Details of the Drug

General Information of Drug (ID: DMCU74R)

Drug Name
Daporinad
Synonyms APO-866; FK-866; WK-175
Indication
Disease Entry ICD 11 Status REF
leukaemia 2A60-2B33 Phase 2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 391.5
Logarithm of the Partition Coefficient (xlogp) 3.7
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C24H29N3O2
IUPAC Name
(E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-pyridin-3-ylprop-2-enamide
Canonical SMILES
C1CN(CCC1CCCCNC(=O)/C=C/C2=CN=CC=C2)C(=O)C3=CC=CC=C3
InChI
InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+
InChIKey
KPBNHDGDUADAGP-VAWYXSNFSA-N
Cross-matching ID
PubChem CID
6914657
ChEBI ID
CHEBI:94671
CAS Number
658084-64-1
UNII
V71TF6V9M7
DrugBank ID
DB12731
TTD ID
D0H9SX
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Nicotinamide phosphoribosyltransferase (NAMPT) TTD1WIG NAMPT_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Axin-1 (AXIN1) OTRGZGZ5 AXIN1_HUMAN Gene/Protein Processing [3]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Gene/Protein Processing [3]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Gene/Protein Processing [3]
Nicotinate phosphoribosyltransferase (NAPRT) OTVVN0SL PNCB_HUMAN Gene/Protein Processing [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease leukaemia
ICD Disease Classification 2A60-2B33
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Nicotinamide phosphoribosyltransferase (NAMPT) DTT NAMPT 3.06E-08 -0.63 -0.59
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 -8.8449 -6.7723 -8.8451 66.5052
A-673 GDSC1; GDSC2; CTRP2 -13.0595 -12.2808 -13.0595 93.5646
ES1 GDSC1; GDSC2 -11.4524 -9.515 -11.4524 85.4121
SK-N-MC CTRP2 -10.156 -9.1475 -10.156 74.3684
EW-16 GDSC1 -9.7683 1.1667 -11.0005 75.1317
ES7 GDSC1; GDSC2 -9.7501 -8.1488 -9.7501 73.3386
MHH-ES-1 GDSC1; GDSC2; CTRP2 -9.43 -7.2252 -9.4302 55.6323
TC71 CTRP2 -9.1412 -6.5223 -9.1417 67.4722
ES6 GDSC1; GDSC2 -9.0979 -7.7065 -9.0979 68.4664
ES8 GDSC1; GDSC2 -9.0002 -6.9886 -9.0003 67.6738
ES4 GDSC1 -8.9398 7.8874 -12.6458 65.2761
EW-3 GDSC1; GDSC2 -8.882 -6.16 -8.8839 66.5924
EW-22 GDSC1; GDSC2 -8.7596 -5.2658 -8.7725 65.3001
HOS GDSC1; GDSC2 -8.6755 -7.229 -8.6755 65.2891
TC-71 GDSC1 -8.6049 0.761 -9.6091 73.3592
SJSA-1 GDSC1; GDSC2 -8.5501 -4.4605 -8.5874 63.4325
EW-13 GDSC1 -8.4299 -6.1495 -8.4305 93.4223
EW-7 GDSC1; GDSC2 -8.3622 -6.9261 -8.3622 62.933
MG-63 GDSC1; GDSC2; CTRP2 -8.3009 -6.2066 -8.301 61.987
ES5 GDSC1; GDSC2 -8.0883 -3.9982 -8.136 75.5969
EW-11 GDSC1; GDSC2 -8.0484 -2.1181 -8.309 58.8529
CAL-72 GDSC1; GDSC2 -7.4603 0.2586 -8.2137 54.5262
EW-18 GDSC1 -7.1326 -5.5416 -7.1326 86.7702
U2OS GDSC1; GDSC2 -7.1054 -4.9469 -7.1068 53.4679
EW-24 GDSC1; GDSC2 -6.7394 -5.9143 -6.7394 50.7216
EW-12 GDSC2 -6.6012 -3.4507 -6.6297 65.0716
CHSA0108 GDSC1; GDSC2 -4.687 2.763 -6.0662 48.1442
SK-PN-DW GDSC1; GDSC2 -2.6036 -1.3997 -2.613 19.6306
SW1353 CTRP2 -1.902 0.8377 -3.2996 5.6226
CHSA0011 GDSC1; GDSC2 -0.4072 4.304 -2.5001 16.8068
SaOS-2 GDSC1; GDSC2 -0.4003 10.8629 -5.7685 25.2741
CHSA8926 GDSC1 1.0798 13.0287 -5.6378 28.9753
HuO-3N1 GDSC1 1.2905 8.6682 -3.3113 19.2388
U-CH2 GDSC2 1.7065 3.5788 -0.6463 1.0826
CAL-78 GDSC1 1.7973 3.7181 -0.6602 1.3158
CADO-ES1 GDSC1 1.9774 3.7399 -0.5894 0.8178
Hs 822.T CTRP2 1.9981 3.3256 0.5259 0.7062
NOS-1 [Human HNSCC] GDSC1 2.2307 20.5915 -8.5009 32.4691
NY GDSC1; GDSC2 2.2648 4.4081 -0.7229 0.6871
HuO9 GDSC1 2.2707 5.1063 -1.0011 2.5564
H-EMC-SS GDSC1; GDSC2 2.4135 11.2421 -3.7588 12.6211
EW-1 GDSC1 2.7664 4.7773 -0.6564 0.5436
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 2.9944 5.3726 0.1672 1.061
SK-ES-1 GDSC1; CTRP2 3.1096 4.837 0.4287 0.3464
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 201 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -7.3909 -3.8716 -7.4079 55.8221
JM1 GDSC1; GDSC2; CTRP2 -10.1078 -7.2202 -10.1084 73.6082
GA-10 GDSC1; CTRP2 -13.2443 -11.832 -13.2443 93.8055
697 GDSC1; CTRP2 -13.2404 -11.8666 -13.2404 93.8489
KM-H2 GDSC1; CTRP2 -12.0707 -10.9077 -12.0707 71.2142
ST486 GDSC1; GDSC2; CTRP2 -11.9082 -9.6242 -11.9082 85.1811
M-07e CTRP2 -11.1647 -10.0503 -11.1647 81.0807
ML-2 GDSC1; GDSC2 -11.0968 -9.3532 -11.0968 83.15
Jurkat GDSC1; CTRP2 -11.0206 -7.8972 -11.0219 64.8947
DND-41 GDSC1; GDSC2; CTRP2 -10.9959 -9.7987 -10.9959 79.9533
NOMO-1 GDSC1; GDSC2; CTRP1 -10.9955 -9.1383 -10.9955 82.345
RCH-ACV GDSC1; GDSC2 -10.9952 -8.903 -10.9952 97.211
EM-2 GDSC1; CTRP2 -10.7987 -6.3647 -10.8178 63.2147
SET-2 CTRP2 -10.7222 -9.4145 -10.7222 78.1277
EoL-1 GDSC1; GDSC2; CTRP2 -10.6249 -9.6435 -10.6249 77.4935
NALM-6 GDSC1; GDSC2; CTRP2 -10.5753 -9.0582 -10.5753 62.3919
MY-M12 GDSC2 -10.5051 -7.3289 -10.5071 92.4133
Reh GDSC1; GDSC2 -10.4253 -8.8688 -10.4254 78.37
RPMI-8402 GDSC1; GDSC2; CTRP2 -10.3884 -9.635 -10.3884 61.2897
HAL-01 GDSC1; GDSC2 -10.316 -8.7474 -10.316 77.5567
Peer CTRP2 -10.2424 -9.5609 -10.2424 55.3036
P12-Ichikawa GDSC1; CTRP2 -10.2311 -9.2449 -10.2311 60.3614
KE-37 GDSC1; CTRP2 -10.1391 -8.6315 -10.1391 59.8187
Namalwa GDSC1; GDSC2 -10.1367 -8.9024 -10.1367 76.2753
LC4-1 GDSC1; GDSC2 -10.1189 -8.0565 -10.1189 75.9192
KOPN-8 GDSC1 -10.0961 -8.4102 -10.0961 99.3952
KCL-22 GDSC1; CTRP2 -10.0949 -6.0195 -10.1109 59.3366
TF-1 CTRP2 -10.0782 -8.4779 -10.0782 73.8284
TUR GDSC1 -10.0364 -8.4992 -10.0364 99.5365
GR-ST GDSC1; GDSC2 -10.0344 -7.9264 -10.0344 75.2814
WSU-NHL GDSC1; GDSC2 -10.0338 -8.5932 -10.0338 75.4819
JeKo-1 GDSC1; GDSC2; CTRP2 -10.0314 -8.4635 -10.0314 73.5204
CA46 GDSC1 -10.0224 -7.3523 -10.023 97.3701
EB1 CTRP2 -10.0214 -7.5498 -10.0216 73.2577
RS4;11 GDSC1 -10.0126 -8.032 -10.0126 98.8523
KMOE-2 GDSC1 -9.8879 -7.9356 -9.8879 98.7468
HEL 92.1.7 CTRP2 -9.8832 -8.6122 -9.8832 72.5473
MHH-PREB-1 GDSC1 -9.8793 -8.1765 -9.8793 99.1788
U-937 CTRP1 -9.8528 -7.0218 -9.8584 92.654
SUP-B15 CTRP2 -9.8293 -6.5193 -9.8315 71.5879
VAL GDSC1; GDSC2 -9.7621 -4.8018 -9.8211 70.4581
BV-173 GDSC1 -9.7539 -7.0908 -9.7547 96.8038
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 -9.7309 -7.2483 -9.7311 71.3658
OCI-AML-2 GDSC1; GDSC2 -9.7284 -8.6365 -9.7284 73.2148
U-698-M GDSC1; GDSC2 -9.7168 -8.0429 -9.7168 73.0777
CCRF-CEM GDSC1; GDSC2 -9.71 -7.6925 -9.71 72.9403
ALL-SIL GDSC1 -9.6574 -7.4305 -9.6575 97.7451
P30/OHK GDSC1 -9.6239 -7.8918 -9.6239 98.818
Loucy GDSC1; GDSC2 -9.6209 -8.3414 -9.6209 72.4002
THP-1 GDSC1; GDSC2; CTRP1 -9.523 -6.6515 -9.5248 88.5139
BALL-1 GDSC1 -9.4686 -7.9245 -9.4686 98.9753
DoHH2 GDSC2 -9.4547 -7.9792 -9.4547 92.2933
JVM-2 GDSC1 -9.429 -6.0981 -9.435 93.803
SKM-1 GDSC1; GDSC2; CTRP1 -9.4235 -8.3022 -9.4235 93.0438
PF-382 GDSC1; CTRP2 -9.4117 -8.2169 -9.4117 55.5273
OCI-AML-3 GDSC1; GDSC2; CTRP1 -9.3773 -8.1627 -9.3773 70.5717
MOLT-16 GDSC1 -9.376 -7.794 -9.376 98.7585
RPMI-8866 GDSC1 -9.3681 -7.0033 -9.3685 96.6758
HT GDSC1; GDSC2; CTRP2; CTRP1 -9.3309 -7.6479 -9.3309 65.3824
CML-T1 GDSC1; GDSC2; CTRP2 -9.326 -7.7981 -9.326 55.0216
SUP-T1 GDSC1; GDSC2 -9.2894 -7.6523 -9.2894 69.8873
KO52 CTRP2 -9.2645 2.0589 -10.5081 61.2884
SUP-B8 GDSC1; GDSC2 -9.2641 -5.6298 -9.2763 84.6693
A3/Kawakami GDSC1; CTRP2 -9.2588 -8.1599 -9.2588 68.3877
WIL2 NS GDSC1; GDSC2 -9.2337 -8.2161 -9.2337 69.4939
KE-97 CTRP2; CTRP1 -9.1881 -7.2152 -9.1881 64.7331
Mino CTRP2 -9.149 -7.8556 -9.149 67.655
Mono-Mac-6 GDSC1; GDSC2 -9.098 -6.7222 -9.0985 68.308
MOLM-13 GDSC1; CTRP2 -9.0941 -6.6785 -9.0947 53.6502
KG-1 GDSC1 -9.0796 -5.0754 -9.1044 90.1283
Sc-1 GDSC1 -9.0764 -6.6487 -9.077 95.5807
SU-DHL-5 GDSC1; CTRP1 -9.0524 -8.0676 -9.0524 97.0987
BE-13 GDSC1; GDSC2 -9.0033 -7.9063 -9.0033 67.7599
NU-DUL-1 GDSC1; GDSC2; CTRP1 -8.9869 -7.9764 -8.9869 89.6644
CESS GDSC1 -8.9421 -6.1515 -8.9444 93.8299
ALL-PO GDSC1 -8.9407 -5.3429 -8.9546 90.9459
Karpas-231 GDSC1 -8.9252 -7.2683 -8.9252 97.5763
P32/ISH GDSC1 -8.888 -7.1231 -8.888 97.1291
EB2 GDSC1; GDSC2 -8.88 -6.2636 -8.8814 66.6193
JURL-MK1 GDSC1; CTRP2 -8.8421 -6.9044 -8.8422 52.1662
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 -8.8324 -7.5082 -8.8324 52.1095
P31/FUJ GDSC1; GDSC2; CTRP2 -8.7564 -7.4181 -8.7564 51.6609
DB GDSC1; GDSC2; CTRP2 -8.7422 -6.3966 -8.7425 64.8939
Ramos.2G6.4C10 GDSC1; GDSC2 -8.7402 -7.3358 -8.7402 65.7767
HEL GDSC1; GDSC2; CTRP2 -8.7116 -3.4011 -8.8396 51.3152
MN-60 GDSC1; GDSC2 -8.6624 -7.1735 -8.6624 65.1896
H9 GDSC1 -8.6318 -2.9166 -8.8137 82.3293
IM-9 GDSC1; GDSC2 -8.6148 -7.4757 -8.6148 64.8364
MEG-01 GDSC1; GDSC2 -8.5768 -5.947 -8.5786 64.3829
HC-1 GDSC1 -8.5651 -5.848 -8.5675 92.4327
CTV-1 GDSC1 -8.4993 9.6431 -12.9507 63.0586
