H1693 CTRP2; CCLE 0.6951 8.3021 -0.5349 38.723
HCC2935 CTRP2; CCLE 0.8845 6.3117 0.338 35.9944
NCI-H1650 CTRP2; CCLE 1.1434 9.5052 -0.5287 37.108
LC-2/ad GDSC1 1.2295 3.8544 -0.2407 8.97
NCI-H720 GDSC1 1.3694 2.6939 0.4377 3.2622
CAL-12T CTRP2; CCLE 1.5091 8.0668 0.4258 33.563
SK-LU-1 CTRP2; CCLE 1.5159 7.6098 0.6011 33.0498
NCI-H1435 CTRP2 1.653 5.7054 1.3401 30.3038
NCI-H1793 CCLE 1.6739 6.2072 0.1912 18.7568
NCI-H1836 GDSC1 1.7751 3.2812 0.4223 2.3969
NCI-H1048 CCLE 1.7839 5.6877 0.5447 16.6322
Sq-1 CCLE 1.8007 3.9864 1.3338 12.5379
NCI-H322 CTRP2; CCLE 2.0193 5.4602 1.7964 27.5753
NCI-H345 GDSC1 2.0269 2.8383 0.7328 0.2776
DV-90 CTRP2; CCLE 2.2654 8.3972 1.1037 29.1166
NCI-H1755 CTRP2 2.3773 7.3777 1.6128 27.0869
LXF 289 GDSC1; CTRP2 2.3894 6.149 2.0266 25.6078
NCI-H1304 GDSC1 2.4151 3.926 0.4808 1.0332
NCI-H1975 GDSC1; CTRP2; CCLE 2.4554 5.6746 2.2221 24.7144
NCI-H647 CTRP2; CCLE 2.4556 7.541 1.6371 26.7648
NCI-H2141 GDSC1 2.46 4.3225 0.3399 1.7413
COR-L105 CTRP2; CCLE 2.4686 5.2503 2.3266 24.3075
NCI-H187 GDSC1 2.475 3.8591 0.5338 0.7231
Lu-165 GDSC1 2.4982 4.5825 0.2494 2.2217
NCI-H1734 CTRP2 2.502 7.3731 1.7487 26.2378
NCI-H1666 GDSC1; CTRP2; CCLE 2.5302 6.3261 2.1288 24.8118
NCI-H1703 CTRP2; CCLE 2.6061 8.2251 1.5331 26.6691
NCI-H2170 CTRP2; CCLE 2.6435 6.1989 2.2896 23.892
IST-SL1 GDSC1 2.6484 5.1829 0.0699 3.0931
HCC33 GDSC1 2.6672 4.5571 0.344 1.4457
NCI-H1876 GDSC1 2.7118 4.5493 0.368 1.2695
SW1271 CTRP2; CCLE 2.729 8.1543 1.6914 25.7607
NCI-H1869 GDSC1; CTRP2; CCLE 2.7414 8.252 1.6652 25.8152
LB647-SCLC GDSC1 2.7428 7.3929 -0.8868 9.3626
NCI-H847 GDSC1 2.7547 4.3258 0.4743 0.737
NCI-H1770 GDSC1 2.7602 4.3448 0.4693 0.753
NCI-H2085 CTRP2; CCLE 2.7668 10.4258 0.7548 28.7036
NCI-H209 GDSC1 2.8084 5.4939 0.021 3.1297
NCI-H82 GDSC1 2.8544 4.4199 0.4802 0.6364
NCI-H661 CTRP2; CCLE 2.9095 9.4415 1.3377 26.4435
NCI-H128 GDSC1 2.9295 4.3474 0.5367 0.3958
Ms-1 GDSC1 2.9542 4.8787 0.3471 1.1167
IST-SL2 GDSC1 3.0028 5.9682 -0.0804 3.4374
SBC-1 GDSC1 3.0995 5.5893 0.129 2.0615
EPLC-272H CTRP2 3.2023 8.742 1.9431 23.5134
NCI-H358 CTRP2; CCLE 3.2431 9.3339 1.7269 24.1711
HCC95 CTRP2 3.2499 8.5842 2.0599 22.9572
NCI-H2135 GDSC1 3.2815 4.769 0.5192 0.2861
NCI-H1963 GDSC1 3.3244 5.0229 0.4453 0.4664
COR-L88 GDSC1 3.3267 13.5879 -3.476 21.6451
NCI-H2009 CTRP2; CCLE 3.369 11.4778 0.8692 26.6804
Lu-139 GDSC1 3.3699 5.0148 0.4654 0.3867
