Details of the Drug

General Information of Drug (ID: DMD8JIC)

Drug Name
P22077
Synonyms
1247819-59-5; P 22077; 1-[5-(2,4-Difluoro-phenylsulfanyl)-4-nitro-thiophen-2-yl]-ethanone; CHEMBL2159498; 1-[5-(2,4-difluorophenyl)sulfanyl-4-nitrothiophen-2-yl]ethanone; 1-[5-[(2,4-Difluorophenyl)thio]-4-nitro-2-thienyl]-ethanone; 1-(5-(2,4-difluorophenylthio)-4-nitrothiophen-2-yl)ethanone; P-22077; 1-(5-((2,4-Difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone; 1-{5-[(2,4-Difluorophenyl)sulfanyl]-4-nitrothiophen-2-yl}ethan-1-one; C12H7F2NO3S2; SCHEMBL2680945; DTXSID40677376; HMS3653G09; BCP07858; EX-A1445; 1-(5-((2,4-difluorophenyl)thio)-4-nitrothiophen-2-yl)ethan-1-one; 2624AH; BDBM50393440; MFCD22580421; s7133; ZINC91696068; AKOS024458186; CCG-267643; CS-1860; QC-8199; AC-32695; AK313221; AS-55923; DA-46729; HY-13865; AB0003913; FT-0707469; SW219709-1; EC-000.2542; J3.502.624J; Z1646327284; 1-[5-(2,4-difluorophenyl)sulfanyl-4-nitro-2-thienyl]ethanone; 1-[5-[(2,4-Difluorophenyl)thio]-4-nitro-2-thienyl]ethanon; 1-(5-((2,4-difluorophenyl)thio)-4-nitrothiophen-2-yl) ethanone
Indication
Disease Entry ICD 11 Status REF
Inflammation 1A00-CA43.1 Preclinical [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 315.3
Logarithm of the Partition Coefficient (xlogp) 4.1
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C12H7F2NO3S2
IUPAC Name
1-[5-(2,4-difluorophenyl)sulfanyl-4-nitrothiophen-2-yl]ethanone
Canonical SMILES
CC(=O)C1=CC(=C(S1)SC2=C(C=C(C=C2)F)F)[N+](=O)[O-]
InChI
InChI=1S/C12H7F2NO3S2/c1-6(16)11-5-9(15(17)18)12(20-11)19-10-3-2-7(13)4-8(10)14/h2-5H,1H3
InChIKey
RMAMGGNACJHXHO-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
46931953
CAS Number
1247819-59-5
TTD ID
D2K6DU

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Herpesvirus ubiquitin-specific protease (HAUSP) TTXU3EQ UBP7_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 6.3579 8.198 2.7303 0.221
ES1 GDSC2 2.8179 4.6474 2.2034 8.6978
U-CH2 GDSC2 2.9306 4.1982 2.5264 6.3031
EW-1 GDSC2 3.6072 6.1707 2.1277 6.7697
EW-12 GDSC2 3.6499 5.899 2.2954 5.6056
TC-71 GDSC2 3.7676 5.9052 2.3803 4.7846
ES5 GDSC2 3.7728 6.6306 2.0267 6.9755
SK-ES-1 GDSC2 3.95 5.7961 2.561 3.2688
NOS-1 [Human HNSCC] GDSC2 4.0954 6.8071 2.1743 5.2996
CAL-72 GDSC2 4.1551 6.6626 2.2846 4.5031
MHH-ES-1 GDSC2 4.396 6.1672 2.6633 1.894
EW-16 GDSC2 4.5258 8.2167 1.7906 6.6818
EW-11 GDSC2 4.5636 10.0739 0.9165 11.6903
CHSA8926 GDSC2 4.6361 7.2453 2.3171 3.4033
ES8 GDSC2 4.6656 7.3356 2.2936 3.4853
CADO-ES1 GDSC2 4.6689 6.236 2.7756 1.0082
CHSA0011 GDSC2 4.7709 7.418 2.3183 3.1746
HuO9 GDSC2 4.803 7.3423 2.3706 2.8409
ES6 GDSC2 4.9829 7.5353 2.3854 2.5009
ES4 GDSC2 5.0497 12.9213 -0.1251 15.9365
EW-22 GDSC2 5.0507 7.1628 2.5792 1.4779
EW-3 GDSC2 5.0823 8.1177 2.1836 3.4155
EW-24 GDSC2 5.1326 6.6787 2.8079 0.5191
G-292 clone A141B1 GDSC2 5.1811 7.8717 2.3459 2.4335
HuO-3N1 GDSC2 5.2576 8.2192 2.2362 2.8843
CHSA0108 GDSC2 5.3755 8.0384 2.3754 2.0505
A-673 GDSC2 5.4217 6.8119 2.872 0.2258
SaOS-2 GDSC2 5.488 11.8019 0.7229 10.701
CAL-78 GDSC2 5.5015 7.4273 2.6787 0.7028
SK-PN-DW GDSC2 5.5201 7.4863 2.6641 0.7386
EW-7 GDSC2 5.6027 7.4057 2.728 0.496
SJSA-1 GDSC2 5.6412 7.6364 2.6579 0.6824
MG-63 GDSC2 5.7242 7.6343 2.6924 0.5336
HOS GDSC2 5.7791 7.3148 2.8272 0.2055
EW-18 GDSC2 5.8227 7.7609 2.685 0.5051
EW-13 GDSC2 6.0606 8.0611 2.6686 0.4405
U2OS GDSC2 6.0688 8.1146 2.6525 0.4765
H-EMC-SS GDSC2 6.4913 9.14 2.4436 0.8425
ES7 GDSC2 6.7695 9.1072 2.5639 0.4099
NY GDSC2 6.8531 9.1722 2.5719 0.3668
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 162 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 2.7283 3.6883 2.5471 6.9602
SUP-B8 GDSC2 0.3908 3.149 0.1686 30.5323
MOLM-13 GDSC2 1.0475 2.6235 0.9896 23.1203
Mono-Mac-6 GDSC2 1.1626 2.8735 1.071 22.1419
TALL-1 [Human adult T-ALL] GDSC2 1.2528 4.6769 0.5899 24.3429
SU-DHL-5 GDSC2 1.5939 3.7331 1.3096 18.869
Farage GDSC2 1.7554 3.3848 1.5948 16.5695
P12-Ichikawa GDSC2 1.8168 3.2717 1.6928 15.7551
WSU-DLCL2 GDSC2 1.8507 3.0915 1.7729 15.1677
MV4-11 GDSC2 1.9567 3.1023 1.8857 14.0688
A3/Kawakami GDSC2 2.0628 2.9273 2.0319 12.7934
NB4 GDSC2 2.063 3.257 1.9652 13.1462
CRO-AP2 GDSC2 2.1497 3.4906 1.9929 12.6002
DEL GDSC2 2.1677 2.9 2.1475 11.6858
Kasumi-1 GDSC2 2.1723 3.3442 2.0612 12.1233
HL-60 GDSC2 2.2321 3.1956 2.1645 11.2892
U-698-M GDSC2 2.2579 3.6812 2.046 11.8275
JeKo-1 GDSC2 2.2733 3.0821 2.233 10.7307
KY821 GDSC2 2.3117 3.3507 2.2115 10.6672
SKM-1 GDSC2 2.3144 3.4229 2.1933 10.7547
KMOE-2 GDSC2 2.3573 4.53 1.8017 12.8534
P32/ISH GDSC2 2.3702 3.258 2.3 9.9182
JSC-1 GDSC2 2.382 3.5852 2.2138 10.3408
QIMR-WIL GDSC2 2.3908 10.7291 -1.1836 27.9856
SIG-M5 GDSC2 2.4219 3.3018 2.3451 9.4353
THP-1 GDSC2 2.5028 3.4403 2.3931 8.8055
MHH-CALL-2 GDSC2 2.5331 3.6146 2.3665 8.8225
NU-DUL-1 GDSC2 2.5407 3.4642 2.4267 8.4506
MHH-CALL-4 GDSC2 2.5456 4.6128 1.9535 11.2205
RCH-ACV GDSC2 2.5649 4.0188 2.2388 9.4328
DoHH2 GDSC2 2.5667 3.3985 2.4756 8.0631
NK-92MI GDSC2 2.5783 3.5758 2.4292 8.2714
697 GDSC2 2.5854 3.2788 2.5295 7.6836
MOLM-16 GDSC2 2.6034 3.4798 2.4896 7.8225
BV-173 GDSC2 2.6068 3.5798 2.4585 7.9826
Jurkat GDSC2 2.6145 3.5697 2.4705 7.8811
KE-37 GDSC2 2.6275 3.4133 2.5373 7.4497
OCI-Ly7 GDSC2 2.642 3.4496 2.5415 7.3621
PF-382 GDSC2 2.6456 5.3305 1.7103 12.3506
KOPN-8 GDSC2 2.6703 3.5317 2.5441 7.2231
OCI-AML-3 GDSC2 2.6709 3.9584 2.3745 8.2065
OCI-M1 GDSC2 2.7125 3.3587 2.6465 6.4656
JVM-2 GDSC2 2.7324 4.3536 2.2589 8.6664
