Details of the Drug

General Information of Drug (ID: DMDJH2L)

Drug Name
BMS 536924
Synonyms
BMS-536924; BMS 536924; BMS536924; UNII-40E3AZG1MX; 4-[[(2S)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-3-[7-methyl-5-(4-morpholinyl)-1H-benzimidazol-2-yl]-2(1H)-pyridinone; 40E3AZG1MX; CHEMBL401930; CS-0117; HY-10262; MLS006011171; SCHEMBL4132577; SCHEMBL15974144; BDBM27879; BCP02116; ZINC6718468; 2278AH; s1012; ABP000159; ZINC140935730; AKOS024458339; AKOS025149514; SB19378; RL03740; KIN0000061; NCGC00346460-05; NCGC00346460-02; SMR004702940; BMS-536924/BMS536924; A2238; X5078; SW218124-2; S-7752
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski):
0		 Molecular Weight 479.965
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 6
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 6
Chemical Identifiers
Formula
C25H26ClN5O3
IUPAC Name
4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one
Canonical SMILES
CC1=CC(=CC2=C1N=C(N2)C3=C(C=CNC3=O)NCC(C4=CC(=CC=C4)Cl)O)N5CCOCC5
InChI
InChI=1S/C25H26ClN5O3/c1-15-11-18(31-7-9-34-10-8-31)13-20-23(15)30-24(29-20)22-19(5-6-27-25(22)33)28-14-21(32)16-3-2-4-17(26)12-16/h2-6,11-13,21,32H,7-10,14H2,1H3,(H,29,30)(H2,27,28,33)/t21-/m1/s1
InChIKey
ZWVZORIKUNOTCS-OAQYLSRUSA-N
Cross-matching ID
PubChem CID
135440466
ChEBI ID
CHEBI:91454
CAS Number
468740-43-4
VARIDT ID
DR01619

Molecular Interaction Atlas of This Drug


Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Gene/Protein Processing [2]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [2]
Insulin-like growth factor 1 receptor (IGF1R) OTXJIF13 IGF1R_HUMAN Post-Translational Modifications [2]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Post-Translational Modifications [2]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Post-Translational Modifications [2]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Post-Translational Modifications [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 3.4863 5.3982 2.4174 5.2669
EW-1 GDSC1; GDSC2 -0.848 3.6411 -1.3198 43.1813
EW-7 GDSC1; GDSC2 -0.2536 3.8165 -0.7256 37.8184
SK-ES-1 GDSC1; GDSC2; CTRP2 -0.1839 6.0449 -0.9241 37.8694
ES1 GDSC1; GDSC2 -0.0575 4.2923 -0.6703 36.5239
NOS-1 [Human HNSCC] GDSC1; GDSC2 0.2978 4.243 -0.269 33.0416
EW-16 GDSC1; GDSC2 0.3726 7.4461 -1.5199 37.0062
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 0.3973 4.1012 0.2136 32.6019
ES8 GDSC1; GDSC2 0.5476 5.506 -0.4917 32.7337
HuO9 GDSC1; GDSC2 0.8972 6.2198 -0.4377 30.8836
EW-3 GDSC1; GDSC2 0.9829 7.4589 -0.9157 32.3624
ES4 GDSC1; GDSC2 1.1022 6.136 -0.1917 28.9029
EW-22 GDSC1; GDSC2 1.1134 5.8121 -0.0364 28.135
