Details of the Drug

General Information of Drug (ID: DMCQRS2)

Drug Name
RG7414
Indication
Disease Entry ICD 11 Status REF
Colorectal cancer 2B91.Z Discontinued in Phase 2 [1]
Non-small-cell lung cancer 2C25.Y Discontinued in Phase 2 [1]
Cross-matching ID
TTD ID
D01AFG
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Epidermal growth factor-like protein 7 (EGFL7) TT7WD0H EGFL7_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Colorectal cancer
ICD Disease Classification 2B91.Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Epidermal growth factor-like protein 7 (EGFL7) DTT EGFL7 2.56E-01 0.07 0.33
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030998)
2 Anti-EGFL7 antibodies enhance stress-induced endothelial cell death and anti-VEGF efficacy. J Clin Invest. 2013 September 3; 123(9): 3997-4009.