BC-3 GDSC2 2.7505 3.6781 2.5747 6.7074
MC116 GDSC2 2.758 3.3367 2.7024 5.953
SU-DHL-16 GDSC2 2.8094 5.3671 1.8461 10.9459
BONNA-12 GDSC2 2.8157 4.2504 2.3894 7.5619
H9 GDSC2 2.8515 4.1108 2.4896 6.8187
HEL GDSC2 2.883 5.623 1.7878 11.0635
BC-1 GDSC2 2.8906 8.6347 0.2981 19.7622
DG-75 GDSC2 2.9166 4.5831 2.3283 7.5776
RL GDSC2 2.9244 3.7105 2.7435 5.0105
GA-10 GDSC2 2.9271 3.8315 2.6929 5.3019
MOLP-8 GDSC2 2.9416 3.8555 2.6968 5.2232
KMS-11 GDSC2 2.9418 5.2559 2.0224 9.4031
ALL-SIL GDSC2 2.9455 4.1806 2.5492 6.1092
ARH-77 GDSC2 3.0152 4.0653 2.6715 5.1058
MOLT-16 GDSC2 3.0173 4.0232 2.6936 4.9626
ALL-PO GDSC2 3.0248 4.4205 2.5089 6.0824
WSU-NHL GDSC2 3.0518 4.9534 2.2715 7.4801
RPMI-8402 GDSC2 3.0616 4.4188 2.5438 5.7395
BE-13 GDSC2 3.0785 4.8584 2.3425 6.9472
SCC-3 GDSC2 3.0795 3.9197 2.803 4.0656
ATN-1 GDSC2 3.1054 4.1173 2.732 4.4161
IM-9 GDSC2 3.1202 4.1483 2.7305 4.3756
SU-DHL-1 GDSC2 3.134 4.3398 2.649 4.8405
CTB-1 GDSC2 3.1521 4.5783 2.5472 5.4226
LC4-1 GDSC2 3.1784 4.5928 2.5632 5.2382
CML-T1 GDSC2 3.2047 4.3278 2.7183 4.1772
BALL-1 GDSC2 3.2332 4.4721 2.6713 4.3849
HC-1 GDSC2 3.2792 4.8366 2.5287 5.1479
JJN-3 GDSC2 3.2833 4.7269 2.587 4.767
P30/OHK GDSC2 3.3264 4.6375 2.6678 4.1284
OCI-AML-2 GDSC2 3.328 4.466 2.7549 3.5725
MOLT-13 GDSC2 3.3555 4.7509 2.6352 4.2513
Karpas-231 GDSC2 3.3683 4.7285 2.6569 4.0778
Jiyoye GDSC2 3.4337 4.9148 2.6166 4.1509
EoL-1 GDSC2 3.4358 4.9223 2.6145 4.1585
TUR GDSC2 3.4606 4.8999 2.6454 3.8969
OCI-Ly19 GDSC2 3.5033 5.2759 2.4917 4.7525
EM-2 GDSC2 3.5103 5.2492 2.5105 4.6154
RS4;11 GDSC2 3.5173 5.2927 2.4943 4.699
CESS GDSC2 3.5231 5.3523 2.4692 4.8417
KMS-12-BM GDSC2 3.5439 5.0862 2.6173 3.8563
RPMI-6666 GDSC2 3.5835 5.4011 2.4915 4.5444
SU-DHL-10 GDSC2 3.5914 5.292 2.5514 4.1489
MM1.S GDSC2 3.5923 5.9855 2.2082 6.3025
MHH-PREB-1 GDSC2 3.5931 4.9775 2.7078 3.1673
GR-ST GDSC2 3.6086 5.8889 2.2688 5.8794
A4/Fukuda GDSC2 3.614 5.3774 2.5263 4.2492
Karpas-620 GDSC2 3.652 5.5929 2.4484 4.6421
VAL GDSC2 3.6598 5.6354 2.4333 4.7172
SR GDSC2 3.6784 7.7049 1.42 10.9791
Karpas-45 GDSC2 3.7122 5.2205 2.6749 3.0916
CA46 GDSC2 3.7288 5.628 2.4879 4.2086
HAL-01 GDSC2 3.7344 5.4642 2.572 3.6746
TK [Human B-cell lymphoma] GDSC2 3.7552 5.4753 2.5815 3.5687
RPMI-8226 GDSC2 3.7563 5.4478 2.5956 3.4789
GDM-1 GDSC2 3.7598 5.6158 2.5163 3.9599
NCI-H929 GDSC2 3.7635 5.3699 2.6385 3.1995
ME1 GDSC2 3.79 5.3331 2.6746 2.9208
Raji GDSC2 3.7963 5.5067 2.5952 3.3914
L-428 GDSC2 3.8016 5.3727 2.6635 2.9632
KG-1 GDSC2 3.8286 7.3054 1.7351 8.6456
NALM-6 GDSC2 3.85 5.4467 2.6609 2.8763
Karpas-1106P GDSC2 3.9046 6.9055 1.9895 6.8797
SUP-T1 GDSC2 3.9337 5.8096 2.5436 3.4075
RC-K8 GDSC2 3.9545 6.4067 2.2697 5.0316
JVM-3 GDSC2 3.9645 5.8524 2.5438 3.3418
HT GDSC2 4.0285 8.2596 1.4144 10.0967
KM-H2 GDSC2 4.0394 5.9237 2.5593 3.0973
DB GDSC2 4.0627 5.8456 2.6111 2.7475
CTV-1 GDSC2 4.1233 5.9837 2.5849 2.7865
KCL-22 GDSC2 4.1427 6.0214 2.5795 2.7818
CCRF-CEM GDSC2 4.2004 5.9642 2.6413 2.3258
ST486 GDSC2 4.2108 6.008 2.6275 2.3859
SUP-B15 GDSC2 4.2668 6.403 2.4796 3.1306
EJM GDSC2 4.3005 6.2035 2.5919 2.4333
MLMA GDSC2 4.3363 8.4271 1.5574 8.4942
MY-M12 GDSC2 4.3765 7.7348 1.9205 6.2239
ROS-50 GDSC2 4.3915 6.7546 2.3939 3.3967
AMO1 GDSC2 4.4608 5.8629 2.8282 0.9936
SUP-HD1 GDSC2 4.5111 7.7153 2.0197 5.3541
LP-1 GDSC2 4.5129 6.5062 2.5786 2.1694
Loucy GDSC2 4.5278 6.3229 2.6673 1.6873
PL-21 GDSC2 4.629 6.8838 2.4762 2.5405
SK-MM-2 GDSC2 4.6588 7.1045 2.3944 2.9378
Namalwa GDSC2 4.7702 6.2644 2.8113 0.7666
ML-2 GDSC2 4.7932 7.0372 2.4997 2.1781
WIL2 NS GDSC2 4.8078 6.1928 2.8559 0.5721
Karpas-422 GDSC2 4.8825 10.9501 0.7172 12.0465
EB2 GDSC2 4.893 7.1211 2.5167 1.9597
OPM-2 GDSC2 4.9416 6.7877 2.6806 1.1451
P31/FUJ GDSC2 4.9428 6.2516 2.8897 0.381
BL-41 GDSC2 4.9524 6.4255 2.8284 0.5666
Ramos.2G6.4C10 GDSC2 4.9667 6.4155 2.8382 0.5247
U266B1 GDSC2 5.0499 8.1975 2.1292 3.7602
SU-DHL-4 GDSC2 5.0551 6.3058 2.914 0.2656
Reh GDSC2 5.1161 6.6703 2.8042 0.5407
SU-DHL-8 GDSC2 5.1614 6.6327 2.8366 0.4176
MN-60 GDSC2 5.2132 7.1781 2.6497 1.022
NOMO-1 GDSC2 5.2301 6.6278 2.8653 0.3103
Karpas-299 GDSC2 5.2676 6.7782 2.8254 0.3956
L-363 GDSC2 5.3033 6.6677 2.8788 0.2513
YT GDSC2 5.3234 6.7146 2.8698 0.2637
MOLT-4 GDSC2 5.364 7.0546 2.762 0.525
DND-41 GDSC2 5.4438 7.2631 2.7167 0.6172
SUP-M2 GDSC2 5.4777 6.6984 2.9311 0.114
L-1236 GDSC2 5.5918 8.5036 2.289 2.2037
Hs 445 GDSC2 5.6011 7.1555 2.8176 0.2776
L-540 GDSC2 5.6467 7.1674 2.8303 0.2374
HH [Human lymphoma] GDSC2 5.7013 8.0342 2.531 1.0768
Granta-519 GDSC2 5.7495 7.4931 2.7535 0.3651
Ku812 GDSC2 5.7606 7.361 2.8043 0.2526
Daudi GDSC2 5.7725 7.2594 2.8438 0.1793
K-562 GDSC2 5.8141 7.2712 2.8546 0.1534
MEG-01 GDSC2 5.8406 8.1006 2.5655 0.8553
HDLM-2 GDSC2 6.0056 7.7376 2.7626 0.2585
SU-DHL-6 GDSC2 6.0186 7.7658 2.7575 0.2642
LAMA-84 GDSC2 6.1285 7.7943 2.7871 0.1855
NKM-1 GDSC2 6.3126 8.3097 2.6752 0.3335
VL51 GDSC2 6.6778 8.5932 2.7085 0.1843
⏷ Show the Full List of 162 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCE-4 GDSC2 4.5577 12.6586 -0.3608 18.2299
KYSE-50 GDSC2 4.5898 6.9923 2.4048 2.9926
ESO-26 GDSC2 4.7209 6.66 2.6241 1.651
KYAE-1 GDSC2 4.927 6.9663 2.5997 1.521
OACM5.1 C GDSC2 5.089 7.3493 2.5205 1.7039
KYSE-220 GDSC2 5.0969 6.9585 2.6841 0.9869
ESO-51 GDSC2 5.5901 7.7184 2.605 0.8925
OACP4 C GDSC2 5.8739 8.241 2.5259 0.9671
SK-GT-4 GDSC2 5.9764 7.9648 2.6709 0.4708
FLO-1 GDSC2 6.519 8.6262 2.6402 0.3372
TE-12 GDSC2 7.1063 9.6588 2.4946 0.4401
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 4.6964 8.0886 1.9635 5.3193
