Details of the Drug

General Information of Drug (ID: DMCMDVR)

Drug Name
Triptolide
Synonyms
triptolide; 38748-32-2; Triptolid; PG490; UNII-19ALD1S53J; NSC 163062; CHEMBL463763; CHEBI:9747; 19ALD1S53J; C20H24O6; PG-490; CPD000466307; Triptolide, Tripterygium wilfordii; (-)-Triptolide; PG 490; Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-; SMR000466307; NSC163062; Triptolide, 1; Triptolide(PG490)/; AC1Q6AXN; BSPBio_001595; KBioGR_000315; KBioSS_000315
Indication
Disease Entry ICD 11 Status REF
Autoimmune diabetes 5A10 Phase 3 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 360.4
Logarithm of the Partition Coefficient (xlogp) 0.2
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C20H24O6
IUPAC Name
(1S,2S,4S,5S,7R,8R,9S,11S,13S)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
Canonical SMILES
CC(C)[C@@]12[C@@H](O1)[C@H]3[C@@]4(O3)[C@]5(CCC6=C([C@@H]5C[C@H]7[C@]4([C@@H]2O)O7)COC6=O)C
InChI
InChI=1S/C20H24O6/c1-8(2)18-13(25-18)14-20(26-14)17(3)5-4-9-10(7-23-15(9)21)11(17)6-12-19(20,24-12)16(18)22/h8,11-14,16,22H,4-7H2,1-3H3/t11-,12-,13-,14-,16+,17-,18-,19+,20+/m0/s1
InChIKey
DFBIRQPKNDILPW-CIVMWXNOSA-N
Cross-matching ID
PubChem CID
107985
ChEBI ID
CHEBI:9747
CAS Number
38748-32-2
UNII
19ALD1S53J
DrugBank ID
DB12025
TTD ID
D0I6LH
INTEDE ID
DR1904
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Nuclear factor NF-kappa-B (NFKB) TTSXVID NFKB1_HUMAN ; NFKB2_HUMAN ; TF65_HUMAN ; RELB_HUMAN ; REL_HUMAN Inhibitor [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4)
Main DME 		DE4LYSA CP3A4_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alanine aminotransferase 1 (GPT) OTOXOA0Q ALAT1_HUMAN Gene/Protein Processing [4]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [5]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Gene/Protein Processing [6]
ATP-binding cassette sub-family C member 4 (ABCC4) OTO27PAL MRP4_HUMAN Gene/Protein Processing [6]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Gene/Protein Processing [7]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [6]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [7]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Gene/Protein Processing [8]
Cyclin-A1 (CCNA1) OTX4HD45 CCNA1_HUMAN Gene/Protein Processing [9]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Gene/Protein Processing [9]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Autoimmune diabetes
ICD Disease Classification 5A10
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cytochrome P450 3A4 (CYP3A4) DME CYP3A4 9.85E-01 2.24E-02 7.33E-02
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 149 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -7.1828 -3.9295 -7.2558 36.515
JK1 CTRP2 -5.5522 -3.5798 -5.5788 25.1569
JM1 CTRP2 -6.0571 -3.8382 -6.0848 28.877
OCI-Ly3 CTRP2 -9.4209 -4.9272 -9.5143 51.1371
KMS-20 CTRP2 -9.0586 -1.0691 -9.9192 49.0569
OCI-AML-3 CTRP2; CTRP1 -8.8394 -5.6061 -8.8628 47.3551
JJN-3 CTRP2 -8.3455 -5.0867 -8.3795 44.1109
DB CTRP2 -8.1887 -4.7844 -8.2361 43.1043
NU-DHL-1 CTRP2 -8.1419 -5.2639 -8.1615 42.7278
KHM-1B CTRP2 -8.1188 4.3101 -10.9613 45.4498
KMS-11 CTRP2; CTRP1 -7.9352 -4.9546 -7.964 41.0114
NCO2 CTRP2 -7.926 -4.2554 -8.0085 41.0906
M-07e CTRP2 -7.6911 -4.879 -7.7153 39.7452
KMS-12-BM CTRP2 -7.5085 -4.0041 -7.5944 38.3469
JVM-3 CTRP2 -7.3021 -4.8041 -7.3198 36.7717
Mino CTRP2 -7.2499 -3.6748 -7.3563 37.0601
EoL-1 CTRP2 -7.2341 -6.1149 -7.2341 36.6265
CMK CTRP2 -7.2132 -6.0115 -7.2133 36.4873
SUP-M2 CTRP2 -7.2009 -5.1957 -7.2055 36.4203
EJM CTRP2; CTRP1 -7.1809 -5.6111 -7.1816 36.2741
KO52 CTRP2 -7.1712 -6.4463 -7.1712 36.2071
OPM-2 CTRP2 -7.1403 -4.3096 -7.1785 36.1245
Granta-519 CTRP2 -7.1358 -1.8071 -7.6099 37.3234
NB4 CTRP2 -7.1315 -6.267 -7.1315 35.5788
THP-1 CTRP2; CTRP1 -7.0688 -5.033 -7.0749 35.1818
KMS-26 CTRP2 -7.0629 -4.9637 -7.0705 35.1476
NU-DUL-1 CTRP2; CTRP1 -7.0167 -5.3657 -7.0181 34.8197
MOLT-16 CTRP2 -7.0006 -5.1597 -7.004 34.719
SU-DHL-5 CTRP1 -6.9865 -6.0259 -6.9865 71.9733
MOLT-3 CTRP2 -6.9786 -6.0118 -6.9786 34.9241
HH [Human lymphoma] CTRP2 -6.9455 -5.5251 -6.9459 34.7045
KMS-34 CTRP2 -6.9163 -4.6744 -6.9296 34.1905
NCI-H929 CTRP2 -6.9073 -4.5618 -6.9248 34.1446
L-540 CTRP2 -6.8743 -5.7041 -6.8743 33.8671
Karpas-299 CTRP2 -6.8386 -5.5878 -6.8387 33.6298
SKM-1 CTRP2; CTRP1 -6.8205 -5.7887 -6.8205 33.5092
OCI-AML-2 CTRP2 -6.7699 -5.3253 -6.7706 33.1747
SIG-M5 CTRP2 -6.763 -5.8422 -6.763 33.4872
HL-60 CTRP2 -6.7463 -5.6466 -6.7463 33.3761
KE-97 CTRP2; CTRP1 -6.7296 -4.0662 -6.7297 53.9028
F-36P CTRP2 -6.6886 -2.9007 -6.8734 33.5905
OCI-Ly19 CTRP2 -6.6863 -2.5441 -6.9413 33.7945
GDM-1 CTRP2; CTRP1 -6.6648 -5.1128 -6.6662 32.4774
AML-193 CTRP2 -6.6331 -5.4977 -6.6332 32.6222
Ki-JK CTRP2 -6.6219 -5.1394 -6.6229 32.1904
Pfeiffer CTRP2 -6.6125 -4.8127 -6.6167 32.4986
NOMO-1 CTRP2; CTRP1 -6.6034 -5.2106 -6.6041 32.0665
OCI-M1 CTRP2 -6.5983 -5.2017 -6.5989 32.3918
LP-1 CTRP2; CTRP1 -6.5783 -4.2303 -6.6011 32.3324
Kasumi-2 CTRP2 -6.544 -5.1519 -6.5447 32.0307
OCI-AML-5 CTRP2 -6.5324 -4.9357 -6.5343 31.9573
BCP-1 CTRP2 -6.5271 -3.4208 -6.6195 32.2218
HuT 78 CTRP2 -6.4977 -4.4953 -6.5074 31.752
KM-H2 CTRP2 -6.4767 -4.4282 -6.4887 36.0831
SET-2 CTRP2 -6.4246 -4.6759 -6.4289 31.2471
HD-MY-Z CTRP2 -6.4077 -3.035 -6.5475 31.5843
Kasumi-1 CTRP2 -6.3521 -4.6076 -6.3568 30.7653
GA-10 CTRP2 -6.3292 -4.8329 -6.3308 30.6026
Mono-Mac-1 CTRP2 -6.3205 -4.4362 -6.3291 30.21
KMS-28BM CTRP2 -6.3071 -1.8225 -6.7101 31.4205
KMS-18 CTRP2 -6.2789 -3.8913 -6.3131 30.0187
RPMI-6666 CTRP2 -6.2427 -1.9998 -6.585 31.1555
SU-DHL-8 CTRP2 -6.2335 -3.5916 -6.2915 29.7963
SR CTRP2 -6.2065 -4.3061 -6.2169 29.4572
