Details of the Drug

General Information of Drug (ID: DMC4UHD)

Drug Name
PF-543
Synonyms sphingosine kinase 1 Inhibitor II; PF 543
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 465.6
Logarithm of the Partition Coefficient (xlogp) 4.2
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C27H31NO4S
IUPAC Name
[(2R)-1-[[4-[[3-(benzenesulfonylmethyl)-5-methylphenoxy]methyl]phenyl]methyl]pyrrolidin-2-yl]methanol
Canonical SMILES
CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCC[C@@H]3CO)CS(=O)(=O)C4=CC=CC=C4
InChI
InChI=1S/C27H31NO4S/c1-21-14-24(20-33(30,31)27-7-3-2-4-8-27)16-26(15-21)32-19-23-11-9-22(10-12-23)17-28-13-5-6-25(28)18-29/h2-4,7-12,14-16,25,29H,5-6,13,17-20H2,1H3/t25-/m1/s1
InChIKey
NPUXORBZRBIOMQ-RUZDIDTESA-N
Cross-matching ID
PubChem CID
66577038
ChEBI ID
CHEBI:131144
CAS Number
1415562-82-1
TTD ID
D08SND

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Sphingosine kinase 1 (SPHK1) TTOHFIY SPHK1_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Sphingosine kinase 1 (SPHK1) DTT SPHK1 7.48E-01 -0.01 -0.06
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.5316 5.7014 0.6186 1.293
EW-24 GDSC1 2.704 3.9515 0.9368 0.6319
CHSA8926 GDSC1 2.9327 5.0294 0.6074 2.091
CAL-72 GDSC1 2.9576 6.5207 -0.0449 6.364
TC-71 GDSC1 3.0089 4.8246 0.7293 1.3108
NOS-1 [Human HNSCC] GDSC1 3.0761 6.128 0.2054 4.4034
ES8 GDSC1 3.278 5.1493 0.7223 1.0601
ES6 GDSC1 3.48 6.0552 0.4518 2.2135
A-673 GDSC1; CTRP2 3.5433 4.7589 3.4743 10.2375
EW-7 GDSC1 3.5504 5.4933 0.707 0.8875
CADO-ES1 GDSC1 3.6089 5.2727 0.8122 0.4712
HuO-3N1 GDSC1 3.7021 6.7802 0.2596 2.9969
EW-13 GDSC1 3.8192 5.7049 0.7373 0.5915
ES4 GDSC1 3.9327 6.1247 0.6277 0.9081
EW-1 GDSC1 3.9547 6.1137 0.6408 0.8426
Hs 888.T CTRP2 3.9743 6.1583 3.4577 9.0711
SK-N-MC CTRP2 3.9862 5.6651 3.6761 8.1869
EW-16 GDSC1 4.0037 6.2437 0.6122 0.9154
ES1 GDSC1 4.0942 6.0078 0.7339 0.4595
MHH-ES-1 GDSC1; CTRP2 4.1379 5.6461 3.8442 7.1216
SK-PN-DW GDSC1 4.15 5.9224 0.7845 0.311
EW-18 GDSC1 4.2223 6.161 0.7276 0.4202
SK-ES-1 GDSC1; CTRP2 4.2258 5.5406 3.9796 6.3575
Hs 822.T CTRP2 4.2324 4.8449 4.2036 5.508
EW-22 GDSC1 4.2746 6.0888 0.7719 0.2967
EW-3 GDSC1 4.2785 6.2778 0.7073 0.4493
SW1353 CTRP2 4.2795 5.424 4.0822 5.8149
NY GDSC1 4.2996 6.7722 0.5357 0.9917
H-EMC-SS GDSC1 4.3099 6.5199 0.6327 0.6494
HuO9 GDSC1 4.3117 6.8257 0.5207 1.0404
MG-63 GDSC1; CTRP2 4.3478 5.1274 4.26 4.9515
TC71 CTRP2 4.537 5.0069 4.5004 3.5075
SJSA-1 GDSC1; CTRP2 4.6345 5.8426 4.2676 4.1534
ES7 GDSC1 4.6927 7.8585 0.288 1.6884
U2OS GDSC1; CTRP2 4.6931 6.079 4.2115 4.2436
G-292 clone A141B1 GDSC1; CTRP2 4.7233 5.7851 4.3813 3.4757
CAL-78 GDSC1; CTRP2 4.7523 6.8068 3.9093 5.3668
HOS GDSC1; CTRP2 4.7558 7.844 3.3974 7.5004
SaOS-2 GDSC1; CTRP2 5.0184 7.0555 4.0171 4.3685
ES5 GDSC1 5.3627 16.9052 -3.3863 18.777
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 213 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 2.5055 5.6308 2.0939 18.3829
MEC1 CTRP2 4.2052 5.6898 3.8972 6.7327
JM1 GDSC1; CTRP2 3.4776 5.4531 3.2077 11.4048
AMO1 GDSC1; CTRP2 1.944 3.796 1.9024 20.7957
Peer CTRP2 2.1578 3.742 2.1319 19.3179
MHH-CALL-4 CTRP2 2.1689 7.732 0.9127 23.716
NU-DUL-1 GDSC1; CTRP2 2.1775 3.4712 2.1686 19.1295
KOPN-8 GDSC1 2.3222 4.0168 0.7185 2.4233
SU-DHL-5 GDSC1 2.3706 3.5812 0.9322 1.014
GA-10 GDSC1 2.3947 4.6852 0.457 4.0926
Sc-1 GDSC1 2.4302 4.367 0.6236 2.8535
DoHH2 GDSC1 2.4536 8.4835 -1.3394 16.3755
EoL-1 GDSC1; CTRP2 2.5582 3.7974 2.5446 16.6088
Ku812 GDSC1; CTRP2 2.6389 5.4066 2.312 17.1847
BC-3 GDSC1 2.6739 4.821 0.5595 2.8185
Karpas-231 GDSC1 2.6871 4.5959 0.6649 2.1243
Hs 611.T CTRP2 2.7047 4.8428 2.5431 16.1479
RPMI-8402 GDSC1; CTRP2 2.7108 4.4435 2.6329 15.8126
JSC-1 GDSC1 2.7192 5.0462 0.4851 3.2253
ML-2 GDSC1 2.7307 4.7836 0.607 2.414
NCO2 CTRP2 2.7903 6.0197 2.263 16.9287
ME1 GDSC1 2.8588 3.9453 1.0017 0.2891
SU-DHL-8 GDSC1; CTRP2 2.8742 6.3574 2.2222 16.8483
Daudi GDSC1; CTRP2 2.8746 4.2989 2.8305 14.6048
NALM-6 GDSC1; CTRP2 2.915 4.8633 2.7673 14.6986
HC-1 GDSC1 2.9219 7.1685 -0.3716 8.7188
SCC-3 GDSC1 2.9301 4.0806 0.9804 0.3162
EB2 GDSC1 2.939 4.9221 0.6556 1.801
MOLT-4 GDSC1 2.955 5.3722 0.472 2.8869
BALL-1 GDSC1 2.9573 4.5359 0.8205 0.9183
JVM-3 GDSC1; CTRP2 3.0251 5.4558 2.716 14.5541
ARH-77 GDSC1 3.0839 4.7145 0.8064 0.8629
KMS-21-BM CTRP2 3.0897 5.0707 2.9039 13.6734
KHM-1B CTRP2 3.1024 5.1589 2.8928 13.6751
CML-T1 CTRP2 3.1394 4.6405 3.0601 12.9632
MHH-PREB-1 GDSC1 3.1427 5.2064 0.6376 1.6326
CTB-1 GDSC1 3.2135 6.039 0.3214 3.3968
ATN-1 GDSC1 3.2273 5.1103 0.7152 1.1435
LC4-1 GDSC1 3.239 5.2276 0.674 1.3311
BE-13 GDSC1 3.2796 5.1714 0.7145 1.0948
TUR GDSC1 3.2852 4.8478 0.84 0.5713
JURL-MK1 GDSC1; CTRP2 3.2899 5.6189 2.9469 12.9233
P32/ISH GDSC1 3.3235 4.7467 0.8918 0.3793
HH [Human lymphoma] GDSC1; CTRP2 3.3247 5.5965 2.9924 12.652
TALL-1 [Human adult T-ALL] CTRP2 3.3288 6.0821 2.8135 13.321
KM-H2 GDSC1; CTRP2 3.3526 6.0547 2.8496 13.1166
M-07e CTRP2 3.3532 5.912 2.9061 12.8983
YT GDSC1 3.3616 4.9572 0.8302 0.5562
KY821 GDSC1 3.3807 4.6717 0.9396 0.2305
A4/Fukuda GDSC1; CTRP2 3.4056 4.8437 3.3065 11.2607
Karpas-45 GDSC1 3.4214 5.1376 0.7875 0.6702
LP-1 GDSC1; CTRP2 3.4277 5.7225 3.0576 12.1122
Farage GDSC1 3.4307 4.9475 0.8607 0.4172
HuT 78 CTRP2 3.4381 7.3799 2.3669 14.7876
MN-60 GDSC1 3.4455 5.259 0.7518 0.7897
P12-Ichikawa GDSC1; CTRP2 3.4483 5.3164 3.2214 11.4395
L-1236 GDSC1 3.46 5.7208 0.5784 1.5647
SU-DHL-16 GDSC1 3.4639 4.8704 0.9007 0.2919
Jiyoye GDSC1 3.4953 7.6896 -0.2553 6.6166
RC-K8 GDSC1 3.5126 4.9884 0.8772 0.332
LAMA-84 GDSC1; CTRP2 3.525 5.8101 3.1286 11.568
CESS GDSC1 3.5398 5.1748 0.8208 0.4817
DND-41 GDSC1 3.5557 5.7069 0.6271 1.2299
WIL2 NS GDSC1 3.557 5.1588 0.8332 0.4347
MOLM-13 GDSC1; CTRP2 3.5589 5.4397 3.3003 10.8228
SU-DHL-1 GDSC1; CTRP2 3.5688 4.3912 3.5546 9.8785
Kasumi-1 CTRP2 3.5713 5.7411 3.2044 11.149
KE-37 GDSC1; CTRP2 3.5798 5.7036 3.2277 11.0366
MY-M12 GDSC1 3.5962 5.876 0.5787 1.4165
SK-MM-2 GDSC1 3.6088 5.8011 0.6137 1.2403
Loucy GDSC1 3.6091 5.192 0.8412 0.3864
VL51 GDSC1 3.612 5.6483 0.674 0.9733
Ki-JK CTRP2 3.6351 5.8324 3.2372 10.8452
Ramos.2G6.4C10 GDSC1 3.6529 5.061 0.9031 0.2194
Ri-1 CTRP2 3.6556 6.538 2.9643 11.8549
IM-9 GDSC1 3.6575 4.9416 0.9454 0.141
WSU-NHL GDSC1 3.682 5.5694 0.7326 0.6932
CTV-1 GDSC1 3.6937 5.3969 0.8 0.4638
KMS-34 CTRP2 3.7069 5.9762 3.2558 10.5759
PL21 CTRP2 3.7134 6.7997 2.9071 11.9327
P30/OHK GDSC1 3.7158 5.2653 0.855 0.3052
MOLP-8 GDSC1; CTRP2 3.7175 6.0493 3.2369 10.6207
MOLT-16 GDSC1; CTRP2 3.728 6.3578 3.1172 11.0616
TK [Human B-cell lymphoma] GDSC1 3.7435 5.359 0.8324 0.3506
F-36P CTRP2 3.7508 7.9222 2.4237 13.7868
KMS-11 GDSC1; CTRP2 3.7528 9.8036 1.5182 17.3934
697 GDSC1; CTRP2 3.7632 4.9957 3.6592 8.8977
PF-382 GDSC1; CTRP2 3.7672 6.5084 3.0917 11.0596
NK-92MI GDSC1 3.7707 5.1286 0.9216 0.1537
Hs 445 GDSC1 3.7811 5.3202 0.8597 0.2705
HAL-01 GDSC1 3.7848 5.5946 0.7639 0.526
U-698-M GDSC1 3.7882 5.4809 0.8059 0.4014
SU-DHL-6 GDSC1; CTRP2 3.7892 6.3593 3.1797 10.6541
U266B1 GDSC1; CTRP2 3.7985 6.03 3.3298 10.0403
KG-1 GDSC1 3.8009 6.0576 0.5978 1.1356
WSU-DLCL2 GDSC1; CTRP2 3.8043 4.8412 3.7406 8.4809
DG-75 GDSC1 3.8045 5.8307 0.6851 0.783
KMS-20 CTRP2 3.807 5.4948 3.5488 9.1756
K-562 GDSC1; CTRP2 3.8313 5.058 3.7168 8.4826
SU-DHL-10 GDSC1; CTRP2 3.87 5.4866 3.6197 8.7285
