Details of the Drug

General Information of Drug (ID: DMCU5LD)

• Drug Name: Lonidamine
• Synonyms: DICA; Doridamina; Lonidamin; Lonidamina; Lonidaminum; Dichlondazolic acid; Diclondazolic acid; AF 1890; L 4900; AF-1890; Doridamina (TN); KN-228; Lonidamina [INN-Spanish]; Lonidamine (INN); Lonidamine [BAN:INN]; Lonidaminum [INN-Latin]; TH-070; 1-(2,4-Dichlorbenzyl)-indazole-3-carboxylic acid; 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid; 1-(2,4-dichlorobenzyl)indazole-3-carboxylic acid; 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid; 1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 1-((2,4-dichlorophenyl)methyl)-(9CI)

Indication

Disease Entry	ICD 11	Status	REF
Benign prostatic hyperplasia	GA90	Discontinued in Phase 3	[1]

• Affected Organisms: Humans and other mammals
• ATC Code:
  L01XX07: Lonidamine
  L01XX: Other antineoplastic agents
  L01X: OTHER ANTINEOPLASTIC AGENTS
  L01: ANTINEOPLASTIC AGENTS
  L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C15H10Cl2N2O2
  Canonical SMILES: C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)O
  InChI: InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)
  InChIKey: WDRYRZXSPDWGEB-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 39562
  ChEBI ID: CHEMBL50138
  CAS Number: 50264-69-2
  UNII: U78804BIDR
  DrugBank ID: DB06266
  TTD ID: D09SIR
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References

• [1] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022059)