A3/Kawakami CTRP2 -6.2042 -4.3007 -6.2141 29.7974
U-937 CTRP2; CTRP1 -6.1971 -4.6903 -6.1993 29.367
HEL 92.1.7 CTRP2 -6.1869 -3.1674 -6.2907 29.9969
MV4-11 CTRP2 -6.1523 -4.3806 -6.1594 29.0855
A4/Fukuda CTRP2 -6.1371 -3.8676 -6.1659 29.4135
Daudi CTRP2 -6.1232 -4.7499 -6.1243 29.2284
HuNS1 CTRP2 -6.122 -3.9689 -6.1441 29.2903
EM-2 CTRP2 -6.1033 -5.4196 -6.1033 28.7359
Namalwa CTRP2 -6.0411 -3.6276 -6.0839 28.8213
RPMI-8226 CTRP2; CTRP1 -6.0206 -4.2829 -6.0281 28.2103
SEM CTRP2 -6.0196 -5.0445 -6.0197 28.5347
SU-DHL-6 CTRP2 -6.0027 -2.5844 -6.197 28.723
MOLM-16 CTRP2; CTRP1 -5.9645 -3.8484 -5.9893 27.8945
MM1.S CTRP2 -5.9546 -2.8643 -6.0928 28.2129
SU-DHL-10 CTRP2 -5.9401 -5.0096 -5.9402 27.6495
CML-T1 CTRP2 -5.9336 -3.7247 -5.9655 27.713
ME1 CTRP2 -5.9312 -4.7663 -5.9316 27.5916
KCL-22 CTRP2 -5.9282 -3.0631 -6.0327 27.9226
697 CTRP2 -5.9123 -3.976 -5.9276 27.8704
JURL-MK1 CTRP2 -5.8789 -4.9256 -5.8789 27.2421
P31/FUJ CTRP2 -5.8733 -4.6517 -5.874 27.207
PL21 CTRP2; CTRP1 -5.861 -4.9123 -5.8611 27.1232
Hs 611.T CTRP2 -5.8372 -3.8946 -5.8542 27.3759
L-428 CTRP2 -5.8172 -3.7121 -5.8439 27.275
KYO-1 CTRP2 -5.8111 -3.8212 -5.8321 26.8612
JVM-2 CTRP2 -5.7912 -4.2903 -5.7951 30.7861
PF-382 CTRP2 -5.7899 -4.0287 -5.8007 26.6857
MOTN-1 CTRP2 -5.7543 -4.5377 -5.7551 26.7693
RCH-ACV CTRP2 -5.7124 -3.3591 -5.7658 26.3134
SUP-B15 CTRP2 -5.6766 -4.536 -5.6771 26.2504
HEL CTRP2 -5.6468 -1.8336 -5.9864 26.864
MOLP-2 CTRP2 -5.5981 -3.9291 -5.6081 25.4066
TF-1 CTRP2 -5.5809 -3.3388 -5.6271 25.7668
U266B1 CTRP2 -5.566 -3.5173 -5.5962 25.6133
MHH-CALL-4 CTRP2 -5.5044 -3.773 -5.5184 24.7962
MOLT-13 CTRP2 -5.4709 -3.0024 -5.5525 24.8027
EB1 CTRP2 -5.4675 -2.3193 -5.6653 25.5338
RPMI-8402 CTRP2 -5.4562 -4.4682 -5.4565 24.4295
OCI-Ly10 CTRP2; CTRP1 -5.4022 -1.2758 -5.8718 26.0531
SK-MM-2 CTRP2 -5.3736 -2.8276 -5.4739 24.2194
Ku812 CTRP2; CTRP1 -5.3697 -2.5741 -5.3704 47.6865
LAMA-84 CTRP2 -5.3514 -1.4895 -5.7618 28.9987
KMS-27 CTRP2 -5.3484 -4.4432 -5.3486 23.7118
Ri-1 CTRP2 -5.3367 -1.8497 -5.6437 24.6967
HDLM-2 CTRP2 -5.3025 -3.6031 -5.3187 23.4598
JeKo-1 CTRP2 -5.2733 -4.0442 -5.2753 23.5683
MOLM-6 CTRP2 -5.2481 -3.8125 -5.2546 23.0654
RL CTRP2 -5.227 -2.4939 -5.369 23.7388
Reh CTRP2 -5.1983 -3.5146 -5.216 22.7714
ALL-SIL CTRP2 -5.174 -4.4363 -5.1741 22.5507
RS4;11 CTRP2 -5.1588 -3.4642 -5.2312 16.8839
BV-173 CTRP2 -5.0788 -2.9442 -5.1422 22.1312
Peer CTRP2 -5.0328 -3.3772 -5.0528 21.6773
TALL-1 [Human adult T-ALL] CTRP2 -5.0227 -3.42 -5.0398 21.6005
NALM-6 CTRP2 -5.0113 -2.5966 -5.1222 21.8457
Jurkat CTRP2 -4.9865 -3.0181 -5.0354 24.7792
DEL CTRP2 -4.9447 -3.8416 -4.9465 21.0301
EHEB CTRP2 -4.9258 -3.1699 -4.9567 21.0023
L-363 CTRP2 -4.8886 -1.5099 -5.2512 21.9241
SUP-T1 CTRP2 -4.876 -1.6195 -5.2051 21.7196
Raji CTRP2 -4.8146 -2.7911 -4.8808 20.3825
SU-DHL-1 CTRP2 -4.665 -2.7261 -4.7301 19.3831
WSU-DLCL2 CTRP2; CTRP1 -4.5821 -2.2949 -4.715 19.0671
CA46 CTRP2 -4.4767 -2.2628 -4.6015 18.6826
SUP-T11 CTRP2 -4.4085 -2.0134 -4.5893 18.0819
K-562 CTRP2 -4.3984 -1.9244 -4.5924 18.4065
ST486 CTRP2 -4.3428 -2.1116 -4.4879 17.8626
AMO1 CTRP2; CTRP1 -4.2373 -2.2526 -4.3497 16.7017
HPB-ALL CTRP2 -4.1116 -2.3989 -4.1868 15.7355
Karpas-422 CTRP2 -4.0309 -1.784 -4.2277 15.9709
Ci-1 CTRP2 -3.998 -1.6094 -4.2405 15.9175
BL-70 CTRP2; CTRP1 -3.9883 -2.6759 -3.9883 41.4923
P12-Ichikawa CTRP2 -3.9151 -2.9501 -3.9219 14.1943
SU-DHL-4 CTRP2; CTRP1 -3.8349 -2.1199 -3.9405 14.001
SUP-HD1 CTRP2 -3.7387 -1.9748 -3.8615 13.762
MC116 CTRP2; CTRP1 -3.6908 -2.1133 -3.6908 40.0086
P3HR-1 CTRP2; CTRP1 -3.5857 -0.5768 -3.5907 39.5391
HT CTRP2; CTRP1 -3.4876 -2.0715 -3.4876 39.0797
MHH-CALL-3 CTRP2 -3.0935 3.1796 -5.4278 17.8617
L-1236 CTRP2 -2.2043 7.6542 -6.859 20.9943
MJ CTRP2 -0.4097 9.2061 -6.1456 15.4341
REC-1 CTRP2 0.4895 3.3058 -2.7786 1.3353
Toledo CTRP2 0.6024 11.7005 -6.6198 15.3602
Karpas-620 CTRP2 0.9605 2.4984 -2.2779 0.0912
KMM-1 CTRP2 1.3443 8.8607 -4.7814 7.5564
⏷ Show the Full List of 149 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 -4.7596 -2.8823 -4.8079 20.3021
TE8 CTRP2 -4.6206 -2.5682 -4.7064 19.1591
TE-11 CTRP2 -6.5749 -4.7939 -6.5791 32.2481
TE-5 CTRP2 -6.531 -0.0549 -7.5083 34.8618
OE21 CTRP2 -5.7305 -2.8227 -5.854 27.027
OE33 CTRP2 -5.7022 -3.6557 -5.7282 26.5065
KYSE-30 CTRP2 -5.6907 -1.108 -6.2387 28.2188
KYSE-510 CTRP2 -5.3977 -4.2835 -5.3985 24.3934
KYSE-180 CTRP2 -5.0965 -3.6663 -5.1045 22.0614
TE-9 CTRP2 -4.9902 -3.8143 -4.9929 21.3361
OE19 CTRP2 -4.9162 -1.1709 -5.3761 22.8068
KYSE-70 CTRP2 -4.8753 -2.3491 -5.0221 21.0662
TE-14 CTRP2 -4.7434 -2.7022 -4.8137 20.2698
KYSE-150 CTRP2 -4.7267 -2.1751 -4.8914 20.488
TE-10 CTRP2 -4.1295 -1.5886 -4.4 16.5512
EC-GI-10 CTRP2 -4.1235 -0.1964 -4.8791 18.672
TE-6 CTRP2 -3.9066 -2.0038 -4.3035 9.2393
TE-4 CTRP2 -3.7664 -2.4959 -3.8028 13.3049
KYSE-450 CTRP2; CTRP1 -3.7342 -1.7804 -3.7343 40.3271
TE-1 CTRP2 -3.048 -0.7377 -3.5436 10.2424
KYSE-410 CTRP2; CTRP1 -2.8765 3.3862 -3.2086 36.9689
KYSE-520 CTRP2 -2.8158 2.1229 -4.6261 14.3711
KYSE-140 CTRP2; CTRP1 -2.5535 -0.7989 -2.5536 34.8084
COLO 680N CTRP2 -1.8256 0.1364 -2.7804 4.2535
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 -4.0748 -1.0252 -4.5129 17.1496
Hs 766T CTRP2 -11.1394 1.9358 -13.1922 57.0212
Panc 08.13 CTRP2 -9.8331 -5.9182 -9.8706 53.8256
HuP-T3 CTRP2 -7.0951 -5.3495 -7.0969 35.7061
PSN1 CTRP2 -6.8333 -5.702 -6.8334 33.956
Panc 03.27 CTRP2; CTRP1 -6.3204 -1.7046 -6.339 52.163
MIA PaCa-2 CTRP2 -5.9695 -4.0561 -5.9829 28.2454
Panc 02.03 CTRP2 -5.8641 -3.7771 -5.8884 27.5796
Panc 04.03 CTRP2 -5.8348 -1.2499 -6.351 29.0545
KP-3 CTRP2; CTRP1 -5.7459 -1.2841 -5.7657 49.4114
Capan-1 CTRP2 -5.6502 -2.534 -5.8194 26.6495
DAN-G CTRP2 -5.4982 -3.7217 -5.5135 25.1117
