Details of the Drug

General Information of Drug (ID: DMBLID9)

Drug Name
N-acetylcysteine
Synonyms
N-Acetyl-L-cysteine; acetylcysteine; 616-91-1; N-Acetylcysteine; mercapturic acid; Acetadote; L-Acetylcysteine; Broncholysin; Fluimucil; Mucomyst; N-Acetyl-cysteine; Parvolex; Fluprowit; Acetein; Airbron; Fabrol; Flumucetin; Mucosolvin; Fluimucetin; Mucosil; Brunac; Fluimicil Infantil; Acetylcysteinum; Acetilcisteina; Respaire; Mucofilin; Lysomucil; Exomuc; Inspir; Ac-Cys-OH; Mucolyticum Lappe; Mucolytikum Lappe; N-Acetyl cysteine; Mucolyticum; LNAC; N-Acetyl-3-mercaptoalanine; N-Acetyl-L-(+)-cysteine; Neo-fluimucil; NAC-TB; Mucolyticum-Lappe; (R; Acetylcysteine
Indication
Disease Entry ICD 11 Status REF
Cystic fibrosis CA25 Approved [1]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [2]
Affected Organisms
Humans and other mammals
ATC Code
R05CB01: N-acetylcysteine
R05CB: Mucolytics
R05C: EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
R05: COUGH AND COLD PREPARATIONS
R: RESPIRATORY SYSTEM
R05CB01: N-acetylcysteine
R05CB: Mucolytics
R05C: EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
R05: COUGH AND COLD PREPARATIONS
R: RESPIRATORY SYSTEM
S01XA08: N-acetylcysteine
S01XA: Other ophthalmologicals
S01X: OTHER OPHTHALMOLOGICALS
S01: OPHTHALMOLOGICALS
S: SENSORY ORGANS
V03AB23: N-acetylcysteine
V03AB: Antidotes
V03A: ALL OTHER THERAPEUTIC PRODUCTS
V03: ALL OTHER THERAPEUTIC PRODUCTS
V: VARIOUS
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C5H9NO3S
Canonical SMILES
CC(=O)NC(CS)C(=O)O
InChI
1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
InChIKey
PWKSKIMOESPYIA-BYPYZUCNSA-N
Cross-matching ID
PubChem CID
12035
ChEBI ID
CHEBI:28939
CAS Number
616-91-1
UNII
WYQ7N0BPYC
DrugBank ID
DB06151
TTD ID
D05NEK
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 12.7867 23.3723 6.207 21.2169
A-673 GDSC2 10.5313 16.4402 7.8586 20.2047
HuO-3N1 GDSC2 11.4609 17.913 7.8957 17.2213
H-EMC-SS GDSC2 11.4808 16.9496 8.3915 14.4943
SK-ES-1 GDSC2 11.7982 18.8427 7.6977 17.3045
CADO-ES1 GDSC2 11.8337 19.6373 7.3304 18.9658
SK-PN-DW GDSC2 11.9044 20.2762 7.0679 19.9565
HuO9 GDSC2 11.9618 14.5871 9.9027 4.3249
EW-3 GDSC2 12.0475 14.9831 9.7713 4.9318
TC-71 GDSC2 12.0833 26.1548 4.2813 28.6994
ES1 GDSC2 12.1176 15.8578 9.4004 6.9955
CAL-72 GDSC2 12.1527 20.8877 6.956 19.7965
EW-1 GDSC2 12.179 14.3552 10.1435 2.5599
EW-18 GDSC2 12.1823 15.3736 9.6745 5.2346
NY GDSC2 12.2321 14.8331 9.9579 3.5031
G-292 clone A141B1 GDSC2 12.3959 18.447 8.3397 12.4639
EW-24 GDSC2 12.4626 22.0758 6.6036 20.4753
CHSA8926 GDSC2 12.5154 16.9376 9.1516 7.6192
ES7 GDSC2 12.6278 16.9716 9.2094 7.0598
HOS GDSC2 12.638 14.1778 10.4485 0.6189
ES8 GDSC2 12.6547 18.7204 8.3899 11.6007
U2OS GDSC2 12.7233 17.0887 9.2158 6.8363
CAL-78 GDSC2 12.7293 27.448 4.1443 27.5653
ES6 GDSC2 12.7404 19.9118 7.8716 14.1086
EW-7 GDSC2 12.7692 14.245 10.4777 0.4448
EW-22 GDSC2 12.7745 14.9027 10.2223 1.3965
SaOS-2 GDSC2 12.8473 14.4877 10.4188 0.5797
EW-16 GDSC2 12.9873 14.9512 10.3009 0.8888
ES4 GDSC2 13.0482 21.8195 7.1613 16.7536
SJSA-1 GDSC2 13.0499 14.5966 10.4599 0.3566
NOS-1 [Human HNSCC] GDSC2 13.1481 15.4509 10.176 1.2353
EW-13 GDSC2 13.3058 15.0768 10.3853 0.4319
EW-11 GDSC2 13.712 16.4675 10.0282 1.3347
MG-63 GDSC2 13.7515 24.8342 6.1937 19.1258
MHH-ES-1 GDSC2 15.0765 26.2702 6.4085 15.7343
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC2 12.0418 15.9293 9.3135 7.6821
OACM5.1 C GDSC2 12.0903 19.3525 7.6687 16.6874
ESO-51 GDSC2 12.1985 22.0062 6.4363 21.7841
KYSE-220 GDSC2 12.4368 18.8037 8.1949 13.1455
OACP4 C GDSC2 12.5311 16.0119 9.5973 5.02
KYAE-1 GDSC2 12.7703 14.4884 10.3858 0.7442
ESO-26 GDSC2 12.9728 18.0914 8.9046 8.1022
FLO-1 GDSC2 13.2112 17.7123 9.2294 5.8737
SK-GT-4 GDSC2 13.2919 21.9687 7.2617 15.7663
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 13.3427 15.1203 10.3838 0.4191
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-5 GDSC2 10.3923 22.3388 4.7945 31.8457
SK-N-SH GDSC2 10.9012 18.1007 7.3444 21.5526
SK-N-FI GDSC2 11.4067 16.0636 8.7744 12.4888
SK-N-AS GDSC2 11.605 23.6173 5.1645 27.5452
Kelly GDSC2 11.7006 21.7992 6.1486 24.1394
SiMa GDSC2 12.0268 13.8307 10.2911 1.999
NB69 GDSC2 12.0463 14.3072 10.0866 3.0981
GOTO GDSC2 12.193 18.2018 8.3126 13.0953
CHP-212 GDSC2 12.2158 19.7105 7.5864 16.7712
SK-N-DZ GDSC2 12.2233 22.9235 5.9999 23.3209
SJNB-13 GDSC2 12.2332 15.8298 9.4916 6.2111
NB1 GDSC2 12.2808 17.1552 8.8867 9.6592
SJNB-14 GDSC2 12.3673 13.8968 10.4383 0.8756
TGW GDSC2 12.3849 13.9703 10.4168 0.9482