ALL-SIL GDSC1; CTRP2 3.8817 5.2838 3.7029 8.3831
KMS-26 CTRP2 3.9008 4.7633 3.8603 7.7573
EB1 CTRP2 3.9149 5.7614 3.5621 8.8226
OCI-Ly10 CTRP2 3.9158 7.248 2.9028 11.4454
VAL GDSC1 3.9159 5.9613 0.6816 0.721
RS4;11 GDSC1; CTRP2 3.9208 5.3456 3.7244 8.189
CCRF-CEM GDSC1 3.9231 5.3876 0.8871 0.1753
ROS-50 GDSC1 3.9286 6.2381 0.5831 1.0897
DB GDSC1; CTRP2 3.9368 5.2435 3.776 7.9508
Jurkat GDSC1; CTRP2 3.9472 5.5713 3.6708 8.3159
HDLM-2 GDSC1; CTRP2 3.9557 6.1019 3.463 9.0991
KCL-22 GDSC1; CTRP2 3.9799 6.042 3.5137 8.8356
KE-97 CTRP2 3.9803 5.3528 3.7863 7.7854
QIMR-WIL GDSC1 3.9844 6.045 0.6781 0.6903
Granta-519 GDSC1; CTRP2 3.9957 5.9339 3.5761 8.549
MEG-01 GDSC1 4.0208 5.7875 0.7843 0.3591
OCI-Ly19 GDSC1; CTRP2 4.0352 6.5359 3.3512 9.3392
BV-173 GDSC1; CTRP2 4.0575 6.3092 3.4761 8.7826
KMS-28BM CTRP2 4.058 6.088 3.5745 8.3906
OCI-AML-2 GDSC1; CTRP2 4.061 5.4261 3.8472 7.3248
OCI-Ly3 CTRP2 4.0629 6.3495 3.4635 8.8192
MOLT-13 GDSC1; CTRP2 4.0825 5.9386 3.6643 7.9719
Mino CTRP2 4.0888 5.5159 3.8434 7.2605
MLMA GDSC1 4.0954 5.9432 0.7572 0.3969
HuNS1 CTRP2 4.0956 5.6624 3.793 7.4351
NU-DHL-1 CTRP2 4.1226 5.2318 3.9816 6.6433
EHEB GDSC1; CTRP2 4.128 5.7893 3.775 7.4171
Mono-Mac-6 GDSC1 4.1318 7.4606 0.1894 2.7965
EM-2 GDSC1; CTRP2 4.135 5.5688 3.872 7.0223
KMS-12-BM GDSC1; CTRP2 4.1356 5.6102 3.8562 7.0812
ALL-PO GDSC1 4.1376 6.2909 0.6486 0.6966
RPMI-6666 GDSC1; CTRP2 4.1454 5.539 3.8948 6.9059
OCI-AML-3 GDSC1; CTRP2 4.1487 5.7089 3.83 7.1469
MOLT-3 CTRP2 4.1576 4.9817 4.0929 6.1328
RPMI-8226 GDSC1; CTRP2 4.1747 5.5954 3.9036 6.7911
ST486 GDSC1; CTRP2 4.1755 5.5385 3.9269 6.6992
A3/Kawakami GDSC1; CTRP2 4.1859 4.898 4.143 5.8671
SEM CTRP2 4.1937 5.1497 4.0852 6.0515
SU-DHL-4 GDSC1; CTRP2 4.2065 6.0354 3.7498 7.3094
Mono-Mac-1 CTRP2 4.2282 9.8272 1.9428 14.6385
L-428 GDSC1; CTRP2 4.2323 5.7425 3.9035 6.6354
OPM-2 GDSC1; CTRP2 4.2424 5.282 4.0944 5.8742
JJN-3 GDSC1; CTRP2 4.2438 5.2921 4.0924 5.8779
SET-2 CTRP2 4.2632 5.3292 4.1 5.7936
DEL GDSC1; CTRP2 4.2707 4.8356 4.2465 5.2369
HT GDSC1; CTRP2 4.2853 5.1622 4.181 5.4272
EJM GDSC1; CTRP2 4.2856 5.4438 4.081 5.8025
BC-1 GDSC1 4.2897 6.3987 0.6685 0.5516
Karpas-422 GDSC1; CTRP2 4.3157 5.0509 4.2473 5.0941
L-363 GDSC1; CTRP2 4.3299 5.378 4.1535 5.4017
SUP-HD1 GDSC1; CTRP2 4.3337 5.7957 3.9856 6.044
SUP-T1 GDSC1; CTRP2 4.337 5.6759 4.0406 5.8188
Karpas-299 GDSC1; CTRP2 4.3381 5.6411 4.0564 5.7541
CA46 GDSC1; CTRP2 4.3394 5.6491 4.0544 5.7586
MOLM-16 CTRP2 4.3473 6.7576 3.5549 7.7503
Namalwa CTRP2 4.3476 5.0242 4.2894 4.8454
L-540 GDSC1; CTRP2 4.3505 5.9594 3.9301 6.2214
MV4-11 GDSC1; CTRP2 4.3583 5.8329 3.9945 5.9451
AML-193 CTRP2 4.3969 4.9297 4.3655 4.4218
P31/FUJ GDSC1; CTRP2 4.4008 4.9608 4.3629 4.4186
HPB-ALL CTRP2 4.4051 9.4758 2.2757 12.9032
NCI-H929 CTRP2 4.4058 5.3528 4.2443 4.8422
H9 GDSC1 4.4067 5.9604 0.8613 0.1175
HD-MY-Z CTRP2 4.4186 5.0896 4.3486 4.4154
BL-70 CTRP2 4.419 4.9525 4.3846 4.2849
SKM-1 GDSC1; CTRP2 4.4259 5.0161 4.377 4.2908
GR-ST GDSC1 4.4414 6.8239 0.5735 0.7652
SUP-B15 GDSC1; CTRP2 4.443 5.2248 4.3313 4.4079
BDCM CTRP2 4.4494 5.391 4.2759 4.5998
RL GDSC1; CTRP2 4.4611 5.0166 4.4151 4.0461
RCH-ACV GDSC1; CTRP2 4.4642 5.8804 4.0807 5.3299
SUP-T11 CTRP2 4.477 5.7991 4.1304 5.0988
MM1.S CTRP2 4.4912 5.1266 4.4164 3.9509
KMOE-2 GDSC1 4.4919 6.0014 0.8764 0.089
JeKo-1 CTRP2 4.5082 5.3139 4.3686 4.081
SR GDSC1; CTRP2 4.509 5.1768 4.4192 3.8882
NOMO-1 GDSC1; CTRP2 4.5143 5.2797 4.3881 3.9897
RPMI-8866 GDSC1 4.5159 6.0621 0.8644 0.0981
TF-1 CTRP2 4.5167 5.3701 4.3556 4.1076
HEL 92.1.7 CTRP2 4.5175 10.1461 2.0422 13.6147
SIG-M5 GDSC1; CTRP2 4.5434 4.9522 4.5198 3.4188
JVM-2 GDSC1; CTRP2 4.5747 6.2533 4.0147 5.3292
KMS-18 CTRP2 4.5759 5.5822 4.3277 4.0586
SUP-M2 GDSC1; CTRP2 4.5809 5.0353 4.5411 3.2268
KO52 CTRP2 4.5935 4.9899 4.5661 3.0988
NB4 GDSC1; CTRP2 4.6108 5.6841 4.3174 4.0107
MC116 GDSC1; CTRP2 4.6122 5.3639 4.4589 3.4467
KMS-27 CTRP2 4.6136 7.1981 3.5903 6.9977
Ci-1 CTRP2 4.6193 4.9971 4.5925 2.925
GDM-1 GDSC1; CTRP2 4.6282 6.6166 3.8893 5.7231
OCI-AML-5 GDSC1; CTRP2 4.6369 5.0338 4.6026 2.8345
HL-60 GDSC1; CTRP2 4.645 5.4235 4.468 3.3231
NKM-1 GDSC1 4.6661 6.4636 0.782 0.1773
MOLM-6 CTRP2 4.6956 7.3215 3.6035 6.7653
U-937 CTRP2 4.7053 6.4317 4.0512 4.8789
THP-1 GDSC1; CTRP2 4.7637 5.8179 4.4045 3.2854
Kasumi-2 CTRP2 4.7992 11.5751 1.5725 14.9034
KYO-1 CTRP2 4.8814 5.6657 4.5893 2.2529
OCI-M1 GDSC1; CTRP2 4.9056 5.5895 4.649 1.9507
PL-21 GDSC1 4.9226 7.0678 0.6669 0.3121
HEL GDSC1; CTRP2 4.963 7.1291 3.9335 4.8289
MOLP-2 CTRP2 4.9663 6.607 4.1971 3.7153
ME1 CTRP2 5.0139 5.9361 4.5729 2.0417
P3HR-1 CTRP2 5.0301 7.8364 3.6364 5.9457
MHH-CALL-3 CTRP2 5.0556 6.6079 4.272 3.2253
CMK CTRP2 5.1656 6.4385 4.4456 2.2924
KMM-1 CTRP2 5.3989 9.4121 3.1485 7.3082
Karpas-620 GDSC1; CTRP2 5.7632 7.5097 4.3469 1.8
BL-41 GDSC1; CTRP2 6.2323 7.8506 4.4639 0.8918
REC-1 CTRP2 6.2366 9.2371 3.8388 3.1752
Toledo CTRP2 6.6007 8.3814 4.4254 0.7383
Raji GDSC1; CTRP2 6.8738 8.1746 4.6207 0.1755
Reh GDSC1; CTRP2 7.2836 8.6609 4.6012 0.1157
⏷ Show the Full List of 213 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 4.5391 5.5808 4.2906 4.3013
TE15 CTRP2 4.6903 5.5076 4.4775 3.1682
TE-6 GDSC1 1.978 3.9512 0.5332 4.5532
TE-8 GDSC1 2.9225 5.3082 0.4823 2.8769
OE21 GDSC1; CTRP2 3.4986 4.9397 3.3849 10.6935
T.T GDSC1 3.6371 5.169 0.8598 0.3246
KYSE-270 GDSC1 3.9161 6.072 0.6406 0.8708
TE-5 GDSC1; CTRP2 4.0075 5.3782 3.8068 7.6302
TE-11 GDSC1; CTRP2 4.0816 6.6204 3.3588 9.1928
TE-4 GDSC1; CTRP2 4.2787 5.8822 3.8912 6.5612
TE-15 GDSC1 4.2817 6.2199 0.7288 0.393
KYSE-30 CTRP2 4.3272 7.4135 3.2196 9.1764
KYSE-70 GDSC1; CTRP2 4.3865 5.2172 4.2728 4.7902
TE-9 GDSC1; CTRP2 4.4185 5.7059 4.112 5.3227
KYSE-410 GDSC1; CTRP2 4.4191 7.2653 3.3778 8.3132
OE33 GDSC1; CTRP2 4.4218 7.7916 3.1228 9.3643
TE-10 GDSC1; CTRP2 4.4299 6.0646 3.962 5.8936
KYSE-510 GDSC1; CTRP2 4.5734 6.1321 4.0712 5.1006
KYSE-520 GDSC1; CTRP2 4.7211 5.6185 4.4577 3.1704
OE19 GDSC1; CTRP2 4.7421 10.4955 2.063 13.0644
KYSE-180 GDSC1; CTRP2 4.7582 5.9277 4.3463 3.5377
TE-1 GDSC1; CTRP2 4.9997 6.3752 4.3414 3.0422
KYSE-450 GDSC1; CTRP2 5.0763 7.951 3.6176 5.936
EC-GI-10 GDSC1; CTRP2 5.1104 6.2885 4.4765 2.2627
KYSE-140 GDSC1; CTRP2 5.1573 7.7212 3.7989 5.0216
COLO 680N GDSC1; CTRP2 5.1691 7.6931 3.8225 4.9004
TE-14 CTRP2 5.3144 18.2614 -1.3405 23.4901
KYSE-150 GDSC1; CTRP2 5.3439 6.4697 4.5633 1.5119
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 8.9885 29.2661 -3.9573 23.4533
HPAC GDSC1; CTRP2 1.7287 2.6463 1.7284 22.0907
SNU-213 CTRP2 3.1381 5.66 2.7685 14.0298
Panc 10.05 GDSC1; CTRP2 3.6068 5.6649 3.2711 10.7953
PL4 GDSC1 3.7307 5.3477 0.8316 0.3581
Hs 766T GDSC1 3.815 5.6115 0.7695 0.493
MZ-PC-1 GDSC1 3.9587 6.1769 0.6188 0.9232
BxPC-3 GDSC1; CTRP2 3.9846 5.9961 3.5382 8.7267
Capan-1 GDSC1; CTRP2 4.0051 6.3713 3.3952 9.2395
Capan-2 GDSC1; CTRP2 4.0141 6.5963 3.3024 9.5884
Panc 08.13 GDSC1; CTRP2 4.1641 6.1565 3.6527 7.805
PK-59 CTRP2 4.1917 6.4019 3.5691 8.0706
HuP-T4 GDSC1; CTRP2 4.1982 5.9334 3.7862 7.1867
MIA PaCa-2 GDSC1; CTRP2 4.2961 5.1955 4.182 5.3915
Panc 03.27 GDSC1; CTRP2 4.328 5.1325 4.2369 5.0948
PaTu 8988s CTRP2 4.3398 5.6153 4.069 5.7004
DAN-G GDSC1; CTRP2 4.3854 5.7184 4.0724 5.5658
AsPC-1 GDSC1; CTRP2 4.4858 5.8813 4.102 5.1902
