Details of the Drug

General Information of Drug (ID: DMCE5DP)

Drug Name
Elesclomol
Synonyms
Elesclomol; 488832-69-5; Elesclomol (STA-4783); STA-4783; UNII-6UK191M53P; CHEBI:79369; 6UK191M53P; Propanedioic acid, bis[2-methyl-2-(phenylthioxomethyl)hydrazide]; 1,3-Bis[2-methyl-2-(phenylthioxomethyl)hydrazide]propanedioic acid; N'1,N'3-dimethyl-N'1,N'3-di(phenylcarbonothioyl)malonohydrazide; J-503879; C19H20N4O2S2; 1-N'-Benzenecarbothioyl-3-(2-benzenecarbothioyl-2-methylhydrazinyl)-N'-methyl-oxopropanehydrazidide; Elesclomol [USAN:INN]; elesclomolum
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Phase 3 [1]
Affected Organisms
Humans and other mammals
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C19H20N4O2S2
Canonical SMILES
CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2
InChI
1S/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25)
InChIKey
BKJIXTWSNXCKJH-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
300471
ChEBI ID
CHEBI:79369
CAS Number
488832-69-5
UNII
6UK191M53P
DrugBank ID
DB05719
TTD ID
D05IRV
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 -6.2023 -1.1738 -6.9177 48.9484
ES1 GDSC1 -9.5785 -7.143 -9.5816 85.0044
ES8 GDSC1 -9.0054 -6.5046 -9.0118 79.6923
EW-16 GDSC1 -8.6561 -6.4805 -8.6594 77.0869
HOS GDSC1 -8.3156 -7.369 -8.3156 74.8701
H-EMC-SS GDSC1 -8.097 -4.1534 -8.2353 67.3652
EW-11 GDSC1 -7.9201 -3.4435 -8.1658 64.728
NOS-1 [Human HNSCC] GDSC1 -7.7623 -4.2574 -7.8643 65.0008
ES4 GDSC1 -7.4932 -5.6621 -7.4966 64.3183
TC-71 GDSC1 -7.4354 -5.1211 -7.4516 63.1967
CHSA8926 GDSC1 -7.0378 -0.4929 -8.0626 55.2265
MHH-ES-1 GDSC1; GDSC2 -6.8059 -2.7007 -7.1174 45.6531
ES7 GDSC1 -6.7839 -4.249 -6.8312 55.417
EW-1 GDSC1 -6.5063 -2.1301 -6.9422 51.7582
SJSA-1 GDSC1 -6.3844 -4.8074 -6.3894 50.7754
SaOS-2 GDSC1 -6.367 -3.0016 -6.5712 50.4868
CAL-72 GDSC1 -6.2967 -2.2872 -6.6693 49.7485
A-673 GDSC1 -6.1111 -2.8544 -6.3249 47.6979
U2OS GDSC1; GDSC2 -6.0092 0.9619 -7.5507 41.5443
ES5 GDSC1; GDSC2 -5.5169 -1.5165 -6.0578 34.5384
EW-13 GDSC1 -5.2724 -2.579 -5.4755 37.9557
CADO-ES1 GDSC1 -5.1852 -1.518 -5.6981 38.3021
HuO-3N1 GDSC1 -5.0509 -3.1099 -5.1279 34.5753
HuO9 GDSC1 -5.0294 -1.7293 -5.4574 36.1632
SK-PN-DW GDSC1 -5.013 0.8959 -6.4952 39.791
CAL-78 GDSC1 -4.4914 1.9843 -6.4716 36.7635
EW-3 GDSC1 -4.1484 1.3181 -5.8225 32.5238
ES6 GDSC1 -4.0681 0.2767 -5.2598 29.3567
EW-22 GDSC1 -3.6499 -1.1567 -4.1977 20.3932
CHSA0011 GDSC1; GDSC2 -3.551 2.1805 -5.6647 24.1279
G-292 clone A141B1 GDSC1 -3.4508 0.0205 -4.5291 21.7253
NY GDSC1 -3.1891 0.7943 -4.6509 21.3303
EW-7 GDSC1 -3.0917 1.0919 -4.7063 21.2638
EW-12 GDSC2 -2.9174 0.1549 -4.0859 13.0127
EW-24 GDSC1 -2.1178 6.6035 -6.6157 27.2184
CHSA0108 GDSC1; GDSC2 -2.0601 2.5838 -4.5602 13.261
SK-ES-1 GDSC1 -1.8068 1.4881 -3.8165 9.9842
EW-18 GDSC1 -1.0419 4.5503 -4.7585 14.2277
U-CH2 GDSC2 -0.9909 4.3427 -4.6206 10.8794
MG-63 GDSC1 -0.0317 14.2231 -8.772 28.0505
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 164 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 -6.7964 -5.6048 -6.7967 44.9027
MOLT-16 GDSC1 -8.1875 -6.7186 -8.1877 72.9849
Karpas-231 GDSC1 -7.587 -6.9159 -7.587 65.8134
MLMA GDSC1 -7.5447 -4.2043 -7.6396 63.0512
SU-DHL-5 GDSC1 -7.4612 -6.5712 -7.4612 64.2368
NB4 GDSC1; GDSC2 -7.3941 -6.6695 -7.3941 50.8996
BL-41 GDSC1 -7.3836 -6.724 -7.3836 63.271
697 GDSC1 -7.308 -5.7828 -7.309 62.2202
TALL-1 [Human adult T-ALL] GDSC2 -7.1519 -4.9345 -7.1686 48.4913
CRO-AP2 GDSC1; GDSC2 -6.8122 -5.5365 -6.8127 45.0622
OCI-Ly7 GDSC1; GDSC2 -6.7688 -5.9135 -6.7688 44.6248
Namalwa GDSC1 -6.7395 -5.2288 -6.7418 55.1873
L-363 GDSC1 -6.7209 -4.3307 -6.7584 54.7363
KOPN-8 GDSC1 -6.7149 -5.2101 -6.7171 54.882
EJM GDSC1 -6.7002 -5.1888 -6.7025 54.6983
MOLM-16 GDSC1; GDSC2 -6.7002 -4.7991 -6.7111 43.978
Ramos.2G6.4C10 GDSC1 -6.6766 -4.6504 -6.6928 54.3162
MV4-11 GDSC1 -6.6704 -4.2291 -6.7139 54.1205
KMS-12-BM GDSC1 -6.5797 -5.1575 -6.5815 53.2089
RPMI-8866 GDSC1 -6.5412 -3.767 -6.6275 52.5185
SU-DHL-1 GDSC2 -6.5173 -3.5356 -6.6354 42.5138
GA-10 GDSC1 -6.5066 -5.4474 -6.5068 52.3072
HEL GDSC1; GDSC2 -6.4289 -3.9746 -6.484 41.4347
CTB-1 GDSC1; GDSC2 -6.243 -4.1077 -6.2768 39.5004
JJN-3 GDSC1 -6.1449 -4.9455 -6.1458 47.7895
OCI-Ly19 GDSC1; GDSC2 -6.1361 -5.053 -6.1365 38.2778
JURL-MK1 GDSC1 -6.0622 -3.6802 -6.129 46.9135
MHH-PREB-1 GDSC1 -6.0414 -3.6386 -6.112 46.6718
NCI-H929 GDSC1 -5.9993 -4.7485 -6.0011 45.9745
P12-Ichikawa GDSC1 -5.9577 -2.1434 -6.3399 46.2781
MM1.S GDSC1 -5.9255 -3.7761 -5.9734 45.212
JeKo-1 GDSC1; GDSC2 -5.918 -3.1912 -6.0479 36.6827
DND-41 GDSC1 -5.8946 -4.1356 -5.9128 44.7333
Farage GDSC1; GDSC2 -5.8159 -4.6865 -5.817 35.0679
SIG-M5 GDSC2 -5.7972 -4.0425 -5.8175 34.9749
JSC-1 GDSC1 -5.7927 -4.4297 -5.7973 43.4082
U266B1 GDSC1 -5.7703 -3.4146 -5.853 43.4409
MOLP-8 GDSC1 -5.7418 -4.6053 -5.7432 42.7561
Sc-1 GDSC1 -5.6131 -3.6585 -5.656 41.3556
NU-DUL-1 GDSC1; GDSC2 -5.5403 -4.4429 -5.5419 32.3048
WSU-DLCL2 GDSC1 -5.5152 -3.6624 -5.5526 40.1172
P32/ISH GDSC1 -5.4381 -4.3909 -5.4395 38.9605
ALL-SIL GDSC1 -5.3837 -3.4784 -5.4331 38.5492
GR-ST GDSC1 -5.3296 1.0452 -6.8848 42.6337
BV-173 GDSC1 -5.3239 -2.5881 -5.5294 38.5837
SU-DHL-6 GDSC1 -5.3087 -4.3009 -5.3101 37.3433
CCRF-CEM GDSC1 -5.1424 2.1683 -7.2015 42.129
SUP-M2 GDSC1 -5.0996 -3.4011 -5.141 34.9715
RPMI-8226 GDSC1 -5.0699 -1.9153 -5.4411 36.3622
U-698-M GDSC1 -5.052 -0.2608 -6.0382 38.6515
QIMR-WIL GDSC1; GDSC2 -4.9569 -1.9657 -5.3021 28.2214
Jiyoye GDSC1 -4.9478 -2.2145 -5.2177 34.3963
Reh GDSC1 -4.9471 -2.7456 -5.0833 33.6359
ALL-PO GDSC1 -4.914 1.5914 -6.7086 39.7672
RCH-ACV GDSC1; GDSC2 -4.8609 -2.4382 -5.0619 26.5201
L-540 GDSC1 -4.8469 -1.6614 -5.2825 34.078
EoL-1 GDSC1 -4.789 -0.4938 -5.666 35.5288
HAL-01 GDSC1 -4.7885 -1.0138 -5.4572 34.5754
MHH-CALL-4 GDSC2 -4.7675 -1.8754 -5.1249 26.4122
Karpas-1106P GDSC1 -4.6526 -1.812 -5.021 31.3992
KG-1 GDSC1 -4.6126 -0.6537 -5.4149 33.2739
VAL GDSC1 -4.5749 -2.2958 -4.7879 29.5111