SK-N-BE(2)-M17 GDSC2 12.5698 14.2552 10.3882 0.8965
NH-12 GDSC2 12.7256 22.3932 6.6441 19.6807
SJNB-7 GDSC2 12.7338 20.2396 7.707 14.9378
SJNB-10 GDSC2 12.8694 14.4442 10.4443 0.4881
KP-N-YN GDSC2 13.2108 15.3089 10.2595 0.8719
GI-ME-N GDSC2 13.334 21.5974 7.4708 14.7226
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 12.8464 14.7771 10.3065 0.9805
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 824 GDSC2 9.6571 14.1516 8.1839 21.5314
EFM-19 GDSC2 11.5025 19.8156 6.9798 21.4248
MDA-MB-468 GDSC2 11.8049 13.465 10.3269 2.1589
HCC1187 GDSC2 11.915 25.7463 4.3509 28.929
CAL-120 GDSC2 11.9171 13.7157 10.2794 2.2359
CAL-85-1 GDSC2 11.9477 14.7185 9.8311 4.7783
Hs 578T GDSC2 11.9584 16.6468 8.9041 10.31
BT-549 GDSC2 11.9756 19.0618 7.7255 16.7019
HCC1937 GDSC2 11.9973 22.9323 5.819 24.5084
HCC1954 GDSC2 12.0604 14.8615 9.8372 4.5173
MDA-MB-453 GDSC2 12.0626 15.9627 9.3118 7.6454
HCC1419 GDSC2 12.0748 19.7678 7.4514 17.7724
MDA-MB-361 GDSC2 12.116 14.7476 9.9259 3.8941
MFM-223 GDSC2 12.1842 19.702 7.5669 16.9445
DU4475 GDSC2 12.2196 14.0081 10.3187 1.586
MCF-7 GDSC2 12.2597 21.1761 6.8948 19.7855
BT-474 GDSC2 12.2678 16.3448 9.2688 7.4541
MRK-nu-1 GDSC2 12.2821 14.3591 10.1999 2.105
HCC1395 GDSC2 12.3181 15.5794 9.665 5.0267
OCUB-M GDSC2 12.3414 17.4383 8.7919 10.067
HCC2157 GDSC2 12.3471 14.3956 10.2192 1.9161
CAL-51 GDSC2 12.4501 23.1342 6.07 22.5158
HCC1500 GDSC2 12.5177 19.112 8.1024 13.4427
MDA-MB-231 GDSC2 12.5224 15.1714 9.9748 2.938
HCC38 GDSC2 12.5316 17.3485 8.9662 8.6523
UACC-812 GDSC2 12.5389 14.1716 10.4073 0.8478
MDA-MB-157 GDSC2 12.5535 21.3842 7.0133 18.556
AU565 GDSC2 12.6192 16.0133 9.6506 4.5618
MDA-MB-175-VII GDSC2 12.6221 14.468 10.3269 1.099
MDA-MB-436 GDSC2 12.6702 14.8321 10.2004 1.608
HCC70 GDSC2 12.6944 16.3851 9.5254 5.1337
EFM-192A GDSC2 12.7387 14.3145 10.439 0.5832
CAMA-1 GDSC2 12.8042 14.0738 10.5534 0.2359
HDQ-P1 GDSC2 12.8377 14.6608 10.3483 0.8296
ZR-75-30 GDSC2 12.8718 24.5783 5.6753 22.8767
CAL-148 GDSC2 12.9366 14.1912 10.561 0.1788
BT-20 GDSC2 13.018 14.5506 10.4641 0.3598
Evsa-T GDSC2 13.0651 23.2496 6.4735 19.567
JIMT-1 GDSC2 13.2852 21.1997 7.6291 14.0848
MDA-MB-415 GDSC2 13.3525 21.6347 7.4656 14.7073
HCC1806 GDSC2 13.3665 27.0182 4.8419 24.3414
HCC1143 GDSC2 13.4213 16.974 9.677 3.2059
T-47D GDSC2 13.816 26.0325 5.6555 20.8801
HCC1428 GDSC2 14.4938 27.1416 5.596 19.7164
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H4 GDSC2 10.7761 18.2556 7.1616 22.762
U-87MG ATCC GDSC2 11.312 21.4513 6.0087 25.6842
D283 Med GDSC2 11.6014 13.2955 10.2785 2.8132
NMC-G1 GDSC2 11.7048 21.1774 6.462 22.9688
GI-1 GDSC2 11.7116 20.5007 6.8047 21.588
KS-1 [Human Krukenberg tumour] GDSC2 11.7929 15.2276 9.4787 7.2502
ONS-76 GDSC2 11.7986 14.0689 10.0414 3.828
D-263MG GDSC2 11.903 16.8995 8.7392 11.4079
SK-MG-1 GDSC2 11.9482 18.1907 8.1358 14.6584
U-251MG GDSC2 11.9669 16.4353 9.0138 9.6421
MOG-G-CCM GDSC2 12.0329 15.7621 9.3882 7.2538
M059J GDSC2 12.0403 14.5104 9.9889 3.6696
LN-405 GDSC2 12.0735 15.5266 9.5294 6.3196
DBTRG-05MG GDSC2 12.0971 14.981 9.8046 4.6374
LN-18 GDSC2 12.2003 22.844 6.0215 23.3026
42-MG-BA GDSC2 12.2755 14.5456 10.1136 2.5711
8-MG-BA GDSC2 12.2916 19.6129 7.6913 16.0722
SW1783 GDSC2 12.3363 21.086 6.9975 19.1569
YH-13 GDSC2 12.3446 18.2149 8.4162 12.1672
CAS-1 GDSC2 12.4042 13.8889 10.4584 0.7623
Daoy GDSC2 12.4358 18.6335 8.2773 12.7074
AM-38 GDSC2 12.4998 14.4306 10.2832 1.4185
LNZTA3WT4 GDSC2 12.5804 18.4898 8.4496 11.4425
DK-MG GDSC2 12.6055 22.9487 6.28 21.3755
U-118MG GDSC2 12.6385 21.0437 7.2438 17.3359
D-392MG GDSC2 12.6486 20.9595 7.2926 17.0912
GaMG GDSC2 12.6566 19.907 7.814 14.59
KINGS-1 GDSC2 12.6832 19.824 7.8736 14.2301
MOG-G-UVW GDSC2 12.8025 15.3126 10.0649 2.093
PFSK-1 GDSC2 12.8189 14.4858 10.4077 0.6345
SF268 GDSC2 12.8547 19.7056 8.0524 12.9331
SF539 GDSC2 12.9687 14.2702 10.5452 0.1988
KALS-1 GDSC2 13.0991 15.7589 10.027 1.9238
SW1088 GDSC2 13.2759 21.1145 7.6638 13.9393
GB-1 GDSC2 13.8053 22.8715 7.1809 15.039
Becker GDSC2 14.3391 21.6777 8.0919 9.7978
A-172 GDSC2 14.433 26.9807 5.6315 19.7169
T98G GDSC2 14.6009 26.4595 5.9992 18.1248
LN-229 GDSC2 14.9663 32.5217 3.3127 25.1184
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC2 11.8237 16.5599 8.8475 10.9721
ETK-1 GDSC2 12.7767 15.362 10.0303 2.2948
TGBC24TKB GDSC2 12.965 14.9685 10.2843 0.9682
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EN GDSC2 11.968 13.6993 10.3163 1.9537
ESS-1 GDSC2 12.3094 14.9668 9.9431 3.4534
MFE-296 GDSC2 12.3418 14.4373 10.1982 2.0297