PaTu 8988t GDSC1; CTRP2 4.4944 5.0265 4.449 3.8224
SU.86.86 GDSC1; CTRP2 4.5054 5.2697 4.3823 4.0371
Panc 04.03 GDSC1; CTRP2 4.5706 5.559 4.3325 4.0534
CFPAC-1 GDSC1; CTRP2 4.5843 6.5134 3.8984 5.7855
PSN1 GDSC1; CTRP2 4.6079 6.2604 4.043 5.1351
PaTu 8902 GDSC1; CTRP2 4.6455 5.5139 4.4291 3.4757
HuP-T3 GDSC1; CTRP2 4.6601 6.273 4.0864 4.8355
KP-1N GDSC1 4.6937 6.5507 0.7622 0.2016
QGP-1 GDSC1; CTRP2 4.716 6.6923 3.933 5.3468
HPAF-II GDSC1; CTRP2 4.7243 7.1446 3.7169 6.2299
Panc 02.03 GDSC1; CTRP2 4.8003 5.7258 4.4837 2.8745
Panc 05.04 CTRP2 4.8143 7.0655 3.8362 5.5407
SW1990 GDSC1; CTRP2 4.8592 6.1429 4.3341 3.3634
YAPC GDSC1; CTRP2 4.8877 6.0192 4.4209 2.9398
PK-45H CTRP2 4.9084 5.8862 4.5055 2.5422
SUIT-2 GDSC1; CTRP2 4.9225 6.3978 4.2636 3.5253
L3.3 CTRP2 5.189 6.2484 4.5583 1.7807
KP-4 GDSC1; CTRP2 5.1947 6.9562 4.2107 3.2245
TCC-Pan2 CTRP2 5.2181 8.5414 3.4385 6.4218
KP-3 GDSC1; CTRP2 5.3652 8.1238 3.7632 4.7972
KP-2 CTRP2 7.1002 8.7485 4.5006 0.3126
SNU-410 CTRP2 8.1184 9.939 4.46 0.1335
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 74 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 -0.936 8.0209 -2.482 42.6643
Hs 940.T GDSC1; CTRP2 1.7405 3.2961 1.7273 22.055
SH-4 GDSC1 2.3608 4.8709 0.3489 4.9518
MMAc-SF GDSC1 2.6323 5.0034 0.4543 3.6038
LB373-MEL-D GDSC1 2.7475 4.484 0.7432 1.5675
VMRC-MELG GDSC1 3.0751 4.6179 0.8397 0.7277
Mel Ho GDSC1; CTRP2 3.0967 4.3697 3.0578 13.1076
COLO 679 GDSC1 3.1531 5.0485 0.7061 1.2654
COLO 783 GDSC1 3.1813 4.6611 0.8673 0.5422
GAK GDSC1 3.3034 5.0421 0.7746 0.8103
LB2518-MEL GDSC1 3.3063 4.6452 0.9215 0.3042
G-mel GDSC1 3.3684 4.9241 0.8451 0.5014
A-431 GDSC1 3.5166 5.649 0.6324 1.2431
SK-MEL-3 GDSC1; CTRP2 3.5615 5.1108 3.4074 10.4207
Hs 938.T GDSC1 3.5716 5.1462 0.8433 0.398
MZ-MEL-7 GDSC1 3.5795 5.1738 0.8365 0.4138
HMV-II GDSC1 3.6369 5.846 0.6086 1.2368
CP66-MEL GDSC1 3.6387 4.8574 0.9672 0.1122
A-388 GDSC1 3.7109 5.732 0.6837 0.8561
CP50-MEL-B GDSC1 3.7292 5.265 0.86 0.2882
IST-MEL1 GDSC1 3.7509 5.4201 0.8135 0.3975
SK-MEL-24 GDSC1; CTRP2 3.7588 5.509 3.4918 9.5283
WM278 GDSC1 3.7697 5.529 0.7817 0.4795
451Lu GDSC1 3.7778 5.4306 0.8198 0.3687
M14 GDSC1 3.8132 5.2809 0.8848 0.2083
IGR-1 GDSC1; CTRP2 3.8255 5.1659 3.6792 8.6369
RPMI-7951 GDSC1; CTRP2 3.8337 5.0647 3.7175 8.4732
WM1552C GDSC1 3.835 5.7246 0.7363 0.5857
UACC-257 GDSC1; CTRP2 4.0758 4.8467 4.034 6.5961
DJM-1 GDSC1 4.0787 5.8073 0.7985 0.3042
COLO 792 GDSC1; CTRP2 4.1686 5.3236 4 6.4411
WM115 GDSC1; CTRP2 4.1725 4.8993 4.1282 5.9612
A101D GDSC1; CTRP2 4.1935 5.0148 4.1237 5.9124
CHL-1 GDSC1 4.232 6.2435 0.702 0.4841
Hs 688(A).T CTRP2 4.2415 5.9692 3.8149 6.9605
MeWo GDSC1; CTRP2 4.257 5.5171 4.022 6.1083
G-361 GDSC1; CTRP2 4.2677 5.9841 3.835 6.8127
Hs 895.T CTRP2 4.281 4.9865 4.2263 5.2757
COLO 800 GDSC1; CTRP2 4.2983 5.6044 4.0301 5.9637
Hs 294T CTRP2 4.3094 4.8686 4.2825 4.9885
IGR-37 GDSC1; CTRP2 4.3552 4.98 4.3088 4.7522
A2058 GDSC1; CTRP2 4.3575 4.9367 4.3212 4.7012
MZ-MEL-2 GDSC1 4.3585 6.4801 0.6655 0.5269
IGR-39 CTRP2 4.3786 4.8916 4.3531 4.5226
UACC-62 GDSC1; CTRP2 4.4276 4.9396 4.3967 4.2157
HT-144 GDSC1; CTRP2 4.4291 4.9644 4.3929 4.2241
SK-MEL-5 GDSC1; CTRP2 4.4578 4.9526 4.4267 4.0152
Malme-3M CTRP2 4.4891 5.8768 4.1074 5.1603
WM793 GDSC1; CTRP2 4.5023 5.104 4.4354 3.8479
Mel JuSo GDSC1; CTRP2 4.5148 5.1614 4.4307 3.8282
K029AX CTRP2 4.5221 4.956 4.4959 3.5697
HMCB CTRP2 4.5225 4.9972 4.487 3.6
SK-MEL-30 GDSC1; CTRP2 4.5568 5.0439 4.5124 3.4038
LOX-IMVI GDSC1; CTRP2 4.5646 5.0192 4.5274 3.326
WM983B CTRP2 4.5805 7.9101 3.2087 8.6599
CJM [Human melanoma] CTRP2 4.5954 5.1836 4.5104 3.297
WM266-4 CTRP2 4.6071 5.0981 4.5515 3.1097
Hs 852.T CTRP2 4.6248 5.2474 4.5185 3.1826
SK-MEL-2 GDSC1; CTRP2 4.6457 13.1895 0.635 18.7207
RVH-421 GDSC1; CTRP2 4.6572 5.2722 4.5435 2.9965
Hs 936.T CTRP2 4.6837 5.0568 4.6473 2.5305
Hs 839.T CTRP2 4.6976 5.2046 4.6127 2.6191
WM1799 CTRP2 4.7109 5.2905 4.5928 2.659
A-375 GDSC1; CTRP2 4.7224 6.1371 4.2109 4.1788
COLO 829 GDSC1; CTRP2 4.7272 6.4212 4.0766 4.7249
IPC-298 GDSC1; CTRP2 4.7371 5.187 4.6616 2.3218
Hs 944.T CTRP2 4.7974 6.805 3.9506 5.0978
WM88 CTRP2 4.8158 6.1344 4.2989 3.6046
WM35 GDSC1 4.8319 6.5834 0.7985 0.1265
WT2-iPS GDSC1; CTRP2 4.8376 5.4032 4.6729 2.0126
SK-MEL-1 GDSC1; CTRP2 4.8861 5.5814 4.6347 2.054
MDA-MB-435S CTRP2 4.909 5.6477 4.6236 2.0489
SK-MEL-28 GDSC1; CTRP2 5.2599 6.5385 4.4684 2.0354
SK-MEL-31 CTRP2 5.3079 6.4571 4.5438 1.6467
⏷ Show the Full List of 74 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC1 2.8457 4.952 0.5953 2.2977
OACM5.1 C GDSC1 3.2316 6.4252 0.1613 4.3963
KYAE-1 GDSC1 3.4771 5.6999 0.5946 1.465
KYSE-50 GDSC1 3.6058 5.2435 0.8215 0.4447
HCE-4 GDSC1 3.8922 5.7853 0.7365 0.5529
KYSE-220 GDSC1 4.1822 6.1393 0.7203 0.4568
SK-GT-4 GDSC1 4.1951 6.6215 0.5492 1.0165
FLO-1 GDSC1 4.3149 7.0999 0.4176 1.4624
TE-12 GDSC1 4.3219 6.8758 0.506 1.0896
OACP4 C GDSC1 4.4005 6.9639 0.5054 1.0341
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 4.4424 5.7868 4.1008 5.3054
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-MC-IXC GDSC1 2.4844 3.7144 0.932 0.8755
SJNB-6 GDSC1 2.9472 5.0144 0.6211 1.9891
CHP-134 GDSC1 2.964 4.8389 0.7022 1.5087
SK-N-FI GDSC1 3.2018 4.8327 0.8114 0.7415
MHH-NB-11 GDSC1 3.2055 4.815 0.8197 0.7053
SJNB-13 GDSC1 3.2931 4.9854 0.7917 0.7488
NH-12 GDSC1 3.3113 5.6211 0.5487 1.9003
IMR-5 GDSC1 3.4959 5.2813 0.7642 0.7047
NB(TU)1 GDSC1 3.4998 5.1574 0.8115 0.5346
SJNB-14 GDSC1 3.6203 5.1323 0.8665 0.3145
KP-N-YN GDSC1 3.7272 5.6559 0.7187 0.7129
LA-N-6 GDSC1 3.7553 5.4341 0.8102 0.4046
SJNB-7 GDSC1 3.7761 5.388 0.8342 0.3325
SK-N-DZ GDSC1; CTRP2 3.7803 5.2392 3.6071 9.0358
TGW GDSC1 3.9092 5.328 0.9024 0.1534
SJNB-10 GDSC1 4.0155 5.8696 0.7534 0.4419
SK-N-BE(2)-M17 GDSC1 4.031 5.6007 0.8526 0.2087
KP-N-YS GDSC1 4.1065 5.8139 0.8063 0.278
SJNB-5 GDSC1 4.1099 5.8647 0.79 0.3125
NB69 GDSC1 4.1361 5.8499 0.8045 0.2723
CHP-212 GDSC1; CTRP2 4.1783 5.7203 3.8563 6.9646
Kelly GDSC1; CTRP2 4.1882 5.2718 4.0393 6.2374
SK-N-AS GDSC1; CTRP2 4.1924 5.098 4.0994 6.0036
SK-N-SH GDSC1; CTRP2 4.2115 5.631 3.928 6.5961
SiMa GDSC1; CTRP2 4.2245 5.9007 3.8275 6.9548
NH-6 CTRP2 4.2414 6.8126 3.4262 8.5289
SJNB-17 GDSC1 4.2991 6.4245 0.6628 0.5635
SJNB-12 GDSC1 4.3142 6.3238 0.7044 0.4416
KP-N-SI9s CTRP2 4.3733 4.9648 4.3321 4.6134
GOTO GDSC1 4.3929 6.1129 0.8055 0.2001
NB1 GDSC1; CTRP2 4.4079 8.6081 2.7078 11.1161
CHP-126 CTRP2 4.4343 12.2434 0.9246 18.1232
SK-N-BE(2) CTRP2 4.4975 5.5256 4.2713 4.487
GI-ME-N GDSC1 5.1369 7.6954 0.5266 0.5547
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; CTRP2 2.3963 4.0598 2.3518 17.7925
SNU-1079 CTRP2 3.3342 4.9524 3.2024 11.8523
SNU-478 CTRP2 4.0806 5.6451 3.784 7.5111
SNU-308 CTRP2 4.3942 6.1734 3.8762 6.3287
SNU-869 CTRP2 4.4913 5.164 4.4043 3.9951
HuH-28 CTRP2 4.6278 5.6068 4.3695 3.7588
SNU-245 CTRP2 5.1766 8.3352 3.5078 6.2078
SNU-1196 CTRP2 5.2904 9.844 2.8464 8.7661
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC1 2.0649 6.6153 -0.7087 13.5078
MDA-MB-175-VII GDSC1 2.805 5.7445 0.2196 4.862
HCC1954 GDSC1; CTRP2 3.0401 5.1043 2.8404 14.0535
MRK-nu-1 GDSC1 3.0513 4.496 0.8759 0.6014
DU4475 GDSC1 3.0913 4.2168 0.9925 0.2128
MDA-MB-436 GDSC1 3.1493 4.8553 0.7803 0.9189
Evsa-T GDSC1 3.1962 4.8377 0.8071 0.7634
UACC-812 GDSC1 3.2893 5.2339 0.6943 1.1797