RL GDSC1; GDSC2 -4.4538 -1.3504 -4.9709 24.1695
AMO1 GDSC1 -4.4279 1.3299 -6.1035 35.1584
SUP-B8 GDSC1; GDSC2 -4.3254 -0.9055 -5.0097 23.8195
Karpas-620 GDSC1 -4.2671 -0.8781 -4.9596 28.748
YT GDSC1 -4.2569 0.375 -5.4945 31.5979
MN-60 GDSC1 -4.2216 -0.6401 -5.0116 28.7985
HC-1 GDSC1 -4.1502 -1.393 -4.6301 26.0238
ATN-1 GDSC1 -4.1072 1.38 -5.8112 32.2588
NKM-1 GDSC1 -4.0916 2.5079 -6.3337 34.2471
WSU-NHL GDSC1 -4.0294 1.1159 -5.6108 30.9368
BONNA-12 GDSC2 -4.0111 -0.0505 -5.054 22.7478
JVM-3 GDSC1 -3.9557 1.6821 -5.8076 31.4647
SKM-1 GDSC1; GDSC2 -3.8711 4.2818 -6.9896 30.721
MY-M12 GDSC1; GDSC2 -3.8327 -0.2339 -4.791 20.5686
SR GDSC1 -3.7555 0.568 -5.0849 26.7464
TK [Human B-cell lymphoma] GDSC1 -3.6984 -1.5245 -4.0979 19.9381
WIL2 NS GDSC1 -3.6758 -1.5128 -4.0785 19.6814
KCL-22 GDSC1 -3.6196 -1.2332 -4.1338 19.7829
MOLT-4 GDSC1 -3.5966 0.3105 -4.8083 24.2717
ROS-50 GDSC1; GDSC2 -3.5913 -0.978 -4.2139 16.2587
Loucy GDSC1 -3.571 0.2405 -4.7502 23.7743
DG-75 GDSC1 -3.5549 -0.1297 -4.5611 22.446
Karpas-299 GDSC1 -3.4786 1.6085 -5.3183 26.7144
K-562 GDSC1 -3.4579 1.6076 -5.2985 26.5091
LAMA-84 GDSC1 -3.4162 5.6232 -7.2396 34.1379
NOMO-1 GDSC1 -3.4091 1.7333 -5.3141 26.3675
BC-1 GDSC1 -3.3595 -0.6833 -4.111 18.3295
KE-37 GDSC1 -3.3126 0.0009 -4.3854 20.077
DoHH2 GDSC1; GDSC2 -3.3041 2.2554 -5.473 22.284
SU-DHL-16 GDSC1; GDSC2 -3.2538 0.076 -4.3647 15.8858
Raji GDSC1 -3.2113 1.3887 -4.9622 23.4222
H9 GDSC1 -3.2073 -0.7567 -3.9257 16.2441
A4/Fukuda GDSC1 -3.0352 0.8162 -4.5189 19.755
KMOE-2 GDSC1 -3.0301 3.3238 -5.7547 26.959
KMS-11 GDSC1; GDSC2 -2.9937 2.274 -5.2012 19.7887
A3/Kawakami GDSC1 -2.9156 -0.8299 -3.6063 12.5011
BE-13 GDSC1 -2.9148 1.9361 -4.9632 22.1352
EB2 GDSC1 -2.7395 -0.353 -3.6728 12.2566
HT GDSC1; GDSC2 -2.7124 1.7642 -4.6988 16.0389
RPMI-8402 GDSC1 -2.6614 2.4849 -5.0137 21.4
HH [Human lymphoma] GDSC1 -2.5762 2.9366 -5.166 21.9688
MOLT-13 GDSC1 -2.5531 3.3946 -5.3751 23.0634
NK-92MI GDSC2 -2.5381 2.2191 -4.775 15.932
CTV-1 GDSC1 -2.5293 3.8698 -5.5923 24.1288
DEL GDSC1 -2.4755 7.1326 -7.1777 30.45
VL51 GDSC1 -2.4029 0.0614 -3.5818 10.2212
Karpas-45 GDSC1 -2.3933 2.5415 -4.8134 19.0987
DB GDSC1 -2.3923 2.7119 -4.8978 19.6303
PL-21 GDSC1; GDSC2 -2.3018 1.6936 -4.3129 12.4722
TUR GDSC1 -2.2071 2.5923 -4.684 17.5601
SU-DHL-4 GDSC1; GDSC2 -2.1822 1.7416 -4.2385 11.6718
HL-60 GDSC1 -2.1002 5.9199 -6.2596 25.6996
EHEB GDSC1 -2.0796 1.2167 -3.8936 11.4678
Karpas-422 GDSC1 -2.0368 2.9782 -4.7383 17.3023
RS4;11 GDSC1 -1.9217 5.9764 -6.1424 24.5682
LC4-1 GDSC1 -1.8145 3.9812 -5.0613 18.5502
BALL-1 GDSC1 -1.5601 4.2887 -5.0158 17.4263
MEG-01 GDSC1 -1.2921 5.182 -5.254 17.9725
ME1 GDSC1 -1.2789 3.604 -4.467 13.023
Granta-519 GDSC1 -1.2199 3.2675 -4.26 11.4312
Mono-Mac-6 GDSC1 -1.1351 4.8683 -4.9823 15.8915
SUP-B15 GDSC1 -1.063 3.7648 -4.3906 11.878
CML-T1 GDSC1 -1.0533 4.9983 -4.9861 15.6701
MC116 GDSC1; GDSC2 -1.0249 4.985 -4.9589 12.8388
LP-1 GDSC1; GDSC2 -1.0033 2.7692 -3.8702 6.5425
SK-MM-2 GDSC1 -0.9456 4.8977 -4.8589 14.5766
HDLM-2 GDSC1 -0.8042 2.7957 -3.7536 6.7711
RC-K8 GDSC1 -0.7689 3.5594 -4.0908 9.0345
MHH-CALL-2 GDSC1 -0.7582 3.7639 -4.1811 9.6268
ST486 GDSC1 -0.741 4.9191 -4.7246 13.16
L-428 GDSC1 -0.7343 4.206 -4.3764 10.8826
CA46 GDSC1 -0.6938 6.0151 -5.2238 16.0239
PF-382 GDSC1 -0.5957 5.2454 -4.7815 13.1203
OCI-AML-2 GDSC1 -0.5646 5.5156 -4.8904 13.7049
BC-3 GDSC2 -0.4145 10.7789 -7.3586 22.0107
Jurkat GDSC1 -0.3389 6.6384 -5.2764 15.3481
Ku812 GDSC1 -0.3332 5.0013 -4.4883 10.5911
JVM-2 GDSC1 -0.194 7.5418 -5.6127 16.7735
OPM-2 GDSC1 -0.1416 4.9381 -4.3357 9.1532
EM-2 GDSC1 -0.099 5.6749 -4.6542 11.0647
P30/OHK GDSC1 -0.0742 4.4986 -4.0909 7.4174
IM-9 GDSC1 -0.0721 1.3189 -2.7697 0.2233
P31/FUJ GDSC1 -0.0707 1.456 -2.817 0.3337
Daudi GDSC1 0.0325 2.7454 -3.2662 2.1337
SUP-T1 GDSC1 0.0404 4.6691 -4.1 7.2348
THP-1 GDSC1; GDSC2 0.0806 3.8699 -3.7191 3.8248
OCI-AML-5 GDSC1 0.2722 3.1541 -3.3188 2.1198
CESS GDSC1 0.2809 2.4962 -3.0582 0.9187
OCI-AML-3 GDSC1 0.3455 5.319 -4.2148 7.3385
Kasumi-1 GDSC1; GDSC2 0.3483 8.6425 -5.7702 13.8711
KM-H2 GDSC1 0.3532 3.0029 -3.2217 1.5546
NALM-6 GDSC1 0.3779 2.7594 -3.1172 1.0775
ML-2 GDSC1 0.4489 7.0284 -4.939 11.4858
OCI-M1 GDSC1 0.4588 4.925 -3.9744 5.6372
SUP-HD1 GDSC1 0.5212 2.611 -3.0048 0.5837
ARH-77 GDSC1 0.5786 9.7359 -6.1384 17.3974
GDM-1 GDSC1 0.626 2.7535 -3.0158 0.5628
KY821 GDSC1 0.6353 2.0462 -2.7702 0.0799
MOLM-13 GDSC1 0.6669 2.7015 -2.982 0.45
RPMI-6666 GDSC1 0.6909 2.5233 -2.9111 0.2774
L-1236 GDSC1 0.709 3.818 -3.3834 1.9562
CMK GDSC1 0.7569 2.0971 -2.7467 0.0488
⏷ Show the Full List of 164 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-GT-4 GDSC1 -8.8894 -5.9461 -8.9091 77.2764
FLO-1 GDSC1 -7.1964 -2.1507 -7.6893 57.625
OACP4 C GDSC1 -6.6568 -2.5661 -6.9883 53.3075
ESO-26 GDSC1 -5.7433 -2.7369 -5.9512 43.5239
TE-12 GDSC1; GDSC2 -4.5442 0.5112 -5.8466 28.9641
KYSE-220 GDSC1 -3.609 -0.3387 -4.5185 22.4244
KYSE-50 GDSC1 -2.6855 -0.0316 -3.7826 12.8811
HCE-4 GDSC1; GDSC2 -1.7009 1.6558 -3.8199 7.8099
KYAE-1 GDSC1 -1.5275 3.5407 -4.6203 14.8155
ESO-51 GDSC1 -0.3959 6.6387 -5.3163 15.723
OACM5.1 C GDSC1 0.051 6.13 -4.7717 11.4228
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 -6.4253 -2.7886 -6.6818 51.0802
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC1 -9.5236 -3.9734 -9.7998 74.5054
NB1 GDSC1 -7.8772 -4.9215 -7.9198 67.1785
SJNB-14 GDSC1 -7.6473 -5.6821 -7.652 66.0481
CHP-212 GDSC1 -7.1379 -3.7107 -7.274 58.6884
SK-N-SH GDSC1 -6.8396 -3.6407 -6.9648 55.6778
SK-N-MC-IXC GDSC1; GDSC2 -6.6376 -5.4738 -6.6379 43.3099
Kelly GDSC1 -6.5618 -3.9746 -6.6244 52.803
SJNB-17 GDSC1; GDSC2 -6.5135 -4.5321 -6.5306 42.1343
CHP-126 GDSC1; GDSC2 -5.9241 -2.868 -6.1186 37.0151
GOTO GDSC1 -5.9068 1.832 -7.8226 47.3365
SJNB-7 GDSC1 -5.7893 -0.7618 -6.6228 45.3275
TGW GDSC1 -5.5163 6.1208 -9.4311 46.3742
SJNB-13 GDSC1 -5.3335 -3.5368 -5.3736 37.8754
SiMa GDSC1 -5.2546 -2.615 -5.4475 37.6926
LA-N-6 GDSC1; GDSC2 -5.1745 -2.9288 -5.2929 29.2273