LUDLU-1 CTRP2; CCLE 3.3784 8.1096 2.3936 21.3671
NCI-H2030 CTRP2; CCLE 3.3934 8.5204 2.2361 21.912
SK-MES-1 CTRP2; CCLE 3.4157 9.1306 1.9931 22.7439
HCC2279 CTRP2 3.5177 9.4761 1.9423 22.6526
NCI-H2405 CTRP2 3.5724 9.5974 1.9426 22.5052
EBC-1 CTRP2; CCLE 3.6329 5.9033 3.4498 16.7028
NCI-H64 GDSC1 3.6408 4.9736 0.5757 0.0969
CPC-N GDSC1 3.706 5.3264 0.4795 0.232
SW900 CCLE 3.736 6.4453 1.8455 4.644
NCI-H748 GDSC1 3.7704 5.9319 0.2891 0.7144
HOP-62 GDSC1; CTRP2 3.778 8.8437 2.4899 19.9204
NCI-H1838 GDSC1; CTRP2 3.8464 7.0082 3.3275 16.5254
NCI-H510A GDSC1 3.9103 12.0386 -2.323 14.991
HCC366 CTRP2 3.9377 10.9961 1.6505 22.6001
NCI-H322M GDSC1 3.9388 5.9724 0.3393 0.4735
NCI-H2228 CTRP2; CCLE 3.9399 8.1125 2.977 17.616
Lu-134-A GDSC1 3.9583 6.3461 0.2116 0.8641
LCLC-97TM1 CTRP2 4.0588 8.7127 2.8336 17.8615
COR-L23 CCLE 4.1182 6.5867 2.0308 3.0344
LC-1/sq-SF CTRP2; CCLE 4.1665 6.6433 3.8051 13.8108
T3M-10 CTRP2; CCLE 4.1779 8.1881 3.1888 16.1615
NCI-H650 CTRP2; CCLE 4.1818 9.8674 2.4225 19.14
NCI-H1568 CTRP2; CCLE 4.2939 9.0924 2.8953 17.0209
NCI-H1915 CTRP2; CCLE 4.3447 7.6028 3.6151 14.0487
NCI-H520 CTRP2; CCLE 4.3734 8.0422 3.4532 14.6112
COLO 677 CCLE 4.3975 7.0319 1.9953 2.794
NCI-H1373 CTRP2; CCLE 4.4147 8.5379 3.2713 15.2275
A-549 CTRP2; CCLE 4.4362 8.6969 3.2197 15.3789
NCI-H1792 CTRP2; CCLE 4.4601 9.0293 3.0889 15.8403
NCI-H2122 CTRP2; CCLE 4.4665 6.8677 4.044 12.0545
NCI-H2087 CTRP2; CCLE 4.4678 8.3431 3.4135 14.5269
HCC1171 CTRP2 4.5305 14.3274 0.5823 24.6528
NCI-H1563 CTRP2; CCLE 4.5406 10.309 2.5582 17.7386
NCI-H1573 CTRP2; CCLE 4.5416 11.9263 1.7732 20.6821
NCI-H2286 CTRP2; CCLE 4.5443 11.4556 2.0055 19.8289
NCI-H2342 CTRP2 4.5478 8.8565 3.256 14.9563
NCI-H727 CTRP2; CCLE 4.5714 11.2002 2.1554 19.2063
NCI-H524 GDSC1 4.5848 15.2054 -3.383 18.2742
NCI-H1184 CTRP2; CCLE 4.5853 8.2811 3.5596 13.6467
DMS 454 CTRP2 4.6469 7.2722 4.0698 11.4624
SW1573 CCLE 4.7211 11.0266 0.3148 10.5517
NCI-H2110 CTRP2 4.7611 8.505 3.6304 12.9259
NCI-H1623 CTRP2 4.7651 9.5688 3.1284 14.9451
NCI-H292 CTRP2 4.7983 12.4905 1.7319 20.2317
NCI-H838 CTRP2 4.8478 7.4979 4.1787 10.506
NCI-H23 GDSC1; CTRP2; CCLE 4.8751 7.4894 4.2103 10.3099
NCI-H2291 CTRP2 4.995 13.7085 1.3062 21.2685
HCC44 CTRP2; CCLE 5.0479 9.9992 3.1855 14.0598
Hs 229.T CCLE 5.1255 7.4177 2.211 1.0979
HCC1588 CTRP2 5.1668 11.2924 2.6574 15.9099
EKVX GDSC1; CTRP2 5.2648 11.501 2.642 15.7559
