Details of the Drug

General Information of Drug (ID: DMD83WO)

Drug Name
AST-1306
Synonyms Allitinib; Allitinib tosylate
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 448.9
Logarithm of the Partition Coefficient (xlogp) 5.4
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C24H18ClFN4O2
IUPAC Name
N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]prop-2-enamide
Canonical SMILES
C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OCC4=CC(=CC=C4)F)Cl
InChI
InChI=1S/C24H18ClFN4O2/c1-2-23(31)29-17-6-8-21-19(11-17)24(28-14-27-21)30-18-7-9-22(20(25)12-18)32-13-15-4-3-5-16(26)10-15/h2-12,14H,1,13H2,(H,29,31)(H,27,28,30)
InChIKey
MVZGYPSXNDCANY-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
24739943
ChEBI ID
CHEBI:91467
CAS Number
897383-62-9
TTD ID
D04OLK
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Epidermal growth factor receptor (EGFR) TTGKNB4 EGFR_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Epidermal growth factor receptor (EGFR) DTT EGFR 5.84E-05 0.32 0.55
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.2973 4.3132 3.2061 13.4057
HuO9 GDSC1 0.2266 2.6723 0.1718 51.1278
H-EMC-SS GDSC1 0.6879 3.196 0.597 45.6971
NOS-1 [Human HNSCC] GDSC1 0.7391 2.607 0.7143 44.883
EW-24 GDSC1 0.981 4.9567 0.4847 43.4153
ES5 GDSC1 1.0751 3.8582 0.8935 41.3937
ES7 GDSC1 1.1229 3.6235 0.9936 40.6113
EW-16 GDSC1 1.2094 4.7504 0.7991 40.6859
NY GDSC1 1.2119 3.256 1.1484 39.2189
SaOS-2 GDSC1 1.2893 4.4743 0.9695 39.437
ES4 GDSC1 1.3607 7.0938 0.0653 41.6907
U2OS GDSC1 1.3706 3.152 1.3291 37.1339
EW-13 GDSC1 1.526 2.6768 1.521 34.9803
SK-ES-1 GDSC1 1.546 2.9442 1.5299 34.7982
EW-18 GDSC1 1.6563 2.7871 1.6505 33.3562
EW-22 GDSC1 1.9058 3.6007 1.8413 30.6057
HuO-3N1 GDSC1 1.9999 4.6965 1.6765 31.03
CHSA8926 GDSC1 2.0045 3.7182 1.9284 29.4487
MHH-ES-1 GDSC1 2.0239 3.6207 1.9648 29.0987
CAL-72 GDSC1 2.1426 3.1047 2.1366 27.2793
CAL-78 GDSC1 2.1841 3.8805 2.0929 27.3045
CADO-ES1 GDSC1 2.223 3.6078 2.1795 26.5125
ES8 GDSC1 2.229 3.5597 2.192 26.3961
SJSA-1 GDSC1 2.3493 3.875 2.2726 25.1495
ES1 GDSC1 2.3579 3.8307 2.2898 24.9857
G-292 clone A141B1 GDSC1 2.3873 3.7412 2.3361 24.5092
HOS GDSC1 2.5062 3.3322 2.5002 22.7339
EW-1 GDSC1 2.5453 3.8476 2.4889 22.5689
EW-7 GDSC1 2.5458 4.1289 2.4327 22.9351
SK-PN-DW GDSC1 2.555 3.6395 2.5282 22.2569
MG-63 GDSC1 2.615 4.1507 2.5029 22.064
ES6 GDSC1 2.6312 3.9495 2.5635 21.5691
EW-3 GDSC1 2.6703 4.7751 2.3782 22.5937
TC-71 GDSC1 3.3337 4.2621 3.2592 12.8394
A-673 GDSC1 3.636 9.4965 1.1429 25.5903
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 152 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 2.2465 3.5898 2.2068 26.1946
A4/Fukuda GDSC1 -1.1695 1.4238 -1.1918 67.1191
SIG-M5 GDSC1 0.102 2.2329 0.0773 52.6608
SU-DHL-6 GDSC1 0.2087 2.2229 0.1883 51.3799
GDM-1 GDSC1 0.7961 3.3617 0.6873 44.4556
NK-92MI GDSC1 0.8071 2.5435 0.7888 44.0161
QIMR-WIL GDSC1 0.8448 2.2714 0.8387 43.495
NALM-6 GDSC1 0.8683 2.6006 0.8488 43.2621
DoHH2 GDSC1 0.9687 2.184 0.9661 41.9305
SU-DHL-16 GDSC1 0.9876 2.0327 0.9867 41.6845
ALL-SIL GDSC1 1.0161 2.8056 0.9885 41.465
ALL-PO GDSC1 1.0513 2.8314 1.0231 41.0311
RS4;11 GDSC1 1.0675 3.1739 1.0052 40.9913
HAL-01 GDSC1 1.1218 2.8634 1.0943 40.1514
Ku812 GDSC1 1.1763 2.7361 1.1596 39.4159
KE-37 GDSC1 1.1825 2.7366 1.166 39.3378
OCI-AML-2 GDSC1 1.1896 2.4501 1.1847 39.1833
Loucy GDSC1 1.2 2.6385 1.1889 39.089
MV4-11 GDSC1 1.2593 2.3964 1.2565 38.3001
RCH-ACV GDSC1 1.2805 2.8468 1.2607 38.1341
MOLT-16 GDSC1 1.3019 3.0004 1.2714 37.927
SR GDSC1 1.3287 2.5599 1.3234 37.448
MLMA GDSC1 1.3492 2.1389 1.349 37.1607
ROS-50 GDSC1 1.3662 3.9012 1.2006 37.8377
MY-M12 GDSC1 1.3933 3.4784 1.3103 37.0818
JJN-3 GDSC1 1.4011 3.4899 1.3169 36.9916
BV-173 GDSC1 1.4158 3.4484 1.3392 36.7685
HC-1 GDSC1 1.507 3.0327 1.4833 35.3308
MOLT-13 GDSC1 1.5391 2.8635 1.5273 34.8586
SUP-B15 GDSC1 1.5399 3.0066 1.5196 34.8997
697 GDSC1 1.5574 2.7585 1.5504 34.6
ST486 GDSC1 1.5578 3.0094 1.5379 34.6737
DB GDSC1 1.5873 2.9611 1.5718 34.2785
THP-1 GDSC1 1.5936 3.1721 1.5621 34.297
OCI-M1 GDSC1 1.5955 3.5962 1.5086 34.6013
SU-DHL-5 GDSC1 1.6119 2.2242 1.6119 33.875
DEL GDSC1 1.6178 3.2389 1.581 34.0275
P32/ISH GDSC1 1.6423 2.9514 1.6292 33.577
PF-382 GDSC1 1.6489 3.3423 1.6023 33.6994
LAMA-84 GDSC1 1.6499 3.487 1.5841 33.8016
Karpas-45 GDSC1 1.655 2.4231 1.6547 33.3385
Karpas-620 GDSC1 1.6577 3.6548 1.5656 33.8613
OCI-Ly19 GDSC1 1.6723 3.2652 1.6358 33.3458
NU-DUL-1 GDSC1 1.6946 3.2095 1.6648 33.0264
CESS GDSC1 1.7151 2.9799 1.7029 32.6614
HH [Human lymphoma] GDSC1 1.7185 3.5644 1.6459 32.9892
RPMI-8402 GDSC1 1.7477 3.6185 1.6687 32.6651
MOLP-8 GDSC1 1.7714 2.8714 1.7653 31.9197
Ramos.2G6.4C10 GDSC1 1.7922 2.5255 1.7919 31.6233
RPMI-8866 GDSC1 1.8262 3.2038 1.8032 31.3406
CCRF-CEM GDSC1 1.8285 3.0681 1.8151 31.2514
PL-21 GDSC1 1.883 5.2668 1.3534 33.5664
ATN-1 GDSC1 1.8873 4.2052 1.6959 31.6163
ML-2 GDSC1 1.8914 2.9891 1.8838 30.4292
DND-41 GDSC1 1.9205 3.5703 1.8616 30.3879
OCI-AML-5 GDSC1 1.9461 3.5312 1.8944 30.0232
MEG-01 GDSC1 1.9634 4.086 1.8084 30.454
P30/OHK GDSC1 1.9781 3.443 1.9396 29.5404
ME1 GDSC1 2.0043 3.6593 1.9379 29.3891
Hs 445 GDSC1 2.0234 3.5895 1.9689 29.0759
RPMI-6666 GDSC1 2.0406 2.9727 2.0367 28.5405
K-562 GDSC1 2.0469 3.3181 2.0247 28.5778