OCI-Ly3 CTRP2 -8.394 -6.8857 -8.3941 62.6222
Karpas-1106P GDSC1; GDSC2 -8.3731 -7.1948 -8.3731 63.0169
NCO2 CTRP2 -8.3305 -4.9512 -8.3781 42.6848
CRO-AP2 GDSC1; GDSC2 -8.3246 -2.5014 -8.5444 73.2065
NB4 GDSC1; GDSC2 -8.2551 -5.7457 -8.2567 80.5346
Granta-519 GDSC1; CTRP2 -8.1832 -4.0866 -8.2101 60.7712
SU-DHL-16 GDSC1; GDSC2 -8.1802 -6.6576 -8.1802 81.579
BC-3 GDSC2 -8.1715 -6.3347 -8.1716 81.0739
Raji GDSC1 -8.1184 -5.2298 -8.1239 89.3667
A4/Fukuda GDSC1; GDSC2; CTRP2 -8.0426 -5.2183 -8.0449 60.2057
BL-70 CTRP2; CTRP1 -8.0424 -2.1776 -8.0815 67.4138
KMS-11 GDSC1; GDSC2; CTRP1 -8.0137 -6.0546 -8.014 79.4691
MOLT-4 GDSC1; GDSC2 -7.9974 -6.401 -7.9974 60.1861
OCI-M1 GDSC1; CTRP2 -7.9729 -1.8661 -8.1848 58.5305
SU-DHL-4 GDSC1; GDSC2; CTRP1 -7.9503 -6.4353 -7.9503 79.419
Ku812 GDSC1; GDSC2; CTRP2; CTRP1 -7.8824 -1.9078 -7.9286 58.4739
ATN-1 GDSC1 -7.8603 -3.7092 -7.9184 83.1074
NKM-1 GDSC1; GDSC2 -7.8495 -4.4606 -7.8684 58.8116
Karpas-422 GDSC1; GDSC2; CTRP2 -7.8418 -6.4065 -7.8418 58.9417
HDLM-2 GDSC1; GDSC2; CTRP2 -7.8282 -5.9967 -7.8284 46.1852
CTB-1 GDSC1; GDSC2 -7.7379 -5.5252 -7.7388 76.6047
NK-92MI GDSC2 -7.7238 -6.2968 -7.7238 77.3054
CMK GDSC1; CTRP2 -7.6892 -5.2919 -7.6899 57.9048
F-36P CTRP2 -7.6731 -5.0669 -7.6747 57.7849
LAMA-84 GDSC1; GDSC2; CTRP2 -7.6439 -2.337 -7.8397 45.3879
MOLM-16 GDSC1; GDSC2; CTRP1 -7.594 -5.1122 -7.5967 74.9095
KMS-21-BM CTRP2 -7.5055 -4.6851 -7.5388 37.1713
KHM-1B CTRP2 -7.501 -4.4936 -7.5474 37.1819
BC-1 GDSC1; GDSC2 -7.4582 -5.0301 -7.4608 56.0991
NCI-H929 GDSC1; GDSC2 -7.4058 -6.1206 -7.4058 55.7375
YT GDSC1; GDSC2 -7.3918 -5.8984 -7.3919 55.6314
Kasumi-2 CTRP2 -7.3742 -6.7058 -7.3742 55.8246
JVM-3 GDSC1; GDSC2; CTRP2 -7.2477 -4.668 -7.2526 42.7729
MC116 GDSC1; GDSC2; CTRP2; CTRP1 -7.1876 -5.4223 -7.1876 56.5173
ROS-50 GDSC1; GDSC2 -7.1065 -3.6773 -7.1391 69.152
RPMI-8226 GDSC1; CTRP1 -7.0482 -5.5212 -7.0482 78.3166
K-562 GDSC1; GDSC2; CTRP2 -6.9691 -4.6019 -6.9705 53.1185
MV4-11 GDSC1; CTRP2 -6.9603 -5.9135 -6.9603 41.0644
OPM-2 GDSC1; GDSC2 -6.9564 -3.6386 -6.9863 52.2976
AMO1 GDSC1; GDSC2; CTRP2; CTRP1 -6.9343 -5.5681 -6.9343 45.0567
Daudi GDSC1 -6.8865 -6.1279 -6.8865 85.9133
HuT 78 CTRP2 -6.7762 43.9353 -27.2488 50.2961
Jiyoye GDSC1 -6.7759 -4.3253 -6.781 80.716
OCI-AML-5 GDSC1; CTRP2 -6.7615 -6.0789 -6.7615 51.7402
ARH-77 GDSC1 -6.7193 -4.8053 -6.7201 81.743
RL GDSC1; GDSC2; CTRP2 -6.5792 -4.6173 -6.5795 50.5248
SK-MM-2 GDSC1; GDSC2 -6.554 -4.1538 -6.5594 49.3295
LP-1 GDSC1; GDSC2; CTRP2; CTRP1 -6.4467 -2.0237 -6.5439 49.6588
TALL-1 [Human adult T-ALL] GDSC2 -6.4459 -1.0329 -6.7819 61.1171
MHH-CALL-4 GDSC2; CTRP2 -6.4319 -4.1965 -6.4332 42.2069
JJN-3 GDSC1; CTRP2 -6.4284 -3.8167 -6.433 49.5216
L-540 GDSC1; GDSC2 -6.3851 -3.8333 -6.3946 48.0684
SR GDSC1; GDSC2; CTRP2 -6.3414 -4.7628 -6.3414 41.6897
L-1236 GDSC1; GDSC2 -6.2712 -4.2035 -6.2736 47.2033
L-428 GDSC1; CTRP2 -6.2699 -4.1669 -6.2709 48.4648
OCI-Ly19 GDSC1; GDSC2; CTRP2 -6.1598 -4.1351 -6.1606 47.7307
HD-MY-Z CTRP2 -6.1442 -4.1149 -6.145 47.6271
Ci-1 CTRP2 -5.9393 -3.9388 -5.9402 46.2618
SU-DHL-1 GDSC2; CTRP2 -5.9288 -1.8373 -6.077 35.3953
RPMI-6666 GDSC1; GDSC2; CTRP2 -5.901 -3.2207 -5.9095 46.0218
OCI-Ly10 CTRP2; CTRP1 -5.6649 -2.9994 -5.6749 44.4553
RC-K8 GDSC1 -5.4014 1.125 -6.2363 60.1623
EHEB GDSC1; CTRP2 -5.3428 -2.1163 -5.4181 31.7433
SU-DHL-10 GDSC1 -5.1943 10.8424 -10.186 53.9831
Karpas-45 GDSC1 -5.1508 29.8885 -19.4275 51.794
Karpas-299 GDSC1; GDSC2 -5.1334 -3.1099 -5.1404 38.6602
NU-DHL-1 CTRP2 -5.0853 -1.9315 -5.126 40.6838
SU-DHL-6 GDSC1; GDSC2 -5.0451 -3.031 -5.0526 37.9977
MOLT-13 GDSC1; CTRP2 -4.691 -2.8162 -4.6931 32.3235
SIG-M5 GDSC2; CTRP2 -4.6462 -2.3855 -4.6547 37.6667
BONNA-12 GDSC2 -4.5826 4.0446 -6.4829 47.7495
L-363 GDSC1; GDSC2; CTRP2 -4.3507 -1.9228 -4.368 30.4343
MOLP-8 GDSC1; CTRP2 -4.3272 2.1943 -5.1788 37.8084
DEL GDSC1; CTRP2 -4.2933 -2.8935 -4.2948 25.3341
DG-75 GDSC1 -4.1619 4.3707 -6.1877 50.9589
PL-21 GDSC1; GDSC2 -4.1006 0.8779 -4.7423 42.9489
Hs 611.T CTRP2 -3.9404 1.2714 -4.4681 34.5649
SUP-HD1 GDSC1; CTRP2 -3.7139 -0.776 -3.7904 31.6787
KMS-20 CTRP2 -3.6134 -1.3384 -3.6372 30.8339
MHH-CALL-2 GDSC1 -3.3494 -1.5061 -3.3798 42.0183
PL21 CTRP1 -3.1831 1.3768 -4.7234 28.9158
P3HR-1 CTRP2; CTRP1 -2.975 1.0286 -3.0188 37.1731
QIMR-WIL GDSC1; GDSC2 -2.8532 6.9814 -6.0821 39.3496
Kasumi-1 GDSC1; GDSC2; CTRP2 -2.6816 1.0019 -3.0184 25.7083
Ki-JK CTRP2 -2.2038 -0.6909 -2.798 4.1292
U266B1 GDSC1; GDSC2; CTRP2 -0.7807 3.5705 -1.9598 16.3605
EJM GDSC1; CTRP2; CTRP1 -0.2322 3.6281 -1.4428 12.9265
HL-60 GDSC1; CTRP2 -0.1596 3.8941 -1.499 12.9807
MOLP-2 CTRP2 -0.1342 1.3704 -0.3556 7.1199
Farage GDSC1; GDSC2 0.2145 2.3316 -0.9922 5.6851
SU-DHL-8 GDSC1 0.5231 43.6349 -21.3831 44.2818
VL51 GDSC1; GDSC2 0.8082 16.8265 -7.7496 27.6615
SUP-M2 GDSC1; CTRP2 1.5074 5.3682 -0.777 6.5478
BL-41 GDSC1; GDSC2 1.656 2.9485 -0.4251 0.2576
AML-193 CTRP2 1.7156 6.5078 -1.1826 7.8768
TK [Human B-cell lymphoma] GDSC1 1.7436 3.2018 -0.4836 0.579
Hs 445 GDSC1 1.7477 3.2962 -0.5174 0.7086
KY821 GDSC1 1.7961 3.755 -0.6755 1.3948
MLMA GDSC1; GDSC2 2.0679 4.1478 -0.7079 0.7596
OCI-Ly7 GDSC2 2.1321 3.3945 -0.4052 0.1393
ME1 CTRP2 2.6974 4.412 0.416 0.4768
ME1 GDSC1; GDSC2 2.7468 16.826 -6.2481 20.3943
Mono-Mac-1 CTRP2 2.7708 4.9852 0.218 0.911
GDM-1 GDSC1; CTRP2; CTRP1 2.8463 5.2227 0.1565 1.0237
Karpas-620 GDSC1; GDSC2; CTRP2 2.8974 4.5536 0.4477 0.3322
SUP-T11 CTRP2 3.1056 4.6193 0.5065 0.1799
KMS-18 CTRP2 3.2386 5.3054 0.3054 0.4729
REC-1 CTRP2 3.3358 5.2948 0.3501 0.3558
Toledo CTRP2 3.6696 5.5018 0.4052 0.2218
MHH-CALL-3 CTRP2 4.4243 6.4798 0.3396 0.1349
⏷ Show the Full List of 201 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 -4.851 -2.6489 -4.8568 39.023
PaTu 8988t GDSC1; CTRP2 -7.6463 -2.1894 -7.7945 56.9058
PSN1 GDSC1; GDSC2; CTRP2 -6.9589 -5.9532 -6.9589 53.0564
QGP-1 GDSC1; GDSC2; CTRP2; CTRP1 -6.5717 -4.8952 -6.5717 52.8454
KP-1N GDSC1 -6.4732 5.4561 -9.0488 60.7372
KP-3 GDSC1; GDSC2; CTRP2; CTRP1 -6.3113 -0.615 -6.3751 51.6154
Panc 02.03 GDSC1; GDSC2; CTRP2 -6.011 -1.9791 -6.0897 46.8462
PL4 GDSC1 -5.5901 14.2425 -12.1859 54.3228
KP-4 GDSC1; GDSC2; CTRP2 -5.51 -1.6981 -5.6491 32.9124
YAPC GDSC1; GDSC2; CTRP2 -5.4197 -3.6363 -5.4203 36.4573
Panc 03.27 GDSC1; GDSC2; CTRP2; CTRP1 -5.1393 -1.4607 -5.1468 53.4822
MIA PaCa-2 GDSC2; CTRP2 -4.8983 -2.2162 -4.9176 39.3797
DAN-G GDSC1; CTRP2 -4.8631 4.002 -6.411 42.0791
Panc 04.03 GDSC1; GDSC2; CTRP2 -4.8167 -0.1321 -5.0786 39.4855
BxPC-3 GDSC1; GDSC2; CTRP2 -4.5792 -0.8527 -4.7931 27.6603
PK-59 CTRP2 -4.3691 -2.449 -4.3728 30.5002
PaTu 8988s CTRP2 -4.3099 -0.1739 -4.5218 36.0508
CFPAC-1 GDSC1; CTRP2 -4.2554 -1.0827 -4.3996 25.5408
PaTu 8902 GDSC1; CTRP1 -4.154 0.6355 -4.2167 68.1515
AsPC-1 GDSC1; CTRP2 -3.9637 -0.8546 -4.0461 33.3604
HPAC GDSC1; CTRP2 -3.7193 -0.612 -3.8164 27.0789
KP-2 GDSC1; CTRP2 -3.4841 0.2898 -3.7196 30.6788
MZ-PC-1 GDSC1; GDSC2 -3.4785 2.2058 -4.564 38.8871
SUIT-2 GDSC1; CTRP2; CTRP1 -2.9104 2.1841 -3.0549 36.5186
TCC-Pan2 CTRP2 -2.4573 1.1481 -2.8145 20.7005
PK-45H CTRP2 -2.3628 2.2238 -3.0643 24.8983
SW1990 GDSC1; GDSC2; CTRP2 -2.3347 1.4699 -2.7777 23.7872
Hs 766T GDSC1; GDSC2; CTRP2 -2.2698 1.529 -2.7257 23.404
SNU-213 CTRP2 -2.1057 1.225 -3.6648 7.5567
Capan-1 GDSC2; CTRP2 -2.0551 2.9097 -2.9973 23.7559
Panc 08.13 GDSC1; CTRP2 -1.8721 1.0008 -2.1346 20.0643
SU.86.86 GDSC1; CTRP2 -1.5209 2.6233 -2.3175 16.8108
HuP-T3 GDSC1; CTRP2 -1.4139 5.2606 -3.3692 23.3214
HPAF-II GDSC1; GDSC2; CTRP2 0.0627 3.6795 -1.7878 6.5481
HuP-T4 CTRP2; CTRP1 0.5816 1.7933 0.5813 20.6632
Panc 10.05 GDSC1; GDSC2 0.8564 11.8656 -5.2351 20.8758
SNU-410 CTRP2 4.2457 5.9883 0.4437 0.0746
Capan-2 GDSC1; GDSC2; CTRP2; CTRP1 6.9468 8.9419 4.3744 0.5612
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 74 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 -5.1295 -0.6882 -5.3156 41.3294
CHL-1 GDSC1; GDSC2 -7.4391 -5.894 -7.4391 55.9869
A-375 GDSC1; GDSC2; CTRP2; CTRP1 -7.165 -5.3816 -7.1652 42.2726
MeWo GDSC1; GDSC2; CTRP2 -6.4728 -3.9995 -6.4757 49.8162
RPMI-7951 CTRP2 -6.2023 -5.3903 -6.2023 28.3805
IST-MEL1 GDSC1; GDSC2 -6.0878 0.7801 -6.8722 46.7134
Mel JuSo GDSC1; CTRP2 -5.8577 -4.0136 -5.8582 38.9444
HMCB CTRP2 -5.4845 -4.7605 -5.4845 43.2274
HMV-II GDSC1; GDSC2 -5.4427 1.8857 -6.5438 43.1641
COLO 800 GDSC1; GDSC2; CTRP2 -5.3437 -2.4785 -5.3636 42.3443
IGR-1 CTRP2 -5.244 -3.5073 -5.2446 41.6264
MMAc-SF GDSC1; GDSC2 -4.745 -1.7671 -4.8244 47.7345
WM278 GDSC1 -4.7288 8.2731 -8.5252 52.9635
WM266-4 CTRP2 -4.7008 -4.0259 -4.7008 38.0034