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LA-N-6 GDSC2 2.3595 3.6476 2.1676 10.6991
KP-N-YS GDSC2 2.693 4.6573 2.0779 9.9181
NB(TU)1 GDSC2 2.8803 4.1478 2.501 6.6422
CHP-134 GDSC2 2.9397 3.9729 2.6411 5.5681
IMR-5 GDSC2 2.9776 4.1281 2.6053 5.6486
SK-N-DZ GDSC2 3.1199 4.1166 2.7458 4.2805
MHH-NB-11 GDSC2 3.1293 4.6307 2.5009 5.787
SK-N-BE(2)-M17 GDSC2 3.2881 5.6105 2.1494 7.522
SJNB-14 GDSC2 3.3189 5.1105 2.4251 5.6871
SiMa GDSC2 3.3798 5.3986 2.3314 6.1053
SK-N-MC-IXC GDSC2 3.4027 4.7771 2.6605 3.9592
SK-N-SH GDSC2 3.5566 5.5482 2.3978 5.2033
SJNB-6 GDSC2 3.6285 6.9076 1.7778 8.9059
SJNB-10 GDSC2 3.7654 6.0393 2.3128 5.2095
NB1 GDSC2 3.7778 5.5439 2.5641 3.6238
SJNB-13 GDSC2 3.8605 5.7943 2.5007 3.8266
CHP-126 GDSC2 3.8811 5.749 2.5369 3.5607
SJNB-12 GDSC2 4.0295 6.4475 2.3023 4.6651
SK-N-AS GDSC2 4.3571 7.3667 2.0836 5.2877
NH-12 GDSC2 4.39 8.4915 1.5641 8.3308
SJNB-17 GDSC2 4.4809 6.8552 2.4023 3.1908
CHP-212 GDSC2 4.7726 7.1441 2.4415 2.5097
KP-N-YN GDSC2 4.9194 7.8322 2.2179 3.485
Kelly GDSC2 5.0531 6.622 2.7961 0.6078
GOTO GDSC2 5.0613 7.0274 2.6398 1.2014
SJNB-5 GDSC2 5.1991 7.0856 2.6799 0.9173
TGW GDSC2 5.2339 6.9158 2.7605 0.6073
SK-N-FI GDSC2 5.3115 7.1157 2.7171 0.7001
GI-ME-N GDSC2 5.336 9.0235 1.9232 4.4204
KP-N-RT-BM-1 GDSC2 5.4293 7.3151 2.691 0.7092
NB69 GDSC2 5.5577 8.0784 2.4478 1.5329
SJNB-7 GDSC2 5.8848 7.1886 2.9067 0.0788
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 4.2098 6.2874 2.4977 3.1314
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HDQ-P1 GDSC2 2.1544 3.3219 2.0478 12.2781
MDA-MB-330 GDSC2 2.4864 3.8028 2.2451 9.7161
COLO 824 GDSC2 2.4918 3.482 2.3677 8.9959
HCC1806 GDSC2 2.5757 3.6964 2.3815 8.555
Evsa-T GDSC2 2.7807 3.6518 2.6171 6.3359
MDA-MB-453 GDSC2 2.8746 3.9521 2.5855 6.1501
HCC2157 GDSC2 2.9435 3.9014 2.6778 5.3306
T-47D GDSC2 3.051 4.8844 2.3048 7.2734
HCC1599 GDSC2 3.1357 4.55 2.5466 5.4789
CAL-51 GDSC2 3.1423 4.9626 2.3475 6.7123
CAL-120 GDSC2 3.2424 4.376 2.7272 4.0032
MDA-MB-361 GDSC2 3.2562 6.2333 1.8111 9.7492
DU4475 GDSC2 3.3198 4.5316 2.7153 3.8467
HCC1937 GDSC2 3.3285 6.0874 1.9446 8.6967
MDA-MB-468 GDSC2 3.5284 5.0726 2.6121 3.9284
MDA-MB-175-VII GDSC2 3.5717 5.3741 2.4959 4.5474
BT-474 GDSC2 3.6985 7.8428 1.3672 11.2457
UACC-812 GDSC2 3.9291 6.266 2.3201 4.7799
CAL-148 GDSC2 3.975 6.5721 2.2037 5.3904
HCC1569 GDSC2 3.9993 8.0162 1.5126 9.5762
MRK-nu-1 GDSC2 4.0078 5.5882 2.6966 2.353
EFM-19 GDSC2 4.0424 6.2025 2.4288 3.871
HCC1187 GDSC2 4.0434 6.1591 2.4502 3.7403
HCC1419 GDSC2 4.0475 17.0788 -2.9616 28.6412
YMB-1-E GDSC2 4.0924 7.6118 1.7803 7.7163
JIMT-1 GDSC2 4.158 7.3715 1.9445 6.5606
HCC1500 GDSC2 4.3019 8.5362 1.4796 9.0398
BT-20 GDSC2 4.3539 8.1374 1.7106 7.535
EFM-192A GDSC2 4.4049 6.7486 2.4049 3.3094
AU565 GDSC2 4.4744 7.3439 2.1712 4.535
BT-549 GDSC2 4.547 7.7087 2.0462 5.1265
HCC1143 GDSC2 4.5673 7.1376 2.325 3.4773
HCC1428 GDSC2 4.6552 12.9914 -0.4517 18.3953
MDA-MB-415 GDSC2 4.6658 7.7377 2.1083 4.5388
HCC2218 GDSC2 4.9721 7.0938 2.5689 1.6125
BT-483 GDSC2 5.2459 7.8495 2.3892 2.1394
MCF-7 GDSC2 5.2679 7.248 2.6467 0.9878
Hs 578T GDSC2 5.3042 7.4321 2.59 1.1804
HCC38 GDSC2 5.3552 7.4607 2.602 1.0881
OCUB-M GDSC2 5.3776 7.0715 2.7612 0.5198
CAMA-1 GDSC2 5.4592 7.3765 2.6802 0.7254
HCC70 GDSC2 5.5678 7.3989 2.7166 0.5466
MFM-223 GDSC2 5.632 7.035 2.8708 0.1698
CAL-85-1 GDSC2 5.6635 8.2864 2.4134 1.576
HCC1954 GDSC2 5.6749 7.5274 2.7121 0.5038
UACC-893 GDSC2 5.6944 8.1172 2.4953 1.2172
MDA-MB-157 GDSC2 5.8283 7.7785 2.6807 0.5138
ZR-75-30 GDSC2 5.8589 7.6315 2.7455 0.3415
MDA-MB-436 GDSC2 5.8715 7.6839 2.7316 0.368
HCC1395 GDSC2 6.18 7.8822 2.7753 0.1919
MDA-MB-231 GDSC2 6.2412 8.0976 2.7231 0.2636
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-423MG GDSC2 3.065 4.4791 2.5174 5.8936
Daoy GDSC2 3.2407 4.3584 2.7345 3.9622
U-118MG GDSC2 3.4002 5.3123 2.3912 5.6692
8-MG-BA GDSC2 3.4386 4.7267 2.7142 3.5216
D-542MG GDSC2 3.5553 5.2933 2.5233 4.4173
AM-38 GDSC2 3.6496 6.8656 1.8152 8.6159
A-172 GDSC2 3.657 6.7083 1.8992 8.071
MOG-G-UVW GDSC2 3.726 5.8329 2.3852 4.8544
PFSK-1 GDSC2 3.7541 5.6287 2.5059 4.0377
D283 Med GDSC2 3.8374 5.5414 2.6069 3.23
D-566MG GDSC2 3.9174 6.4102 2.2415 5.2906
D-502MG GDSC2 3.9278 7.1164 1.9029 7.3595
GB-1 GDSC2 3.9598 5.8059 2.5629 3.2368
DK-MG GDSC2 3.9639 6.27 2.3426 4.5639
LN-18 GDSC2 4.0022 6.5325 2.2422 5.0929
SK-MG-1 GDSC2 4.1201 6.048 2.5528 2.9795
42-MG-BA GDSC2 4.3689 6.554 2.4727 2.9871
SF268 GDSC2 4.6052 9.7991 1.0805 10.6641
U-87MG ATCC GDSC2 4.687 9.0925 1.4798 8.1705
MOG-G-CCM GDSC2 4.7495 7.1288 2.4354 2.5764
U-251MG GDSC2 4.8536 6.7466 2.6549 1.3501
SF295 GDSC2 4.857 6.499 2.7575 0.9046
DBTRG-05MG GDSC2 4.8923 7.5883 2.3117 3.0199
CAS-1 GDSC2 4.9984 6.4406 2.8419 0.4933
LN-405 GDSC2 5.0008 6.6509 2.7623 0.7657
LN-229 GDSC2 5.0736 7.8286 2.3067 2.7795
NMC-G1 GDSC2 5.0809 6.3515 2.9074 0.2707
D-336MG GDSC2 5.1258 8.8019 1.8994 4.9016
YKG-1 GDSC2 5.1549 6.6674 2.8212 0.4659
D-263MG GDSC2 5.1995 6.7857 2.7952 0.5185
Hs 683 GDSC2 5.2007 6.6678 2.8394 0.3903
M059J GDSC2 5.2222 7.0024 2.7224 0.744
D-245MG GDSC2 5.2321 7.8615 2.3769 2.2156
GaMG GDSC2 5.4138 10.5411 1.2712 7.88
GI-1 GDSC2 5.5161 7.8155 2.5342 1.2168
YH-13 GDSC2 5.522 7.739 2.5671 1.0839
Onda 10 GDSC2 5.5426 7.6145 2.6246 0.8579
KINGS-1 GDSC2 5.566 7.3732 2.7254 0.5223
H4 GDSC2 5.5781 7.7596 2.5839 0.9772
SF126 GDSC2 5.5889 7.2617 2.7751 0.3793
Onda 11 GDSC2 5.623 8.1422 2.4527 1.4505