HCC202 GDSC1 3.3289 5.7914 0.4869 2.2214
MDA-MB-453 GDSC1; CTRP2 3.3297 5.231 3.119 12.1679
EFM-192A GDSC1 3.3529 4.846 0.8674 0.4382
HCC70 GDSC1 3.3707 5.3685 0.6776 1.1764
HCC1187 GDSC1 3.4992 5.0975 0.8331 0.4656
BT-483 GDSC1 3.5679 5.0325 0.8821 0.2965
HCC2218 GDSC1 3.6716 5.549 0.7359 0.6881
MDA-MB-468 GDSC1; CTRP2 3.7529 5.3348 3.5462 9.3419
AU565 GDSC1; CTRP2 3.8194 6.1147 3.316 10.0383
HCC1395 GDSC1; CTRP2 3.8631 5.9611 3.4261 9.4907
COLO 824 GDSC1 3.9038 6.0635 0.6387 0.8869
Hs 578T GDSC1; CTRP2 3.9467 5.2123 3.7967 7.8449
MFM-223 GDSC1 3.962 5.241 0.9494 0.0823
MDA-MB-330 GDSC1 3.9949 6.8286 0.3815 1.9551
BT-474 GDSC1; CTRP2 4.0633 5.4104 3.8554 7.2869
HMC-1-8 CTRP2 4.0861 5.0133 4.0069 6.6608
OCUB-M GDSC1 4.1042 5.8096 0.807 0.2773
HCC1500 GDSC1; CTRP2 4.1478 7.3754 3.0675 10.2182
CAL-85-1 GDSC1; CTRP2 4.252 5.6134 3.9778 6.2925
HCC1599 GDSC1 4.2724 5.8399 0.8557 0.1483
SK-BR-3 CTRP2 4.2728 6.6022 3.5561 7.9239
UACC-893 GDSC1 4.3371 6.5751 0.6232 0.6643
T-47D GDSC1; CTRP2 4.344 6.5123 3.6682 7.2954
ZR-75-1 CTRP2 4.3631 5.1959 4.2546 4.926
CAL-148 GDSC1; CTRP2 4.3858 5.519 4.1572 5.2326
YMB-1-E GDSC1 4.4235 6.3359 0.7401 0.316
MDA-MB-361 GDSC1; CTRP2 4.4675 8.0349 3.0448 9.5873
Hs 578Bst CTRP2 4.5175 6.8173 3.6879 6.8074
MDA-MB-415 GDSC1; CTRP2 4.5278 5.713 4.2205 4.6091
HCC1569 GDSC1 4.5622 6.7074 0.6613 0.449
HCC1428 GDSC1; CTRP2 4.5851 5.0521 4.541 3.2142
ZR-75-30 GDSC1; CTRP2 4.6011 5.4438 4.4138 3.6529
HCC1143 CTRP2 4.6213 6.1262 4.1203 4.7861
HCC38 GDSC1; CTRP2 4.6297 5.596 4.3763 3.7267
MCF-7 GDSC1; CTRP2 4.6492 6.5777 3.9278 5.5164
EFM-19 GDSC1 4.72 7.1658 0.5578 0.6612
MDA-MB-231 GDSC1; CTRP2 4.7988 6.0043 4.347 3.4424
HCC1806 GDSC1; CTRP2 4.8492 6.7213 4.0382 4.622
BT-549 GDSC1; CTRP2 4.881 5.8438 4.5015 2.6185
CAMA-1 GDSC1; CTRP2 4.8822 6.074 4.3889 3.0851
CAL-120 GDSC1; CTRP2 4.9431 5.9043 4.5274 2.3768
JIMT-1 CTRP2 4.9623 5.85 4.5713 2.1531
HCC1419 GDSC1; CTRP2 5.0786 6.1587 4.5155 2.1581
HCC1937 GDSC1; CTRP2 5.1043 7.6481 3.7921 5.1492
CAL-51 GDSC1; CTRP2 5.1538 7.1336 4.0895 3.8075
KPL-1 CTRP2 5.181 17.0651 -0.8525 22.3983
BT-20 GDSC1; CTRP2 6.1122 9.3431 3.7066 3.8654
HDQ-P1 GDSC1; CTRP2 7.016 9.2356 4.2749 0.8938
MDA-MB-157 GDSC1; CTRP2 9.066 19.769 0.7034 11.142
BT 416 CTRP2 -2.0075 6.9997 -3.2621 47.8162
BT 216 CTRP2 1.4452 3.988 1.3463 24.3144
BT 145 CTRP2 2.1747 4.4557 2.0515 19.5409
BT 231 CTRP2 2.4495 5.8887 1.9441 19.1029
BT 286 CTRP2 2.8463 5.0164 2.6531 15.3189
BT 245 CTRP2 3.1153 9.3037 1.1515 20.3319
BT 359 CTRP2 3.1676 7.5211 2.0299 16.8124
BT 159 CTRP2 3.3413 4.9218 3.2178 11.7752
BT 228 CTRP2 3.6493 5.6376 3.3269 10.4635
BT 271 CTRP2 3.7316 7.4769 2.6145 13.0624
BT 428 CTRP2 3.7832 6.5565 3.0868 11.0381
BT 187 CTRP2 3.8098 6.2328 3.2556 10.3006
BT 232 CTRP2 3.8255 6.0117 3.3657 9.8273
BT 172 CTRP2 3.893 7.7254 2.655 12.5072
BT 139 CTRP2 4.092 5.8119 3.7278 7.6981
BT 440 CTRP2 4.1465 5.7672 3.8035 7.2563
BT 330 CTRP2 4.1719 5.7304 3.8454 7.0244
BT147 CTRP2 4.1985 5.8243 3.8335 6.9998
BT 504 CTRP2 4.2088 13.7665 -0.0311 21.9107
BT 131 CTRP2 4.2594 6.1696 3.7433 7.2005
BT 333 CTRP2 4.2964 6.3188 3.7118 7.2347
BT164 CTRP2 4.3164 5.378 4.1391 5.4947
BT 340 CTRP2 4.42 5.9504 4.0045 5.7473
BT 239 CTRP2 4.4233 4.9468 4.3905 4.251
BT 482 CTRP2 4.4727 5.9253 4.0687 5.3569
BT 179 CTRP2 4.4974 7.3454 3.4114 7.9982
BT 498 CTRP2 4.5721 5.7712 4.2388 4.4235
BT 422 CTRP2 4.5848 6.0968 4.0991 4.9598
BT 112 CTRP2 4.5988 5.0337 4.5609 3.1008
BT 224 CTRP2 4.6129 6.7563 3.8067 6.0997
BT 320 CTRP2 4.7482 5.9525 4.3248 3.6494
BT 328 CTRP2 4.8207 7.7005 3.5256 6.8291
BT 444 CTRP2 5.2181 6.7785 4.3175 2.7361
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.6631 5.1401 3.5098 9.7423
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AM-38 GDSC1; CTRP2 1.4704 4.2377 1.3309 24.2873
H4 GDSC1 2.7237 4.6858 0.6455 2.1846
D-336MG GDSC1 3.0144 6.4685 0.0141 5.8295
PFSK-1 GDSC1 3.0146 9.9082 -1.6289 16.4074
GI-1 GDSC1 3.0161 5.626 0.3943 3.276
DK-MG GDSC1 3.0464 4.988 0.6807 1.5213
D-263MG GDSC1 3.1291 4.4302 0.931 0.3618
MOG-G-CCM GDSC1 3.157 5.3261 0.5953 1.8451
CAS-1 GDSC1; CTRP2 3.1858 5.1424 2.9885 13.0757
D-566MG GDSC1 3.1982 5.0899 0.7101 1.1975
M059J GDSC1 3.3198 4.9418 0.8191 0.6239
Onda 11 GDSC1 3.4245 5.7947 0.5319 1.848
LN-18 GDSC1; CTRP2 3.4786 4.1513 3.475 10.4436
D-423MG GDSC1 3.4798 5.9492 0.4952 1.9758
D-392MG GDSC1 3.4919 5.7317 0.5887 1.4782
D-542MG GDSC1 3.6336 5.3846 0.7812 0.556
SK-MG-1 GDSC1 3.6839 5.181 0.8728 0.2752
LNZTA3WT4 GDSC1 3.7333 5.4784 0.786 0.4857
KNS-81-FD GDSC1 3.7443 5.3625 0.8314 0.3528
KG-1-C CTRP2 3.7896 5.4828 3.5344 9.2797
LN-405 GDSC1 3.8063 5.2436 0.895 0.1909
D-247MG GDSC1 3.8217 5.7588 0.7185 0.6526
KINGS-1 GDSC1 3.8218 6.2237 0.5426 1.361
KS-1 [Human Krukenberg tumour] GDSC1 3.8649 6.2792 0.5399 1.3325
SF268 GDSC1; CTRP2 3.9367 5.8049 3.5676 8.7413
Onda 10 GDSC1 3.9802 5.6189 0.8282 0.2724
Hs 683 GDSC1; CTRP2 4.1233 5.1048 4.0221 6.4926
GaMG GDSC1; CTRP2 4.1588 7.1829 3.1702 9.7718
LN-229 GDSC1; CTRP2 4.2563 5.7389 3.93 6.4674
SF539 GDSC1; CTRP2 4.2808 5.6577 3.9896 6.1687
42-MG-BA GDSC1; CTRP2 4.3082 5.3991 4.1223 5.5815
M059K CTRP2 4.3262 4.9789 4.2775 4.9533
SW1088 GDSC1; CTRP2 4.3453 5.7767 4.0058 5.9338
SNU-466 CTRP2 4.3841 4.9317 4.3511 4.5125
T98G GDSC1; CTRP2 4.3958 5.6193 4.1258 5.3285
A-172 GDSC1; CTRP2 4.3982 5.9301 3.9917 5.8538
GOS-3 CTRP2 4.4019 8.0158 2.9943 9.9415
MOG-G-UVW GDSC1 4.4067 6.7063 0.6027 0.6904
TM-31 CTRP2 4.4484 4.935 4.4202 4.0676
GMS-10 CTRP2 4.4575 4.8939 4.4379 3.9769
D283 Med GDSC1; CTRP2 4.4764 6.0566 4.0118 5.5772
SNU-1105 CTRP2 4.4802 5.2556 4.3604 4.1916
KNS-81 CTRP2 4.4837 5.085 4.421 3.9562
NMC-G1 GDSC1; CTRP2 4.4854 5.1425 4.405 4.0097
YKG-1 GDSC1; CTRP2 4.5249 4.978 4.4941 3.5673
KNS-42 GDSC1; CTRP2 4.6064 5.1724 4.5262 3.2061
U-251MG GDSC1; CTRP2 4.6101 5.3127 4.4774 3.3811
U-118MG GDSC1; CTRP2 4.6173 5.2787 4.4985 3.2798
KNS-60 CTRP2 4.6225 4.989 4.5978 2.8963
SNB-75 GDSC1; CTRP2 4.6651 6.5743 3.9442 5.4128
D-502MG GDSC1 4.6979 6.5452 0.7655 0.1955
KALS-1 GDSC1; CTRP2 4.7076 5.671 4.4198 3.357
ONS-76 GDSC1; CTRP2 4.7171 5.6395 4.4439 3.236
DBTRG-05MG GDSC1; CTRP2 4.7368 11.2421 1.6856 14.5862
CCF-STTG1 CTRP2 4.7505 5.2114 4.6665 2.2654
SF295 GDSC1; CTRP2 4.8884 6.067 4.3979 3.0341
SNU-626 CTRP2 4.8973 5.7388 4.5681 2.305
SNU-489 CTRP2 5.1209 6.3552 4.4516 2.3478
YH-13 GDSC1; CTRP2 5.1358 6.6909 4.296 2.9738
GB-1 GDSC1; CTRP2 5.166 6.5272 4.4017 2.4755
8-MG-BA GDSC1; CTRP2 5.191 8.396 3.4892 6.2594
SW1783 GDSC1; CTRP2 5.2222 8.0937 3.6653 5.4627
SNU-201 CTRP2 5.2263 7.1555 4.1363 3.4799
Becker GDSC1; CTRP2 5.3602 7.1331 4.2501 2.7762
SF126 GDSC1; CTRP2 5.4587 8.1141 3.8397 4.3183
Daoy GDSC1; CTRP2 5.6913 9.2006 3.4777 5.4367
U-87MG ATCC GDSC1; CTRP2 5.8006 8.1457 4.0697 2.8468
SNU-738 CTRP2 6.2138 8.946 3.9607 2.7307
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 2.8783 5.7403 0.2651 4.396
TGBC1TKB GDSC1 3.3951 4.7696 0.9106 0.2947
ETK-1 GDSC1 4.3161 6.2256 0.7395 0.3545
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-265 CTRP2 2.8969 4.0327 2.881 14.3603
JHUEM-2 CTRP2 3.8356 6.2446 3.2773 10.1472
RL95-2 GDSC1; CTRP2 3.9547 5.2813 3.7829 7.8724
HEC-1-A CTRP2 4.0362 8.1721 2.5773 12.4878
MFE-296 GDSC1; CTRP2 4.2105 5.9586 3.7878 7.1482