IGR-37 GDSC1; GDSC2; CTRP2 -4.6713 -2.9371 -4.6725 37.8107
IPC-298 GDSC1; GDSC2; CTRP2 -4.5633 -2.4756 -4.5687 31.6078
SH-4 GDSC1; GDSC2 -4.5289 0.3297 -5.0363 35.79
Mel Ho GDSC1; GDSC2; CTRP2 -4.4826 1.0625 -5.2184 28.6685
IGR-39 CTRP2 -4.4287 1.0359 -4.9344 37.6109
G-361 GDSC1; CTRP2; CTRP1 -4.2798 -2.1286 -4.2799 43.0982
A2058 CTRP2 -4.2078 -3.5936 -4.2078 34.7168
M14 GDSC1 -4.0937 7.7638 -7.6607 50.4151
SK-MEL-30 GDSC1; GDSC2; CTRP2 -3.9828 -1.8035 -3.9958 28.333
SK-MEL-2 GDSC1; GDSC2; CTRP2 -3.66 -0.2532 -3.8064 31.5512
Hs 852.T CTRP2; CTRP1 -3.6579 -0.3426 -3.6672 40.2482
CJM [Human melanoma] CTRP2 -3.628 -2.8899 -3.628 30.8519
WM1799 CTRP2 -3.5842 -2.2264 -3.585 26.0346
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 -2.968 -1.4886 -2.9717 22.5435
WM793 GDSC1; CTRP2 -2.5573 -1.1149 -2.5631 20.2175
Hs 294T CTRP2 -2.4593 0.2187 -2.5942 23.522
RVH-421 GDSC1; GDSC2; CTRP2 -2.2368 1.4838 -2.6754 23.123
COLO 829 GDSC1; CTRP2 -2.1258 2.3154 -2.8431 23.4017
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 -1.9117 0.9593 -2.1666 17.2936
SK-MEL-24 GDSC1; GDSC2; CTRP2 -1.8624 1.655 -2.3244 20.7268
LOX-IMVI GDSC1; GDSC2; CTRP2 -1.8175 2.241 -2.4847 21.1893
COLO 792 GDSC1; CTRP2 -1.8017 1.3099 -2.1476 19.8984
MZ-MEL-7 GDSC1; GDSC2 -0.9913 2.6817 -2.2358 17.2509
COLO 679 GDSC1; GDSC2 -0.657 9.4383 -5.2773 24.3843
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 -0.5422 0.298 -0.6933 3.6885
Hs 944.T CTRP2; CTRP1 -0.4209 0.2786 -0.4209 25.2893
GAK GDSC1; GDSC2 -0.3588 8.8627 -4.7338 21.8545
CP66-MEL GDSC1; GDSC2 -0.1017 6.5779 -3.374 20.4932
COLO 741 CTRP2 -0.0859 6.0081 -4.4978 7.5969
COLO 783 GDSC1; GDSC2 -0.0324 4.2461 -2.1501 13.5894
LB2518-MEL GDSC1; GDSC2 0.0389 4.5311 -2.2332 13.8737
WM115 GDSC1; GDSC2; CTRP2 0.0578 3.0916 -0.9067 10.0456
LB373-MEL-D GDSC1; GDSC2 0.119 6.4289 -3.1158 18.5366
A101D GDSC1; CTRP2 0.2075 2.4879 -0.476 7.9296
UACC-257 GDSC1; CTRP2 0.2641 4.4267 -1.3595 11.4364
MZ-MEL-2 GDSC1; GDSC2 0.3204 2.9288 -1.2067 6.7558
UACC-62 GDSC1; GDSC2; CTRP2 0.3995 4.0584 -1.0545 9.8736
451Lu GDSC1; GDSC2 0.4836 3.2038 -1.2189 6.4179
G-mel GDSC1; GDSC2 0.5952 2.9912 -1.0333 5.0007
A-431 GDSC1; GDSC2 0.6823 11.7752 -5.3291 26.006
Hs 938.T GDSC1; GDSC2 0.9029 5.3559 -1.9678 9.9721
A-388 GDSC1; GDSC2 1.4029 7.3623 -2.5876 12.3184
CP50-MEL-B GDSC1; GDSC2 1.4277 9.6934 -3.7144 17.8949
Hs 936.T CTRP2; CTRP1 1.7671 2.2725 1.7671 15.1915
K029AX CTRP2 1.9052 6.4743 -1.0243 6.9109
DJM-1 GDSC2 1.9069 6.6028 -1.8797 7.2824
VMRC-MELG GDSC1; GDSC2 2.2633 4.1305 -0.6181 0.5746
WM35 GDSC1 2.3087 5.0677 -0.9665 2.3124
Hs 895.T CTRP2 2.3732 3.9665 0.4448 0.6777
WM1552C GDSC1; GDSC2 2.3868 4.2724 -0.621 0.3882
Hs 839.T CTRP2 2.4291 3.5831 0.619 0.2231
Hs 934.T CTRP2 2.7821 3.9356 0.6274 0.1155
WT2-iPS GDSC1; GDSC2; CTRP2 2.9147 4.6263 0.4274 0.4266
SK-MEL-3 GDSC1; GDSC2; CTRP2 2.9533 4.8575 0.355 0.5768
SK-MEL-31 GDSC1; GDSC2; CTRP2 2.9748 4.6249 0.4529 0.2969
WM88 CTRP2 3.4956 5.2908 0.4146 0.2509
HT-144 GDSC1; CTRP2 3.7807 5.258 0.5286 0.0711
WM983B CTRP2 3.8589 5.8098 0.367 0.2319
Hs 940.T GDSC1; GDSC2; CTRP2 4.1406 15.2337 -3.6999 13.5495
EquiPSC Line K2 GDSC1; GDSC2 1.848 16.3124 -6.6719 27.0085
⏷ Show the Full List of 74 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC1; GDSC2 -8.6235 -6.6829 -8.6236 64.8683
FLO-1 GDSC1; GDSC2 -8.4824 -6.4516 -8.4826 63.8024
ESO-51 GDSC1 -8.0186 -4.2704 -8.0493 85.5284
OACP4 C GDSC1 -6.8129 0.3357 -7.5295 68.4431
KYAE-1 GDSC1; GDSC2 -6.8013 -4.0917 -6.8112 51.1768
OACM5.1 C GDSC1 -5.8254 -2.5531 -5.8838 69.2992
SK-GT-4 GDSC1; GDSC2 -3.1019 9.753 -7.6533 36.6082
ESO-26 GDSC1 -0.4509 16.5983 -8.6778 38.991
HCE-4 GDSC1; GDSC2 0.5065 2.6942 -0.9519 4.7039
KYSE-50 GDSC1 2.0152 4.0589 -0.6965 1.2606
TE-12 GDSC1; GDSC2 3.42 12.382 -3.6255 13.1983
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 -8.0725 -5.6812 -8.073 60.4503
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 -12.6937 -12.1354 -12.6937 91.2765
SK-N-DZ GDSC1; CTRP2 -12.6823 -10.4828 -12.6823 89.6264
SJNB-14 GDSC1; GDSC2 -12.3579 -11.0755 -12.3579 92.1942
Kelly GDSC1; GDSC2 -11.9312 -9.7689 -11.9312 88.131
SiMa GDSC1; CTRP2 -10.9536 -8.827 -10.9536 64.6125
SJNB-10 GDSC1; GDSC2 -10.4993 -9.2833 -10.4993 78.9926
GI-ME-N GDSC1 -10.0689 -0.248 -10.9217 78.3048
IMR-5 GDSC1 -9.7939 -7.9512 -9.7939 98.8328
SK-N-BE(2)-M17 GDSC1 -9.3296 -3.5305 -9.4793 85.3549
GOTO GDSC1 -9.1896 -6.8233 -9.1901 96.1499
SJNB-13 GDSC1 -9.0944 -6.7945 -9.0947 96.0611
KP-N-YS GDSC2 -8.9141 -6.2042 -8.9159 85.0665
KP-N-RT-BM-1 GDSC2 -8.2291 -5.4995 -8.2324 79.8421
CHP-212 GDSC1; CTRP2 -8.1636 -6.7595 -8.1636 61.0871
MHH-NB-11 GDSC2; CTRP2 -8.1326 -3.6024 -8.2109 48.046
SK-N-MC-IXC GDSC1; GDSC2 -8.1265 -6.0894 -8.1268 80.3518
CHP-126 GDSC1; GDSC2 -7.637 -4.7513 -7.6448 74.6092
NB69 GDSC2 -7.5899 -6.2327 -7.5912 42.8354
NB1 GDSC1; CTRP2 -7.515 -6.5729 -7.515 48.354
SJNB-5 GDSC1; GDSC2 -7.4797 -5.8326 -7.4798 74.7916
SK-N-SH GDSC1; GDSC2; CTRP2 -7.4358 -5.8481 -7.4358 56.2351
SJNB-17 GDSC2 -7.3006 -5.6823 -7.3006 73.0665
NB(TU)1 GDSC1 -7.1957 -4.946 -7.1976 85.1507
SK-N-FI GDSC1; GDSC2; CTRP2 -7.1935 -6.0288 -7.1935 54.6201
NH-6 CTRP2 -6.4291 -4.5531 -6.4294 49.5247
SJNB-7 GDSC1; GDSC2 -6.0389 1.2169 -6.9588 46.5273
LA-N-6 GDSC1; GDSC2 -4.2514 1.8598 -5.2534 44.7746
SK-N-AS GDSC1; GDSC2; CTRP2 -4.0476 2.0967 -4.8429 35.9644
SJNB-12 GDSC1; GDSC2 -3.0609 6.7555 -6.1756 33.5138
KP-N-YN GDSC1; CTRP2 -2.3985 9.4228 -6.2956 34.0201
SJNB-6 GDSC1; GDSC2 0.9902 11.875 -5.1338 24.5701
TGW GDSC1; GDSC2 2.0383 3.7696 -0.5753 0.4303
NH-12 GDSC1 2.3371 3.9974 -0.5407 0.4191
SK-N-BE(2) CTRP2 3.9311 6.1933 0.2569 0.3871
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -7.4792 -4.1225 -7.5586 37.137
SNU-478 CTRP2 -5.8261 -4.7635 -5.8264 25.8747
SNU-1196 CTRP2 -5.7297 -3.0759 -5.8304 25.5732
HuH-28 CTRP2 -5.1446 -2.6496 -5.2726 21.7705
HuCC-T1 GDSC1; GDSC2; CTRP2 -4.0995 -1.4222 -4.181 24.4307
SNU-869 CTRP2 -4.0857 -2.454 -4.0873 33.9079
SNU-308 CTRP2 -2.3959 2.5665 -4.5857 11.991
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 87 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 GDSC1; CTRP2 -10.9504 -9.4378 -10.9504 79.6105
HMC-1-8 CTRP2 -8.9645 -6.0547 -8.9776 46.8102
MFM-223 GDSC1; GDSC2 -8.0442 -5.8336 -8.0449 60.5034
HCC1599 GDSC2 -7.2586 -3.6055 -7.3003 70.0599
HCC2157 GDSC1 -6.3352 5.0281 -8.7254 60.602
JIMT-1 GDSC1; CTRP2 -6.2665 -3.5874 -6.2807 37.012
HCC1143 GDSC1 -6.2505 16.6587 -13.9773 55.3111
HCC1806 GDSC1; CTRP2 -6.1494 -3.6352 -6.16 36.3111
CAL-51 GDSC1; CTRP2 -6.0974 -3.8465 -6.0994 39.5458
HCC1569 GDSC1; GDSC2 -6.009 0.943 -6.8377 56.7335
T-47D GDSC1; CTRP2 -5.9294 -2.9145 -5.9469 46.2265
MDA-MB-468 GDSC1; GDSC2; CTRP2 -5.8306 -4.0993 -5.8308 45.5354
Hs 578T GDSC1; GDSC2; CTRP2 -5.7639 -0.7577 -5.9867 45.4477
MRK-nu-1 GDSC1; GDSC2 -5.7366 -3.4112 -5.746 43.2038
CAL-120 GDSC1; CTRP2 -5.1534 -1.5802 -5.2847 30.7923
MDA-MB-453 GDSC1; GDSC2 -4.0524 12.3575 -9.8125 41.9236
CAL-148 GDSC2; CTRP2 -3.0863 -0.8897 -3.5794 9.4597
OCUB-M GDSC1; GDSC2 -3.0678 6.3281 -5.9804 33.058
YMB-1-E GDSC2 -2.8583 5.8483 -5.5495 38.3163
ZR-75-1 CTRP2 -2.6078 2.0047 -3.2511 22.4385
CAL-85-1 GDSC1; GDSC2; CTRP2 -2.2969 2.7155 -3.1779 25.107
HCC70 GDSC1; GDSC2 -2.0123 7.5474 -5.5586 28.7719
MDA-MB-231 GDSC1; GDSC2; CTRP2 -1.8068 2.4432 -2.5501 18.2459
HCC38 GDSC1; GDSC2; CTRP2 -1.368 4.1235 -2.8027 21.1387
COLO 824 GDSC1 -1.3287 4.6904 -3.5273 30.1618
EFM-192A GDSC1; CTRP2 -0.6698 13.44 -6.6611 30.5406
KPL-1 CTRP2 -0.6609 15.7073 -9.724 25.0363
HCC1954 GDSC1; CTRP2 -0.5601 6.3986 -3.6773 14.5715
HCC1187 GDSC1 -0.5119 17.0127 -8.9366 39.4477
UACC-812 GDSC2 -0.4642 4.458 -5.1675 5.4629
MCF-7 GDSC1; CTRP2; CTRP1 -0.3349 16.985 -8.7732 27.9009
BT-474 GDSC1; CTRP2 -0.2926 5.0729 -2.1934 16.0961
CAMA-1 GDSC1; GDSC2; CTRP2 -0.1337 10.5226 -5.3731 19.3513
HCC1395 GDSC1; GDSC2; CTRP2 0.2206 2.8066 -1.224 4.1927
HCC1937 GDSC1; CTRP2 0.689 7.7572 -3.3204 11.1527
MDA-MB-436 GDSC1; GDSC2 0.7346 6.4748 -2.6474 10.9664
HCC202 GDSC1; CTRP2 0.7613 5.7991 -1.6012 11.386
EFM-19 GDSC1; GDSC2 0.7891 14.5149 -6.6107 25.016
HDQ-P1 GDSC1 1.0077 7.5859 -2.9894 18.3663
Evsa-T GDSC1 1.2374 7.1906 -2.6235 15.5156
HCC1419 GDSC1; CTRP2 1.4038 5.6749 -1.01 7.7011
Hs 578Bst CTRP2 1.9105 3.7632 0.2833 1.6437
BT-483 GDSC1; GDSC2 1.9813 11.0803 -3.9882 14.2597
ZR-75-30 GDSC1; GDSC2; CTRP2 2.0071 5.55 -0.5002 4.6093
MDA-MB-175-VII GDSC1; GDSC2 2.1263 14.1497 -5.3904 18.9254
HCC1500 GDSC1; CTRP2 2.1389 6.4376 -0.8381 5.7853