HCC15 CTRP2; CCLE 5.2925 12.0201 2.4089 16.6043
NCI-H211 GDSC1; CTRP2; CCLE 5.2928 12.465 2.188 17.4473
HCC78 CTRP2; CCLE 5.2972 7.3216 4.7113 7.2349
NCI-H69 GDSC1; CTRP2 5.2999 6.4633 5.0887 5.733
Lu-99 CTRP2; CCLE 5.3396 10.6211 3.1451 13.5774
NCI-H2126 CTRP2 5.3437 8.7613 4.0654 9.7763
COR-L95 GDSC1; CTRP2 5.3476 7.201 4.8171 6.6829
NCI-H810 CTRP2; CCLE 5.3524 6.1619 5.2542 4.9591
LOU-NH91 CTRP2; CCLE 5.4017 13.8713 1.5832 19.4198
NCI-H1339 CTRP2; CCLE 5.4181 10.1659 3.441 12.1966
Lu-65 GDSC1; CTRP2 5.4298 13.1757 1.9544 18.0233
IA-LM GDSC1; CTRP2; CCLE 5.4346 8.802 4.1294 9.3083
HOP-92 CTRP2 5.4449 8.9463 4.0678 9.5416
NCI-H1105 CTRP2 5.4921 6.6317 5.2201 4.7032
NCI-H1155 GDSC1; CTRP2; CCLE 5.5182 11.0059 3.1126 13.3277
NCI-H2444 CTRP2; CCLE 5.556 14.1605 1.5725 19.1295
COR-L279 CTRP2 5.5581 6.2857 5.4327 3.697
DMS 114 GDSC1; CTRP2; CCLE 5.5833 14.3732 1.4898 19.3608
NCI-H2171 GDSC1; CTRP2 5.5906 6.3302 5.4498 3.5411
NCI-H2196 GDSC1; CTRP2 5.5978 6.621 5.3328 3.9819
LK2 CTRP2 5.6076 6.1626 5.5309 3.185
NCI-H1694 GDSC1; CTRP2; CCLE 5.6169 6.2273 5.5176 3.2081
DMS 53 CTRP2 5.6326 6.6719 5.3449 3.8453
NCI-H2081 GDSC1; CTRP2 5.6417 6.935 5.231 4.2846
RERF-LC-Ad2 CTRP2 5.6485 9.5367 3.9582 9.5612
VMRC-LCD CTRP2; CCLE 5.654 7.282 5.0763 4.8913
MOR/CPR CTRP2; CCLE 5.6876 6.5903 5.4373 3.336
NCI-H2106 CTRP2 5.7001 6.8209 5.3419 3.6923
DMS 79 GDSC1; CTRP2 5.71 6.6081 5.4514 3.2229
NCI-H841 CTRP2 5.7161 6.7512 5.3905 3.4557
NCI-H2029 CTRP2 5.7374 6.7231 5.4245 3.2659
NCI-H1651 CTRP2; CCLE 5.7407 15.9344 0.8441 21.18
HCC1438 CTRP2 5.832 6.7905 5.4823 2.8075
COLO 668 GDSC1; CTRP2 5.845 7.319 5.2341 3.8115
RERF-LC-MS CTRP2; CCLE 5.8745 7.8828 4.98 4.8131
DMS 273 CTRP2 5.9 7.2433 5.3207 3.3327
SHP-77 GDSC1; CTRP2; CCLE 5.9217 6.9501 5.4856 2.597
RERF-LC-Ad1 CTRP2 5.9312 10.7671 3.588 10.5286
NCI-H2023 CTRP2; CCLE 5.9355 10.7882 3.5811 10.5487
BEN CTRP2 5.9514 6.5749 5.6981 1.6458
NCI-H526 GDSC1; CTRP2 5.9796 6.7588 5.6318 1.8633
NCI-H1092 GDSC1; CTRP2; CCLE 6.0011 7.5177 5.2713 3.3341
HARA [Human squamous cell lung carcinoma] CTRP2; CCLE 6.0683 11.9599 3.1065 12.2374
NCI-H1395 CTRP2 6.0802 8.1312 5.0306 4.1926
ChaGo-K-1 CTRP2 6.1983 7.5274 5.4269 2.3135
NCI-H446 GDSC1; CTRP2 6.1996 14.6278 1.8814 16.7158
NCI-H889 CTRP2 6.2285 13.9995 2.2192 15.4083
Calu-6 GDSC1; CTRP2; CCLE 6.2325 13.639 2.4027 14.7024