JHUEM-3 CTRP2 4.2788 5.745 3.9508 6.3261
JHUEM-1 CTRP2 4.3519 4.899 4.3228 4.713
EN GDSC1; CTRP2 4.4095 4.9346 4.3782 4.3375
ESS-1 GDSC1; CTRP2 4.4619 5.0216 4.4148 4.0446
HEC-6 CTRP2 4.5814 6.2085 4.0425 5.1992
JHUEM-7 CTRP2 4.5859 5.13 4.5183 3.2949
AN3-CA GDSC1; CTRP2 4.6269 5.8778 4.2436 4.2689
MFE-280 GDSC1 4.638 6.6403 0.7121 0.3066
HEC-59 CTRP2 4.64 8.2508 3.0928 9.0172
HEC-50B CTRP2 4.7189 5.5134 4.5037 2.9905
HEC-151 CTRP2 4.7191 5.2991 4.5979 2.6169
EFE-184 CTRP2 4.8781 5.8061 4.5174 2.5587
HEC-108 CTRP2 4.8887 5.8871 4.4872 2.6612
MFE-319 GDSC1; CTRP2 4.9702 5.874 4.5663 2.1576
HEC-1-B CTRP2 5.1463 6.781 4.2595 3.1078
HEC-251 CTRP2 5.3444 8.1837 3.7172 5.0256
KLE GDSC1; CTRP2 5.4157 7.9198 3.9032 4.1262
Ishikawa (Heraklio) 02 ER- CTRP2 5.3607 7.0283 4.3021 2.5603
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 0.3472 2.8956 -3.7808 0.9381
HA7-RCC GDSC1 2.317 4.2455 0.612 3.1662
SN12C GDSC1 2.633 4.7708 0.5589 2.8985
A-498 GDSC1 2.65 3.9094 0.9296 0.7128
KTCTL-26A GDSC1 2.6501 5.7756 0.1093 5.9904
SW13 GDSC1 2.818 4.5966 0.7311 1.5395
KTCTL-1M GDSC1 3.0299 6.1678 0.1606 4.7968
KMRC-3 CTRP2 3.0622 7.3063 2.0184 17.1316
LB2241-RCC GDSC1 3.1507 5.8811 0.3562 3.2845
KTCTL-13 GDSC1 3.1912 5.3763 0.5912 1.8228
A-704 GDSC1 3.3475 5.0292 0.7978 0.6842
786-O GDSC1; CTRP2 3.6614 5.1576 3.5028 9.7727
UO-31 GDSC1; CTRP2 3.6725 6.2003 3.1268 11.1712
KTCTL-195 GDSC1 3.8747 5.8997 0.6878 0.7259
BB65-RCC GDSC1 3.8786 5.8185 0.7192 0.6163
SW156 GDSC1 3.9155 6.1921 0.595 1.0511
LB996-RCC GDSC1 3.9915 5.7512 0.7862 0.366
NCC021 GDSC1 4.0773 6.0696 0.7054 0.5501
CAL-54 GDSC1; CTRP2 4.1816 5.4 3.9864 6.4552
KMRC-20 GDSC1; CTRP2 4.2493 5.7526 3.9168 6.5378
KMRC-1 GDSC1; CTRP2 4.2754 5.3093 4.1204 5.6818
KMRC-2 CTRP2 4.2874 7.2102 3.2803 9.0183
KTCTL-140 GDSC1 4.3257 6.5012 0.6455 0.6016
VMRC-RCW GDSC1; CTRP2 4.3298 7.6186 3.1222 9.5729
TUHR4TKB CTRP2 4.3467 5.5535 4.1019 5.5539
TK-10 GDSC1 4.367 6.3058 0.7301 0.3577
BFTC-909 GDSC1; CTRP2 4.4062 5.9765 3.9787 5.8857
RXF 393L GDSC1 4.6094 6.8631 0.6239 0.5264
VMRC-RCZ GDSC1; CTRP2 4.7119 5.3564 4.5661 2.7605
KTCTL-21 GDSC1 4.7873 7.0968 0.6077 0.4926
RCC10RGB GDSC1; CTRP2 4.8094 5.5054 4.5975 2.3873
769-P GDSC1; CTRP2 4.8976 5.9598 4.4592 2.7586
Caki-1 GDSC1; CTRP2 5.2877 8.1983 3.6653 5.3438
ACHN GDSC1; CTRP2 5.3247 6.723 4.4257 2.1068
SNU-1272 CTRP2 5.3503 7.0227 4.2972 2.5976
OS-RC-2 GDSC1; CTRP2 5.3816 7.216 4.2252 2.8446
LB1047-RCC GDSC1 5.4997 7.809 0.6175 0.2523
Caki-2 CTRP2 5.9774 10.2521 2.4017 4.4402
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT115 GDSC1; CTRP2 2.3467 3.8771 2.3183 18.068
SK-CO-1 CTRP2 2.5828 9.4155 0.5767 23.7786
HCT 15 GDSC1; CTRP2 2.9271 4.3701 2.8768 14.2767
T84 GDSC1; CTRP2 2.9864 5.3257 2.7158 14.6693
SNU-C1 GDSC1; CTRP2 3.1228 5.556 2.7882 14.0001
OUMS-23 CTRP2 3.1697 4.6674 3.0877 12.7706
SNU-1040 GDSC1 3.2241 4.6509 0.888 0.4447
GP5d GDSC1 3.2298 5.0191 0.7519 0.9719
SNU-1033 CTRP2 3.322 5.4254 3.0484 12.4513
SW837 GDSC1 3.6683 5.6636 0.6918 0.8564
LS1034 GDSC1; CTRP2 3.6828 4.9666 3.579 9.4323
LS513 GDSC1; CTRP2 3.72 4.8066 3.6564 9.042
COLO 320HSR GDSC1 3.8387 5.5185 0.8115 0.3645
SNU-81 GDSC1 4.0164 5.5358 0.8695 0.1825
SW1463 GDSC1 4.0568 5.8547 0.774 0.3702
CaR-1 GDSC1 4.0853 5.7371 0.8251 0.2459
NCI-H747 GDSC1 4.0937 6.2014 0.664 0.6716
LS180 GDSC1; CTRP2 4.1147 5.5896 3.8422 7.1931
HCC2998 GDSC1 4.1335 6.04 0.7372 0.433
CL-11 GDSC1; CTRP2 4.2332 5.9749 3.8039 7.0255
LoVo GDSC1; CTRP2 4.2367 6.4735 3.5808 7.9119
C2BBe1 GDSC1; CTRP2 4.243 5.7211 3.9236 6.5281
SW948 GDSC1; CTRP2 4.2928 5.0161 4.2317 5.2204
HT-29 GDSC1; CTRP2 4.3397 5.3596 4.171 5.3078
COLO201 CTRP2 4.343 5.5109 4.1154 5.5114
SNU-61 GDSC1; CTRP2 4.3477 8.1859 2.861 10.6141
SNU-C2A CTRP2 4.4155 7.1825 3.4147 8.1689
SW48 GDSC1; CTRP2 4.4256 6.5927 3.7089 6.9342
SW626 GDSC1 4.4379 6.2835 0.7633 0.2644
HT-55 GDSC1; CTRP2 4.4456 5.4105 4.2641 4.6559
SNU-407 GDSC1; CTRP2 4.4536 5.9536 4.0366 5.5339
LS411N GDSC1; CTRP2 4.4674 5.9566 4.0491 5.4493
HCC-56 CTRP2 4.5193 4.955 4.493 3.5887
RKO GDSC1; CTRP2 4.5395 5.9062 4.1442 4.8862
CCK-81 GDSC1; CTRP2 4.5516 7.1499 3.5572 7.2724
HCT 8 CTRP2 4.5717 5.0424 4.529 3.2985
RCM-1 [Human ESC] GDSC1; CTRP2 4.6234 5.1865 4.5396 3.1066
NCI-H716 GDSC1; CTRP2 4.6807 5.4442 4.4959 3.1195
SNU-175 GDSC1; CTRP2 4.6986 6.8302 3.8491 5.7342
SW1116 GDSC1; CTRP2 4.7065 5.8877 4.3162 4.3758
CW-2 GDSC1; CTRP2 4.7396 6.4979 4.0503 4.8068
SNU-C4 CTRP2 4.8084 5.3141 4.6839 2.0425
COLO 320 CTRP2 4.8522 8.4038 3.202 8.1223
SW1417 GDSC1; CTRP2 4.8891 5.8219 4.5196 2.525
SNU-C5 GDSC1; CTRP2 4.9173 6.8539 4.0316 4.509
MDST8 GDSC1; CTRP2 4.9584 5.661 4.6618 1.782
DLD-1 CTRP2 5.0604 6.4073 4.3763 2.7776
COLO 678 GDSC1; CTRP2 5.0637 6.2711 4.447 2.4738
SW620 GDSC1; CTRP2 5.1481 6.5684 4.367 2.6533
SNU-C2B GDSC1 5.2294 7.7034 0.5578 0.4438
SNU-503 CTRP2 5.3122 6.9363 4.3113 2.6018
KM12 GDSC1; CTRP2 5.39 7.0116 4.3319 2.3902
COLO205 GDSC1; CTRP2 5.4382 8.0658 3.848 4.3182
HCT 116 GDSC1; CTRP2 5.6042 8.8033 3.6086 5.0368
GP2d CTRP2 6.1551 7.5968 4.5319 0.7382
LS123 GDSC1; CTRP2 6.8544 8.8051 4.373 0.724
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 3.6089 5.4834 0.7349 0.7345
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-761 CTRP2 1.9835 4.9329 1.7337 22.7777
SNU-182 CTRP2 2.494 6.8856 1.6074 20.243
Hep-G2/C3A GDSC1 2.9943 4.6415 0.7955 0.9986
JHH-1 GDSC1; CTRP2 3.0093 4.8267 2.8789 14.0097
Huh-7 GDSC1 3.1217 5.0045 0.7093 1.2843
HLE GDSC1 3.1859 5.5417 0.5198 2.2337
Hep-G2 CTRP2 3.1949 5.2232 2.9745 13.0997
Li-7 CTRP2 3.3855 5.38 3.1324 11.9536
JHH-7 GDSC1 3.5969 5.2867 0.8025 0.5081
HuH-1 GDSC1; CTRP2 4.0459 5.9878 3.1024 4.5089
JHH-5 CTRP2 4.1028 6.3497 3.5037 8.5569
SNU-878 CTRP2 4.1201 5.2111 3.9857 6.6356
HLF CTRP2 4.2574 5.2137 4.1339 5.6836
Hep 3B2.1-7 GDSC1; CTRP2 4.3422 5.6774 4.0454 5.7865
JHH-4 GDSC1; CTRP2 4.3666 7.8253 3.0553 9.7669
PLC/PRF/5 CTRP2 4.4391 5.1615 4.3485 4.3551
SNU-423 GDSC1; CTRP2 4.4563 5.1335 4.3762 4.2021
SNU-449 GDSC1; CTRP2 4.5299 5.2167 4.4279 3.7951
JHH-2 GDSC1; CTRP2 4.5314 7.926 3.1566 8.9832
JHH-6 GDSC1; CTRP2 4.7293 5.1041 4.6825 2.2658
SNU-387 GDSC1; CTRP2 4.7305 6.3526 4.1133 4.5651
SNU-475 GDSC1; CTRP2 4.7716 5.3005 4.6519 2.265
SNU-886 CTRP2 4.8298 14.9969 -0.1118 20.8562
SK-HEP-1 GDSC1; CTRP2 4.9934 5.8194 4.6136 1.9118
SNU-398 GDSC1; CTRP2 5.0423 7.0681 4.0308 4.2646
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 211 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2081 GDSC1 1.8798 3.8679 0.5054 5.0331
NCI-H345 GDSC1 2.1516 3.1981 0.9831 1.027
NCI-H82 GDSC1 2.5789 4.1793 0.7863 1.5578
NCI-H810 GDSC1; CTRP2 2.6293 4.2391 2.577 16.2672
NCI-H1436 GDSC1 2.6576 4.5432 0.6719 2.1283
NCI-H2141 GDSC1 2.6733 4.676 0.6228 2.4113
NCI-H3255 GDSC1 2.6735 4.8511 0.546 2.908
NCI-H322M GDSC1 2.7152 5.0032 0.502 3.1212
Lu-165 GDSC1 2.7565 4.1109 0.8979 0.7561
NCI-H2369 GDSC1 2.7735 5.3826 0.3655 3.9245
NCI-H847 GDSC1 2.8359 4.599 0.7389 1.4727
LCLC-97TM1 GDSC1; CTRP2 2.865 6.7285 2.0617 17.4901
Calu-3 GDSC1; CTRP2 2.8946 4.6716 2.7886 14.6869
LK-2 GDSC1 2.93 4.6085 0.7795 1.1452
NCI-H1836 GDSC1 2.9804 4.9396 0.6687 1.6711
NCI-H510A GDSC1 2.9926 4.5786 0.8193 0.8896
NCI-H290 GDSC1 3.003 4.9969 0.6561 1.7113
RERF-LC-KJ GDSC1 3.0171 4.711 0.7783 1.0573
NCI-H187 GDSC1 3.0226 4.149 0.991 0.2436
