Details of the Drug

General Information of Drug (ID: DMCVU1T)

Drug Name
UNC0321
Synonyms UNC-0321; UNC 0321
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 515.7
Logarithm of the Partition Coefficient (xlogp) 2.9
Rotatable Bond Count (rotbonds) 11
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 10
Chemical Identifiers
Formula
C27H45N7O3
IUPAC Name
7-[2-[2-(dimethylamino)ethoxy]ethoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Canonical SMILES
CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OCCOCCN(C)C
InChI
InChI=1S/C27H45N7O3/c1-31(2)15-16-36-17-18-37-25-20-23-22(19-24(25)35-5)26(28-21-7-11-33(4)12-8-21)30-27(29-23)34-10-6-9-32(3)13-14-34/h19-21H,6-18H2,1-5H3,(H,28,29,30)
InChIKey
AULLUGALUBVBDD-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
46901937
ChEBI ID
CHEBI:94307
TTD ID
D0CX4W

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone-lysine N-methyltransferase EHMT2 (EHMT2) TTS6RZT EHMT2_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 149 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 6.2678 7.7691 4.516 0.7528
JM1 CTRP2 6.5061 8.8182 4.1914 1.5603
HuT 78 CTRP2 3.8041 12.6309 0.1737 22.1453
Hs 611.T CTRP2 5.1177 7.6552 3.7996 5.0926
Granta-519 CTRP2 5.28 6.9257 4.2921 2.7354
OPM-2 CTRP2 5.6882 8.5511 3.7943 4.1344
DB CTRP2 5.8872 9.717 3.3678 5.5763
EoL-1 CTRP2 5.946 9.066 3.7264 4.0227
SIG-M5 CTRP2 5.9618 8.3807 4.0648 2.8358
HL-60 CTRP2 5.9887 7.511 4.4808 1.1267
Ci-1 CTRP2 6.0511 7.1017 4.6847 0.3661
KO52 CTRP2 6.0611 7.9702 4.3168 1.6763
KMS-26 CTRP2 6.0729 11.6742 2.5427 8.6578
JJN-3 CTRP2 6.1554 8.7409 4.0196 2.5759
JeKo-1 CTRP2 6.2053 8.1326 4.3268 1.3792
KMS-21-BM CTRP2 6.2327 9.7326 3.6014 4.1184
KMS-28BM CTRP2 6.245 8.8508 4.0244 2.449
Daudi CTRP2 6.2534 10.3437 3.3221 5.2098
KMS-12-BM CTRP2 6.281 8.9515 4 2.4987
SKM-1 CTRP2; CTRP1 6.2833 7.7127 4.5602 0.6136
NU-DUL-1 CTRP2; CTRP1 6.2889 7.7914 4.5305 0.697
697 CTRP2 6.293 9.9448 3.5404 4.2784
NALM-6 CTRP2 6.2955 9.1598 3.9124 2.816
MC116 CTRP2 6.3092 7.1537 4.7709 0.0936
KMS-20 CTRP2 6.3347 8.4104 4.2761 1.4304
NU-DHL-1 CTRP2 6.3678 11.8042 2.6939 7.5774
MM1.S CTRP2 6.381 8.3962 4.3077 1.2791
MOLM-16 CTRP2; CTRP1 6.3923 8.4921 4.2849 1.4079
Kasumi-1 CTRP2 6.4037 8.1013 4.445 0.8177
EM-2 CTRP2 6.41 8.226 4.3959 0.9652
NCI-H929 CTRP2 6.4115 8.5007 4.2786 1.3497
MOLT-3 CTRP2 6.4157 7.3503 4.7412 0.1106
MOLM-13 CTRP2 6.4161 10.2959 3.455 4.4497
Mino CTRP2 6.4164 7.6338 4.6375 0.2979
KMM-1 CTRP2 6.4354 9.8342 3.6858 3.5176
CMK CTRP2 6.4377 7.629 4.6482 0.2664
RPMI-8402 CTRP2 6.4462 9.5037 3.8465 2.8858
L-540 CTRP2 6.4492 8.0295 4.4966 0.6354
SUP-M2 CTRP2 6.4712 7.5771 4.6809 0.1914
OCI-AML-3 CTRP2; CTRP1 6.4848 8.3964 4.3752 1.1009
OCI-Ly3 CTRP2 6.4869 7.83 4.5925 0.3674
SU-DHL-10 CTRP2 6.4911 7.4993 4.7167 0.1279
OCI-Ly10 CTRP2 6.5068 9.2393 4.004 2.2279
MV4-11 CTRP2 6.5192 8.3634 4.3932 0.8901
BL-70 CTRP2 6.5227 7.4389 4.7494 0.0847
THP-1 CTRP2; CTRP1 6.5293 8.8875 4.1866 1.6175
OCI-AML-5 CTRP2 6.5476 7.636 4.6893 0.155
NCO2 CTRP2 6.553 8.772 4.2369 1.3629
HEL 92.1.7 CTRP2 6.5645 10.4365 3.4855 4.4269
NB4 CTRP2 6.5736 7.7232 4.6678 0.1826
Kasumi-2 CTRP2 6.5808 9.1033 4.1072 1.7814
M-07e CTRP2 6.6137 12.6715 2.4463 8.1933
SEM CTRP2 6.6202 7.7977 4.659 0.1838
AML-193 CTRP2 6.6222 7.8558 4.6386 0.2186
KE-97 CTRP2 6.6368 8.5685 4.366 0.8866
Peer CTRP2 6.6495 8.2536 4.4989 0.5118
KMS-27 CTRP2 6.6588 11.395 3.0928 5.5542
BL-41 CTRP2 6.6611 7.6586 4.7233 0.0847
SU-DHL-5 CTRP1 6.6646 7.6327 4.7478 0.1623
HD-MY-Z CTRP2 6.6655 8.7571 4.3016 1.1369
RPMI-6666 CTRP2 6.6841 8.5395 4.4006 0.7541
TF-1 CTRP2 6.6955 8.0531 4.5951 0.2946
OCI-M1 CTRP2 6.7015 8.1896 4.5463 0.4013
Namalwa CTRP2 6.7129 8.4172 4.4629 0.5687
OCI-AML-2 CTRP2 6.7201 11.2748 3.1906 5.0848
K-562 CTRP2 6.7836 8.4937 4.4644 0.5648
GA-10 CTRP2 6.7844 8.2279 4.5662 0.2992
Raji CTRP2 6.7997 8.1624 4.5965 0.2369
DEL CTRP2 6.8042 7.8708 4.7015 0.085
AMO1 CTRP2 6.8062 7.9753 4.666 0.127
HEL CTRP2 6.8173 8.1612 4.6038 0.2186
MOLM-6 CTRP2 6.8235 8.6787 4.4093 0.6455
A3/Kawakami CTRP2 6.8285 7.8199 4.7274 0.0571
L-363 CTRP2 6.8311 7.8644 4.7132 0.0693
U-937 CTRP2; CTRP1 6.8346 8.4811 4.5052 0.4458
ME1 CTRP2 6.839 8.5163 4.4797 0.4629
RL CTRP2 6.8494 8.2422 4.5869 0.238
Karpas-299 CTRP2 6.8496 8.3834 4.5347 0.3377
SU-DHL-1 CTRP2 6.8593 8.0467 4.6605 0.1231
MOLT-13 CTRP2 6.9088 8.4762 4.5243 0.336
GDM-1 CTRP2; CTRP1 6.9138 8.7159 4.4487 0.541
MOTN-1 CTRP2 6.9196 9.6007 4.074 1.5835
KMS-34 CTRP2 6.9256 8.3254 4.5864 0.2159
Reh CTRP2 6.9303 8.2147 4.6277 0.1516
HT CTRP2 6.9436 8.3153 4.5969 0.194
KYO-1 CTRP2 6.9453 8.3283 4.5929 0.1998
SU-DHL-8 CTRP2 6.9474 8.5093 4.5276 0.315
SET-2 CTRP2 6.9615 8.1797 4.6514 0.1146
SUP-B15 CTRP2 6.9957 8.4475 4.5694 0.2238
Jurkat CTRP2 7.0088 8.4437 4.5758 0.2097
EJM CTRP2 7.0177 9.0037 4.3683 0.643