ES5 GDSC1; GDSC2 1.1221 5.7213 0.0123 27.8654
EW-11 GDSC1; GDSC2 1.1424 7.0537 -0.5697 30.3516
SJSA-1 GDSC1; GDSC2; CTRP2 1.3509 5.9359 0.7799 27.6218
A-673 GDSC1; GDSC2; CTRP2 1.357 6.4241 0.6204 28.1429
ES6 GDSC1; GDSC2 1.5132 6.152 0.2155 25.2072
CHSA0108 GDSC1; GDSC2 1.5505 4.9251 0.7991 21.9291
SK-N-MC CTRP2 1.5738 7.8492 0.3037 28.5182
TC71 CTRP2 1.7357 10.0045 -0.465 30.3399
SaOS-2 GDSC1; GDSC2; CTRP2 1.8042 7.4296 0.7173 26.4593
CHSA0011 GDSC1; GDSC2 1.8458 4.4602 1.3027 17.8367
MHH-ES-1 GDSC1; GDSC2; CTRP2 2.1022 5.9062 1.6054 22.4212
U2OS GDSC1; GDSC2; CTRP1 2.1793 4.6896 2.0287 26.2174
NY GDSC1; GDSC2 2.3128 3.8641 2.0365 11.6478
SK-PN-DW GDSC1; GDSC2 2.3449 9.3435 -0.5373 25.5847
CHSA8926 GDSC1; GDSC2 2.5044 4.1245 2.1307 10.314
MG-63 GDSC1; GDSC2; CTRP2 2.5192 6.2847 1.9228 20.0361
EW-24 GDSC1; GDSC2 2.5667 5.8099 1.4036 14.5072
HuO-3N1 GDSC1; GDSC2 2.7262 5.321 1.791 11.5722
EW-18 GDSC1; GDSC2 2.7857 9.8763 -0.4121 23.5505
CAL-72 GDSC1; GDSC2 2.8602 5.1309 2.0088 9.7603
EW-12 GDSC1; GDSC2 2.9914 6.7317 1.3343 13.5204
H-EMC-SS GDSC1; GDSC2 3.0522 5.3881 2.0563 8.8326
ES7 GDSC1; GDSC2 3.0585 6.4398 1.5384 12.0545
HOS GDSC1; GDSC2; CTRP2 3.1187 5.8586 2.7225 15.3246
TC-71 GDSC1; GDSC2 3.6131 6.0835 2.1756 6.4531
CADO-ES1 GDSC1; GDSC2 3.6541 5.4722 2.5095 4.2551
U-CH2 GDSC2 4.0108 7.5207 1.7653 8.0045
CAL-78 GDSC1; GDSC2; CTRP2 4.0441 6.2741 3.5455 9.6089
SW1353 CTRP2 4.3434 9.262 1.767 10.4487
Hs 888.T CTRP2 4.4023 9.7543 2.2337 14.0857
Hs 822.T CTRP2 5.1484 8.4342 3.5459 7.0979
EW-13 GDSC1; GDSC2 6.2967 11.3214 1.4449 5.4468
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 218 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 2.9666 5.8719 2.5535 16.3945
JK1 CTRP2 2.9824 5.2526 2.767 15.5632
JM1 GDSC1; GDSC2; CTRP2 3.6666 7.8155 2.4712 14.8435
NCI-H929 GDSC1; GDSC2; CTRP2 -2.8315 -0.449 -2.8349 50.0165
MOLM-13 GDSC1; GDSC2; CTRP2 -2.3085 0.3329 -2.3195 46.3033
MV4-11 GDSC1; GDSC2; CTRP2 -2.0753 0.7535 -2.0843 48.4523
A4/Fukuda GDSC1; GDSC2; CTRP2 -1.7668 2.7106 -1.8955 46.5693
MM1.S GDSC2; CTRP2 -1.7157 0.5838 -1.7184 46.0578
KMS-11 GDSC1; GDSC2; CTRP2; CTRP1 -1.4648 4.3031 -1.8484 44.9985
KMS-34 CTRP2 -1.1603 1.4348 -1.171 42.3888
ATN-1 GDSC1; GDSC2 -1.0625 4.4435 -1.8102 45.4529
NK-92MI GDSC1; GDSC2 -0.851 2.8972 -1.1236 42.7336
OCI-AML-5 GDSC1; CTRP2 -0.7722 2.5442 -0.8285 39.9419
KMS-26 CTRP2 -0.7133 2.3498 -0.7526 39.5039
OPM-2 GDSC1; GDSC2; CTRP2 -0.6864 1.206 -0.6883 39.2133
PL21 CTRP2; CTRP1 -0.6522 3.9191 -0.8871 39.6156
ALL-PO GDSC1; GDSC2 -0.6394 2.9375 -0.9026 40.7221
Karpas-620 GDSC1; GDSC2; CTRP2 -0.5952 2.3926 -0.6328 38.7163