SBC-3 GDSC1 3.0279 4.7759 0.7575 1.1473
NCI-H720 GDSC1 3.0388 4.3175 0.9368 0.393
NCI-H1048 GDSC1 3.0628 5.196 0.6029 1.9299
A-427 GDSC1 3.0699 5.2945 0.5652 2.137
HCC95 CTRP2 3.1126 4.9218 2.9684 13.3712
UMC-11 GDSC1 3.1559 4.9482 0.747 1.0652
COR-L321 GDSC1 3.1704 4.9462 0.7542 1.0173
NCI-H2135 GDSC1 3.1724 4.6686 0.8609 0.5715
COR-L23 GDSC1 3.1933 4.6563 0.8738 0.5113
DMS 53 GDSC1; CTRP2 3.2105 5.456 2.9172 13.2643
COR-L303 GDSC1 3.2232 4.6808 0.8768 0.4826
NCI-H1666 GDSC1; CTRP2 3.2327 5.8519 2.8001 13.6408
NCI-H2803 GDSC1 3.2342 4.8841 0.8055 0.7398
HCC33 GDSC1 3.2392 4.8763 0.8106 0.7155
NCI-H1688 GDSC1 3.274 5.3043 0.6594 1.3653
NCI-H1304 GDSC1 3.2784 5.0535 0.7596 0.8943
COR-L88 GDSC1 3.3047 5.2396 0.6989 1.1425
NCI-H1781 GDSC1 3.3151 4.8676 0.8446 0.5356
NCI-H1944 GDSC1; CTRP2 3.3223 6.5489 2.6147 14.1098
NCI-H1703 GDSC1; CTRP2 3.3767 5.4166 3.1107 12.0599
NCI-H1568 GDSC1; CTRP2 3.3884 5.0884 3.225 11.6054
NCI-H1648 GDSC1 3.3926 5.6792 0.5638 1.7185
NCI-H211 GDSC1; CTRP2 3.4088 5.8045 3.0065 12.3598
NCI-H2818 GDSC1 3.4343 5.7544 0.5529 1.7255
NCI-H1105 GDSC1; CTRP2 3.4348 5.1023 3.2716 11.2962
LB647-SCLC GDSC1 3.4354 5.3636 0.7078 0.9807
NCI-H69 GDSC1; CTRP2 3.4411 6.1309 2.9127 12.6297
HOP-62 GDSC1; CTRP2 3.4595 6.0343 2.971 12.3546
NCI-H1734 GDSC1; CTRP2 3.4815 5.2036 3.2928 11.0785
SK-MES-1 GDSC1; CTRP2 3.5186 4.9848 3.3951 10.5955
COR-L311 GDSC1 3.5208 5.4517 0.7104 0.8976
EBC-1 GDSC1; CTRP2 3.5239 4.9221 3.4167 10.5017
NCI-H1694 GDSC1; CTRP2 3.534 5.3614 3.2997 10.8979
NCI-H2461 GDSC1 3.5431 6.0473 0.4854 1.9493
PaCa-3 GDSC1 3.5515 5.5749 0.6763 1.0149
NCI-H2722 GDSC1 3.5665 5.3471 0.7683 0.6416
NCI-H2171 GDSC1 3.5751 5.1031 0.86 0.3504
NCI-H1876 GDSC1 3.5764 5.401 0.7524 0.6925
NCI-H2373 GDSC1 3.5799 5.5312 0.705 0.8722
NCI-H596 GDSC1 3.5975 5.2286 0.8237 0.4425
CPC-N GDSC1 3.6365 5.3906 0.7802 0.5577
HCC1588 CTRP2 3.6468 5.311 3.4388 10.0511
DMS 79 CTRP2 3.6925 6.3324 3.0914 11.2564
NCI-H2804 GDSC1 3.7103 6.5223 0.3712 2.3544
SBC-1 GDSC1 3.7241 5.4428 0.7953 0.4625
Ms-1 GDSC1 3.7324 5.3305 0.8383 0.3402
MOR/CPR CTRP2 3.7352 4.9389 3.643 9.042
NCI-H2795 GDSC1 3.7486 5.9316 0.6238 1.0697
DMS 454 CTRP2 3.7625 10.5458 1.1639 18.7267
Lu-139 GDSC1 3.7893 5.4367 0.822 0.3582
NCI-H146 GDSC1 3.7912 5.5978 0.7652 0.5184
RERF-LC-Sq1 GDSC1 3.7925 8.6443 -0.5133 7.6643
NCI-H64 GDSC1 3.8001 4.8786 1.0142 0.0421
Lu-99A GDSC1 3.8003 5.7522 0.7125 0.6871
Lu-135 GDSC1 3.8108 5.5528 0.7889 0.4383
NCI-H1437 GDSC1 3.8166 5.7302 0.727 0.627
NCI-H2066 GDSC1 3.8506 5.4922 0.8252 0.3256
NCI-H2087 GDSC1; CTRP2 3.8562 6.2168 3.3106 9.9618
NCI-H1915 GDSC1; CTRP2 3.8576 7.644 2.6593 12.575
IST-SL1 GDSC1 3.8616 5.7356 0.7427 0.5504
NCI-H835 GDSC1 3.9279 5.6203 0.8087 0.3357
NCI-H2810 GDSC1 3.9912 6.3161 0.5797 1.0526
SW1271 GDSC1; CTRP2 3.9979 5.9956 3.5522 8.6367
NCI-H1435 GDSC1; CTRP2 4.0066 5.4928 3.764 7.794
NCI-H1770 GDSC1 4.011 5.4579 0.8939 0.1448
Lu-65 GDSC1; CTRP2 4.0255 5.3949 3.8203 7.5274
HOP-92 CTRP2 4.0627 7.2653 3.038 10.5406
NCI-H2591 GDSC1 4.128 7.1499 0.3141 2.144
LC-2/ad GDSC1 4.1285 6.0172 0.7434 0.4187
DV-90 CTRP2 4.1637 5.7234 3.8397 7.0685
BEN GDSC1; CTRP2 4.1835 5.0461 4.1044 6.0122
NCI-H2106 CTRP2 4.1849 6.4067 3.5602 8.1234
NCI-H1341 GDSC1; CTRP2 4.1854 5.8071 3.8273 7.0588
NCI-H2029 GDSC1; CTRP2 4.1944 5.1894 4.0735 6.0926
NCI-H292 GDSC1; CTRP2 4.1977 7.014 3.2882 9.1967
NCI-H524 GDSC1 4.2078 5.6876 0.8845 0.1211
LXF 289 GDSC1; CTRP2 4.2115 5.9335 3.7998 7.0984
COLO 668 GDSC1; CTRP2 4.2151 5.5962 3.9459 6.5172
NCI-H1693 CTRP2 4.2311 5.3075 4.0733 5.9861
NCI-H23 GDSC1; CTRP2 4.2542 6.0997 3.7696 7.1083
NCI-H727 GDSC1; CTRP2 4.261 6.2135 3.7249 7.2702
LK2 CTRP2 4.2684 19.7881 -2.9837 29.3851
NCI-H513 GDSC1 4.2684 7.1051 0.3953 1.605
Calu-6 GDSC1; CTRP2 4.287 5.9968 3.849 6.7076
IST-SL2 GDSC1 4.2908 6.6173 0.5896 0.8028
DMS 114 GDSC1; CTRP2 4.2929 5.57 4.0386 5.9458
HCC44 GDSC1; CTRP2 4.3038 6.0462 3.8438 6.6854
NCI-H1993 GDSC1 4.3084 6.1043 0.7786 0.2721
SK-LU-1 GDSC1; CTRP2 4.3214 6.0444 3.8624 6.5663
NCI-H841 GDSC1; CTRP2 4.3325 6.1652 3.8185 6.7147
NCI-H2342 GDSC1; CTRP2 4.3377 7.2912 3.2888 8.867
NCI-H1573 GDSC1; CTRP2 4.3437 5.7618 4.0107 5.919
LUDLU-1 CTRP2 4.3485 5.6987 4.0429 5.7794
ABC-1 GDSC1 4.3765 6.3418 0.721 0.3754
NCI-H1092 GDSC1; CTRP2 4.3801 5.9059 3.9843 5.9295
COLO 699 CTRP2 4.3813 6.3432 3.7842 6.7332
NCI-H647 GDSC1; CTRP2 4.3885 5.3563 4.2245 4.9667
DMS 273 GDSC1; CTRP2 4.3899 5.4231 4.2001 5.0556
NCI-H2110 GDSC1; CTRP2 4.3981 5.5843 4.1429 5.2553
EMC-BAC-2 GDSC1 4.402 6.2518 0.7614 0.2787
NCI-H2291 GDSC1; CTRP2 4.4128 6.4342 3.7721 6.7065
NCI-H520 GDSC1; CTRP2 4.4262 5.563 4.1812 5.0303
EKVX GDSC1; CTRP2 4.4383 6.6855 3.6767 7.0366
COR-L95 GDSC1; CTRP2 4.451 5.0969 4.3818 4.1973
NCI-H522 GDSC1; CTRP2 4.4544 5.2342 4.3403 4.3412
NCI-H209 GDSC1 4.4569 6.4675 0.7066 0.3796
RERF-LC-MS GDSC1; CTRP2 4.4625 6.2598 3.903 6.0531
NCI-H526 GDSC1; CTRP2 4.4647 5.937 4.0553 5.4308
NCI-H2405 GDSC1; CTRP2 4.4905 5.449 4.296 4.4094
NCI-H3122 GDSC1 4.4948 6.3973 0.7445 0.2847
NCI-H2731 GDSC1 4.5362 6.5808 0.696 0.3753
NCI-H322 CTRP2 4.5373 5.7159 4.2288 4.5516
NCI-H2122 GDSC1; CTRP2 4.5398 5.4098 4.3639 4.0123
NCI-H1155 GDSC1; CTRP2 4.5434 5.6147 4.2802 4.3312
Sq-1 CTRP2 4.5472 11.0573 1.6142 15.2607
NCI-H1355 GDSC1; CTRP2 4.5544 7.3522 3.4604 7.6685
Lu-134-A GDSC1 4.5584 6.358 0.7803 0.2031
NCI-H446 GDSC1; CTRP2 4.5656 5.2524 4.4533 3.5974
NCI-H2347 GDSC1 4.5665 6.5684 0.7113 0.331
NCI-H1184 CTRP2 4.5725 5.575 4.3275 4.0681
LC-1/sq-SF CTRP2 4.5743 5.0133 4.5395 3.253
NCI-H2228 GDSC1; CTRP2 4.5768 5.5046 4.3626 3.9183
NCI-H1373 CTRP2 4.5768 6.3051 3.9918 5.4184
NCI-H2196 GDSC1; CTRP2 4.5832 5.2064 4.4891 3.4119
ChaGo-K-1 GDSC1; CTRP2 4.5841 5.6103 4.3237 4.0536
NCI-H2023 GDSC1; CTRP2 4.5917 5.6475 4.3148 4.0694
A-549 GDSC1; CTRP2 4.618 6.2865 4.0401 5.1235
NCI-H1339 CTRP2 4.6292 5.3343 4.4889 3.2838
SW1573 GDSC1 4.6438 10.3699 -0.7954 7.698
NCI-H838 GDSC1; CTRP2 4.6477 6.2559 4.0829 4.8784
NCI-H1581 GDSC1; CTRP2 4.6505 5.7347 4.3338 3.8456
NCI-H2869 GDSC1 4.6578 6.5739 0.7418 0.2445
HCC78 GDSC1; CTRP2 4.6705 6.8229 3.8271 5.8873
NCI-H2595 GDSC1 4.7231 6.5862 0.7604 0.198
NCI-H1755 GDSC1; CTRP2 4.7257 6.5601 4.007 5.0172
VMRC-LCD CTRP2 4.729 5.5326 4.5052 2.9591
NCI-H1838 GDSC1; CTRP2 4.7478 5.5054 4.5364 2.7862
EMC-BAC-1 GDSC1 4.7539 6.7365 0.7203 0.2582
HCC2935 CTRP2 4.7743 7.7379 3.4664 7.1732
SHP-77 GDSC1; CTRP2 4.7979 6.6061 4.0497 4.6823
T3M-10 CTRP2 4.8134 5.7298 4.4943 2.8006
EPLC-272H GDSC1; CTRP2 4.8152 5.7266 4.4975 2.7829
RERF-LC-Ad2 CTRP2 4.8244 5.4378 4.6438 2.1626
NCI-H2170 GDSC1; CTRP2 4.8305 5.5534 4.5953 2.3458
NCI-H1651 GDSC1; CTRP2 4.8405 7.635 3.5754 6.5797
NCI-H1792 GDSC1; CTRP2 4.8444 8.4456 3.1744 8.2536
IA-LM GDSC1; CTRP2 4.8639 5.5416 4.633 2.1122
NCI-H2126 CTRP2 4.8746 7.6989 3.5731 6.5201
NCI-H661 GDSC1; CTRP2 4.8803 6.7337 4.0593 4.4686
NCI-H1299 GDSC1; CTRP2 4.9071 6.1148 4.3908 3.0242
NCI-H1623 GDSC1; CTRP2 4.9098 6.1086 4.3963 2.9957
NCI-H2009 GDSC1; CTRP2 4.9111 7.0955 3.9058 5.0498
PC-14 GDSC1; CTRP2 4.9426 6.6737 4.1434 3.9883
HCC15 GDSC1; CTRP2 4.9466 6.4141 4.2765 3.4216
Lu-99 CTRP2 4.949 6.0707 4.4497 2.6902
NCI-H2444 GDSC1; CTRP2 4.9606 5.8775 4.5561 2.3784
CAL-12T GDSC1; CTRP2 4.9622 6.5113 4.2414 3.5376