RS4;11 CTRP2 7.0208 8.7202 4.4789 0.3853
CML-T1 CTRP2 7.0382 8.5904 4.5341 0.2718
NOMO-1 CTRP2; CTRP1 7.0514 13.7345 2.2483 8.3934
Pfeiffer CTRP2 7.0615 8.4253 4.6022 0.1574
PL21 CTRP2; CTRP1 7.0754 8.979 4.4171 0.5367
KE-37 CTRP2 7.0936 8.1325 4.7136 0.041
HPB-ALL CTRP2 7.1222 9.0563 4.3936 0.5289
ST486 CTRP2 7.1319 8.6036 4.5654 0.1935
SU-DHL-4 CTRP2; CTRP1 7.1372 8.3494 4.6702 0.0839
KM-H2 CTRP2 7.1399 9.6295 4.1732 1.1029
WSU-DLCL2 CTRP2; CTRP1 7.1436 8.5798 4.5925 0.1756
RCH-ACV CTRP2 7.1467 8.7878 4.5046 0.2896
EB1 CTRP2 7.1522 8.765 4.5151 0.2693
MOLP-8 CTRP2 7.1531 8.89 4.4695 0.3535
U266B1 CTRP2 7.1716 13.8917 2.2434 8.1707
DND-41 CTRP2 7.1977 8.6299 4.5807 0.1567
JVM-3 CTRP2 7.1984 8.9467 4.4668 0.3424
SR CTRP2 7.2077 8.6602 4.5738 0.1639
P12-Ichikawa CTRP2 7.2171 8.643 4.5833 0.1493
Ku812 CTRP2 7.2294 9.1033 4.421 0.4223
OCI-Ly19 CTRP2 7.2531 9.1324 4.4198 0.4153
KCL-22 CTRP2 7.2578 8.9207 4.4998 0.2637
HuNS1 CTRP2 7.2607 8.8816 4.515 0.2548
Karpas-620 CTRP2 7.2742 8.5001 4.6526 0.0677
PF-382 CTRP2 7.2767 8.8863 4.5194 0.2264
SUP-T11 CTRP2 7.296 8.8154 4.5519 0.1742
KMS-18 CTRP2 7.3199 9.8549 4.1671 1.0013
P31/FUJ CTRP2 7.3203 8.4233 4.6937 0.0357
A4/Fukuda CTRP2 7.3549 14.0248 2.3031 8.2052
F-36P CTRP2 7.3783 12.0631 3.2366 4.0963
Ki-JK CTRP2 7.3896 9.463 4.3518 0.503
CA46 CTRP2 7.4412 9.5098 4.3556 0.4734
REC-1 CTRP2 7.4769 9.1943 4.4854 0.2268
MOLT-16 CTRP2 7.4805 8.7841 4.6283 0.0646
JURL-MK1 CTRP2 7.487 8.7774 4.6327 0.0607
P3HR-1 CTRP2 7.4883 9.0123 4.5534 0.1344
KMS-11 CTRP2 7.5078 9.3366 4.4462 0.2802
EHEB CTRP2 7.5146 9.2879 4.4663 0.2462
Mono-Mac-1 CTRP2 7.528 15.4783 1.7241 9.6376
HH [Human lymphoma] CTRP2 7.55 9.4289 4.4292 0.2963
KHM-1B CTRP2 7.5735 9.0257 4.5791 0.0949
HDLM-2 CTRP2 7.6384 9.5425 4.4223 0.2824
MJ CTRP2 7.6705 10.4861 4.0762 1.0344
LAMA-84 CTRP2 7.7048 9.3769 4.5055 0.1514
Toledo CTRP2 7.7575 9.7926 4.378 0.3212
Ri-1 CTRP2 7.8239 10.1355 4.2784 0.4822
MOLP-2 CTRP2 7.8307 9.7628 4.4166 0.2414
JVM-2 CTRP2 7.8369 9.9098 4.3663 0.3176
MHH-CALL-4 CTRP2 7.8539 9.4994 4.5166 0.1158
MHH-CALL-3 CTRP2 7.8809 10.0845 4.32 0.3837
Karpas-422 CTRP2 7.8927 14.3839 2.4811 6.3112
BV-173 CTRP2 7.9281 9.4749 4.5506 0.0774
TALL-1 [Human adult T-ALL] CTRP2 7.9321 9.9157 4.4004 0.2406
RPMI-8226 CTRP2; CTRP1 7.9617 9.3158 4.6289 0.0368
SUP-HD1 CTRP2 8.0357 10.1215 4.3663 0.2651
LP-1 CTRP2 9.3149 22.5557 -0.4587 14.4669
SUP-T1 CTRP2 9.4197 25.0458 -1.5864 17.4682
L-428 CTRP2 12.17 33.7714 -3.9024 19.3198
⏷ Show the Full List of 149 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 6.391 9.4483 3.8379 2.985
TE15 CTRP2 7.6265 11.0686 3.8147 1.8361
TE-6 CTRP2 5.0215 7.2931 2.2622 1.1028
COLO 680N CTRP2 6.124 8.0189 4.3314 1.4449
KYSE-70 CTRP2 6.3908 9.165 3.9688 2.4882
TE-4 CTRP2 6.5519 8.4108 4.3896 0.877
OE21 CTRP2 6.6513 9.2416 4.0853 1.9172
TE-5 CTRP2 6.7749 9.0625 4.2284 1.2911
OE19 CTRP2 6.818 8.1714 4.6004 0.2403
TE-11 CTRP2 6.8478 9.418 4.1147 1.6191
KYSE-520 CTRP2 6.9052 9.8813 3.9441 2.1816
KYSE-450 CTRP2 7.0104 8.4249 4.5832 0.2118
EC-GI-10 CTRP2 7.0897 8.8646 4.453 0.441
KYSE-510 CTRP2 7.1386 8.5536 4.5857 0.1629
OE33 CTRP2 7.1609 8.9118 4.4646 0.386
KYSE-30 CTRP2 7.1805 8.7364 4.5364 0.2255
TE-9 CTRP2 7.2353 9.188 4.3914 0.483
KYSE-150 CTRP2 7.2933 8.617 4.6197 0.0949
KYSE-410 CTRP2 7.4744 9.3366 4.4332 0.3122
KYSE-180 CTRP2 7.5935 13.3951 2.7539 5.6536
TE-10 CTRP2 7.6313 9.7009 4.3618 0.3902
KYSE-140 CTRP2 7.7764 16.031 1.6273 9.6455
TE-1 CTRP2 8.0964 9.744 4.5183 0.0846
TE-14 CTRP2 10.9151 25.7267 -0.9092 13.7193
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 7.3467 8.9569 4.5207 0.2213
TCC-Pan2 CTRP2 6.5523 8.4608 4.369 0.9392
SNU-213 CTRP2 6.5679 8.3638 4.4168 0.7849
Panc 08.13 CTRP2 6.6213 9.1835 4.0943 1.7871
SUIT-2 CTRP2 6.6541 8.6088 4.3577 0.8989
PSN1 CTRP2 6.7062 9.2856 4.0962 1.7
SU.86.86 CTRP2 6.7215 8.2461 4.5331 0.395
Hs 766T CTRP2 6.7431 11.4019 3.1454 5.2318
KP-4 CTRP2 6.8237 11.8943 2.9646 5.8345
MIA PaCa-2 CTRP2 6.8245 8.8016 4.3605 0.832
Panc 10.05 CTRP2 6.8573 10.2537 3.7505 2.7767
PaTu 8988t CTRP2 6.8623 8.0371 4.6649 0.1169
PaTu 8902 CTRP2 6.9241 8.128 4.6558 0.1163
HuP-T3 CTRP2 6.9446 11.1884 3.3746 4.3755
PK-45H CTRP2 7.0826 8.9235 4.4277 0.5033
DAN-G CTRP2 7.1034 8.7701 4.4939 0.3241
Capan-1 CTRP2 7.1493 8.9707 4.4377 0.4495
Panc 05.04 CTRP2 7.1579 8.6652 4.5533 0.2052
PK-59 CTRP2 7.177 8.8541 4.4923 0.302
L3.3 CTRP2 7.191 8.2915 4.6938 0.0456
SNU-410 CTRP2 7.2647 9.0799 4.4441 0.3623
HPAC CTRP2 7.2977 8.7912 4.561 0.1616
YAPC CTRP2 7.3189 8.3859 4.7055 0.0298
BxPC-3 CTRP2 7.351 9.7556 4.2213 0.8362
Panc 04.03 CTRP2 7.3638 9.0339 4.4998 0.2507
Capan-2 CTRP2 7.3906 9.8584 4.1984 0.8734
HPAF-II CTRP2 7.4051 9.122 4.484 0.2477
Panc 03.27 CTRP2 7.4161 8.8338 4.589 0.1075
HuP-T4 CTRP2 7.4245 9.3632 4.4036 0.3833
KP-2 CTRP2 7.4478 8.7787 4.6188 0.0756