GLC-82 CCLE 6.2424 9.1468 2.0281 0.9368
NCI-H1299 GDSC1; CTRP2; CCLE 6.2488 14.2307 2.1203 15.7395
NCI-H1581 GDSC1; CTRP2; CCLE 6.2895 7.4008 5.5581 1.6168
SBC-5 CTRP2; CCLE 6.3232 8.2476 5.1657 3.1892
NCI-H2172 CTRP2; CCLE 6.3318 7.5962 5.493 1.8185
NCI-H1944 CTRP2; CCLE 6.341 12.6902 2.9653 12.2852
NCI-H522 CTRP2; CCLE 6.3663 15.9992 1.3326 18.3214
RERF-LC-A1 CTRP2; CCLE 6.404 10.2362 4.2401 6.9162
LCLC-103H CTRP2; CCLE 6.5183 9.2287 4.8278 4.2686
NCI-H441 CTRP2; CCLE 6.5929 13.9022 1.8304 11.3491
NCI-H226 GDSC1; CTRP2; CCLE 6.6114 8.9289 5.043 3.2329
NCI-H1355 GDSC1; CTRP2; CCLE 6.7166 17.3428 0.9451 18.937
Calu-1 CTRP2; CCLE 6.8633 10.8269 4.2966 5.9074
NCI-H1341 CTRP2; CCLE 7.6628 20.5936 0.0706 19.8972
NCI-H460 CTRP2; CCLE 7.9048 9.1377 5.6454 0.1334
HCC2108 CTRP2 8.2461 18.7227 1.4334 14.6755
HCC1195 CTRP2 9.303 17.3194 2.8361 8.1784
HCC1833 CTRP2 9.7695 26.7143 -1.3744 20.3503
KNS-62 CTRP2; CCLE 10.1373 18.0031 3.0336 6.4844
NCI-H196 CTRP2 11.1066 22.9432 1.349 10.9833
COLO 699 CTRP2; CCLE 11.553 24.2981 0.998 11.5305
Hs 888.Lu CTRP2 4.7567 8.553 3.6035 13.0456
⏷ Show the Full List of 180 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 2.4847 7.7711 -1.2423 12.3981
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 2.4043 7.9836 1.414 27.6781
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.4824 12.5186 0.4849 27.537
IGROV-1 CTRP2; CCLE 0.5812 4.8549 0.3598 37.0599
OVCAR-3 CCLE 0.7832 6.155 -0.6642 25.7213
JHOS-4 CCLE 1.5061 9.211 -1.4241 26.3463
OVTOKO CTRP2; CCLE 1.7732 7.9029 0.7703 31.7033
ONCO-DG-1 CTRP2; CCLE 1.968 5.9197 1.6291 28.312
OVCAR-5 CTRP2 2.0614 7.786 1.123 29.6908
SNU-119 CTRP2 2.0753 9.5325 0.4358 31.6999
OVMANA CCLE 2.1975 4.5694 1.476 10.4982
RMG-I CTRP2 2.548 9.6585 0.8712 28.9889
OC 316 CCLE 3.1641 4.3711 2.446 2.6177
COV504 CCLE 3.2696 8.1723 0.6349 12.0684
OC 314 CTRP2; CCLE 3.4277 5.736 3.2666 17.9899
COV318 CCLE 3.5019 6.2571 1.7685 5.523
OAW28 CTRP2 3.5136 8.0366 2.5656 20.3468
OC 315 CCLE 3.5962 5.0878 2.4013 2.0259
OV56 CTRP2 3.6355 6.2703 3.3505 17.0538
OVISE CTRP2 3.8581 7.0972 3.3064 16.5727
FU-OV-1 CTRP2; CCLE 3.8794 15.4412 -0.5611 29.3209
Kuramochi GDSC1; CTRP2; CCLE 3.9871 11.1183 1.6399 22.5126
SNU-840 CTRP2 4.0783 11.5444 1.5228 22.6932
COV434 CTRP2 4.7003 7.1538 4.1753 10.9072
OAW42 CTRP2 4.7274 7.9067 3.8729 12.0339
MCAS CTRP2; CCLE 4.7362 7.4861 4.0698 11.2272
