Details of the Drug

General Information of Drug (ID: DMCIPP7)

Drug Name

TBAJ-587

Synonyms

TBAJ-587; 2252316-16-6; D6UWM02W81; CHEMBL4529465; (1S,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2-fluoro-3-methoxyphenyl)butan-2-ol; UNII-D6UWM02W81; TBAJ587;TBAJ 587; BCP31090; CQD31616; EX-A1526; BDBM50537220; AC-35636; MS-30728; HY-111747; CS-0090726

Indication

Disease Entry	ICD 11	Status	REF
Tuberculosis	1B10-1B14	Phase 1	[1]

Drug Type

Small molecule

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C30H33BrFN3O5
Canonical SMILES: CN(C)CCC(C1=CC(=NC(=C1)OC)OC)(C(C2=C(C(=CC=C2)OC)F)C3=C(N=C4C=CC(=CC4=C3)Br)OC)O
InChI: InChI=1S/C30H33BrFN3O5/c1-35(2)13-12-30(36,19-16-25(38-4)34-26(17-19)39-5)27(21-8-7-9-24(37-3)28(21)32)22-15-18-14-20(31)10-11-23(18)33-29(22)40-6/h7-11,14-17,27,36H,12-13H2,1-6H3/t27-,30-/m1/s1
InChIKey: JJEGOJPMKLRSPJ-POURPWNDSA-N

Cross-matching ID

PubChem CID: 138319677
ChEBI ID: CHEMBL4529465
TTD ID: DZ31NW

Drug-Molecule Activity Atlas (DMA)^NEW

Click to Jump to the Detailed DMA Information of This Drug

References

1	ClinicalTrials.gov (NCT04890535) Phase 1, Partially Blinded, Placebo-Controlled, Randomized, Combined Single Ascending Dose With Food Effect Cohort Trial and Multiple Ascending Dose Trial to Evaluate the Safety, Tolerability, and PK of TBAJ-587 in Healthy Adults. U.S.National Institutes of Health.