SJNB-5 GDSC1; GDSC2 -5.0401 -0.5992 -5.8879 31.419
SK-N-AS GDSC1 -4.5942 -1.3806 -5.1101 31.5497
SJNB-12 GDSC1 -4.3007 -1.6265 -4.7045 27.3589
SK-N-BE(2)-M17 GDSC1 -3.8682 -1.5755 -4.2591 21.9724
KP-N-YN GDSC1 -3.6507 5.2252 -7.253 35.1262
SK-N-FI GDSC1 -3.6147 2.539 -5.8989 30.2146
SJNB-6 GDSC1; GDSC2 -3.3165 0.4043 -4.5822 17.4065
SJNB-10 GDSC1 -3.3035 6.144 -7.3984 34.1422
KP-N-YS GDSC1; GDSC2 -2.9982 13.1569 -10.6319 36.2438
MHH-NB-11 GDSC1; GDSC2 -2.8724 3.223 -5.5655 21.2754
NH-12 GDSC1 -2.8695 1.5223 -4.7175 20.3809
GI-ME-N GDSC1 -1.8734 1.6488 -3.947 11.1789
KP-N-RT-BM-1 GDSC2 -0.4853 7.8462 -5.9685 16.6086
IMR-5 GDSC1 0.6861 6.3528 -4.4829 8.2936
NB(TU)1 GDSC1 0.7225 2.8114 -3 0.4735
SK-N-DZ GDSC1 1.0263 25.514 -13.5575 34.2408
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 -7.2958 -4.6021 -7.3375 61.1897
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-51 GDSC1 -9.394 -4.1929 -9.6214 74.5811
MDA-MB-468 GDSC1 -9.3378 -7.4073 -9.3384 84.6015
BT-549 GDSC1 -7.1329 -2.9311 -7.4193 57.8625
HCC1937 GDSC1 -6.5735 -1.9736 -7.0614 52.3331
MDA-MB-330 GDSC1; GDSC2 -6.4705 -1.8302 -6.9927 43.1049
MDA-MB-436 GDSC1 -6.457 -4.223 -6.4913 51.6239
CAL-120 GDSC1 -6.4238 -4.2583 -6.454 51.2299
Hs 578T GDSC1 -6.3149 -3.3077 -6.4554 49.9211
MDA-MB-361 GDSC1 -6.0775 -1.3352 -6.7268 47.7736
JIMT-1 GDSC1 -5.9769 -3.8822 -6.0173 45.8178
ZR-75-30 GDSC1 -5.9746 0.2686 -7.2254 47.3677
MFM-223 GDSC1 -5.9053 -1.8075 -6.3843 45.8903
HCC1419 GDSC1 -5.7798 4.0366 -8.6996 47.1569
BT-483 GDSC1 -5.7038 -3.7317 -5.7443 42.4645
T-47D GDSC1 -5.683 0.6857 -7.0943 45.2366
BT-474 GDSC1 -5.6772 -0.0695 -6.7744 44.7389
MCF-7 GDSC1 -5.6188 -0.3996 -6.5806 43.986
HCC2157 GDSC1 -5.6023 -4.4077 -5.6049 41.0194
MDA-MB-231 GDSC1 -5.5796 -2.7102 -5.7791 41.5885
HCC1395 GDSC1 -5.5321 -2.2539 -5.8441 41.4415
BT-20 GDSC1 -5.2041 -2.2343 -5.4917 37.5413
MDA-MB-453 GDSC1 -4.8414 0.5291 -6.1577 37.7302
Evsa-T GDSC1 -4.616 -1.4191 -5.1193 31.7354
HCC1143 GDSC1 -4.4305 -1.4061 -4.925 29.4877
HCC1187 GDSC1 -4.307 -0.5247 -5.1494 30.0722
EFM-19 GDSC1 -4.2205 -0.2796 -5.1658 29.6756
AU565 GDSC1 -4.0255 0.757 -5.4389 30.0705
COLO 824 GDSC1 -3.8632 0.874 -5.3343 28.6844
HCC1806 GDSC1 -3.844 -1.861 -4.1283 20.9332
CAL-85-1 GDSC1 -3.714 -0.7907 -4.422 22.2921
HCC70 GDSC1 -3.487 1.9004 -5.4683 27.552
HCC1599 GDSC2 -3.4759 0.2002 -4.6385 18.3206
DU4475 GDSC1 -3.4137 1.2741 -5.0948 25.146
HCC2218 GDSC1; GDSC2 -3.1077 1.6008 -4.9712 18.9128
HCC202 GDSC1 -3.0762 1.8205 -5.051 23.3616
MDA-MB-415 GDSC1 -2.9864 0.98 -4.5548 19.7893
OCUB-M GDSC1 -2.8518 2.5033 -5.1892 23.2194
YMB-1-E GDSC2 -2.5414 2.5273 -4.9318 16.8373
HCC1428 GDSC1 -2.4039 6.5226 -6.8127 28.9534
CAMA-1 GDSC1 -2.0995 2.0297 -4.3153 14.6402
HCC1500 GDSC1 -1.4237 2.5349 -4.0485 10.5279
HCC38 GDSC1 -1.11 5.0101 -5.0335 16.1243
MDA-MB-175-VII GDSC1 -0.8045 4.0691 -4.3584 10.9487
UACC-893 GDSC1; GDSC2 -0.8021 7.722 -6.1404 18.1351
HDQ-P1 GDSC1 -0.7507 3.3529 -3.9811 8.2305
HCC1569 GDSC1; GDSC2 -0.6664 5.3576 -4.8848 11.6049
MDA-MB-157 GDSC1 -0.5749 8.964 -6.5833 22.324
EFM-192A GDSC1 -0.1816 5.8106 -4.7726 11.9942
MRK-nu-1 GDSC1 0.5831 2.8246 -3.0582 0.7183
HCC1954 GDSC1 0.6442 2.4951 -2.9182 0.3068
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SF126 GDSC1; GDSC2 -8.7512 -5.0104 -8.8274 62.8877
GaMG GDSC1 -8.4751 -6.1914 -8.4807 74.9191
MOG-G-UVW GDSC1 -8.4476 -5.884 -8.4598 73.9812
MOG-G-CCM GDSC1 -8.1326 -6.4924 -8.1332 72.1533
PFSK-1 GDSC1 -7.4038 -3.9212 -7.5273 61.393
SF268 GDSC1 -7.2447 -3.7968 -7.3754 59.786
GB-1 GDSC1 -7.174 -4.5457 -7.2147 59.8681
H4 GDSC1 -7.0182 -5.042 -7.0278 58.4819
SK-MG-1 GDSC1 -6.9961 -5.1811 -7.0018 58.2799
42-MG-BA GDSC1 -6.7571 -3.9374 -6.8357 54.9708
8-MG-BA GDSC1 -6.7396 -5.4557 -6.7402 55.209
U-251MG GDSC1 -6.7395 -2.085 -7.2096 53.8414
GI-1 GDSC1 -6.6709 -4.7184 -6.6841 54.2642
ONS-76 GDSC1 -6.4974 -3.9149 -6.5629 52.0518
D-423MG GDSC1; GDSC2 -6.2055 -4.6894 -6.2105 38.9962
D-542MG GDSC1; GDSC2 -6.1962 -1.0865 -6.9419 41.2776
KS-1 [Human Krukenberg tumour] GDSC1 -5.979 -2.7157 -6.2128 46.2606
D-566MG GDSC1; GDSC2 -5.8662 -4.3484 -5.8743 35.6074
DK-MG GDSC1 -5.8232 -2.2498 -6.1629 44.7598
LNZTA3WT4 GDSC1 -5.7185 -4.2402 -5.7271 42.5021
M059J GDSC1 -5.7143 -2.9311 -5.8774 43.0455
LN-18 GDSC1 -5.6862 -0.0313 -6.7994 44.8418
DBTRG-05MG GDSC1 -5.6101 -2.684 -5.8184 41.9775
KNS-81-FD GDSC1; GDSC2 -5.5683 -2.4838 -5.8219 33.7906
Becker GDSC1 -5.4543 -2.9713 -5.5875 39.823
SF539 GDSC1 -5.4264 -3.5447 -5.4709 39.0526
YKG-1 GDSC1; GDSC2 -5.403 -4.1944 -5.407 30.9392
Daoy GDSC1 -5.3804 -3.497 -5.4275 38.4954
A-172 GDSC1 -5.3285 -1.9498 -5.7118 39.393
YH-13 GDSC1 -5.2536 -0.8505 -6.0162 39.9413
SF295 GDSC1; GDSC2 -5.0755 -0.8636 -5.8212 31.2936
Onda 11 GDSC1; GDSC2 -5.0649 -0.1233 -6.1088 32.4742
D-245MG GDSC2 -5.0583 0.0693 -6.1829 32.7413
T98G GDSC1 -5.0528 -2.7591 -5.1952 34.9729
D283 Med GDSC1 -4.9336 -1.393 -5.4706 35.5815
D-502MG GDSC1; GDSC2 -4.7458 -0.2494 -5.7227 29.2963
D-336MG GDSC1; GDSC2 -4.595 -1.7641 -4.9746 24.8216
D-247MG GDSC1; GDSC2 -4.2943 1.4389 -6.0223 28.6771
SW1088 GDSC1 -4.059 0.1892 -5.2109 29.0404
D-263MG GDSC1 -3.9203 -2.6704 -3.985 20.3953
D-392MG GDSC1 -3.5994 0.0453 -4.6865 23.4994
KALS-1 GDSC1 -3.4791 -1.6423 -3.8186 16.7979
LN-229 GDSC1 -3.2503 3.1202 -5.8507 28.3541
LN-405 GDSC1 -3.2199 3.8754 -6.1975 29.736
CAS-1 GDSC1 -3.0637 -0.8574 -3.7371 14.1645
SW1783 GDSC1 -2.8844 -0.32 -3.8231 14.0219
AM-38 GDSC1 -2.8758 2.5134 -5.2154 23.4696
NMC-G1 GDSC1; GDSC2 -2.8369 4.3634 -6.1029 23.69
Hs 683 GDSC1; GDSC2 -2.6301 3.9173 -5.702 21.1659
KNS-42 GDSC1; GDSC2 -2.3999 -0.304 -3.3966 7.0337
KINGS-1 GDSC1 -2.3237 5.5184 -6.2435 26.4255
SNB-75 GDSC1; GDSC2 -1.9003 2.6625 -4.472 12.2961
U-87MG ATCC GDSC1 -1.5285 5.0257 -5.3573 19.309
U-118MG GDSC1 -0.2831 5.1087 -4.5064 10.5838
Onda 10 GDSC1; GDSC2 -0.0242 5.8554 -4.691 9.2135
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 -5.7904 4.3854 -8.8731 47.2992