TOV-21G CTRP2; CCLE 4.7406 8.6072 3.5623 13.2511
Caov-3 CTRP2 4.7701 11.5278 2.1798 18.6495
HEY A8 CTRP2; CCLE 4.8565 9.96 3.0259 15.1431
TYK-nu CTRP2; CCLE 4.8729 7.2619 4.3083 9.927
JHOC-5 CTRP2 4.9534 11.9997 2.1149 18.4744
SK-OV-3 CTRP2; CCLE 5.1154 13.9942 1.2711 21.119
EFO-27 CTRP2; CCLE 5.1193 11.1656 2.6771 15.9374
JHOS-2 CTRP2; CCLE 5.2242 8.3476 4.1538 9.6852
COV362 CTRP2 5.2897 11.3159 2.756 15.2506
ES-2 GDSC1; CCLE 5.3369 6.793 2.531 0.165
ES2 CTRP2 5.5305 7.2025 4.9962 5.5094
OV7 CTRP2 5.7891 9.8492 3.9253 9.4086
A2780 CTRP2; CCLE 5.8569 6.9658 5.4195 3.0125
OV-90 CTRP2; CCLE 5.8758 6.6358 5.5986 2.2267
TOV-112D CTRP2; CCLE 6.0113 11.6038 3.2371 11.817
EFO-21 CTRP2; CCLE 6.0399 9.7756 4.175 7.8646
SNU-8 CTRP2 6.2625 13.4078 2.5428 14.1031
JHOM-1 CTRP2 6.6617 9.1782 4.9574 3.5062
COV644 CTRP2 6.712 15.3984 1.9115 15.6313
OVCAR-8 CTRP2; CCLE 6.7396 12.3522 3.4495 9.6008
DOV13 CTRP2; CCLE 6.8407 11.3183 4.0381 7.0094
OVCAR-4 GDSC1; CTRP2; CCLE 7.2483 11.3994 4.2917 5.3398
OVK18 CTRP2 9.773 20.749 1.5192 12.1408
OVSAHO CTRP2; CCLE 9.9596 19.0775 2.43 8.8019
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 3.991 12.2059 1.1208 24.2658
Aska-SS CTRP2 5.0744 11.2058 2.6166 16.276
TE 617.T CTRP2; CCLE 0.1817 4.2425 0.033 39.4765
MFH-ino GDSC1 0.5475 2.7766 -0.2887 11.923
SW872 GDSC1 0.682 4.8521 -1.1971 18.1038
VA-ES-BJ GDSC1 1.722 4.5832 -0.2314 7.3681
SW684 GDSC1 2.0616 6.111 -0.7339 10.1077
A-204 CTRP2; CCLE 3.0492 6.6525 2.5915 21.5779
EW-8 GDSC1 3.3365 4.6729 0.5719 0.1615
GCT CTRP2; CCLE 3.4238 7.6859 2.6142 20.4134
G-401 CTRP2; CCLE 3.6087 7.2363 2.9868 18.4869
G-402 CTRP2; CCLE 3.7004 8.0177 2.7688 19.0629
Rh30 CCLE 4.0119 7.0257 1.7552 4.6028
BT-16 CTRP2 4.4342 10.1973 2.5102 18.181
Hs 729.T CTRP2; CCLE 4.704 6.4191 4.4644 9.789
TTC-709 CTRP2 4.9788 8.7672 3.7177 12.0479
Rh41 CTRP2 5.2669 10.202 3.2867 13.1585
TE 441.T GDSC1; CTRP2 5.4693 6.0458 5.4164 4.0167
HT-1080 CTRP2; CCLE 5.5084 6.9199 5.1069 5.1141
BT-12 CTRP2 5.5312 5.8347 5.5246 3.4412
KYM-1 GDSC1; CTRP2; CCLE 5.6471 6.1846 5.5659 2.9397
MES-SA CTRP2; CCLE 5.6704 6.0788 5.6264 2.6467
Tm87-16 CTRP2 5.7271 6.359 5.5807 2.663
RKN CTRP2; CCLE 5.7353 6.5651 5.4964 2.9788
SK-LMS-1 GDSC1; CTRP2; CCLE 5.7639 7.6547 4.995 4.9839
SK-UT-1 GDSC1; CTRP2 5.8483 7.1465 5.3224 3.4357
SW982 GDSC1; CTRP2 6.33 16.5194 1.0429 19.3573
RD CTRP2; CCLE 7.4943 16.9729 1.7364 14.8691