TUR GDSC1 2.0543 3.6121 1.9987 28.6967
HT GDSC1 2.0572 3.586 2.0055 28.6355
GA-10 GDSC1 2.076 2.9474 2.0733 28.0909
Reh GDSC1 2.0808 3.4604 2.0464 28.2317
EM-2 GDSC1 2.0984 3.8629 2.0035 28.3967
KOPN-8 GDSC1 2.1029 3.9696 1.9865 28.4783
KCL-22 GDSC1 2.1269 3.8784 2.0313 28.047
Karpas-231 GDSC1 2.1314 4.09 1.9905 28.2803
KMS-12-BM GDSC1 2.1738 4.5713 1.9051 28.5702
VL51 GDSC1 2.1967 3.9569 2.0911 27.2409
NKM-1 GDSC1 2.2289 3.8801 2.1414 26.7218
VAL GDSC1 2.2319 3.4645 2.2055 26.292
HL-60 GDSC1 2.251 3.0966 2.2475 25.9088
Jurkat GDSC1 2.2523 3.3925 2.2334 25.9895
EoL-1 GDSC1 2.2527 4.7668 1.9283 27.9557
RPMI-8226 GDSC1 2.2562 3.6714 2.2061 26.1404
MHH-PREB-1 GDSC1 2.2749 3.3964 2.2568 25.7019
BC-1 GDSC1 2.2846 3.4709 2.2604 25.6193
KMOE-2 GDSC1 2.2925 3.7093 2.2394 25.7056
CA46 GDSC1 2.2945 3.5695 2.2603 25.559
L-363 GDSC1 2.3214 3.7257 2.2679 25.3472
MC116 GDSC1 2.3286 3.5137 2.3025 25.0816
CTV-1 GDSC1 2.3329 3.4365 2.3142 24.9808
SUP-T1 GDSC1 2.3429 3.563 2.3123 24.9319
SU-DHL-10 GDSC1 2.3447 2.989 2.344 24.7193
KG-1 GDSC1 2.3721 3.7102 2.3245 24.6759
GR-ST GDSC1 2.3755 5.8846 1.6337 29.0544
BC-3 GDSC1 2.3824 3.47 2.3632 24.3652
HEL GDSC1 2.4232 3.6148 2.3914 23.9357
HDLM-2 GDSC1 2.434 4.0814 2.322 24.3226
L-428 GDSC1 2.4441 4.7756 2.133 25.518
JURL-MK1 GDSC1 2.4586 4.0286 2.3604 23.9248
H9 GDSC1 2.4609 3.7723 2.4103 23.5857
LP-1 GDSC1 2.461 4.7311 2.1663 25.2006
MOLT-4 GDSC1 2.4626 3.4022 2.4517 23.3102
SU-DHL-8 GDSC1 2.4848 4.1855 2.3526 23.8222
OPM-2 GDSC1 2.486 5.7445 1.8077 27.3811
P12-Ichikawa GDSC1 2.5092 3.2153 2.507 22.6728
SUP-HD1 GDSC1 2.5112 4.8039 2.1959 24.7185
MOLM-13 GDSC1 2.5176 4.4872 2.3053 23.9486
IM-9 GDSC1 2.5214 3.8555 2.4618 22.8881
Farage GDSC1 2.5227 3.6777 2.4895 22.7011
EJM GDSC1 2.5275 4.9631 2.1575 24.884
MN-60 GDSC1 2.5531 4.2964 2.3985 23.1194
NOMO-1 GDSC1 2.554 3.886 2.4917 22.4981
BALL-1 GDSC1 2.5541 4.2342 2.4158 22.9985
NB4 GDSC1 2.5557 3.619 2.5312 22.2325
WIL2 NS GDSC1 2.5578 4.1287 2.4458 22.777
KY821 GDSC1 2.5801 3.5783 2.5608 21.8949
BE-13 GDSC1 2.5961 4.4297 2.4079 22.8096
LC4-1 GDSC1 2.6034 3.7313 2.5685 21.7032
TK [Human B-cell lymphoma] GDSC1 2.6043 3.4546 2.5953 21.527
SKM-1 GDSC1 2.6088 3.2889 2.6064 21.4294
CTB-1 GDSC1 2.61 5.4748 2.0487 25.1512
YT GDSC1 2.6199 3.308 2.6172 21.2919
BL-41 GDSC1 2.6827 3.1978 2.6823 20.4926
SU-DHL-4 GDSC1 2.6891 3.271 2.688 20.4172
SUP-M2 GDSC1 2.7041 4.0108 2.6305 20.6967
JSC-1 GDSC1 2.7152 5.4682 2.1622 23.8233
Jiyoye GDSC1 2.7297 4.0903 2.6416 20.473
U-698-M GDSC1 2.7473 3.8317 2.7083 19.9315
Daudi GDSC1 2.8088 4.5606 2.5997 20.3036
SU-DHL-1 GDSC1 2.8176 9.9557 0.1706 33.4717
RL GDSC1 2.8966 3.4384 2.8951 17.8255
Karpas-422 GDSC1 2.9007 4.485 2.7235 18.9397
EB2 GDSC1 2.9341 4.328 2.8056 18.1913
KM-H2 GDSC1 3.0365 3.6912 3.0287 16.1168
P31/FUJ GDSC1 3.0503 3.7846 3.0357 15.9878
U266B1 GDSC1 3.0919 4.0579 3.0413 15.7003
OCI-AML-3 GDSC1 3.1124 5.4789 2.5727 18.8861
A3/Kawakami GDSC1 3.1471 4.6448 2.9391 16.0837
Mono-Mac-6 GDSC1 3.2622 7.7724 1.6498 24.3959
Karpas-299 GDSC1 3.2937 5.3071 2.8342 16.0752
Raji GDSC1 3.5809 6.5315 2.5518 16.823
KMS-11 GDSC1 3.6031 7.0026 2.3438 18.2407
L-540 GDSC1 3.6343 7.062 2.3438 18.105
SK-MM-2 GDSC1 3.8743 6.5851 2.7986 13.706
Sc-1 GDSC1 3.8758 6.9738 2.608 15.1415
EHEB GDSC1 3.898 5.6026 3.3013 9.7282
JVM-2 GDSC1 3.959 6.1262 3.102 11.0166
ARH-77 GDSC1 4.2869 5.5181 3.6944 5.0772
DG-75 GDSC1 4.8918 8.257 2.8068 9.9669
RC-K8 GDSC1 4.9638 7.4812 3.24 6.4622
Granta-519 GDSC1 4.9982 8.1408 2.9426 8.6193
SCC-3 GDSC1 5.1708 8.0949 3.0874 7.0359
AMO1 GDSC1 5.2444 8.2486 3.064 7.0109
WSU-DLCL2 GDSC1 5.7581 6.8926 3.9483 0.3879
JVM-3 GDSC1 5.8812 7.8397 3.6298 1.7862
L-1236 GDSC1 6.0915 9.7582 2.8987 6.1432
WSU-NHL GDSC1 6.3884 8.0599 3.7699 0.6087
⏷ Show the Full List of 152 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC1 -4.3331 3.3266 -4.8715 77.1924
KYAE-1 GDSC1 -2.5792 0.9164 -2.6203 78.443
TE-12 GDSC1 -0.6432 4.8549 -1.2511 57.9512
OACP4 C GDSC1 0.8889 3.8038 0.7031 43.5923
KYSE-220 GDSC1 1.1502 7.7008 -0.4146 43.9635
FLO-1 GDSC1 1.5291 2.8239 1.5189 34.9734
KYSE-50 GDSC1 1.8327 4.5583 1.5373 32.89
SK-GT-4 GDSC1 2.3251 4.5261 2.0837 26.5286
HCE-4 GDSC1 2.6537 3.686 2.6274 21.0194
OACM5.1 C GDSC1 2.8335 4.4875 2.6495 19.8237
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 3.6244 9.6292 1.0667 26.0326
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-SH GDSC1 -2.1903 1.1077 -2.229 75.7244
CHP-212 GDSC1 -2.0154 1.8897 -2.1131 72.4818
NB69 GDSC1 -1.9893 0.9271 -2.012 74.9347
KP-N-YS GDSC1 -1.4213 0.3966 -1.4229 71.1452
NB1 GDSC1 -0.8443 0.9108 -0.8468 64.3097
SJNB-10 GDSC1 -0.3335 2.6656 -0.4207 57.3349
SK-N-MC-IXC GDSC1 -0.0381 0.7294 -0.0381 54.5002
GI-ME-N GDSC1 0.0767 3.4499 -0.1054 52.6419
GOTO GDSC1 0.5789 1.8918 0.5766 46.7962
IMR-5 GDSC1 0.8979 4.9101 0.4094 44.2666
SJNB-12 GDSC1 1.1312 2.877 1.1031 40.0377
SiMa GDSC1 1.3017 3.0774 1.264 37.9699
SJNB-14 GDSC1 1.738 3.6113 1.6594 32.7828
CHP-134 GDSC1 1.7613 3.0533 1.7464 32.101
SK-N-BE(2)-M17 GDSC1 1.9642 13.1493 -2.1833 42.3825
Kelly GDSC1 1.9691 2.583 1.969 29.4112
MHH-NB-11 GDSC1 2.0599 4.2349 1.8765 29.4368
NB(TU)1 GDSC1 2.3228 3.581 2.2889 25.2042
LA-N-6 GDSC1 2.524 3.3487 2.5178 22.5129
SJNB-17 GDSC1 2.6307 5.5148 2.0543 25.0015
NH-12 GDSC1 2.8133 5.2843 2.3403 22.0786