COR-L105 GDSC1; CTRP2 4.964 6.3286 4.3342 3.1442
LOU-NH91 GDSC1; CTRP2 4.9757 5.8644 4.5758 2.1063
KNS-62 GDSC1; CTRP2 4.9846 5.9052 4.5632 2.141
NCI-H1869 GDSC1; CTRP2 5.0028 6.3298 4.3667 2.9297
HCC1833 CTRP2 5.0112 7.9844 3.5466 6.36
HCC1438 CTRP2 5.02 6.8411 4.1256 3.9093
NCI-H2172 GDSC1; CTRP2 5.0373 5.9786 4.5713 2.0022
NCI-H650 GDSC1; CTRP2 5.0677 7.2774 3.9473 4.5667
NCI-H1793 GDSC1; CTRP2 5.095 6.4061 4.4052 2.5904
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 5.1396 6.4882 4.4003 2.5293
LCLC-103H GDSC1; CTRP2 5.142 7.8304 3.7319 5.3313
NCI-H1395 CTRP2 5.1451 7.0698 4.1143 3.7194
HCC4006 CTRP2 5.1583 6.2474 4.535 1.9313
HCC366 CTRP2 5.1757 7.423 3.9627 4.2996
RERF-LC-Ad1 CTRP2 5.2043 8.5036 3.4462 6.4152
Calu-1 CTRP2 5.2284 6.2592 4.5827 1.6131
NCI-H2085 CTRP2 5.3667 7.3463 4.1497 3.1826
HCC2279 CTRP2 5.3832 14.0396 0.826 16.5604
RERF-LC-A1 CTRP2 5.3904 9.6809 3.0078 7.9109
HCC827 GDSC1; CTRP2 5.4555 8.5679 3.6125 5.2705
HCC2108 CTRP2 5.4585 15.9096 -0.0471 19.4014
NCI-H1650 GDSC1; CTRP2 5.6097 8.5568 3.7342 4.5074
NCI-H226 GDSC1; CTRP2 5.7502 7.5527 4.3184 1.928
NCI-H441 GDSC1; CTRP2 5.8078 8.2073 4.045 2.9358
NCI-H196 GDSC1; CTRP2 5.8271 9.6441 3.3598 5.7047
NCI-H358 GDSC1; CTRP2 5.9283 9.3732 3.5651 4.7048
NCI-H1563 GDSC1; CTRP2 6.1519 12.5024 2.1934 9.9358
NCI-H2030 GDSC1; CTRP2 6.209 9.7402 3.5818 4.2294
SBC-5 GDSC1; CTRP2 6.2925 8.7835 4.0842 2.1685
NCI-H1975 GDSC1; CTRP2 6.4136 9.4188 3.8657 2.8516
NCI-H460 GDSC1; CTRP2 6.5466 9.3853 3.9613 2.3412
HCC1171 CTRP2 6.9917 16.8745 0.6633 14.2977
NCI-H2286 CTRP2 7.5716 17.1608 0.9413 12.4188
HCC1195 CTRP2 8.0944 13.7376 2.8997 4.5393
Hs 888.Lu CTRP2 4.2956 5.3719 4.1192 5.6289
⏷ Show the Full List of 211 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 3.2515 7.1086 -0.136 6.3388
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.7098 5.6173 3.3993 10.0175
ES-2 GDSC1 2.9766 4.7246 0.7544 1.2192
COV434 CTRP2 3.1696 5.4039 2.89 13.4856
OVKATE GDSC1 3.3083 4.9764 0.8015 0.6988
COV644 CTRP2 3.8258 7.013 2.923 11.5855
OAW28 GDSC1; CTRP2 3.8656 5.8074 3.4916 9.2302
JHOS-4 GDSC1 4.0939 5.9878 0.7409 0.4406
OAW42 GDSC1; CTRP2 4.1058 5.2368 3.9617 6.7663
OVCAR-3 GDSC1 4.1174 5.6304 0.8726 0.1547
A2780 GDSC1; CTRP2 4.1697 5.8566 3.7899 7.2473
COV362 CTRP2 4.4189 5.6868 4.1207 5.2872
OV7 CTRP2 4.4315 5.7175 4.1203 5.2561
OVCAR-5 GDSC1; CTRP2 4.4452 7.0195 3.5218 7.6591
TYK-nu GDSC1; CTRP2 4.4488 5.2119 4.342 4.3507
OVK18 GDSC1; CTRP2 4.4507 5.0234 4.4021 4.1245
JHOS-2 GDSC1; CTRP2 4.5148 5.1285 4.4415 3.7883
OC 314 GDSC1; CTRP2 4.529 5.2868 4.4011 3.8988
MCAS CTRP2 4.5627 6.2023 4.0275 5.3047
Caov-3 GDSC1; CTRP2 4.5828 5.1766 4.4992 3.3752
SNU-8 CTRP2 4.5865 5.2458 4.4782 3.4437
OVTOKO GDSC1; CTRP2 4.6301 6.0198 4.1796 4.5226
Caov-4 GDSC1 4.6442 6.773 0.6685 0.3999
DOV13 GDSC1; CTRP2 4.7124 6.4372 4.055 4.8472
OV-90 GDSC1; CTRP2 4.7481 5.5341 4.5235 2.8377
ONCO-DG-1 CTRP2 4.7565 5.4993 4.5479 2.7186
IGROV-1 GDSC1; CTRP2 4.7701 6.5249 4.0647 4.6798
RMG-I GDSC1; CTRP2 4.8289 6.3551 4.2018 3.9807
TOV-112D GDSC1; CTRP2 4.8472 6.2094 4.2904 3.5715
SNU-119 CTRP2 4.853 7.7053 3.5512 6.6558
SK-OV-3 GDSC1; CTRP2 4.922 5.8358 4.5426 2.358
OV56 GDSC1; CTRP2 4.9261 5.6796 4.6235 2.0113
TOV-21G GDSC1; CTRP2 4.9587 5.8871 4.5497 2.2512
EFO-21 GDSC1; CTRP2 5.0037 5.828 4.6182 1.8715
OVCAR-4 GDSC1; CTRP2 5.0469 6.4676 4.3348 2.9777
SNU-840 CTRP2 5.0564 7.8561 3.6485 5.8441
OVCAR-8 GDSC1; CTRP2 5.075 6.7613 4.2113 3.4433
OVSAHO CTRP2 5.0822 6.1203 4.5376 2.0585
Kuramochi GDSC1; CTRP2 5.1228 8.2253 3.5188 6.2627
ES2 CTRP2 5.2239 6.4048 4.5074 1.9338
EFO-27 GDSC1; CTRP2 5.2404 6.5388 4.4535 2.1301
FU-OV-1 GDSC1; CTRP2 5.2439 7.9172 3.7707 4.9811
JHOC-5 CTRP2 5.2489 6.0674 4.6917 1.1314
OVISE GDSC1; CTRP2 5.3344 6.6853 4.4513 1.986
HEY A8 CTRP2 5.4185 7.0453 4.336 2.3284
JHOM-1 CTRP2 6.7248 8.343 4.4972 0.4771
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 3.8563 7.0915 2.917 11.5339
P-STS CTRP2 4.6393 5.2703 4.5251 3.1166
H-STS CTRP2 4.6413 5.0133 4.6126 2.7854
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 4.5134 5.2196 4.4092 3.9128
SW684 GDSC1 2.0322 5.0718 0.0272 8.2393
Hs 633.T GDSC1 2.5887 4.1866 0.7882 1.5326
Tm87-16 CTRP2 3.2352 8.4395 1.6756 18.0285
BT-16 CTRP2 3.3061 5.4973 3.0068 12.6524
GCT GDSC1; CTRP2 3.3073 6.0973 2.7847 13.4912
MFH-ino GDSC1 3.4781 5.2164 0.7812 0.6543
RD GDSC1; CTRP2 3.5403 5.9862 3.0758 11.7278
TE 617.T CTRP2 3.5488 5.747 3.1781 11.3127
EW-8 GDSC1 3.6196 5.1456 0.8615 0.3274
VA-ES-BJ GDSC1 3.6406 5.1618 0.8636 0.3136
G-401 GDSC1; CTRP2 3.7285 6.7679 2.9367 11.7761
TTC-709 CTRP2 3.7548 5.6358 3.4407 9.7333
Rh41 GDSC1; CTRP2 3.7677 7.4518 2.6618 12.7831
SW982 GDSC1; CTRP2 3.8823 6.8404 3.0587 10.8982
A-204 GDSC1; CTRP2 3.8832 5.7456 3.5348 9.0149
SW872 GDSC1 3.9101 5.7206 0.7666 0.454
TE 441.T CTRP2 3.9244 5.2714 3.7534 8.0706
Rh30 GDSC1 3.9648 5.5906 0.8324 0.2683
Rh18 GDSC1; CTRP2 3.9853 5.5939 3.7029 8.0866
BT-12 CTRP2 4.115 5.6559 3.816 7.2931
HT-1080 GDSC1; CTRP2 4.3222 4.9688 4.2755 4.9731
KYM-1 GDSC1; CTRP2 4.3546 5.4539 4.1505 5.3445
MES-SA GDSC1; CTRP2 4.484 4.9138 4.4629 3.8055
SK-LMS-1 GDSC1; CTRP2 4.613 6.0966 4.1265 4.7805
SK-UT-1 GDSC1; CTRP2 4.6787 5.6978 4.3788 3.594
RKN GDSC1; CTRP2 5.0418 5.7161 4.7064 1.4255
G-402 GDSC1; CTRP2 5.0798 11.536 1.8281 13.3345
Hs 729.T CTRP2 5.362 9.3073 3.1715 7.2781
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.6839 5.2649 4.5747 2.8026
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1; CTRP2 3.6172 5.9182 3.1843 11.0981
IST-Mes1 GDSC1; CTRP2 3.9488 7.7897 2.6782 12.2801
NCI-H28 GDSC1; CTRP2 4.0255 7.0564 3.1004 10.3764
MSTO-211H GDSC1; CTRP2 4.6646 6.9319 3.768 6.146
NCI-H2452 GDSC1; CTRP2 4.7312 7.3461 3.6231 6.6075
NCI-H2052 GDSC1; CTRP2 5.249 6.6822 4.3891 2.3841
ACC-MESO-1 CTRP2 5.3887 8.2236 3.7318 4.8873
JL-1 CTRP2 9.4053 21.4225 0.1423 12.5116
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 3.7992 5.7933 0.6968 0.7435
22Rv1 GDSC1; CTRP2 4.1682 6.4959 3.5025 8.3977
VCaP GDSC1; CTRP2 4.3259 5.1582 4.2264 5.1398
LNCaP clone FGC GDSC1; CTRP2 4.5261 5.8156 4.1724 4.8061
NCI-H660 CTRP2 4.6345 7.2464 3.5856 6.9715
PaCa-3 CTRP2 5.299 6.295 4.6165 1.3627
DU145 GDSC1; CTRP2 5.4455 7.5257 4.1201 3.1761
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 4.1429 5.8674 3.7575 7.4458
A-253 GDSC1; CTRP2 4.7344 6.2306 4.1766 4.2934
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 3.3769 4.9933 0.823 0.5715
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 GDSC1; CTRP2 1.0153 3.435 0.96 27.0285
HSC-39 GDSC1 1.5567 3.6915 0.3511 7.2263
SNU-620 CTRP2 1.8495 3.2833 1.8398 21.3174
GSS CTRP2 2.4227 4.1821 2.3643 17.664
Fu97 GDSC1; CTRP2 2.679 4.7921 2.5272 16.2841
SCH GDSC1 3.2948 4.6642 0.9104 0.3397
RF-48 GDSC1 3.3077 5.3967 0.638 1.4353
IM95 GDSC1; CTRP2 3.623 5.5535 3.3295 10.5285
TGBC11TKB GDSC1 3.7134 5.7408 0.6814 0.8631
SNU-1 GDSC1; CTRP2 3.9791 5.5523 3.7123 8.0683
SNU-601 CTRP2 4.0298 5.6145 3.7422 7.8122
HuG1-N CTRP2 4.0428 7.1797 3.0592 10.5023
HGC-27 GDSC1; CTRP2 4.1088 6.3354 3.5163 8.4913
Hs 746.T GDSC1; CTRP2 4.1445 6.4037 3.5211 8.3819
KE-39 CTRP2 4.1484 7.9244 2.8032 11.3024
23132/87 GDSC1; CTRP2 4.2089 5.2652 4.064 6.0849
NUGC-3 GDSC1; CTRP2 4.3282 5.2806 4.1876 5.2778
OCUM-1 GDSC1 4.3346 6.6883 0.5809 0.8051