HCC2218 GDSC1; GDSC2; CTRP2 2.3522 7.0696 -0.9951 6.1046
BT-20 GDSC1; CTRP2 2.4186 8.5542 -1.67 8.7168
MDA-MB-330 GDSC1; GDSC2 2.5229 5.3333 -0.9726 1.6709
HCC1428 GDSC1; CTRP2 2.5836 9.3743 -1.952 9.5753
MDA-MB-415 GDSC1; GDSC2 2.8299 17.8033 -6.6674 21.3936
UACC-893 GDSC1; GDSC2 2.8371 15.2684 -5.4183 21.2646
MDA-MB-361 GDSC1; CTRP2 3.122 5.0287 0.3617 0.481
BT-549 GDSC1; GDSC2; CTRP2 3.3434 4.9979 0.4615 0.2186
MDA-MB-157 GDSC1; GDSC2; CTRP2 3.4926 15.7277 -4.4039 16.7737
SK-BR-3 CTRP2 3.6574 5.48 0.4083 0.2202
BT 179 CTRP2 -8.8186 -6.9398 -8.8187 65.4408
BT 286 CTRP2 -8.7129 -5.759 -8.7148 64.5818
BT 428 CTRP2 -7.5366 -6.4451 -7.5366 56.9072
BT 228 CTRP2 -7.4691 -7.0246 -7.4691 56.4578
BT 271 CTRP2 -7.4198 -5.9136 -7.4198 56.1284
BT 416 CTRP2 -7.4124 -6.6278 -7.4124 56.0792
BT 245 CTRP2 -7.2 -6.0743 -7.2 54.6634
BT 232 CTRP2 -7.1674 -6.145 -7.1674 54.4464
BT 172 CTRP2 -7.1473 -5.9392 -7.1473 54.3124
BT147 CTRP2 -7.134 -5.8743 -7.134 54.2234
BT 504 CTRP2 -7.0467 -5.1251 -7.0469 53.6405
BT 330 CTRP2 -6.1598 -4.2308 -6.1603 47.7301
BT 444 CTRP2 -5.9917 -0.075 -6.3658 47.0047
BT 216 CTRP2 -5.7683 -0.1491 -6.1073 45.6184
BT 440 CTRP2 -5.7056 -0.9012 -5.9004 45.0406
BT 482 CTRP2 -5.3968 -1.0979 -5.5402 42.9704
BT 131 CTRP2 -5.2362 -1.5846 -5.3124 41.7728
BT 328 CTRP2 -5.2244 -1.0151 -5.3676 41.8498
BT 422 CTRP2 -5.1501 -0.2131 -5.4237 41.6493
BT 159 CTRP2 -4.548 -0.2519 -4.7646 37.6232
BT 333 CTRP2 -3.6385 0.5228 -3.9403 31.9147
BT 498 CTRP2 -2.8743 6.3968 -5.3509 33.3316
BT 248 CTRP2 -2.1603 3.1627 -3.2104 24.8227
BT 224 CTRP2 -1.8302 4.3809 -3.3876 24.5115
BT 231 CTRP2 -1.3899 6.8957 -4.1173 25.7602
BT 112 CTRP2 -1.0734 3.9493 -2.4264 18.9363
BT 340 CTRP2 -0.3107 7.4426 -3.3697 20.5964
BT 320 CTRP2 2.2313 8.2307 -1.6475 8.9235
BT 239 CTRP2 2.9155 5.7107 -0.0156 1.6993
BT 139 CTRP2 3.2542 7.3397 -0.5467 3.2271
BT 359 CTRP2 3.6178 12.9689 -2.9681 11.8124
⏷ Show the Full List of 87 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -1.9475 1.7085 -3.7728 7.698
Cancer Drug Sensitivity Data Curated from 65 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med GDSC1; GDSC2; CTRP2 -11.4114 -10.2943 -11.4114 82.7175
SF539 GDSC1; GDSC2; CTRP2 -9.081 -7.7869 -9.081 67.2022
D-263MG GDSC1; GDSC2 -8.7777 -6.8975 -8.7777 66.0294
42-MG-BA GDSC1; CTRP2 -8.6787 -7.1266 -8.6787 64.5188
H4 GDSC1; GDSC2 -7.8959 -5.0403 -7.9018 59.2949
U-118MG GDSC1; CTRP2 -7.8808 -1.8479 -8.0889 58.0378
A-172 GDSC1; CTRP2 -7.8251 -5.393 -7.8258 58.8053
SF268 GDSC1; CTRP2 -7.4615 -5.8563 -7.4615 56.4062
D-423MG GDSC1; GDSC2 -7.4154 -3.3078 -7.4849 70.495
MOG-G-UVW GDSC1; GDSC2 -7.2132 -5.7391 -7.2132 54.2874
GI-1 GDSC1; GDSC2 -7.1376 -2.0608 -7.3391 53.3195
AM-38 GDSC1 -7.0441 -4.3969 -7.051 82.4752
ONS-76 GDSC1; GDSC2; CTRP2 -6.9582 -4.8987 -6.9594 41.0554
GB-1 GDSC1; CTRP2 -6.9378 -5.9249 -6.9378 40.9316
SF126 GDSC1; GDSC2; CTRP2 -6.7345 -5.8982 -6.7345 39.7324
KNS-60 CTRP2 -6.7085 -5.7699 -6.7085 43.7744
LNZTA3WT4 GDSC1; GDSC2 -6.4152 -3.1882 -6.4519 48.3187
M059J GDSC1; GDSC2 -6.37 -4.6315 -6.3705 47.9428
LN-229 GDSC1; CTRP2; CTRP1 -6.3652 -4.0256 -6.3706 37.5691
SF295 GDSC1; GDSC2; CTRP2; CTRP1 -6.239 -4.9604 -6.239 51.3341
T98G GDSC1; GDSC2; CTRP2 -6.1301 -2.2248 -6.1933 47.6036
D-566MG GDSC1; GDSC2 -6.093 -3.7116 -6.1008 60.8815
U-251MG GDSC1; CTRP2 -4.9742 -2.6882 -4.9808 39.8468
8-MG-BA GDSC1; CTRP2 -4.9463 -4.1012 -4.9463 39.6397
KNS-42 GDSC1; GDSC2; CTRP2 -4.925 -2.2032 -4.9456 39.5613
Onda 10 GDSC1; GDSC2 -4.7645 0.6649 -5.3953 48.3265
CCF-STTG1 CTRP2 -4.6504 -3.557 -4.6504 37.6672
NMC-G1 GDSC1; GDSC2; CTRP2 -4.4434 -0.7419 -4.6687 26.896
GMS-10 CTRP2 -4.4027 -2.5204 -4.4059 36.0266
Becker GDSC1; GDSC2; CTRP2 -4.3443 -3.1911 -4.3443 35.6269
LN-18 GDSC1; CTRP2 -4.3238 0.7584 -4.9456 27.4087
TM-31 CTRP2 -4.3091 -3.7846 -4.3091 35.3917
Daoy GDSC1; CTRP2 -4.2879 -2.0992 -4.3144 25.3765
SNU-1105 CTRP2 -4.2551 -1.4948 -4.6015 16.6378
YKG-1 GDSC1; GDSC2; CTRP2 -4.1848 -3.5774 -4.1848 34.5637
GaMG GDSC1; GDSC2; CTRP2; CTRP1 -3.9688 -1.817 -3.969 41.6631
SNU-201 CTRP2 -3.8195 0.3102 -4.8575 16.4205
KALS-1 GDSC1; GDSC2; CTRP2 -3.4946 -0.6773 -3.5694 25.7386
SNU-466 CTRP2 -3.2493 -0.2469 -4.0288 11.6645
SNB-75 GDSC1; GDSC2; CTRP2 -2.9053 2.2385 -3.6545 28.5944
SW1088 GDSC1; GDSC2; CTRP2 -2.5949 -0.2319 -2.6684 20.6266
GOS-3 CTRP2 -1.9935 1.9692 -2.5748 22.0329
KG-1-C CTRP2 -1.3091 1.6394 -1.7196 16.8649
M059K CTRP2 -1.0016 2.8239 -1.856 16.5304
LN-405 GDSC1 -0.8647 26.8242 -14.1393 43.8625
DK-MG GDSC1; CTRP2 -0.7845 3.3743 -1.8749 16.0351
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -0.7841 9.2026 -5.2701 24.6707
SK-MG-1 GDSC1 -0.4998 13.3763 -7.1091 36.8922
YH-13 GDSC1; GDSC2; CTRP2 -0.3183 3.0867 -1.2752 12.4608
KNS-81-FD GDSC1; GDSC2 -0.1171 6.198 -3.1971 19.6628
Hs 683 GDSC1; GDSC2; CTRP2 0.5583 3.4895 -0.6296 7.7575
Onda 11 GDSC1; GDSC2 0.5592 9.9143 -4.4992 23.4385
U-87MG ATCC GDSC1; CTRP2 0.6758 4.2123 -1.573 4.7963
CAS-1 GDSC1; CTRP2 0.7212 22.1286 -10.4692 29.0728
D-542MG GDSC1; GDSC2 1.0197 8.3342 -3.3508 17.2194
D-247MG GDSC1; GDSC2 1.1745 5.2237 -1.7096 7.805
D-336MG GDSC1; GDSC2 1.2726 6.7364 -2.3755 11.4491
D-502MG GDSC1; GDSC2 1.2786 5.9067 -1.9676 9.0937
SW1783 GDSC1; GDSC2; CTRP2 1.609 8.6749 -2.3425 12.7592
D-245MG GDSC2 1.6278 7.7073 -2.5958 11.8452
D-392MG GDSC1; GDSC2 1.95 5.7019 -1.4364 3.5583
KINGS-1 GDSC1; GDSC2 2.2156 13.9996 -5.2501 18.3136
DBTRG-05MG GDSC1; CTRP2 2.2266 5.0053 -0.0961 2.3084
KNS-81 CTRP2 2.2546 3.2359 0.6772 0.1484
MOG-G-CCM GDSC1; GDSC2 3.3555 15.6713 -5.2459 16.3633
⏷ Show the Full List of 65 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 -5.444 8.9071 -9.529 55.3408
TGBC1TKB GDSC1; GDSC2 0.8213 8.6575 -3.6648 15.1833
TGBC24TKB GDSC1 0.927 3.6691 -1.1314 6.0592
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC1; CTRP2 -8.6338 -7.1924 -8.6338 50.9379
MFE-280 GDSC1; GDSC2 -8.6104 -6.8966 -8.6104 64.7887
JHUEM-2 CTRP2; CTRP1 -8.5798 -6.3071 -8.5832 44.2331
EN GDSC1; GDSC2; CTRP2 -7.7475 -4.8399 -7.751 58.2473
AN3-CA GDSC1; CTRP2 -6.9714 -4.2091 -6.9758 53.123
MFE-319 GDSC1; CTRP2; CTRP1 -6.9649 -3.4199 -6.9667 62.9821
JHUEM-1 CTRP2 -6.5134 -2.5428 -6.5691 50.084
HEC-59 CTRP2; CTRP1 -5.9591 -2.962 -5.96 50.0622
HEC-50B CTRP2 -5.4302 -2.9334 -5.4381 36.5371
ESS-1 GDSC1; GDSC2; CTRP2 -5.0564 -3.0742 -5.0586 40.3808
HEC-108 CTRP2; CTRP1 -4.6662 -2.3008 -4.6665 44.1883
HEC-1-B CTRP2 -4.5812 -0.6761 -5.2458 19.9869
JHUEM-7 CTRP2 -4.2299 -2.7555 -4.2305 34.8661
HEC-265 CTRP1 -3.7449 -2.0533 -3.7449 98.991
JHUEM-3 CTRP2 -3.7329 -1.5119 -3.7515 31.613
HEC-6 CTRP2; CTRP1 -2.5017 -2.0151 -2.5017 34.3528
KLE GDSC1; CTRP2; CTRP1 -1.6298 -0.1832 -1.6299 30.3915
HEC-151 CTRP2; CTRP1 -0.782 2.8188 -1.6265 12.8224
HEC-251 CTRP2; CTRP1 2.3825 8.3373 0.8736 16.0498
MFE-296 GDSC1; CTRP2 2.7737 5.1262 0.1603 1.2464
HEC-1-A CTRP2 3.4336 5.0405 0.4801 0.1719
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 -5.4416 -4.6296 -5.4416 47.711
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SN12C GDSC1; GDSC2 -8.0175 -3.5781 -8.0925 59.5448
KTCTL-195 GDSC1; GDSC2 -7.2649 -4.1697 -7.281 54.5912
UO-31 GDSC1; GDSC2; CTRP2 -6.8877 -5.1268 -6.8878 52.5813
NCC010 GDSC1; GDSC2 -5.9343 -1.5469 -6.129 58.0526
SW13 GDSC1; GDSC2 -5.9288 5.3917 -8.4549 46.9478
LB2241-RCC GDSC1; GDSC2 -5.925 3.7577 -7.774 54.8279
BFTC-909 GDSC1; CTRP2 -5.6421 -2.4063 -5.7047 33.4698
786-O GDSC1; CTRP2 -5.5967 -3.3365 -5.6001 43.9848
769-P GDSC1; GDSC2; CTRP2 -5.3403 -1.6474 -5.4749 31.9018
Caki-1 GDSC1; GDSC2; CTRP2 -3.951 -1.8517 -3.9617 33.0405
TK-10 GDSC1; GDSC2 -3.7626 2.6875 -5.0588 32.8849
KMRC-3 CTRP2 -2.9618 2.5591 -3.831 29.3514
ACHN GDSC1; GDSC2; CTRP2 -2.5252 0.7302 -2.777 24.3705
SW156 GDSC1; GDSC2 -2.4521 3.7306 -4.1628 32.5849
KMRC-20 GDSC1; CTRP2 -1.8355 2.1603 -2.8312 14.1606
KMRC-2 CTRP2 -1.588 2.2403 -2.2388 19.6135
CAL-54 GDSC1; GDSC2; CTRP2 -1.3672 3.6594 -2.5954 20.3565
RCC10RGB CTRP2; CTRP1 -0.7242 8.1237 -4.0841 23.9892
VMRC-RCZ GDSC1; GDSC2; CTRP2 -0.3223 5.3648 -2.3629 16.8366
A-704 GDSC1 -0.2281 19.6027 -9.9921 39.86
VMRC-RCW GDSC2; CTRP2; CTRP1 -0.0341 0.9779 -0.0341 23.5039
RXF 393L GDSC1; GDSC2 0.1628 5.5512 -2.6412 15.8625
KMRC-1 GDSC1; GDSC2; CTRP2 0.2984 9.1159 -3.6565 20.2359
OS-RC-2 GDSC1; CTRP2 0.3839 6.3108 -2.8415 9.9132
NCC021 GDSC1; GDSC2 0.4249 7.5724 -3.4382 19.2524
BB65-RCC GDSC1; GDSC2 0.4296 17.5404 -8.4148 33.7823
HA7-RCC GDSC1; GDSC2 0.4396 11.9074 -5.5914 27.4561
SNU-1272 CTRP2 0.7806 2.2886 -2.4256 0.0856
LB1047-RCC GDSC1; GDSC2 0.8778 4.5406 -1.5868 7.739