SK-N-FI GDSC1 2.828 4.3616 2.6806 19.6435
SJNB-13 GDSC1 2.8314 3.8875 2.79 18.8959
SJNB-7 GDSC1 2.908 3.9959 2.8541 18.0204
KP-N-YN GDSC1 3.3922 8.5083 1.4111 25.1968
SJNB-5 GDSC1 3.6462 7.006 2.3822 17.7769
SK-N-DZ GDSC1 3.8236 4.4085 3.7522 6.7048
SK-N-AS GDSC1 3.8565 4.2638 3.8286 5.9984
SJNB-6 GDSC1 4.787 6.5415 3.5718 4.4287
TGW GDSC1 5.9992 13.1874 1.1974 17.1219
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 1.7595 2.6931 1.7575 32.0425
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AU565 GDSC1 -5.4302 -0.4424 -5.4912 89.6035
BT-474 GDSC1 -5.318 -0.4307 -5.3756 89.4919
HCC1419 GDSC1 -4.4668 6.2537 -5.8588 71.775
HCC2218 GDSC1 -4.365 3.292 -4.8982 77.3486
MDA-MB-175-VII GDSC1 -4.0964 3.6927 -4.7014 75.7648
OCUB-M GDSC1 -3.174 0.5283 -3.213 82.2604
HCC202 GDSC1 -1.943 4.0632 -2.4463 67.0691
UACC-893 GDSC1 -1.5689 3.5461 -1.9129 65.9878
EFM-192A GDSC1 -0.6128 9.66 -3.0828 54.7009
MDA-MB-330 GDSC1 -0.4735 4.2969 -0.9046 57.1849
MDA-MB-453 GDSC1 -0.0618 4.47 -0.5035 53.5864
HCC1954 GDSC1 0.1576 6.2236 -0.8539 51.2724
EFM-19 GDSC1 0.3433 4.4503 -0.0557 49.7888
Hs 578T GDSC1 0.5122 3.1114 0.4213 47.7792
MDA-MB-361 GDSC1 0.599 4.0355 0.3335 47.0365
HCC38 GDSC1 0.6189 3.7883 0.413 46.7265
MDA-MB-468 GDSC1 0.681 3.0412 0.6109 45.7269
ZR-75-30 GDSC1 0.7441 5.6617 -0.0159 46.2416
HCC2157 GDSC1 1.0117 7.9732 -0.6761 45.194
MRK-nu-1 GDSC1 1.0186 2.6433 1.0018 41.3814
HCC1806 GDSC1 1.1319 5.6329 0.4116 42.4345
COLO 824 GDSC1 1.1656 3.9197 0.9782 40.3436
HCC1569 GDSC1 1.299 3.852 1.1384 38.6259
MFM-223 GDSC1 1.3203 2.7558 1.3073 37.598
HCC1187 GDSC1 1.3322 2.571 1.3266 37.4055
MDA-MB-157 GDSC1 1.3443 4.0246 1.1485 38.2466
HCC1395 GDSC1 1.4879 2.5667 1.4848 35.4446
BT-483 GDSC1 1.5061 3.4823 1.4307 35.6439
CAL-148 GDSC1 1.5433 3.6826 1.4371 35.3581
HCC1599 GDSC1 1.6083 2.6507 1.6052 33.9394
HDQ-P1 GDSC1 1.6459 2.6646 1.643 33.4683
DU4475 GDSC1 1.7647 2.5065 1.7644 31.9675
HCC70 GDSC1 1.8043 3.3265 1.7686 31.693
BT-549 GDSC1 1.8517 3.9926 1.7084 31.7648
HCC1937 GDSC1 1.9123 3.0005 1.9047 30.1679
CAMA-1 GDSC1 1.942 3.2971 1.9165 29.9092
HCC1500 GDSC1 2.0113 3.3083 1.9882 29.0285
CAL-85-1 GDSC1 2.041 9.6092 -0.4002 38.9254
HCC1428 GDSC1 2.1183 2.9353 2.1163 27.5583
MDA-MB-231 GDSC1 2.2076 4.1676 2.0547 27.4103
CAL-51 GDSC1 2.5859 6.0404 1.7863 26.9642
MDA-MB-436 GDSC1 2.625 4.0746 2.5313 21.8175
MCF-7 GDSC1 2.7036 3.5758 2.6904 20.3125
CAL-120 GDSC1 2.8425 7.0106 1.6081 26.691
YMB-1-E GDSC1 2.8952 5.2387 2.4451 20.9135
MDA-MB-415 GDSC1 2.9245 6.035 2.1361 22.9068
T-47D GDSC1 3.1404 7.0061 1.9018 23.3936
Evsa-T GDSC1 3.1734 4.2541 3.0864 14.9246
BT-20 GDSC1 3.4657 6.1863 2.6065 16.9383
UACC-812 GDSC1 3.5776 12.7784 -0.5416 32.6186
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LN-229 GDSC1 1.3142 3.833 1.1589 38.4175
D283 Med GDSC1 1.4161 2.6445 1.41 36.36
YH-13 GDSC1 1.4843 2.713 1.4774 35.5131
D-336MG GDSC1 1.6148 3.5011 1.5445 34.2652
PFSK-1 GDSC1 1.6276 3.2108 1.5941 33.8856
SW1783 GDSC1 1.7371 3.1144 1.7172 32.4344
GI-1 GDSC1 1.9091 2.8994 1.9049 30.1867
Daoy GDSC1 1.9933 3.2721 1.9723 29.2398
MOG-G-CCM GDSC1 2.0114 3.6003 1.9545 29.2409
GB-1 GDSC1 2.109 3.8949 2.0086 28.2999
KS-1 [Human Krukenberg tumour] GDSC1 2.1222 5.9435 1.3437 32.1412
GaMG GDSC1 2.284 3.8243 2.2113 25.9385
AM-38 GDSC1 2.3185 3.567 2.286 25.2488
SF126 GDSC1 2.3978 3.5509 2.3717 24.2168
CAS-1 GDSC1 2.4175 4.3025 2.2488 24.9023
LN-18 GDSC1 2.4262 3.2283 2.4221 23.7224
U-251MG GDSC1 2.4889 3.407 2.4786 22.9772
D-263MG GDSC1 2.565 3.6583 2.5367 22.1413
SNB-75 GDSC1 2.5796 3.7826 2.5359 22.0575
SF539 GDSC1 2.5903 3.749 2.5522 21.8881
U-87MG ATCC GDSC1 2.6085 3.2164 2.6074 21.425
8-MG-BA GDSC1 2.6122 4.1809 2.4926 22.1486
YKG-1 GDSC1 2.6139 3.305 2.6111 21.3679
D-566MG GDSC1 2.6276 3.4345 2.6204 21.2248
D-542MG GDSC1 2.638 3.789 2.5975 21.3072
LNZTA3WT4 GDSC1 2.6534 4.1973 2.5335 21.6363
SK-MG-1 GDSC1 2.6811 3.556 2.6684 20.59
D-247MG GDSC1 2.7413 3.8992 2.6913 20.078
DK-MG GDSC1 2.7807 4.2634 2.6556 20.0827
Hs 683 GDSC1 2.8243 3.6589 2.8099 18.8113
D-392MG GDSC1 2.8582 4.5548 2.6554 19.6452
D-502MG GDSC1 2.8727 8.3932 0.9808 29.8805
H4 GDSC1 2.9424 4.6724 2.7079 18.8164
M059J GDSC1 3.0251 4.3485 2.8993 17.0377
LN-405 GDSC1 3.1651 4.8657 2.8783 16.4165
D-423MG GDSC1 3.2171 5.7778 2.5483 18.5428
Onda 10 GDSC1 3.2465 5.4163 2.7383 17.0123
SW1088 GDSC1 3.3685 7.1407 2.0561 21.2997
MOG-G-UVW GDSC1 3.4662 5.0114 3.139 12.9767
42-MG-BA GDSC1 3.4924 5.8742 2.7794 15.5267
ONS-76 GDSC1 3.5284 7.062 2.2451 19.273
KNS-81-FD GDSC1 3.5461 5.1787 3.1501 12.498
T98G GDSC1 3.5609 5.3732 3.0785 12.9609
A-172 GDSC1 3.6254 9.9241 0.9211 26.755
SF295 GDSC1 3.6587 4.3848 3.58 8.8118
U-118MG GDSC1 3.7062 4.3968 3.6281 8.2149
SF268 GDSC1 3.7447 5.6943 3.1106 11.8696
KINGS-1 GDSC1 3.8251 5.7329 3.1692 11.0644
Becker GDSC1 4.0984 10.0239 1.2826 22.9572
Onda 11 GDSC1 4.1814 8.7493 1.99 18.3198
KALS-1 GDSC1 4.2379 6.8978 2.9633 11.0011
DBTRG-05MG GDSC1 4.263 10.1952 1.3361 22.0261
NMC-G1 GDSC1 4.5068 9.989 1.6409 19.3328
KNS-42 GDSC1 7.7331 14.1183 1.8899 9.0771
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 1.358 5.2554 0.7917 39.6097
ETK-1 GDSC1 1.6644 3.4119 1.61 33.5533
TGBC1TKB GDSC1 2.9455 3.5718 2.941 17.2338