OCI-M1 GDSC1; GDSC2; CTRP2 -0.377 1.1022 -0.3774 37.1509
EoL-1 GDSC1; GDSC2; CTRP2 -0.2556 2.0292 -0.2664 36.3778
PL-21 GDSC1; GDSC2 -0.2507 6.2404 -1.6333 40.3694
AML-193 CTRP2 -0.235 2.4246 -0.2616 36.2912
F-36P CTRP2 -0.2312 3.0425 -0.3066 36.4181
Pfeiffer CTRP2 -0.1349 2.7975 -0.1827 35.6935
Mono-Mac-6 GDSC1; GDSC2; CTRP2 -0.1177 4.2549 -0.3742 36.2056
M-07e CTRP2 -0.0974 4.6701 -0.4442 36.3278
BONNA-12 GDSC2 0.0123 3.8232 -0.4384 35.249
L-1236 GDSC1; GDSC2 0.0477 4.0039 -0.4584 35.1403
ML-2 GDSC1; GDSC2 0.134 5.3829 -0.8765 36.2284
ALL-SIL GDSC1; GDSC2 0.1485 3.3262 -0.1425 33.2473
KMS-28BM CTRP2 0.1955 4.3135 -0.0464 34.1137
Ki-JK CTRP2 0.2333 5.4994 -0.5507 30.8953
KMS-20 CTRP2 0.299 3.5936 0.1896 33.0129
L-363 GDSC1; GDSC2; CTRP2 0.314 5.7297 -0.2838 34.3968
Kasumi-1 GDSC1; GDSC2; CTRP2 0.4018 2.7554 0.378 32.0496
KMS-18 CTRP2 0.411 2.4785 0.3996 31.9476
SEM CTRP2 0.4297 4.8865 0.0777 32.9205
SKM-1 GDSC1; GDSC2; CTRP2; CTRP1 0.5352 3.2683 0.4785 31.2722
OCI-Ly7 GDSC1; GDSC2 0.5861 3.4846 0.2902 28.967
SU-DHL-1 GDSC1; GDSC2; CTRP2 0.643 1.9512 0.6399 25.2067
SET-2 CTRP2 0.6959 2.9534 0.6708 30.0983
HuT 78 CTRP2 0.7376 5.6997 0.187 31.5409
OCI-AML-2 GDSC1; GDSC2; CTRP2 0.7842 4.3998 0.5745 30.1299
SUP-M2 GDSC1; GDSC2; CTRP2 0.8244 1.551 0.8244 29.1602
NB4 GDSC1; GDSC2; CTRP2 0.9572 3.7806 0.8666 28.5817
A3/Kawakami GDSC1; GDSC2; CTRP2 0.9971 2.5085 0.9941 28.022
KMS-12-BM GDSC1; GDSC2; CTRP2 1.0378 5.7376 0.5023 29.5449
HAL-01 GDSC1; GDSC2 1.0738 5.6776 -0.0182 28.2229
SR GDSC1; GDSC2; CTRP2 1.1262 2.8302 1.1182 27.18
GR-ST GDSC1; GDSC2 1.1518 6.0034 -0.0819 28.1815
Karpas-299 GDSC1; GDSC2; CTRP2 1.2094 3.2077 1.1873 26.6742
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 1.2309 6.0978 0.5961 28.6189
RS4;11 GDSC1; GDSC2; CTRP2 1.2647 7.4733 0.1282 30.0216
MOLP-8 GDSC1; GDSC2; CTRP2 1.2656 7.2053 0.2334 29.6895
CTV-1 GDSC1; GDSC2 1.2792 2.6371 1.2355 20.722
Karpas-1106P GDSC1; GDSC2 1.3048 4.666 0.6492 23.7965
DND-41 GDSC1; GDSC2 1.3447 4.2911 0.8392 22.581
KMS-21-BM CTRP2 1.3485 4.0387 1.2482 26.0146
SU-DHL-6 GDSC1; GDSC2; CTRP2 1.3543 2.9068 1.3483 25.6565
TF-1 CTRP2 1.3599 2.7046 1.3576 25.607
SUP-B8 GDSC1; GDSC2 1.4317 3.5001 1.2078 20.1571
Mono-Mac-1 CTRP2 1.4371 7.5426 0.2836 28.9985
DEL GDSC1; GDSC2; CTRP2 1.4515 3.4484 1.4229 25.0859
HEL GDSC1; GDSC2; CTRP2 1.4647 5.1632 0.8972 21.5078
Farage GDSC1; GDSC2 1.4841 4.0556 1.0771 20.6502
NALM-6 GDSC1; GDSC2; CTRP2 1.5013 5.0665 1.2008 25.6945
SU-DHL-5 GDSC1; GDSC2; CTRP1 1.6279 3.8725 1.5683 30.4702
SUP-HD1 GDSC1; GDSC2; CTRP2 1.6435 6.092 1.0454 25.8017
