Details of the Drug

General Information of Drug (ID: DMC8NAO)

Drug Name
ADXS-HPV
Indication
Disease Entry ICD 11 Status REF
Cervical cancer 2C77.0 Phase 2 [1]
Cervical Intraepithelial neoplasia 2E66.1 Phase 2 [1]
Drug Type
Vaccine
Cross-matching ID
TTD ID
D04FFM
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Human papillomavirus protein E7 (HPV E7) TT3CPZW VE7_HPV16 Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT02002182) Window of Opportunity Trial of ADXS 11-001 Vaccination Prior to Robotic Surgery of HPV-Positive Oropharyngeal Cancer. U.S. National Institutes of Health.
2 ADXS11-001 immunotherapy targeting HPV-E7: updated survival and safety data from a phase 2 study in Indian women with recurrent/refractory cervical cancer. Journal for ImmunoTherapy of Cancer, 2013, 1(Suppl 1):P231.