RL95-2 GDSC2 12.6161 18.0842 8.6704 10.1445
MFE-280 GDSC2 12.631 17.5683 8.9279 8.6616
KLE GDSC2 13.0454 15.005 10.3053 0.8296
MFE-319 GDSC2 14.0881 29.0042 4.3979 24.0878
AN3-CA GDSC2 14.1057 29.0424 4.392 24.0688
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 130 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SU-DHL-5 GDSC2 9.0493 12.7723 8.2056 23.8406
OCI-M1 GDSC2 9.4635 30.7389 -0.199 41.2951
KOPN-8 GDSC2 10.1551 22.5504 4.4847 33.2571
VAL GDSC2 11.0873 12.958 10.0691 5.3339
MOLT-16 GDSC2 11.0885 12.7837 10.157 4.7752
A3/Kawakami GDSC2 11.1569 13.8595 9.675 7.6305
CML-T1 GDSC2 11.2573 15.363 9.0051 11.5146
P30/OHK GDSC2 11.4314 23.913 4.876 28.7924
BC-1 GDSC2 11.4696 22.2013 5.7622 26.0762
GA-10 GDSC2 11.4971 14.2302 9.7524 6.2665
MOLT-13 GDSC2 11.5421 24.4222 4.7116 28.9407
U-698-M GDSC2 11.5983 20.7415 6.5945 22.7425
GDM-1 GDSC2 11.6312 21.1789 6.4026 23.3925
MM1.S GDSC2 11.6462 21.6929 6.1582 24.2501
NKM-1 GDSC2 11.6717 19.181 7.4306 18.9344
WIL2 NS GDSC2 11.6978 20.7637 6.6627 22.2021
EJM GDSC2 11.7222 17.4562 8.3274 14.2044
L-363 GDSC2 11.7427 17.8585 8.1436 15.151
DB GDSC2 11.7657 16.9993 8.5869 12.6312
IM-9 GDSC2 11.7927 24.2641 4.9925 27.5536
KM-H2 GDSC2 11.8135 15.3507 9.4334 7.4785
WSU-DLCL2 GDSC2 11.8194 13.1861 10.4604 1.4101
SU-DHL-10 GDSC2 11.8495 13.1383 10.4975 1.1787
BL-41 GDSC2 11.8753 13.4784 10.3621 1.8502
Ramos.2G6.4C10 GDSC2 11.9149 13.344 10.4435 1.3638
MHH-PREB-1 GDSC2 11.9381 13.5634 10.3599 1.766
697 GDSC2 11.955 13.6237 10.3426 1.8325
NCI-H929 GDSC2 11.9764 14.0747 10.151 2.8551
RPMI-8866 GDSC2 11.983 14.0105 10.1845 2.6549
L-428 GDSC2 11.9863 14.3515 10.029 3.5372
CTV-1 GDSC2 11.9926 20.7428 6.9045 20.4271
WSU-NHL GDSC2 11.9982 15.8927 9.3007 7.8569
Ku812 GDSC2 12.0065 19.4972 7.5333 17.5593
SR GDSC2 12.0765 14.1239 10.1882 2.4793
Karpas-45 GDSC2 12.1014 16.4166 9.119 8.7061
YT GDSC2 12.1207 13.4785 10.4915 0.8898
SUP-T1 GDSC2 12.1414 18.7491 8.0051 14.8589
P12-Ichikawa GDSC2 12.1598 21.1118 6.8502 20.2252
RC-K8 GDSC2 12.1658 13.6321 10.4501 1.0261
DEL GDSC2 12.1757 13.1628 10.6395 0.2951
KE-37 GDSC2 12.1817 13.6222 10.4619 0.9567
KY821 GDSC2 12.1837 13.706 10.4283 1.1058
Namalwa GDSC2 12.187 18.6836 8.0714 14.3995
Karpas-620 GDSC2 12.1942 13.6054 10.4748 0.888
CCRF-CEM GDSC2 12.2074 14.3056 10.1819 2.3089
Karpas-299 GDSC2 12.2474 14.073 10.3055 1.6157
SK-MM-2 GDSC2 12.2525 15.8089 9.5143 6.0375
GR-ST GDSC2 12.2568 15.5641 9.6329 5.3322
HL-60 GDSC2 12.2637 20.9703 6.9997 19.3284
MV4-11 GDSC2 12.2747 14.9862 9.9134 3.6803
KMOE-2 GDSC2 12.288 26.8512 4.0963 28.6695
Daudi GDSC2 12.2897 13.512 10.5551 0.4941
OCI-AML-2 GDSC2 12.2915 13.4076 10.5954 0.3617
KCL-22 GDSC2 12.3097 14.0923 10.3295 1.4217
JVM-3 GDSC2 12.3118 14.2188 10.2768 1.6749
TK [Human B-cell lymphoma] GDSC2 12.3337 14.8074 10.0297 2.9349
Karpas-422 GDSC2 12.3489 13.6612 10.523 0.5641
MHH-CALL-2 GDSC2 12.3635 13.9729 10.4057 1.0167
ALL-PO GDSC2 12.3668 14.6409 10.1226 2.3863
Loucy GDSC2 12.3676 13.9512 10.4165 0.9665
SUP-B15 GDSC2 12.4028 14.1753 10.3414 1.2601
NOMO-1 GDSC2 12.4047 13.6122 10.5652 0.3882
Granta-519 GDSC2 12.4103 14.2552 10.3118 1.3874
BE-13 GDSC2 12.4225 23.7348 5.751 23.683
SUP-M2 GDSC2 12.4342 13.563 10.5951 0.2876
ME1 GDSC2 12.4446 13.6698 10.5599 0.3814
EoL-1 GDSC2 12.4454 14.5056 10.2237 1.7656
JVM-2 GDSC2 12.4648 14.663 10.1663 2.025
MOLT-4 GDSC2 12.4834 14.1341 10.3968 0.939
LAMA-84 GDSC2 12.484 14.5625 10.2196 1.7378
AMO1 GDSC2 12.4863 13.9189 10.4829 0.6063
Jiyoye GDSC2 12.4867 15.2562 9.9164 3.3092
SCC-3 GDSC2 12.4944 13.5631 10.6183 0.2063
CTB-1 GDSC2 12.5057 22.3435 6.5038 20.7634
K-562 GDSC2 12.5583 14.1574 10.4216 0.7761
Karpas-231 GDSC2 12.5603 13.9665 10.4962 0.5108
HH [Human lymphoma] GDSC2 12.5837 16.142 9.5696 5.0825
JURL-MK1 GDSC2 12.5855 14.556 10.2734 1.3688
RPMI-6666 GDSC2 12.6106 14.0244 10.4953 0.4826
Raji GDSC2 12.6351 14.0228 10.5059 0.4356
P31/FUJ GDSC2 12.6484 32.5623 1.5358 32.7798
ML-2 GDSC2 12.6546 14.3921 10.3723 0.8864
KG-1 GDSC2 12.6615 14.6473 10.2727 1.2924
RS4;11 GDSC2 12.6641 23.2215 6.1893 21.5712
HDLM-2 GDSC2 12.689 17.4325 9.0312 7.9553
BALL-1 GDSC2 12.6973 14.4402 10.3724 0.8503
Reh GDSC2 12.7199 14.1705 10.4854 0.4493
RPMI-8226 GDSC2 12.7202 14.6014 10.3189 1.0412
MOLP-8 GDSC2 12.7454 13.951 10.5749 0.2108
Jurkat GDSC2 12.7477 14.1304 10.5113 0.3615
Karpas-1106P GDSC2 12.7648 15.1219 10.1264 1.8447
EB2 GDSC2 12.7719 14.1718 10.5057 0.3649
P32/ISH GDSC2 12.8229 14.0452 10.5704 0.1947
RPMI-8402 GDSC2 12.8281 14.2871 10.4857 0.3917