SCC-3 GDSC1; GDSC2 1.6849 2.52 1.6748 16.4787
ARH-77 GDSC1; GDSC2 1.6873 5.0346 0.8934 20.8361
MHH-CALL-4 GDSC2; CTRP2 1.6984 5.8002 1.2015 25.0844
AMO1 GDSC1; GDSC2; CTRP2; CTRP1 1.7191 6.1881 1.0944 25.4006
SU-DHL-16 GDSC1; GDSC2 1.7669 3.2834 1.6352 16.297
HL-60 GDSC1; GDSC2; CTRP2 1.8215 7.2832 0.7941 26.1444
Ri-1 CTRP2 1.8267 5.3752 1.4712 23.7341
697 GDSC1; GDSC2; CTRP2 1.8745 5.6172 1.4509 23.6611
RCH-ACV GDSC1; GDSC2; CTRP2 1.8961 6.2379 1.2683 24.2512
NOMO-1 GDSC1; GDSC2; CTRP2; CTRP1 1.908 7.1333 0.9452 25.3642
L-540 GDSC1; GDSC2; CTRP2 1.9901 5.0705 1.733 22.3005
SIG-M5 GDSC1; GDSC2; CTRP2 2.0008 3.7519 1.9728 21.4314
BC-3 GDSC1; GDSC2 2.0109 5.6722 0.932 19.3382
H9 GDSC1; GDSC2 2.019 7.7201 -0.0391 24.4896
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 2.0959 5.4716 1.7365 21.9651
LAMA-84 GDSC1; GDSC2; CTRP2 2.11 6.286 1.1279 18.6465
JSC-1 GDSC1; GDSC2 2.1127 5.1595 1.27 16.9706
LP-1 GDSC1; GDSC2; CTRP2; CTRP1 2.1591 5.914 1.6646 22.0373
DoHH2 GDSC1; GDSC2 2.1736 3.4151 2.0421 12.2218
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 2.1786 6.7902 1.3672 23.0662
NCO2 CTRP2 2.1836 3.8435 2.0818 14.5657
BE-13 GDSC1; GDSC2 2.2017 4.1765 1.7934 13.5202
NKM-1 GDSC1; GDSC2 2.215 6.008 0.973 18.3354
BALL-1 GDSC1; GDSC2 2.2224 7.3426 0.3351 21.8558
EJM GDSC1; GDSC2; CTRP2; CTRP1 2.251 5.9154 1.7638 21.4033
WIL2 NS GDSC1; GDSC2 2.2619 4.7185 1.6204 14.3079
CRO-AP2 GDSC1; GDSC2 2.2791 4.1329 1.8926 12.6243
P32/ISH GDSC1; GDSC2 2.2792 3.4634 2.1424 11.1934
BL-70 CTRP2; CTRP1 2.2793 4.1284 2.2291 19.6549
KY821 GDSC1; GDSC2 2.2842 8.8689 -0.3577 25.0092
BL-41 GDSC1; GDSC2 2.2863 6.5028 0.8032 19.0552
TUR GDSC1; GDSC2 2.3012 4.2217 1.8784 12.618
Jiyoye GDSC1; GDSC2 2.3501 6.2989 0.9622 17.9078
Karpas-45 GDSC1; GDSC2 2.3526 6.8016 0.7204 19.2867
OCI-Ly19 GDSC1; GDSC2; CTRP2 2.3926 6.0599 1.8672 20.6084
MOLM-16 GDSC1; GDSC2; CTRP2; CTRP1 2.4034 5.8155 1.9625 20.2256
KMS-27 CTRP2 2.416 6.1129 1.8739 20.5158
RPMI-6666 GDSC1; GDSC2; CTRP2 2.4216 5.7559 2.0019 20.0276
CMK GDSC1; CTRP2 2.4289 4.7247 2.2922 18.9597
VAL GDSC1; GDSC2 2.4564 6.2283 1.0967 16.7394
P30/OHK GDSC1; GDSC2 2.4695 7.3173 0.5759 19.6814
MHH-PREB-1 GDSC1; GDSC2 2.4798 6.9202 0.7804 18.4987
HC-1 GDSC1; GDSC2 2.4978 6.7597 0.8758 17.8888
KMOE-2 GDSC1; GDSC2 2.5086 9.946 -0.6901 25.6685
Namalwa GDSC1; GDSC2; CTRP2 2.5537 8.388 1.0896 23.0258
JVM-3 GDSC1; GDSC2 2.5989 4.8132 1.9125 11.2743
YT GDSC1; GDSC2 2.6145 3.5341 2.4831 7.8101
MOLT-16 GDSC1; GDSC2; CTRP2 2.6713 6.5918 1.9691 19.4308
Ku812 GDSC1; GDSC2; CTRP2; CTRP1 2.6765 5.3191 2.4144 17.7626