AGS GDSC1; CTRP2 4.35 5.6942 4.0463 5.762
GCIY GDSC1 4.4068 6.0699 0.8248 0.1666
SNU-216 CTRP2 4.4788 5.449 4.2837 4.4891
SNU-668 CTRP2 4.5116 5.8785 4.1291 5.0167
GSU CTRP2 4.5445 4.9055 4.5295 3.3813
KATO III GDSC1; CTRP2 4.5628 5.6596 4.28 4.2819
ECC10 GDSC1; CTRP2 4.591 5.3148 4.4564 3.5145
NCI-N87 GDSC1 4.6125 6.7727 0.6569 0.4397
MKN74 CTRP2 4.6628 6.8364 3.8134 5.9611
MKN28 GDSC1 4.7191 6.8633 0.6643 0.3826
RERF-GC-1B GDSC1 4.8006 7.2593 0.5551 0.6291
SH-10-TC CTRP2 4.9209 5.7373 4.5903 2.1614
NUGC-4 GDSC1; CTRP2 4.9442 5.9359 4.5126 2.4364
SNU-719 CTRP2 4.9552 8.4836 3.2499 7.7157
LMSU CTRP2 5.2479 6.9842 4.2385 3.0146
ECC12 CTRP2 5.484 7.9463 3.9415 3.8533
MKN7 GDSC1; CTRP2 5.4912 7.213 4.3061 2.3396
MKN45 GDSC1; CTRP2 6.1552 7.2515 4.6723 0.3407
SNU-5 GDSC1; CTRP2 6.8606 8.3716 4.5436 0.3155
MKN1 GDSC1; CTRP2 9.3079 24.0618 -1.1883 16.5569
SNG-M GDSC1; CTRP2 4.6499 6.5046 3.9641 5.3642
SNU-685 CTRP2 4.6604 5.1039 4.6077 2.7452
SNU-1077 CTRP2 5.24 7.4066 4.0221 3.9339
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1 2.999 4.7001 0.7745 1.095
ASH-3 GDSC1 3.0102 4.7815 0.7471 1.2184
WRO GDSC1 3.1153 4.6845 0.8314 0.7295
K5 GDSC1 3.1687 5.1685 0.6652 1.4554
KMH-2 GDSC1 3.5909 5.7755 0.6158 1.2476
BHT-101 GDSC1; CTRP2 3.699 5.1081 3.5583 9.4574
SW579 CTRP2 3.8022 4.8986 3.7256 8.5403
TT GDSC1; CTRP2 4.11 5.4256 3.9 6.9856
HTC-C3 GDSC1 4.1376 6.0843 0.7231 0.4694
8305C GDSC1; CTRP2 4.3445 5.3707 4.172 5.2904
B-CPAP GDSC1; CTRP2 4.3557 5.0214 4.299 4.7857
8505C GDSC1; CTRP2 4.37 5.9152 3.9699 6.0128
FTC-238 CTRP2 4.5065 5.0985 4.4417 3.8122
CAL-62 GDSC1; CTRP2 4.6327 5.7754 4.2972 4.0378
CGTH-W-1 GDSC1; CTRP2 4.8743 6.6411 4.1002 4.3099
ML-1 [Human leukemia] GDSC1; CTRP2 5.0506 6.1982 4.4726 2.3913
TT2609-C02 GDSC1; CTRP2 5.4692 7.1507 4.3208 2.3128
FTC-133 GDSC1; CTRP2 6.5646 7.9887 4.5648 0.3949
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 16 CTRP2 2.6819 13.0405 -1.0601 28.5383
Detroit 562 GDSC1; CTRP2 2.9413 4.4618 2.878 14.2266
KON GDSC1 2.9999 5.2905 0.531 2.4465
OSC-20 GDSC1 3.357 5.1794 0.7449 0.8896
BB49-HNC GDSC1 3.4189 5.4526 0.6661 1.1828
SCC-25 GDSC1; CTRP2 3.4703 6.3366 2.8585 12.7612
HO-1-u-1 GDSC1 3.4886 5.4262 0.7065 0.9405
SKN-3 GDSC1 3.5898 5.194 0.8332 0.4183
OSC-19 GDSC1 3.6263 5.2791 0.8166 0.4489
BHY GDSC1; CTRP2 3.631 5.3745 3.4007 10.2389
BB30-HNC GDSC1 3.6346 5.7777 0.634 1.1252
CAL-33 GDSC1; CTRP2 3.6383 5.4233 3.392 10.25
SAS GDSC1 3.6514 6.4436 0.375 2.4112
PCI-38 GDSC1 3.7078 6.1599 0.5167 1.5992
HO-1-N-1 GDSC1 3.7556 5.386 0.8273 0.3585
YD-10B CTRP2 3.7781 5.3906 3.5545 9.2373
JHU-011 GDSC1 3.8174 5.6681 0.75 0.5518
SCC-15 GDSC1 3.8192 5.8213 0.6945 0.7386
PCI-15A GDSC1 3.8342 5.4556 0.8319 0.3156
KOSC-2 GDSC1 3.8639 6.2591 0.5472 1.3005
BICR 10 GDSC1 3.8744 5.6876 0.7649 0.4765
BICR 22 GDSC1; CTRP2 3.9019 5.0789 3.7879 8.0115
PCI-30 GDSC1 3.9515 5.601 0.824 0.2913
LB771-HNC GDSC1 4.0242 6.1473 0.6563 0.7402
PCI-06A GDSC1 4.0259 5.8541 0.7627 0.4121
NCI-H3118 GDSC1 4.0848 6.1449 0.6811 0.6213
SNU-899 CTRP2 4.1602 5.4444 3.9468 6.666
HSC-3 GDSC1; CTRP2 4.1625 5.1073 4.0641 6.2217
JHU-022 GDSC1 4.1874 6.1747 0.7097 0.4835
PE/CA-PJ49 CTRP2 4.2 5.3115 4.0382 6.2073
SCC-9 GDSC1; CTRP2 4.2641 5.7379 3.9385 6.4133
CAL-27 GDSC1; CTRP2 4.2742 5.3177 4.1161 5.7015
BICR 78 GDSC1 4.3056 6.2369 0.7317 0.3767
DOK GDSC1 4.4029 6.335 0.733 0.3386
BICR 18 CTRP2 4.4332 5.3095 4.29 4.5912
SNU-1066 CTRP2 4.4525 6.1834 3.929 5.9714
PCI-04B GDSC1 4.505 6.0758 0.8562 0.1086
SNU-1076 CTRP2 4.5277 5.7535 4.2023 4.6823
YD-8 CTRP2 4.5307 11.0378 1.6095 15.3143
Ca9-22 GDSC1 4.5665 6.5741 0.7093 0.3352
BICR 31 GDSC1; CTRP2 4.5673 5.7031 4.265 4.3304
PE/CA-PJ15 GDSC1; CTRP2 4.5708 5.7935 4.2272 4.4735
PE/CA-PJ34 (clone C12) CTRP2 4.6107 5.4757 4.4101 3.6419
BICR 6 CTRP2 4.6931 5.1136 4.6401 2.5291
FaDu GDSC1; CTRP2 4.7083 5.3552 4.5629 2.7828
HSC-2 GDSC1; CTRP2 4.7502 6.4435 4.0867 4.632
PE/CA-PJ41 (clone D2) CTRP2 5.0277 6.0215 4.5418 2.145
SAT [Human HNSCC] GDSC1 5.0966 7.6721 0.5198 0.5898
HSC-4 GDSC1; CTRP2 5.1734 6.2807 4.5302 1.9247
BICR 56 CTRP2 5.2531 6.3565 4.5531 1.6953
SNU-1041 CTRP2 5.6585 8.009 4.0375 3.1838
SNU-46 CTRP2 6.1775 10.9224 2.9878 6.6794
SCC-4 GDSC1; CTRP2 6.3456 8.2876 4.3358 1.2162
SNU-1214 CTRP2 7.3041 9.4366 4.3255 0.6014
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-BLC1 CTRP2 0.6769 4.8281 0.3353 30.2414
CAL-29 GDSC1; CTRP2 2.9458 4.5946 2.8594 14.277
BFTC-905 GDSC1; CTRP2 3.4603 4.8495 3.3647 10.8842
SW780 GDSC1 3.6018 5.0686 0.882 0.2839
253J CTRP2 3.8894 4.7131 3.8564 7.807
253J-BV CTRP2 3.9345 6.898 3.0843 10.6653
647V GDSC1; CTRP2 4.1221 5.5367 3.8708 7.0625
JMSU-1 CTRP2 4.1431 6.0593 3.6745 7.7727
UM-UC-1 CTRP2 4.2503 5.5545 3.9999 6.2117
RT-4 GDSC1; CTRP2 4.3237 8.4777 2.6955 11.3516
VM-CUB-1 CTRP2 4.3449 7.7947 3.0502 9.8368
RT-112 GDSC1; CTRP2 4.4054 5.1713 4.3086 4.6017
TCCSUP GDSC1; CTRP2 4.4794 5.0325 4.431 3.9329
639V GDSC1; CTRP2 4.4959 5.074 4.4375 3.8593
BC-3C CTRP2 4.5069 5.2257 4.3999 3.9665
HT-1197 GDSC1; CTRP2 4.5381 6.6811 3.7735 6.4069
UM-UC-3 GDSC1; CTRP2 4.558 5.0075 4.5232 3.3614
J82 GDSC1; CTRP2 4.6377 6.3416 4.032 5.1116
SW1710 GDSC1; CTRP2 4.8128 6.6929 4.02 4.7751
KMBC-2 CTRP2 5.0279 7.5438 3.7809 5.3427
T24 GDSC1; CTRP2 5.0291 6.7649 4.1714 3.6991
KU-19-19 GDSC1; CTRP2 5.2481 6.6893 4.3849 2.4027
HT-1376 GDSC1; CTRP2 5.6927 8.3509 3.8954 3.7128
SCaBER CTRP2 5.7894 10.0685 2.3684 4.8292
5637 GDSC1; CTRP2 6.2452 11.1566 2.922 6.8427
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
C-4-I GDSC1 2.6112 4.4259 0.6979 2.0428
NEC8 GDSC1 2.7127 4.7511 0.6114 2.416
SW954 GDSC1 2.7946 4.8085 0.6301 2.1661
HEC-1 GDSC1 2.8051 5.388 0.3813 3.7546
NT2-D1 GDSC1 2.9162 4.758 0.7124 1.5142
JHOS-3 GDSC1 2.9463 7.3691 -0.4508 9.2021
SW756 GDSC1 2.9504 4.9058 0.668 1.7152
PA-1 GDSC1 3.3112 5.2294 0.7057 1.1045
SW962 GDSC1 3.3124 4.9193 0.8245 0.6091
OMC-1 [Human cervical carcinoma] GDSC1 3.3545 5.0083 0.8084 0.6393
PWR-1E GDSC1 3.3718 5.2856 0.7104 1.0263
SiHa GDSC1 3.4085 5.0066 0.8306 0.5256
TC-YIK GDSC1 3.4417 5.619 0.6107 1.4241
HT-3 GDSC1 3.4553 5.8686 0.5165 1.8925
LB831-BLC GDSC1 3.4571 5.6249 0.6153 1.385
SKG-IIIa GDSC1 3.4573 4.7828 0.9288 0.2281
MS751 GDSC1 3.4668 5.3018 0.7446 0.8021
JEG-3 GDSC1 3.6164 5.0355 0.8988 0.2402
SKN GDSC1 3.6544 5.5338 0.7346 0.7042
OVCA420 GDSC1 3.663 5.2559 0.8387 0.3685
JAR GDSC1 3.6783 5.3054 0.8269 0.3939
SiSo GDSC1 3.7327 5.7889 0.6713 0.8882
DoTc2 4510 GDSC1 3.7772 5.7477 0.7049 0.7292
OV17R GDSC1 3.8264 6.1395 0.5772 1.2022
C-33 A GDSC1 3.8582 5.7513 0.7356 0.5746
DSH1 GDSC1 3.8731 5.5417 0.8161 0.339
CAL-39 GDSC1 3.9349 5.9773 0.6833 0.7032
KGN GDSC1 3.9937 6.455 0.5277 1.2688
NCC-IT GDSC1 4.0225 5.7198 0.8086 0.3012
HEY GDSC1 4.0643 6.2864 0.621 0.8399
OVCA433 GDSC1 4.1019 6.1477 0.6867 0.5942
ME-180 GDSC1 4.3013 6.9653 0.4635 1.2781
OVMIU GDSC1 4.3163 6.8197 0.5248 1.0213
BPH-1 GDSC1 4.3611 6.842 0.5348 0.9521
ACC-OV7 GDSC1 4.4462 7.0509 0.4915 1.0536
HeLa GDSC1; CTRP2 4.6619 5.3179 4.53 3.0359
PEO1 GDSC1 4.8447 6.6297 0.7875 0.1376
UWB1.289 GDSC1 4.8532 7.2643 0.5731 0.5548
Ca Ski GDSC1 4.9194 7.4595 0.5286 0.6473
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6623).
2 Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1. Biochem J. 2012 May 15;444(1):79-88.