KTCTL-140 GDSC1; GDSC2 1.2615 16.3782 -7.163 29.4824
LB996-RCC GDSC1 1.3254 9.1256 -3.5108 20.146
KTCTL-13 GDSC1; GDSC2 1.3289 4.3499 -1.1924 4.4441
A-498 GDSC1 1.5439 10.3116 -3.9325 21.4863
TUHR10TKB CTRP2 1.8142 4.0238 0.1009 2.1024
KTCTL-1M GDSC1; GDSC2 1.9175 10.6767 -3.8369 17.2731
KTCTL-26A GDSC1; GDSC2 2.0533 6.6116 -1.7916 6.516
KTCTL-21 GDSC1; GDSC2 3.127 13.9055 -4.5507 17.5909
Caki-2 CTRP2 3.4209 4.7161 0.5866 0.0642
TUHR14TKB CTRP2 3.9479 6.1558 0.2771 0.3472
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 61 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 320HSR GDSC1; GDSC2 -9.96 -8.2309 -9.96 74.8749
NCI-H716 GDSC1; CTRP2 -9.0052 -6.3029 -9.0059 66.5603
HCT 8 CTRP2; CTRP1 -7.9029 -5.4418 -7.9037 59.3199
SW48 GDSC1; CTRP2 -7.8556 -1.056 -8.3095 46.7926
LoVo GDSC1; GDSC2; CTRP1 -7.6253 -4.6423 -7.6352 57.2701
COLO 320 CTRP2; CTRP1 -7.5535 -2.7683 -7.6376 56.5699
LS411N GDSC1; CTRP2 -7.3959 -0.398 -7.9662 44.4789
CL-34 CTRP1 -6.9364 -0.8741 -7.7178 61.7677
SW403 CTRP1 -6.7318 42.4903 -24.2061 59.1298
SNU-407 GDSC1; CTRP2 -6.6689 -3.6823 -6.6785 43.5718
LS180 GDSC1; GDSC2; CTRP2; CTRP1 -6.5681 -4.1834 -6.5732 38.7653
HCT 15 GDSC1; GDSC2; CTRP2 -6.2055 -2.0952 -6.2833 48.1044
C2BBe1 GDSC1; CTRP2 -5.4085 1.231 -6.0582 43.8626
LS513 GDSC1; GDSC2; CTRP2 -5.3751 -2.4951 -5.4178 31.8378
CaR-1 GDSC1; GDSC2 -5.3376 -1.8244 -5.4472 40.508
SNU-C4 CTRP2; CTRP1 -5.2552 -3.9072 -5.2553 41.6993
SW620 GDSC1; GDSC2; CTRP2; CTRP1 -5.2164 -3.0958 -5.2195 35.3098
SW948 GDSC1; GDSC2; CTRP2; CTRP1 -5.174 -1.7051 -5.236 41.3273
NCI-H747 GDSC1; CTRP2 -4.9391 -1.1229 -5.0492 39.902
OUMS-23 CTRP2 -4.8922 -1.6555 -5.2445 20.8912
HT-55 GDSC1; CTRP2; CTRP1 -4.6585 -2.6017 -4.6629 32.1453
SNU-C1 GDSC1; GDSC2; CTRP2 -4.56 -1.4167 -4.6176 37.2455
SNU-1040 GDSC1; CTRP1 -4.3118 -2.1088 -4.3386 48.2531
HCC-56 CTRP2 -4.2495 -3.5598 -4.2495 34.9947
RKO GDSC1; GDSC2; CTRP2; CTRP1 -4.1669 -2.0246 -4.1766 29.3687
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 -4.1203 -1.5004 -4.1524 34.2393
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 -3.9582 -3.3642 -3.9582 23.3523
SNU-C5 GDSC1; CTRP1 -3.3385 7.6872 -6.8871 44.7191
LS1034 GDSC1; GDSC2; CTRP2 -3.2805 1.3455 -3.7702 30.176
GP5d GDSC1 -3.1984 7.4389 -6.6334 46.0886
NCI-H508 GDSC1; GDSC2; CTRP2; CTRP1 -3.0901 0.1293 -3.2596 23.7209
T84 GDSC1; GDSC2; CTRP2 -2.9864 1.1057 -3.3798 27.9213
SW480 CTRP1 -2.8983 -0.3009 -3.6519 19.7672
CL-11 GDSC1; CTRP2 -2.8409 0.0078 -2.9685 22.1825
SNU-C2A CTRP2; CTRP1 -1.6845 -0.0932 -1.6846 30.64
SW626 GDSC1 -1.5696 13.7081 -8.2023 41.5738
MDST8 GDSC1; CTRP2; CTRP1 -1.4482 2.0337 -2.0113 15.6419
HCC2998 GDSC1 -1.431 14.4368 -8.4431 41.4112
SNU-81 GDSC1; GDSC2; CTRP2; CTRP1 -1.3054 3.0991 -2.7373 12.6597
SW1417 GDSC1; GDSC2; CTRP2 -0.9716 3.0953 -1.9421 16.7867
COLO205 GDSC1; CTRP2 -0.9165 -0.0545 -0.9858 5.6206
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 -0.8378 -0.1041 -0.8881 5.0968
SNU-61 GDSC1; CTRP1 -0.8101 0.4534 -1.0389 10.4638
SNU-C2B GDSC1; GDSC2 -0.5775 8.5487 -4.7647 22.484
CW-2 GDSC1; GDSC2; CTRP1 0.0772 2.3189 -1.0958 5.0375
CL-40 CTRP1 0.1643 4.7303 -3.7301 8.8179
SNU-175 CTRP1 0.2344 3.4143 -3.0989 4.1097
SK-CO-1 GDSC1; GDSC2; CTRP2 0.2868 10.8197 -5.1727 18.0044
DiFi GDSC1 0.4454 9.7338 -4.5009 27.1955
SW1463 GDSC1; GDSC2 0.5826 9.0919 -4.0701 17.2932
DLD-1 CTRP2 0.6266 1.8109 -2.3193 0.0304
SW837 GDSC1; GDSC2 0.8534 9.0007 -3.8104 15.7075
HT115 GDSC1; GDSC2; CTRP1 0.9422 9.7366 -4.1071 20.8409
SNU-283 GDSC2 0.9776 5.4288 -1.949 9.6806
SW1116 GDSC1; GDSC2 1.0945 10.7239 -4.4793 17.7838
CCK-81 GDSC1; GDSC2 1.3959 5.6652 -1.7707 5.7995
LS123 GDSC1; GDSC2; CTRP2; CTRP1 2.3961 8.1104 -1.4695 6.7885
SNU-503 CTRP2 2.875 4.886 0.3084 0.7399
GP2d CTRP2 3.3365 5.3052 0.3465 0.4248
KM12 GDSC1; CTRP2; CTRP1 3.3817 4.8655 0.5221 0.1111
COLO 678 GDSC1; CTRP2; CTRP1 3.6787 5.5343 0.3971 0.2312
⏷ Show the Full List of 61 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 -0.2159 8.8575 -4.61 21.0811
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 GDSC1; CTRP2 -8.2227 -6.3214 -8.2228 61.4742
HLE GDSC1; GDSC2 -8.1134 -5.4251 -8.1166 60.9417
SNU-182 CTRP2 -7.8728 -5.1027 -7.8954 39.5819
JHH-7 GDSC1; GDSC2 -7.2056 -5.136 -7.2065 54.2232
SNU-449 GDSC1; GDSC2; CTRP2; CTRP1 -6.4392 -3.7761 -6.4393 60.3145
Li-7 CTRP2 -5.2791 -2.9635 -5.3645 22.5185
HuH-6 CTRP2 -5.1938 -2.4015 -5.2131 35.2268
SNU-423 GDSC1; GDSC2; CTRP2 -4.5415 -1.9403 -4.5633 37.0117
SK-HEP-1 GDSC1; GDSC2; CTRP2 -4.1973 -3.3218 -4.1973 34.6466
JHH-4 GDSC1; CTRP2 -3.8636 -1.6681 -3.8788 32.4728
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 -2.8875 10.693 -7.9094 31.212
SNU-475 CTRP2 -2.7095 9.9273 -6.8361 35.8623
JHH-6 GDSC1; CTRP2; CTRP1 -1.6956 -1.0047 -1.6956 35.4388
Hep-G2 CTRP2; CTRP1 -1.6826 5.6755 -3.828 22.0657
PLC/PRF/5 CTRP2 -1.6016 4.7088 -3.3031 23.5888
SNU-398 GDSC1; CTRP2; CTRP1 -0.2275 10.9631 -5.0382 22.6052
Hep-G2/C3A GDSC1 0.0192 20.1074 -10.0377 39.3448
HuH-1 GDSC1; CTRP2 1.5308 6.0368 -1.0908 7.8138
JHH-2 GDSC1; GDSC2; CTRP2 1.8866 6.1102 -0.8592 6.2617
Huh-7 GDSC1 2.747 4.2571 -0.4827 0.1564
SNU-387 GDSC1; GDSC2; CTRP2 3.0651 4.6296 0.4871 0.2542
JHH-5 CTRP2 3.6392 5.3857 0.4348 0.1881
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 222 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SBC-3 GDSC1; GDSC2 -10.1271 -8.3629 -10.1271 76.1015
EMC-BAC-2 GDSC1 -10.0748 3.5268 -12.1259 72.1274
NCI-H82 GDSC1; GDSC2; CTRP1 -9.953 -8.4534 -9.953 81.7992
Ms-1 GDSC1; GDSC2 -9.7118 -7.9322 -9.7118 73.0196
NCI-H446 GDSC1 -9.6422 -6.9445 -9.6431 96.4288
COR-L51 CTRP1 -9.521 -7.1632 -9.5228 92.9647
COR-L279 GDSC1; GDSC2; CTRP1 -9.3481 -7.2602 -9.3481 78.4485
Lu-99A GDSC1 -9.3432 -1.0834 -9.9224 78.8374
NCI-H209 GDSC1 -9.3222 -5.2853 -9.345 91.0325
NCI-H1155 GDSC1; CTRP2 -9.2228 -8.4221 -9.2228 54.4126
NCI-H64 GDSC2 -9.0097 -7.2151 -9.0112 57.0413
NCI-H810 GDSC1; GDSC2; CTRP1 -9.0059 -7.8403 -9.0059 76.6638
NCI-H211 GDSC1; GDSC2; CTRP2 -8.9344 -7.6286 -8.9344 52.711
CPC-N GDSC1; GDSC2 -8.8947 -8.0308 -8.8947 66.9427
NCI-H524 GDSC1; GDSC2 -8.5037 -7.0461 -8.5037 63.9966
IST-SL1 GDSC1; GDSC2 -8.2332 -6.2565 -8.2334 81.3924
SCLC-21H CTRP1 -8.2225 -5.0155 -8.2615 80.0489
NCI-H1092 GDSC1; CTRP2 -8.1846 -6.1539 -8.1847 61.2162
DMS 114 GDSC1; GDSC2; CTRP2 -8.1626 -7.0841 -8.1626 61.0808
Lu-135 GDSC1 -8.0342 -5.7547 -8.0351 91.2286
Lu-139 GDSC1; GDSC2 -7.9566 -5.7619 -7.9573 59.8491
SHP-77 GDSC1; GDSC2; CTRP2 -7.9545 -6.1868 -7.9546 46.9301
NCI-H146 GDSC1; GDSC2; CTRP2 -7.8643 -5.5404 -7.8648 59.0722
NCI-H322 CTRP2 -7.856 -3.9867 -7.8789 58.7603
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 -7.8101 -5.1917 -7.8115 58.6914
HCC33 GDSC2 -7.745 -4.9004 -7.7515 75.6042
NCI-H1876 GDSC1; CTRP1 -7.6749 -3.18 -7.7688 76.5016
NCI-H1048 GDSC1; CTRP1 -7.6566 -2.1054 -7.6893 85.3562
MOR/CPR CTRP2 -7.5968 -5.5722 -7.6008 37.6863
NCI-H720 GDSC1 -7.5396 -4.7821 -7.5458 86.025
NCI-H526 GDSC1; GDSC2 -7.4355 -5.7292 -7.4356 55.9584
NCI-H520 GDSC1; GDSC2; CTRP2 -7.3485 -3.2131 -7.3926 55.4407
RERF-LC-A1 CTRP2 -7.2937 -5.3406 -7.298 35.668
NCI-H2141 GDSC1; CTRP2; CTRP1 -7.2793 -5.1653 -7.2797 55.1877
NCI-H69 GDSC1; GDSC2; CTRP2 -7.2778 -5.455 -7.2781 42.9384
NCI-H510A GDSC2 -7.2723 -6.2148 -7.2723 72.9603
A-427 GDSC1; GDSC2 -7.2254 -5.3153 -7.2259 72.1445
NCI-H740 GDSC2 -7.2175 -4.854 -7.2201 71.6331
NCI-H2227 GDSC1; GDSC2 -7.2041 -5.5734 -7.2042 72.1157
NCI-H1436 GDSC1; GDSC2 -7.1968 -0.7628 -7.6597 64.989
SBC-1 GDSC1; GDSC2 -7.1916 -5.6813 -7.1917 72.048
NCI-H841 GDSC1; GDSC2; CTRP2; CTRP1 -7.1725 -3.2424 -7.2093 54.3443
NCI-H1694 GDSC1; CTRP2; CTRP1 -7.08 -2.3749 -7.1762 53.6349
NCI-H1105 GDSC1; GDSC2; CTRP2; CTRP1 -7.068 -3.3445 -7.0968 53.6928
NCI-H835 GDSC1; GDSC2 -7.0166 -5.5405 -7.0166 52.8079
IST-SL2 GDSC1; GDSC2 -6.9971 -5.1719 -6.9975 69.9877
ChaGo-K-1 GDSC1; GDSC2; CTRP2; CTRP1 -6.9892 -4.6884 -6.9892 63.2056
NCI-H2106 CTRP2 -6.9686 -4.2738 -7.0087 33.6195
NCI-H748 GDSC2 -6.9094 -4.6612 -6.9118 68.8426
NCI-H596 GDSC1; CTRP1 -6.8517 -5.2237 -6.8519 76.1349
LB647-SCLC GDSC1; GDSC2 -6.8195 -3.9737 -6.8328 67.4032
NCI-H250 GDSC2 -6.8076 -5.4281 -6.8076 68.2738
NCI-H2030 GDSC1; GDSC2; CTRP2; CTRP1 -6.8067 -3.1027 -6.8651 40.3076
COR-L321 GDSC1; GDSC2 -6.8054 -4.8252 -6.8063 68.0299
NCI-H1770 GDSC1; GDSC2 -6.7562 -4.0312 -6.7668 66.9499
HCC1438 CTRP2 -6.7204 -2.9597 -6.7576 51.43
NCI-H838 GDSC1; GDSC2; CTRP2 -6.6834 -4.4038 -6.6847 51.2181
DMS 273 GDSC1; CTRP2; CTRP1 -6.6662 -3.6514 -6.6667 61.4846
NCI-H322M GDSC1 -6.5001 -1.5839 -6.7325 71.1873