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 2.6848 4.9271 2.5259 17.3375
EM-2 GDSC1; GDSC2; CTRP2 2.7266 5.1352 2.2561 12.17
U-698-M GDSC1; GDSC2 2.7414 3.8683 2.4862 7.264
CESS GDSC1; GDSC2 2.7449 5.641 1.6523 12.3669
HDLM-2 GDSC1; GDSC2; CTRP2 2.7864 8.0138 1.0008 17.3468
JJN-3 GDSC1; GDSC2; CTRP2 2.7911 6.9103 1.9688 19.0987
KG-1 GDSC1; GDSC2 2.8068 7.1456 0.9654 16.3238
WSU-NHL GDSC1; GDSC2 2.8098 6.9277 1.0762 15.6602
MOLT-4 GDSC1; GDSC2 2.8117 7.0632 1.0108 16.0413
MLMA GDSC1; GDSC2 2.8439 8.8169 0.1665 20.5933
BDCM CTRP2 2.8457 6.6649 2.1255 18.3517
Daudi GDSC1; GDSC2; CTRP2 2.8857 6.496 2.2347 17.8256
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 2.9125 6.6113 2.2176 17.8162
JURL-MK1 GDSC1; CTRP2 2.9382 5.6643 2.2502 11.5925
KOPN-8 GDSC1; GDSC2 2.9425 5.6577 1.8245 10.6401
Hs 445 GDSC1; GDSC2 2.9445 7.489 0.916 16.1665
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 2.9654 5.9245 2.5336 16.4724
JVM-2 GDSC1; GDSC2; CTRP2 2.9732 7.674 1.3424 15.4198
BV-173 GDSC1; GDSC2; CTRP2 2.9848 8.7291 1.3708 20.8469
MEG-01 GDSC1; GDSC2 2.9973 5.7328 1.8363 10.3895
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 2.9984 8.1221 1.6605 19.7181
PF-382 GDSC1; GDSC2; CTRP2 3.0001 5.4752 2.7208 15.6783
EB1 CTRP2 3.002 5.8187 2.6103 16.0803
MHH-CALL-2 GDSC1; GDSC2 3.0798 6.3623 1.5956 11.633
JeKo-1 GDSC1; GDSC2; CTRP2 3.1099 7.3027 2.1364 17.5927
Peer CTRP2 3.1523 4.3861 2.9937 7.876
Mino CTRP2 3.1594 4.9286 3.0421 14.0369
MOLT-3 CTRP2 3.1785 5.1136 3.0185 14.0618
P12-Ichikawa GDSC1; GDSC2; CTRP2 3.1792 4.9923 3.0491 13.9509
MOLT-13 GDSC1; GDSC2 3.1857 4.7283 2.5022 5.6003
RPMI-8866 GDSC1 3.1866 6.7019 0.8305 8.8786
VL51 GDSC1; GDSC2 3.2017 8.2347 0.7647 16.2337
LC4-1 GDSC1; GDSC2 3.2229 6.7556 1.5219 11.6534
RPMI-8402 GDSC1; GDSC2; CTRP2 3.2602 5.6427 2.5848 9.2809
SUP-T1 GDSC1; GDSC2; CTRP2 3.2652 6.3672 2.6885 15.0405
EHEB GDSC1; CTRP2 3.2655 7.827 0.3366 8.4529
IM-9 GDSC1; GDSC2 3.2947 4.2662 2.8269 3.2147
K-562 GDSC1; GDSC2; CTRP2 3.3072 5.0481 3.1752 13.1072
HEL 92.1.7 CTRP2 3.3241 5.4081 3.0944 13.3472
BC-1 GDSC1; GDSC2 3.3292 8.5329 0.7225 16.087
CML-T1 GDSC1; GDSC2; CTRP2 3.3327 6.2127 2.3881 9.9499
CTB-1 GDSC1; GDSC2 3.3623 8.8673 0.5828 16.766
GA-10 GDSC1; GDSC2; CTRP2 3.3708 7.6835 2.2349 16.5271
EB2 GDSC1; GDSC2 3.3763 7.0956 1.4802 11.4581
HPB-ALL CTRP2 3.4027 6.6713 2.7093 14.5853
L-428 GDSC1; GDSC2; CTRP2 3.4272 7.7234 2.2737 16.2299
SK-MM-2 GDSC1; GDSC2; CTRP2 3.4389 10.4971 0.9762 21.1541
QIMR-WIL GDSC1; GDSC2 3.4485 7.4508 1.362 11.9743
KE-97 CTRP2; CTRP1 3.4532 6.3943 2.8765 13.801
CA46 GDSC1; GDSC2; CTRP2 3.48 6.7298 2.7654 14.1596