ETK-1 GDSC1 -4.7832 -1.837 -5.1545 32.9798
TGBC1TKB GDSC1 -4.7475 -2.6685 -4.8831 31.1646
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AN3-CA GDSC1 -6.8024 -2.9857 -7.0477 54.904
EN GDSC1 -5.6679 -1.9293 -6.0878 43.2734
MFE-319 GDSC1 -5.3663 -2.6989 -5.5496 38.9895
MFE-296 GDSC1 -5.299 -2.9579 -5.422 37.885
ESS-1 GDSC1 -4.7706 -0.2076 -5.7662 35.8365
RL95-2 GDSC1 -4.6384 -1.2996 -5.1878 32.2526
MFE-280 GDSC1 -3.0203 0.4125 -4.3073 18.2039
KLE GDSC1 -1.7117 3.5302 -4.7563 16.3029
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMRC-20 GDSC1 -8.6736 -4.4542 -8.8093 71.7766
KTCTL-140 GDSC1; GDSC2 -7.5799 -4.1228 -7.6874 52.5394
SW13 GDSC1 -7.2424 -4.545 -7.2862 60.5814
HA7-RCC GDSC1; GDSC2 -7.1149 -4.5321 -7.1541 48.1526
769-P GDSC1 -6.56 -4.7232 -6.5705 52.9264
LB1047-RCC GDSC1; GDSC2 -6.1357 -3.9694 -6.176 38.4565
KTCTL-195 GDSC1 -6.1327 -0.8559 -6.9565 48.3877
786-O GDSC1 -6.0445 -4.2178 -6.0632 46.5895
RXF 393L GDSC1; GDSC2 -6.0162 -4.2962 -6.0301 37.1396
KTCTL-1M GDSC1; GDSC2 -5.7695 0.2174 -6.9887 38.9997
KTCTL-26A GDSC1; GDSC2 -5.7225 -1.0953 -6.4279 37.0436
KTCTL-13 GDSC1; GDSC2 -5.6523 -2.785 -5.8413 34.3222
A-704 GDSC1 -5.3813 -3.5622 -5.4214 38.4694
Caki-1 GDSC1; GDSC2 -5.2236 -1.7851 -5.6499 31.2314
SW156 GDSC1; GDSC2 -5.1143 -2.1545 -5.4167 29.5585
SN12C GDSC1 -5.0774 -1.6993 -5.5195 36.7808
BFTC-909 GDSC1 -4.6661 -3.082 -4.7199 29.6408
TK-10 GDSC1 -4.5767 -2.122 -4.84 29.8462
OS-RC-2 GDSC1 -4.5135 0.291 -5.7172 34.0856
NCC010 GDSC1; GDSC2 -4.358 1.8402 -6.2733 29.9892
A-498 GDSC1 -4.3419 -2.4485 -4.4931 26.2258
BB65-RCC GDSC1; GDSC2 -3.6735 1.8652 -5.6264 24.3974
KMRC-1 GDSC1 -3.6159 -0.3294 -4.5296 22.5346
VMRC-RCZ GDSC1 -3.4591 -0.9972 -4.0699 18.5153
KTCTL-21 GDSC1; GDSC2 -2.8188 0.7785 -4.3034 14.0187
NCC021 GDSC1; GDSC2 -2.2965 1.9739 -4.4487 13.2776
UO-31 GDSC1; GDSC2 -1.9693 0.8784 -3.6385 7.3607
LB2241-RCC GDSC1; GDSC2 -1.1689 3.6955 -4.4322 10.2127
VMRC-RCW GDSC1; GDSC2 -0.6501 2.9165 -3.7137 4.9605
RCC10RGB GDSC1 0.3457 2.2386 -2.9383 0.4761
CAL-54 GDSC1 0.4846 8.9031 -5.8029 16.0273
ACHN GDSC1 1.0903 10.1757 -6.0071 15.6082
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCT 15 GDSC1 -6.5992 -1.3569 -7.285 52.3724
RKO GDSC1 -5.6097 -3.6046 -5.6581 41.3385
MDST8 GDSC1 -5.5515 -3.5488 -5.6028 40.6342
SNU-407 GDSC1 -5.3341 -3.0052 -5.4511 38.2842
SW626 GDSC1 -5.1611 -2.4314 -5.3912 36.7526
SW620 GDSC1; GDSC2 -4.8576 -2.6037 -5.0176 26.2725
C2BBe1 GDSC1 -4.6616 -3.6684 -4.6667 29.2777
HCT 116 GDSC1 -4.546 -2.6429 -4.6696 28.5873
COLO 678 GDSC1 -4.4646 -0.4171 -5.359 32.1067
NCI-H747 GDSC1 -4.2701 -1.6754 -4.6541 26.8587
LS123 GDSC1 -4.2474 -0.7051 -5.011 28.9407
SK-CO-1 GDSC1 -4.054 -1.4029 -4.5238 24.7876
SNU-C5 GDSC1 -3.8868 1.3181 -5.5676 29.9961
LoVo GDSC1 -3.6229 -1.0123 -4.2316 20.4958
SNU-C2B GDSC1 -3.6146 0.4011 -4.8685 24.7391
LS513 GDSC1 -3.611 -1.9386 -3.8494 17.7182
HT-29 GDSC1; GDSC2 -3.5627 -0.7144 -4.3014 16.6629
SW837 GDSC1 -3.2492 2.8248 -5.7037 27.6541
LS411N GDSC1 -3.2487 -1.5685 -3.6058 14.0741
SW48 GDSC1 -3.2072 -1.0659 -3.7834 15.1836
HCC2998 GDSC1 -2.6544 -0.0192 -3.7609 12.588
GP5d GDSC1 -2.455 -0.1484 -3.5215 9.9466
CW-2 GDSC1 -2.0254 5.2739 -5.8756 23.6871
CL-11 GDSC1 -1.8196 2.536 -4.346 13.8963
HT115 GDSC1; GDSC2 -1.7326 0.3947 -3.226 4.2206
SW1463 GDSC1 -1.7108 1.0008 -3.5056 7.3264
NCI-H716 GDSC1 -1.4536 6.4152 -5.9896 22.3176
CCK-81 GDSC1 -1.4205 1.5908 -3.5876 7.1251
RCM-1 [Human ESC] GDSC1 -1.2512 1.0196 -3.2071 3.9213
CaR-1 GDSC1 -1.2125 2.8395 -4.0467 9.9077
KM12 GDSC1 -1.19 2.2503 -3.7474 7.6863
T84 GDSC1 -0.8288 2.5764 -3.6668 6.2194
SW1417 GDSC1 -0.6904 4.893 -4.6768 12.7199
DiFi GDSC1 -0.5776 3.2864 -3.84 6.8481
SNU-81 GDSC1; GDSC2 -0.2839 2.7326 -3.4209 2.8118
LS180 GDSC1 -0.2453 2.0532 -3.1165 1.6821
COLO 320HSR GDSC1 -0.2289 6.3195 -5.0473 13.7523
HT-55 GDSC1 -0.2 4.9639 -4.3848 9.6048
SW1116 GDSC1 -0.0419 3.1879 -3.4889 3.5164
NCI-H508 GDSC1; GDSC2 0.0901 7.0241 -5.1699 11.4863
SW948 GDSC1 0.3173 1.8244 -2.8046 0.1809
SNU-283 GDSC2 0.3512 8.9037 -5.8935 14.4307
SNU-61 GDSC1 0.4081 5.4043 -4.2169 7.2271
COLO205 GDSC1 0.5737 2.7031 -3.0178 0.5955
SNU-C1 GDSC1 0.5775 2.9838 -3.1191 0.9361
LS1034 GDSC1 0.8737 2.2466 -2.7569 0.0468
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 -1.5216 9.8554 -7.7572 29.1906
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 GDSC1 -7.78 -4.9517 -7.8166 66.3651
Hep 3B2.1-7 GDSC1; GDSC2 -6.8384 -4.9053 -6.8487 45.3574
HuH-1 GDSC1 -6.7826 -3.2238 -6.9767 54.8503
HLE GDSC1 -6.4034 -3.6766 -6.4927 50.9402
SNU-423 GDSC1 -5.967 -2.2872 -6.3095 46.3136
SNU-449 GDSC1 -5.9548 -3.9593 -5.9874 45.5241
SNU-387 GDSC1 -5.6057 -2.2198 -5.934 42.3257
JHH-6 GDSC1 -5.5778 -3.3373 -5.6582 41.0896
JHH-2 GDSC1 -5.4627 -3.683 -5.4956 39.4421
JHH-1 GDSC1 -5.4159 -3.1464 -5.5143 39.1931
Huh-7 GDSC1 -5.3704 -1.3276 -5.965 40.6118
JHH-7 GDSC1 -4.6332 -0.8713 -5.3484 33.0663
JHH-4 GDSC1 -2.756 0.8206 -4.2681 16.8024
Hep-G2/C3A GDSC1 -0.4762 1.8781 -3.1563 2.1995
SK-HEP-1 GDSC1 -0.1679 3.2562 -3.5863 4.3335
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 184 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H292 GDSC1; GDSC2 -8.9254 -8.0332 -8.9254 66.2654
ABC-1 GDSC1; GDSC2 -8.8328 -5.7659 -8.8589 64.3367
NCI-H1563 GDSC1 -8.1176 -2.605 -8.5719 64.5192
NCI-H1703 GDSC1 -7.7548 -3.604 -7.9566 63.8054
NCI-H2818 GDSC1 -7.7207 -4.2278 -7.8238 64.6043
NCI-H460 GDSC1; GDSC2 -7.3856 -4.26 -7.4643 50.7667
NCI-H2369 GDSC1 -7.3841 0.571 -8.8378 56.6336
A-427 GDSC1; GDSC2 -7.2987 -5.1755 -7.3098 49.9426
NCI-H1975 GDSC1 -7.252 -5.4338 -7.2563 61.4029
NCI-H841 GDSC1 -7.2218 -4.3196 -7.285 60.1401
SBC-3 GDSC1 -7.1393 -4.3191 -7.1982 59.2986
ChaGo-K-1 GDSC1; GDSC2 -7.1036 -3.1675 -7.3362 48.2205
COR-L105 GDSC1 -7.0635 -3.8371 -7.1754 58.0878
NCI-H2066 GDSC1 -6.9519 -2.3725 -7.3611 55.8399
HCC33 GDSC2 -6.9506 -5.3339 -6.9533 46.4577
NCI-H838 GDSC1; GDSC2 -6.9493 -4.7749 -6.9675 46.4827
NCI-H661 GDSC1 -6.9078 -4.242 -6.962 56.7828