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC1 -1.2873 2.4847 -1.4134 66.1564
KLE GDSC1 0.2587 3.636 0.0543 50.6816
MFE-280 GDSC1 0.2872 4.2931 -0.0735 50.3474
MFE-319 GDSC1 1.7986 3.9194 1.6667 32.3533
MFE-296 GDSC1 2.5253 3.7881 2.477 22.7657
EN GDSC1 3.2034 6.586 2.1618 21.3538
ESS-1 GDSC1 3.2885 4.508 3.1384 13.9191
AN3-CA GDSC1 5.8783 15.1856 0.1263 22.5872
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
769-P GDSC1 -0.0696 4.2728 -0.4573 53.7463
KTCTL-140 GDSC1 0.2897 4.8132 -0.2219 50.3018
SW13 GDSC1 0.3473 3.4963 0.1786 49.7198
RCC10RGB GDSC1 0.6071 3.3811 0.4805 46.7251
A-704 GDSC1 0.9808 3.152 0.9157 42.0673
KTCTL-21 GDSC1 1.0189 4.8034 0.5751 42.8752
TK-10 GDSC1 1.0838 4.0115 0.8678 41.4206
KTCTL-26A GDSC1 1.2834 4.0906 1.066 39.0727
LB996-RCC GDSC1 1.3324 7.5813 -0.1751 42.3911
ACHN GDSC1 1.3864 7.4547 -0.0642 41.8194
KTCTL-13 GDSC1 1.4844 4.1303 1.2754 36.6259
LB1047-RCC GDSC1 1.5781 4.6352 1.2364 36.171
HA7-RCC GDSC1 1.6163 5.3863 1.0228 36.8902
CAL-54 GDSC1 1.6388 4.2696 1.4078 34.8769
LB2241-RCC GDSC1 1.7643 4.0268 1.6054 32.9362
VMRC-RCZ GDSC1 1.7784 3.6247 1.7007 32.275
KTCTL-195 GDSC1 1.8588 3.2749 1.8312 30.9617
786-O GDSC1 1.8599 3.6668 1.7814 31.2658
SN12C GDSC1 1.8899 4.4309 1.6373 31.9484
UO-31 GDSC1 1.9472 4.4568 1.6923 31.2626
NCC021 GDSC1 1.9489 3.6417 1.8812 30.0886
KTCTL-1M GDSC1 2.0844 4.6892 1.7707 29.9443
SW156 GDSC1 2.4891 4.1794 2.3588 23.7562
BB65-RCC GDSC1 2.5068 4.8942 2.1598 24.9848
OS-RC-2 GDSC1 2.5629 4.2474 2.4221 22.9057
KMRC-1 GDSC1 2.6937 3.7861 2.6575 20.5829
VMRC-RCW GDSC1 2.7245 3.6392 2.7069 20.0786
KMRC-20 GDSC1 2.9421 4.8231 2.6547 19.1895
BFTC-909 GDSC1 3.4342 4.3549 3.3439 11.6909
RXF 393L GDSC1 3.8295 6.8665 2.6191 15.251
A-498 GDSC1 4.3004 5.2049 3.8623 3.7035
Caki-1 GDSC1 4.8005 15.2228 -0.735 29.006
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CCK-81 GDSC1 -1.7012 1.6222 -1.7566 71.1099
HT115 GDSC1 0.38 3.4478 0.2232 49.3526
SW1116 GDSC1 0.5812 6.2481 -0.4105 47.8937
SNU-175 GDSC1 1.0348 5.3823 0.3979 43.2037
NCI-H747 GDSC1 1.1382 5.4261 0.4938 42.1707
SNU-1040 GDSC1 1.9171 5.9425 1.1282 34.4618
SNU-61 GDSC1 1.9311 6.0873 1.0838 34.5807
SNU-C2B GDSC1 1.9545 7.4554 0.5153 36.7266
LoVo GDSC1 1.993 4.8927 1.6043 31.4964
C2BBe1 GDSC1 2.1518 4.6841 1.8456 29.0762
GP5d GDSC1 2.2828 6.3791 1.3269 31.288
CaR-1 GDSC1 2.2829 4.5632 2.0264 27.1485
SNU-81 GDSC1 2.2949 11.4074 -1.0252 39.1144
CL-11 GDSC1 2.3911 3.7589 2.3374 24.4778
HT-55 GDSC1 2.4222 7.9652 0.748 33.2242
RKO GDSC1 2.4654 3.9285 2.3881 23.7025
SW1417 GDSC1 2.8182 11.1842 -0.4309 35.3695
COLO205 GDSC1 2.8432 5.1026 2.4437 21.1999
LS411N GDSC1 2.9795 6.534 1.9649 23.7726
SW837 GDSC1 2.9825 7.3543 1.5833 26.1346
LS180 GDSC1 3.0369 9.6978 0.5001 31.217
SW626 GDSC1 3.1701 4.6595 2.9588 15.8204
SW48 GDSC1 3.2419 7.5857 1.7211 24.0547
NCI-H716 GDSC1 3.3939 4.9077 3.1054 13.5904
COLO 678 GDSC1 3.4734 4.484 3.3471 11.4498
SNU-C5 GDSC1 3.5118 5.3918 3.0204 13.6303
HCT 116 GDSC1 3.5131 5.2776 3.0727 13.2345
HT-29 GDSC1 3.6538 8.7691 1.5196 23.424
LS513 GDSC1 3.7998 7.882 2.09 19.1781
RCM-1 [Human ESC] GDSC1 4.21 10.2432 1.2675 22.6097
COLO 320HSR GDSC1 4.266 7.9118 2.4802 14.557
HCT 15 GDSC1 4.2887 6.8521 3.029 10.302
T84 GDSC1 4.3804 7.1421 2.9602 10.5035
SNU-407 GDSC1 4.4833 11.9874 0.6228 24.8506
SW620 GDSC1 4.5126 6.9028 3.1868 8.2781
KM12 GDSC1 4.7409 8.8711 2.3864 13.5483
LS123 GDSC1 4.7854 11.1693 1.2764 20.4714
HCC2998 GDSC1 5.0374 9.5805 2.2625 13.4491
SNU-C1 GDSC1 5.0925 12.1475 1.0313 20.7601
LS1034 GDSC1 5.642 9.3842 2.7883 7.9774
SW948 GDSC1 5.6572 7.377 3.7114 1.6324
MDST8 GDSC1 5.677 7.2686 3.7661 1.297
SW1463 GDSC1 5.7591 17.2522 -0.988 26.9897
CW-2 GDSC1 6.1278 15.6634 0.0768 22.0939
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 2.5986 3.8012 2.5535 21.8294
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-4 GDSC1 -2.3332 0.7798 -2.3588 77.5557
JHH-1 GDSC1 -0.5439 24.3467 -9.9872 51.8902
JHH-2 GDSC1 -0.4723 1.823 -0.4934 59.4671
SNU-423 GDSC1 0.087 3.2975 -0.0658 52.5782
SNU-449 GDSC1 0.7155 3.8871 0.4958 45.6655
SNU-398 GDSC1 1.0683 3.1423 1.01 40.9632
JHH-7 GDSC1 1.3094 2.3153 1.3081 37.6645
Huh-7 GDSC1 1.5918 3.117 1.5651 34.291
Hep 3B2.1-7 GDSC1 1.6173 4.6984 1.2595 35.7893
HLE GDSC1 1.6343 2.9246 1.6224 33.669
JHH-6 GDSC1 1.6905 2.3216 1.6905 32.8929
SNU-387 GDSC1 1.9319 7.6884 0.3872 37.2942
SNU-475 GDSC1 2.2256 3.3398 2.2096 26.305
SK-HEP-1 GDSC1 3.249 3.982 3.2232 13.5759
Hep-G2/C3A GDSC1 3.7105 5.0984 3.3535 10.1854
HuH-1 GDSC1 3.7926 4.2782 3.7556 6.8572
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 172 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Calu-3 GDSC1 -4.592 6.8285 -6.1899 71.1786
NCI-H1623 GDSC1 -2.9701 2.3701 -3.2007 75.6715
NCI-H3255 GDSC1 -2.4373 3.4352 -2.8328 70.7593
HCC827 GDSC1 -1.5844 9.7713 -4.1342 58.7019
NCI-H1781 GDSC1 -1.554 2.7023 -1.7321 67.6091
COR-L105 GDSC1 -1.1758 6.2972 -2.3133 59.78
PaCa-3 GDSC1 -0.9632 4.9626 -1.6328 60.0074
NCI-H1568 GDSC1 -0.4516 4.6847 -0.991 56.6784
NCI-H1648 GDSC1 -0.285 3.6886 -0.548 56.0686
NCI-H322M GDSC1 -0.0833 4.6495 -0.579 53.6922
NCI-H1975 GDSC1 0.215 2.4769 0.1776 51.2824
CAL-12T GDSC1 0.6126 3.5154 0.4621 46.7046
EPLC-272H GDSC1 0.7143 2.487 0.6961 45.166
EKVX GDSC1 0.7445 4.176 0.4566 45.4827
NCI-H1869 GDSC1 0.7625 5.9652 -0.1088 46.2149