Lu-134-A GDSC1; GDSC2 -6.4246 -4.5767 -6.4254 64.3514
NCI-H23 GDSC1; CTRP2; CTRP1 -6.3869 -1.2636 -6.4211 59.684
NCI-H1963 CTRP1 -6.3605 -1.0943 -7.0199 58.1041
NCI-H1355 GDSC1; GDSC2; CTRP1 -6.3295 -2.1041 -6.3398 61.8266
NCI-H1568 GDSC1; CTRP2; CTRP1 -6.2441 -2.2631 -6.2512 59.1911
EMC-BAC-1 GDSC1; GDSC2 -6.169 -1.6474 -6.3647 59.8811
NCI-H1341 GDSC1; CTRP2 -6.1195 -3.437 -6.1266 47.4715
HCC366 GDSC1; GDSC2; CTRP2 -5.8927 -1.9229 -6.0261 35.1431
Lu-165 GDSC1; GDSC2 -5.8206 -3.7773 -5.8242 43.8181
NCI-H1693 GDSC1; CTRP2 -5.7205 -2.2518 -5.7646 44.8932
COR-L95 GDSC1; GDSC2; CTRP2 -5.7096 -2.3923 -5.7447 44.8045
DMS 53 GDSC1; CTRP2 -5.7042 -3.907 -5.7047 44.6937
HCC78 GDSC1; GDSC2; CTRP2 -5.5927 -2.2373 -5.6691 33.2188
NCI-H1734 GDSC2; CTRP2 -5.5742 -3.4867 -5.5795 32.9022
COR-L303 GDSC2 -5.5403 -3.0156 -5.5586 55.4469
NCI-H2803 GDSC1; GDSC2 -5.5143 1.2494 -6.4002 53.5662
COR-L88 GDSC1; GDSC2; CTRP1 -5.48 -1.2727 -5.4955 57.3126
COR-L32 GDSC1; GDSC2 -5.2723 -2.4853 -5.3115 52.7953
NCI-H1581 GDSC1; GDSC2; CTRP2 -5.269 -0.9932 -5.5127 31.7991
LK2 CTRP2 -5.257 -2.1312 -5.2916 41.8069
Calu-3 GDSC1; GDSC2; CTRP2; CTRP1 -5.2289 -1.7109 -5.2341 46.7514
Calu-6 GDSC1; CTRP2; CTRP1 -5.1745 -2.6849 -5.1748 47.2274
HCC1588 CTRP2 -5.171 -2.6977 -5.2922 21.9224
HCC95 CTRP2 -5.0623 -0.0487 -6.0024 24.1536
RERF-LC-MS GDSC1; GDSC2; CTRP2 -5.0064 -2.2684 -5.0263 40.1009
Lu-65 GDSC1; GDSC2; CTRP2 -4.9024 -3.2361 -4.903 39.349
VMRC-LCD GDSC1; GDSC2; CTRP2; CTRP1 -4.8913 -1.0762 -4.9025 52.1869
DMS 79 GDSC1; GDSC2; CTRP2 -4.8458 -2.6773 -4.8602 28.632
HCC44 GDSC1; GDSC2; CTRP2 -4.8372 -2.5444 -4.8572 28.5978
HCC1359 CTRP1 -4.7708 -2.5104 -4.8948 41.0516
COLO 668 GDSC1; GDSC2; CTRP2; CTRP1 -4.6861 -1.2106 -4.6928 51.1234
NCI-H1755 GDSC1; GDSC2; CTRP1 -4.6851 -2.7293 -4.6943 35.295
NCI-H1703 GDSC1; GDSC2; CTRP2 -4.667 -1.7765 -4.702 37.8881
NCI-H2461 GDSC1; GDSC2 -4.6123 2.8411 -6.018 38.641
HOP-62 GDSC1; CTRP2 -4.5746 2.3673 -5.5053 39.4519
NCI-H1184 CTRP2 -4.4496 -2.2229 -4.4589 30.9731
NCI-H1915 GDSC1; CTRP2; CTRP1 -4.3348 -1.4043 -4.3371 49.2864
NCI-H1435 GDSC1; GDSC2; CTRP2; CTRP1 -4.3297 -0.9082 -4.3372 43.343
LCLC-103H GDSC1; GDSC2; CTRP2 -4.3213 -1.2736 -4.4392 25.8493
NCI-H2286 CTRP1 -4.3053 1.2722 -4.4292 88.848
NCI-H2405 GDSC1; CTRP2; CTRP1 -4.127 0.7874 -4.1994 41.8706
RERF-LC-Ad2 CTRP2 -4.0735 0.8475 -4.496 35.1195
NCI-H3122 GDSC2 -4.0451 -0.8187 -5.2176 14.2573
NCI-H1437 GDSC1; GDSC2; CTRP1 -4.0221 -1.842 -4.0223 60.4277
NCI-H1651 GDSC1; GDSC2; CTRP2 -4.0033 0.3178 -4.2903 34.264
NCI-H2810 GDSC1; GDSC2 -3.9404 -1.9877 -3.9612 39.6373
NCI-H2196 GDSC2; CTRP2 -3.9358 -1.9022 -3.9446 32.9328
NCI-H1975 GDSC1; CTRP1 -3.9227 1.908 -4.0967 65.495
LC-1/sq-SF CTRP2 -3.9164 -1.6035 -3.9359 32.8391
SBC-5 GDSC1; CTRP2 -3.6572 1.9134 -4.6386 24.6712
HCC2279 CTRP2 -3.5633 1.3649 -5.0855 16.673
NCI-H1299 GDSC1; GDSC2; CTRP2; CTRP1 -3.3907 1.6216 -3.5004 38.6172
NCI-H1930 CTRP1 -3.3259 -0.3827 -3.331 94.2123
LXF 289 GDSC1; CTRP2; CTRP1 -3.1196 -1.8329 -3.1196 37.7436
NCI-H2795 GDSC1; GDSC2 -3.0055 4.9076 -5.2561 30.8745
COR-L23 GDSC1; CTRP1 -2.9111 4.7008 -5.0669 40.1913
NCI-H1869 GDSC1; GDSC2; CTRP2 -2.7403 0.6199 -2.9848 25.7751
NCI-H2023 GDSC1; GDSC2; CTRP2; CTRP1 -2.732 -0.4266 -2.7902 21.3605
NCI-H1573 GDSC1; CTRP1 -2.6241 0.4896 -2.6366 58.6399
SK-MES-1 GDSC1; CTRP2 -2.5474 4.0507 -3.9845 28.5691
A-549 GDSC1; GDSC2; CTRP2; CTRP1 -2.4914 -1.1854 -2.4914 34.3062
HCC827 GDSC1; CTRP2; CTRP1 -2.4512 0.5377 -2.8391 15.6872
NCI-H1339 CTRP2 -2.3348 0.0533 -2.4315 22.5599
LCLC-97TM1 GDSC1; CTRP2; CTRP1 -2.322 0.7051 -2.3349 34.0925
KNS-62 GDSC1; GDSC2; CTRP2; CTRP1 -2.2306 0.3474 -2.2353 38.2574
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 -1.9328 -0.4738 -1.9486 19.6037
BEN GDSC1; GDSC2; CTRP2 -1.8697 1.4296 -2.5525 13.2716
RERF-LC-Ad1 CTRP2 -1.815 0.6783 -3.1488 4.8256
NCI-H2009 GDSC1; GDSC2; CTRP2; CTRP1 -1.7821 2.3468 -1.8782 31.3016
NCI-H727 GDSC1; GDSC2; CTRP2 -1.7079 8.1132 -5.5552 22.9383
RERF-LC-KJ GDSC1; CTRP1 -1.662 -0.4857 -1.662 51.4656
EPLC-272H GDSC1; CTRP1 -1.5318 0.0845 -1.532 50.4686
LK-2 GDSC1; GDSC2 -1.4994 12.9286 -7.7527 32.6247
NCI-H1373 CTRP2 -1.4851 2.9022 -2.3936 16.9768
HCC2108 CTRP2; CTRP1 -1.4224 6.0712 -5.5253 13.8454
HCC1833 CTRP2; CTRP1 -1.3976 3.2813 -4.116 8.124
EBC-1 GDSC1; CTRP2 -1.1509 2.9568 -2.0677 15.1307
NCI-H2073 CTRP1 -1.0397 1.3133 -2.8942 5.4624
LC-2/ad GDSC1; GDSC2 -0.9592 3.4657 -2.5853 19.1592
NCI-H647 GDSC2; CTRP2 -0.8216 2.1892 -1.4037 14.2872
NCI-H1836 GDSC1; GDSC2; CTRP1 -0.7531 12.3327 -6.8046 33.7867
NCI-H2373 GDSC1 -0.6143 21.3872 -11.2098 41.7333
UMC-11 GDSC1 -0.5817 3.3077 -2.1606 18.938
COLO 699 CTRP2; CTRP1 -0.4702 12.4311 -7.9429 20.2249
NCI-H522 GDSC1; GDSC2 -0.4425 15.6103 -8.1769 31.059
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 -0.2144 1.0462 -0.711 3.0376
NCI-H1792 GDSC1; GDSC2; CTRP2; CTRP1 -0.0874 1.4376 -0.0883 23.7522
NCI-H345 GDSC1; GDSC2 -0.0235 1.2609 -0.6502 4.1852
NCI-H1838 GDSC1; CTRP2 0.0171 9.017 -4.4942 16.3189
NCI-H2291 GDSC1; GDSC2; CTRP2 0.0691 2.5646 -1.2252 4.4437
NCI-H661 GDSC1 0.1105 30.5107 -15.1634 42.6767
NCI-H2804 GDSC1; GDSC2 0.1702 7.1383 -3.4283 19.9396
NCI-H1650 GDSC1 0.1854 11.005 -5.3487 30.825
NCI-H290 GDSC1; GDSC2 0.2133 11.8481 -5.7473 28.5182
PaCa-3 GDSC1; GDSC2 0.2148 5.6453 -2.6458 12.0242
NCI-H2369 GDSC1 0.2601 10.9507 -5.2602 30.3264
NCI-H1944 GDSC1; CTRP2; CTRP1 0.2749 5.5057 -0.2906 26.6402
LUDLU-1 CTRP2 0.3824 2.4552 -0.2898 6.7488
NCI-H2347 GDSC1 0.67 10.5303 -4.7177 27.2621
NCI-H1688 GDSC1 0.6872 16.5671 -7.718 34.6832
CAL-12T GDSC1; GDSC2; CTRP2; CTRP1 0.7283 8.2969 -3.5582 11.9317
NCI-H3255 GDSC1; GDSC2; CTRP1 0.7297 2.8335 -0.8645 3.6797
NCI-H358 GDSC1; GDSC2; CTRP2 0.752 5.278 -2.0415 6.4045
NCI-H2172 GDSC1; GDSC2; CTRP2; CTRP1 0.7674 3.3075 -0.3528 5.2438
COR-L105 GDSC1; GDSC2; CTRP2 0.8114 6.4257 -1.8716 12.3955
RERF-LC-Sq1 GDSC1 0.8569 6.7343 -2.6824 17.0499
Lu-99 CTRP2 0.8653 3.0911 -2.6768 0.4092
LOU-NH91 GDSC1 0.8736 7.425 -3.0119 18.9188
NCI-H2228 GDSC1 0.909 6.8416 -2.6959 16.9659
NCI-H2029 GDSC1; GDSC2; CTRP2; CTRP1 1.0955 6.3856 0.3103 22.9978
NCI-H292 GDSC1; GDSC2; CTRP2 1.114 7.3311 -2.7836 8.578
NCI-H1304 GDSC1 1.1985 7.1673 -2.6405 15.7358
NCI-H2171 GDSC2 1.2601 5.8607 -1.9582 9.08
NCI-H2869 GDSC1; GDSC2 1.3033 5.6192 -1.8116 8.1257
NCI-H1781 GDSC1; CTRP1 1.3072 4.5001 -1.2762 5.5309
SW1271 GDSC1; GDSC2 1.327 4.2612 -1.1524 3.1653
NCI-H2085 GDSC1; GDSC2 1.3282 12.5097 -5.1853 19.7664
NCI-H2126 CTRP2 1.3495 5.8699 -1.1502 7.146
NCI-H1395 CTRP2 1.3732 4.5653 -0.482 5.5485
NCI-H2135 GDSC1; GDSC2 1.4191 8.1483 -2.9605 14.2622
HCC1171 CTRP2 1.4508 3.2922 -2.5316 0.0964
NCI-H1993 GDSC1; GDSC2 1.4632 10.7016 -4.1857 15.9707
ABC-1 GDSC1; GDSC2 1.4843 6.966 -2.3369 10.7446
NCI-H1666 GDSC1; GDSC2; CTRP2; CTRP1 1.5323 6.6201 0.6942 18.3789
NCI-H2722 GDSC1 1.5812 3.4227 -0.6421 1.4784
NCI-H1648 GDSC1; GDSC2 1.6188 4.8133 -1.2288 3.1072
NCI-H2087 GDSC1; GDSC2 1.6618 7.3011 -2.3756 8.0736
NCI-H187 GDSC1 1.6692 3.7208 -0.7222 1.8057
NCI-H2591 GDSC1 1.7452 8.513 -2.9043 15.711
T3M-10 CTRP2; CTRP1 1.7886 6.8201 -1.2818 8.1624
NCI-H2170 GDSC1; CTRP2 1.7914 5.5714 -0.6643 5.6108
SK-LU-1 GDSC1; GDSC2; CTRP2; CTRP1 1.798 4.5702 -0.1718 3.053
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 1.808 10.3716 -3.0306 12.7403
HCC2935 CTRP2; CTRP1 1.8369 5.4997 -0.5962 5.2588
NCI-H2595 GDSC1; GDSC2 1.839 10.6686 -3.8901 14.1349
NCI-H2122 GDSC1; CTRP2; CTRP1 1.8559 7.4417 -1.5383 7.7699
NCI-H2818 GDSC1; GDSC2 1.8873 15.1659 -6.0733 21.426
LC-1/sq GDSC1 1.9409 10.7559 -3.8587 20.0413
NCI-H2066 GDSC1; GDSC2 2.0454 4.1956 -0.737 0.8587
SW1573 GDSC1; CTRP2 2.0732 10.6541 -2.9644 12.349
NCI-H513 GDSC1 2.1061 4.9833 -1.0326 2.9797
NCI-H2731 GDSC1; GDSC2 2.1464 4.8784 -0.9678 1.5326
NCI-H847 GDSC1; GDSC2 2.2295 3.5976 -0.4402 0.1288
HOP-92 GDSC1; CTRP2 2.2733 6.9877 -1.0105 6.2836
HCC15 GDSC1; CTRP2; CTRP1 2.2844 4.5239 -0.7593 0.6076
NCI-H196 GDSC1; CTRP2 2.4429 10.7447 -3.4979 9.2587
NCI-H2444 GDSC1; GDSC2; CTRP2 2.5009 3.6915 0.6077 0.1871
IA-LM GDSC1; GDSC2; CTRP2 2.7088 4.6231 0.3369 0.7645
Sq-1 CTRP2; CTRP1 2.7557 4.6624 0.3429 0.612
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 2.9519 8.8636 -1.4481 7.0483
NCI-H226 GDSC1; GDSC2; CTRP2 3.0356 4.2996 0.593 0.0935
NCI-H1563 GDSC1; CTRP2 3.1053 4.8995 0.4036 0.3983
Calu-1 CTRP2 3.3056 4.7255 0.543 0.1199
NCI-H1793 GDSC1; CTRP2 3.336 5.4882 0.2769 0.5753
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 3.4426 8.7071 -1.0582 4.1885