KP-3 CTRP2 7.5584 9.7503 4.3136 0.5142
CFPAC-1 CTRP2 7.6049 9.0571 4.5794 0.0905
PaTu 8988s CTRP2 7.6694 9.2277 4.5441 0.1234
AsPC-1 CTRP2 7.7816 9.6192 4.449 0.2073
SW1990 CTRP2 7.9115 9.5858 4.5074 0.1165
Panc 02.03 CTRP2 7.9625 9.2231 4.645 0.0236
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 7.8679 17.9195 0.781 12.5369
Hs 940.T CTRP2 5.5698 8.6719 3.6477 4.9313
SK-MEL-28 CTRP2; CTRP1 5.8287 6.5549 4.8141 0.2044
A2058 CTRP2 6.1904 7.1905 4.7109 0.2351
Hs 839.T CTRP2 6.2862 7.8539 4.4898 0.7684
SK-MEL-2 CTRP2 6.3511 7.2711 4.745 0.1204
UACC-62 CTRP2 6.3748 8.1834 4.3959 1.0644
SK-MEL-3 CTRP2 6.3802 9.3668 3.8691 2.8789
CJM [Human melanoma] CTRP2 6.4357 10.4363 3.4012 4.6367
Hs 688(A).T CTRP2 6.4441 10.1857 3.5257 4.1328
SK-MEL-31 CTRP2 6.4526 7.7504 4.6084 0.3469
RPMI-7951 CTRP2 6.5092 8.3416 4.3973 0.885
Hs 934.T CTRP2 6.5307 8.1462 4.4876 0.6093
WT2-iPS CTRP2 6.6418 7.9365 4.6167 0.2526
A-375 CTRP2; CTRP1 6.6546 8.5869 4.3804 0.8836
WM115 CTRP2 6.6817 9.1762 4.1306 1.7196
WM266-4 CTRP2 6.7132 7.7894 4.6969 0.1139
Mel Ho CTRP2 6.7257 8.6179 4.3884 0.7616
IGR-39 CTRP2 6.7561 8.2083 4.5619 0.3186
WM1799 CTRP2 6.7811 8.7582 4.3577 0.8124
RVH-421 CTRP2 6.7928 8.2795 4.5503 0.328
IGR-37 CTRP2 6.812 8.283 4.5569 0.3074
SK-MEL-30 CTRP2 6.8278 7.9694 4.6759 0.1101
Hs 294T CTRP2 6.8398 8.2629 4.5755 0.2617
A101D CTRP2 6.8473 8.0147 4.6673 0.117
SK-MEL-1 CTRP2; CTRP1 6.8866 8.2717 4.6048 0.2249
MeWo CTRP2 6.8905 9.7687 3.9855 2.0435
Hs 852.T CTRP2 6.9106 8.4353 4.5402 0.3039
K029AX CTRP2 6.9183 8.3431 4.5771 0.2504
WM88 CTRP2 6.9458 9.5974 4.0891 1.5118
Hs 944.T CTRP2 6.9498 8.7182 4.4497 0.4803
LOX-IMVI CTRP2 7.0059 8.3218 4.618 0.1481
HMCB CTRP2 7.0145 8.0939 4.6994 0.0588
COLO 829 CTRP2 7.0418 8.9264 4.4091 0.5312
Hs 936.T CTRP2 7.0479 8.3782 4.6138 0.1448
IGR-1 CTRP2 7.0697 8.6484 4.5252 0.2775
WM793 CTRP2 7.0827 8.3373 4.6406 0.1056
IPC-298 CTRP2 7.1186 8.1973 4.7005 0.0475
UACC-257 CTRP2 7.1455 8.6171 4.5658 0.2032
SK-MEL-5 CTRP2; CTRP1 7.1746 8.238 4.7204 0.0404
MDA-MB-435S CTRP2 7.176 8.3894 4.6558 0.0767
Hs 895.T CTRP2 7.1893 8.4254 4.6483 0.0877
COLO 741 CTRP2 7.2788 9.7397 4.1944 0.9516
HT-144 CTRP2 7.3982 8.7257 4.6195 0.081
COLO 792 CTRP2 7.4113 9.1735 4.4678 0.2723
Mel JuSo CTRP2 7.4549 8.9447 4.5648 0.1273
SK-MEL-24 CTRP2 7.5211 8.8395 4.6237 0.0685
G-361 CTRP2 7.6002 9.0739 4.5721 0.0978
WM983B CTRP2 7.7031 9.5219 4.4541 0.2178
COLO 800 CTRP2 7.7848 9.3053 4.5581 0.0933
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 5.8796 10.619 2.9188 7.437
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-YN CTRP2 5.4636 7.1707 4.3071 2.3774
SK-N-DZ CTRP2 5.9236 7.6302 4.39 1.5491
NB1 CTRP2 6.3844 7.7153 4.5923 0.4192
NH-6 CTRP2 6.3929 7.9561 4.4997 0.7109
SK-N-AS CTRP2 6.4059 9.4803 3.8323 3.2018
Kelly CTRP2 6.4867 12.7155 2.3343 8.8342
MHH-NB-11 CTRP2 6.8075 9.6099 4.0095 1.9028
CHP-212 CTRP2 6.9143 8.5658 4.4928 0.4282
IMR-32 CTRP2 6.9676 8.0571 4.6956 0.0724
SK-N-FI CTRP2 7.0182 8.7263 4.4754 0.4217
KP-N-SI9s CTRP2 7.0382 8.8726 4.4282 0.4885
SK-N-SH CTRP2 7.4368 9.5553 4.3366 0.5159
SK-N-BE(2) CTRP2 7.862 9.7435 4.4351 0.2086
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-245 CTRP2 5.9921 9.6139 3.4932 4.9018
HuCC-T1 CTRP2 6.034 8.4577 4.0751 2.5132
SNU-869 CTRP2 6.6723 8.4851 4.4171 0.7155
HuH-28 CTRP2 7.1423 8.5162 4.6002 0.1429
SNU-478 CTRP2 7.2493 8.9022 4.5032 0.2604
SNU-308 CTRP2 7.2606 8.7526 4.5608 0.1698
SNU-1079 CTRP2 7.4459 9.3936 4.4009 0.3807
SNU-1196 CTRP2 7.5304 8.8603 4.6199 0.0658
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 888.T CTRP2 3.1584 12.2997 -0.2541 25.0428
CADO-ES1 CTRP2 5.6061 7.1624 4.409 1.7615
TC71 CTRP2 6.2906 8.1337 4.3731 1.1402
Hs 822.T CTRP2 6.485 14.4425 1.4852 12.1441
SK-N-MC CTRP2 6.5279 7.4454 4.749 0.0786
U2OS CTRP2 6.5889 9.5372 3.9173 2.4566
MG-63 CTRP2 6.7275 11.0114 3.3199 4.5687
SJSA-1 CTRP2 6.7969 10.4629 3.619 3.3336
G-292 clone A141B1 CTRP2 7.0378 10.0487 3.9433 1.9155
SW1353 CTRP2 7.1993 8.9835 4.4534 0.368
A-673 CTRP2 7.313 8.6053 4.6306 0.0877
HOS CTRP2 7.4021 8.6512 4.6459 0.0594
CAL-78 CTRP2 7.4884 9.1041 4.5216 0.1733
SK-ES-1 CTRP2 7.6617 16.2402 1.449 10.4623
SaOS-2 CTRP2 7.8224 9.4355 4.5272 0.1099
MHH-ES-1 CTRP2 10.4438 22.4281 0.3342 10.6305
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BT-474 CTRP2 4.664 12.0886 1.2005 16.6119
CAL-148 CTRP2 5.6857 7.8247 4.1456 2.705
HMC-1-8 CTRP2 6.0894 9.1407 3.788 3.5719
KPL-1 CTRP2 6.2447 7.0406 4.7868 0.0862
HDQ-P1 CTRP2 6.2584 7.9148 4.4501 0.915
Hs 578Bst CTRP2 6.3812 7.5831 4.642 0.3034
MDA-MB-468 CTRP2 6.4964 8.5178 4.3164 1.1497
ZR-75-1 CTRP2 6.5732 8.9901 4.1528 1.63
DU4475 CTRP2 6.6909 8.1142 4.5704 0.3271
CAL-85-1 CTRP2 6.8571 16.1307 0.9298 13.5779
HCC2218 CTRP2 6.8639 9.269 4.1865 1.2669
MDA-MB-157 CTRP2 6.9075 8.9985 4.3198 0.8373
AU565 CTRP2 6.9133 12.8216 2.5815 7.2187