ONS-76 GDSC2 5.6646 7.0817 2.8664 0.169
T98G GDSC2 5.6732 7.3672 2.7695 0.3581
SW1783 GDSC2 5.6929 8.0153 2.5347 1.0697
KNS-42 GDSC2 5.7448 7.2779 2.8275 0.214
KNS-81-FD GDSC2 5.779 7.535 2.7497 0.3624
KALS-1 GDSC2 5.8063 8.6918 2.3162 1.8501
Becker GDSC2 5.8698 7.3634 2.8428 0.1588
SF539 GDSC2 5.924 7.3796 2.8563 0.1296
SW1088 GDSC2 6.1294 7.8276 2.776 0.2025
D-247MG GDSC2 6.1456 8.3675 2.5905 0.6035
SNB-75 GDSC2 6.2403 8.1969 2.688 0.331
D-392MG GDSC2 6.5272 8.5915 2.6553 0.306
KS-1 [Human Krukenberg tumour] GDSC2 6.7132 8.8699 2.6262 0.3063
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC2 3.056 4.9743 2.2648 7.5084
TGBC24TKB GDSC2 5.1274 7.7782 2.3577 2.4453
TGBC1TKB GDSC2 5.5565 7.1804 2.7919 0.3521
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KLE GDSC2 2.6199 4.8936 1.895 11.3051
ESS-1 GDSC2 3.5905 4.9955 2.697 3.2409
RL95-2 GDSC2 3.8448 12.2087 -0.6936 21.589
MFE-319 GDSC2 3.8675 6.0926 2.3608 4.6705
MFE-296 GDSC2 4.3481 7.429 2.0478 5.5203
AN3-CA GDSC2 4.6434 6.9025 2.4761 2.5189
EN GDSC2 4.9206 6.91 2.62 1.4348
MFE-280 GDSC2 6.5962 8.6897 2.6463 0.3029
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-1M GDSC2 2.5727 4.0892 2.2165 9.5339
LB2241-RCC GDSC2 2.9127 4.8108 2.214 8.3027
KTCTL-195 GDSC2 2.9486 4.3584 2.4671 6.6055
KTCTL-140 GDSC2 3.1434 4.6093 2.5241 5.5958
OS-RC-2 GDSC2 3.3285 4.7382 2.6192 4.4303
786-O GDSC2 3.3616 6.5406 1.7455 9.8517
KTCTL-13 GDSC2 3.4948 6.5836 1.8328 8.9272
BB65-RCC GDSC2 3.583 6.0596 2.1641 6.6045
A-498 GDSC2 3.5909 9.0603 0.6737 15.5954
BFTC-909 GDSC2 3.6383 6.9372 1.7707 8.9237
A-704 GDSC2 3.7147 14.3661 -1.8764 26.3604
Caki-1 GDSC2 3.7651 5.6008 2.5273 3.8795
SW156 GDSC2 3.8455 6.2023 2.2914 5.1508
UO-31 GDSC2 3.8871 5.888 2.4739 3.9318
SW13 GDSC2 4.2702 6.2678 2.5442 2.754
KTCTL-21 GDSC2 4.3013 7.1672 2.1415 5.0575
KMRC-20 GDSC2 4.4054 6.3734 2.5766 2.3465
KTCTL-26A GDSC2 4.6716 6.8673 2.5076 2.3101
HA7-RCC GDSC2 4.8374 7.1979 2.4536 2.3533
RXF 393L GDSC2 4.9735 7.8113 2.2584 3.1813
CAL-54 GDSC2 5.0572 9.0002 1.7657 5.777
769-P GDSC2 5.1809 6.8582 2.7601 0.6432
LB996-RCC GDSC2 5.1966 10.0009 1.3857 7.6626
ACHN GDSC2 5.2343 7.7633 2.4197 2.0074
NCC021 GDSC2 5.2344 7.3634 2.5852 1.2649
KMRC-1 GDSC2 5.434 6.7544 2.8965 0.1769
NCC010 GDSC2 5.4718 7.9596 2.4554 1.5854
RCC10RGB GDSC2 5.5975 7.2369 2.7873 0.3464
LB1047-RCC GDSC2 5.7112 8.0894 2.5138 1.1332
VMRC-RCZ GDSC2 5.758 7.5168 2.7482 0.3742
VMRC-RCW GDSC2 6.0344 7.7203 2.779 0.2212
SN12C GDSC2 6.1268 7.869 2.7609 0.2282
TK-10 GDSC2 6.4542 8.808 2.551 0.5625
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LS411N GDSC2 1.8065 6.7892 0.2063 24.0828
COLO 320HSR GDSC2 2.8344 4.1478 2.4555 7.0895
HT115 GDSC2 3.0549 4.3278 2.5822 5.5222
SW1463 GDSC2 3.3455 4.8048 2.6 4.5027
MDST8 GDSC2 3.4195 5.2412 2.4423 5.2918
C2BBe1 GDSC2 3.4375 5.4096 2.3727 5.6822
NCI-H716 GDSC2 3.4749 5.4618 2.3766 5.5547
SNU-C5 GDSC2 3.5248 9.033 0.6336 16.0084
SW48 GDSC2 3.6637 8.0222 1.2502 12.0466
LS123 GDSC2 3.7347 5.7115 2.4512 4.4226
CW-2 GDSC2 3.7513 6.1195 2.2628 5.5554
HCT 15 GDSC2 3.7771 6.3657 2.1607 6.1285
COLO205 GDSC2 3.7986 5.5395 2.5808 3.4743
GP5d GDSC2 3.9054 6.7753 2.054 6.4782
HT-29 GDSC2 4.063 5.695 2.6814 2.3395
SW626 GDSC2 4.1034 7.0821 2.0466 6.061
KM12 GDSC2 4.1914 11.1343 0.1146 16.9038
DiFi GDSC2 4.2728 7.965 1.7372 7.5582
RKO GDSC2 4.2996 6.1312 2.6242 2.2553
SW620 GDSC2 4.4298 6.3945 2.5812 2.2825
SNU-175 GDSC2 4.5204 6.3312 2.6597 1.7361
CL-11 GDSC2 4.6079 7.3366 2.2582 3.7852
HCT 116 GDSC2 4.6247 6.6655 2.5704 2.0498
HT-55 GDSC2 4.6774 6.4368 2.6964 1.3571
HCC2998 GDSC2 4.7752 8.6301 1.7593 6.3539
COLO 678 GDSC2 4.9564 8.1045 2.1164 3.9826
SNU-407 GDSC2 5.1252 7.3604 2.5339 1.6015
NCI-H747 GDSC2 5.159 7.2091 2.6122 1.2236
T84 GDSC2 5.1625 7.9246 2.313 2.6235
LS1034 GDSC2 5.1804 6.6528 2.8368 0.4074
RCM-1 [Human ESC] GDSC2 5.1978 11.3259 0.7548 11.1434
SW948 GDSC2 5.2462 6.8525 2.7894 0.5096
SNU-C1 GDSC2 5.3085 7.5567 2.5418 1.3766
SNU-283 GDSC2 5.3395 7.2482 2.6782 0.8152
SNU-61 GDSC2 5.3803 7.5644 2.5721 1.1846
SK-CO-1 GDSC2 5.3907 7.1744 2.7281 0.6134
SNU-81 GDSC2 5.4127 7.3414 2.6739 0.7781
SW1417 GDSC2 5.4386 7.1844 2.744 0.537
SW1116 GDSC2 5.4928 7.1398 2.7819 0.4044
LS180 GDSC2 5.5729 7.1728 2.8009 0.3247
SW837 GDSC2 5.6947 7.58 2.7006 0.5257
CaR-1 GDSC2 5.7747 7.4976 2.7614 0.3374
CCK-81 GDSC2 5.9164 7.7281 2.7328 0.3484
SNU-C2B GDSC2 5.9182 8.7551 2.3433 1.6271
NCI-H508 GDSC2 5.986 7.3727 2.8798 0.0923
LoVo GDSC2 6.1387 8.4148 2.5703 0.6636
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 4.5871 6.769 2.5036 2.4577
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC2 2.467 3.097 2.4393 8.7215
Huh-7 GDSC2 3.3975 7.0233 1.5338 11.0658
JHH-2 GDSC2 3.5556 6.0313 2.1567 6.724
Hep-G2/C3A GDSC2 3.7484 11.698 -0.5162 21.0912
JHH-6 GDSC2 3.9338 16.0874 -2.5583 27.8402
SK-HEP-1 GDSC2 4.1636 7.405 1.9322 6.6226
JHH-1 GDSC2 4.2888 6.7088 2.3505 3.8415
JHH-7 GDSC2 4.3573 6.1102 2.6669 1.933
HuH-1 GDSC2 4.8882 6.6953 2.6928 1.1457
SNU-398 GDSC2 4.9815 6.8875 2.6588 1.1988
HLE GDSC2 5.2048 7.4959 2.5168 1.592
JHH-4 GDSC2 5.3247 12.2723 0.386 12.7976
SNU-423 GDSC2 5.3525 8.5558 2.1408 3.2415
SNU-387 GDSC2 5.8561 7.5226 2.7829 0.2647
SNU-449 GDSC2 6.4044 8.1582 2.7603 0.1667
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 182 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SBC-1 GDSC2 1.7389 3.5414 1.5297 17.0022
HCC33 GDSC2 1.8151 3.8109 1.522 16.709
COR-L32 GDSC2 1.9652 4.2873 1.4994 16.2046