HC-1 GDSC2 12.8558 14.2999 10.4919 0.3618
NALM-6 GDSC2 12.8679 14.6115 10.3804 0.6936
LC4-1 GDSC2 12.8731 14.7244 10.3391 0.8363
ALL-SIL GDSC2 12.8754 14.4913 10.4291 0.5305
EM-2 GDSC2 12.8836 14.2594 10.5173 0.2871
ARH-77 GDSC2 12.8858 14.381 10.4741 0.3948
A4/Fukuda GDSC2 12.8864 14.3443 10.4877 0.3586
VL51 GDSC2 12.9016 14.6719 10.3717 0.7004
Hs 445 GDSC2 12.9075 14.2084 10.5443 0.2196
ST486 GDSC2 12.9122 14.5108 10.4368 0.4864
ATN-1 GDSC2 12.9191 14.2084 10.5487 0.2073
SU-DHL-6 GDSC2 12.9428 14.5903 10.4197 0.5203
MOLM-13 GDSC2 12.9709 14.6665 10.4027 0.5558
JSC-1 GDSC2 12.9768 15.2284 10.1859 1.3519
HAL-01 GDSC2 12.9791 14.7128 10.3887 0.5944
H9 GDSC2 12.981 14.4762 10.4767 0.3446
PF-382 GDSC2 12.9964 15.074 10.2567 1.0479
KMS-12-BM GDSC2 13.01 14.5183 10.4727 0.3421
JJN-3 GDSC2 13.0196 14.3395 10.5396 0.1942
CESS GDSC2 13.0243 14.9068 10.334 0.7447
OCI-AML-5 GDSC2 13.0336 24.5922 5.7897 22.1242
BV-173 GDSC2 13.0357 14.7009 10.4162 0.4798
DG-75 GDSC2 13.0363 14.7555 10.3962 0.538
CA46 GDSC2 13.0744 14.761 10.4095 0.4787
L-1236 GDSC2 13.0786 15.6006 10.0826 1.6962
OPM-2 GDSC2 13.0957 14.4113 10.5423 0.169
U266B1 GDSC2 13.1223 24.7844 5.761 22.022
TUR GDSC2 13.1971 14.4903 10.5512 0.1319
L-540 GDSC2 13.2044 14.8606 10.4242 0.3786
MLMA GDSC2 13.2769 14.8726 10.4475 0.2962
Mono-Mac-6 GDSC2 13.2998 22.2729 7.1195 16.3777
MN-60 GDSC2 13.3163 15.4145 10.264 0.7845
SUP-HD1 GDSC2 13.3716 15.4009 10.2921 0.6609
DND-41 GDSC2 13.3745 15.0707 10.4138 0.3346
MEG-01 GDSC2 13.3805 15.3378 10.3192 0.5754
SU-DHL-8 GDSC2 13.6847 26.7188 5.2243 22.5368
⏷ Show the Full List of 130 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SN12C GDSC2 11.8783 15.3404 9.4844 7.0196
A-498 GDSC2 12.0207 20.0723 7.2591 18.8012
BFTC-909 GDSC2 12.051 14.2995 10.093 3.0535
SW13 GDSC2 12.15 20.5841 7.1044 19.1606
A-704 GDSC2 12.2101 14.7138 9.9992 3.3078
LB996-RCC GDSC2 12.4396 19.4191 7.8956 14.6923
TK-10 GDSC2 12.4698 17.0646 9.0604 8.2413
KTCTL-195 GDSC2 12.5156 19.7305 7.7983 14.9995
769-P GDSC2 12.5297 14.9463 10.0782 2.385
786-O GDSC2 12.5864 17.2564 9.047 8.0748
CAL-54 GDSC2 12.7255 18.9615 8.3225 11.8052
VMRC-RCZ GDSC2 12.8341 15.9359 9.8109 3.3404
ACHN GDSC2 13.0546 14.5359 10.4834 0.2986
OS-RC-2 GDSC2 13.2927 22.8832 6.8174 17.6781
KMRC-20 GDSC2 13.579 22.4471 7.2301 15.292
KMRC-1 GDSC2 13.8062 25.3145 5.9987 19.7172
RCC10RGB GDSC2 13.9535 25.2715 6.124 18.9616
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO205 GDSC2 11.1761 19.4022 6.9216 22.5991
C2BBe1 GDSC2 11.5227 17.5128 8.144 15.7404
LS180 GDSC2 11.582 18.2702 7.8136 17.3067
CaR-1 GDSC2 11.6231 17.4032 8.2771 14.744
SW948 GDSC2 11.6261 16.9483 8.5055 13.4596
LoVo GDSC2 11.7038 17.5214 8.2809 14.5083
HT-55 GDSC2 11.7143 13.6439 10.1873 3.1301
LS1034 GDSC2 11.8483 13.8096 10.1947 2.8337
GP5d GDSC2 11.8875 21.2166 6.5868 21.9987
SNU-407 GDSC2 11.9688 19.025 7.7385 16.6548
RKO GDSC2 11.9729 14.5703 9.9178 4.2137
SK-CO-1 GDSC2 12.0141 14.4528 9.9993 3.6579
NCI-H747 GDSC2 12.0215 19.391 7.5974 17.2119
SW1417 GDSC2 12.1144 17.9218 8.3924 12.8497
HT-29 GDSC2 12.126 19.1718 7.785 16.0206
RCM-1 [Human ESC] GDSC2 12.1329 17.8526 8.44 12.5417
SW48 GDSC2 12.1467 14.9661 9.8432 4.3159
LS123 GDSC2 12.1833 16.0497 9.353 7.1367
SNU-61 GDSC2 12.2052 14.2905 10.1874 2.2831
CW-2 GDSC2 12.2259 14.8501 9.9463 3.5796
HCT 116 GDSC2 12.2286 18.6746 8.1065 14.1126
SW837 GDSC2 12.241 19.5998 7.66 16.3509
SW626 GDSC2 12.3298 16.2214 9.3694 6.7322
NCI-H716 GDSC2 12.3667 22.8066 6.1685 22.3653
COLO 320HSR GDSC2 12.3878 18.181 8.4637 11.8052
CCK-81 GDSC2 12.3906 14.7595 10.0835 2.5576
COLO 678 GDSC2 12.4598 17.0488 9.0612 8.2577
SW1463 GDSC2 12.4902 18.9178 8.1775 13.1124
SW1116 GDSC2 12.492 14.862 10.0945 2.3537
LS411N GDSC2 12.5411 22.6749 6.3666 21.2047
SNU-175 GDSC2 12.6655 19.6934 7.9246 14.0142
T84 GDSC2 12.7658 18.1765 8.7278 9.5047
KM12 GDSC2 12.8198 20.9095 7.4416 16.0043
CL-11 GDSC2 12.8785 22.0365 6.9323 18.1335
HCC2998 GDSC2 12.9244 17.3903 9.2021 6.5338
SNU-C5 GDSC2 13.0109 16.396 9.7061 3.63
SNU-C1 GDSC2 13.0317 14.8182 10.3708 0.6189
DiFi GDSC2 13.2693 23.0742 6.7074 18.18
LS513 GDSC2 13.48 26.6553 5.105 23.3308
HCT 15 GDSC2 13.5534 23.1744 6.8604 16.9336
SNU-C2B GDSC2 13.8336 17.002 9.8708 1.8544
MDST8 GDSC2 14.785 29.5268 4.6434 22.0775
SW620 GDSC2 15.126 26.9827 6.1027 16.7739
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 12.2318 14.1592 10.2599 1.8662
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-6 GDSC2 11.2665 14.0644 9.6594 7.4336