PaTu 8988t CTRP2 -5.2944 -3.7697 -5.3025 23.7295
SNU-213 CTRP2 -5.1394 -3.9655 -5.1414 22.3266
HuP-T4 CTRP2; CTRP1 -5.1143 -3.039 -5.1143 46.5177
PK-59 CTRP2 -5.1128 -1.0335 -5.6468 24.025
Panc 05.04 CTRP2 -4.8378 -1.509 -5.1961 21.5715
PaTu 8988s CTRP2 -4.7384 -0.0799 -5.5775 23.0189
HPAF-II CTRP2 -4.6849 -1.0305 -5.184 21.0726
L3.3 CTRP2 -4.5812 -2.6851 -4.6463 18.8258
SW1990 CTRP2 -4.5006 1.8331 -6.1413 24.3742
SU.86.86 CTRP2 -4.2854 -1.2049 -4.6919 18.0854
KP-4 CTRP2 -4.2047 -1.4519 -4.5239 17.2284
AsPC-1 CTRP2 -4.0649 2.8828 -6.1893 23.3761
Panc 10.05 CTRP2; CTRP1 -4.0501 2.6613 -4.345 42.2504
YAPC CTRP2 -3.6362 -0.4851 -4.2651 14.6346
KP-2 CTRP2 -3.3818 0.3932 -4.3607 14.6737
Capan-2 CTRP2; CTRP1 -3.2851 4.3273 -3.8583 39.3128
CFPAC-1 CTRP2; CTRP1 -3.0229 -0.5635 -3.0245 36.9583
PaTu 8902 CTRP2; CTRP1 -2.8494 2.6136 -3.048 36.5831
PK-45H CTRP2 -2.6689 5.3931 -6.1056 19.7249
TCC-Pan2 CTRP2 -1.7397 3.6237 -4.4523 11.0743
SNU-410 CTRP2 -1.7068 5.6205 -5.4234 14.8851
SUIT-2 CTRP2; CTRP1 -1.5513 3.7019 -1.835 30.8751
QGP-1 CTRP2; CTRP1 -0.8411 5.1769 -1.4125 28.3158
HPAC CTRP2; CTRP1 0.0167 8.303 -1.5754 26.8793
BxPC-3 CTRP2 0.9374 27.7615 -14.3559 30.6988
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 -6.4036 -2.883 -6.569 31.6412
Hs 852.T CTRP2; CTRP1 -7.0208 -4.1381 -7.0211 55.2327
LOX-IMVI CTRP2 -6.8896 -5.3104 -6.8907 34.1869
MeWo CTRP2 -6.3102 -5.1029 -6.3105 30.4713
SK-MEL-1 CTRP2; CTRP1 -6.295 -3.9481 -6.3259 30.1146
WM983B CTRP2 -5.9943 -4.8238 -5.9946 28.3666
IGR-37 CTRP2 -5.8767 -4.9239 -5.8768 27.5825
Hs 944.T CTRP2; CTRP1 -5.757 -3.3793 -5.7571 49.4566
Mel Ho CTRP2 -5.4728 -4.3517 -5.4736 24.5419
COLO 829 CTRP2 -5.4677 -4.1375 -5.4702 24.8653
SK-MEL-3 CTRP2 -5.4617 -3.6489 -5.4795 24.8767
COLO 792 CTRP2 -5.3607 -3.4292 -5.3888 24.2385
WT2-iPS CTRP2 -5.1933 -1.1254 -5.6921 24.7779
Hs 294T CTRP2 -5.176 -3.3135 -5.2048 23.0104
Malme-3M CTRP2 -5.1215 3.3271 -7.4439 30.2211
WM88 CTRP2 -5.0307 -2.7161 -5.1193 22.2468
IGR-1 CTRP2 -5.005 -0.3253 -5.7685 24.4874
RVH-421 CTRP2 -4.9059 -3.9663 -4.9064 21.1156
HT-144 CTRP2 -4.8885 -3.0183 -4.9294 21.1359
SK-MEL-5 CTRP2; CTRP1 -4.8061 -2.8929 -4.8587 20.2794
A-375 CTRP2; CTRP1 -4.6133 -3.4153 -4.6194 18.8389
IPC-298 CTRP2 -4.5979 -2.8124 -4.6474 18.8832
RPMI-7951 CTRP2 -4.5767 -2.9872 -4.6066 18.6756
G-361 CTRP2; CTRP1 -4.5674 -2.8717 -4.5674 44.017
Hs 936.T CTRP2; CTRP1 -4.4775 -2.8841 -4.4775 43.606
WM793 CTRP2 -4.4131 -1.9887 -4.6003 18.1353
Mel JuSo CTRP2 -4.2922 -2.2981 -4.4002 17.0516
SK-MEL-28 CTRP2; CTRP1 -4.2659 -3.0361 -4.2791 16.5507
CJM [Human melanoma] CTRP2 -4.2386 -3.5547 -4.2388 16.6686
UACC-62 CTRP2 -4.1735 -2.5354 -4.2282 16.4195
COLO 741 CTRP2; CTRP1 -4.1362 -0.9384 -4.1414 42.0562
A101D CTRP2 -4.1129 -3.252 -4.1148 15.8367
SK-MEL-30 CTRP2 -4.0674 -2.8309 -4.0866 15.2494
SK-MEL-2 CTRP2 -4.0626 -3.5292 -4.0626 15.4953
K029AX CTRP2 -4.0539 -1.3937 -4.3669 16.5468
WM266-4 CTRP2 -3.8379 -2.8035 -3.8486 14.0339
A2058 CTRP2 -3.7586 -2.7873 -3.7676 13.4998
MDA-MB-435S CTRP2 -3.7369 -2.0655 -3.8458 13.3607
UACC-257 CTRP2 -3.7014 -0.8584 -4.1717 14.7965
COLO 800 CTRP2 -3.6828 -1.9785 -3.7997 13.3688
WM115 CTRP2 -3.6083 -2.3509 -3.6502 12.6107
WM1799 CTRP2 -3.5586 -2.1872 -3.6275 12.0344
HMCB CTRP2 -3.4595 -2.736 -3.463 11.4889
Hs 940.T CTRP2 -3.4149 0.8118 -4.5837 15.6433
Hs 839.T CTRP2 -3.1086 -1.7445 -3.2318 9.5699
SK-MEL-31 CTRP2 -2.8996 -0.852 -3.3408 9.053
Hs 895.T CTRP2 -2.7511 0.146 -3.6158 10.1016
SK-MEL-24 CTRP2 -1.4579 1.9973 -3.3769 6.3733
Hs 688(A).T CTRP2 -1.4169 5.2152 -4.95 12.777
IGR-39 CTRP2 0.3386 6.2016 -4.1383 6.6913
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 -6.2561 -3.2585 -6.3521 30.4314
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 -7.163 -4.7208 -7.1798 36.2074
SK-N-DZ CTRP2 -6.2281 -2.4215 -6.4698 30.73
SK-N-AS CTRP2 -5.7307 -3.2305 -5.7968 26.8323
CHP-126 CTRP2 -5.4928 -1.6329 -5.8741 25.9912
SK-N-BE(2) CTRP2 -5.2236 -1.6266 -5.5728 24.4464
CHP-212 CTRP2 -5.0772 -1.0641 -5.586 24.0474
Kelly CTRP2 -4.1224 -2.1209 -4.2527 16.0004
NH-6 CTRP2 -4.1106 0.1561 -5.01 19.1356
SK-N-FI CTRP2 -3.5911 -1.8009 -3.7434 12.8848
SK-N-SH CTRP2 -3.401 -0.3451 -4.0586 13.5339
KP-N-SI9s CTRP2 -3.3949 -1.4293 -3.6507 11.6214
NB1 CTRP2 -3.2362 -1.8669 -3.3472 10.0388
KP-N-YN CTRP2 -1.6206 4.522 -4.77 12.4443
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-869 CTRP2 -5.8755 -3.5017 -5.9214 27.7283
HuH-28 CTRP2 -5.2632 -1.4022 -5.692 24.6416
SNU-478 CTRP2 -4.7096 -1.1159 -5.1818 21.1373
SNU-1079 CTRP2 -4.2373 -2.6112 -4.2893 16.4921
SNU-308 CTRP2 -3.9349 -2.4286 -3.9921 14.4977
SNU-1196 CTRP2 -1.9301 0.9125 -3.2571 6.4618
HuCC-T1 CTRP2 0.7847 2.3724 -2.297 0.1352
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U2OS CTRP2; CTRP1 -7.1138 -4.0991 -7.1691 35.6394
A-673 CTRP2 -6.9235 -4.5956 -6.9393 34.609
SaOS-2 CTRP2 -6.0064 -3.596 -6.0503 28.5935
SK-ES-1 CTRP2 -5.9755 -3.7368 -6.0068 28.3453
G-292 clone A141B1 CTRP2 -5.873 -2.36 -6.0972 28.3186
SK-N-MC CTRP2 -5.623 -4.1782 -5.6266 25.9037
MHH-ES-1 CTRP2 -5.6208 -3.2834 -5.6771 25.7136
CAL-78 CTRP2 -5.0566 -3.1598 -5.0948 21.8974
TC71 CTRP2 -4.7144 -3.7874 -4.7152 19.8407
SJSA-1 CTRP2 -4.0514 -2.0489 -4.4374 10.2206
HOS CTRP2 -3.6162 -2.2095 -3.6809 12.7418
SW1353 CTRP2 -3.4425 -2.6469 -3.4499 11.0509
Hs 888.T CTRP2 -2.7869 3.6645 -5.3558 17.2009
Hs 822.T CTRP2 -0.0649 5.8261 -4.2319 7.6311
MG-63 CTRP2 0.2089 9.0343 -5.5996 12.455
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 73 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 -6.8418 -5.0738 -6.8446 34.0219
CAL-148 CTRP2 -6.4388 -5.1971 -6.4391 30.9698
HCC38 CTRP2 -6.3104 -4.4203 -6.3188 30.4998