CCRF-CEM GDSC1; GDSC2 3.4935 5.8478 2.199 6.6253
RC-K8 GDSC1; GDSC2 3.5055 6.0011 2.1321 7.0149
DG-75 GDSC1; GDSC2 3.6023 7.2329 1.5949 10.1128
SUP-B15 GDSC1; GDSC2; CTRP2 3.6036 5.7901 3.27 11.8804
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 3.6144 7.8787 2.3901 15.2968
MY-M12 GDSC1; GDSC2 3.6412 5.7867 2.3444 5.3206
Sc-1 GDSC1 3.6818 10.5823 -0.9831 16.3314
KE-37 GDSC1; GDSC2; CTRP2 3.6907 5.1098 3.5781 10.4903
HH [Human lymphoma] GDSC1; GDSC2 3.729 8.8242 0.9022 13.9131
MOLM-6 CTRP2 3.8056 6.7058 3.1126 11.9383
Loucy GDSC1; GDSC2 3.836 6.5995 2.0894 6.4277
ME1 GDSC1; GDSC2 3.8527 6.1045 2.3444 4.8058
MN-60 GDSC1; GDSC2 3.8666 7.5344 1.6506 9.0695
Jurkat GDSC1; GDSC2; CTRP2 3.9195 7.3242 2.3795 8.6021
U-937 CTRP2; CTRP1 3.9608 5.54 3.744 9.0784
KO52 CTRP2 3.9642 5.3378 3.8134 8.8122
Kasumi-2 CTRP2 3.9758 7.4598 2.9426 12.1871
U266B1 GDSC1; GDSC2; CTRP2 4.0201 9.4843 2.0148 15.8229
Hs 611.T CTRP2 4.0846 8.3407 2.63 13.1943
KCL-22 GDSC1; GDSC2; CTRP2 4.202 7.7579 2.4026 7.8977
KYO-1 CTRP2 4.2506 5.4009 4.1051 6.8937
Karpas-422 GDSC1; GDSC2; CTRP2 4.2878 6.5931 3.6532 8.5531
ROS-50 GDSC1; GDSC2 4.4445 8.6485 1.5263 8.4323
MOTN-1 CTRP2 4.468 5.6147 4.2623 5.6815
Granta-519 GDSC1; GDSC2; CTRP2 4.4821 7.0838 3.6137 8.2421
RL GDSC1; GDSC2; CTRP2 4.497 5.3339 4.3947 5.1009
ST486 GDSC1; GDSC2; CTRP2 4.518 6.0443 4.1335 6.0511
KM-H2 GDSC1; GDSC2; CTRP2 4.5219 10.4973 1.2945 12.151
SU-DHL-8 GDSC1; GDSC2; CTRP2 4.5493 6.1266 4.1285 5.9914
HT GDSC1; GDSC2; CTRP2; CTRP1 4.5562 5.1182 4.5192 4.4714
NU-DHL-1 CTRP2 4.5861 8.9067 2.8186 11.2918
HD-MY-Z CTRP2 4.6032 6.3343 4.0866 6.0258
MC116 GDSC1; GDSC2; CTRP2; CTRP1 4.6052 5.2989 4.5236 4.3073
SU-DHL-10 GDSC1; GDSC2; CTRP2 4.6131 5.8654 4.3098 5.1066
P31/FUJ GDSC1; GDSC2; CTRP2 4.6289 7.9432 2.6508 5.9531
DB GDSC1; GDSC2; CTRP2 4.7403 6.1965 4.2858 4.8853
KMM-1 CTRP2 4.7759 9.7276 1.8785 9.1151
Karpas-231 GDSC1; GDSC2 4.7803 7.2484 2.3996 2.7203
MHH-CALL-3 CTRP2 4.7855 10.6441 2.1312 13.682
REC-1 CTRP2 4.8086 6.5372 4.1877 5.1274
TK [Human B-cell lymphoma] GDSC1; GDSC2 4.8103 6.8132 2.6051 1.6326
OCI-Ly3 CTRP2 4.8535 5.5745 4.684 3.0026
SUP-T11 CTRP2 4.9227 5.8218 4.6407 3.0031
MOLP-2 CTRP2 4.9604 11.712 1.7484 14.843
P3HR-1 CTRP2; CTRP1 4.9913 7.9769 3.64 7.0173
ME1 CTRP2 5.0771 7.8585 3.7731 6.2862
Ci-1 CTRP2 5.101 5.6366 4.8999 1.5241
Ramos.2G6.4C10 GDSC1; GDSC2 5.264 11.7465 0.5977 11.8342
OCI-Ly10 CTRP2; CTRP1 5.4955 9.4299 3.3327 7.3379
Reh GDSC1; GDSC2; CTRP2 5.9603 15.5475 0.6521 16.9549
Raji GDSC1; GDSC2; CTRP2 7.1433 8.467 4.7798 0.1585
⏷ Show the Full List of 218 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 1.6839 4.9322 1.4339 24.3068
