Details of the Drug

General Information of Drug (ID: DMDIOAR)

Drug Name

Treosulfan

Synonyms

Tresulfan; Dimesyl-meso-erythritol; Erythritol, 1,4-dimethanesulfonate; Erythritol, dimesyl-, meso-; Dihydroxymyleran; Dihydroxybusulfan; 1,4-Di(methanesulfonate)erythritol; NSC 94160; L-Threityl dimesylate; Erythritol, 1,4-bis(methanesulfonate); Threitol-1,4-bismethanesulfonate, meso-; CB 40069; 1,4-Bis(methanesulfonyloxy)-2,3-butanediol; 1,4-Bis(methylsulfonyloxy)threitol; Threitol 1,4-bis(methanesulfonate); ERYTHRITOL, 1,4-DIMETHANESULFONATE, (meso)-; NCGC00181153-01; L-Threitol 1,4-dimethanesulfonate

Indication

Disease Entry	ICD 11	Status	REF
Melanoma	2C30	Approved	[1]
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ATC Code

L01AB02: Treosulfan

L01AB: Alkyl sulfonates

L01A: ALKYLATING AGENTS

L01: ANTINEOPLASTIC AGENTS

L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C6H14O8S2
Canonical SMILES: CS(=O)(=O)OCC(C(COS(=O)(=O)C)O)O
InChI: 1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3/t5-,6-/m0/s1
InChIKey: YCPOZVAOBBQLRI-WDSKDSINSA-N

Cross-matching ID

PubChem CID: 9882105
ChEBI ID: CHEBI:82557
CAS Number: 299-75-2
UNII: CO61ER3EPI
DrugBank ID: DB11678
TTD ID: D04YPN

Combinatorial Drugs (CBD)

Click to Jump to the Detailed CBD Information of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8281).