JHH-2 GDSC2 11.874 16.9002 8.7173 11.6066
SNU-398 GDSC2 12.1597 23.7311 5.5488 24.9831
HuH-1 GDSC2 12.1809 17.207 8.7907 10.4425
HLE GDSC2 12.2884 15.6635 9.6065 5.4248
SNU-449 GDSC2 12.3548 16.4829 9.2613 7.3141
Hep-G2/C3A GDSC2 12.3744 23.0006 6.0782 22.6714
JHH-4 GDSC2 12.6474 20.855 7.343 16.8638
SNU-387 GDSC2 12.7958 18.5127 8.587 10.2192
Huh-7 GDSC2 12.9919 23.9375 6.0813 21.1997
SNU-423 GDSC2 13.0665 17.2933 9.334 5.549
JHH-7 GDSC2 13.1522 22.6742 6.8186 17.9853
JHH-1 GDSC2 13.4674 28.3588 4.2559 25.7118
SK-HEP-1 GDSC2 16.282 31.0669 4.9256 18.6349
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 126 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DMS 273 GDSC2 11.0107 23.8316 4.5702 30.677
SBC-3 GDSC2 11.24 15.8104 8.768 12.9865
LXF 289 GDSC2 11.3249 14.1529 9.6607 7.2717
LCLC-103H GDSC2 11.353 14.1719 9.6729 7.1226
NCI-H1092 GDSC2 11.4421 14.1388 9.7567 6.3746
Ms-1 GDSC2 11.4597 13.888 9.8931 5.4828
COR-L95 GDSC2 11.501 15.8528 8.9527 11.1735
NCI-H847 GDSC2 11.5436 13.4545 10.1638 3.6232
NCI-H1435 GDSC2 11.5584 18.848 7.507 18.8825
NCI-H82 GDSC2 11.5784 14.4381 9.7099 6.3336
SW1271 GDSC2 11.6772 13.8856 10.0478 4.04
NCI-H1648 GDSC2 11.6895 19.1501 7.46 18.7475
NCI-H2066 GDSC2 11.6982 13.8714 10.0687 3.8697
NCI-H526 GDSC2 11.7351 13.8552 10.1009 3.6014
COR-L311 GDSC2 11.751 13.7732 10.1501 3.278
LC-1/sq GDSC2 11.7798 19.5654 7.3241 19.1385
NCI-H1155 GDSC2 11.7888 21.2541 6.4904 22.6354
A-549 GDSC2 11.8974 14.194 10.0463 3.6043
NCI-H1573 GDSC2 11.8986 19.7678 7.316 18.8603
SK-MES-1 GDSC2 11.9021 17.7834 8.3024 13.8756
DMS 114 GDSC2 11.9201 14.9482 9.7028 5.6059
NCI-H196 GDSC2 11.9305 14.7104 9.8236 4.859
NCI-H1693 GDSC2 11.9345 15.0693 9.6545 5.8661
NCI-H1975 GDSC2 12.0049 21.1232 6.7249 21.1393
NCI-H64 GDSC2 12.0262 22.9306 5.8425 24.3562
NCI-H1341 GDSC2 12.0313 17.6142 8.4824 12.5541
COLO 668 GDSC2 12.0524 17.598 8.5059 12.3704
NCI-H524 GDSC2 12.0602 14.2551 10.1189 2.8914
NCI-H1963 GDSC2 12.0847 22.0055 6.3485 22.406
NCI-H358 GDSC2 12.116 16.1425 9.262 7.8238
COR-L23 GDSC2 12.1307 15.7921 9.4409 6.7263
VMRC-LCD GDSC2 12.133 18.4483 8.1472 14.1325
NCI-H322M GDSC2 12.1454 16.335 9.1893 8.1905
NCI-H596 GDSC2 12.1488 17.3503 8.6977 11.0515
PC-14 GDSC2 12.1507 14.5546 10.0363 3.2011
NCI-H1781 GDSC2 12.2115 14.1909 10.2349 2.0234
NCI-H727 GDSC2 12.2269 17.8263 8.5213 11.8627
NCI-H2141 GDSC2 12.2348 14.5528 10.087 2.7798
HARA [Human squamous cell lung carcinoma] GDSC2 12.2616 14.4914 10.1299 2.5053
NCI-H2347 GDSC2 12.2862 17.594 8.6772 10.8463
NCI-H2373 GDSC2 12.2931 20.8678 7.0728 18.9382
NCI-H1651 GDSC2 12.298 14.6309 10.0883 2.6726
SK-LU-1 GDSC2 12.3211 17.6799 8.6602 10.862
NCI-H2228 GDSC2 12.3389 15.8731 9.5404 5.7121
HCC827 GDSC2 12.3481 15.8341 9.5647 5.5527
IA-LM GDSC2 12.3549 19.8173 7.6376 16.1787
NCI-H2087 GDSC2 12.3615 17.3521 8.8477 9.7025
NCI-H1993 GDSC2 12.3903 14.4487 10.2193 1.8584
LK-2 GDSC2 12.394 15.0797 9.9419 3.3192
NCI-H2795 GDSC2 12.4551 21.2405 7.0106 18.8071
NCI-H1299 GDSC2 12.4564 14.6211 10.18 1.9679
NCI-H650 GDSC2 12.4653 23.6404 5.8307 23.3116
NCI-H1792 GDSC2 12.4732 16.2502 9.4494 5.9791
NCI-H1793 GDSC2 12.4881 14.4969 10.2495 1.5895
SW1573 GDSC2 12.4988 23.1676 6.0906 22.3242
NCI-H810 GDSC2 12.505 20.5613 7.3826 17.0226
Lu-135 GDSC2 12.5228 21.5735 6.897 19.127
COR-L279 GDSC2 12.5299 13.8845 10.5146 0.4709
NCI-H1563 GDSC2 12.5469 15.8245 9.6935 4.4467
Calu-3 GDSC2 12.5572 21.7401 6.8405 19.2802
NCI-H1581 GDSC2 12.5693 14.1172 10.4422 0.691
NCI-H3122 GDSC2 12.581 17.6021 8.8781 9.0504
NCI-H1876 GDSC2 12.585 21.1465 7.1538 17.8662
NCI-H2369 GDSC2 12.5878 13.9553 10.5118 0.4449
NCI-H1944 GDSC2 12.5992 21.117 7.1788 17.721
NCI-H2818 GDSC2 12.6064 20.6848 7.3965 16.7149
NCI-H1755 GDSC2 12.622 14.3924 10.3573 0.9741
NCI-H1694 GDSC2 12.6291 13.9924 10.5148 0.4126
LOU-NH91 GDSC2 12.631 19.1174 8.1806 12.7709
PaCa-3 GDSC2 12.6544 15.5459 9.8828 3.2287
NCI-H2342 GDSC2 12.6554 22.7442 6.4185 20.7328
NCI-H2591 GDSC2 12.6593 16.0928 9.6384 4.561
Lu-139 GDSC2 12.6618 14.7397 10.2347 1.4607
Calu-6 GDSC2 12.6778 18.8253 8.3552 11.7363
NCI-H1688 GDSC2 12.6844 20.4167 7.5849 15.6432
HCC15 GDSC2 12.6894 19.9675 7.808 14.5435
NCI-H513 GDSC2 12.6906 20.5511 7.5235 15.921
EKVX GDSC2 12.6957 17.9293 8.7988 9.2553
NCI-H1666 GDSC2 12.7125 20.3612 7.6323 15.35
DMS 53 GDSC2 12.7143 22.3656 6.6493 19.6865
NCI-H2722 GDSC2 12.7206 20.4831 7.5785 15.589
NCI-H23 GDSC2 12.7254 14.6457 10.3035 1.0994
NCI-H522 GDSC2 12.7307 16.5416 9.4754 5.3505
NCI-H2023 GDSC2 12.7445 15.9947 9.7334 3.8946