NCI-H1623 GDSC1; CTRP2 3.5803 5.3792 0.4152 0.2286
DMS 454 CTRP2 3.6214 5.7712 0.2888 0.4329
HCC4006 CTRP2; CTRP1 3.6414 5.0957 0.5351 0.0808
HCC1195 CTRP2; CTRP1 3.7567 5.2263 0.531 0.0611
PC-14 GDSC1; GDSC2; CTRP2 3.8442 5.4818 0.4752 0.0921
EKVX GDSC1; GDSC2; CTRP2 4.0544 6.841 0.0651 0.7284
NCI-H650 GDSC1; CTRP2; CTRP1 6.8412 14.5773 1.6909 7.5281
Hs 888.Lu CTRP2 3.0357 7.9188 -0.9458 4.9793
⏷ Show the Full List of 222 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 -9.8894 -8.4747 -9.8894 74.4044
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -7.447 -4.5884 -7.4509 56.2671
COV318 CTRP1 -9.7282 16.4121 -15.1481 71.9583
A2780 GDSC1; GDSC2; CTRP1 -8.9071 -7.7436 -8.9071 67.0351
OVCAR-8 GDSC1; CTRP2; CTRP1 -8.7854 -7.177 -8.7854 55.5686
ONCO-DG-1 CTRP2 -8.7268 -6.915 -8.7272 45.2046
OVCAR-5 GDSC1; GDSC2; CTRP2 -8.154 -6.4443 -8.154 61.0204
OVMANA CTRP1 -8.0774 2.2684 -8.623 87.8441
OC 314 GDSC1; GDSC2; CTRP2 -7.7556 -6.1412 -7.7556 58.3663
DOV13 GDSC1; GDSC2; CTRP2 -7.7063 -4.4911 -7.7213 45.4945
COV434 CTRP2; CTRP1 -7.383 -3.5401 -7.4117 55.7176
ES2 CTRP2 -7.2157 -5.5386 -7.2172 35.1388
EFO-27 GDSC1; GDSC2; CTRP2; CTRP1 -6.4766 -2.2209 -6.5566 49.8479
OV7 CTRP2; CTRP1 -6.078 -2.6326 -6.112 47.2312
HEY A8 CTRP2; CTRP1 -5.8796 -4.6454 -5.8796 50.4809
OVK18 GDSC1; GDSC2; CTRP2; CTRP1 -5.871 -3.0837 -5.8822 39.0487
OVISE GDSC1; CTRP2 -5.8417 -3.5996 -5.8483 34.4843
TOV-21G GDSC1; CTRP2 -5.791 -1.0576 -5.9677 45.5575
JHOC-5 CTRP2; CTRP1 -5.7623 -1.9096 -6.1203 26.6822
IGROV-1 GDSC1; CTRP2; CTRP1 -5.7347 -4.2669 -5.7348 38.2448
OVKATE GDSC1; GDSC2; CTRP1 -5.5921 -3.2088 -5.6045 42.1271
EFO-21 GDSC1; GDSC2; CTRP2; CTRP1 -5.4864 -1.7964 -5.4927 55.2892
OAW42 GDSC1; CTRP2; CTRP1 -5.4262 -4.6327 -5.4262 42.8392
OVCAR-4 GDSC1; CTRP2; CTRP1 -4.9502 -2.8288 -4.9543 33.801
OVCAR-3 GDSC1 -4.7275 36.4708 -22.3109 50.9662
JHOS-2 GDSC1; GDSC2; CTRP2 -4.3092 -1.3454 -4.3608 35.5596
SNU-8 CTRP2 -3.9889 -2.1081 -4.133 14.1311
MCAS CTRP2 -3.9274 -2.5928 -3.9277 27.9821
OVSAHO CTRP2 -3.7495 0.0752 -4.6819 15.5474
TYK-nu GDSC1; CTRP2; CTRP1 -3.4666 -2.178 -3.4672 25.3662
Kuramochi GDSC1; GDSC2; CTRP2 -3.3531 6.2282 -6.2135 28.4663
RMUG-S CTRP1 -2.8166 8.6766 -7.9976 38.1171
COV644 CTRP2; CTRP1 -2.6074 3.8654 -3.9694 28.7016
JHOS-4 GDSC2; CTRP1 -2.5853 -1.2218 -2.5853 50.8801
OVTOKO GDSC1; CTRP2 -2.2391 4.8074 -4.454 20.6588
RMG-I GDSC1; GDSC2; CTRP1 -2.1863 5.4867 -4.7259 26.6397
TOV-112D GDSC1; CTRP2 -2.0229 6.5818 -4.5862 28.8711
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 -1.8144 3.8128 -3.1223 23.5258
COV362 CTRP2; CTRP1 -0.8364 1.4377 -1.1387 13.323
SNU-840 CTRP2; CTRP1 -0.6618 5.0168 -2.5188 15.6062
SNU-119 CTRP2 -0.245 5.5754 -4.3988 7.4364
OV56 GDSC1; CTRP2 -0.0126 4.5723 -1.6871 13.4055
ES-2 GDSC1 0.6993 32.1951 -15.5185 41.9277
Caov-4 GDSC1; GDSC2 1.1007 7.6071 -2.9297 11.516
FU-OV-1 GDSC1; GDSC2 1.105 7.6602 -2.9527 11.6085
OAW28 GDSC1; CTRP2 1.909 10.9138 -3.2212 15.5175
Caov-3 GDSC2; CTRP2; CTRP1 2.6864 5.3785 0.0051 1.5663
JHOM-1 CTRP2; CTRP1 2.8082 4.0978 0.5799 0.1757
SK-OV-3 GDSC1; GDSC2; CTRP2; CTRP1 7.1066 9.6327 4.169 0.8259
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 -7.1254 -5.7954 -7.1254 54.1661
Yamato-SS CTRP2 -6.421 -2.8244 -6.4558 49.4815
Rh30 GDSC1 -10.1933 1.7299 -11.6406 74.9623
Rh41 GDSC1; CTRP2 -9.8036 -9.0228 -9.8036 57.8392
EW-8 GDSC1 -9.3194 3.2163 -11.2002 71.0578
TTC-709 CTRP2 -8.6932 -6.7343 -8.6932 64.6025
G-402 GDSC1; CTRP2 -8.2639 -5.8942 -8.2643 61.7223
BT-16 CTRP2 -8.1742 -6.9155 -8.1742 61.158
G-401 GDSC1; CTRP2; CTRP1 -7.9476 -6.2738 -7.9476 68.2392
MES-SA GDSC1; CTRP2 -7.8827 -4.9887 -7.8858 59.1413
SK-UT-1 GDSC1; GDSC2; CTRP2 -7.8516 -4.6237 -7.8587 58.8832
A-204 GDSC1; CTRP2 -7.7941 -6.4082 -7.7941 58.6236
TE 441.T GDSC2 -6.9615 -5.2082 -6.9618 69.6774
RD GDSC1; CTRP2 -6.9433 -4.0378 -6.9498 52.9316
Tm87-16 CTRP2 -6.9172 -2.9412 -6.9622 52.691
KYM-1 GDSC1; GDSC2; CTRP2 -6.7927 -3.4255 -6.8115 51.9192
MFH-ino GDSC1; GDSC2 -6.6772 0.8547 -7.5371 50.1897
HT-1080 GDSC1; CTRP2; CTRP1 -6.4198 -4.3563 -6.4205 49.463
Hs 633.T GDSC1; GDSC2 -6.1011 0.647 -6.8456 46.7628
BT-12 CTRP2 -6.0602 -4.2354 -6.0606 47.0663
STS-0421 GDSC1; GDSC2 -5.045 2.3815 -6.2999 50.3934
GCT GDSC1; CTRP2 -4.8814 -2.454 -4.8921 39.241
Rh18 GDSC1; CTRP2 -4.6235 -3.4928 -4.6235 31.9341
SW872 GDSC1; GDSC2 -4.485 2.2364 -5.646 37.2755
SK-LMS-1 GDSC1; GDSC2; CTRP2 -3.7137 -1.0697 -3.7606 31.5792
Hs 729.T CTRP2 -2.4648 0.9609 -2.7706 24.1603
VA-ES-BJ GDSC1 0.9474 2.9049 -0.7594 3.3022
RKN GDSC1; GDSC2; CTRP2; CTRP1 2.4802 6.4812 -0.6269 3.7959
SW684 GDSC1; GDSC2 3.1545 13.5371 -4.3542 13.6461
SW982 GDSC1; GDSC2; CTRP2 6.0201 24.3392 -6.7968 19.4534
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 -3.0521 1.2825 -3.5025 28.5482
SYO-1 CTRP2 6.3557 24.9637 -6.8654 19.1722
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-270 GDSC1; GDSC2 -10.7991 -9.2347 -10.7991 81.116
TE-8 GDSC1 -9.9272 -6.7336 -9.9303 95.7409
TE-15 GDSC1; GDSC2 -8.6688 -6.5704 -8.669 65.1866
EC-GI-10 GDSC1; CTRP2 -8.1671 -6.6975 -8.1671 61.1099
KYSE-180 GDSC1; CTRP2 -7.3729 -2.6837 -7.5037 43.7494
T.T GDSC1; GDSC2 -7.1559 -1.6787 -7.4235 53.3521
OE19 GDSC1; CTRP2 -7.0908 -1.7293 -7.2619 53.5849
KYSE-30 CTRP2 -6.7272 -5.9804 -6.7272 51.5121
TE-9 GDSC1; GDSC2; CTRP2 -6.6802 -5.4604 -6.6802 39.4118
COLO 680N GDSC1; GDSC2; CTRP2 -6.2871 -3.6486 -6.2998 37.1293
TE-1 GDSC1; CTRP2 -5.9454 -4.3425 -5.9455 39.441
TE-14 CTRP2 -5.8771 -2.8449 -5.8959 45.882
KYSE-510 GDSC1; GDSC2; CTRP2 -5.5034 -3.519 -5.5047 43.3575
TE-4 GDSC1 -4.8991 0.7571 -5.571 57.2734
KYSE-450 GDSC1; GDSC2; CTRP2; CTRP1 -4.734 -3.3514 -4.734 51.3799
OE33 GDSC1; GDSC2; CTRP2 -4.4585 0.3224 -4.7866 37.3434
KYSE-70 GDSC1; GDSC2; CTRP2 -4.1417 -3.4761 -4.1417 29.1981
OE21 GDSC1; CTRP2 -3.5457 0.7514 -3.8952 31.4579
KYSE-520 GDSC1; CTRP2 -3.3456 1.7301 -3.9603 31.0017
TE-5 GDSC1; GDSC2; CTRP2 -3.0625 1.1318 -3.4703 28.4723
KYSE-140 CTRP2; CTRP1 -2.3952 -1.4784 -2.3952 33.869
KYSE-410 CTRP2; CTRP1 -0.139 1.94 -0.1467 24.0061
TE-11 GDSC1; GDSC2; CTRP2 0.255 7.1319 -2.707 16.8743
TE-6 GDSC1 0.4857 22.9398 -11.0676 39.3287
TE-10 GDSC1; GDSC2; CTRP2 0.9207 4.0235 -1.3057 3.4938
KYSE-150 GDSC1; CTRP2 2.9132 4.5167 0.4681 0.3414
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ACC-MESO-1 CTRP2 -7.3827 -1.5146 -8.0019 37.941
NCI-H28 GDSC1; GDSC2; CTRP2; CTRP1 -4.8891 -2.1275 -4.89 45.2021
MSTO-211H GDSC2; CTRP2; CTRP1 -2.8892 -0.9388 -2.8894 36.6806
MPP 89 GDSC1; GDSC2; CTRP2 -1.631 3.9832 -3.0081 22.6062
IST-Mes1 GDSC1; GDSC2; CTRP2 1.384 10.2113 -3.2896 16.7386
NCI-H2052 CTRP2; CTRP1 1.7819 4.4834 1.6217 15.505
JL-1 CTRP2 3.0922 4.6949 0.474 0.2686
NCI-H2452 GDSC1; GDSC2; CTRP2 3.7558 5.534 0.4257 0.1501
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 -5.5413 5.2454 -7.9905 57.3902
PaCa-3 CTRP2; CTRP1 -4.4845 -3.7782 -4.4845 50.0712
DU145 GDSC1; GDSC2; CTRP2 -4.3257 -1.1895 -4.3925 35.7172
22Rv1 GDSC1; GDSC2; CTRP2 -2.1052 4.9897 -4.4105 20.2185
LNCaP clone FGC GDSC1; CTRP2 -1.5324 1.8987 -2.0524 18.7551
NCI-H660 GDSC2 1.6316 3.8019 -0.775 1.7382
VCaP GDSC1; GDSC2; CTRP2 1.8326 6.5215 -1.1013 7.346
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -5.9289 -5.1891 -5.9289 26.5585
A-253 GDSC1; CTRP2 3.4185 5.2329 0.4058 0.2867
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 0.0305 13.8988 -6.924 31.9272
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GSS CTRP2 -10.3776 -9.8295 -10.3776 56.204
HGC-27 GDSC1; CTRP2 -10.1439 -7.5808 -10.1441 74.0094
SNU-16 CTRP2 -9.7577 -8.6686 -9.7577 71.7133
HSC-39 GDSC1; GDSC2 -9.3749 -8.1199 -9.3749 70.5525
23132/87 GDSC1; CTRP2 -8.2999 -5.6525 -8.3024 48.9697
SNU-1 GDSC1; CTRP2 -7.6738 -4.2655 -7.6854 57.6873
ECC12 GDSC2; CTRP2 -7.6079 -4.7232 -7.6159 44.9023
NCC-StC-K140 CTRP2 -7.2184 6.0679 -13.7184 37.0841
MKN28 GDSC2 -7.151 -4.8027 -7.2088 38.6848
SNU-620 CTRP2 -7.1314 -4.6047 -7.1564 34.6543
TGBC11TKB GDSC1; GDSC2 -6.869 -5.0567 -6.8693 51.6959
GCIY GDSC2 -6.7433 -4.5085 -6.8113 34.6642
MKN45 GDSC1; GDSC2; CTRP2 -6.505 -4.1299 -6.5103 38.3934
SNU-216 CTRP2 -6.4617 -3.4828 -6.4727 49.7438
RF-48 GDSC1; GDSC2 -6.2717 -3.1483 -6.3058 47.2542
NCI-N87 GDSC1; GDSC2; CTRP2 -5.8533 -3.147 -5.8743 34.5947
MKN1 GDSC1; GDSC2; CTRP2 -5.7839 -4.8826 -5.7839 34.124
SCH GDSC1; GDSC2 -5.4179 -2.1974 -5.4888 54.0826
LMSU CTRP2 -5.2108 -3.122 -5.2135 41.4115
SNU-601 CTRP2 -4.7694 -1.885 -4.8014 38.56
KATO III GDSC1; GDSC2; CTRP2 -4.7248 1.605 -5.4227 39.8775
HuG1-N CTRP2 -4.6882 0.1024 -4.9877 38.7502
