Details of the Drug

General Information of Drug (ID: DMDIOAR)

Drug Name
Treosulfan
Synonyms
Tresulfan; Dimesyl-meso-erythritol; Erythritol, 1,4-dimethanesulfonate; Erythritol, dimesyl-, meso-; Dihydroxymyleran; Dihydroxybusulfan; 1,4-Di(methanesulfonate)erythritol; NSC 94160; L-Threityl dimesylate; Erythritol, 1,4-bis(methanesulfonate); Threitol-1,4-bismethanesulfonate, meso-; CB 40069; 1,4-Bis(methanesulfonyloxy)-2,3-butanediol; 1,4-Bis(methylsulfonyloxy)threitol; Threitol 1,4-bis(methanesulfonate); ERYTHRITOL, 1,4-DIMETHANESULFONATE, (meso)-; NCGC00181153-01; L-Threitol 1,4-dimethanesulfonate
Indication
Disease Entry ICD 11 Status REF
Melanoma 2C30 Approved [1]
ATC Code
L01AB02: Treosulfan
L01AB: Alkyl sulfonates
L01A: ALKYLATING AGENTS
L01: ANTINEOPLASTIC AGENTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C6H14O8S2
Canonical SMILES
CS(=O)(=O)OCC(C(COS(=O)(=O)C)O)O
InChI
InChI=1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3/t5-,6-/m0/s1
InChIKey
YCPOZVAOBBQLRI-WDSKDSINSA-N
Cross-matching ID
PubChem CID
9882105
ChEBI ID
CHEMBL82557
CAS Number
299-75-2
UNII
CO61ER3EPI
DrugBank ID
DB11678
TTD ID
D04YPN
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Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8281).