Hs 578T CTRP2 -6.2759 -4.1612 -6.293 30.2988
MDA-MB-453 CTRP2 -6.1212 -5.0521 -6.1213 29.2116
BT-549 CTRP2 -5.8116 -3.1329 -5.8949 27.4294
HCC1806 CTRP2 -5.7951 -4.4607 -5.7967 26.6895
CAL-51 CTRP2 -5.7426 -3.5105 -5.7831 26.4706
MCF-7 CTRP2; CTRP1 -5.6701 -2.0786 -5.9487 26.8069
SK-BR-3 CTRP2 -5.6358 -3.5126 -5.6694 26.0902
MDA-MB-157 CTRP2 -5.3925 -2.9958 -5.4664 24.6059
HCC1500 CTRP2 -5.3363 -3.8869 -5.3419 24.0005
HCC1419 CTRP2 -5.3352 -2.5105 -5.4829 24.4794
HMC-1-8 CTRP2 -5.1649 -3.1371 -5.2111 22.6453
HCC1428 CTRP2 -5.0843 -2.8241 -5.1609 22.5625
AU565 CTRP2 -5.0793 -3.8199 -5.0827 22.2806
HCC1143 CTRP2 -4.9371 -2.524 -5.0551 21.3768
ZR-75-30 CTRP2 -4.8484 -1.1644 -5.3045 22.3441
BT-474 CTRP2 -4.5709 -2.3805 -4.6808 19.2581
MDA-MB-415 CTRP2 -4.2446 -2.2023 -4.362 17.1114
HCC1395 CTRP2 -4.2399 0.5612 -5.3349 20.3831
CAMA-1 CTRP2 -4.1663 -2.2858 -4.2663 16.1857
MDA-MB-468 CTRP2 -4.1043 -2.567 -4.1502 15.9284
ZR-75-1 CTRP2 -3.8741 -1.6342 -4.108 14.7215
EFM-192A CTRP2 -3.8637 -2.8142 -3.8747 14.207
HCC1954 CTRP2 -3.8588 -1.3492 -4.1809 14.944
MDA-MB-231 CTRP2 -3.7073 -0.7501 -4.2347 14.7138
BT-20 CTRP2 -3.6701 -2.2274 -3.7358 13.1046
CAL-85-1 CTRP2 -3.6268 0.4542 -4.6373 16.3997
T-47D CTRP2 -3.4474 3.0246 -5.6594 19.9038
CAL-120 CTRP2 -3.1304 1.3873 -4.5963 14.6609
HDQ-P1 CTRP2 -2.9919 0.0516 -3.8345 11.2506
HCC1569 CTRP2 -2.6048 1.7936 -4.2968 12.2262
MDA-MB-361 CTRP2 -2.5878 3.4854 -5.0871 29.7815
HCC202 CTRP2 -2.5141 1.9523 -4.2635 12.2107
JIMT-1 CTRP2 -2.3697 1.319 -3.8482 9.8539
Hs 578Bst CTRP2 -0.2817 12.3887 -7.6266 19.9386
KPL-1 CTRP2 0.0888 1.0377 -2.088 0.0372
HCC1937 CTRP2 0.5614 16.1599 -8.8855 21.6604
BT 482 CTRP2 -5.9058 -4.3378 -5.91 27.79
BT 416 CTRP2 -5.7829 -4.9561 -5.7829 26.9571
BT 145 CTRP2 -5.5498 -4.1924 -5.5524 25.4125
BT 428 CTRP2 -4.6455 -2.2377 -4.7897 19.8751
BT164 CTRP2 -4.5357 -2.7324 -4.5882 18.8249
BT 286 CTRP2 -4.2084 -1.8494 -4.4043 17.1489
BT 159 CTRP2 -4.1478 -2.4233 -4.2174 16.3
BT 179 CTRP2 -4.0729 -2.7898 -4.0939 15.6342
BT 231 CTRP2 -3.87 -1.0291 -4.2904 15.7252
BT 245 CTRP2 -3.8355 -1.0229 -4.2554 15.4946
BT 139 CTRP2 -3.6369 -1.543 -3.8664 13.4693
BT 440 CTRP2 -3.5265 0.8154 -4.6975 16.3776
BT 422 CTRP2 -3.2869 0.3491 -4.2447 13.9698
BT 112 CTRP2 -3.1791 -1.0955 -3.523 10.8576
BT147 CTRP2 -3.1224 2.2478 -4.9757 16.4864
BT 131 CTRP2 -3.0865 0.2367 -3.9918 12.4511
BT 187 CTRP2 -3.0633 0.5 -4.0895 12.7852
BT 172 CTRP2 -3.0567 1.3945 -4.5036 14.4405
BT 328 CTRP2 -2.8887 0.4111 -3.8754 11.4902
BT 228 CTRP2 -2.6437 -0.0303 -3.4277 9.0757
BT 224 CTRP2 -2.5714 0.9433 -3.8232 10.524
BT 239 CTRP2 -2.5268 2.613 -4.6008 13.62
BT 330 CTRP2 -2.4122 1.2765 -3.8377 10.225
BT 248 CTRP2 -2.3934 3.8249 -5.0822 15.2655
BT 271 CTRP2 -2.1937 -0.4584 -2.7878 5.3858
BT 333 CTRP2 -1.9638 0.6655 -3.1321 6.3181
BT 504 CTRP2 -1.8855 1.6181 -3.5398 7.8692
BT 216 CTRP2 -1.8642 3.966 -4.6951 12.6184
BT 359 CTRP2 -1.435 0.6375 -2.6829 3.4302
BT 232 CTRP2 -1.162 3.3047 -3.7961 7.6016
BT 320 CTRP2 -0.4251 3.3331 -3.2797 4.3463
BT 498 CTRP2 0.6442 2.0209 -2.1782 0.0923
BT 340 CTRP2 0.9271 2.28 -2.1678 0.0538
BT 444 CTRP2 0.965 1.988 -2.0604 0.0094
⏷ Show the Full List of 73 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -5.3189 -4.2107 -5.3198 23.5179
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
42-MG-BA CTRP2 -15.2122 0.0619 -16.9707 68.7338
AM-38 CTRP2 -10.0609 -3.5543 -10.4025 54.3252
D283 Med CTRP2 -6.7271 -5.4468 -6.7273 33.249
U-118MG CTRP2 -5.154 -1.9908 -5.4 23.6183
GMS-10 CTRP2 -5.1121 -3.2506 -5.143 22.5916
SNB-75 CTRP2 -4.8784 -2.6758 -4.9622 21.2157
LN-18 CTRP2 -4.8465 -3.5645 -4.8526 20.3909
Hs 683 CTRP2 -4.8062 -2.0466 -5.0073 21.146
KNS-60 CTRP2 -4.7427 -2.8864 -4.9034 14.2434
ONS-76 CTRP2 -4.6415 -2.2854 -4.7815 19.4873
SF539 CTRP2 -4.364 -1.9203 -4.556 18.1704
LN-229 CTRP2; CTRP1 -4.2761 -0.5575 -4.9157 18.8958
SF268 CTRP2 -4.2656 -1.6829 -4.5114 17.7092
DK-MG CTRP2 -4.2529 -2.6944 -4.2926 16.8971
M059K CTRP2 -4.1242 -3.0193 -4.1328 15.9344
A-172 CTRP2 -4.0813 3.2365 -6.372 24.0484
SNU-466 CTRP2 -3.8905 -2.7811 -3.9059 14.0596
YH-13 CTRP2 -3.6749 -2.4164 -3.7125 13.0392
Daoy CTRP2 -3.6396 -1.7925 -3.8071 12.9231
TM-31 CTRP2 -3.5258 0.0545 -4.3587 15.041
Becker CTRP2 -3.5008 -0.7465 -4.0005 13.5812
CAS-1 CTRP2 -3.4819 -1.9547 -3.5936 11.6749
GaMG CTRP2; CTRP1 -3.4428 1.0724 -3.5074 39.0094
SNU-489 CTRP2 -3.4217 -1.6334 -3.615 11.5691
SW1088 CTRP2 -3.1961 0.6419 -4.31 13.6695
KALS-1 CTRP2 -3.1666 0.0736 -4.0204 12.4355
GB-1 CTRP2 -2.7316 -0.2072 -3.4557 9.0775
CCF-STTG1 CTRP2 -2.6742 -0.2086 -3.3752 8.9388
SNU-1105 CTRP2 -2.6036 -0.9 -3.0135 6.9847
YKG-1 CTRP2 -2.1823 1.7962 -3.8872 9.9332
8-MG-BA CTRP2 -2.1685 -0.6924 -2.6514 4.7671
GOS-3 CTRP2 -2.0553 1.2213 -3.4891 8.0033
SF126 CTRP2 -1.9355 -0.253 -2.6803 4.0547
SNU-626 CTRP2 -1.7335 0.5909 -2.9309 4.7084
SNU-738 CTRP2 -1.6086 2.0047 -3.5356 7.0118
DBTRG-05MG CTRP2 -1.5574 1.4985 -3.2418 5.6873
T98G CTRP2 -1.4998 9.0421 -6.9302 20.0721
KNS-81 CTRP2 -1.082 2.8423 -3.5428 6.1248
U-87MG ATCC CTRP2 -0.9802 2.06 -3.0858 4.087
SW1783 CTRP2 -0.9293 6.1027 -5.0057 12.1074
SF295 CTRP2; CTRP1 -0.7561 6.3369 -1.6771 28.743
U-251MG CTRP2 -0.5566 5.6179 -4.483 9.3967
KNS-42 CTRP2 -0.4348 3.9292 -3.572 5.5297
SNU-201 CTRP2 0.07 8.5976 -5.5239 12.129
NMC-G1 CTRP2 0.4636 2.3483 -2.411 0.4002
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-7 CTRP2 -7.5078 -3.3054 -7.6864 38.9572
HEC-151 CTRP2; CTRP1 -7.4102 -6.2343 -7.4102 37.4341
JHUEM-1 CTRP2 -7.234 -5.823 -7.2343 36.6266
ESS-1 CTRP2 -6.3815 -5.1472 -6.3818 30.9463
JHUEM-2 CTRP2; CTRP1 -5.9913 -4.1192 -6.0034 29.9573
HEC-108 CTRP2; CTRP1 -5.8458 -0.4179 -5.9049 49.8661