UACC-812 CTRP2 6.9547 8.7484 4.4402 0.5358
MDA-MB-361 CTRP2 7.0036 9.0965 4.3251 0.7636
CAL-120 CTRP2 7.0507 8.3034 4.6408 0.1109
Hs 578T CTRP2 7.0903 8.7176 4.508 0.3021
HCC1954 CTRP2 7.1276 9.1516 4.3591 0.6082
T-47D CTRP2 7.1508 11.7136 3.259 4.2771
HCC1143 CTRP2 7.176 10.688 3.7386 2.4905
HCC1500 CTRP2 7.1821 8.8972 4.4785 0.3258
HCC1428 CTRP2 7.1885 8.733 4.5407 0.2321
HCC38 CTRP2 7.2508 9.2225 4.3848 0.5257
JIMT-1 CTRP2 7.2535 8.7398 4.5627 0.1688
MCF-7 CTRP2 7.3009 9.1376 4.4373 0.3624
BT-549 CTRP2 7.3216 9.1327 4.4474 0.3601
HCC1806 CTRP2 7.3256 8.9904 4.5008 0.2427
CAL-51 CTRP2 7.3321 8.829 4.5604 0.1553
ZR-75-30 CTRP2 7.3387 9.1089 4.4629 0.3025
MDA-MB-231 CTRP2 7.3482 9.4875 4.3249 0.5818
BT-20 CTRP2 7.3625 9.1225 4.4673 0.308
CAMA-1 CTRP2 7.4386 8.8146 4.6035 0.0902
HCC1937 CTRP2 7.4808 9.7589 4.2774 0.6293
HCC1395 CTRP2 7.5676 9.3957 4.4479 0.2609
MDA-MB-453 CTRP2 7.606 9.488 4.4294 0.2798
HCC202 CTRP2 7.8483 9.743 4.4301 0.2338
BT 330 CTRP2 5.6606 7.2102 4.4219 1.639
BT 504 CTRP2 5.7405 8.0522 4.0737 2.9162
BT 286 CTRP2 6.0349 9.0282 3.8052 3.5785
BT 440 CTRP2 6.1183 7.8383 4.4083 1.179
BT 359 CTRP2 6.1979 11.0788 2.9262 6.8986
BT 482 CTRP2 6.2713 7.961 4.4371 0.946
BT 498 CTRP2 6.3271 10.3765 3.3567 4.9649
BT 444 CTRP2 6.4064 7.5919 4.6492 0.277
BT 239 CTRP2 6.4445 7.8074 4.5828 0.4113
BT 179 CTRP2 6.4561 8.299 4.3885 1.0201
BT 340 CTRP2 6.4997 9.6413 3.8159 2.9383
BT 328 CTRP2 6.504 7.9983 4.5343 0.5011
BT 112 CTRP2 6.5093 8.0148 4.5302 0.545
BT 145 CTRP2 6.519 8.1199 4.4927 0.6455
BT 320 CTRP2 6.5855 7.4903 4.7541 0.0643
BT 428 CTRP2 6.648 8.4717 4.4111 0.748
BT 139 CTRP2 6.6543 7.9127 4.6305 0.2228
BT 416 CTRP2 6.6654 7.9553 4.6192 0.2397
BT164 CTRP2 6.7103 7.925 4.6478 0.1893
BT 333 CTRP2 6.7186 9.2755 4.1073 1.6505
BT 216 CTRP2 6.7436 8.4126 4.4784 0.5133
BT 422 CTRP2 6.7582 8.0908 4.6063 0.2326
BT 172 CTRP2 6.7793 11.7785 2.9903 5.7941
BT 228 CTRP2 6.7977 10.1847 3.7467 2.8562
BT 159 CTRP2 6.8155 7.9357 4.6832 0.1037
BT 232 CTRP2 6.8391 11.8801 2.9817 5.7464
BT 224 CTRP2 6.9453 8.2707 4.6135 0.1805
BT 248 CTRP2 7.1216 9.4757 4.2273 0.9596
BT 231 CTRP2 7.2284 9.64 4.2111 0.9369
BT147 CTRP2 7.259 8.7168 4.5728 0.1542
BT 245 CTRP2 7.9139 9.2623 4.6162 0.0379
BT 187 CTRP2 8.0953 14.099 2.7362 5.1311
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.0127 8.1301 4.6866 0.0699
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KNS-42 CTRP2 5.3103 6.5667 4.4919 1.9894
CCF-STTG1 CTRP2 5.6302 8.8104 3.6245 5.2801
SNU-489 CTRP2 5.6971 7.9558 4.0902 2.9123
SNU-466 CTRP2 5.8887 7.3683 4.4878 1.1265
U-118MG CTRP2 6.0361 8.327 4.1376 2.2689
NMC-G1 CTRP2 6.0645 7.5042 4.5246 0.835
CAS-1 CTRP2 6.1269 7.5431 4.5402 0.7341
YKG-1 CTRP2 6.1544 7.5745 4.5408 0.7617
A-172 CTRP2 6.1787 8.3119 4.2312 1.751
SNU-626 CTRP2 6.1905 8.6406 4.0879 2.2723
SNU-1105 CTRP2 6.2738 7.6483 4.5684 0.5466
SNU-201 CTRP2 6.2763 10.1063 3.4519 4.6554
KNS-81 CTRP2 6.308 7.3573 4.6967 0.2181
KG-1-C CTRP2 6.3584 11.0383 3.0593 6.1168
U-251MG CTRP2 6.391 8.0419 4.4635 0.7714
SF295 CTRP2 6.3922 8.9239 4.0795 2.0754
SW1783 CTRP2 6.416 10.2637 3.4703 4.3893
LN-229 CTRP2; CTRP1 6.474 9.6979 3.7859 3.1536
KNS-60 CTRP2 6.4855 7.7363 4.6276 0.2903
Hs 683 CTRP2 6.5235 7.6213 4.6853 0.1801
LN-18 CTRP2 6.5416 7.6226 4.6918 0.1526
YH-13 CTRP2 6.6833 8.1054 4.5705 0.3298
Becker CTRP2 6.7608 10.3392 3.6539 3.2442
TM-31 CTRP2 6.7717 7.8375 4.7013 0.0906
SNU-738 CTRP2 6.7814 8.1671 4.5875 0.2593
U-87MG ATCC CTRP2 6.806 7.9561 4.6726 0.1184
DK-MG CTRP2 6.8149 8.0684 4.6363 0.1788
T98G CTRP2 6.8398 8.4479 4.5063 0.4024
M059K CTRP2 6.9102 8.0051 4.6931 0.0776
GaMG CTRP2 7.0244 8.8114 4.4458 0.4552
SNB-75 CTRP2 7.0796 14.9722 1.6574 10.5488
GMS-10 CTRP2 7.1044 8.5318 4.5806 0.1779
D283 Med CTRP2 7.1745 8.5185 4.6111 0.1321
SW1088 CTRP2 7.1749 9.1009 4.3991 0.4925
GB-1 CTRP2 7.2133 8.8474 4.5091 0.2611
Daoy CTRP2 7.3472 8.7638 4.5885 0.1191
42-MG-BA CTRP2 7.5652 9.228 4.5064 0.1771
GOS-3 CTRP2 7.5742 8.9247 4.6134 0.0663
SF539 CTRP2 7.6069 8.9776 4.6069 0.0678
DBTRG-05MG CTRP2 7.6167 9.2303 4.5244 0.1452
8-MG-BA CTRP2 7.6385 9.1238 4.5686 0.096
SF126 CTRP2 7.6992 9.0112 4.627 0.0464
ONS-76 CTRP2 7.7553 9.0801 4.6231 0.0446
KALS-1 CTRP2 7.981 9.7744 4.4675 0.1469
SF268 CTRP2 11.2296 32.6139 -3.9881 20.6008
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-251 CTRP2 6.3712 7.9779 4.4802 0.7354
HEC-1-B CTRP2 6.5854 8.458 4.3865 0.8621
EN CTRP2 6.59 7.9192 4.602 0.3015
AN3-CA CTRP2 6.5931 8.9386 4.1862 1.4976
MFE-319 CTRP2 6.9011 8.1876 4.6264 0.1603
HEC-6 CTRP2 6.9055 8.3196 4.5807 0.2315
HEC-151 CTRP2 6.988 8.4255 4.5744 0.2179
KLE CTRP2 6.9934 9.442 4.179 1.1908
JHUEM-1 CTRP2 7.0623 8.2795 4.6532 0.1022
MFE-296 CTRP2 7.0809 12.3151 2.9339 5.6122
HEC-265 CTRP2 7.0877 8.1567 4.7035 0.0482
HEC-59 CTRP2 7.3252 8.5007 4.6698 0.0498