NCI-H1666 GDSC1 0.7711 4.9985 0.243 45.6411
NCI-H1341 GDSC1 0.7971 4.4986 0.4255 45.0822
PC-14 GDSC1 0.9179 5.1974 0.3358 44.2621
LCLC-97TM1 GDSC1 1.1416 3.3308 1.0629 40.1571
NCI-H2342 GDSC1 1.1874 6.9112 -0.0377 43.0528
NCI-H661 GDSC1 1.2101 7.1838 -0.1294 43.082
NCI-H358 GDSC1 1.3323 4.2696 1.0734 38.6778
NCI-H1435 GDSC1 1.3797 2.9102 1.3596 36.8987
HCC78 GDSC1 1.4282 3.7987 1.2899 36.9454
NCI-H2795 GDSC1 1.4463 4.3648 1.1719 37.402
SW1271 GDSC1 1.4484 4.5682 1.1154 37.6486
NCI-H2087 GDSC1 1.4539 4.1265 1.2431 37.0027
NCI-H1304 GDSC1 1.4862 2.7453 1.4781 35.4961
NCI-H2810 GDSC1 1.6411 3.6076 1.5558 34.0265
NCI-H2066 GDSC1 1.6594 4.6185 1.3301 35.1482
NCI-H510A GDSC1 1.8167 3.279 1.7865 31.5044
Lu-135 GDSC1 1.8512 4.1025 1.6822 31.9259
Ms-1 GDSC1 1.8583 3.4608 1.8102 31.0966
IST-SL2 GDSC1 1.912 3.4743 1.8656 30.4152
NCI-H1436 GDSC1 1.937 3.2138 1.9181 29.9299
NCI-H847 GDSC1 1.954 3.4806 1.9094 29.8799
NCI-H524 GDSC1 1.9779 3.771 1.8904 29.8516
UMC-11 GDSC1 2.0182 3.5711 1.9659 29.1262
NCI-H1581 GDSC1 2.0347 4.3339 1.8226 29.9274
NCI-H1838 GDSC1 2.0419 6.1297 1.1824 33.4367
NCI-H69 GDSC1 2.0448 4.9314 1.6472 30.9271
NCI-H596 GDSC1 2.0552 3.7475 1.978 28.8234
IST-SL1 GDSC1 2.0838 3.4838 2.0469 28.2096
Calu-6 GDSC1 2.1224 4.062 1.9872 28.3563
NCI-H2291 GDSC1 2.127 4.4273 1.8969 28.9025
NCI-H2030 GDSC1 2.1353 3.7866 2.0576 27.8268
HOP-62 GDSC1 2.1546 3.9537 2.0461 27.7837
NCI-H211 GDSC1 2.1564 3.9394 2.051 27.742
NCI-H2347 GDSC1 2.1722 4.0101 2.053 27.6336
NCI-H1876 GDSC1 2.2102 3.6922 2.1537 26.7559
NCI-H1770 GDSC1 2.2318 4.3819 2.0242 27.4635
NCI-H2171 GDSC1 2.2374 3.8636 2.1538 26.5911
NCI-H1792 GDSC1 2.252 3.6827 2.1999 26.2054
NCI-H23 GDSC1 2.2917 3.5886 2.255 25.6104
LC-2/ad GDSC1 2.3444 4.1016 2.2198 25.5227
NCI-H720 GDSC1 2.3468 3.8572 2.2732 25.1603
LB647-SCLC GDSC1 2.3775 3.7459 2.3249 24.6412
NCI-H1694 GDSC1 2.3925 3.9238 2.31 24.6473
NCI-H2444 GDSC1 2.395 4.9854 2.0066 26.6281
NCI-H2029 GDSC1 2.4051 3.6638 2.3661 24.2086
NCI-H522 GDSC1 2.4142 4.4765 2.1957 25.2736
NCI-H1105 GDSC1 2.4423 3.857 2.3764 23.9171
NCI-H2196 GDSC1 2.4588 4.7368 2.1619 25.242
NCI-H1944 GDSC1 2.4633 4.0134 2.3687 23.8424
NCI-H1048 GDSC1 2.485 4.3216 2.3173 24.0557
NCI-H2141 GDSC1 2.5379 4.0958 2.4317 22.9872
NCI-H1573 GDSC1 2.5413 4.9338 2.1829 24.6365
RERF-LC-Sq1 GDSC1 2.545 5.0859 2.1312 24.9617
NCI-H2110 GDSC1 2.5636 4.3454 2.3966 23.0717
SBC-3 GDSC1 2.5756 3.7094 2.5417 22.0446
LK-2 GDSC1 2.576 3.6993 2.5435 22.0303
NCI-H2818 GDSC1 2.5857 4.0418 2.4956 22.2842
NCI-H727 GDSC1 2.5872 4.0989 2.4847 22.3476
NCI-H1915 GDSC1 2.595 3.8234 2.5463 21.8977
NCI-H650 GDSC1 2.6154 4.0256 2.5313 21.8739
NCI-H2081 GDSC1 2.623 3.8307 2.5751 21.5425
ABC-1 GDSC1 2.6255 4.214 2.4989 22.0295
NCI-H1563 GDSC1 2.6439 4.2409 2.5121 21.835
COR-L303 GDSC1 2.6546 3.4635 2.6467 20.8912
EMC-BAC-1 GDSC1 2.6714 12.4459 -1.186 37.8512
LOU-NH91 GDSC1 2.689 4.0319 2.6098 20.9224
NCI-H290 GDSC1 2.6907 3.8825 2.6396 20.7169
NCI-H441 GDSC1 2.7089 4.0868 2.6197 20.7396
EMC-BAC-2 GDSC1 2.7136 5.9171 1.9715 25.1005
NCI-H1734 GDSC1 2.7144 3.7415 2.6853 20.2785
NCI-H2228 GDSC1 2.7198 3.8738 2.6723 20.3302
NCI-H146 GDSC1 2.7198 4.5739 2.4987 21.4934
CPC-N GDSC1 2.7468 4.8502 2.4344 21.7853
NCI-H2461 GDSC1 2.7665 4.2821 2.6352 20.3019
SK-LU-1 GDSC1 2.7769 4.7442 2.5042 21.1382
NCI-H835 GDSC1 2.7783 4.343 2.6315 20.2588
NCI-H446 GDSC1 2.7974 3.8076 2.7652 19.2613
NCI-H226 GDSC1 2.8027 3.533 2.7959 19.0326
NCI-H64 GDSC1 2.8164 4.2388 2.7009 19.5729
NCI-H2135 GDSC1 2.8291 4.4329 2.6612 19.7684
NCI-H1155 GDSC1 2.844 4.2924 2.717 19.3059
NCI-H647 GDSC1 2.8663 4.1424 2.7786 18.7641
Lu-65 GDSC1 2.8892 4.5405 2.6936 19.2097
NCI-H1355 GDSC1 2.9041 5.0902 2.5134 20.3861
A-427 GDSC1 2.9492 4.9805 2.6038 19.5094
NCI-H2804 GDSC1 2.9679 4.4318 2.8128 17.9502
COLO 668 GDSC1 2.9762 4.6441 2.7542 18.3092
NCI-H1688 GDSC1 2.9874 4.2552 2.8832 17.3625
NCI-H2591 GDSC1 2.9919 4.3722 2.8563 17.5182
NCI-H2869 GDSC1 2.9972 4.487 2.828 17.682
NCI-H2722 GDSC1 2.9985 4.5826 2.7989 17.8755
LCLC-103H GDSC1 3.0118 4.6517 2.7902 17.8631
NCI-H1651 GDSC1 3.0139 4.604 2.8085 17.7242
NCI-H520 GDSC1 3.0149 3.8322 2.9934 16.4743
NCI-H1993 GDSC1 3.055 5.1304 2.6576 18.5702
NCI-H810 GDSC1 3.0738 4.0505 3.0231 15.9278
HCC33 GDSC1 3.1272 4.8005 2.8619 16.7347
NCI-H2731 GDSC1 3.1759 4.4626 3.0302 15.2926
SHP-77 GDSC1 3.1843 4.2437 3.1008 14.7648
NCI-H1703 GDSC1 3.1863 5.0048 2.8468 16.5303
LXF 289 GDSC1 3.2089 4.9031 2.9107 15.9542
NCI-H1836 GDSC1 3.2194 4.7518 2.979 15.4128
NCI-H196 GDSC1 3.2687 4.2995 3.1785 13.7559
SBC-5 GDSC1 3.3195 4.3689 3.2147 13.2212
HCC15 GDSC1 3.337 4.8025 3.086 14.0267
Lu-139 GDSC1 3.3607 6.9894 2.1217 20.8895
NCI-H1755 GDSC1 3.367 4.5488 3.21 12.9892
COR-L88 GDSC1 3.4007 4.9539 3.094 13.6382
NCI-H2369 GDSC1 3.4272 4.87 3.1557 13.0549
NCI-H187 GDSC1 3.4457 5.0335 3.1083 13.3049
IA-LM GDSC1 3.5089 4.4184 3.4065 10.8421
DMS 114 GDSC1 3.5091 6.564 2.4679 17.7606
HARA [Human squamous cell lung carcinoma] GDSC1 3.5127 10.3625 0.6034 28.6956
RERF-LC-MS GDSC1 3.532 8.3809 1.6016 23.4653
NCI-H1793 GDSC1 3.5497 11.5973 0.0223 30.8563
NCI-H3122 GDSC1 3.5581 5.61 2.9672 13.8103
NCI-H2595 GDSC1 3.5755 5.6876 2.9484 13.8716
NCI-H82 GDSC1 3.5825 4.4923 3.4628 10.045
NCI-H2803 GDSC1 3.5845 4.503 3.4614 10.0438
