Details of the Drug

General Information of Drug (ID: DMC83EU)

• Drug Name: Benznidazole
• Synonyms: BENZNIDAZOLE; Radanil; Benzonidazole; 22994-85-0; Benznidazol; benzonidazol; Benznidazolum;Ro 07-1051; Rochagan; UNII-YC42NRJ1ZD; Benznidazolum [INN-Latin]; Benznidazol [INN-Spanish]; Ro 71051; NSC 299972; Benznidazole [INN]; CCRIS 2200

Indication

Disease Entry	ICD 11	Status	REF
Chagas disease	IF53	Approved	[1]
Trypanosomiasis	1D51-1F53	Approved	[2]

• Affected Organisms: Trypanosoma cruzi
• ATC Code:
  P01CA02: Benznidazole
  P01CA: Nitroimidazole derivatives
  P01C: AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS
  P01: ANTIPROTOZOALS
  P: ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C12H12N4O3
  Canonical SMILES: C1=CC=C(C=C1)CNC(=O)CN2C=CN=C2[N+](=O)[O-]
  InChI: InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)
  InChIKey: CULUWZNBISUWAS-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 31593
  ChEBI ID: CHEMBL110
  CAS Number: 22994-85-0
  UNII: YC42NRJ1ZD
  DrugBank ID: DB11989
  TTD ID: D04XGT
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References

• [1] 2017 FDA drug approvals.Nat Rev Drug Discov. 2018 Feb;17(2):81-85.
• [2] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015