JHUEM-7 CTRP2 7.3332 8.6494 4.6226 0.0927
EFE-184 CTRP2 7.3716 8.9976 4.5157 0.2079
HEC-108 CTRP2 7.4315 8.5905 4.6759 0.0379
JHUEM-2 CTRP2; CTRP1 7.4468 12.8691 2.9191 5.2759
JHUEM-3 CTRP2 7.5003 9.9148 4.2255 0.7972
ESS-1 CTRP2 7.5069 8.8609 4.6116 0.0748
RL95-2 CTRP2 7.5981 9.5732 4.3955 0.3397
HEC-1-A CTRP2 7.7362 9.8011 4.3666 0.3472
HEC-50B CTRP2 7.7801 9.1689 4.6021 0.0552
Ishikawa (Heraklio) 02 ER- CTRP2 6.6908 7.6557 4.7349 0.068
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-909 CTRP2 5.4819 7.4118 4.2026 2.7781
SNU-1272 CTRP2 6.1378 7.8003 4.4357 1.0668
TUHR14TKB CTRP2 6.2411 14.6899 1.1791 13.7033
TUHR10TKB CTRP2 6.3525 7.425 4.6896 0.2157
KMRC-3 CTRP2 6.4406 9.5643 3.8149 3.013
RCC10RGB CTRP2 6.6427 8.2769 4.4867 0.5465
KMRC-2 CTRP2 6.6805 9.6824 3.9053 2.573
CAL-54 CTRP2 6.6869 9.032 4.1958 1.4811
VMRC-RCW CTRP2 6.8133 9.1383 4.2159 1.214
TUHR4TKB CTRP2 6.8364 8.7258 4.3965 0.6718
Caki-2 CTRP2 6.8855 8.3359 4.5669 0.2624
A-498 CTRP2 6.9426 8.1742 4.6465 0.1243
Caki-1 CTRP2 7.0563 8.775 4.4729 0.3836
VMRC-RCZ CTRP2 7.108 8.4259 4.6191 0.126
OS-RC-2 CTRP2 7.1902 8.9176 4.4742 0.3311
KMRC-20 CTRP2 7.2447 9.006 4.4634 0.3325
769-P CTRP2 7.5303 9.2048 4.5017 0.1909
786-O CTRP2 7.547 9.0594 4.5583 0.1279
KMRC-1 CTRP2 7.7009 9.0361 4.6193 0.0508
ACHN CTRP2 7.926 9.5691 4.5182 0.1046
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW948 CTRP2 0.5731 6.2522 -5.0469 7.786
CL-34 CTRP1 5.8856 9.5053 3.4813 10.9384
SNU-61 CTRP2 5.8945 8.413 4.005 2.9748
HT115 CTRP2; CTRP1 6.1048 7.3851 4.6085 0.5961
SK-CO-1 CTRP2 6.1729 8.2416 4.2596 1.6534
SNU-C1 CTRP2 6.2289 10.1099 3.4179 4.859
CW-2 CTRP2 6.3042 8.5501 4.1968 1.7422
COLO201 CTRP2 6.3445 7.9822 4.4653 0.7997
LS180 CTRP2 6.3526 9.4945 3.7922 3.2092
DLD-1 CTRP2 6.4594 7.5747 4.6772 0.202
NCI-H716 CTRP2 6.4933 8.5768 4.2894 1.3292
MDST8 CTRP2; CTRP1 6.5101 7.945 4.5718 0.4472
HCC-56 CTRP2 6.5928 7.5768 4.727 0.0925
LS411N CTRP2 6.6108 8.4368 4.4075 0.7827
SNU-1040 CTRP1 6.6209 7.8082 4.6695 0.4172
HCT 8 CTRP2; CTRP1 6.6316 7.7093 4.7091 0.1296
SNU-C4 CTRP2 6.6431 7.9494 4.6124 0.2604
COLO205 CTRP2 6.6697 7.8408 4.6625 0.1644
RKO CTRP2; CTRP1 6.685 8.4403 4.4546 0.6527
HT-29 CTRP2; CTRP1 6.7613 8.1588 4.5965 0.2817
NCI-H508 CTRP2; CTRP1 6.7714 8.3976 4.5102 0.4644
RCM-1 [Human ESC] CTRP2; CTRP1 6.8148 8.5327 4.4766 0.5608
CCK-81 CTRP2 6.8225 8.9583 4.2956 0.9642
SW480 CTRP1 6.8769 9.2956 4.1951 2.7537
LS1034 CTRP2 6.9066 8.3299 4.5774 0.2538
OUMS-23 CTRP2 6.9286 8.0468 4.6854 0.0826
SNU-503 CTRP2 6.9491 8.7406 4.4407 0.5014
LS513 CTRP2 6.9742 8.2551 4.6298 0.1392
HT-55 CTRP2; CTRP1 6.978 8.409 4.5906 0.2218
SW48 CTRP2 7.0099 8.6925 4.4848 0.3774
SW1116 CTRP2 7.0188 9.2629 4.2651 1.0638
SNU-C5 CTRP2 7.1017 9.9048 4.0389 1.545
HCT 15 CTRP2 7.1099 8.902 4.4473 0.4452
SNU-1033 CTRP2 7.154 11.1359 3.5253 3.2796
SW1417 CTRP2 7.2194 9.9487 4.08 1.3247
COLO 678 CTRP2; CTRP1 7.2337 9.2378 4.3856 0.5351
LoVo CTRP2; CTRP1 7.2541 9.5639 4.267 0.8173
GP2d CTRP2 7.2733 9.0368 4.4635 0.3458
HCT 116 CTRP2; CTRP1 7.2827 8.5897 4.6395 0.0931
KM12 CTRP2 7.3815 8.8419 4.5739 0.1296
CL-11 CTRP2 7.4086 9.1919 4.4601 0.286
LS123 CTRP2; CTRP1 7.4228 9.4642 4.3791 0.4674
COLO 320 CTRP2 7.4764 10.2719 4.0718 1.1689
T84 CTRP2 7.4894 10.2092 4.1034 1.0712
SNU-407 CTRP2 7.531 9.4049 4.4305 0.2997
CL-40 CTRP1 7.5601 9.2025 4.5277 0.3696
NCI-H747 CTRP2 7.6391 15.1832 1.9402 8.6724
SW620 CTRP2; CTRP1 7.7632 9.4048 4.5311 0.1314
SNU-81 CTRP2 7.7918 20.7656 -0.6607 17.2726
C2BBe1 CTRP2 7.9247 16.2354 1.629 10.0364
SNU-C2A CTRP2 8.521 17.8943 1.2345 10.0452
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-761 CTRP2 4.6794 7.4555 2.014 2.3657
SNU-878 CTRP2 5.3164 7.3563 4.1065 3.4474
JHH-6 CTRP2 6.0185 6.798 4.7873 0.1471
SK-HEP-1 CTRP2 6.6751 8.1217 4.5609 0.3539
JHH-1 CTRP2 6.7128 7.8599 4.6719 0.1395
SNU-182 CTRP2 6.7238 10.0795 3.7506 2.9244
Hep 3B2.1-7 CTRP2 6.9276 8.1355 4.6545 0.1173
Li-7 CTRP2 6.9362 10.0474 3.8881 2.2016
Hep-G2 CTRP2 7.0936 8.4798 4.595 0.1602
SNU-475 CTRP2 7.1843 8.3012 4.6883 0.0499
JHH-2 CTRP2 7.1995 8.6941 4.5587 0.1868
HLF CTRP2 7.2181 8.372 4.6762 0.0553
HuH-1 CTRP2 7.3301 8.6138 4.6336 0.077
SNU-886 CTRP2 7.3445 8.9713 4.5148 0.2159
PLC/PRF/5 CTRP2 7.4945 8.7891 4.6314 0.0609
SNU-423 CTRP2 7.638 9.4477 4.456 0.2305
JHH-5 CTRP2 7.6705 9.5218 4.4419 0.2607
SNU-398 CTRP2 7.8749 10.0437 4.3326 0.3635
JHH-4 CTRP2 8.032 9.8504 4.4596 0.1472
SNU-387 CTRP2 8.0958 9.6569 4.5471 0.0641
SNU-449 CTRP2 8.2927 9.9756 4.508 0.0781
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 146 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LC-1F CTRP2 0.9054 9.9594 -6.5389 15.3968
NCI-H2444 CTRP2 4.5622 5.9957 2.5694 0.4728
COR-L279 CTRP2 5.7308 8.5075 3.8462 3.8558
COR-L88 CTRP2 5.8183 8.1392 4.0847 2.7618
NCI-H2085 CTRP2 5.8186 9.4669 3.4405 5.3859
NCI-H889 CTRP2 5.8943 7.9751 4.2123 2.1571