HEC-6 CTRP2; CTRP1 -5.8182 -4.9273 -5.8182 52.036
MFE-296 CTRP2 -5.7948 -2.078 -6.0771 27.9989
JHUEM-3 CTRP2 -5.7442 -2.5374 -5.9205 27.2994
RL95-2 CTRP2 -5.6181 -4.2826 -5.6203 25.5136
EN CTRP2 -5.383 -3.0842 -5.4453 24.5033
KLE CTRP2; CTRP1 -5.1891 3.2618 -5.6906 47.2072
HEC-1-B CTRP2 -4.6483 -1.2568 -5.0687 20.5415
HEC-59 CTRP2; CTRP1 -4.4388 -1.1545 -4.444 43.4391
MFE-319 CTRP2; CTRP1 -3.8554 -2.1352 -3.8554 40.8825
AN3-CA CTRP2 -3.4226 -2.0301 -3.5056 11.5168
HEC-265 CTRP1 -3.3815 -2.1156 -3.3815 99.3503
HEC-1-A CTRP2 -3.2838 1.5932 -4.8181 16.2496
EFE-184 CTRP2 -2.677 2.2912 -4.6076 13.6582
HEC-50B CTRP2 -1.4929 2.7599 -3.8195 7.9867
HEC-251 CTRP2; CTRP1 -1.4854 4.2445 -1.8783 32.2324
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 -4.6727 -2.8871 -4.6727 44.4987
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMRC-3 CTRP2 -6.7796 -4.7578 -6.7872 33.6231
TUHR10TKB CTRP2 -5.9517 0.0524 -6.9395 30.9704
CAL-54 CTRP2 -5.3895 -0.557 -6.0979 26.8018
UO-31 CTRP2 -5.3053 1.1058 -6.656 28.4095
SNU-1272 CTRP2 -5.1766 -2.3544 -5.348 23.156
KMRC-1 CTRP2 -5.1532 -2.8185 -5.2353 23.0402
TUHR4TKB CTRP2 -5.0737 -3.6395 -5.0821 21.9107
BFTC-909 CTRP2 -4.6352 -2.6269 -4.7128 19.2279
Caki-1 CTRP2 -3.8678 -0.2005 -4.6078 16.9284
769-P CTRP2 -3.5482 -1.8628 -3.6887 12.2187
786-O CTRP2 -3.2818 0.9098 -4.4961 14.9606
VMRC-RCW CTRP2; CTRP1 -3.0023 3.6476 -3.3973 37.6492
TUHR14TKB CTRP2 -2.9216 3.2823 -5.2913 32.3791
Caki-2 CTRP2 -2.6563 2.2766 -4.5534 13.7143
KMRC-20 CTRP2 -2.5563 0.6476 -3.6921 9.625
RCC10RGB CTRP2; CTRP1 -2.3886 3.1701 -4.7527 13.9362
ACHN CTRP2 -1.947 1.9818 -3.7741 8.9748
VMRC-RCZ CTRP2 -1.732 2.1036 -3.6531 8.0434
OS-RC-2 CTRP2 -1.7166 0.3166 -2.78 4.0428
KMRC-2 CTRP2 1.4834 10.2173 -5.2904 9.4767
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCT 116 CTRP2; CTRP1 -8.2978 -6.4663 -8.2985 43.3437
T84 CTRP2 -7.6169 -3.5689 -7.7625 39.585
CL-34 CTRP1 -7.1826 -4.8742 -7.1968 72.3735
SW403 CTRP1 -7.0126 24.1873 -15.7843 64.581
CW-2 CTRP1 -6.9253 -3.7933 -7.0093 67.3534
HCT 8 CTRP2; CTRP1 -6.7741 -4.8961 -6.7788 33.5771
NCI-H747 CTRP2 -6.2845 -2.2685 -6.5654 31.2313
SNU-407 CTRP2 -6.2673 -4.0818 -6.289 29.8994
RKO CTRP2; CTRP1 -6.1612 -4.7691 -6.1625 29.1252
SNU-175 CTRP2; CTRP1 -6.1492 -2.0123 -6.4878 30.1751
GP2d CTRP2; CTRP1 -6.1215 -4.0397 -6.1215 51.2752
SNU-81 CTRP2; CTRP1 -6.0501 -2.1377 -6.3484 29.3876
SW48 CTRP2; CTRP1 -5.9801 -3.4796 -5.9803 50.4767
SNU-C5 CTRP2; CTRP1 -5.961 -2.1117 -6.2577 28.7937
CCK-81 CTRP2 -5.908 -2.5135 -6.1087 28.1164
LS180 CTRP2; CTRP1 -5.842 -3.6357 -5.8767 27.1127
SNU-C4 CTRP2; CTRP1 -5.6401 -3.4973 -5.6751 26.1235
COLO 320 CTRP2; CTRP1 -5.6384 -1.5025 -6.061 27.4467
SNU-C1 CTRP2 -5.6281 -3.6006 -5.6549 26.0156
LS123 CTRP2; CTRP1 -5.5818 -2.0411 -5.8616 26.2261
HCC-56 CTRP2 -5.4684 -3.3811 -5.5051 24.9854
CL-40 CTRP1 -5.4042 -3.1681 -5.4699 49.4744
LS1034 CTRP2 -5.3286 -0.8018 -5.9467 26.0894
NCI-H508 CTRP2; CTRP1 -5.2423 -2.4271 -5.4042 23.5599
LoVo CTRP2; CTRP1 -5.1392 -2.6328 -5.2539 22.71
HT115 CTRP2; CTRP1 -4.9347 -2.4537 -5.0657 21.4061
MDST8 CTRP2; CTRP1 -4.8937 -3.5539 -4.9011 20.7093
SW948 CTRP2; CTRP1 -4.8651 -0.996 -5.3785 22.6626
DLD-1 CTRP2; CTRP1 -4.7906 -2.1889 -4.7912 45.039
HCT 15 CTRP2 -4.7213 -2.1392 -4.8935 20.4783
SW620 CTRP2; CTRP1 -4.4173 0.6675 -5.5643 21.7266
SNU-61 CTRP2; CTRP1 -4.3684 -1.6898 -4.6311 18.1097
OUMS-23 CTRP2 -4.2808 -2.9395 -4.301 16.6733
SNU-C2A CTRP2; CTRP1 -4.2404 -0.8708 -4.2475 42.5362
CL-11 CTRP2 -4.1024 -0.1327 -4.8998 18.3515
COLO201 CTRP2 -3.9237 -2.176 -4.0252 14.5776
HT-55 CTRP2; CTRP1 -3.8011 -0.8215 -4.3073 15.253
SW480 CTRP1 -3.7248 -0.0465 -4.6033 31.5017
SW1417 CTRP2 -3.7224 -0.2063 -4.4528 15.9339
COLO205 CTRP2; CTRP1 -3.5338 -1.3476 -3.5342 39.2916
LS513 CTRP2; CTRP1 -3.5202 -1.763 -3.5203 39.2289
COLO 678 CTRP2; CTRP1 -3.5093 0.2162 -4.4121 15.2074
RCM-1 [Human ESC] CTRP2; CTRP1 -3.5078 -0.5485 -4.0868 13.9326
NCI-H716 CTRP2 -3.2936 -1.2372 -3.5944 11.4536
SNU-1040 CTRP1 -3.2932 -2.2925 -3.338 19.6103
C2BBe1 CTRP2; CTRP1 -3.0786 4.5356 -3.6845 38.4651
LS411N CTRP2; CTRP1 -2.3844 0.8933 -2.4046 34.081
SNU-503 CTRP2 -2.2133 2.1684 -4.0995 10.8818
KM12 CTRP2; CTRP1 -1.4713 0.6946 -2.7747 3.584
SK-CO-1 CTRP2; CTRP1 -0.3452 6.0666 -1.1418 26.6086
SNU-1033 CTRP2 -0.1794 104.3756 -53.5009 45.2631
HT-29 CTRP2; CTRP1 0.4178 2.2299 -2.3855 0.3668
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 CTRP1 -7.3215 -3.9065 -7.4162 70.8173
SNU-182 CTRP2 -6.0731 -4.9567 -6.0733 28.535
SNU-423 CTRP2 -5.9859 -4.1447 -5.9964 28.3449
HLF CTRP2 -5.4483 -3.1274 -5.5094 24.9343
Hep-G2 CTRP2; CTRP1 -5.0172 -2.6571 -5.1183 21.8511
HuH-6 CTRP2 -4.5134 -2.9241 -4.546 18.2633
JHH-1 CTRP2 -4.4314 -3.7733 -4.4314 17.9524
JHH-2 CTRP2 -4.3741 -2.0598 -4.5337 18.1224
HuH-1 CTRP2 -4.2065 -2.1835 -4.3246 16.8602
SNU-886 CTRP2 -4.0033 -2.8017 -4.022 14.8213
JHH-6 CTRP2; CTRP1 -3.988 -2.4679 -3.988 41.4908
SNU-449 CTRP2; CTRP1 -3.917 -0.27 -3.9318 41.1959
SNU-475 CTRP2 -3.4358 -2.0363 -3.5186 11.6038
PLC/PRF/5 CTRP2 -3.3288 -1.5132 -3.54 11.3546
SNU-761 CTRP2 -3.3044 0.6311 -4.9742 10.661
SNU-387 CTRP2 -3.2391 -1.2455 -3.5326 11.065
SK-HEP-1 CTRP2 -3.2382 -2.6223 -3.2408 10.0112
JHH-4 CTRP2 -3.2284 -2.0548 -3.2901 10.1485
SNU-878 CTRP2 -3.0655 -1.7268 -3.199 8.9855
Hep 3B2.1-7 CTRP2 -1.4331 2.3936 -3.5893 6.9181
JHH-5 CTRP2 -1.2728 2.9377 -3.6996 7.3932
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 160 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DV-90 CTRP2; CTRP1 -8.8968 2.6129 -9.58 60.7752
NCI-H596 CTRP1 -8.3484 -4.8662 -8.4031 80.0547
SCLC-21H CTRP1 -7.9625 -5.9742 -7.9649 82.2377
NCI-H23 CTRP2; CTRP1 -7.3375 -4.034 -7.3382 56.8406