NCI-H835 GDSC2 2.0001 3.979 1.6587 15.1386
Lu-134-A GDSC2 2.2137 4.223 1.7866 13.5112
NCI-H1770 GDSC2 2.4551 4.574 1.8807 12.0029
NCI-H446 GDSC2 2.4794 10.0676 -0.7764 26.1214
COR-L303 GDSC2 2.5604 3.4146 2.4638 8.1567
ABC-1 GDSC2 2.5613 3.756 2.3431 8.8368
NCI-H2081 GDSC2 2.5657 3.5764 2.4154 8.4041
NCI-H322M GDSC2 2.573 3.4553 2.4646 8.0961
IST-SL1 GDSC2 2.5784 3.596 2.4221 8.3115
NCI-H847 GDSC2 2.6699 3.694 2.4828 7.5755
COR-L311 GDSC2 2.6812 3.8824 2.4176 7.9103
NCI-H2171 GDSC2 2.7604 3.5422 2.6375 6.3048
LB647-SCLC GDSC2 2.8005 4.0461 2.4682 7.1409
NCI-H2291 GDSC2 2.8431 4.3256 2.381 7.5128
NCI-H292 GDSC2 2.8528 9.1648 0.0009 21.3936
EPLC-272H GDSC2 2.8951 4.2051 2.4886 6.6643
UMC-11 GDSC2 2.903 9.1864 0.0337 21.0691
NCI-H1876 GDSC2 3.1397 4.2514 2.6978 4.5155
COR-L321 GDSC2 3.1564 4.2274 2.7248 4.2909
NCI-H1694 GDSC2 3.2117 6.2676 1.7562 10.2265
NCI-H2196 GDSC2 3.2187 4.7747 2.5078 5.4626
NCI-H209 GDSC2 3.2377 4.6302 2.5963 4.845
NCI-H1963 GDSC2 3.2676 5.603 2.1358 7.6684
NCI-H720 GDSC2 3.2805 4.8596 2.5183 5.2096
BEN GDSC2 3.3242 5.1772 2.3961 5.855
HCC827 GDSC2 3.3337 6.0061 1.9896 8.3982
NCI-H838 GDSC2 3.3341 4.6063 2.6899 3.9666
EBC-1 GDSC2 3.3358 6.8983 1.5452 11.1743
NCI-H748 GDSC2 3.3517 5.2102 2.4025 5.735
SBC-3 GDSC2 3.4203 4.8993 2.6137 4.2065
Lu-135 GDSC2 3.4404 5.1693 2.495 4.9015
SBC-5 GDSC2 3.4665 5.2147 2.4932 4.8419
NCI-H740 GDSC2 3.5217 6.5543 1.869 8.6257
NCI-H64 GDSC2 3.5296 6.2074 2.0484 7.477
CPC-N GDSC2 3.5805 6.1868 2.0989 7.0215
NCI-H1581 GDSC2 3.5817 5.0635 2.657 3.5123
NCI-H2369 GDSC2 3.6029 5.4492 2.4825 4.5519
NCI-H1975 GDSC2 3.6392 6.5921 1.9431 7.8437
NCI-H250 GDSC2 3.6431 7.112 1.6874 9.4284
NCI-H650 GDSC2 3.6462 5.3553 2.5612 3.9522
NCI-H1688 GDSC2 3.6469 5.245 2.6159 3.6092
NCI-H146 GDSC2 3.654 5.8757 2.3102 5.5027
NCI-H460 GDSC2 3.6809 5.0671 2.7274 2.8398
NCI-H2342 GDSC2 3.6835 5.5538 2.4911 4.2979
NCI-H1092 GDSC2 3.7211 5.591 2.5004 4.1493
NCI-H524 GDSC2 3.7751 5.6899 2.4911 4.08
NCI-H1155 GDSC2 3.7868 5.4783 2.6023 3.3693
COR-L23 GDSC2 3.7977 5.782 2.4623 4.2052
Calu-6 GDSC2 3.815 6.0124 2.3622 4.7841
NCI-H2029 GDSC2 3.8614 5.331 2.7236 2.4769
COR-L88 GDSC2 3.8686 6.1441 2.3364 4.8182
NCI-H345 GDSC2 3.8788 5.4049 2.7 2.5827
NCI-H1836 GDSC2 3.9414 6.0009 2.457 3.9158
NCI-H1869 GDSC2 3.9555 5.8374 2.545 3.3536
NCI-H2373 GDSC2 3.9636 6.7261 2.1205 5.9291
HCC366 GDSC2 3.965 7.0053 1.9848 6.7633
NCI-H513 GDSC2 3.9707 8.543 1.2304 11.3451
NCI-H2795 GDSC2 4.0035 8.2237 1.4133 10.1667
NCI-H69 GDSC2 4.0205 6.0933 2.4663 3.6914
NCI-H1915 GDSC2 4.0531 6.1472 2.4623 3.6475
COR-L105 GDSC2 4.0661 8.3981 1.3742 10.2441
NCI-H1781 GDSC2 4.0877 6.3949 2.3673 4.1467
NCI-H1048 GDSC2 4.1297 6.2184 2.4788 3.3958
NCI-H1993 GDSC2 4.1414 6.2306 2.4806 3.362
NCI-H1793 GDSC2 4.1528 8.889 1.1969 11.0797
SHP-77 GDSC2 4.2577 7.1193 2.1351 5.1865
LCLC-97TM1 GDSC2 4.2597 11.8878 -0.2068 18.2844
NCI-H2141 GDSC2 4.2855 11.0841 0.2117 16.1674
LCLC-103H GDSC2 4.2871 6.7692 2.321 4.0187
NCI-H290 GDSC2 4.2931 6.3964 2.4989 2.9717
NCI-H196 GDSC2 4.2964 6.674 2.3717 3.7025
NCI-H647 GDSC2 4.3456 6.6062 2.4343 3.248
VMRC-LCD GDSC2 4.3605 9.839 0.8833 12.3694
NCI-H2009 GDSC2 4.3775 6.1899 2.6428 2.0312
NCI-H1436 GDSC2 4.3784 6.7882 2.3702 3.5575
Lu-165 GDSC2 4.3912 6.1634 2.6623 1.9067
LC-2/ad GDSC2 4.4048 6.7328 2.4122 3.268
CAL-12T GDSC2 4.4067 8.7703 1.4403 9.0289
NCI-H2085 GDSC2 4.4397 7.1748 2.2283 4.2677
NCI-H2347 GDSC2 4.4556 8.4101 1.6494 7.6743
NCI-H2227 GDSC2 4.5368 18.568 -3.3138 28.3519
NCI-H3255 GDSC2 4.538 6.4941 2.5979 2.0303
COR-L279 GDSC2 4.5442 6.4022 2.6416 1.7955
NCI-H2122 GDSC2 4.5682 14.795 -1.4119 22.517
NCI-H1105 GDSC2 4.5723 9.0635 1.4146 8.8044
LXF 289 GDSC2 4.6211 8.6629 1.6412 7.364
SW1271 GDSC2 4.641 6.8504 2.4979 2.4064
NCI-H1693 GDSC2 4.6438 6.8182 2.5137 2.3186
HCC78 GDSC2 4.6506 7.0909 2.3958 2.9433
IA-LM GDSC2 4.6606 6.4562 2.6797 1.4567
EMC-BAC-1 GDSC2 4.6626 7.1192 2.39 2.9559
NCI-H2030 GDSC2 4.6786 7.0366 2.4363 2.679
NCI-H82 GDSC2 4.7267 6.1769 2.8263 0.7448
DMS 53 GDSC2 4.7298 7.5405 2.2384 3.6847
DMS 273 GDSC2 4.7607 7.443 2.301 3.2858
NCI-H2444 GDSC2 4.8196 6.1861 2.8635 0.5377
NCI-H1734 GDSC2 4.8272 6.8537 2.5966 1.6527
HCC15 GDSC2 4.8571 8.1516 2.035 4.6106
LOU-NH91 GDSC2 4.8668 7.1413 2.4941 2.1066
NCI-H211 GDSC2 4.8979 7.1439 2.5094 1.9894
NCI-H1650 GDSC2 4.9052 7.1779 2.4987 2.033
NCI-H1755 GDSC2 4.9259 6.9507 2.6057 1.4946
Lu-99A GDSC2 4.9381 7.364 2.4358 2.3056
NCI-H526 GDSC2 4.9546 6.3528 2.8569 0.4729
NCI-H2135 GDSC2 4.9587 6.4762 2.8117 0.6194
RERF-LC-MS GDSC2 4.9947 10.2489 1.1339 9.4947
NCI-H2170 GDSC2 5.0344 6.8495 2.6989 0.9824
PaCa-3 GDSC2 5.0459 7.8219 2.2943 2.8834
A-427 GDSC2 5.0499 18.906 -3.081 26.5809
NCI-H226 GDSC2 5.0601 6.7778 2.7388 0.8064
A-549 GDSC2 5.0899 7.1169 2.617 1.2706
NCI-H2722 GDSC2 5.0966 7.0785 2.6358 1.1843
NCI-H661 GDSC2 5.1043 7.8169 2.3285 2.6242
DMS 79 GDSC2 5.1359 6.9957 2.687 0.9421
NCI-H2803 GDSC2 5.1458 7.137 2.6352 1.1406
NCI-H1838 GDSC2 5.1637 9.3867 1.6525 6.2202
COLO 668 GDSC2 5.2139 7.3146 2.5953 1.2421
NCI-H510A GDSC2 5.2354 7.1477 2.6717 0.919
NCI-H2810 GDSC2 5.2456 7.8793 2.3763 2.2017
NCI-H522 GDSC2 5.2652 7.5467 2.5252 1.4916
NCI-H596 GDSC2 5.2932 11.8056 0.5893 11.8153
NCI-H1573 GDSC2 5.2948 7.1386 2.7012 0.7662
NCI-H1435 GDSC2 5.3302 7.207 2.6901 0.78
IST-SL2 GDSC2 5.3543 8.2749 2.2638 2.6154
PC-14 GDSC2 5.3806 7.3892 2.6414 0.9175
HOP-92 GDSC2 5.3915 7.9945 2.4018 1.9097
Calu-3 GDSC2 5.4262 7.3084 2.6922 0.7072