HOP-62 GDSC2 12.7523 20.4925 7.5968 15.428
NCI-H2085 GDSC2 12.7535 16.224 9.6349 4.4205
NCI-H1650 GDSC2 12.7833 15.05 10.1658 1.6404
KNS-62 GDSC2 12.815 14.1861 10.5173 0.3153
NCI-H2595 GDSC2 12.8161 18.6214 8.5486 10.3862
NCI-H1703 GDSC2 12.819 17.3464 9.156 6.991
NCI-H1915 GDSC2 12.8285 14.8313 10.2768 1.1144
NCI-H2731 GDSC2 12.8525 15.0404 10.2034 1.3998
HCC78 GDSC2 12.856 14.5428 10.4016 0.6302
NCI-H1623 GDSC2 12.8592 24.3945 5.7567 22.6339
LCLC-97TM1 GDSC2 12.8816 15.0174 10.2265 1.2724
NCI-H226 GDSC2 12.8953 21.8044 7.0583 17.5538
NCI-H209 GDSC2 12.9033 15.1204 10.195 1.3851
NCI-H2009 GDSC2 12.9038 15.4886 10.0423 2.0783
NCI-H2122 GDSC2 12.9347 18.8704 8.5095 10.3481
NCI-H1568 GDSC2 12.9358 18.3885 8.7399 9.087
Lu-165 GDSC2 12.9442 14.2199 10.5538 0.1899
CPC-N GDSC2 12.9444 14.6503 10.3978 0.5867
COR-L88 GDSC2 12.9508 14.431 10.4814 0.346
Lu-65 GDSC2 12.9552 14.5837 10.4272 0.4911
Lu-99A GDSC2 12.9572 15.0761 10.2381 1.1554
UMC-11 GDSC2 13.0105 22.9234 6.5936 19.2194
NCI-H1838 GDSC2 13.0218 23.0962 6.5171 19.4954
COR-L105 GDSC2 13.0391 16.4018 9.7193 3.5194
SHP-77 GDSC2 13.1299 14.3376 10.5795 0.1065
NCI-H661 GDSC2 13.1348 22.8013 6.7439 18.3322
SBC-5 GDSC2 13.1641 26.0837 5.1516 23.8731
NCI-H441 GDSC2 13.1786 21.1387 7.5846 14.5268
NCI-H2170 GDSC2 13.2031 20.1437 8.0809 12.0348
NCI-H446 GDSC2 13.2812 23.2054 6.6519 18.3779
NCI-H520 GDSC2 13.2887 25.3173 5.6219 22.1177
NCI-H2405 GDSC2 13.3074 26.7701 4.9201 24.2438
NCI-H1355 GDSC2 13.3343 15.3783 10.2852 0.7045
RERF-LC-Sq1 GDSC2 13.3391 16.4017 9.8781 2.339
HOP-92 GDSC2 13.3583 21.2522 7.6541 13.8097
NCI-H69 GDSC2 13.3652 15.0805 10.4068 0.3543
EPLC-272H GDSC2 13.3741 15.8048 10.138 1.1922
EBC-1 GDSC2 13.463 22.4185 7.1634 15.8322
NCI-H2461 GDSC2 13.4982 20.6929 8.0163 11.7526
EMC-BAC-2 GDSC2 13.5999 23.3565 6.8047 17.0651
NCI-H1048 GDSC2 13.7124 27.873 4.6777 24.0801
RERF-LC-KJ GDSC2 14.4534 28.4939 4.9108 21.9364
⏷ Show the Full List of 126 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 12.8257 14.7679 10.3008 1.0207
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EC-GI-10 GDSC2 12.1014 21.519 6.6031 21.3804
OE19 GDSC2 12.1309 16.4 9.1478 8.4688
COLO 680N GDSC2 12.155 14.3549 10.1297 2.6736
TE-1 GDSC2 12.1893 17.5696 8.6197 11.399
OE33 GDSC2 12.2344 15.467 9.6643 5.1924
TE-9 GDSC2 12.2369 14.2272 10.2329 1.9977
TE-4 GDSC2 12.2525 17.0625 8.9118 9.5781
TE-10 GDSC2 12.2561 24.1847 5.3985 25.2176
TE-5 GDSC2 12.3465 19.4543 7.81 15.3485
TE-6 GDSC2 12.3651 14.3751 10.2377 1.7997
KYSE-270 GDSC2 12.4387 16.4475 9.3338 6.7184
OE21 GDSC2 12.4682 19.6551 7.8008 15.1007
KYSE-450 GDSC2 12.5574 20.0696 7.6626 15.5682
T.T GDSC2 12.6069 18.5775 8.4257 11.5136
TE-15 GDSC2 12.685 19.6215 7.9736 13.7199
KYSE-70 GDSC2 12.9357 15.1443 10.2006 1.3296
KYSE-410 GDSC2 13.022 22.3414 6.8873 17.9935
KYSE-520 GDSC2 13.0428 18.839 8.5965 9.6541
TE-8 GDSC2 13.2113 22.2205 7.0823 16.7348
KYSE-140 GDSC2 13.5305 16.1056 10.0895 1.2492
KYSE-180 GDSC2 13.635 22.2197 7.378 14.5125
KYSE-150 GDSC2 14.4728 24.4272 6.8856 14.9736
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2780 GDSC2 11.721 14.2726 9.8916 4.8929
Caov-3 GDSC2 11.9852 19.9289 7.3029 18.6938
DOV13 GDSC2 12.0116 18.334 8.1128 14.6192
TOV-21G GDSC2 12.0569 13.3131 10.5286 0.7934
OAW42 GDSC2 12.1007 18.4214 8.1364 14.2702
TYK-nu GDSC2 12.1661 15.8893 9.4182 6.7858
TOV-112D GDSC2 12.3707 17.1292 8.9618 9.025
OVCAR-3 GDSC2 12.3791 18.0846 8.5044 11.6
OVCAR-5 GDSC2 12.3887 14.5314 10.1826 2.0453
OC 314 GDSC2 12.4224 14.3401 10.2822 1.5122
Caov-4 GDSC2 12.4281 14.7753 10.0974 2.4293
RMG-I GDSC2 12.4514 21.3891 6.9345 19.142
Kuramochi GDSC2 12.6248 16.3889 9.4805 5.5139
OVKATE GDSC2 12.8967 20.839 7.5312 15.4077
OVCAR-4 GDSC2 12.9056 15.0065 10.2421 1.1854
IGROV-1 GDSC2 12.932 14.6699 10.3853 0.6347
OVCAR-8 GDSC2 13.1651 26.2797 5.0555 24.1573
OVTOKO GDSC2 13.1823 22.9649 6.6982 18.411
OV56 GDSC2 13.2291 21.6573 7.3686 15.4204
OAW28 GDSC2 13.3174 17.8237 9.2418 5.6277
OV-90 GDSC2 14.1361 23.1949 7.2487 14.0803
EFO-21 GDSC2 14.1747 32.4159 2.7834 27.6861
OVISE GDSC2 14.3057 24.6716 6.6568 16.2232
ES-2 GDSC2 14.3957 29.8466 4.2089 23.9897
SK-OV-3 GDSC2 14.817 31.2421 3.8305 24.1622
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1990 GDSC2 11.7705 24.3009 4.9564 27.7092
SUIT-2 GDSC2 11.8187 14.5423 9.8287 5.0629
Capan-1 GDSC2 11.9686 14.3493 10.0189 3.6296
DAN-G GDSC2 12.1972 14.697 9.9991 3.3305
KP-4 GDSC2 12.2225 19.5008 7.695 16.2254
PaTu 8988t GDSC2 12.3943 14.3368 10.2693 1.608
BxPC-3 GDSC2 12.4226 15.1557 9.9243 3.3693