DMS 273 GDSC1 -6.9057 -5.6531 -6.9061 57.2821
NCI-H1944 GDSC1 -6.7808 -2.7799 -7.0711 54.5798
KNS-62 GDSC1 -6.7272 -3.9539 -6.802 54.6513
NCI-H2171 GDSC2 -6.7047 -4.5475 -6.727 44.0605
NCI-H1693 GDSC1 -6.6984 -4.3222 -6.7356 54.4746
NCI-H2085 GDSC1 -6.6954 -3.4998 -6.8325 54.1025
EMC-BAC-2 GDSC1 -6.6869 -3.5032 -6.8228 54.0148
NCI-H1355 GDSC1 -6.6526 -4.0777 -6.7094 53.8664
DMS 114 GDSC1 -6.5004 -3.4769 -6.6266 51.9993
SW1573 GDSC1 -6.4474 -3.2398 -6.6109 51.3783
SK-LU-1 GDSC1 -6.4156 -3.8502 -6.4837 51.0976
NCI-H2461 GDSC1 -6.3753 -2.5658 -6.6814 50.5467
RERF-LC-KJ GDSC1 -6.2937 -2.2789 -6.6683 49.7183
NCI-H23 GDSC1 -6.2921 -3.4393 -6.4087 49.6598
HARA [Human squamous cell lung carcinoma] GDSC1 -6.2191 -2.8643 -6.4402 48.8895
NCI-H1755 GDSC1 -6.1999 -2.6379 -6.4721 48.713
HOP-92 GDSC1 -6.1282 -3.6972 -6.1969 47.7053
A-549 GDSC1 -6.1221 -4.1249 -6.1495 47.5636
RERF-LC-MS GDSC1; GDSC2 -6.114 -1.8159 -6.6088 39.874
NCI-H1155 GDSC1 -6.019 -2.2423 -6.3787 46.8894
LXF 289 GDSC1 -5.905 -2.9785 -6.0746 45.2884
NCI-H2170 GDSC1 -5.8473 -2.0548 -6.2454 45.1415
EMC-BAC-1 GDSC1; GDSC2 -5.8367 -3.6171 -5.8971 35.5619
HCC366 GDSC1; GDSC2 -5.8299 -2.3227 -6.1501 36.6118
NCI-H290 GDSC1; GDSC2 -5.8022 -2.4894 -6.0757 36.1558
NCI-H2009 GDSC1 -5.7793 -2.4974 -6.0486 44.1046
LB647-SCLC GDSC1; GDSC2 -5.6764 0.8154 -7.1427 38.9163
NCI-H1048 GDSC1 -5.6695 -1.2105 -6.3294 43.8617
HOP-62 GDSC1 -5.6426 -1.3003 -6.2686 43.5171
NCI-H2731 GDSC1 -5.554 -2.7556 -5.741 41.2401
NCI-H1299 GDSC1 -5.5506 -4.4849 -5.5518 40.3659
HCC44 GDSC1 -5.5336 -4.4087 -5.5356 40.1578
COR-L303 GDSC2 -5.5297 -3.6204 -5.572 32.4011
NCI-H196 GDSC1 -5.5072 -1.083 -6.2006 42.317
LK-2 GDSC1 -5.5025 -3.095 -5.6166 40.3213
SBC-5 GDSC1 -5.4506 -3.0033 -5.5773 39.7484
NCI-H2030 GDSC1; GDSC2 -5.3279 -0.3534 -6.2909 34.4801
NCI-H524 GDSC1 -5.3262 -3.0539 -5.4336 38.1394
NCI-H1341 GDSC1 -5.3095 -2.1848 -5.6208 38.8799
NCI-H2722 GDSC1 -5.2836 0.8942 -6.7714 42.1191
NCI-H1581 GDSC1 -5.1972 -2.3568 -5.4503 37.2966
PC-14 GDSC1; GDSC2 -5.1866 -2.5404 -5.3914 29.7857
NCI-H1650 GDSC1 -5.1623 -3.1984 -5.2338 35.926
EBC-1 GDSC1 -5.1098 -2.3423 -5.3589 36.2325
NCI-H1781 GDSC1 -5.0617 -0.8074 -5.8284 37.9611
EPLC-272H GDSC1 -4.9929 -2.2027 -5.2703 34.9786
NCI-H650 GDSC1 -4.9243 -0.376 -5.8566 37.1666
NCI-H2347 GDSC1 -4.9081 -2.2481 -5.1647 33.8439
VMRC-LCD GDSC1 -4.8457 -1.469 -5.3485 34.4088
LOU-NH91 GDSC1 -4.7555 -2.643 -4.8975 31.3032
COR-L95 GDSC1 -4.7288 -0.8999 -5.4383 34.1068
LC-2/ad GDSC1; GDSC2 -4.7119 -0.6195 -5.5334 28.239
Lu-135 GDSC1 -4.6429 1.6946 -6.4858 37.6278
NCI-H2810 GDSC1; GDSC2 -4.6081 -1.2563 -5.1716 25.9292
NCI-H2228 GDSC1 -4.6002 0.0305 -5.6917 34.4851
NCI-H2869 GDSC1; GDSC2 -4.5698 -2.2171 -4.8045 23.7915
HCC15 GDSC1 -4.5179 0.0898 -5.633 33.7383
NCI-H596 GDSC1 -4.4172 -2.0375 -4.6922 27.9606
EKVX GDSC1; GDSC2 -4.3783 -0.4282 -5.2645 25.4048
NCI-H2373 GDSC1 -4.3758 1.6447 -6.1989 35.2263
NCI-H2342 GDSC1 -4.3587 -0.4753 -5.2241 30.7796
SW1271 GDSC1 -4.3494 2.6117 -6.6307 36.5181
NCI-H2405 GDSC1 -4.3382 0.7871 -5.7639 33.2948
NCI-H1304 GDSC1 -4.3077 -0.4729 -5.1722 30.2028
NCI-H1963 GDSC1 -4.2427 -1.0172 -4.8771 28.11
IST-SL1 GDSC1; GDSC2 -4.0799 -1.4577 -4.5303 20.1012
NCI-H647 GDSC1; GDSC2 -4.0799 -1.2785 -4.6 20.4947
NCI-H2023 GDSC1 -4.0376 1.4712 -5.7866 31.7888
HCC827 GDSC1 -4.0196 -2.1446 -4.2259 22.5817
CAL-12T GDSC1; GDSC2 -3.6734 0.8095 -5.1192 21.7772
NCI-H146 GDSC1; GDSC2 -3.6557 0.7309 -5.0647 21.4125
NCI-H1869 GDSC1 -3.6382 0.2971 -4.8426 24.6934
NCI-H2804 GDSC1; GDSC2 -3.637 0.0686 -4.7346 19.4846
NCI-H1651 GDSC1 -3.5803 2.5835 -5.8888 30.0098
IA-LM GDSC1 -3.53 2.5393 -5.8204 29.4685
RERF-LC-Sq1 GDSC1 -3.4373 2.516 -5.7234 28.5905
NCI-H1437 GDSC1; GDSC2 -3.3654 1.1507 -4.9895 19.9229
NCI-H520 GDSC1 -3.318 1.6253 -5.1767 25.1787
BEN GDSC1; GDSC2 -3.2917 1.7215 -5.1994 20.8093
NCI-H358 GDSC1 -3.2839 1.6288 -5.1469 24.8518
NCI-H2122 GDSC1 -3.0886 -1.106 -3.6462 13.5951
NCI-H810 GDSC1 -3.0764 -0.1369 -4.0929 16.889
LCLC-103H GDSC1 -3.0132 1.0413 -4.6094 20.2752
NCI-H2227 GDSC1; GDSC2 -2.9745 0.875 -4.4922 15.6779
NCI-H2595 GDSC1 -2.9573 3.6956 -5.8753 27.227
NCI-H226 GDSC1 -2.9336 0.4212 -4.2315 17.2822
NCI-H1792 GDSC1 -2.856 -1.4747 -3.2445 9.4735
NCI-H720 GDSC1 -2.7874 1.8347 -4.7998 20.5744
NCI-H1568 GDSC1 -2.4706 2.5793 -4.8975 19.9291
NCI-H835 GDSC1 -2.3455 2.3245 -4.6648 17.9475
LCLC-97TM1 GDSC1 -2.3406 1.4588 -4.2279 14.8863
NCI-H748 GDSC2 -2.2869 1.0395 -3.9735 10.3351
NCI-H1573 GDSC1 -2.2853 1.4484 -4.1766 14.3085
NCI-H446 GDSC1 -2.2851 0.7007 -3.8027 11.4998
NCI-H3122 GDSC1 -2.277 4.6705 -5.7808 24.1288
NCI-H1734 GDSC1; GDSC2 -2.251 5.0521 -5.95 21.1756
NCI-H2795 GDSC1 -2.2488 8.7626 -7.8034 31.5602
NCI-H1915 GDSC1 -2.237 0.5032 -3.6644 10.2599
NCI-H2803 GDSC1; GDSC2 -2.2097 0.4988 -3.6399 8.0205
NCI-H2172 GDSC1; GDSC2 -2.2053 -0.4791 -3.1481 4.9016
NCI-H1666 GDSC1 -2.1996 -0.0629 -3.3512 7.6819
SBC-1 GDSC1; GDSC2 -2.1378 3.5242 -5.093 16.5184
NCI-H1092 GDSC1 -2.0919 3.7719 -5.1794 20.2233
NCI-H1623 GDSC1 -2.0715 11.5528 -9.0517 33.9964
NCI-H1648 GDSC1 -2.058 2.6823 -4.6077 16.5147
NCI-H1688 GDSC1 -2.0277 1.2512 -3.8696 11.1091
Ms-1 GDSC1 -1.9738 4.2721 -5.3335 20.684
Lu-139 GDSC1 -1.6572 4.2449 -5.0692 18.0678
NCI-H513 GDSC1 -1.5953 4.2439 -5.0207 17.571
PaCa-3 GDSC1 -1.5693 5.1526 -5.452 19.9638
SK-MES-1 GDSC1 -1.5664 1.8787 -3.8307 9.3528
NCI-H1838 GDSC1 -1.5467 17.9796 -11.8341 37.0833
NCI-H847 GDSC1 -1.5336 2.6197 -4.1705 11.7356
Calu-3 GDSC1 -1.4573 1.0857 -3.3702 5.6034
SHP-77 GDSC1 -1.435 1.9197 -3.7568 8.4228
NCI-H250 GDSC2 -1.2248 1.4853 -3.4073 4.2589
IST-SL2 GDSC1; GDSC2 -1.1961 2.8653 -4.0478 8.0097
NCI-H3255 GDSC1; GDSC2 -1.1554 2.3427 -3.7683 6.2549
COLO 668 GDSC1 -1.128 1.8229 -3.5039 5.7632
NCI-H1876 GDSC1 -1.0906 1.7495 -3.4459 5.2584
NCI-H1793 GDSC1 -1.0262 8.0731 -6.483 23.2002
NCI-H2196 GDSC2 -0.9942 2.0689 -3.5341 4.5602
Lu-134-A GDSC1; GDSC2 -0.9675 6.9997 -5.9077 17.4873