TE15 CTRP2 3.3962 5.61 3.1083 13.0836
TE-8 GDSC1; GDSC2 -0.0921 3.6052 -0.4849 36.005
TE-15 GDSC1 0.066 3.2739 -0.4425 30.4412
TE-11 GDSC1; GDSC2; CTRP2 1.1039 4.0523 0.9836 27.7081
T.T GDSC1; GDSC2 1.5455 4.3195 1.0423 20.5818
OE21 GDSC1; GDSC2; CTRP2 2.1106 5.9207 1.6097 22.3806
TE-1 GDSC1; GDSC2; CTRP2 2.1246 7.2871 1.113 24.1407
KYSE-270 GDSC1; GDSC2 2.3457 5.2429 1.4626 14.9417
TE-9 GDSC1; GDSC2; CTRP2 2.678 6.6179 1.5553 15.2737
KYSE-180 GDSC1; GDSC2; CTRP2 3.0252 6.5136 2.3759 16.9
KYSE-410 GDSC1; GDSC2; CTRP2; CTRP1 3.0514 6.3804 2.456 16.5217
KYSE-140 GDSC2; CTRP2; CTRP1 3.085 7.7657 1.9078 18.5428
KYSE-30 CTRP2 3.1149 9.0384 1.3568 20.564
KYSE-510 GDSC1; GDSC2; CTRP2 3.1874 5.2205 2.9998 14.1019
TE-6 GDSC1; GDSC2 3.2375 5.5831 2.1203 7.8562
TE-10 GDSC1; GDSC2; CTRP2 3.3576 7.789 1.6456 13.1577
COLO 680N GDSC1; GDSC2; CTRP2 3.3741 6.6005 2.7089 14.6639
KYSE-150 GDSC1; GDSC2; CTRP2 3.3918 5.0856 3.2582 12.5506
KYSE-70 GDSC1; GDSC2; CTRP2 3.4177 5.6979 3.1018 13.045
OE33 GDSC1; GDSC2; CTRP2 3.9162 6.5524 3.2933 10.9368
TE-5 GDSC1; GDSC2; CTRP2 4.3008 6.4014 3.7532 8.1206
KYSE-520 GDSC1; GDSC2; CTRP2 4.345 6.2442 3.8684 7.5491
TE-4 GDSC1; GDSC2; CTRP2 4.4711 7.6278 3.3408 9.3887
KYSE-450 GDSC1; GDSC2; CTRP2; CTRP1 4.5375 6.8936 3.758 7.5214
EC-GI-10 GDSC1; GDSC2; CTRP2 4.6565 6.8356 3.8995 6.6631
OE19 GDSC1; GDSC2; CTRP2 5.0164 8.1011 3.5998 7.1349
TE-14 CTRP2 5.7316 22.3454 -2.9274 27.1025
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 5.4767 18.0529 -0.991 22.9658
MZ-PC-1 GDSC1; GDSC2 0.2631 5.11 -0.631 34.6869
Capan-2 GDSC1; GDSC2; CTRP2; CTRP1 1.3437 4.9803 1.0509 26.7107
PaTu 8988s CTRP2 1.4289 9.0818 -0.3687 30.9833
HuP-T4 GDSC1; GDSC2; CTRP2; CTRP1 1.5954 4.9937 1.3221 24.9755
KP-2 GDSC1; GDSC2; CTRP2 1.6038 5.0275 1.3226 24.9476
TCC-Pan2 CTRP2 1.6355 5.0447 1.3528 24.7427
HPAC GDSC1; GDSC2; CTRP2; CTRP1 1.7752 4.8898 1.5437 23.6359
Panc 08.13 GDSC1; GDSC2; CTRP2 1.7976 6.6638 1.0078 25.4705
PL4 GDSC1; GDSC2 1.8044 4.8787 1.0818 19.2835
HuP-T3 GDSC1; GDSC2; CTRP2 2.1054 7.5972 0.9659 24.7191
YAPC GDSC1; GDSC2; CTRP2 2.1904 6.5683 1.4646 22.6766
BxPC-3 GDSC1; GDSC2; CTRP2 2.203 5.1108 1.9548 20.8557
Hs 766T GDSC1; GDSC2; CTRP2 2.3917 5.4482 2.066 19.8828
KP-3 GDSC1; GDSC2; CTRP2; CTRP1 2.5478 7.5444 1.4501 21.7207
PaTu 8988t GDSC1; GDSC2; CTRP2 2.6107 6.8281 1.8115 20.1939
KP-1N GDSC1; GDSC2 2.6255 6.0164 1.3579 14.5814
MIA PaCa-2 GDSC2; CTRP2 2.7031 6.5575 2.0163 19.1633
SNU-213 CTRP2 2.7979 7.5653 1.7006 20.0987
PaTu 8902 GDSC1; GDSC2; CTRP2; CTRP1 2.8226 7.2708 1.852 19.4571