SU.86.86 GDSC2 12.4264 13.7063 10.5387 0.458
PL4 GDSC2 12.4378 14.6684 10.1495 2.1466
HuP-T3 GDSC2 12.4657 22.0863 6.6007 20.4794
PaTu 8902 GDSC2 12.504 13.767 10.5479 0.3839
PSN1 GDSC2 12.5281 14.7161 10.1769 1.8905
Panc 04.03 GDSC2 12.539 15.1055 10.0134 2.7087
KP-3 GDSC2 12.7377 16.2196 9.6275 4.4881
HPAC GDSC2 12.8856 20.5411 7.6684 14.7778
AsPC-1 GDSC2 12.9628 19.2524 8.3455 11.1676
Panc 02.03 GDSC2 13.0031 20.5206 7.7613 14.0624
Panc 08.13 GDSC2 13.0674 23.6036 6.3013 20.2193
KP-2 GDSC2 13.0888 19.369 8.3746 10.7488
MIA PaCa-2 GDSC2 13.159 21.7207 7.2884 15.9388
HuP-T4 GDSC2 13.1762 21.7608 7.281 15.9336
Panc 03.27 GDSC2 13.2717 26.0921 5.2278 23.4069
KP-1N GDSC2 13.3706 15.7014 10.1769 1.0494
Capan-2 GDSC2 13.6265 23.1799 6.9089 16.5762
Panc 10.05 GDSC2 13.9443 24.0513 6.7082 16.7406
CFPAC-1 GDSC2 14.2372 25.3357 6.2907 17.7724
Hs 766T GDSC2 14.2904 28.9659 4.5636 23.2421
YAPC GDSC2 14.9559 26.5221 6.2089 16.6988
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 GDSC2 12.0934 16.267 9.186 8.3267
MPP 89 GDSC2 12.4059 13.9282 10.4435 0.8197
IST-Mes1 GDSC2 12.5022 17.2972 8.9709 8.6878
MSTO-211H GDSC2 12.6974 14.916 10.1789 1.6769
NCI-H28 GDSC2 12.6995 21.0144 7.3029 16.9238
NCI-H2052 GDSC2 14.188 27.1786 5.3626 21.0763
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2 12.2078 27.275 3.8217 29.4845
PC-3 GDSC2 12.3837 25.9285 4.6308 27.1096
22Rv1 GDSC2 12.4883 18.2555 8.4986 11.3818
VCaP GDSC2 12.7298 23.4834 6.1094 21.7062
DU145 GDSC2 13.6799 21.4081 7.7965 12.4647
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 14.8291 30.1329 4.3799 22.7233
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
WM35 GDSC2 11.8753 13.7817 10.2242 2.6166
LOX-IMVI GDSC2 11.9441 14.5937 9.888 4.4471
COLO 792 GDSC2 11.9497 19.443 7.5167 17.7861
WM115 GDSC2 11.9526 15.0352 9.6831 5.655
UACC-257 GDSC2 12.042 16.4818 9.0451 9.2803
SK-MEL-1 GDSC2 12.0841 20.213 7.2379 18.7337
RPMI-7951 GDSC2 12.1805 14.8285 9.9285 3.7614
G-361 GDSC2 12.2011 20.6553 7.1081 19.0143
GAK GDSC2 12.2684 13.9566 10.3658 1.2991
COLO 829 GDSC2 12.3171 21.3603 6.8473 19.8412
SH-4 GDSC2 12.3768 15.3485 9.8089 4.093
IGR-37 GDSC2 12.3877 13.465 10.6126 0.2635
HT-144 GDSC2 12.4003 18.4011 8.3653 12.3148
COLO 679 GDSC2 12.4661 20.0004 7.6297 15.9466
HMV-II GDSC2 12.4783 16.8402 9.1733 7.5701
WM793 GDSC2 12.5385 16.802 9.2313 7.112
CHL-1 GDSC2 12.566 15.0956 10.0326 2.5691
UACC-62 GDSC2 12.5707 20.0664 7.6739 15.4815
WM1552C GDSC2 12.5883 21.0899 7.184 17.7239
A2058 GDSC2 12.7899 25.7177 5.0494 25.0116
IST-MEL1 GDSC2 12.8209 14.7856 10.2915 1.0616
A-375 GDSC2 12.9937 20.802 7.6181 14.7763
WM278 GDSC2 13.1076 22.7994 6.7251 18.4698
IGR-1 GDSC2 13.5479 25.9615 5.4958 21.9691
A101D GDSC2 13.5501 30.2949 3.3614 27.6609
WT2-iPS GDSC2 13.7744 23.6199 6.7989 16.7219
SK-MEL-24 GDSC2 13.9082 23.9926 6.7116 16.8011
RVH-421 GDSC2 14.2065 25.5068 6.1868 18.2187
MeWo GDSC2 14.3193 25.1634 6.43 17.082
Mel JuSo GDSC2 14.8743 28.5811 5.1644 20.3733
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-UT-1 GDSC2 11.6983 13.6337 10.1818 3.1944
SW982 GDSC2 11.7926 17.2716 8.4726 13.2108
EW-8 GDSC2 11.8816 14.4635 9.9087 4.4507
MFH-ino GDSC2 12.1417 17.7467 8.4984 12.1951
Hs 633.T GDSC2 12.2315 17.581 8.6445 11.159
RKN GDSC2 12.2433 23.6293 5.6646 24.4043
SW684 GDSC2 12.2615 13.2749 10.6324 0.2708
G-401 GDSC2 12.4008 14.9717 9.9946 3.0196
KYM-1 GDSC2 12.4575 14.1557 10.3759 1.0512
Rh30 GDSC2 12.5263 14.5327 10.2537 1.5251
G-402 GDSC2 12.5721 20.827 7.3014 17.234
GCT GDSC2 12.8138 21.7165 7.042 17.8139
VA-ES-BJ GDSC2 12.8753 22.3069 6.7972 18.7062
SK-LMS-1 GDSC2 12.8942 15.2204 10.1496 1.5929
Rh41 GDSC2 12.9308 19.5898 8.1612 12.204
SW872 GDSC2 13.1969 14.8679 10.4187 0.3955
HT-1080 GDSC2 13.3758 22.1028 7.2555 15.612
A-204 GDSC2 13.5242 24.6125 6.1393 19.809
MES-SA GDSC2 13.9311 24.2483 6.604 17.1844
RD GDSC2 14.4474 23.4337 7.3397 13.0854
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RF-48 GDSC2 11.7131 13.967 10.033 4.0535
HSC-39 GDSC2 11.7303 16.6104 8.7525 11.7647
Fu97 GDSC2 11.7316 13.8241 10.1134 3.534
GCIY GDSC2 12.1231 16.873 8.9123 9.8721
RERF-GC-1B GDSC2 12.1572 22.9714 5.9247 23.7466
MKN45 GDSC2 12.1726 20.277 7.2737 18.3453
HGC-27 GDSC2 12.3594 16.5982 9.2093 7.6091
SNU-5 GDSC2 12.3865 13.7907 10.4891 0.6592
SK-GT-2 GDSC2 12.448 15.031 9.9951 2.9431
TGBC11TKB GDSC2 12.4705 19.6909 7.7849 15.1741
SNU-16 GDSC2 12.5024 13.6269 10.5985 0.2489
KATO III GDSC2 12.6157 14.5527 10.2894 1.2662
OCUM-1 GDSC2 12.6686 15.3225 9.9894 2.6475