NCI-H2141 GDSC1 -0.935 3.7608 -4.2994 10.9027
COR-L23 GDSC1 -0.9194 2.7206 -3.7921 7.3194
NCI-H345 GDSC1; GDSC2 -0.869 4.1731 -4.4528 9.6483
NCI-H727 GDSC1 -0.8628 2.7881 -3.7873 7.1481
NCI-H740 GDSC2 -0.8139 2.6246 -3.6799 5.0647
NCI-H2135 GDSC1; GDSC2 -0.8095 1.5039 -3.17 2.2538
NCI-H82 GDSC1 -0.809 4.9009 -4.7634 13.5926
COR-L321 GDSC1; GDSC2 -0.7271 1.5111 -3.1292 1.9395
NCI-H526 GDSC1 -0.7158 2.5524 -3.5863 5.4078
NCI-H2110 GDSC1; GDSC2 -0.648 11.4079 -7.8466 24.1705
NCI-H211 GDSC1 -0.6399 8.119 -6.2156 20.9183
NCI-H2591 GDSC1 -0.5493 9.1713 -6.6664 22.593
NCI-H1694 GDSC1 -0.458 4.9301 -4.5369 11.2159
NCI-H1770 GDSC1; GDSC2 -0.3042 5.7281 -4.815 10.4443
NCI-H1105 GDSC1; GDSC2 -0.2698 5.4339 -4.6519 9.4906
Lu-99A GDSC1 -0.223 8.1047 -5.9064 18.3245
NCI-H2087 GDSC1 -0.1852 4.778 -4.2885 8.948
Calu-6 GDSC1 -0.1388 5.0724 -4.3966 9.5375
NCI-H64 GDSC1 -0.1351 5.6324 -4.6576 11.1731
COR-L279 GDSC1 -0.1105 2.6498 -3.2964 2.4876
NCI-H2029 GDSC1; GDSC2 -0.0653 3.1415 -3.4813 2.8256
DMS 79 GDSC1; GDSC2 0.0065 3.4272 -3.5664 3.1532
NCI-H2291 GDSC1; GDSC2 0.0156 4.8721 -4.2079 6.5274
NCI-H209 GDSC1 0.0292 7.9956 -5.677 16.5246
NCI-H69 GDSC1 0.1565 3.7676 -3.6336 4.0725
NCI-H1436 GDSC1; GDSC2 0.1591 3.8234 -3.6563 3.3989
NCI-H510A GDSC1; GDSC2 0.1648 3.5661 -3.5429 2.8351
NCI-H2444 GDSC1; GDSC2 0.1774 5.2893 -4.3014 6.75
NCI-H2081 GDSC1; GDSC2 0.2151 14.3437 -8.6465 24.6153
NCI-H187 GDSC1 0.2166 4.3233 -3.8435 5.2629
CPC-N GDSC1 0.2305 3.705 -3.5681 3.5636
HCC78 GDSC1 0.2422 2.4621 -3.0614 0.9603
LC-1/sq GDSC1 0.2555 7.2995 -5.1915 13.3698
Lu-65 GDSC1 0.306 5.9189 -4.5127 9.2645
UMC-11 GDSC1 0.3942 3.9069 -3.5699 3.3315
NCI-H1993 GDSC1 0.4013 2.0256 -2.8436 0.2294
DMS 53 GDSC1 0.4314 2.9072 -3.1508 1.172
COR-L32 GDSC2 0.5111 3.4622 -3.332 1.5425
Lu-165 GDSC1 0.5417 2.2218 -2.8609 0.2233
NCI-H1435 GDSC1 0.6363 3.1055 -3.1406 0.9746
COR-L88 GDSC1 0.7417 11.399 -6.8275 19.9535
NCI-H322M GDSC1 0.7784 7.0685 -4.7539 9.7017
NCI-H1836 GDSC1; GDSC2 0.8513 2.3951 -2.8128 0.0767
NCI-H441 GDSC1 0.9677 2.8641 -2.9297 0.236
⏷ Show the Full List of 184 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 -0.3509 3.6045 -3.8482 6.406
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OE21 GDSC1 -7.3798 -5.9186 -7.3805 63.1286
TE-8 GDSC1 -6.8046 -5.5305 -6.8051 56.02
T.T GDSC1 -6.2377 -4.4742 -6.2498 48.9609
TE-4 GDSC1 -6.2012 -0.9703 -6.9887 48.9649
TE-5 GDSC1 -6.1345 -4.1317 -6.1619 47.7147
KYSE-140 GDSC1 -5.8585 -3.7912 -5.9013 44.3759
KYSE-410 GDSC1 -5.4745 -3.005 -5.6029 40.0453
KYSE-180 GDSC1 -5.4338 -2.9207 -5.5752 39.6114
KYSE-450 GDSC1 -5.0201 -3.4009 -5.0571 33.9542
EC-GI-10 GDSC1 -4.4118 -1.5339 -4.8578 28.9683
OE19 GDSC1 -4.3999 -0.8223 -5.1221 30.4559
TE-1 GDSC1 -4.3812 -1.6352 -4.7882 28.3564
KYSE-70 GDSC1 -4.2745 -1.9352 -4.5697 26.3347
KYSE-270 GDSC1 -4.2437 -1.4042 -4.7257 27.1677
TE-11 GDSC1; GDSC2 -3.691 -1.0058 -4.3047 17.19
KYSE-150 GDSC1 -3.4745 -0.9893 -4.0891 18.731
TE-9 GDSC1 -3.2065 1.097 -4.8148 22.4783
KYSE-520 GDSC1 -3.1249 0.5949 -4.4937 19.9773
TE-6 GDSC1 -2.8371 3.529 -5.6871 25.8298
TE-10 GDSC1; GDSC2 -2.5392 -0.0386 -3.6494 9.0563
KYSE-510 GDSC1; GDSC2 -2.0863 5.9185 -6.2475 22.0197
COLO 680N GDSC1 -1.6308 1.8045 -3.8413 9.6255
TE-15 GDSC1 -0.2758 4.5929 -4.2592 8.9677
OE33 GDSC1 0.6906 2.7933 -3.0056 0.5028
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVCAR-5 GDSC1 -9.1958 -5.1675 -9.2801 76.5457
JHOS-4 GDSC1; GDSC2 -9.159 -5.6508 -9.2025 66.7174
DOV13 GDSC1 -8.6425 -6.506 -8.6455 77.0367
OVTOKO GDSC1 -7.7979 -5.6141 -7.8059 67.5565
OVCAR-8 GDSC1 -7.7642 -5.5101 -7.7744 67.0739
IGROV-1 GDSC1 -7.4486 -3.9659 -7.5687 61.8532
A2780 GDSC1 -7.3794 -6.0742 -7.3796 63.1677
OVCAR-4 GDSC1 -7.282 -5.9206 -7.2824 61.9464
SK-OV-3 GDSC1 -7.1682 -3.3869 -7.3627 58.6359
TOV-21G GDSC1 -6.9706 -3.9095 -7.0663 57.2125
EFO-27 GDSC1; GDSC2 -6.7509 -3.4504 -6.9007 44.842
JHOS-2 GDSC1; GDSC2 -6.7343 -4.6195 -6.7538 44.3468
OVISE GDSC1 -6.7052 -5.1672 -6.7079 54.7583
OV56 GDSC1 -6.6988 2.0504 -8.732 52.1841
TOV-112D GDSC1 -6.6158 -4.168 -6.662 53.4739
OV-90 GDSC1 -6.5581 -4.0885 -6.6088 52.7873
ES-2 GDSC1 -6.4908 -2.2337 -6.8959 51.6347
TYK-nu GDSC1 -6.2258 -3.1273 -6.3925 48.9313
Caov-4 GDSC1 -5.5667 0.8257 -7.0335 44.3908
OVK18 GDSC1; GDSC2 -5.1912 -0.9072 -5.9278 32.329
FU-OV-1 GDSC1 -4.9089 0.543 -6.2329 38.3863
OAW42 GDSC1 -3.9733 -1.2081 -4.5154 24.2915
OVCAR-3 GDSC1 -3.5812 -1.4964 -3.985 18.5212
Kuramochi GDSC1 -3.5574 0.5605 -4.8885 24.584
OVKATE GDSC1 -3.4668 2.7786 -5.8795 29.4475
EFO-21 GDSC1 -3.0201 1.2153 -4.7015 20.9186
OC 314 GDSC1 -2.8215 5.6422 -6.7276 30.1765
OAW28 GDSC1 -1.1671 19.3059 -12.1891 36.7005
Caov-3 GDSC2 0.8689 2.4572 -2.8273 0.0873
RMG-I GDSC1 1.3878 10.4309 -5.9354 14.6242
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-4 GDSC1 -8.862 -4.9006 -8.9554 74.0472
PaTu 8988t GDSC1 -8.1926 -4.2774 -8.3201 68.3043
PSN1 GDSC1 -8.0681 -6.4129 -8.0689 71.3709
SW1990 GDSC1 -7.8184 -4.5882 -7.8867 66.0629
Panc 08.13 GDSC1 -6.7873 -1.468 -7.4525 53.94
SU.86.86 GDSC1 -6.7393 -5.1934 -6.742 55.1803
MIA PaCa-2 GDSC1 -6.3772 -3.7234 -6.4585 50.6427
DAN-G GDSC1 -5.9076 -4.4044 -5.9149 44.8531
Panc 02.03 GDSC1 -5.8805 -3.6625 -5.9382 44.6941
HPAC GDSC1 -5.8414 -4.3436 -5.8491 44.0299
KP-2 GDSC1 -5.7688 -3.8888 -5.7987 43.2225
HuP-T4 GDSC1 -5.4181 -2.921 -5.5582 39.4159
PaTu 8902 GDSC1 -5.3131 -2.6028 -5.5141 38.4335
SUIT-2 GDSC1 -5.1963 -2.5569 -5.398 37.0339
HuP-T3 GDSC1 -4.8383 -2.6171 -4.9935 32.4067
Panc 03.27 GDSC1 -4.7966 -1.7381 -5.2019 33.3244
KP-1N GDSC1 -4.7641 6.6577 -8.9801 42.9027
Hs 766T GDSC1 -4.6833 -1.282 -5.2424 32.8253
KP-3 GDSC1 -4.6188 -1.3803 -5.1367 31.8503
HPAF-II GDSC1 -4.581 -2.6358 -4.7093 29.0525
AsPC-1 GDSC1 -4.2376 -2.9497 -4.2806 24.2194
YAPC GDSC1 -3.721 0.4102 -4.977 25.9337
PL4 GDSC1 -3.5454 -0.3034 -4.4712 21.7869
Panc 10.05 GDSC1 -3.2233 -0.9188 -3.8667 15.8805
Capan-1 GDSC1 -2.6164 2.7941 -5.1293 21.9127
Panc 04.03 GDSC1 -2.5031 1.2967 -4.2844 15.912