NCI-H2009 GDSC1 3.5873 7.3099 2.1789 19.476
NCI-H460 GDSC1 3.591 4.1046 3.5713 9.2625
Lu-99A GDSC1 3.6126 7.8361 1.9436 20.9587
COR-L321 GDSC1 3.6228 5.6563 3.0097 13.1902
SK-MES-1 GDSC1 3.6303 4.9315 3.3438 10.6504
A-549 GDSC1 3.6394 4.5176 3.5158 9.3634
HCC44 GDSC1 3.6424 5.8762 2.9251 13.7429
NCI-H2405 GDSC1 3.6634 7.3049 2.2514 18.6365
NCI-H2170 GDSC1 3.7021 10.5239 0.6904 27.5225
NCI-H1650 GDSC1 3.7112 5.2119 3.303 10.5605
KNS-62 GDSC1 3.7271 4.2603 3.6885 7.6864
SBC-1 GDSC1 3.743 6.0943 2.9167 13.3607
NCI-H526 GDSC1 3.775 4.5041 3.667 7.5661
Lu-134-A GDSC1 3.8122 5.7128 3.1665 11.1411
NCI-H1092 GDSC1 3.8956 6.6255 2.7981 13.6218
Lu-165 GDSC1 3.9585 4.5941 3.8281 5.4485
RERF-LC-KJ GDSC1 4.012 6.7002 2.8656 12.6312
ChaGo-K-1 GDSC1 4.0214 6.6796 2.8841 12.4509
SW1573 GDSC1 4.0565 7.1457 2.6832 13.8469
NCI-H2373 GDSC1 4.0612 8.4073 2.0581 18.3323
EBC-1 GDSC1 4.0817 6.8613 2.8469 12.4993
BEN GDSC1 4.2742 7.7095 2.5882 13.727
COR-L23 GDSC1 4.3329 7.877 2.5535 13.7671
COR-L311 GDSC1 4.4521 7.6921 2.7441 11.9065
NCI-H513 GDSC1 4.4823 10.0553 1.5878 19.7441
NCI-H1437 GDSC1 4.7736 6.5845 3.5414 4.6997
DMS 53 GDSC1 4.8087 7.8812 2.9299 9.2964
NCI-H345 GDSC1 4.8602 8.5876 2.6194 11.4616
NCI-H292 GDSC1 4.9811 11.8331 1.1005 20.7635
NCI-H841 GDSC1 5.0109 7.7209 3.1568 6.9607
NCI-H209 GDSC1 5.1793 8.7237 2.7882 9.2391
NCI-H1299 GDSC1 5.7792 11.8781 1.6787 14.9927
NCI-H2122 GDSC1 5.7886 9.9543 2.6143 8.8299
COR-L95 GDSC1 5.7932 9.7442 2.717 8.0997
NCI-H838 GDSC1 5.9211 8.7055 3.2758 3.9408
NCI-H2023 GDSC1 6.3396 11.0374 2.4598 8.5398
NCI-H2172 GDSC1 6.4315 7.8981 3.8453 0.3465
DMS 273 GDSC1 6.9453 8.4633 3.8353 0.1916
⏷ Show the Full List of 172 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 2.1114 4.4541 1.8721 29.1529
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OE19 GDSC1 -4.3667 5.6634 -5.5578 72.5186
TE-4 GDSC1 -3.2509 2.8252 -3.5872 75.4334
TE-15 GDSC1 -2.0538 13.8556 -6.426 57.9345
KYSE-450 GDSC1 -1.0913 2.8082 -1.2519 64.0488
TE-6 GDSC1 -0.2244 5.1296 -0.8816 54.6025
KYSE-520 GDSC1 0.444 3.5119 0.2802 48.6393
EC-GI-10 GDSC1 0.4554 4.8123 -0.0411 48.7231
KYSE-270 GDSC1 0.7553 4.7643 0.3003 45.6787
KYSE-140 GDSC1 0.8471 3.1011 0.78 43.7064
TE-10 GDSC1 0.9565 3.4589 0.8436 42.5496
TE-5 GDSC1 0.9918 2.695 0.971 41.7342
KYSE-150 GDSC1 1.1964 4.1215 0.9635 40.1663
COLO 680N GDSC1 1.6044 2.9958 1.5873 34.0744
TE-9 GDSC1 1.7608 4.7725 1.392 34.153
TE-1 GDSC1 2.1358 3.3634 2.1139 27.4641
KYSE-70 GDSC1 2.2069 3.1481 2.2008 26.4755
OE33 GDSC1 2.3065 6.2082 1.425 30.6288
T.T GDSC1 2.3337 4.3726 2.1381 26.122
KYSE-180 GDSC1 2.3632 4.5243 2.1258 26.0307
TE-8 GDSC1 2.4246 6.2874 1.5129 29.4732
KYSE-410 GDSC1 2.476 6.1161 1.6401 28.4524
OE21 GDSC1 2.5189 4.1734 2.3927 23.3569
TE-11 GDSC1 2.697 4.1141 2.6007 20.9358
KYSE-510 GDSC1 5.2752 9.9628 2.2512 12.7882
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TOV-112D GDSC1 0.3886 3.8079 0.158 49.2847
JHOS-4 GDSC1 0.5125 3.2685 0.3976 47.807
Kuramochi GDSC1 0.9013 5.4551 0.2279 44.6092
Caov-3 GDSC1 1.3022 3.9209 1.1267 38.6574
OAW28 GDSC1 1.3428 4.3912 1.0515 38.6961
RMG-I GDSC1 1.525 7.5165 0.0508 40.6904
OVCAR-4 GDSC1 1.7424 4.3129 1.5092 33.6326
JHOS-2 GDSC1 1.8955 4.547 1.6092 32.0771
OVCAR-8 GDSC1 2.1352 3.5447 2.0941 27.5937
FU-OV-1 GDSC1 2.1574 3.407 2.1326 27.2129
IGROV-1 GDSC1 2.1914 4.0555 2.0638 27.4488
A2780 GDSC1 2.2619 4.1892 2.1086 26.7376
EFO-21 GDSC1 2.4407 4.7743 2.1297 25.559
TYK-nu GDSC1 2.4686 4.4074 2.2753 24.4304
DOV13 GDSC1 2.4747 4.4386 2.273 24.4104
Caov-4 GDSC1 2.5063 4.107 2.3947 23.4177
OC 314 GDSC1 2.6196 3.1639 2.6191 21.282
ES-2 GDSC1 2.6598 3.3156 2.6575 20.7911
EFO-27 GDSC1 2.7842 10.4237 -0.0892 34.4937
OVCAR-3 GDSC1 2.9775 8.1503 1.1975 28.2927
OV56 GDSC1 3.0248 3.6571 3.0185 16.2537
SK-OV-3 GDSC1 3.0918 6.3122 2.1791 21.7755
OVCAR-5 GDSC1 3.0935 4.8692 2.8003 17.3509
OVK18 GDSC1 3.2519 6.7618 2.126 21.3682
OVISE GDSC1 3.5455 10.5838 0.5226 28.907
OVKATE GDSC1 3.9024 4.5206 3.7978 5.9578
TOV-21G GDSC1 3.9416 7.1224 2.5933 14.9823
OAW42 GDSC1 4.026 8.3967 2.033 18.6415
OVTOKO GDSC1 4.382 8.7042 2.1807 16.2659
OV-90 GDSC1 4.8421 8.8312 2.4848 12.5043
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuP-T4 GDSC1 0.888 3.6991 0.7242 43.5358
Capan-1 GDSC1 1.1414 3.7661 0.9854 40.5015
Panc 03.27 GDSC1 1.844 4.363 1.6064 32.4201
HPAC GDSC1 1.949 10.7542 -1.0362 40.7164
MZ-PC-1 GDSC1 2.0392 4.8337 1.6743 30.801
HPAF-II GDSC1 2.2781 6.8822 1.1006 32.4439
Capan-2 GDSC1 2.3185 4.0099 2.2122 25.7262
HuP-T3 GDSC1 2.3556 7.5382 0.8806 33.0167
SUIT-2 GDSC1 2.3689 6.5299 1.3495 30.6788
Panc 04.03 GDSC1 2.4102 6.2585 1.5105 29.5673
BxPC-3 GDSC1 2.4529 6.721 1.3503 30.2068
MIA PaCa-2 GDSC1 2.6927 3.3511 2.6901 20.3817
Panc 08.13 GDSC1 2.9144 4.7522 2.65 19.3726
KP-4 GDSC1 3.1368 4.5116 2.9722 15.9097
Hs 766T GDSC1 3.16 5.2032 2.7386 17.446
PL4 GDSC1 3.2798 5.7228 2.6366 17.5932
SU.86.86 GDSC1 3.3903 4.3436 3.2992 12.245
PaTu 8902 GDSC1 3.5926 4.4732 3.4801 9.8688
KP-1N GDSC1 3.6302 5.4198 3.1268 12.2704
CFPAC-1 GDSC1 3.6416 7.1814 2.292 18.4433
PaTu 8988t GDSC1 3.8928 5.5782 3.3082 9.6973
Panc 02.03 GDSC1 4.0795 12.2032 0.1775 28.2265
QGP-1 GDSC1 4.1677 7.2 2.7524 12.8899
PSN1 GDSC1 4.3239 5.4428 3.7631 4.4004
YAPC GDSC1 4.5577 10.6609 1.3467 20.8792