SNU-668 CTRP2 -4.1651 -0.7161 -4.7865 17.0763
SNU-5 GDSC1; CTRP2 -3.8477 -1.1828 -3.9453 22.9941
GSU CTRP2 -3.7792 -2.0862 -3.9097 12.6866
TMK-1 GDSC1; GDSC2 -3.5224 -1.1453 -3.6028 35.7305
SH-10-TC CTRP2; CTRP1 -3.2779 1.564 -3.3759 43.9116
NUGC-3 GDSC1; CTRP2 -3.1909 -0.2963 -3.296 24.1031
MKN74 CTRP2; CTRP1 -3.0359 1.5967 -3.1247 37.5488
IM95 GDSC1; CTRP2 -2.62 1.8548 -3.2132 26.202
Hs 746.T GDSC1; CTRP2 -2.611 0.3123 -2.7766 24.6392
MKN7 GDSC1; GDSC2; CTRP2; CTRP1 -2.4926 0.583 -2.5053 39.6514
OCUM-1 GDSC2; CTRP2 -2.2563 7.0516 -5.0357 31.9705
NUGC-4 GDSC1; CTRP2; CTRP1 -1.8718 2.4768 -1.9876 31.7534
AGS CTRP2; CTRP1 -1.297 2.1913 -3.4999 5.3967
Fu97 GDSC1; GDSC2; CTRP2; CTRP1 0.2794 6.457 -0.5962 24.2023
SNU-719 CTRP2 1.1837 2.9987 -2.5253 0.1235
RERF-GC-1B GDSC1 1.9317 4.9151 -1.0957 3.6543
SK-GT-2 GDSC1 2.7612 4.8062 -0.6688 0.5839
ECC10 GDSC1; GDSC2; CTRP2 2.8399 8.5918 -1.3936 5.9708
KE-39 CTRP2 5.0396 7.636 0.1617 0.2122
SNU-685 CTRP2 -6.5616 -4.5974 -6.562 50.4076
SNG-M GDSC1; GDSC2; CTRP2; CTRP1 -5.8437 -3.3919 -5.8438 50.3151
SNU-1077 CTRP2 -2.6396 3.0659 -5.0495 14.399
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CGTH-W-1 GDSC1; GDSC2; CTRP2 -8.5075 -7.1964 -8.5075 50.1925
FTC-238 CTRP2 -8.0366 -4.9033 -8.0417 60.1136
IHH-4 GDSC1; GDSC2 -7.7304 -5.6421 -7.7309 58.1616
SW579 CTRP2 -6.9727 -3.8825 -6.9824 53.1178
B-CPAP GDSC1; CTRP2 -6.8631 -5.2849 -6.8632 40.4911
CAL-62 GDSC1; GDSC2; CTRP2 -6.5448 -2.5432 -6.6422 38.8688
8505C GDSC1; CTRP2 -6.2687 -4.4493 -6.2696 36.9868
TT2609-C02 GDSC1; CTRP2 -5.1988 -3.3265 -5.2 41.327
8305C GDSC1; GDSC2; CTRP2 -4.2 -1.323 -4.3018 25.0848
K5 GDSC1; GDSC2 -3.3 2.4218 -4.4634 29.2804
TT GDSC1; GDSC2; CTRP2 -2.5844 2.4349 -3.7217 18.9908
BHT-101 GDSC1; CTRP2 -2.1624 -1.0182 -2.1785 12.8055
HTC-C3 GDSC1 -1.4675 11.6745 -7.1012 39.9268
KMH-2 GDSC1; GDSC2 -0.4762 2.0439 -1.4416 10.6107
WRO GDSC1; GDSC2 0.0088 11.8857 -5.9356 24.8297
FTC-133 GDSC1; CTRP2 0.0432 3.1024 -0.9261 10.1599
ASH-3 GDSC1 1.7835 3.0543 -0.414 0.3237
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 3.3641 5.1435 0.4171 0.2418
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H3118 GDSC1; GDSC2 -10.4338 -8.2165 -10.4338 78.0902
Ca9-22 GDSC1; GDSC2 -7.9464 -5.0863 -7.9522 59.6676
CAL-27 GDSC1; CTRP2 -7.303 -6.0191 -7.303 55.3499
PCI-04B GDSC1; GDSC2 -6.8668 -2.5502 -6.9825 65.7959
HSC-2 GDSC1; GDSC2; CTRP2; CTRP1 -6.5061 -4.5399 -6.5061 60.6763
FaDu CTRP2 -6.3169 -3.2016 -6.3331 48.7892
SNU-1066 CTRP2 -6.2595 -5.1489 -6.2597 28.7627
PCI-15A GDSC1; GDSC2 -6.0684 -4.1408 -6.0701 60.8024
YD-10B CTRP2 -6.0433 -5.0613 -6.0434 27.3214
SAS GDSC1; GDSC2 -6.031 -3.3773 -6.0473 45.4297
SNU-1214 CTRP2 -6.0065 -4.4015 -6.0121 27.0943
KOSC-2 GDSC1; GDSC2 -5.9025 -0.461 -6.3218 57.0206
JHU-029 GDSC1; GDSC2 -5.8791 -2.0237 -5.9981 57.9674
PE/CA-PJ34 (clone C12) CTRP2 -5.8217 -3.8353 -5.8227 45.4783
CAL-33 GDSC1; CTRP2 -5.7763 -1.9204 -5.8486 45.3092
JHU-011 GDSC1; GDSC2 -5.5492 -0.9101 -5.834 54.6965
PCI-38 GDSC1 -5.4913 2.0429 -6.6529 59.6766
HSC-3 GDSC1; CTRP2 -5.2009 -0.1495 -5.6358 31.9462
HO-1-N-1 GDSC1; GDSC2 -5.1212 -1.3036 -5.2946 39.0936
BB49-HNC GDSC1 -5.1137 3.127 -6.6631 56.7537
JHU-022 GDSC1; GDSC2 -4.5631 2.0246 -5.6492 37.6004
HSC-4 GDSC1; CTRP2 -4.3973 -3.9304 -4.3973 30.6495
SNU-1076 CTRP2 -4.341 -2.4181 -4.4474 16.3424
BICR 22 GDSC1; GDSC2; CTRP2 -3.8956 -2.2488 -3.8978 32.643
PE/CA-PJ49 CTRP2 -3.7838 -1.2714 -3.8181 32.0044
SCC-9 GDSC1; GDSC2; CTRP2; CTRP1 -3.703 -1.754 -3.7118 31.3807
BICR 78 GDSC1; GDSC2 -3.6844 2.733 -4.9952 32.4052
SKN-3 GDSC1 -3.54 13.5163 -9.8954 48.5509
BICR 18 CTRP2 -3.497 -1.2805 -3.5201 30.0553
BHY GDSC1; GDSC2; CTRP2 -3.3839 0.7616 -3.9258 21.6691
BICR 31 GDSC2; CTRP2 -3.1126 -1.3305 -3.1227 27.4493
SNU-46 CTRP2 -3.0229 1.3104 -4.5388 13.1809
PE/CA-PJ41 (clone D2) CTRP2 -2.6798 0.8068 -2.9648 25.5146
Detroit 562 GDSC1; CTRP2 -2.5141 9.2493 -6.8569 28.1114
OSC-20 GDSC1 -2.0581 20.3873 -11.9558 45.3209
HO-1-u-1 GDSC1; GDSC2 -2.008 7.8873 -5.7208 29.2232
PCI-06A GDSC1; GDSC2 -1.7968 9.0662 -6.1056 35.5208
LB771-HNC GDSC1 -1.6894 11.5124 -7.2183 40.8273
SCC-15 GDSC1 -1.6267 6.1206 -4.5029 35.1837
SNU-899 CTRP2 -1.269 3.7076 -4.2284 8.3667
PCI-30 GDSC1; GDSC2 -1.0143 11.1647 -6.4486 28.5817
UPCI-SCC-090 GDSC1 -0.9148 100.9223 -51.2255 48.3375
DOK GDSC1; GDSC2 -0.7212 9.4849 -5.3561 24.7885
BICR 10 GDSC1 -0.3178 36.9439 -18.7375 44.6176
SCC-25 GDSC1; GDSC2 0.2183 7.2231 -3.4313 19.8132
SNU-1041 CTRP2 0.6079 2.3727 -2.5167 0.2189
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 0.9251 5.1967 -1.1611 9.2295
OSC-19 GDSC1; GDSC2 0.9722 5.7617 -2.1162 10.679
KON GDSC1; GDSC2 1.7342 14.665 -5.9421 25.2911
BICR 16 CTRP2 1.8398 4.723 -0.2166 3.7043
BB30-HNC GDSC2 2.0635 4.0983 -0.6905 0.9508
BICR 6 CTRP2 2.7791 4.1636 0.5448 0.2424
BICR 56 CTRP2 3.3344 4.779 0.5349 0.124
SCC-4 GDSC1; GDSC2; CTRP2 8.3251 28.1819 -7.0782 17.2709
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JMSU-1 CTRP2 -10.3619 -9.6234 -10.3619 56.0995
KU-19-19 GDSC1; CTRP2 -7.2136 -6.1278 -7.2136 42.5586
BFTC-905 GDSC1; GDSC2; CTRP2 -6.6371 -3.5503 -6.6618 39.2253
CAL-29 GDSC1; CTRP2 -6.6088 -0.3385 -7.1228 40.1315
639V GDSC1; CTRP2 -6.3599 11.8479 -11.8016 44.1478
VM-CUB-1 CTRP2 -6.1615 -3.9847 -6.1892 28.2016
SW1710 GDSC1; GDSC2 -5.0752 2.4266 -6.3493 41.2157
647V GDSC1; CTRP2 -5.0209 -2.5569 -5.0313 40.1695
RT-112 GDSC1; GDSC2; CTRP2 -4.6812 -2.5485 -4.6868 32.2777
UM-UC-1 CTRP2 -4.2591 -3.2344 -4.2591 35.059
253J-BV CTRP2 -4.2375 2.7271 -6.3864 23.2591
UM-UC-3 GDSC1; GDSC2; CTRP2; CTRP1 -4.2302 -2.9567 -4.2302 42.8692
SCaBER CTRP2 -3.838 -2.711 -3.8381 32.2516
HT-1376 GDSC1; GDSC2; CTRP1 -3.8117 -0.2938 -3.8242 48.3628
TCCSUP GDSC1; CTRP2 -3.2752 1.8002 -4.1877 22.2423
KMBC-2 CTRP2; CTRP1 -3.0287 -0.7778 -3.0294 42.4345
HT-1197 GDSC1; CTRP2 -2.1151 3.6226 -3.3533 25.1951
5637 GDSC1; CTRP2; CTRP1 -1.9949 -0.9603 -1.9949 32.0501
J82 GDSC1; CTRP2 -1.8152 1.3416 -2.1719 20.0274
SW780 GDSC1 -0.9015 13.2827 -7.4068 38.5696
BC-3C CTRP2 3.0361 4.5821 0.4931 0.2528
T24 GDSC1; GDSC2; CTRP2 3.9377 10.92 -1.7778 7.0039
RT-4 GDSC1; CTRP2; CTRP1 4.2054 7.9061 2.8737 7.604
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEY GDSC1 -10.073 -7.5962 -10.0733 97.923
SiHa GDSC1 -9.1821 8.1682 -13.0169 65.5437
NEC8 GDSC1 -8.6817 -6.2267 -8.6826 93.9457
HEC-1 GDSC1 -8.534 15.4672 -15.6349 60.1222
NCC-IT GDSC2 -8.5138 -7.4077 -8.5138 52.1006
JEG-3 GDSC1; GDSC2 -7.9899 -3.609 -8.0611 74.2215
C-33 A GDSC1; GDSC2 -7.9052 -6.345 -7.9052 59.4934
TC-YIK GDSC1; GDSC2 -7.8625 -3.5799 -7.9303 58.5515
SiSo GDSC1 -7.5931 -0.0326 -8.2776 72.0594
NT2-D1 GDSC1; GDSC2 -7.2707 -3.1489 -7.3469 54.4502
HeLa GDSC1; CTRP2 -7.2588 -7.0315 -7.2588 46.8992
ME-180 GDSC1; GDSC2 -5.7838 1.8546 -6.9006 45.2085
JAR GDSC1; GDSC2 -5.5923 -2.9054 -5.6173 55.9062
HT-3 GDSC1 -4.8456 -2.0727 -4.8987 59.6602
LB831-BLC GDSC1; GDSC2 -4.4947 4.012 -6.3776 38.9045
C-4-I GDSC1 -4.2954 7.3226 -7.6547 51.3334
Ca Ski GDSC1; GDSC2 -3.92 0.9206 -4.5606 31.8535
BPH-1 GDSC1 -3.723 7.2899 -7.0743 48.6876
SKN GDSC1; GDSC2 -2.8496 5.4623 -5.3597 30.6826
MS751 GDSC1 -0.6999 12.4719 -6.8284 37.0193
DoTc2 4510 GDSC1; GDSC2 -0.4541 9.1917 -4.9795 22.9242
SW756 GDSC1 -0.2622 7.3388 -3.8901 27.2548
OVMIU GDSC1; GDSC2 -0.058 11.4589 -5.7779 24.5215
OV17R GDSC1; GDSC2 0.0195 6.146 -3.0568 18.5287
PWR-1E GDSC1 0.1775 26.5186 -13.1116 41.4522
CAL-39 GDSC1; GDSC2 0.1899 4.7489 -2.2181 10.1022
DSH1 GDSC1; GDSC2 0.5153 8.6762 -3.9165 16.8321
SW962 GDSC1; GDSC2 0.6514 6.8434 -2.8952 15.8761
OVCA420 GDSC1 0.6866 12.4369 -5.656 30.1589
UWB1.289 GDSC1; GDSC2 1.2647 6.7964 -2.4105 11.6643
JHOS-3 GDSC1; GDSC2 1.4542 8.4869 -3.101 14.895
KGN GDSC1; GDSC2 1.4654 12.1946 -4.9233 18.6224
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 1.664 5.8317 -1.6731 6.5783
SKG-IIIa GDSC1; GDSC2 1.97 13.7943 -5.3321 19.0243
OVCA433 GDSC1; GDSC2 2.0994 8.5204 -2.6631 11.1771
PEO1 GDSC1; GDSC2 2.3003 4.6055 -0.7842 0.8356
SW954 GDSC2 2.3502 3.97 -0.526 0.299
ACC-OV7 GDSC1; GDSC2 2.3526 15.4262 -5.851 23.6478
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7745).
2 Anticancer agent CHS-828 inhibits cellular synthesis of NAD. Biochem Biophys Res Commun. 2008 Mar 21;367(4):799-804.
3 Targeting the NAD(+) salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/-catenin signaling via increasing Axin level. Cell Commun Signal. 2020 Jan 31;18(1):16. doi: 10.1186/s12964-020-0513-5.
4 FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Res. 2003 Nov 1;63(21):7436-42.