Details of the Drug

General Information of Drug (ID: DMCUGNY)

• Drug Name: Tetomilast
• Synonyms: Tetomilast; 145739-56-6; 6-(2-(3,4-Diethoxyphenyl)thiazol-4-yl)picolinic acid; OPC-6535; UNII-S6RXB5KF56; S6RXB5KF56; 2-(3,4-Diethoxyphenyl)-4-(2-carboxy-6-pyridyl)thiazole; 2-Pyridinecarboxylicacid, 6-[2-(3,4-diethoxyphenyl)-4-thiazolyl]-; 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid; Tetomilast [INN]; 6-(2-(3,4-Diethoxyphenyl)-1,3-thiazol-4-yl)pyridine-2-carboxylic acid; OPC 6535; ACMC-1BW9F; AC1MHG07; SCHEMBL436663; GTPL9877; CHEMBL332750; CTK0H7037; OPC6535; DTXSID00163149

Indication

Disease Entry	ICD 11	Status	REF
Chronic obstructive pulmonary disease	CA22	Phase 2	[1]

• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C19H18N2O4S
  Canonical SMILES: CCOC1=C(C=C(C=C1)C2=NC(=CS2)C3=NC(=CC=C3)C(=O)O)OCC
  InChI: InChI=1S/C19H18N2O4S/c1-3-24-16-9-8-12(10-17(16)25-4-2)18-21-15(11-26-18)13-6-5-7-14(20-13)19(22)23/h5-11H,3-4H2,1-2H3,(H,22,23)
  InChIKey: XDBHURGONHZNJF-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 3025803
  ChEBI ID: CHEMBL332750
  CAS Number: 145739-56-6
  UNII: S6RXB5KF56
  DrugBank ID: DB05298
  TTD ID: D0T6IM
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

References

• [1] ClinicalTrials.gov (NCT00874497) Pilot Study of Tetomilast in Chronic Obstructive Pulmonary Disease (COPD) Associated With Emphysema. U.S. National Institutes of Health.