AsPC-1 GDSC1 4.7577 10.0711 1.8019 17.4421
KP-3 GDSC1 5.108 9.8059 2.2043 13.6257
DAN-G GDSC1 5.6074 9.0754 2.9122 7.1786
SW1990 GDSC1 5.6853 11.5824 1.7557 14.7946
Panc 10.05 GDSC1 9.4673 20.5574 -0.0137 14.936
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1 2.1727 3.0883 2.1679 26.8957
NCI-H28 GDSC1 2.3984 5.324 1.8839 27.3963
IST-Mes1 GDSC1 2.5618 3.6667 2.5324 22.1879
NCI-H2452 GDSC1 3.3414 5.646 2.7335 16.5823
NCI-H2052 GDSC1 3.3834 4.0939 3.3497 11.9474
MSTO-211H GDSC1 3.3917 8.6664 1.3329 25.6352
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 2.4202 4.2708 2.2603 24.8108
22Rv1 GDSC1 2.6513 4.3051 2.5033 21.8516
VCaP GDSC1 2.7442 4.8938 2.4159 21.9277
DU145 GDSC1 2.7926 4.8224 2.4937 21.125
LNCaP clone FGC GDSC1 4.072 5.9985 3.2672 9.2684
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 0.0555 2.5243 0.0061 53.1451
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-431 GDSC1 -3.4839 -0.6886 -3.4894 87.7518
CHL-1 GDSC1 -2.6848 1.26 -2.7559 77.8371
IGR-1 GDSC1 -1.5757 -0.5077 -1.5757 73.6405
WM278 GDSC1 -1.1456 2.0353 -1.2104 65.8526
A-375 GDSC1 -1.0805 2.2529 -1.1643 64.915
HT-144 GDSC1 -0.8787 0.0241 -0.8787 65.0016
SK-MEL-28 GDSC1 -0.6695 0.1557 -0.6695 62.3915
Hs 940.T GDSC1 -0.5809 2.4374 -0.6562 60.0496
WM793 GDSC1 -0.5686 0.2416 -0.5686 61.1302
WM1552C GDSC1 -0.4034 1.1196 -0.4049 58.999
G-mel GDSC1 -0.1811 0.4169 -0.1811 56.2883
IGR-37 GDSC1 -0.1389 0.2392 -0.1389 55.7607
MMAc-SF GDSC1 -0.1343 1.2474 -0.1353 55.6811
IPC-298 GDSC1 -0.0286 1.0713 -0.0287 54.378
CP50-MEL-B GDSC1 0.3188 3.8961 0.0617 50.0326
SK-MEL-30 GDSC1 0.5121 1.9446 0.5083 47.6338
LOX-IMVI GDSC1 0.6623 6.1096 -0.2708 47.1612
SK-MEL-2 GDSC1 0.681 8.745 -1.3553 47.772
SH-4 GDSC1 0.6892 1.5289 0.6892 45.4092
HMV-II GDSC1 0.7229 1.653 0.7227 44.9887
Hs 938.T GDSC1 0.7408 1.2211 0.7408 44.7646
G-361 GDSC1 0.8455 4.8863 0.3601 44.8032
A-388 GDSC1 0.8458 3.5552 0.7067 43.9572
RPMI-7951 GDSC1 0.8674 6.0573 -0.0318 45.3105
DJM-1 GDSC1 1.3288 4.5064 1.0033 39.0043
451Lu GDSC1 1.3895 2.5619 1.3851 36.6828
MZ-MEL-7 GDSC1 1.3932 4.6209 1.0394 38.3804
Mel JuSo GDSC1 1.3934 2.3422 1.3924 36.6124
SK-MEL-5 GDSC1 1.4573 3.8466 1.3114 36.6299
LB2518-MEL GDSC1 1.5603 4.6303 1.2185 36.3803
COLO 792 GDSC1 1.72 2.5742 1.719 32.5304
UACC-62 GDSC1 1.8091 2.2078 1.8091 31.41
COLO 800 GDSC1 1.8845 3.3726 1.8485 30.6934
RVH-421 GDSC1 2.0971 6.948 0.8869 34.4507
IST-MEL1 GDSC1 2.3723 4.4314 2.1634 25.7304
A2058 GDSC1 2.5815 6.3789 1.6336 27.9118
SK-MEL-24 GDSC1 2.6393 4.2718 2.4991 21.9482
CP66-MEL GDSC1 2.8928 3.5441 2.8881 17.8939
WM35 GDSC1 2.9323 8.1273 1.1655 28.6776
VMRC-MELG GDSC1 2.9413 12.0426 -0.7418 35.6949
MZ-MEL-2 GDSC1 3.0584 5.6084 2.461 19.9594
M14 GDSC1 3.3358 7.7267 1.7412 23.4946
WM115 GDSC1 3.5137 9.0031 1.2778 25.3964
Mel Ho GDSC1 3.5641 4.4209 3.4659 10.1246
SK-MEL-3 GDSC1 3.5846 4.0903 3.5666 9.3313
GAK GDSC1 3.614 5.412 3.1141 12.4416
COLO 829 GDSC1 3.6226 4.4537 3.519 9.4332
A101D GDSC1 3.6444 4.1228 3.6258 8.5881
LB373-MEL-D GDSC1 3.6446 11.8082 0.0004 30.5595
SK-MEL-1 GDSC1 3.6691 4.2437 3.6292 8.4188
MeWo GDSC1 3.6762 4.1603 3.6539 8.2145
COLO 783 GDSC1 3.7072 6.7903 2.5443 16.3262
COLO 679 GDSC1 3.7488 4.4955 3.6418 7.8855
UACC-257 GDSC1 3.8166 4.1815 3.8015 6.413
WT2-iPS GDSC1 4.1871 7.3957 2.6713 13.4315
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 3.8849 7.8249 2.1941 18.1068
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 633.T GDSC1 -3.5062 -0.5066 -3.515 87.1187
SK-UT-1 GDSC1 -0.4089 0.788 -0.4091 59.1199
Rh41 GDSC1 0.0076 6.6683 -1.1847 52.2706
Rh30 GDSC1 1.4049 3.269 1.3521 36.7719
KYM-1 GDSC1 2.3519 5.2362 1.8679 27.7625
G-401 GDSC1 2.3676 4.4141 2.1633 25.7583
Rh18 GDSC1 2.3846 3.7548 2.3311 24.558
G-402 GDSC1 2.443 3.7466 2.395 23.7921
SK-LMS-1 GDSC1 2.5063 4.4994 2.2893 24.1203
MFH-ino GDSC1 2.5508 3.873 2.4905 22.5254
HT-1080 GDSC1 3.0159 4.0645 2.9577 16.7001
SW872 GDSC1 3.5751 7.7559 1.9487 21.0896
SW684 GDSC1 3.6454 4.1717 3.6185 8.6293
EW-8 GDSC1 3.7036 4.8053 3.4734 9.3314
VA-ES-BJ GDSC1 3.8197 4.2886 3.7825 6.5206
RKN GDSC1 3.8631 4.2788 3.8323 5.936
MES-SA GDSC1 4.0341 5.5375 3.4603 7.9153
GCT GDSC1 4.2519 11.6058 0.6215 25.6972
SW982 GDSC1 4.9108 15.4946 -0.7816 28.8107
A-204 GDSC1 7.2033 17.3075 0.0454 19.4556
RD GDSC1 7.5042 17.588 0.117 18.4453
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-N87 GDSC1 -2.8848 15.5514 -8.0342 59.2711
AGS GDSC1 -1.4994 -0.3759 -1.4994 72.6767
GCIY GDSC1 -0.6336 4.0944 -1.0258 58.657
NUGC-4 GDSC1 -0.2237 6.1265 -1.2267 54.0793
MKN1 GDSC1 -0.083 2.7276 -0.1622 54.6302
SNU-1 GDSC1 0.3115 2.0451 0.3018 50.1284
HSC-39 GDSC1 0.396 1.3634 0.3958 49.0749
NUGC-3 GDSC1 0.669 1.7897 0.6682 45.6652
RERF-GC-1B GDSC1 1.1104 5.3282 0.4986 42.3682
ECC10 GDSC1 1.4386 3.5818 1.342 36.5959
KATO III GDSC1 1.8355 3.7617 1.7383 31.6847
MKN7 GDSC1 1.8523 2.8685 1.8479 30.8981
Hs 746.T GDSC1 2.1345 4.153 1.9787 28.3371
TGBC11TKB GDSC1 2.1474 3.867 2.0558 27.7649
23132/87 GDSC1 2.6257 4.8052 2.3195 23.2421
Fu97 GDSC1 2.7695 5.0011 2.4035 21.8756
SCH GDSC1 3.3599 7.8941 1.6821 23.7485
IM95 GDSC1 3.5335 13.9555 -1.1667 34.5063
HGC-27 GDSC1 3.5545 4.6367 3.3814 10.7693
RF-48 GDSC1 3.854 4.6247 3.7056 6.874
MKN28 GDSC1 3.9042 9.3577 1.448 22.7966
MKN45 GDSC1 4.5657 5.7173 3.8155 3.1934
