Details of the Drug

General Information of Drug (ID: DMCWVS7)

Drug Name
CCX-025
Synonyms CCX-807; CCR9 chemokine receptor-targeting therapeutic (gastrointestinal diseases), ChemoCentryx
Indication
Disease Entry ICD 11 Status REF
Crohn disease DD70 Phase 1 [1]
Cross-matching ID
TTD ID
D00YXU

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
C-C chemokine receptor type 9 (CCR9) TTIPS8B CCR9_HUMAN Antagonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Crohn disease
ICD Disease Classification DD70
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
C-C chemokine receptor type 9 (CCR9) DTT CCR9 7.74E-01 0.02 0.22
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of ChemoCentryx Inc.
2 Targeting T-cell migration in inflammatory bowel disease. J Intern Med. 2012 Nov;272(5):411-29.