BxPC-3 GDSC1 -2.092 11.7062 -9.1454 34.2445
QGP-1 GDSC1; GDSC2 -2.0653 0.6628 -3.6062 7.4119
MZ-PC-1 GDSC1; GDSC2 -1.8479 1.5436 -3.8752 8.5219
Capan-2 GDSC1 -0.0441 5.046 -4.3249 8.8618
CFPAC-1 GDSC1 0.6399 4.4779 -3.686 3.6374
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1 -7.4488 -4.7512 -7.486 62.9088
NCI-H28 GDSC1 -6.0457 -4.4842 -6.0532 46.5728
NCI-H2052 GDSC1 -5.5438 -2.1379 -5.8899 41.6886
NCI-H2452 GDSC1 -5.3676 -3.4225 -5.4226 38.3794
IST-Mes1 GDSC1 -4.0673 -0.7159 -4.819 26.7756
MSTO-211H GDSC1 -1.6877 4.6649 -5.3018 19.5236
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 -7.0073 -5.8924 -7.0074 58.558
LNCaP clone FGC GDSC1 -6.7773 -1.1963 -7.5323 53.7339
22Rv1 GDSC1 -6.2055 -2.4364 -6.5295 48.8024
VCaP GDSC1 -5.179 -2.1489 -5.4888 37.3491
DU145 GDSC1 -2.3401 7.2558 -7.1259 29.8134
NCI-H660 GDSC2 0.2164 3.5296 -3.5011 2.5746
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 -5.8167 -3.9308 -5.8455 43.8099
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-375 GDSC1; GDSC2 -8.6471 -7.4054 -8.6471 63.4644
WM35 GDSC1 -8.2209 -5.8882 -8.229 72.07
G-mel GDSC1; GDSC2 -8.1232 -5.4213 -8.145 57.9154
CHL-1 GDSC1 -7.7356 -6.4455 -7.7358 67.583
WM793 GDSC1 -7.4812 -5.3449 -7.4908 63.9142
CP50-MEL-B GDSC1; GDSC2 -6.7313 -4.6523 -6.749 44.3111
Hs 938.T GDSC1; GDSC2 -6.6859 -1.022 -7.4936 45.3725
LOX-IMVI GDSC1 -6.4983 -4.1106 -6.5439 52.0958
IST-MEL1 GDSC1 -6.4649 -4.0957 -6.5102 51.7012
Mel JuSo GDSC1 -6.429 -3.0752 -6.6232 51.1567
SK-MEL-24 GDSC1 -6.1329 -3.4547 -6.2354 47.8086
COLO 679 GDSC1 -6.0535 -3.6191 -6.1273 46.823
A101D GDSC1 -5.9756 -3.989 -6.0069 45.7764
LB373-MEL-D GDSC1; GDSC2 -5.8043 -2.7817 -6.0074 35.8791
UACC-257 GDSC1 -5.6295 -0.1399 -6.6955 44.2702
UACC-62 GDSC1 -5.4863 -1.7922 -5.9332 41.3808
WM278 GDSC1 -5.4483 -3.9189 -5.4638 39.1691
COLO 792 GDSC1 -5.3813 -2.1264 -5.7161 39.8048
MeWo GDSC1 -5.1408 -3.1191 -5.223 35.7203
WM115 GDSC1 -5.0254 -2.0898 -5.3389 35.5534
A-388 GDSC1; GDSC2 -4.9562 -0.0438 -6.0287 31.626
WT2-iPS GDSC1; GDSC2 -4.9559 1.2174 -6.581 33.7476
A2058 GDSC1 -4.9509 -3.5707 -4.9697 32.979
SK-MEL-2 GDSC1 -4.8675 -2.4385 -5.069 33.0374
IGR-37 GDSC1 -4.7331 -2.5063 -4.9054 31.2114
SK-MEL-30 GDSC1; GDSC2 -4.6892 -2.0867 -4.9732 25.2464
SK-MEL-31 GDSC1; GDSC2 -4.6153 -0.2668 -5.5795 28.0279
RPMI-7951 GDSC1 -4.4598 -2.3321 -4.6523 27.9575
IPC-298 GDSC1; GDSC2 -4.4277 -1.3293 -4.951 23.9457
COLO 829 GDSC1 -4.2404 -1.4374 -4.7096 27.0468
Hs 940.T GDSC1; GDSC2 -4.2254 4.4705 -7.4107 33.3478
DJM-1 GDSC1; GDSC2 -4.1068 1.771 -5.996 27.7979
451Lu GDSC1; GDSC2 -4.1061 2.2429 -6.2204 28.7513
A-431 GDSC1; GDSC2 -3.9747 0.8029 -5.4103 24.4848
MZ-MEL-2 GDSC1; GDSC2 -3.9139 0.8101 -5.3539 23.9539
HT-144 GDSC1 -3.7317 2.7562 -6.114 31.6739
LB2518-MEL GDSC1; GDSC2 -3.5855 0.4981 -4.8861 20.153
M14 GDSC1 -3.1716 -0.888 -3.8294 15.3587
COLO 800 GDSC1; GDSC2 -3.1344 4.2642 -6.3144 25.5844
IGR-1 GDSC1 -2.4228 -1.0059 -3.0658 6.242
SH-4 GDSC1 -2.3517 1.0128 -4.0142 13.3497
SK-MEL-5 GDSC1; GDSC2 -2.2389 3.3306 -5.0793 16.7402
WM1552C GDSC1 -2.1945 1.3964 -4.076 13.2385
COLO 783 GDSC1; GDSC2 -2.1677 7.7556 -7.2328 26.0649
SK-MEL-28 GDSC1; GDSC2 -2.1383 2.0758 -4.3697 12.3449
CP66-MEL GDSC1; GDSC2 -2.0799 3.0128 -4.7904 14.6568
GAK GDSC1 -2.0775 -0.2571 -3.1584 5.7625
G-361 GDSC1 -2.0253 7.8466 -7.1612 28.8774
MMAc-SF GDSC1; GDSC2 -1.9868 2.7029 -4.5608 13.0595
MZ-MEL-7 GDSC1; GDSC2 -1.8292 1.5182 -3.8484 8.3075
VMRC-MELG GDSC1; GDSC2 -1.1126 2.8755 -3.9949 7.5114
SK-MEL-3 GDSC1; GDSC2 -0.4471 4.1839 -4.1766 7.2029
RVH-421 GDSC1; GDSC2 -0.4129 3.7199 -3.9389 5.8031
Mel Ho GDSC1; GDSC2 -0.3193 4.1735 -4.0911 6.4837
HMV-II GDSC1 -0.1818 12.1253 -7.8488 25.8165
SK-MEL-1 GDSC1 -0.1749 5.1625 -4.4619 10.0389
EquiPSC Line K2 GDSC1; GDSC2 -4.2673 3.2565 -6.8616 31.7935
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -10.0639 -9.0629 -10.0639 77.6569
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-402 GDSC1 -8.8782 -4.6314 -9.004 73.3823
Rh41 GDSC1 -8.4192 -6.6025 -8.4203 75.2365
HT-1080 GDSC1 -7.7793 -6.0526 -7.7808 67.8475
Rh30 GDSC1 -7.7043 -4.2116 -7.8084 64.4403
KYM-1 GDSC1 -7.5671 -3.2245 -7.8274 61.7692
G-401 GDSC1 -7.234 -6.0081 -7.2342 61.3745
GCT GDSC1 -7.0675 -5.6728 -7.0682 59.2771
VA-ES-BJ GDSC1 -6.9824 -4.545 -7.0152 57.7956
SW982 GDSC1 -6.9436 -4.329 -6.9916 57.2285
Hs 633.T GDSC1 -6.4627 -5.0888 -6.4644 51.7542
SK-LMS-1 GDSC1 -6.4602 -4.6937 -6.4695 51.7044
A-204 GDSC1 -6.1678 -3.7822 -6.2289 48.168
SK-UT-1 GDSC1 -6.0811 -3.4019 -6.188 47.2087
RKN GDSC1 -5.7347 -2.4398 -6.0149 43.6328
TE 441.T GDSC2 -5.3714 0.5645 -6.7191 36.1795
MFH-ino GDSC1 -5.3451 -2.1562 -5.6679 39.3406
RD GDSC1 -5.291 -1.7854 -5.7231 39.1624
MES-SA GDSC1 -5.1063 -2.362 -5.3497 36.1617
SW872 GDSC1 -4.493 -1.0804 -5.1167 30.9755
EW-8 GDSC1 -4.0694 -1.3298 -4.5687 25.1714
Rh18 GDSC1 -3.7056 -2.1057 -3.8962 18.5639
STS-0421 GDSC1; GDSC2 -1.885 0.9946 -3.6316 7.1007
SW684 GDSC1 -0.4936 2.9231 -3.6229 5.1924
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AGS GDSC1 -10.5909 -6.1835 -10.6549 84.648
RERF-GC-1B GDSC1 -8.6872 -3.0151 -9.0922 68.4557
HGC-27 GDSC1 -6.9859 -5.4417 -6.9878 58.2358
NUGC-3 GDSC1 -6.8273 -3.4138 -6.9894 55.41
MKN28 GDSC1 -6.6487 -3.8736 -6.7283 53.7509
TMK-1 GDSC1; GDSC2 -6.2324 -1.0352 -6.9991 41.6316
SK-GT-2 GDSC1 -5.9224 -3.5641 -5.9949 45.2456
MKN1 GDSC1 -5.3142 -1.0401 -6.0093 40.3479
ECC12 GDSC2 -5.1315 -0.3835 -6.0715 32.6431
MKN45 GDSC1 -4.8708 -3.7124 -4.8791 31.9125
Hs 746.T GDSC1 -4.4991 -1.8709 -4.8347 29.3443
SNU-1 GDSC1 -4.3992 1.7295 -6.2616 35.574
SNU-5 GDSC1 -3.6334 3.6352 -6.4535 32.5246
KATO III GDSC1 -3.4868 -0.0456 -4.5332 21.9263
MKN7 GDSC1; GDSC2 -3.4386 -0.7728 -4.1495 15.28
OCUM-1 GDSC1 -3.4122 9.9782 -9.4026 38.6677
23132/87 GDSC1 -3.2321 0.4331 -4.5159 20.6128
HSC-39 GDSC1 -2.3394 0.2493 -3.6221 10.3008
GCIY GDSC1 -2.0502 0.8018 -3.6635 9.6092
IM95 GDSC1 -1.7887 1.0084 -3.5663 8.0239
SCH GDSC1; GDSC2 -1.7205 2.7237 -4.3627 11.1657