COR-L23 CTRP1 -7.081 -4.9866 -7.0897 71.6517
NCI-H2029 CTRP2; CTRP1 -6.7211 -5.5055 -6.7211 54.0252
NCI-H520 CTRP2 -6.5774 -4.1925 -6.6022 32.3331
DMS 273 CTRP2; CTRP1 -6.525 -3.6434 -6.5254 53.1245
NCI-H211 CTRP2 -6.502 -5.315 -6.5022 31.3898
ChaGo-K-1 CTRP2; CTRP1 -6.4247 -4.763 -6.4247 52.6661
NCI-H1781 CTRP1 -6.2761 -4.8465 -6.2778 61.7551
COR-L51 CTRP2; CTRP1 -6.2643 -2.6221 -6.4674 30.8422
COLO 668 CTRP2; CTRP1 -6.2499 -4.7412 -6.2499 51.8644
NCI-H1963 CTRP1 -6.2444 -3.4968 -6.3222 60.0548
NCI-H522 CTRP2; CTRP1 -6.2183 -3.9998 -6.2184 51.7194
NCI-H2286 CTRP2; CTRP1 -6.185 -0.9217 -6.2285 51.3846
LCLC-97TM1 CTRP2; CTRP1 -6.0909 -3.11 -6.0916 50.9827
HCC1438 CTRP2 -6.0525 -3.8368 -6.08 28.8457
NCI-H1836 CTRP1 -6.0143 -3.901 -6.0418 57.7153
NCI-H841 CTRP2; CTRP1 -5.9705 -3.9846 -5.987 28.2624
RERF-LC-Ad2 CTRP2 -5.9697 -3.7752 -5.9981 28.297
NCI-H1703 CTRP2 -5.8411 -4.0533 -5.8515 27.3796
NCI-H2196 CTRP2 -5.7964 -3.7657 -5.819 27.1231
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 -5.6944 -3.6504 -5.6944 49.1703
COLO 699 CTRP2; CTRP1 -5.6818 -4.4365 -5.6829 25.9339
DMS 53 CTRP2 -5.651 -3.6667 -5.6744 26.157
NCI-H2087 CTRP2 -5.648 -2.7881 -5.7755 26.1383
HCC1359 CTRP1 -5.6464 -4.7488 -5.6465 52.8991
NCI-H810 CTRP2; CTRP1 -5.5971 -3.239 -5.5972 48.8706
NCI-H1092 CTRP2 -5.5448 2.2211 -7.3805 31.3018
NCI-H1755 CTRP2; CTRP1 -5.5288 -3.6687 -5.5489 24.9788
NCI-H2171 CTRP2 -5.4828 -1.2188 -5.9773 26.6709
NCI-H2081 CTRP2; CTRP1 -5.4478 0.1989 -6.4414 28.1426
COR-L105 CTRP2 -5.3469 1.275 -6.7703 28.8969
NCI-H1694 CTRP2; CTRP1 -5.2937 -2.8323 -5.3836 24.003
Lu-99 CTRP2; CTRP1 -5.293 -2.6447 -5.2934 47.3354
NCI-H1734 CTRP2 -5.2921 -3.9089 -5.2968 23.3521
T3M-10 CTRP2; CTRP1 -5.2308 -3.5907 -5.2446 23.3249
NCI-H1568 CTRP2; CTRP1 -5.2235 -3.9061 -5.2235 47.1571
NCI-H1341 CTRP2 -5.1304 -3.0624 -5.1802 22.7776
NCI-H1666 CTRP2; CTRP1 -5.0963 -2.586 -5.0967 46.4363
NCI-H1563 CTRP2 -5.0865 -3.0416 -5.136 22.4843
NCI-H2009 CTRP2; CTRP1 -5.074 -2.8204 -5.0741 46.3337
NCI-H1395 CTRP2 -5.0451 -2.4071 -5.1888 22.5339
PC-14 CTRP2 -5.0264 -3.1289 -5.066 21.7011
Calu-3 CTRP2; CTRP1 -5.0172 39.8082 -21.2915 48.9725
LXF 289 CTRP2; CTRP1 -4.9804 -2.2587 -4.9812 45.9069
NCI-H889 CTRP2 -4.9597 -2.7366 -5.0439 21.4101
SK-MES-1 CTRP2 -4.9258 -2.8506 -4.9883 21.4583
NCI-H1573 CTRP2; CTRP1 -4.9112 -2.6627 -4.9114 45.5896
NCI-H2141 CTRP2; CTRP1 -4.8649 -0.6977 -5.4818 23.0385
HOP-62 CTRP2 -4.8598 -1.1989 -5.3058 22.383
HCC2279 CTRP2 -4.8131 -3.5505 -4.819 20.1679
NCI-H647 CTRP2 -4.8092 -2.2754 -4.9596 20.9866
NCI-H2030 CTRP2; CTRP1 -4.8057 -3.4454 -4.8151 21.5144
HCC15 CTRP2; CTRP1 -4.798 0.4146 -5.8558 23.8578
NCI-H322 CTRP2 -4.7478 -2.3623 -4.8756 20.4988
NCI-H1651 CTRP2 -4.7166 -2.5804 -4.8034 20.1481
NCI-H2172 CTRP2; CTRP1 -4.7129 -1.7824 -4.9811 20.4177
LK2 CTRP2 -4.656 -2.6312 -4.7305 19.7022
NCI-H146 CTRP2 -4.6444 -1.7555 -4.9049 20.2813
SK-LU-1 CTRP2; CTRP1 -4.6354 -2.2175 -4.7893 19.4954
NCI-H441 CTRP2; CTRP1 -4.6328 -0.9634 -5.1507 20.7974
NCI-H1581 CTRP2 -4.6136 -2.6358 -4.6882 19.0741
HCC1833 CTRP2; CTRP1 -4.6 -2.2569 -4.7424 19.2198
HCC2108 CTRP2; CTRP1 -4.5657 -2.0023 -4.7633 20.5054
MOR/CPR CTRP2 -4.4901 -3.5717 -4.4913 18.0026
HCC4006 CTRP2; CTRP1 -4.477 -1.3859 -4.83 19.504
RERF-LC-MS CTRP2 -4.4759 -2.772 -4.5199 18.3975
NCI-H1975 CTRP1 -4.4705 4.0141 -5.0752 81.4105
NCI-H1915 CTRP2; CTRP1 -4.4199 0.7738 -4.5041 43.6077
NCI-H2085 CTRP2 -4.3622 -0.4726 -5.0401 19.6076
Sq-1 CTRP2; CTRP1 -4.3244 -2.2255 -4.4498 17.3266
NCI-H1184 CTRP2 -4.3112 -2.486 -4.3871 17.0662
NCI-H650 CTRP2; CTRP1 -4.248 -2.0965 -4.2481 42.5567
NCI-H1944 CTRP2; CTRP1 -4.2338 0.2548 -4.2766 42.6961
NCI-H3255 CTRP1 -4.2123 -2.0464 -4.3922 33.6411
NCI-H661 CTRP2; CTRP1 -4.2 -1.2796 -4.2025 42.3424
NCI-H2228 CTRP2 -4.1769 -0.3366 -4.8963 18.544
KNS-62 CTRP2; CTRP1 -4.1514 -2.4818 -4.1514 42.2399
NCI-H82 CTRP1 -4.141 -2.4601 -4.141 99.4004
RERF-LC-KJ CTRP1 -4.1312 -1.1842 -4.134 67.1779
EPLC-272H CTRP2; CTRP1 -4.0999 -2.1881 -4.1 41.8797
NCI-H1155 CTRP2 -4.0994 -1.3953 -4.4272 16.5613
NCI-H2106 CTRP2 -4.0599 -0.8631 -4.5691 16.9756
HCC33 CTRP1 -4.0403 -1.2068 -4.0426 96.7122
NCI-H1437 CTRP1 -4.032 -1.6206 -4.0326 97.8283
EBC-1 CTRP2; CTRP1 -4.028 1.5853 -4.1698 41.8012
EKVX CTRP2 -3.9897 0.4447 -5.0065 18.795
VMRC-LCD CTRP2; CTRP1 -3.9522 -0.6974 -3.9589 41.3407
NCI-H2170 CTRP2 -3.8938 -1.8406 -4.0633 14.9607
NCI-H1623 CTRP2 -3.8899 -2.2413 -3.9705 14.6203
DMS 454 CTRP2 -3.8554 5.5418 -7.2638 26.3083
NCI-H2073 CTRP1 -3.8114 -2.501 -3.8613 27.0482
NCI-H2291 CTRP2 -3.805 0.5287 -4.8729 17.45
NCI-H2110 CTRP2; CTRP1 -3.7993 -1.1147 -4.1838 15.1221
NCI-H446 CTRP2 -3.7712 -2.6981 -3.7877 13.2694
NCI-H1048 CTRP1 -3.7651 -1.7816 -3.7652 98.3943
NCI-H1876 CTRP1 -3.7417 -1.456 -4.0578 28.0186
LUDLU-1 CTRP2 -3.7243 -1.5359 -3.9639 14.087
SW1271 CTRP2 -3.7166 0.0028 -4.5533 15.9705
NCI-H838 CTRP2 -3.6999 -2.3928 -3.7422 13.2219
NCI-H1339 CTRP2 -3.6891 -1.8423 -3.8396 13.5306
NCI-H196 CTRP2 -3.6878 -1.7476 -3.8721 13.3038
NCI-H2126 CTRP2; CTRP1 -3.6706 -2.7455 -3.6706 39.9165
NCI-H1105 CTRP2; CTRP1 -3.6608 -2.5697 -3.681 12.8863
HCC827 CTRP2; CTRP1 -3.6398 -2.3479 -3.688 13.3627
NCI-H460 CTRP2; CTRP1 -3.6394 -1.319 -3.9531 13.4576
COR-L279 CTRP1 -3.6216 -2.112 -3.6216 99.1839
NCI-H1869 CTRP2 -3.5763 -1.3104 -3.8751 13.3222
NCI-H358 CTRP2; CTRP1 -3.566 2.8468 -3.8551 39.9735
NCI-H292 CTRP2 -3.5361 -1.5758 -3.7572 12.4304
HCC78 CTRP2; CTRP1 -3.5201 -1.61 -3.5202 39.2282
LC-1/sq-SF CTRP2; CTRP1 -3.5163 3.3126 -3.887 40.0022
NCI-H2122 CTRP2; CTRP1 -3.513 -0.5784 -4.0973 13.6501
NCI-H2444 CTRP2 -3.4857 -1.6162 -4.0463 6.9762
Calu-1 CTRP2 -3.4633 1.773 -5.0782 17.7165
