Details of the Drug

General Information of Drug (ID: DMCKM6D)

Drug Name
NMS-E973
Synonyms NMS-P506; HSP90 inhibitors (cancer), Nerviano; Heat shock protein 90 inhibitors (cancer), Nerviano
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C22H22N4O7
Canonical SMILES
CN1CCC(CC1)NC(=O)C2=NOC(=C2)C3=C(C=C(C=C3OC4=CC=C(C=C4)[N+](=O)[O-])O)O
InChI
1S/C22H22N4O7/c1-25-8-6-13(7-9-25)23-22(29)17-12-20(33-24-17)21-18(28)10-15(27)11-19(21)32-16-4-2-14(3-5-16)26(30)31/h2-5,10-13,27-28H,6-9H2,1H3,(H,23,29)
InChIKey
YLQODGGPIHWTHR-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
135566652
CAS Number
1253584-84-7
TTD ID
D09HVH

References

1 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.