NCI-H2106 CTRP2 5.9032 16.2876 0.1215 18.0158
NCI-H1092 CTRP2 5.9402 7.793 4.3254 1.7871
Sq-1 CTRP2 6.0623 8.754 3.9538 2.9515
LK2 CTRP2 6.0747 6.9768 4.7435 0.229
NCI-H1734 CTRP2 6.1085 8.3692 4.1629 2.085
MOR/CPR CTRP2 6.1243 7.0091 4.7517 0.1776
BEN CTRP2 6.1494 7.2916 4.6539 0.3905
COLO 668 CTRP2 6.204 8.8307 4.0083 2.7426
RERF-LC-Ad1 CTRP2 6.2061 12.9758 2.0003 10.6132
NCI-H1105 CTRP2 6.281 7.8945 4.4702 0.8331
NCI-H1694 CTRP2 6.2846 9.5185 3.7373 3.5108
NCI-H1975 CTRP2 6.2995 10.3566 3.3475 5.0413
NCI-H2087 CTRP2 6.4256 10.2119 3.5011 4.2543
NCI-H1581 CTRP2 6.4575 11.2968 3.0031 6.1975
Lu-99 CTRP2 6.4578 9.8782 3.6794 3.5141
HCC95 CTRP2 6.4889 8.0943 4.489 0.6313
IA-LM CTRP2 6.5338 7.9719 4.5579 0.4569
SBC-5 CTRP2 6.5645 7.4755 4.7517 0.0698
NCI-H2029 CTRP2 6.5748 8.2507 4.4661 0.6868
NCI-H2009 CTRP2 6.5789 9.1055 4.1051 1.7905
HCC2935 CTRP2 6.6069 8.3531 4.4397 0.6938
NCI-H810 CTRP2 6.6182 8.2639 4.4808 0.6168
NCI-H841 CTRP2 6.6182 8.6494 4.323 1.0311
HCC1588 CTRP2 6.6496 8.5928 4.3622 0.8888
NCI-H520 CTRP2 6.6832 9.2663 4.092 1.7358
SW1271 CTRP2 6.6853 11.7779 2.9275 6.1733
NCI-H1341 CTRP2 6.6874 7.9997 4.6116 0.264
NCI-H1155 CTRP2 6.693 9.0004 4.2126 1.3223
NCI-H460 CTRP2; CTRP1 6.7201 7.869 4.6856 0.1422
NCI-H146 CTRP2 6.7229 8.2947 4.5151 0.4357
LC-1/sq-SF CTRP2 6.7358 8.1092 4.5906 0.2884
NCI-H2228 CTRP2 6.74 9.0159 4.2303 1.2266
NCI-H1568 CTRP2 6.7745 9.5611 4.0128 2.0605
NCI-H1563 CTRP2 6.7772 13.5159 2.1515 9.1082
NCI-H522 CTRP2 6.8491 14.631 1.6593 10.8972
NCI-H2196 CTRP2 6.8532 8.514 4.4867 0.4716
HCC1438 CTRP2 6.8576 8.4913 4.4973 0.4145
SHP-77 CTRP2 6.861 8.1456 4.6262 0.1705
NCI-H2126 CTRP2 6.8766 8.0911 4.6513 0.1315
NCI-H1623 CTRP2 6.8809 9.6717 4.0226 1.9174
NCI-H650 CTRP2 6.8976 8.8519 4.3742 0.6952
NCI-H446 CTRP2 6.9051 9.1155 4.2709 0.9791
NCI-H226 CTRP2 6.9123 8.4132 4.5491 0.2863
LCLC-103H CTRP2 6.9172 8.0838 4.6686 0.1024
COLO 699 CTRP2 6.9469 9.2788 4.2239 1.089
DV-90 CTRP2 6.986 8.5948 4.5115 0.3562
NCI-H2171 CTRP2 7.0011 8.3383 4.6104 0.171
NCI-H1573 CTRP2 7.0111 8.6041 4.5182 0.3103
HCC1195 CTRP2 7.0132 8.5933 4.523 0.3004
HCC44 CTRP2 7.0354 9.5326 4.1621 1.2111
NCI-H1755 CTRP2; CTRP1 7.0428 8.9303 4.4218 0.5414
HCC1171 CTRP2 7.0483 9.0534 4.3625 0.6413
SK-LU-1 CTRP2; CTRP1 7.0591 8.8822 4.4473 0.4747
DMS 79 CTRP2 7.0987 16.3332 1.007 12.9142
NCI-H2122 CTRP2; CTRP1 7.105 8.7103 4.5306 0.2869
DMS 454 CTRP2 7.1098 9.9311 4.0319 1.5609
NCI-H1435 CTRP2 7.1133 8.7256 4.5142 0.2832
VMRC-LCD CTRP2 7.1188 8.7103 4.522 0.2868
NCI-H1915 CTRP2 7.129 8.4932 4.6033 0.1415
NCI-H1693 CTRP2 7.1422 8.8787 4.4693 0.3835
LCLC-97TM1 CTRP2 7.1575 9.2305 4.3415 0.636
DMS 273 CTRP2 7.1619 8.5458 4.597 0.143
LOU-NH91 CTRP2 7.1737 9.3828 4.2888 0.7608
Calu-1 CTRP2 7.1746 17.2197 0.6279 14.1263
HCC366 CTRP2 7.1949 9.4178 4.2845 0.7599
HCC827 CTRP2 7.2037 10.3546 3.8995 1.9143
NCI-H1781 CTRP1 7.2093 8.8147 4.5334 0.5361
NCI-H838 CTRP2 7.2117 8.6131 4.5918 0.1497
T3M-10 CTRP2; CTRP1 7.2181 9.2297 4.382 0.5898
HARA [Human squamous cell lung carcinoma] CTRP2 7.226 9.5475 4.2471 0.8406
NCI-H596 CTRP1 7.2338 9.0763 4.4468 0.8635
NCI-H358 CTRP2 7.2598 10.3314 3.939 1.7367
RERF-LC-MS CTRP2 7.2686 8.966 4.4875 0.2813
NCI-H1339 CTRP2 7.2854 8.9977 4.4825 0.2848
NCI-H1385 CTRP2 7.3086 11.8794 3.2788 4.0189
NCI-H2291 CTRP2 7.3126 10.6967 3.8097 2.1181
RERF-LC-Ad2 CTRP2 7.3133 8.7811 4.5703 0.1571
NCI-H2110 CTRP2 7.3195 10.0068 4.105 1.1786
NCI-H1838 CTRP2 7.3273 9.0157 4.4923 0.2559
HCC4006 CTRP2 7.3279 8.6983 4.6041 0.113
NCI-H23 CTRP2 7.3313 9.0003 4.4994 0.2434
NCI-H2141 CTRP2 7.34 8.9539 4.5193 0.2104
NCI-H1355 CTRP2 7.3466 9.4273 4.3472 0.5318
NCI-H292 CTRP2 7.3556 9.473 4.3336 0.5583
NCI-H647 CTRP2 7.3573 9.8613 4.182 1.0042
NCI-H196 CTRP2 7.3791 8.8899 4.5564 0.1511
NCI-H1703 CTRP2 7.3972 8.9351 4.5472 0.1703
NCI-H526 CTRP2 7.401 8.832 4.5843 0.1148
NCI-H2081 CTRP2 7.4048 9.0706 4.5022 0.2197
NCI-H1666 CTRP2 7.4055 9.5043 4.3428 0.5158
SK-MES-1 CTRP2 7.4247 9.3394 4.4124 0.3925
HCC78 CTRP2 7.4259 8.909 4.5667 0.1301
NCI-H69 CTRP2 7.4306 9.3668 4.4047 0.3789
NCI-H322 CTRP2 7.432 8.9276 4.5624 0.1339
NCI-H2172 CTRP2 7.4526 8.7843 4.6186 0.0752
NCI-H661 CTRP2 7.469 9.2113 4.4763 0.2427
KNS-62 CTRP2 7.4783 9.1712 4.4942 0.2135
NCI-H1395 CTRP2 7.4871 14.6172 2.1088 8.2451
HCC2108 CTRP2 7.495 8.989 4.5639 0.1216
NCI-H1944 CTRP2 7.4955 9.1856 4.4955 0.2075
LXF 289 CTRP2 7.4997 9.2765 4.4647 0.2527
EPLC-272H CTRP2 7.5016 9.5206 4.3763 0.4083
EKVX CTRP2 7.5073 16.9896 0.9791 12.3822
NCI-H1793 CTRP2 7.5145 13.2783 2.7588 5.7327
NCI-H2023 CTRP2 7.6042 9.2925 4.4982 0.1798
NCI-H1651 CTRP2 7.6207 16.6309 1.2323 11.3087
Lu-65 CTRP2 7.6495 9.3247 4.5035 0.164
NCI-H2170 CTRP2 7.6885 9.331 4.5154 0.1531
NCI-H211 CTRP2 7.6914 9.4246 4.484 0.1802
COR-L95 CTRP2 7.7043 9.0736 4.6081 0.0619
CAL-12T CTRP2 7.706 9.3778 4.5056 0.1511