Rh18 CTRP2 7.8402 18.6859 1.1507 16.2788
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 5.5859 6.6211 5.3207 4.0604
H-STS CTRP2 5.6196 7.7887 4.7971 6.1247
SYO-1 CTRP2 6.8176 17.2342 1.0801 18.3099
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1; CTRP2; CCLE 2.5593 6.7905 2.014 25.1305
IST-Mes2 CCLE 2.9701 5.6778 1.6361 7.4645
MSTO-211H GDSC1; CTRP2; CCLE 3.4284 7.4439 2.7145 20.0233
NCI-H2052 CTRP2; CCLE 4.6926 10.6357 2.5436 17.4349
NCI-H28 CTRP2; CCLE 4.7988 10.3743 2.7703 16.297
NCI-H2452 CTRP2; CCLE 4.9013 10.7678 2.6734 16.4434
ACC-MESO-1 CTRP2 7.2196 13.198 3.3935 9.0219
MPP 89 GDSC1; CTRP2; CCLE 8.8279 22.1553 0.1746 17.6973
JL-1 CTRP2 9.9806 19.7239 2.1408 9.7754
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 CCLE 1.5767 8.5393 -1.0298 24.5954
DU145 CTRP2; CCLE 4.9673 9.0094 3.5905 12.5946
LNCaP clone FGC GDSC1; CTRP2 5.3426 7.9224 4.4714 8.104
22Rv1 CTRP2; CCLE 5.5286 13.8205 1.7186 18.6694
VCaP GDSC1; CTRP2 5.5528 6.2727 5.4319 3.7148
PaCa-3 CTRP2 8.7595 15.1554 3.5039 6.3908
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 0.2468 3.631 0.177 38.8335
A-253 GDSC1; CTRP2; CCLE 4.469 8.0422 3.5505 13.979
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 1.709 6.3764 -1.1227 13.9057
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NUGC-4 CTRP2; CCLE -0.5254 5.2744 -0.9308 44.4669
RERF-GC-1B CCLE 0.8304 4.6743 0.0317 22.3843
NCI-N87 CTRP2; CCLE 0.9959 3.8233 0.946 33.7977
GCIY GDSC1; CCLE 1.0677 4.3461 0.416 19.6776
AZ-521 CCLE 1.1104 5.4952 -0.0357 21.7181
SNU-216 CTRP2 2.0613 4.6551 1.9831 26.8
SNU-668 CTRP2 2.1337 8.0342 1.1061 29.5175
RF-48 GDSC1 2.5545 8.0995 -1.3525 12.9153
Fu97 CTRP2; CCLE 2.9213 6.9565 2.3496 22.8395
GSS CTRP2 2.9547 4.4974 2.9377 20.641
HGC-27 CTRP2; CCLE 3.1378 8.5358 1.9638 23.6196
HSC-39 GDSC1 3.1433 4.8874 0.4236 0.6451
GSU CTRP2 3.4035 6.4526 3.0413 18.8776
IM95 CTRP2; CCLE 3.5904 8.8664 2.2885 21.1807
NUGC-3 CTRP2; CCLE 3.703 6.9677 3.1886 17.458
KATO III CTRP2 3.8886 7.8976 3.0156 17.6044
SNU-620 CTRP2 4.1672 13.7616 0.528 25.6813
KE-39 CTRP2; CCLE 4.47 9.3549 2.9456 16.3855
SNU-1 GDSC1; CTRP2; CCLE 4.8184 8.3521 3.7583 12.2688
MKN74 CTRP2; CCLE 5.12 10.9063 2.8058 15.4258
OCUM-1 CCLE 5.2366 7.2656 2.3199 0.6742
23132/87 CTRP2 5.2424 11.3686 2.6876 15.6248
ECC10 CTRP2 5.286 6.2846 5.1407 5.5751
SNU-16 GDSC1; CTRP2; CCLE 5.3893 6.0149 5.3373 4.5456