NCI-H2023 GDSC2 5.4404 7.9002 2.4646 1.5772
NCI-H1568 GDSC2 5.4557 8.3056 2.3034 2.2958
NCI-H2869 GDSC2 5.4809 7.7014 2.5635 1.1318
NCI-H727 GDSC2 5.4825 7.1616 2.7699 0.4409
LC-1/sq GDSC2 5.4862 12.0914 0.5833 11.4359
Ms-1 GDSC2 5.5046 7.4737 2.6623 0.7548
KNS-62 GDSC2 5.5229 7.1177 2.8015 0.3429
NCI-H1341 GDSC2 5.5538 7.0654 2.8318 0.2641
SK-MES-1 GDSC2 5.5581 7.7839 2.5655 1.0606
NCI-H1299 GDSC2 5.5647 11.127 1.0927 8.567
NCI-H810 GDSC2 5.5801 7.0038 2.8629 0.1964
NCI-H841 GDSC2 5.6118 7.4836 2.7029 0.5626
NCI-H1792 GDSC2 5.6265 7.6288 2.6546 0.7017
NCI-H2066 GDSC2 5.6344 7.1009 2.8489 0.2063
HOP-62 GDSC2 5.6387 7.7008 2.6325 0.7658
HCC44 GDSC2 5.6722 7.9091 2.5669 0.9681
NCI-H2172 GDSC2 5.687 7.3007 2.7984 0.2886
SW1573 GDSC2 5.6986 9.6142 1.8661 4.1653
NCI-H1437 GDSC2 5.7 7.6453 2.6786 0.5857
NCI-H1944 GDSC2 5.7229 7.9652 2.5671 0.9305
NCI-H1563 GDSC2 5.7449 7.4806 2.7562 0.3607
NCI-H1623 GDSC2 5.7714 8.5597 2.3534 1.7249
Lu-65 GDSC2 5.8094 7.5642 2.7508 0.3481
NCI-H1666 GDSC2 5.8229 7.8543 2.6507 0.6004
NCI-H1703 GDSC2 5.8357 7.5488 2.7661 0.3053
RERF-LC-KJ GDSC2 5.8541 7.3717 2.8344 0.175
EMC-BAC-2 GDSC2 5.8552 8.0682 2.5839 0.7857
NCI-H2110 GDSC2 5.8637 7.9831 2.6193 0.6704
NCI-H358 GDSC2 5.8696 7.9207 2.6449 0.5924
NCI-H2804 GDSC2 5.8841 8.1761 2.5551 0.8611
LK-2 GDSC2 5.8974 7.6074 2.7684 0.2804
NCI-H2595 GDSC2 5.9119 7.6293 2.7661 0.2803
NCI-H2591 GDSC2 5.9223 12.6003 0.6295 10.3185
RERF-LC-Sq1 GDSC2 5.9225 8.6098 2.4034 1.3824
ChaGo-K-1 GDSC2 5.954 7.5798 2.7986 0.2088
DMS 114 GDSC2 5.9544 7.3459 2.878 0.0988
NCI-H2087 GDSC2 5.962 7.7771 2.7326 0.3325
NCI-H2731 GDSC2 6.0198 7.8423 2.7311 0.3158
NCI-H441 GDSC2 6.0363 8.1178 2.6387 0.5266
NCI-H2818 GDSC2 6.0611 8.1176 2.6484 0.4901
NCI-H2461 GDSC2 6.0727 8.3088 2.583 0.6623
NCI-H520 GDSC2 6.1557 8.1814 2.6618 0.4183
SK-LU-1 GDSC2 6.1741 7.9676 2.7438 0.2451
NCI-H1355 GDSC2 6.1932 8.1455 2.6887 0.3454
NCI-H23 GDSC2 6.209 7.8807 2.7861 0.1698
HARA [Human squamous cell lung carcinoma] GDSC2 6.2106 8.1426 2.6961 0.3243
NCI-H1651 GDSC2 6.3116 8.2581 2.6928 0.2992
NCI-H1648 GDSC2 6.3306 8.4462 2.6336 0.4155
EKVX GDSC2 6.3337 8.6302 2.5686 0.572
NCI-H2228 GDSC2 6.3556 8.9357 2.4645 0.8576
NCI-H3122 GDSC2 6.3915 8.5138 2.6325 0.3957
NCI-H2405 GDSC2 6.6322 8.3626 2.7702 0.1172
⏷ Show the Full List of 182 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 5.6147 7.5334 2.6856 0.6125
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-150 GDSC2 2.3702 8.4237 -0.0599 23.3201
TE-6 GDSC2 3.2916 8.864 0.5256 17.292
TE-1 GDSC2 3.5679 5.4756 2.4426 4.8921
KYSE-180 GDSC2 3.5854 9.5372 0.431 16.936
TE-10 GDSC2 3.6975 5.4329 2.5607 3.831
TE-11 GDSC2 4.0449 6.0585 2.4991 3.4444
OE33 GDSC2 4.1568 7.0805 2.0847 5.7091
KYSE-140 GDSC2 4.2556 7.9024 1.7555 7.4866
OE21 GDSC2 4.5507 10.8907 0.5064 13.9644
EC-GI-10 GDSC2 4.7171 6.9218 2.5087 2.2384
TE-4 GDSC2 5.0129 7.8567 2.2605 3.1106
T.T GDSC2 5.0767 6.8509 2.7175 0.8734
KYSE-520 GDSC2 5.3907 11.2563 0.9181 9.8574
TE-8 GDSC2 5.4102 7.3416 2.6727 0.784
KYSE-270 GDSC2 5.418 7.7808 2.5026 1.4365
COLO 680N GDSC2 5.5733 7.227 2.7816 0.37
KYSE-510 GDSC2 5.5925 7.3696 2.7373 0.4757
KYSE-450 GDSC2 5.6224 6.8788 2.9205 0.1018
TE-9 GDSC2 5.7682 7.4835 2.764 0.334
KYSE-70 GDSC2 5.7791 7.3613 2.811 0.2344
TE-5 GDSC2 5.9779 7.5067 2.832 0.1519
OE19 GDSC2 5.9813 15.4236 -0.6815 16.3538
KYSE-410 GDSC2 6.1987 8.3096 2.6323 0.4709
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Caov-4 GDSC2 2.5417 3.5671 2.3928 8.6361
JHOS-4 GDSC2 2.6082 4.5433 2.0478 10.4141
Caov-3 GDSC2 3.3793 5.0485 2.5059 5.0022
TOV-21G GDSC2 3.4522 5.1441 2.517 4.7297
A2780 GDSC2 3.6855 6.0612 2.2422 5.8488
OVK18 GDSC2 3.8481 7.1359 1.8337 7.9859
OV56 GDSC2 3.9518 5.6792 2.6178 2.9252
DOV13 GDSC2 3.9652 5.8738 2.5341 3.3988
OC 314 GDSC2 4.231 5.9179 2.6805 2.0569
ES-2 GDSC2 4.3394 7.0682 2.2137 4.5495
OVCAR-3 GDSC2 4.3476 6.3576 2.5497 2.5896
RMG-I GDSC2 4.5533 7.2941 2.2441 3.9634
TOV-112D GDSC2 4.6048 6.6117 2.5831 2.0119
TYK-nu GDSC2 4.6399 9.2421 1.3752 8.884
IGROV-1 GDSC2 4.7609 13.8271 -0.7849 19.5754
EFO-27 GDSC2 4.8505 7.3306 2.4026 2.6005
JHOS-2 GDSC2 4.9123 6.716 2.6958 1.109
OVISE GDSC2 4.939 11.7729 0.3565 13.819
OVCAR-8 GDSC2 4.9497 9.0652 1.6671 6.5439
OAW42 GDSC2 4.9545 6.3562 2.8555 0.477
FU-OV-1 GDSC2 5.0836 7.3795 2.5051 1.7819
OVCAR-5 GDSC2 5.4012 8.9864 1.9774 4.027
EFO-21 GDSC2 5.5161 7.4497 2.6763 0.7011
SK-OV-3 GDSC2 5.7183 7.3045 2.8086 0.2575
OAW28 GDSC2 5.7485 8.3142 2.4416 1.3817
OVKATE GDSC2 5.8796 7.4848 2.8046 0.2179
Kuramochi GDSC2 6.0373 7.9547 2.6978 0.3815
OVTOKO GDSC2 6.1026 12.6167 0.737 9.4266
OV-90 GDSC2 6.1223 7.9658 2.7256 0.2938
OVCAR-4 GDSC2 6.6492 17.3396 -1.1453 16.8695
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PL4 GDSC2 2.5028 3.4587 2.3872 8.8381
HuP-T3 GDSC2 3.3847 4.9627 2.5532 4.6876
HPAC GDSC2 3.8675 8.1454 1.3484 10.9078
KP-1N GDSC2 4.0245 7.8933 1.592 9.0307
DAN-G GDSC2 4.1002 6.4339 2.357 4.1824
Panc 10.05 GDSC2 4.1101 7.3366 1.9275 6.7746
HuP-T4 GDSC2 4.1679 6.6185 2.3142 4.2987
KP-4 GDSC2 4.2566 5.7999 2.7479 1.6531
Panc 03.27 GDSC2 4.4117 6.6251 2.466 2.9504
PaTu 8902 GDSC2 4.4162 7.9652 1.8368 6.6401
Panc 02.03 GDSC2 4.7641 6.6431 2.6534 1.4581
QGP-1 GDSC2 4.8087 11.7698 0.2639 14.5993
PaTu 8988t GDSC2 4.8618 10.4717 0.9348 10.8996
CFPAC-1 GDSC2 5.005 6.6321 2.7714 0.7286
SU.86.86 GDSC2 5.013 6.2159 2.9301 0.2447
YAPC GDSC2 5.1035 6.6168 2.8191 0.5015
AsPC-1 GDSC2 5.3458 7.549 2.5624 1.2553
Capan-1 GDSC2 5.3489 7.1101 2.735 0.6172