NCI-H526 CTRP2 -3.4554 -1.5154 -3.6883 11.9376
CAL-12T CTRP2; CTRP1 -3.4435 -0.2171 -4.176 13.7701
HCC95 CTRP2 -3.4087 -0.753 -3.9166 12.6674
HCC44 CTRP2; CTRP1 -3.4064 5.3376 -4.2571 40.1406
DMS 79 CTRP2 -3.2939 0.7197 -4.4431 14.446
NCI-H1299 CTRP2; CTRP1 -3.2681 -1.6984 -3.2682 38.0761
HCC1195 CTRP2; CTRP1 -3.2484 -0.6458 -3.7916 11.7472
COR-L95 CTRP2 -3.2087 0.1688 -4.0844 13.1316
NCI-H1373 CTRP2; CTRP1 -3.1749 0.9285 -3.2198 37.7473
LCLC-103H CTRP2; CTRP1 -3.1727 -1.4034 -3.1727 37.6397
SBC-5 CTRP2 -3.1724 -2.7679 -3.1726 9.2288
NCI-H1930 CTRP1 -3.1671 12.0713 -6.4734 54.7349
SHP-77 CTRP2; CTRP1 -3.1551 -1.8619 -3.1551 37.5592
NCI-H226 CTRP2 -3.0849 0.7095 -4.2316 13.0801
HCC366 CTRP2 -3.0662 0.0825 -3.9232 11.7929
HCC1588 CTRP2 -3.0099 -1.9642 -3.0775 8.3796
NCI-H1650 CTRP2 -2.974 -0.6216 -3.5161 9.9378
NCI-H1792 CTRP2; CTRP1 -2.9359 -0.0195 -2.9423 36.5714
LOU-NH91 CTRP2 -2.8437 -0.6272 -3.3795 9.0574
NCI-H2405 CTRP2; CTRP1 -2.7895 5.947 -3.7644 37.7255
Calu-6 CTRP2; CTRP1 -2.7836 1.4725 -2.8501 36.0075
NCI-H2023 CTRP2; CTRP1 -2.705 0.1166 -3.5806 9.5186
NCI-H1355 CTRP2; CTRP1 -2.6625 2.7329 -2.8655 35.7452
RERF-LC-A1 CTRP2 -2.5558 -0.9725 -2.9327 6.5406
NCI-H1693 CTRP2 -2.4888 1.4064 -3.9721 10.9516
COR-L88 CTRP1 -2.3885 15.3122 -7.0945 61.8349
NCI-H1435 CTRP2; CTRP1 -2.3604 7.1395 -3.6884 36.5068
A-549 CTRP2; CTRP1 -2.2581 -0.001 -2.2597 33.4613
HOP-92 CTRP2 -2.1347 3.5469 -4.7173 25.715
NCI-H2342 CTRP2; CTRP1 -2.0388 0.5501 -3.1409 6.5115
HCC2935 CTRP2; CTRP1 -1.9499 1.2553 -3.414 7.4717
NCI-H727 CTRP2; CTRP1 -1.7745 3.7867 -2.0938 31.9689
Lu-65 CTRP2; CTRP1 -1.667 9.4056 -3.7985 35.1153
IA-LM CTRP2 -1.5085 2.6814 -3.7588 8.064
NCI-H1793 CTRP2; CTRP1 -0.7316 11.2619 -3.6034 32.7005
DMS 114 CTRP2 -0.4943 25.7349 -14.4515 32.9501
SW1573 CTRP2 -0.0347 7.2568 -4.944 10.1018
NCI-H1838 CTRP2 0.0624 26.5348 -14.4369 31.9998
RERF-LC-Ad1 CTRP2 0.2674 14.9309 -8.5008 21.168
HCC1171 CTRP2 0.4249 8.7974 -5.3674 11.0006
NCI-H69 CTRP2 0.5266 7.4668 -12.0766 1.4872
BEN CTRP2; CTRP1 2.4664 8.5463 0.8651 16.0259
Hs 888.Lu CTRP2 -2.7059 1.4657 -4.2034 12.3961
⏷ Show the Full List of 160 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 -5.6585 -4.2529 -5.6613 26.1375
SYO-1 CTRP2 -5.5706 0.4949 -6.6876 29.3196
H-STS CTRP2 -4.7866 -3.5981 -4.7905 20.3321
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -5.4812 -4.1403 -5.4838 24.9556
A2780 CTRP2; CTRP1 -7.1669 -4.4835 -7.1964 35.9103
OVCAR-4 CTRP2; CTRP1 -7.1096 -3.8836 -7.1858 35.6771
JHOS-4 CTRP1 -7.0018 1.7647 -7.3723 74.8331
JHOC-5 CTRP2; CTRP1 -6.7406 -4.497 -6.7565 33.0299
COV434 CTRP2; CTRP1 -6.5432 -4.2135 -6.5657 32.0979
SNU-119 CTRP2 -6.4081 -2.7189 -6.6096 31.4321
RMUG-S CTRP1 -6.1966 -3.534 -6.267 59.5631
Caov-3 CTRP2; CTRP1 -6.1743 -4.2819 -6.1848 29.2429
OAW42 CTRP1 -6.0448 -5.3299 -6.0448 58.5915
OV56 CTRP2 -5.8195 -4.6113 -5.8202 27.2034
TYK-nu CTRP2; CTRP1 -5.6535 -2.6857 -5.7995 26.2385
OVKATE CTRP1 -5.602 -1.792 -5.9784 51.7333
OVK18 CTRP2; CTRP1 -5.5952 -3.2339 -5.6556 25.5574
OC 314 CTRP2 -5.4786 -3.5904 -5.5004 25.0028
TOV-112D CTRP2 -5.4768 -3.8337 -5.4868 24.9512
COV362 CTRP2; CTRP1 -5.3883 -1.3574 -5.8316 25.8689
TOV-21G CTRP2 -5.3314 -2.2303 -5.5368 24.655
MCAS CTRP2 -5.3022 -3.0691 -5.3641 23.6127
OVTOKO CTRP2 -5.2517 -1.4249 -5.6726 24.5376
COV644 CTRP2; CTRP1 -5.1951 -3.1114 -5.2433 23.2033
OVISE CTRP2 -5.0322 -3.7469 -5.0367 21.6214
OV7 CTRP2; CTRP1 -4.9997 -0.2489 -5.7915 24.5538
OAW28 CTRP2 -4.7883 -1.9446 -5.0127 21.0189
JHOM-1 CTRP2; CTRP1 -4.4171 -2.3137 -4.527 18.2335
DOV13 CTRP2 -4.3006 -0.6753 -4.8972 18.8957
RMG-I CTRP2; CTRP1 -4.2926 -0.041 -5.1376 19.7807
OVMANA CTRP1 -4.2038 -3.6098 -4.2038 68.0595
SNU-840 CTRP2; CTRP1 -3.7937 -0.6264 -4.3751 15.4908
OVSAHO CTRP2 -3.7809 -1.4383 -4.0671 14.2942
IGROV-1 CTRP2; CTRP1 -3.7711 -0.0191 -4.6005 16.2998
OVCAR-8 CTRP2; CTRP1 -3.5713 -2.13 -3.6523 12.161
SNU-8 CTRP2 -3.5211 -2.0822 -3.6077 11.8469
ONCO-DG-1 CTRP2 -3.2284 -0.8117 -3.7025 11.3473
OVCAR-5 CTRP2 -3.1507 1.2989 -4.5494 14.8519
EFO-27 CTRP2; CTRP1 -3.0653 1.8002 -4.7059 15.2752
OV-90 CTRP2; CTRP1 -2.6323 -0.2465 -3.3159 8.5955
Kuramochi CTRP2 -2.5373 1.111 -3.9 10.4394
JHOS-2 CTRP2 -2.2577 3.969 -5.0347 14.7886
ES2 CTRP2 -1.7147 0.7237 -2.9818 4.8865
HEY A8 CTRP2; CTRP1 -1.3326 4.8016 -1.8478 30.4082
FU-OV-1 CTRP2 -1.0634 10.6183 -7.3967 20.4205
SK-OV-3 CTRP2; CTRP1 0.0691 9.7115 -2.1059 27.9749
EFO-21 CTRP2; CTRP1 0.6757 11.446 -2.2539 27.1749
COV318 CTRP1 1.5082 26.2202 -8.6093 43.024
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 -4.8345 -3.2361 -4.8548 20.7063
KYM-1 CTRP2 -6.4147 -3.7617 -6.4639 31.3307
A-204 CTRP2 -6.3673 -2.1246 -6.6898 31.9109
G-401 CTRP2; CTRP1 -6.3383 -4.0141 -6.3384 52.2695
TE 617.T CTRP2 -6.0743 -4.0899 -6.089 28.9476
BT-16 CTRP2 -6.0722 -3.902 -6.0964 28.9656
BT-12 CTRP2 -6.0416 -5.3935 -6.0416 28.6807
Tm87-16 CTRP2 -6.0267 -4.758 -6.0274 28.5837
Rh41 CTRP2 -5.943 -4.7783 -5.9434 27.6698
HT-1080 CTRP2; CTRP1 -5.6793 -2.9649 -5.7769 26.5974
TTC-709 CTRP2 -5.6681 -1.8418 -5.999 27.3271
GCT CTRP2 -5.663 -4.4143 -5.6642 26.1624
SW982 CTRP2 -5.4547 -4.7311 -5.4547 24.7703
Hs 729.T CTRP2 -5.1549 -2.272 -5.3357 23.3947
G-402 CTRP2 -5.1479 -2.7217 -5.2441 23.0537
RD CTRP2 -5.0149 -1.2549 -5.4567 23.3946
RKN CTRP2; CTRP1 -3.9218 -1.2809 -4.272 15.4658
SK-UT-1 CTRP2 -3.1391 6.2095 -6.9317 23.5689
SK-LMS-1 CTRP2 -2.9716 0.2106 -3.8647 11.6523
Rh18 CTRP2 -1.9105 -0.4792 -2.5457 3.4395
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 -0.8541 4.348 -4.0787 8.2466
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2052 CTRP1 -6.7211 6.4609 -8.2055 79.3644