HuG1-N CTRP2 5.4003 10.6053 3.2072 13.1935
LMSU CTRP2 5.4319 8.5233 4.2637 8.7573
Hs 746.T CTRP2; CCLE 5.4788 10.0215 3.5668 11.5472
BGC-823 CCLE 5.4904 7.9402 2.169 0.9746
SNU-5 GDSC1; CTRP2 5.5019 6.6799 5.2089 4.722
SNU-719 CTRP2 5.6397 6.9831 5.2063 4.3906
ECC12 CTRP2 5.814 16.2169 0.7649 21.2795
AGS CTRP2 6.0597 13.8274 2.1656 15.9408
MKN7 CTRP2; CCLE 6.0922 10.5508 3.8309 9.204
SH-10-TC CTRP2; CCLE 6.6266 10.8065 4.1295 6.9895
MKN45 CTRP2; CCLE 7.3141 8.4399 5.6682 0.275
SNU-601 CTRP2 7.3772 15.0471 2.5998 11.8866
MKN1 CTRP2 9.0297 19.0596 1.8254 12.8909
SNG-M CTRP2; CCLE 3.4217 7.7715 2.5776 20.557
SNU-685 CTRP2 3.6092 8.1472 2.619 19.8824
SNU-1077 CTRP2 8.1349 19.4858 0.9764 16.3578
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2; CCLE 1.7987 5.7059 1.4988 29.2988
K5 GDSC1 2.201 5.5945 -0.3899 7.2491
TT CTRP2 2.7125 11.1639 0.3649 29.991
B-CPAP CTRP2; CCLE 3.5908 7.8182 2.7369 19.4849
CGTH-W-1 GDSC1; CTRP2 3.7912 7.9664 2.885 18.371
BHT-101 CTRP2 4.1256 5.4324 4.0801 12.9377
ML-1 [Human leukemia] CTRP2 4.2529 12.475 1.2366 23.2367
CAL-62 CTRP2 4.4619 10.3844 2.4468 18.3587
8505C CTRP2; CCLE 4.9416 8.5365 3.7918 11.8346
FTC-238 CTRP2 5.3345 9.1134 3.8844 10.5462
8305C CTRP2; CCLE 5.427 14.303 1.39 20.0368
TT2609-C02 CTRP2; CCLE 5.9838 13.5067 2.2626 15.7259
FTC-133 CTRP2 7.6974 11.4372 4.5695 3.6403
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-10B CTRP2 -0.5694 4.5239 -0.8225 44.5208
BB30-HNC GDSC1 -0.2327 1.3688 -0.4614 16.9486
SNU-1214 CTRP2 0.3504 3.9696 0.2496 38.2369
SNU-1076 CTRP2 0.411 5.3844 0.0633 38.4956
BB49-HNC GDSC1 1.5666 10.0129 -3.0434 24.9811
CAL-27 CTRP2; CCLE 1.6461 6.0606 1.24 30.6552
PE/CA-PJ49 CTRP2 1.9341 6.7983 1.3323 29.4168
CAL-33 CTRP2 1.9534 6.3648 1.4883 28.8357
BHY CTRP2 2.0509 5.329 1.8586 27.2605
SCC-25 CTRP2; CCLE 2.124 4.9543 2.0067 26.5162
LB771-HNC GDSC1 2.2011 5.7854 -0.4809 7.9066
BICR 18 CTRP2 2.277 8.6728 1.0047 29.393
BICR 56 CTRP2 2.2924 8.3825 1.138 28.924
PE/CA-PJ34 (clone C12) CTRP2 2.3078 6.637 1.7906 26.6865
PE/CA-PJ15 CTRP2 2.657 8.5091 1.4715 26.7279
Detroit 562 CTRP2; CCLE 2.8712 7.7271 2.011 24.2135
SNU-46 CTRP2 3.0196 12.8765 -0.1324 30.4608
BICR 31 CTRP2 3.0801 10.3481 1.106 26.7212
SCC-9 CTRP2; CCLE 3.148 8.7518 1.8826 23.8823
SCC-15 GDSC1 3.2691 5.6237 0.1946 1.5213
YD-8 CTRP2 3.6474 8.3991 2.5511 20.0367
HSC-3 CTRP2 3.6592 6.8542 3.1826 17.6059