MIA PaCa-2 GDSC2 5.4245 6.7811 2.8838 0.2024
KP-2 GDSC2 5.447 7.2019 2.7409 0.5416
BxPC-3 GDSC2 5.4599 7.7397 2.5387 1.2483
Hs 766T GDSC2 5.5683 7.5194 2.6718 0.683
SUIT-2 GDSC2 5.5896 7.204 2.7961 0.3292
HPAF-II GDSC2 5.6072 7.536 2.6816 0.629
PSN1 GDSC2 5.643 7.279 2.7896 0.3236
Panc 04.03 GDSC2 5.8807 7.4072 2.8317 0.1731
Capan-2 GDSC2 6.0268 7.9038 2.712 0.3539
KP-3 GDSC2 6.0379 8.0202 2.6746 0.4354
SW1990 GDSC2 6.132 8.1657 2.6584 0.4357
Panc 08.13 GDSC2 6.1343 8.1135 2.6779 0.3898
MZ-PC-1 GDSC2 6.6312 8.8021 2.6199 0.3421
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC2 4.8104 7.0427 2.5066 2.1192
MSTO-211H GDSC2 5.0206 7.4746 2.432 2.2147
NCI-H2052 GDSC2 5.6109 12.3586 0.5394 11.404
NCI-H2452 GDSC2 5.6366 7.9501 2.5352 1.1121
NCI-H28 GDSC2 5.9149 7.6547 2.7582 0.2951
IST-Mes1 GDSC2 6.1571 7.9108 2.7573 0.2263
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2 2.0752 3.6693 1.8528 13.712
NCI-H660 GDSC2 3.1357 4.4518 2.5951 5.1734
PC-3 GDSC2 5.4035 8.6597 2.1232 3.2599
VCaP GDSC2 5.52 7.0733 2.8163 0.3098
DU145 GDSC2 6.4633 8.3802 2.7054 0.2358
22Rv1 GDSC2 6.5702 8.7373 2.6201 0.3608
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 5.7433 7.3303 2.8088 0.2493
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DJM-1 GDSC2 2.4712 4.2854 2.0264 11.0663
RPMI-7951 GDSC2 2.8533 4.528 2.2946 8.0084
CHL-1 GDSC2 2.9361 4.4737 2.3996 7.0674
MZ-MEL-2 GDSC2 3.0452 5.5879 1.9508 9.5179
CP50-MEL-B GDSC2 3.0753 4.3176 2.6061 5.3039
A2058 GDSC2 3.1386 4.334 2.656 4.7815
IGR-1 GDSC2 3.2506 4.6912 2.5769 4.9286
SK-MEL-28 GDSC2 3.3416 4.6972 2.6506 4.1935
SK-MEL-30 GDSC2 3.3888 4.6668 2.7044 3.7199
A-375 GDSC2 3.4769 4.6801 2.7673 3.0862
Mel Ho GDSC2 3.478 4.678 2.7691 3.072
LOX-IMVI GDSC2 3.5944 5.3252 2.5373 4.2299
A101D GDSC2 3.6122 6.3451 2.045 7.2763
G-mel GDSC2 3.7676 6.051 2.3086 5.2302
IPC-298 GDSC2 3.8889 8.0791 1.3977 10.5549
SK-MEL-2 GDSC2 3.9173 7.0686 1.9186 7.2876
M14 GDSC2 3.9937 6.8643 2.0746 6.1416
SK-MEL-3 GDSC2 4.05 5.8793 2.5872 2.912
Hs 940.T GDSC2 4.2523 7.1911 2.097 5.4276
COLO 800 GDSC2 4.276 6.6034 2.3918 3.6237
COLO 829 GDSC2 4.2834 6.758 2.3239 4.0087
VMRC-MELG GDSC2 4.3112 5.9696 2.7033 1.808
IGR-37 GDSC2 4.436 5.9678 2.7715 1.2889
COLO 792 GDSC2 4.4529 6.9694 2.3325 3.6384
HMV-II GDSC2 4.5686 7.879 1.9797 5.4746
451Lu GDSC2 4.5722 6.7269 2.514 2.4248
SK-MEL-5 GDSC2 4.6132 7.9514 1.9745 5.417
WM793 GDSC2 4.6481 12.755 -0.3401 17.9086
CP66-MEL GDSC2 4.6563 6.7262 2.5611 2.0533
LB373-MEL-D GDSC2 4.7011 5.952 2.9026 0.4854
Mel JuSo GDSC2 4.7203 11.7392 0.2142 15.0637
Hs 938.T GDSC2 4.724 6.2858 2.7814 0.929
WM278 GDSC2 4.8011 7.7322 2.1936 3.8146
G-361 GDSC2 4.8541 8.8938 1.6861 6.6224
A-431 GDSC2 4.8742 6.8663 2.6152 1.5096
SK-MEL-31 GDSC2 4.8749 12.8082 -0.1974 16.6923
WM35 GDSC2 4.8954 7.3553 2.4164 2.464
MZ-MEL-7 GDSC2 4.9104 6.8583 2.6364 1.3715
A-388 GDSC2 5.0163 7.4683 2.4324 2.2181
COLO 783 GDSC2 5.0567 6.5866 2.8111 0.5557
MMAc-SF GDSC2 5.1179 6.4649 2.8808 0.3201
LB2518-MEL GDSC2 5.1812 6.7081 2.8167 0.4645
MeWo GDSC2 5.1844 10.6922 1.0496 9.5647
WM115 GDSC2 5.1915 6.4263 2.9224 0.199
WT2-iPS GDSC2 5.3735 6.5561 2.9429 0.1181
GAK GDSC2 5.374 6.796 2.8599 0.267
UACC-62 GDSC2 5.4552 6.7862 2.8931 0.1771
SK-MEL-24 GDSC2 5.5813 7.074 2.8389 0.2408
SK-MEL-1 GDSC2 5.5904 6.8117 2.932 0.0934
RVH-421 GDSC2 5.7309 7.1709 2.8594 0.1645
COLO 679 GDSC2 5.7789 7.3099 2.8288 0.2028
SH-4 GDSC2 5.9084 7.8417 2.6891 0.455
UACC-257 GDSC2 6.0845 12.6113 0.7282 9.5055
IST-MEL1 GDSC2 6.2581 8.1051 2.7266 0.2527
WM1552C GDSC2 6.3806 7.8741 2.847 0.0754
HT-144 GDSC2 7.3593 17.1482 -0.5859 13.283
EquiPSC Line K2 GDSC2 4.9904 8.3241 2.0366 4.3687
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 3.177 7.0268 1.3474 12.8648
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-401 GDSC2 2.7686 5.447 1.7692 11.5623
Rh41 GDSC2 3.2608 13.0692 -1.6027 26.7332
KYM-1 GDSC2 3.2663 4.3854 2.7431 3.8295
TE 441.T GDSC2 3.276 5.8606 2.0142 8.4119
G-402 GDSC2 3.4783 8.9962 0.614 16.2521
STS-0421 GDSC2 3.8474 6.2908 2.2494 5.4061
Hs 633.T GDSC2 3.9962 6.017 2.4865 3.6205
HT-1080 GDSC2 4.0234 5.5985 2.7016 2.2954
EW-8 GDSC2 4.0868 6.7952 2.174 5.3205
A-204 GDSC2 4.3209 6.9449 2.26 4.3122
RKN GDSC2 4.4984 6.1516 2.7255 1.4355
RD GDSC2 4.527 6.9135 2.4034 3.1054
Rh30 GDSC2 4.6343 7.2888 2.2962 3.5242
SW982 GDSC2 4.8578 7.2213 2.4545 2.3202
VA-ES-BJ GDSC2 4.9793 7.3578 2.4604 2.1269
SW684 GDSC2 5.2195 6.3885 2.9457 0.1487
GCT GDSC2 5.4863 16.2227 -1.4256 20.3867
MFH-ino GDSC2 5.4995 7.3063 2.7234 0.5643
SW872 GDSC2 5.5854 7.2518 2.7773 0.3755
MES-SA GDSC2 5.616 6.6521 2.9932 0.0364
SK-UT-1 GDSC2 5.9507 7.6302 2.78 0.2423
SK-LMS-1 GDSC2 6.3193 7.9555 2.7991 0.1323
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC2 1.5654 2.9072 1.5002 17.9624
Hs 746.T GDSC2 2.9315 3.8699 2.6801 5.3624
HGC-27 GDSC2 3.4424 4.8235 2.669 3.7966
AGS GDSC2 3.4804 8.9125 0.6576 16.0044
GCIY GDSC2 3.4855 5.1263 2.5522 4.4181
SK-GT-2 GDSC2 3.664 6.7987 1.8597 8.2997
SCH GDSC2 3.8734 6.8128 2.0121 6.8162
ECC12 GDSC2 3.8932 6.1264 2.3625 4.6008
SNU-1 GDSC2 4.0033 5.7835 2.6021 2.9154
Fu97 GDSC2 4.295 7.7078 1.8774 6.6605
23132/87 GDSC2 4.2972 6.1116 2.6316 2.2185
ECC10 GDSC2 4.3922 7.8282 1.8863 6.3953
MKN7 GDSC2 4.5285 6.6317 2.5316 2.3975
MKN45 GDSC2 4.8211 5.8714 2.9803 0.204
IM95 GDSC2 4.893 8.5455 1.8745 5.4607
NCI-N87 GDSC2 4.9803 18.724 -3.0444 26.641
SNU-5 GDSC2 5.0131 6.3946 2.8651 0.4145
SNU-16 GDSC2 5.2763 6.5313 2.9168 0.1842