NCI-H28 CTRP2; CTRP1 -6.1589 -4.896 -6.1589 51.2943
MSTO-211H CTRP2; CTRP1 -5.4142 -1.5158 -5.4239 47.8983
IST-Mes1 CTRP2 -5.3664 -0.893 -5.9567 26.2399
JL-1 CTRP2 -4.9044 -2.5267 -5.0146 21.4803
MPP 89 CTRP2 -4.8281 -2.929 -4.8751 20.7541
NCI-H2452 CTRP2 -3.6742 -1.7525 -3.8559 13.2043
ACC-MESO-1 CTRP2 -1.893 1.0942 -3.3161 6.6352
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 -5.5286 -2.9528 -5.6175 25.5641
VCaP CTRP2 -5.3252 -3.3982 -5.3541 24.0047
22Rv1 CTRP2 -4.5893 -3.1796 -4.6053 18.7125
NCI-H660 CTRP2 -4.1526 7.989 -8.7353 30.851
PaCa-3 CTRP2; CTRP1 -3.3427 0.2124 -3.3606 38.5704
DU145 CTRP2 -1.9216 1.8359 -3.6795 8.5274
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 -6.5237 -4.9607 -6.5254 31.8989
YD-15 CTRP2 -4.4282 -3.3312 -4.4332 17.6033
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 -7.5894 -5.194 -7.5995 39.0254
NUGC-3 CTRP2 -6.8687 -4.3283 -6.8968 33.9227
SNU-216 CTRP2 -6.8069 -1.3845 -7.3701 35.4725
AGS CTRP2; CTRP1 -6.3223 -5.1293 -6.3226 30.1942
SNU-5 CTRP2 -6.3105 -4.7168 -6.3134 30.1244
IM95 CTRP2 -6.1532 -3.5223 -6.2116 29.6203
SNU-668 CTRP2 -5.6519 -4.6718 -5.652 25.7314
SNU-1 CTRP2 -5.611 -2.0866 -5.8747 26.7159
NCC-StC-K140 CTRP2 -5.6095 -2.7872 -5.7297 26.21
GSS CTRP2 -5.5755 -2.3316 -5.7863 25.9443
HGC-27 CTRP2 -5.4655 -2.896 -5.5582 25.1566
Hs 746.T CTRP2 -5.1682 -2.4868 -5.3068 23.3358
HuG1-N CTRP2 -5.0361 -3.4642 -5.0502 22.0287
SNU-601 CTRP2 -4.7223 -1.2891 -5.1275 21.323
23132/87 CTRP2 -4.604 -3.5734 -4.6063 18.7643
NCI-N87 CTRP2 -4.5137 -1.5205 -4.8393 19.3026
SNU-719 CTRP2 -4.2881 -2.4038 -4.3762 18.1204
SNU-620 CTRP2 -4.2031 -2.1688 -4.3301 16.5255
Fu97 CTRP1 -4.0784 -2.3842 -4.0784 99.3314
SH-10-TC CTRP2; CTRP1 -4.053 -2.7852 -4.053 41.7887
ECC10 CTRP2 -4.0523 -2.6263 -4.0907 15.2143
NUGC-4 CTRP2; CTRP1 -3.9332 -0.9716 -3.9366 41.1244
ECC12 CTRP2 -3.5818 -2.1968 -3.6509 12.1896
GSU CTRP2 -3.3723 -2.9183 -3.3725 10.5594
MKN74 CTRP2; CTRP1 -3.3607 1.9497 -3.5047 38.7912
LMSU CTRP2 -2.6165 0.2052 -3.5119 9.3527
KATO III CTRP2 -1.2391 0.8762 -2.6555 2.9997
MKN7 CTRP2; CTRP1 -0.8756 6.4063 -1.8299 29.4359
MKN1 CTRP2 -0.1668 2.8905 -2.9523 2.5174
MKN45 CTRP2 0.882 2.1243 -2.1803 0.0335
KE-39 CTRP2 1.6537 13.3696 -6.6852 13.9863
SNU-685 CTRP2 -4.3233 -1.9787 -4.4974 17.8356
SNG-M CTRP2; CTRP1 -2.8362 1.873 -2.9413 36.3296
SNU-1077 CTRP2 -0.7235 3.1193 -3.4194 5.0606
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8305C CTRP2 -5.2787 -3.8147 -5.2858 23.271
BHT-101 CTRP2 -5.0792 -1.7961 -5.3772 22.9566
B-CPAP CTRP2 -4.5922 -3.3764 -4.5991 18.7013
ML-1 [Human leukemia] CTRP2 -4.5056 -0.7708 -5.0821 20.174
SW579 CTRP2 -4.3647 -3.298 -4.369 17.5222
FTC-238 CTRP2 -4.1099 1.091 -5.4127 20.665
TT CTRP2 -4.0596 -2.8905 -4.0742 15.1824
8505C CTRP2 -3.6274 -1.5441 -3.8665 13.1024
TT2609-C02 CTRP2 -2.9123 2.3732 -4.8383 15.4478
FTC-133 CTRP2 -2.7096 -0.7763 -3.1567 8.1571
CGTH-W-1 CTRP2 -2.4788 -0.3415 -3.1438 7.1959
CAL-62 CTRP2 0.4544 2.2636 -2.3833 0.3493
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FaDu CTRP2 -5.915 -4.6379 -5.9159 27.8406
HSC-2 CTRP2; CTRP1 -5.8087 -4.8843 -5.8087 49.841
BICR 56 CTRP2 -5.7992 -2.0145 -6.0976 28.083
SCC-4 CTRP2 -5.7626 -2.4266 -5.963 27.5045
BICR 6 CTRP2 -5.7491 -3.8159 -5.7673 26.7929
CAL-27 CTRP2 -5.5636 -2.7651 -5.684 25.9056
PE/CA-PJ49 CTRP2 -5.5417 -3.8035 -5.5545 25.393
SNU-1214 CTRP2 -5.5107 -3.4628 -5.5444 24.9046
BICR 22 CTRP2 -5.4749 -3.546 -5.4994 24.9873
SNU-1066 CTRP2 -5.3406 -3.8105 -5.349 23.6874
CAL-33 CTRP2 -5.2995 -4.0348 -5.3019 23.7445
PE/CA-PJ34 (clone C12) CTRP2 -5.0716 -3.353 -5.0933 22.291
SCC-25 CTRP2 -5.0269 -2.5695 -5.1439 21.9706
BICR 16 CTRP2 -4.9945 -2.9759 -5.046 21.8781
BHY CTRP2 -4.9597 -3.3064 -4.9815 21.1973
HSC-3 CTRP2 -4.7303 -3.9507 -4.7305 19.5979
Detroit 562 CTRP2 -4.6577 -1.5928 -4.9748 20.2276
SNU-1076 CTRP2 -4.3022 -2.4558 -4.3824 17.0214
YD-10B CTRP2 -4.2899 -2.7243 -4.3311 16.8051
BICR 18 CTRP2 -3.9009 -1.7335 -4.0995 15.1125
SNU-899 CTRP2 -3.7147 -2.1873 -3.7964 13.1173
SCC-9 CTRP2; CTRP1 -3.6885 -1.2496 -4.0173 14.1789
BICR 31 CTRP2 -3.6239 -1.4669 -3.8759 13.4655
PE/CA-PJ15 CTRP2 -3.5761 -0.1763 -4.3123 14.9931
PE/CA-PJ41 (clone D2) CTRP2 -3.4196 2.3036 -5.2872 18.421
HSC-4 CTRP2 -3.0788 -0.8468 -3.5307 10.275
YD-8 CTRP2 -3.0543 0.3323 -4.0259 12.1754
SNU-1041 CTRP2 -2.9494 0.2462 -3.8818 11.3354
SNU-46 CTRP2 -2.4166 3.2779 -4.8609 14.1164
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 CTRP2 -6.4318 -4.1627 -6.4535 31.3532
647V CTRP2 -5.563 -2.0181 -5.8392 26.4409
253J CTRP2 -5.5028 -3.3762 -5.5435 24.8758
JMSU-1 CTRP2 -5.2545 -4.0447 -5.2566 23.0932
SW1710 CTRP2 -4.8407 -2.7931 -4.9084 20.5615
J82 CTRP2 -4.6385 0.344 -5.6416 22.9683
RT-4 CTRP2; CTRP1 -4.5888 -3.2283 -4.5888 44.115
BC-3C CTRP2 -4.5333 -2.6421 -4.5977 18.8498
RT-112 CTRP2 -4.4645 -3.5005 -4.4664 17.8344
5637 CTRP2; CTRP1 -4.4569 -2.4592 -4.457 43.5121
SCaBER CTRP2 -4.3892 -2.7145 -4.4348 17.8252
KMBC-2 CTRP2; CTRP1 -3.8035 0.4671 -3.8438 40.7261
UM-UC-1 CTRP2 -3.7706 -1.689 -3.9696 14.2476
U-BLC1 CTRP2 -3.6478 -1.1208 -4.018 14.0634
KU-19-19 CTRP2 -3.3459 -2.7866 -3.347 10.3868
CAL-29 CTRP2 -3.3208 -1.0774 -3.6965 11.5805
639V CTRP2 -3.1716 -1.0465 -3.549 10.6005
TCCSUP CTRP2 -2.9983 0.2473 -3.9308 11.6539
BFTC-905 CTRP2 -2.9857 -0.1589 -3.7326 10.827
VM-CUB-1 CTRP2 -2.44 1.3442 -3.9247 10.3251
HT-1376 CTRP2; CTRP1 -2.3335 1.1175 -2.3616 33.8661
UM-UC-3 CTRP2; CTRP1 -1.7479 4.5238 -2.2306 32.2084
T24 CTRP2 -1.0151 6.5998 -5.3201 13.4802
253J-BV CTRP2 0.7313 2.7033 -2.4347 0.351
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 -4.3504 -3.8575 -4.3504 17.338

References

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