Details of the Drug

General Information of Drug (ID: DMD82LM)

Drug Name

AMT-030

Synonyms

AAV gene therapy (AGT, hyperoxaluria), AMT; Adeno-associated virus gene therapy (alanine:glyoxylate aminotransferase, hyperoxaluria), Amsterdam Molecular Therapeutics

Indication

Disease Entry	ICD 11	Status	REF
Hyperoxaluria	5C51.2	Terminated	[1]

Cross-matching ID

TTD ID: D0M9WX

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Alanine glyoxylate aminotransferase (AGXT)	TTF5NVW	SPYA_HUMAN	Modulator	[2]

Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024084)
2	Adenovirus-associated virus vector-mediated gene transfer in hemophilia B. N Engl J Med. 2011 Dec 22;365(25):2357-65.