IM95 GDSC2 12.7567 23.8239 5.9614 22.169
Hs 746.T GDSC2 12.8155 17.8249 8.9281 8.2823
AGS GDSC2 12.9278 21.7355 7.1156 17.2292
ECC10 GDSC2 12.9383 24.1016 5.9605 21.7514
23132/87 GDSC2 13.0203 14.3074 10.551 0.1737
NCI-N87 GDSC2 13.0238 15.0254 10.288 0.9082
SNU-1 GDSC2 13.0602 14.4551 10.5141 0.2309
MKN28 GDSC2 13.1049 25.0828 5.601 22.5933
NUGC-4 GDSC2 13.2249 26.601 4.9418 24.3593
NUGC-3 GDSC2 13.7383 24.8319 6.1854 19.1842
SNG-M GDSC2 12.7371 15.0216 10.1546 1.7445
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TT2609-C02 GDSC2 11.766 20.3143 6.9405 20.8732
TT GDSC2 11.8097 14.9939 9.6044 6.4453
BHT-101 GDSC2 11.8265 14.8808 9.6709 6.0025
WRO GDSC2 11.8947 16.6823 8.8399 10.8416
CGTH-W-1 GDSC2 11.909 24.1821 5.1263 26.884
ASH-3 GDSC2 11.9147 16.8942 8.7504 11.3138
IHH-4 GDSC2 12.0572 18.7648 7.9343 15.4367
CAL-62 GDSC2 12.07 14.6325 9.9506 3.8362
FTC-133 GDSC2 12.2072 18.0872 8.3793 12.6966
HTC-C3 GDSC2 12.3504 22.1982 6.4577 21.3228
8305C GDSC2 12.353 14.363 10.2364 1.8216
B-CPAP GDSC2 12.4923 14.0434 10.437 0.7715
8505C GDSC2 12.799 18.9342 8.3865 11.3009
K5 GDSC2 13.0931 21.8417 7.1826 16.5584
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 22 GDSC2 11.7794 14.3677 9.8859 4.8013
HO-1-N-1 GDSC2 11.8079 17.3993 8.4211 13.4603
SAS GDSC2 11.9353 17.9829 8.2289 14.1912
SKN-3 GDSC2 12.0367 15 9.7562 5.0434
HSC-4 GDSC2 12.2227 22.2419 6.3379 22.0967
OSC-20 GDSC2 12.3438 17.6804 8.6761 10.7206
JHU-022 GDSC2 12.4061 16.3607 9.3536 6.6693
Ca9-22 GDSC2 12.4117 18.3579 8.3945 12.1292
SCC-4 GDSC2 12.4618 24.9397 5.1831 25.3769
SAT [Human HNSCC] GDSC2 12.6321 16.1093 9.6144 4.743
HSC-2 GDSC2 12.637 18.8147 8.3318 11.9535
PCI-30 GDSC2 12.6654 18.6866 8.4137 11.4482
BICR 78 GDSC2 12.6696 22.5303 6.5348 20.2476
SCC-15 GDSC2 12.756 22.1731 6.7751 19.0768
Detroit 562 GDSC2 12.8068 25.2547 5.2916 24.2483
HSC-3 GDSC2 12.9393 20.5833 7.686 14.5714
LB771-HNC GDSC2 12.9651 22.8887 6.5774 19.3882
SCC-9 GDSC2 12.9917 15.459 10.0986 1.7171
HO-1-u-1 GDSC2 13.0066 23.0121 6.5473 19.4117
DOK GDSC2 13.1236 22.144 7.057 17.04
NCI-H3118 GDSC2 13.1534 15.6076 10.1154 1.4789
UPCI-SCC-090 GDSC2 13.323 15.4237 10.2633 0.7823
CAL-33 GDSC2 13.5625 24.3324 6.3035 19.1184
CAL-27 GDSC2 14.0864 30.1821 3.818 25.5628
FaDu GDSC2 14.1939 22.6693 7.5361 12.6819
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC2 11.7707 17.3819 8.4014 13.6667
TCCSUP GDSC2 11.7745 21.5117 6.3507 23.2043
KU-19-19 GDSC2 12.0138 16.1596 9.182 8.5319
HT-1197 GDSC2 12.3976 20.7671 7.2013 18.1103
5637 GDSC2 12.4146 17.7049 8.714 10.3455
CAL-29 GDSC2 12.5447 17.7168 8.7983 9.5809
647V GDSC2 12.7044 23.3564 6.153 21.6082
UM-UC-3 GDSC2 12.7318 17.4293 9.0607 7.7015
RT-112 GDSC2 12.8541 19.3692 8.2147 12.0928
SW780 GDSC2 12.8581 24.7644 5.573 23.2434
SW1710 GDSC2 12.8803 14.8439 10.2954 0.9954
639V GDSC2 13.4131 26.1005 5.3285 22.7895
RT-4 GDSC2 13.4492 25.0208 5.8852 20.8758
J82 GDSC2 13.9422 29.8913 3.8545 25.7549
HT-1376 GDSC2 14.0506 24.64 6.4975 17.3584
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PA-1 GDSC2 11.0059 13.7993 9.5823 8.6385
C-33 A GDSC2 11.3158 14.0721 9.6938 7.0881
HT-3 GDSC2 11.5739 19.4583 7.215 20.1947
NCC-IT GDSC2 11.8236 14.5361 9.835 5.0142
DSH1 GDSC2 11.9528 15.2319 9.5888 6.2227
ME-180 GDSC2 11.9629 15.0422 9.6867 5.6113
PWR-1E GDSC2 12.0481 18.9783 7.8219 16.0329
DoTc2 4510 GDSC2 12.1386 15.0773 9.7859 4.6663
HEC-1 GDSC2 12.1626 13.7469 10.4005 1.2599
BPH-1 GDSC2 12.2532 17.0046 8.9404 9.4105
OVCA420 GDSC2 12.3107 21.0143 7.0136 19.1509
LB831-BLC GDSC2 12.3224 19.9951 7.5258 16.7966
CAL-39 GDSC2 12.3691 18.6434 8.2244 13.1477
SKN GDSC2 12.5383 16.3066 9.4645 5.7672
C-4-I GDSC2 12.5589 20.5783 7.414 16.7473
MS751 GDSC2 12.6168 19.6552 7.9084 14.2088
HEY GDSC2 12.6263 20.4518 7.5254 16.0634
Ca Ski GDSC2 12.631 19.5435 7.9731 13.8471
KGN GDSC2 12.6495 20.5974 7.471 16.2652
NEC8 GDSC2 12.7867 14.9448 10.2109 1.434
PEO1 GDSC2 12.9389 15.0695 10.2323 1.1952
OVMIU GDSC2 13.0024 18.5977 8.6845 9.2567
SW756 GDSC2 13.1684 22.3969 6.9657 17.3315
SiSo GDSC2 13.1733 17.5664 9.2733 5.699
SKG-IIIa GDSC2 13.248 25.0553 5.7207 21.8784
SiHa GDSC2 13.314 25.2966 5.6507 21.9669
HeLa GDSC2 13.409 22.7999 6.9405 16.9085
NT2-D1 GDSC2 13.4731 24.3474 6.232 19.5783
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug

References

1 FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 074037.
2 ClinicalTrials.gov (NCT04279197) Treatment of Pulmonary Fibrosis Due to 2019-nCoV Pneumonia With Fuzheng Huayu. U.S. National Institutes of Health.