NCI-H441 CTRP2; CTRP1 7.7189 12.679 3.171 4.0257
NCI-H2030 CTRP2 7.7554 9.4163 4.51 0.1376
HCC15 CTRP2; CTRP1 7.7689 11.0919 3.8896 1.5513
RERF-LC-A1 CTRP2 7.7923 9.2646 4.5744 0.0733
Calu-3 CTRP2 7.8397 9.6572 4.4571 0.1846
NCI-H1184 CTRP2 7.8513 9.8641 4.3883 0.2785
NCI-H1792 CTRP2 7.8663 10.2721 4.2446 0.5342
Calu-6 CTRP2 7.8921 9.418 4.5573 0.076
NCI-H1299 CTRP2 7.9006 10.2445 4.2689 0.4724
PC-14 CTRP2 7.915 9.663 4.4822 0.1417
NCI-H1869 CTRP2 7.9334 10.0337 4.3589 0.3027
ChaGo-K-1 CTRP2 7.9362 9.5658 4.5228 0.1062
NCI-H1373 CTRP2 7.9491 9.6383 4.5028 0.1158
NCI-H2342 CTRP2 7.9552 9.8109 4.4456 0.1764
NCI-H727 CTRP2 7.9625 9.9809 4.3887 0.2502
NCI-H1650 CTRP2 7.9663 13.2043 3.0655 4.0792
NCI-H2405 CTRP2 8.0018 10.0159 4.391 0.2378
A-549 CTRP2 8.2099 10.5508 4.279 0.3547
EBC-1 CTRP2 8.2899 9.8567 4.5464 0.0499
LUDLU-1 CTRP2 8.7072 17.7506 1.4229 9.1424
COR-L105 CTRP2 8.8895 10.724 4.4615 0.0553
DMS 114 CTRP2 9.3907 18.8182 1.3545 8.5429
HCC1833 CTRP2 9.6481 20.72 0.6306 10.6436
HOP-92 CTRP2 9.6565 24.2235 -1.027 15.6396
HCC2279 CTRP2 10.5002 21.5702 0.7642 9.2159
HOP-62 CTRP2 10.5072 24.0943 -0.4037 12.7769
DMS 53 CTRP2 10.8274 37.5289 -6.6667 25.6781
NCI-H2286 CTRP2 11.5643 25.877 -0.5697 12.0202
Hs 888.Lu CTRP2 7.7446 9.6524 4.4234 0.2524
⏷ Show the Full List of 146 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 5.6896 9.3741 3.3909 5.7987
H-STS CTRP2 6.1938 7.2351 4.6954 0.2868
P-STS CTRP2 6.4502 8.1618 4.4429 0.8469
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 6.063 8.1599 4.2314 1.8795
Yamato-SS CTRP2 6.7515 8.023 4.6283 0.1967
TE 441.T CTRP2 5.3329 6.4541 4.5631 1.5293
Tm87-16 CTRP2 5.4775 7.0612 4.3701 2.0995
TE 617.T CTRP2 5.6192 8.6593 3.6907 5.0053
BT-12 CTRP2 5.9755 7.0576 4.6672 0.4612
TTC-709 CTRP2 6.2171 8.3863 4.22 1.7503
GCT CTRP2 6.3922 9.0751 4.0107 2.3297
HT-1080 CTRP2; CTRP1 6.4266 7.7365 4.6163 0.4085
Rh41 CTRP2 6.5025 9.0265 4.0971 1.8952
MES-SA CTRP2 6.74 8.1171 4.5894 0.2702
BT-16 CTRP2 6.751 8.0031 4.6353 0.1854
SK-UT-1 CTRP2 6.95 8.7537 4.4361 0.5119
Hs 729.T CTRP2 6.956 9.5853 4.0995 1.5745
KYM-1 CTRP2 7.0249 8.5342 4.5493 0.2491
SW982 CTRP2 7.0771 8.4546 4.5977 0.1601
Rh18 CTRP2 7.1341 8.592 4.5704 0.1856
RD CTRP2 7.4529 9.2121 4.4699 0.2571
RKN CTRP2 7.5102 8.7755 4.6413 0.0526
G-401 CTRP2 7.6939 10.6945 4.0031 1.2214
G-402 CTRP2 8.1195 10.19 4.3733 0.2358
SK-LMS-1 CTRP2 8.1665 9.6468 4.5741 0.0434
A-204 CTRP2 8.2251 15.4796 2.1793 7.0214
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.9987 8.494 4.5537 0.2674
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 7.3117 8.9649 4.5046 0.2404
COV644 CTRP2; CTRP1 5.5682 7.5738 4.1965 2.7494
COV434 CTRP2 5.6597 13.6215 1.2572 14.4488
FU-OV-1 CTRP2 6.4444 8.5048 4.2946 1.2664
HEY A8 CTRP2 6.5983 8.3354 4.4429 0.6906
OAW42 CTRP2 6.6006 7.8355 4.6375 0.2278
COV362 CTRP2 6.6363 8.718 4.3033 1.1555
OVK18 CTRP2 6.6576 8.2163 4.5171 0.4628
OV7 CTRP2; CTRP1 6.7192 8.5785 4.4149 0.7407
TOV-21G CTRP2 6.7386 7.9229 4.6593 0.1517
SNU-8 CTRP2 6.7735 8.0548 4.6253 0.1953
JHOS-2 CTRP2 6.8509 8.3151 4.5607 0.3061
RMG-I CTRP2 6.8931 9.2532 4.2079 1.1775
OVISE CTRP2 6.9162 8.2141 4.6227 0.1621
OV56 CTRP2 6.9489 8.0819 4.6806 0.0845
SK-OV-3 CTRP2 7.003 9.2377 4.2678 0.9221
Caov-3 CTRP2; CTRP1 7.0417 8.9645 4.408 0.575
ONCO-DG-1 CTRP2 7.0853 8.8555 4.4546 0.4101
ES2 CTRP2 7.0992 8.1964 4.6942 0.0539
JHOM-1 CTRP2 7.3139 8.7059 4.5965 0.1241
EFO-21 CTRP2 7.3265 9.031 4.4865 0.2847
EFO-27 CTRP2 7.3501 9.0144 4.5015 0.2517
SNU-119 CTRP2 7.3987 8.9692 4.5358 0.1735
Kuramochi CTRP2 7.4799 9.3659 4.4246 0.3255
OVSAHO CTRP2 7.5393 8.8767 4.6175 0.0667
DOV13 CTRP2 7.5551 9.016 4.576 0.1003
OVCAR-5 CTRP2 7.5592 9.6666 4.3454 0.4482
MCAS CTRP2 7.6211 9.1093 4.5674 0.0994
TOV-112D CTRP2 7.6256 9.3869 4.4729 0.2092
OC 314 CTRP2 7.6338 9.078 4.5824 0.0844
OV-90 CTRP2; CTRP1 7.7091 9.5238 4.4699 0.2177
OVTOKO CTRP2 7.7256 9.6878 4.4035 0.2884
TYK-nu CTRP2; CTRP1 7.7956 9.3657 4.5558 0.1022
OVCAR-8 CTRP2 7.8409 9.3495 4.5627 0.0772
A2780 CTRP2 7.9753 9.6815 4.4973 0.1174
IGROV-1 CTRP2 8.0058 9.695 4.5034 0.1076
OAW28 CTRP2 8.2097 10.1682 4.4139 0.168
OVCAR-4 CTRP2 8.8457 18.3871 1.2126 9.6997
RMUG-S CTRP1 8.8706 18.9161 0.9912 17.697
JHOC-5 CTRP2 8.9761 16.0641 2.3637 5.505
SNU-840 CTRP2; CTRP1 13.9812 26.5585 0.5186 6.6989
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ACC-MESO-1 CTRP2 6.4942 8.076 4.4989 0.6009
JL-1 CTRP2 6.6062 8.0026 4.5772 0.3727
NCI-H2452 CTRP2 6.7765 10.0064 3.815 2.628
MPP 89 CTRP2 7.1308 8.9117 4.4523 0.4249
NCI-H28 CTRP2 7.181 8.943 4.4611 0.3597
MSTO-211H CTRP2 7.3237 9.0659 4.4727 0.29
NCI-H2052 CTRP2 7.5802 9.2852 4.4919 0.1933
IST-Mes1 CTRP2 8.0802 13.2688 3.1018 3.833
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP CTRP2 6.2644 10.6789 3.1677 5.8175
22Rv1 CTRP2 6.4744 10.2718 3.5048 4.1749
