Details of the Drug

General Information of Drug (ID: DMCIY7N)

Drug Name
CRL-8131
Synonyms Flocor; RheothRx; Poloxamer 331; ANX-188; CRL-5861; P-188; Poloxamer-188; RheothRx-pf
Indication
Disease Entry ICD 11 Status REF
Bacterial infection 1A00-1C4Z Phase 3 [1]
Non-small-cell lung cancer 2C25.Y Phase 3 [2]
Sickle-cell disorder 3A51 Phase 3 [3]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C5H10O2
Canonical SMILES
CC1CO1.C1CO1
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChIKey
RVGRUAULSDPKGF-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
24751
ChEBI ID
CHEBI:32026
CAS Number
691397-13-4
UNII
V8B3K56SW0
DrugBank ID
DB11451
TTD ID
D0W0SM
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

References

1 ClinicalTrials.gov (NCT00004408) Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease. U.S. National Institutes of Health.
2 ClinicalTrials.gov (NCT01737814) Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC). U.S. National Institutes of Health.
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)