Details of the Drug | DrugMAP

General Information of Drug (ID: DMCZB9N)

Drug Name

MK-8666

Indication

Disease Entry	ICD 11	Status	REF
Type-2 diabetes	5A11	Phase 1	[1]

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C29H31NO6S
Canonical SMILES: CC1=CC(=CC(=C1C2=CC=CC(=C2)COC3=NC=C4C5C(C5C(=O)O)CC4=C3)C)OCCCS(=O)(=O)C
InChI: InChI=1S/C29H31NO6S/c1-17-10-22(35-8-5-9-37(3,33)34)11-18(2)26(17)20-7-4-6-19(12-20)16-36-25-14-21-13-23-27(24(21)15-30-25)28(23)29(31)32/h4,6-7,10-12,14-15,23,27-28H,5,8-9,13,16H2,1-3H3,(H,31,32)/t23-,27-,28+/m1/s1
InChIKey: CODQKEMYZZKQAE-QPVYNBJUSA-N

Cross-matching ID

PubChem CID: 73051869
ChEBI ID: CHEMBL4297471
CAS Number: 1544739-75-4
UNII: 11612L5SPI
DrugBank ID: DB14937
TTD ID: D0K0IM

Drug-Molecule Activity Atlas (DMA)^NEW

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Drug ADMET Endpoint Profile (DAE)^NEW

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References

1	ClinicalTrials.gov (NCT01971554) Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of MK-8666 in Participants With Type 2 Diabetes Mellitus (MK-8666-003). U.S. National Institutes of Health.