HSC-4 CTRP2 3.7537 11.2353 1.3586 24.0793
PE/CA-PJ41 (clone D2) CTRP2 3.9069 11.2652 1.4925 23.2294
HSC-2 CTRP2; CCLE 3.9997 8.113 3.0386 17.2176
BICR 6 CTRP2 4.4101 12.314 1.4616 22.0936
SNU-899 CTRP2 4.4531 6.7399 4.0783 11.9619
SNU-1041 CTRP2 4.5535 13.1125 1.2021 22.6322
BICR 22 CTRP2 4.5788 6.9304 4.1388 11.3794
Hs 840.T CCLE 4.6949 10.7583 0.4264 10.062
FaDu CTRP2; CCLE 4.7878 10.4133 2.7411 16.438
BICR 16 CTRP2 4.9518 9.5257 3.3264 13.7074
SNU-1066 CTRP2 6.2354 11.3004 3.5738 10.0009
SCC-4 CTRP2 6.7671 14.4591 2.4231 13.6237
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-BLC1 CTRP2 -0.6957 1.5551 -0.6985 44.9106
RT-4 CTRP2; CCLE -0.1716 3.6293 -0.2642 41.6531
253J CTRP2 0.6861 3.5141 0.6467 35.8254
VM-CUB-1 CTRP2 1.8161 7.3857 1.0048 30.8491
5637 CTRP2; CCLE 1.8596 6.5398 1.3331 29.6537
SCaBER CTRP2; CCLE 2.0848 6.1373 1.6974 27.707
253J-BV CTRP2 2.1869 6.4729 1.7103 27.3409
SW1710 CTRP2 2.297 7.8576 1.348 28.2257
CAL-29 CTRP2 2.4644 7.0274 1.8308 26.0649
HT-1376 CTRP2; CCLE 3.2598 10.5279 1.2037 25.9074
SW780 CCLE 3.4758 6.3405 1.7078 5.9025
JMSU-1 CTRP2; CCLE 3.8589 7.3415 3.2123 16.9287
KU-19-19 CTRP2 4.3567 13.4417 0.8597 24.2084
RT-112 CTRP2; CCLE 4.8301 10.7052 2.6381 16.7459
BC-3C CTRP2 4.9573 8.5295 3.8104 11.7208
BFTC-905 CTRP2 5.0252 6.0722 4.9244 7.1437
647V CTRP2 5.2649 8.7648 3.9903 10.2652
KMBC-2 CTRP2; CCLE 5.4853 10.1925 3.4878 11.8599
UM-UC-1 CTRP2 5.5869 6.8254 5.2286 4.4281
HT-1197 CTRP2; CCLE 5.7811 6.6709 5.4916 2.8871
639V CTRP2; CCLE 5.7823 15.5479 1.0725 20.3566
UM-UC-3 CTRP2; CCLE 5.9267 12.1978 2.8691 13.4732
T24 CTRP2; CCLE 6.1194 12.7207 2.7685 13.4939
J82 CTRP2; CCLE 6.1947 7.7476 5.3146 2.7894
TCCSUP CTRP2; CCLE 7.3273 15.3748 2.4004 12.7283
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCC-IT GDSC1 -0.4195 5.1643 -2.3578 29.8147
KGN GDSC1 0.0555 4.0276 -1.3584 21.8774
SW962 GDSC1 0.8055 2.762 -0.0479 8.9954
SW954 GDSC1 1.0987 3.9211 -0.3791 10.4949
DSH1 GDSC1 1.9464 3.7631 0.3048 2.8562
OMC-1 [Human cervical carcinoma] GDSC1 2.2425 3.9338 0.3934 1.7465
JAR GDSC1 2.5017 6.6986 -0.7159 8.7986
LB831-BLC GDSC1 2.788 5.4202 0.042 3.0321
NT2-D1 GDSC1 3.8849 5.495 0.485 0.1769
NEC8 GDSC1 6.0257 22.9039 -6.0993 24.0192
HeLa CTRP2 6.0924 7.2109 5.5006 2.1948
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug

References

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