RERF-GC-1B GDSC2 5.355 10.7768 1.1222 8.8163
RF-48 GDSC2 5.5632 7.319 2.7442 0.4712
TGBC11TKB GDSC2 5.5685 7.1572 2.8047 0.3175
NUGC-4 GDSC2 5.6326 7.5878 2.6726 0.6418
KATO III GDSC2 5.6363 7.1702 2.8255 0.2499
OCUM-1 GDSC2 5.6819 7.799 2.6133 0.801
MKN1 GDSC2 5.7231 7.2788 2.8193 0.2353
NUGC-3 GDSC2 5.9379 13.4842 0.2207 12.3321
TMK-1 GDSC2 5.9654 7.727 2.7515 0.2922
MKN28 GDSC2 6.3173 8.3756 2.6537 0.3765
SNG-M GDSC2 5.4555 7.4774 2.6399 0.8669
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BHT-101 GDSC2 3.3035 4.4686 2.7332 3.7816
CAL-62 GDSC2 3.3335 5.6082 2.1884 7.1427
KMH-2 GDSC2 3.3796 4.8305 2.6151 4.3105
HTC-C3 GDSC2 3.8371 8.2092 1.2932 11.3204
FTC-133 GDSC2 4.2054 9.4707 0.9492 12.3831
K5 GDSC2 4.5069 7.2258 2.247 4.0322
ASH-3 GDSC2 4.5278 6.1045 2.7607 1.23
B-CPAP GDSC2 4.5761 7.9475 1.9522 5.6216
8505C GDSC2 4.9327 7.5706 2.3423 2.797
TT2609-C02 GDSC2 4.9855 10.3018 1.1022 9.6923
CGTH-W-1 GDSC2 5.1607 6.791 2.7771 0.5999
ML-1 [Human leukemia] GDSC2 5.2781 6.852 2.8025 0.4537
8305C GDSC2 5.2952 6.7089 2.8611 0.2939
WRO GDSC2 5.4401 7.1197 2.7685 0.4657
IHH-4 GDSC2 5.8761 7.2744 2.8751 0.1144
TT GDSC2 6.0813 7.6661 2.8142 0.1561
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HO-1-u-1 GDSC2 2.2772 4.2065 1.8598 12.8245
FaDu GDSC2 2.7218 3.6122 2.5699 6.8554
JHU-011 GDSC2 3.0931 5.1123 2.2296 7.6113
OSC-19 GDSC2 3.3735 10.7631 -0.3558 21.461
HSC-3 GDSC2 3.5865 5.3823 2.503 4.4647
KOSC-2 GDSC2 3.7636 6.0147 2.3236 5.1469
Detroit 562 GDSC2 3.8809 6.1395 2.3475 4.7216
CAL-27 GDSC2 3.9819 5.9006 2.5325 3.3738
PCI-15A GDSC2 3.9971 5.8572 2.5632 3.1592
BICR 31 GDSC2 4.0822 6.0685 2.5188 3.2525
SAS GDSC2 4.1064 6.298 2.426 3.7562
JHU-022 GDSC2 4.1457 7.2857 1.9775 6.3871
BICR 10 GDSC2 4.2436 6.2929 2.5163 2.9617
JHU-029 GDSC2 4.7169 7.6618 2.1749 4.0653
SKN-3 GDSC2 4.7686 7.4144 2.3186 3.1765
PCI-04B GDSC2 4.7707 7.5458 2.2603 3.4939
HSC-2 GDSC2 4.8441 7.5906 2.2831 3.2498
SCC-15 GDSC2 4.9558 7.88 2.2175 3.4293
CAL-33 GDSC2 5.0556 7.3005 2.5242 1.7251
BB49-HNC GDSC2 5.0856 7.5304 2.4421 2.0814
BICR 22 GDSC2 5.1634 6.9147 2.7309 0.7567
SCC-9 GDSC2 5.2025 7.9911 2.3056 2.6069
Ca9-22 GDSC2 5.2278 7.3054 2.6055 1.1869
NCI-H3118 GDSC2 5.2355 7.7052 2.4448 1.888
KON GDSC2 5.2388 7.6349 2.4758 1.7408
BB30-HNC GDSC2 5.2392 10.9209 0.977 9.8499
PCI-06A GDSC2 5.2508 9.0189 1.8752 4.8229
HO-1-N-1 GDSC2 5.3036 7.1147 2.7142 0.7153
LB771-HNC GDSC2 5.3509 11.8387 0.6128 11.5678
BHY GDSC2 5.4491 7.3213 2.6969 0.6768
SCC-25 GDSC2 5.4677 7.614 2.592 1.0332
PCI-30 GDSC2 5.5218 7.4679 2.6718 0.7123
SCC-4 GDSC2 5.5667 7.1148 2.8192 0.2863
UPCI-SCC-090 GDSC2 5.6029 7.6016 2.6551 0.7149
OSC-20 GDSC2 5.7064 7.5487 2.7167 0.476
BICR 78 GDSC2 5.9328 8.2089 2.5631 0.8041
HSC-4 GDSC2 6.0557 14.7111 -0.2869 14.474
PE/CA-PJ15 GDSC2 6.112 7.9326 2.7334 0.2819
SAT [Human HNSCC] GDSC2 6.3824 16.1196 -0.741 15.7769
DOK GDSC2 6.6503 8.8495 2.6103 0.3548
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 GDSC2 2.9001 4.3282 2.435 6.9755
BFTC-905 GDSC2 3.1095 4.6278 2.4845 5.9539
CAL-29 GDSC2 3.1757 4.6156 2.5496 5.3325
KU-19-19 GDSC2 3.3463 4.9454 2.5305 4.9407
TCCSUP GDSC2 3.8349 5.74 2.5091 3.8322
SW780 GDSC2 4.1123 6.134 2.5074 3.2611
647V GDSC2 4.1388 6.8295 2.1934 5.0889
5637 GDSC2 4.3838 6.3273 2.5848 2.3359
639V GDSC2 4.4916 11.571 0.127 16.0679
RT-4 GDSC2 5.3408 14.113 -0.4976 16.9645
SW1710 GDSC2 5.4452 7.1088 2.7745 0.4467
RT-112 GDSC2 5.4584 7.0163 2.8133 0.3413
UM-UC-3 GDSC2 5.7393 7.3252 2.809 0.25
J82 GDSC2 5.9307 7.9694 2.6513 0.5435
HT-1376 GDSC2 6.1407 8.1371 2.672 0.4008
T24 GDSC2 6.2368 8.5355 2.565 0.628
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NT2-D1 GDSC2 2.7329 4.0471 2.3991 7.8164
NEC8 GDSC2 2.7336 3.5233 2.6155 6.5449
PA-1 GDSC2 3.2113 7.6738 1.0531 14.5311
C-33 A GDSC2 3.3983 5.2035 2.444 5.3407
TC-YIK GDSC2 3.4953 5.1329 2.5566 4.3646
JHOS-3 GDSC2 3.544 5.0623 2.6292 3.7811
SW954 GDSC2 3.6088 5.3669 2.5276 4.2544
OV17R GDSC2 3.6958 5.9593 2.3003 5.4588
HeLa GDSC2 3.8676 6.6096 2.1077 6.2364
NCC-IT GDSC2 3.877 6.0678 2.3796 4.5327
JAR GDSC2 3.8829 5.5103 2.6526 2.8576
DSH1 GDSC2 3.9162 6.5713 2.162 5.7842
MS751 GDSC2 4.0748 6.084 2.5066 3.3394
JEG-3 GDSC2 4.2176 6.109 2.5853 2.6131
SiHa GDSC2 4.2825 5.8551 2.7379 1.6673
C-4-I GDSC2 4.5593 6.5364 2.5911 2.0352
CAL-39 GDSC2 4.8527 6.9019 2.5893 1.657
OMC-1 [Human cervical carcinoma] GDSC2 4.8628 6.7662 2.6513 1.3563
OVCA420 GDSC2 4.9015 8.4002 1.9473 5.0291
SiSo GDSC2 5.026 8.2402 2.0959 3.9807
HT-3 GDSC2 5.1778 7.5498 2.481 1.7855
UWB1.289 GDSC2 5.1872 7.8603 2.354 2.3852
SKN GDSC2 5.261 7.4965 2.5437 1.4153
HEC-1 GDSC2 5.3682 7.4695 2.6044 1.0677
PWR-1E GDSC2 5.371 8.1672 2.3187 2.3256
BPH-1 GDSC2 5.3752 9.6892 1.6432 5.8901
HEY GDSC2 5.3846 7.9321 2.4243 1.8145
SW756 GDSC2 5.4484 7.1357 2.766 0.4687
SKG-IIIa GDSC2 5.4489 7.127 2.7693 0.4591
DoTc2 4510 GDSC2 5.5388 7.3022 2.7407 0.4932
LB831-BLC GDSC2 5.6932 8.3078 2.4187 1.5257
OVCA433 GDSC2 5.7927 8.4558 2.4054 1.4885
SW962 GDSC2 5.8702 7.3023 2.8636 0.1299
PEO1 GDSC2 6.2264 8.4112 2.6063 0.5237
ACC-OV7 GDSC2 6.4696 9.5141 2.2918 1.3637
KGN GDSC2 6.5106 9.0305 2.492 0.6924
Ca Ski GDSC2 6.5446 8.8824 2.559 0.5043
OVMIU GDSC2 6.5967 9.0701 2.5114 0.5996
ME-180 GDSC2 6.6933 9.3334 2.4533 0.7076
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 P22077 inhibits LPS-induced inflammatory response by promoting K48-linked ubiquitination and degradation of TRAF6. Aging (Albany NY). 2020 Jun 9;12(11):10969-10982.