Fu97 GDSC1 -1.6774 3.9865 -4.9564 17.4499
NCI-N87 GDSC1 -1.4698 4.2035 -4.9046 16.4528
ECC10 GDSC1 -1.4613 11.7807 -8.6694 31.4428
RF-48 GDSC1 -1.3265 3.27 -4.3379 12.2845
NUGC-4 GDSC1 -1.3072 3.1791 -4.2795 11.822
SNU-16 GDSC1 -0.3792 8.445 -6.1847 20.0551
TGBC11TKB GDSC1 0.6487 11.3711 -6.8786 20.3748
SNG-M GDSC1 -1.9073 6.3056 -6.2952 25.1896
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1 -10.0957 -8.7912 -10.0957 93.3082
B-CPAP GDSC1 -8.9577 -6.5428 -8.963 79.4921
BHT-101 GDSC1 -7.7938 -5.7837 -7.7984 67.7279
CGTH-W-1 GDSC1 -6.9021 -4.5959 -6.9285 56.9234
K5 GDSC1 -6.8753 -3.2041 -7.081 55.7436
8505C GDSC1 -6.7874 -4.3001 -6.8304 55.4798
WRO GDSC1 -5.3526 -2.2838 -5.6399 39.2804
ASH-3 GDSC1 -5.2106 -1.8197 -5.6246 38.1783
FTC-133 GDSC1 -5.1168 -3.089 -5.2021 35.4407
HTC-C3 GDSC1 -4.6389 -3.2911 -4.6663 29.1343
KMH-2 GDSC1; GDSC2 -4.5784 -0.8414 -5.3025 26.4785
TT2609-C02 GDSC1 -4.5509 -2.1678 -4.7983 29.43
CAL-62 GDSC1 -4.3438 0.8262 -5.7873 33.4269
TT GDSC1 -3.2683 1.247 -4.9456 23.578
8305C GDSC1 -2.3476 5.5959 -6.3023 26.7616
ML-1 [Human leukemia] GDSC1; GDSC2 -0.8824 5.1215 -4.9228 12.3052
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHU-022 GDSC1 -8.2806 -5.8266 -8.2913 72.4693
HSC-3 GDSC1 -7.8204 -4.9034 -7.862 66.6453
HSC-4 GDSC1 -7.7176 -5.1828 -7.7389 66.1451
Ca9-22 GDSC1 -7.6984 -5.627 -7.7047 66.5382
FaDu GDSC1 -7.417 -4.3667 -7.486 62.1065
KOSC-2 GDSC1; GDSC2 -7.3778 -3.603 -7.55 50.6594
BICR 22 GDSC1 -7.2341 -5.6186 -7.2359 61.2768
HO-1-u-1 GDSC1 -7.1151 -5.8226 -7.1154 59.8854
PCI-06A GDSC1; GDSC2 -6.6241 -3.8902 -6.7001 43.4285
BICR 78 GDSC1 -6.4994 -3.4857 -6.6241 51.9904
CAL-33 GDSC1 -6.399 -2.928 -6.6217 50.8216
PCI-30 GDSC1 -6.2761 -4.868 -6.2787 49.4291
PCI-38 GDSC1 -6.2614 -3.8655 -6.3186 49.2805
UPCI-SCC-090 GDSC1 -5.7432 -1.5013 -6.3081 44.4012
JHU-029 GDSC1; GDSC2 -5.6644 -1.6865 -6.1611 35.7421
NCI-H3118 GDSC1 -5.6501 -2.6583 -5.868 42.4765
DOK GDSC1 -5.6468 -1.2142 -6.3036 43.629
PCI-04B GDSC1; GDSC2 -5.4992 -2.1284 -5.8441 33.5283
CAL-27 GDSC1 -5.4934 -2.9698 -5.6301 40.3105
HO-1-N-1 GDSC1 -5.4851 -2.275 -5.7869 40.8683
Detroit 562 GDSC1 -5.4501 -3.2093 -5.5409 39.5756
SAS GDSC1 -5.4439 0.5683 -6.7959 43.1908
BICR 10 GDSC1 -5.3951 -3.5969 -5.4325 38.626
JHU-011 GDSC1; GDSC2 -5.2537 -0.1924 -6.2782 34.0618
SCC-25 GDSC1; GDSC2 -5.0921 3.8296 -7.9288 38.0714
SCC-15 GDSC1 -5.0561 4.0347 -7.9914 42.9404
BB30-HNC GDSC1; GDSC2 -5.0272 -1.2384 -5.6277 30.1668
KON GDSC1; GDSC2 -4.7664 1.4712 -6.5058 32.6282
BICR 31 GDSC2 -4.3475 -1.0287 -4.9831 23.77
PE/CA-PJ15 GDSC1; GDSC2 -3.6622 0.2643 -4.8507 20.2439
HSC-2 GDSC1 -3.4748 -0.4489 -4.3338 20.4845
SCC-9 GDSC1 -3.1021 0.9985 -4.67 21.0701
BB49-HNC GDSC1 -2.9281 -0.467 -3.7929 13.9813
OSC-20 GDSC1 -2.8195 1.7409 -4.7816 20.5896
SAT [Human HNSCC] GDSC1 -1.8575 2.7043 -4.4592 14.8111
PCI-15A GDSC1; GDSC2 -1.8369 0.3539 -3.2803 4.7943
SCC-4 GDSC1 -1.3043 4.7829 -5.066 16.9134
BHY GDSC1; GDSC2 -1.2791 2.1189 -3.7448 6.3779
SKN-3 GDSC1 -1.0163 11.5221 -8.1882 28.9938
LB771-HNC GDSC1 -0.949 12.5076 -8.6259 29.9632
OSC-19 GDSC1; GDSC2 0.6581 2.3951 -2.879 0.1809
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
T24 GDSC1; GDSC2 -9.0124 -6.6167 -9.0171 66.6334
CAL-29 GDSC1 -7.8027 -5.2704 -7.8224 67.0989
647V GDSC1 -7.4114 -5.5482 -7.4156 63.3076
SW1710 GDSC1 -7.3464 -5.2036 -7.3576 62.313
KU-19-19 GDSC1 -7.271 -4.9211 -7.2917 61.244
639V GDSC1 -6.4747 -2.5305 -6.7988 51.5381
J82 GDSC1 -6.2652 -4.4524 -6.2789 49.3016
TCCSUP GDSC1 -6.1713 -4.2651 -6.1916 48.1548
UM-UC-3 GDSC1 -6.1439 -2.6505 -6.408 48.1074
RT-112 GDSC1 -5.8708 -3.5937 -5.9362 44.6004
BFTC-905 GDSC1 -5.437 -1.858 -5.8587 40.7536
SW780 GDSC1 -5.0593 -2.9698 -5.1606 34.8205
5637 GDSC1 -4.9142 -3.6914 -4.9247 32.4687
HT-1197 GDSC1 -3.4677 1.6055 -5.3066 26.5996
HT-1376 GDSC1 -0.7919 12.178 -8.3396 28.8087
RT-4 GDSC1 0.2598 3.3771 -3.4159 2.6538
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
C-4-I GDSC1 -8.2399 -5.0102 -8.2915 70.3092
HEY GDSC1 -7.848 -6.0791 -7.8497 68.6312
SW756 GDSC1 -7.714 -3.2607 -7.9793 62.9348
SKN GDSC1 -7.6795 -4.378 -7.7621 64.5076
PWR-1E GDSC1 -7.1262 -4.4927 -7.169 59.3163
C-33 A GDSC1 -6.9158 -4.8818 -6.9287 57.2161
OV17R GDSC1; GDSC2 -6.5178 -3.95 -6.5806 42.3415
SiSo GDSC1 -6.5024 -3.5849 -6.6118 52.0444
HEC-1 GDSC1 -6.497 -4.8867 -6.5019 52.17
OVCA433 GDSC1; GDSC2 -6.4453 -3.4743 -6.5678 41.8277
PA-1 GDSC1 -6.3688 -5.303 -6.3691 50.5862
ME-180 GDSC1 -6.3246 -4.1606 -6.3579 50.0321
CAL-39 GDSC1 -6.2532 -3.7626 -6.3217 49.1897
NEC8 GDSC1 -6.2092 -1.5758 -6.7892 48.9587
PEO1 GDSC1 -6.0292 1.1925 -7.6699 48.0139
JEG-3 GDSC1; GDSC2 -5.8946 -1.2928 -6.5435 38.3889
NT2-D1 GDSC1 -5.8107 -4.0601 -5.8305 43.6997
MS751 GDSC1 -5.7238 -2.3677 -6.0221 43.5604
JAR GDSC1; GDSC2 -5.6648 -2.3582 -5.9603 34.9172
SW954 GDSC1; GDSC2 -5.4933 -3.9111 -5.5107 31.9123
DSH1 GDSC1 -5.2003 -2.5846 -5.3956 37.0503
HeLa GDSC1 -5.0036 -1.2292 -5.6057 36.662
LB831-BLC GDSC1 -4.8816 -2.9195 -4.9778 32.588
OVCA420 GDSC1 -4.8291 -1.9224 -5.1767 33.3967
Ca Ski GDSC1 -4.4871 0.2553 -5.6744 33.7441
SiHa GDSC1 -4.3979 -1.8304 -4.7385 28.1416
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 -4.3481 -1.6599 -4.7437 22.4588
BPH-1 GDSC1 -3.9822 -2.3589 -4.1238 21.6792
UWB1.289 GDSC1; GDSC2 -3.7384 -0.4334 -4.6057 19.1333
SKG-IIIa GDSC1 -3.5059 1.5463 -5.3137 26.8185
ACC-OV7 GDSC1; GDSC2 -3.1298 1.4592 -4.9218 18.7109
TC-YIK GDSC1 -3.106 2.1347 -5.2332 24.5539
OVMIU GDSC1 -2.9149 0.1757 -4.0938 16.1907
HT-3 GDSC1 -1.5942 3.3474 -4.5754 14.7305
JHOS-3 GDSC1; GDSC2 -1.4097 4.2847 -4.8992 13.4625
DoTc2 4510 GDSC1 -1.2394 1.836 -3.5827 6.612
SW962 GDSC1; GDSC2 -0.6806 6.5044 -5.4533 14.6033
KGN GDSC1 -0.0101 12.4904 -7.9009 25.549
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug

References

1 ClinicalTrials.gov (NCT00522834) Elesclomol (STA-4783) With Paclitaxel Versus Paclitaxel Alone in Melanoma. U.S. National Institutes of Health.