SNU-16 GDSC1 4.8086 6.2057 3.7483 3.0357
OCUM-1 GDSC1 4.8604 6.602 3.5934 4.0629
SNU-5 GDSC1 6.3167 7.4798 3.9489 0.1511
SNG-M GDSC1 -0.0077 2.3634 -0.046 53.9194
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1 -1.8075 0.509 -1.8138 74.5927
IHH-4 GDSC1 -0.4617 1.4766 -0.4694 59.5597
B-CPAP GDSC1 0.0227 3.5635 -0.1868 53.1613
TT2609-C02 GDSC1 0.1299 2.0944 0.1136 52.3461
8505C GDSC1 0.4386 2.9782 0.3609 48.6307
K5 GDSC1 0.5712 1.7106 0.5704 46.8873
ML-1 [Human leukemia] GDSC1 1.3134 3.8612 1.152 38.4561
BHT-101 GDSC1 1.4303 3.4246 1.3582 36.5641
HTC-C3 GDSC1 1.5141 11.5701 -1.8441 43.9018
CAL-62 GDSC1 2.012 4.1882 1.8362 29.9822
8305C GDSC1 2.1651 3.7812 2.0907 27.434
CGTH-W-1 GDSC1 2.8372 3.4356 2.8348 18.5742
ASH-3 GDSC1 2.8886 4.1071 2.8106 18.4213
FTC-133 GDSC1 3.344 4.3348 3.2512 12.8341
WRO GDSC1 3.675 4.2673 3.63 8.3796
TT GDSC1 6.1075 7.4761 3.8727 0.4308
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-15 GDSC1 -3.5618 3.1691 -3.9967 75.5389
SCC-9 GDSC1 -3.1254 0.5849 -3.1659 81.8882
CAL-27 GDSC1 -2.0675 3.0993 -2.3593 69.7489
BB30-HNC GDSC1 -1.7436 3.4119 -2.0731 67.2869
BHY GDSC1 -1.6459 2.1569 -1.7526 69.4488
SAT [Human HNSCC] GDSC1 -1.5277 2.9721 -1.7505 66.8698
Ca9-22 GDSC1 -1.4223 5.8184 -2.4112 61.6244
NCI-H3118 GDSC1 -1.3599 8.8538 -3.5129 58.4485
PE/CA-PJ15 GDSC1 -1.2104 3.8672 -1.5978 63.1421
PCI-15A GDSC1 -1.072 10.7036 -4.0127 56.1859
PCI-04B GDSC1 -0.8275 3.8711 -1.1814 60.4157
DOK GDSC1 -0.0513 4.2471 -0.4305 53.592
PCI-06A GDSC1 0.0773 4.169 -0.2695 52.4172
SKN-3 GDSC1 0.1889 8.8298 -1.8961 50.7796
OSC-19 GDSC1 0.4524 9.5375 -1.9422 49.2676
HO-1-N-1 GDSC1 0.8577 4.3745 0.5269 44.3341
SCC-4 GDSC1 0.9529 4.2357 0.6684 43.152
CAL-33 GDSC1 0.9874 6.8856 -0.2362 44.7572
OSC-20 GDSC1 1.1351 5.4409 0.4851 42.2178
HSC-3 GDSC1 1.2885 2.9071 1.2649 38.0558
JHU-011 GDSC1 1.2966 5.2585 0.7243 40.2913
SCC-25 GDSC1 1.3529 7.5226 -0.1283 42.1667
JHU-022 GDSC1 1.382 6.2348 0.4452 40.5603
KOSC-2 GDSC1 2.3748 5.2033 1.9048 27.3982
BICR 22 GDSC1 2.9413 4.1077 2.8679 17.7325
BICR 10 GDSC1 3.5325 4.4664 3.417 10.639
Detroit 562 GDSC1 4.2902 7.7737 2.5695 13.8061
HO-1-u-1 GDSC1 4.3075 5.4817 3.7299 4.7214
LB771-HNC GDSC1 4.3358 6.1539 3.4175 7.0819
PCI-30 GDSC1 4.4325 19.95 -3.4001 36.1847
BICR 31 GDSC1 4.6702 14.4902 -0.475 28.5657
HSC-2 GDSC1 6.3957 7.6335 3.9244 0.1752
HSC-4 GDSC1 6.4257 7.6709 3.9223 0.1709
SAS GDSC1 6.4332 8.7266 3.5316 1.6201
KON GDSC1 6.5032 7.8305 3.8951 0.2014
BICR 78 GDSC1 6.6972 8.8193 3.6121 0.99
PCI-38 GDSC1 6.755 8.3951 3.7903 0.3517
FaDu GDSC1 6.835 8.1502 3.9025 0.1115
BB49-HNC GDSC1 6.9032 8.8982 3.6665 0.6425
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 GDSC1 0.7144 4.9677 0.1914 46.2018
RT-4 GDSC1 1.6321 3.6577 1.5374 34.1935
CAL-29 GDSC1 1.8396 4.9339 1.4241 33.4704
SW1710 GDSC1 1.9629 3.3171 1.9367 29.6523
HT-1197 GDSC1 2.1736 3.0941 2.1687 26.8846
HT-1376 GDSC1 2.2078 4.344 2.0086 27.7068
RT-112 GDSC1 2.3037 3.5744 2.2695 25.4448
BFTC-905 GDSC1 2.4819 3.5611 2.4593 23.1432
TCCSUP GDSC1 2.531 3.8067 2.4802 22.711
UM-UC-3 GDSC1 2.556 4.24 2.4164 22.9833
639V GDSC1 2.7199 4.2312 2.5975 20.823
647V GDSC1 2.7934 4.8163 2.4968 21.0988
T24 GDSC1 3.4046 5.6422 2.7989 15.7948
J82 GDSC1 3.6433 6.4056 2.6718 15.653
SW780 GDSC1 3.9693 4.9234 3.6934 6.4018
KU-19-19 GDSC1 4.226 5.8082 3.4974 6.8587
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DSH1 GDSC1 -2.8347 2.2436 -3.0348 75.503
OMC-1 [Human cervical carcinoma] GDSC1 -2.5375 0.4616 -2.5553 79.7089
ME-180 GDSC1 -2.4203 3.6941 -2.8746 70.1022
Ca Ski GDSC1 -2.4173 0.0425 -2.4227 80.3439
HT-3 GDSC1 -2.31 0.8929 -2.3405 77.0744
OVMIU GDSC1 -1.42 3.777 -1.8044 64.646
BPH-1 GDSC1 -1.0258 1.9808 -1.0797 64.886
UWB1.289 GDSC1 -0.7244 4.5207 -1.2408 58.8787
C-33 A GDSC1 -0.3855 5.5273 -1.1887 55.5615
KGN GDSC1 0.0506 5.4098 -0.6762 52.2885
SW954 GDSC1 0.3322 3.5216 0.1574 49.8864
PEO1 GDSC1 0.5285 5.5028 -0.1915 48.1722
OVCA420 GDSC1 0.5838 5.7618 -0.2249 47.7414
PA-1 GDSC1 1.464 2.6853 1.4575 35.7643
DoTc2 4510 GDSC1 1.4723 9.0105 -0.678 42.504
CAL-39 GDSC1 1.4827 3.8053 1.3477 36.2613
NEC8 GDSC1 1.5267 2.6391 1.5226 34.9659
TC-YIK GDSC1 1.6078 3.2924 1.5646 34.1909
NCC-IT GDSC1 1.7918 2.6721 1.7904 31.6352
OV17R GDSC1 1.9541 3.7009 1.8771 30.0823
SiSo GDSC1 2.2792 4.8738 1.9208 27.8491
ACC-OV7 GDSC1 2.2877 4.503 2.0499 26.9677
LB831-BLC GDSC1 2.3088 4.0509 2.1926 25.912
OVCA433 GDSC1 2.4162 3.5081 2.3952 23.9538
NT2-D1 GDSC1 2.4431 4.2756 2.2839 24.521
JEG-3 GDSC1 2.4538 4.072 2.3456 24.0504
JHOS-3 GDSC1 2.6012 6.7235 1.4992 28.5831
HEY GDSC1 2.6784 3.8043 2.6386 20.7975
SW962 GDSC1 2.8215 5.3157 2.3363 22.0631
JAR GDSC1 2.967 4.1585 2.8845 17.4717
PWR-1E GDSC1 3.1118 4.7521 2.863 16.8095
SW756 GDSC1 3.4868 14.9977 -1.727 35.9598
C-4-I GDSC1 3.5833 9.4005 1.1435 25.8113
SiHa GDSC1 3.631 12.5849 -0.3986 31.9701
HEC-1 GDSC1 3.7467 5.0342 3.419 9.5214
SKN GDSC1 3.766 5.0002 3.4538 9.1683
SKG-IIIa GDSC1 3.804 4.2909 3.7649 6.7292
MS751 GDSC1 3.8397 4.3713 3.7813 6.4147
HeLa GDSC1 3.853 4.1642 3.843 5.9255
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032292)
2 AST1306, a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, exhibits antitumor activity both in vitro and in vivo. PLoS One. 2011;6(7):e21487.