PaCa-3 CTRP2 6.6973 9.3881 4.0463 2.0152
DU145 CTRP2 7.5805 9.1932 4.5241 0.152
LNCaP clone FGC CTRP2 7.9104 9.8811 4.4045 0.257
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 5.9821 11.0295 2.7928 7.7863
A-253 CTRP2 7.2416 8.8695 4.512 0.248
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1 CTRP2 5.5439 9.0963 3.4182 5.9292
Fu97 CTRP2 5.9884 7.6965 4.3979 1.3465
SNU-620 CTRP2 6.0305 7.662 4.4373 1.1628
GSU CTRP2 6.0394 6.8488 4.7769 0.1595
NCI-N87 CTRP2 6.0654 10.2645 3.2286 5.8699
GSS CTRP2 6.2325 7.7988 4.486 0.8216
NCC-StC-K140 CTRP2 6.3355 10.5143 3.2963 5.5646
SNU-5 CTRP2 6.3387 8.0583 4.4304 0.9127
MKN45 CTRP2 6.4826 7.5697 4.6881 0.1754
ECC12 CTRP2 6.6262 7.7512 4.678 0.1519
MKN1 CTRP2 6.6524 8.2429 4.5044 0.4965
SNU-16 CTRP2 6.7044 8.0709 4.5921 0.2777
NUGC-3 CTRP2 6.7597 8.6631 4.3861 0.7465
SNU-601 CTRP2 6.7662 12.8001 2.4908 7.789
HuG1-N CTRP2 6.8738 14.4594 1.7607 10.4722
SH-10-TC CTRP2 7.0613 8.1368 4.7011 0.0563
23132/87 CTRP2 7.0753 8.4451 4.6004 0.1568
SNU-719 CTRP2 7.1366 13.5292 2.3935 7.6385
AGS CTRP2 7.205 8.774 4.5323 0.2254
Hs 746.T CTRP2 7.2077 10.1386 3.9942 1.6019
HGC-27 CTRP2 7.2416 12.9236 2.751 6.1103
MKN7 CTRP2 7.3014 8.8168 4.5534 0.1832
KATO III CTRP2 7.333 8.9644 4.5129 0.2376
SNU-216 CTRP2 7.4025 9.3861 4.3861 0.4258
LMSU CTRP2 7.6729 9.8392 4.3273 0.4415
IM95 CTRP2 7.7311 9.9549 4.3079 0.4583
SNU-668 CTRP2 7.7701 12.9923 3.0466 4.3587
ECC10 CTRP2 7.9073 9.5297 4.525 0.1008
NUGC-4 CTRP2 8.139 16.592 1.6012 9.2458
KE-39 CTRP2 8.2207 11.4475 3.9443 1.065
MKN74 CTRP2 8.4341 10.5079 4.3773 0.171
SNU-685 CTRP2 6.8665 8.2558 4.5886 0.2461
SNU-1077 CTRP2 7.0764 8.8157 4.4659 0.3901
SNG-M CTRP2 7.5547 9.3126 4.4727 0.2263
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-62 CTRP2 6.0046 7.7944 4.3632 1.4558
SW579 CTRP2 6.0285 7.438 4.5341 0.894
FTC-238 CTRP2 6.9546 8.3144 4.6015 0.184
B-CPAP CTRP2 6.9592 8.2539 4.6246 0.1494
FTC-133 CTRP2 7.0594 8.7605 4.4796 0.3949
CGTH-W-1 CTRP2 7.1129 8.6196 4.5525 0.2184
TT2609-C02 CTRP2 7.1436 9.7872 4.1097 1.2906
BHT-101 CTRP2 7.2256 8.5698 4.6118 0.1137
TT CTRP2 7.2815 9.0579 4.459 0.3283
8305C CTRP2 7.4392 9.0679 4.5161 0.1915
ML-1 [Human leukemia] CTRP2 7.5179 9.0468 4.5522 0.1307
8505C CTRP2 7.9072 9.4233 4.5607 0.072
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1214 CTRP2 5.8344 10.3951 2.9955 7.1955
BICR 22 CTRP2 5.9712 7.4683 4.4898 1.0369
SCC-25 CTRP2 6.2484 8.5961 4.1433 1.998
YD-10B CTRP2 6.2845 10.8795 3.0845 6.1242
HSC-4 CTRP2 6.4462 8.1939 4.4276 0.8393
SNU-46 CTRP2 6.5062 9.0355 4.0952 1.8982
CAL-33 CTRP2 6.5532 8.7318 4.2544 1.3044
HSC-3 CTRP2 6.5754 8.1152 4.5203 0.4978
SNU-1076 CTRP2 6.6619 8.0333 4.5888 0.3004
BICR 31 CTRP2 6.7428 9.1043 4.1941 1.3406
YD-8 CTRP2 6.7594 11.8779 2.9296 6.0613
BICR 16 CTRP2 6.8274 8.8623 4.3373 0.8399
PE/CA-PJ49 CTRP2 6.8482 8.4037 4.5265 0.3806
Detroit 562 CTRP2 6.9078 8.6755 4.448 0.5042
BICR 18 CTRP2 6.924 8.6781 4.454 0.4825
FaDu CTRP2 6.9529 8.2693 4.6169 0.1732
BHY CTRP2 6.9598 9.1533 4.2817 0.9111
SCC-9 CTRP2 6.9625 9.1722 4.2753 0.9276
BICR 6 CTRP2 6.9919 8.2495 4.6382 0.1338
CAL-27 CTRP2 7.0175 8.3786 4.6023 0.1673
PE/CA-PJ15 CTRP2 7.0351 8.9582 4.3938 0.5709
SNU-899 CTRP2 7.1883 8.657 4.5677 0.1766
HSC-2 CTRP2 7.2077 8.4744 4.6381 0.0891
PE/CA-PJ41 (clone D2) CTRP2 7.2188 15.6107 1.4454 11.13
SNU-1041 CTRP2 7.2395 10.1138 4.0209 1.4921
SCC-4 CTRP2 7.4231 9.1664 4.4749 0.2573
SNU-1066 CTRP2 7.4463 8.8864 4.5817 0.1104
BICR 56 CTRP2 7.4998 9.1133 4.5225 0.1698
PE/CA-PJ34 (clone C12) CTRP2 7.625 8.8961 4.6401 0.0443
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J CTRP2 5.1409 6.7818 4.2548 3.1374
253J-BV CTRP2 5.7696 8.3574 3.9464 3.389
CAL-29 CTRP2 5.9138 7.644 4.3778 1.502
639V CTRP2 6.3601 7.5723 4.6371 0.3238
HT-1197 CTRP2 6.4111 8.2534 4.3848 0.9995
RT-4 CTRP2 6.521 8.7457 4.2312 1.4108
T24 CTRP2 6.601 17.068 0.2755 16.2695
JMSU-1 CTRP2 6.6697 8.5247 4.3998 0.7658
SCaBER CTRP2 6.7869 9.576 4.0131 1.9102
UM-UC-1 CTRP2 6.9801 10.385 3.7626 2.6027
KU-19-19 CTRP2 7.031 8.1778 4.6768 0.0765
TCCSUP CTRP2 7.0637 8.8364 4.4528 0.4229
HT-1376 CTRP2 7.0888 9.0731 4.3726 0.5951
RT-112 CTRP2 7.0924 8.535 4.5749 0.1891
VM-CUB-1 CTRP2 7.159 9.6747 4.1639 1.1171
647V CTRP2 7.265 8.5446 4.6343 0.0847
UM-UC-3 CTRP2 7.2882 8.7902 4.5579 0.1678
BC-3C CTRP2 7.3647 8.7718 4.592 0.1124
SW1710 CTRP2 7.6203 9.3853 4.4715 0.2124
KMBC-2 CTRP2 7.8294 9.8947 4.3689 0.3155
J82 CTRP2 7.8382 9.4868 4.5153 0.1193
U-BLC1 CTRP2 9.8786 21.9424 0.2044 11.7147
5637 CTRP2 9.9877 23.8128 -0.6088 14.021
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 6.3666 7.406 4.7023 0.187

References

1 G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev. 2002 Jul 15;16(14):1779-91.
2 Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines. J Med Chem. 2010 Aug 12;53(15):5844-57.