Details of the Drug

General Information of Drug (ID: DMDGKFV)

• Drug Name: 4-Hydroxy-pentanoic acid
• Synonyms: 4-Hydroxypentanoic acid; 4-Hydroxyvaleric acid; 4-hydroxy-pentanoic acid; gamma-Hydroxyvaleric acid; 13532-37-1; 4-hydroxy-valeric acid; Pentanoic acid, 4-hydroxy-; 103712-26-1; Pentanoic acid, 4-hydroxy-, (S)-; EINECS 236-884-1; ACMC-20m6jh; AC1Q5VUF; Pentanoic acid,4-hydroxy-; AC1L3FK5; AC1Q2BV5; SCHEMBL27394; CHEMBL169219; CTK4B9757; FMHKPLXYWVCLME-UHFFFAOYSA-N; MolPort-006-120-502; LMFA01050009; AKOS008148154; MCULE-6352217997; TX-017030

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 118.13
  Logarithm of the Partition Coefficient (xlogp); -0.2
  Rotatable Bond Count (rotbonds); 3
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C5H10O3
  IUPAC Name: 4-hydroxypentanoic acid
  Canonical SMILES: CC(CCC(=O)O)O
  InChI: InChI=1S/C5H10O3/c1-4(6)2-3-5(7)8/h4,6H,2-3H2,1H3,(H,7,8)
  InChIKey: FMHKPLXYWVCLME-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 114539
  CAS Number: 13532-37-1
  TTD ID: D07QSV
  VARIDT ID: DR01080

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Gamma-hydroxybutyrate receptor (SLC52A2)	TT6TKEN	S52A2_HUMAN	Inhibitor	[1]

References

• [1] Analogues of gamma-hydroxybutyric acid. Synthesis and binding studies. J Med Chem. 1988 May;31(5):893-7.