PSN1 GDSC1; GDSC2; CTRP2 2.9122 5.5823 2.5915 16.4129
Panc 05.04 CTRP2 2.9457 7.2572 1.9858 18.6127
Panc 10.05 GDSC1; GDSC2; CTRP2; CTRP1 3.0218 7.6612 1.8894 18.78
DAN-G GDSC1; GDSC2; CTRP2 3.0348 9.5535 1.0369 21.9453
PK-59 CTRP2 3.1591 5.6313 2.8439 14.7556
Capan-1 GDSC1; GDSC2; CTRP2 3.1985 6.5313 2.5523 15.7465
HPAF-II GDSC1; GDSC2 3.3785 13.2968 -1.6184 26.4456
AsPC-1 GDSC1; GDSC2; CTRP2 3.4061 7.8055 2.2153 16.514
SU.86.86 GDSC1; GDSC2 3.5441 6.4418 1.9431 8.0993
CFPAC-1 GDSC1; GDSC2; CTRP2; CTRP1 3.7757 6.995 2.9543 12.6423
SUIT-2 GDSC1; GDSC2; CTRP2; CTRP1 3.9788 7.3191 3.0109 11.9049
QGP-1 GDSC1; GDSC2; CTRP2; CTRP1 3.9996 15.0913 -0.7727 25.4297
SW1990 GDSC1; GDSC2; CTRP2 4.0583 6.2034 3.5903 9.3958
Panc 04.03 GDSC1; GDSC2; CTRP2 4.2778 10.5589 1.7235 16.3896
Panc 03.27 GDSC1; GDSC2; CTRP2; CTRP1 4.3408 6.7896 3.6153 8.5745
KP-4 GDSC1; GDSC2; CTRP2 4.4054 6.9573 3.5999 8.4806
Panc 02.03 GDSC1; GDSC2; CTRP2 4.4525 7.2872 3.4878 8.8276
PK-45H CTRP2 4.812 6.6406 4.1406 5.3142
L3.3 CTRP2 5.1245 5.9 4.7911 1.926
SNU-410 CTRP2 6.4998 10.6719 3.4644 5.1749
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 2.8469 9.7264 0.7714 23.3749
CP67-MEL GDSC1 -0.0863 4.9775 -1.2997 36.6272
MMAc-SF GDSC1; GDSC2 0.0309 3.7743 -0.4026 35.0022
SH-4 GDSC1; GDSC2 0.6687 7.3043 -1.1576 34.5748
WM35 GDSC1; GDSC2 0.9882 5.8468 -0.1801 29.3539
VMRC-MELG GDSC1; GDSC2 1.1291 3.1082 0.9836 22.7633
CP50-MEL-B GDSC1; GDSC2 1.5276 5.0213 0.7342 22.385
LOX-IMVI GDSC1; GDSC2; CTRP2 1.7893 3.3832 1.7764 22.787
Hs 852.T CTRP2; CTRP1 1.8271 7.0798 0.8803 25.8293
A-375 GDSC1; GDSC2; CTRP2; CTRP1 1.8657 5.4581 1.4895 23.55
WM278 GDSC1; GDSC2 1.8673 5.948 0.6618 21.4211
M14 GDSC1; GDSC2 1.9136 7.3309 0.0497 24.454
CHL-1 GDSC1; GDSC2 2.0097 4.87 1.2962 17.2157
COLO 792 GDSC1; GDSC2; CTRP2 2.2179 6.2319 1.6178 22.0356
MZ-MEL-2 GDSC1; GDSC2 2.2738 7.6568 0.2291 22.2215
A-431 GDSC1; GDSC2 2.4218 4.2872 1.9749 11.5671
IST-MEL1 GDSC1; GDSC2 2.5038 4.4763 1.9741 11.2538
WM1552C GDSC1; GDSC2 2.6881 5.8722 1.4865 13.5819
HMV-II GDSC1; GDSC2 2.7024 8.8143 0.0438 21.6763
HT-144 GDSC1; GDSC2; CTRP2 2.7594 5.1878 2.5416 17.0524
RPMI-7951 GDSC1; GDSC2; CTRP2 2.7793 4.8007 2.6568 16.5811
SK-MEL-24 GDSC1; GDSC2; CTRP2 2.7903 6.6117 2.0878 18.6491
G-mel GDSC1; GDSC2 2.9157 4.8839 2.181 8.4982
A-388 GDSC1; GDSC2 2.9175 4.6774 2.2834 7.854
Malme-3M CTRP2 2.9639 9.1252 1.1671 21.6545
COLO 783 GDSC1; GDSC2 2.9714 5.1253 2.1137 8.7334
MDA-MB-435S CTRP2 3.1953 7.002 2.3538 16.5222
Hs 938.T GDSC1; GDSC2 3.2167 6.7495 1.5197 11.6852
Hs 688(A).T CTRP2 3.2632 9.3588 1.3519 20.207
Hs 895.T CTRP2 3.3348 6.4045 2.7473 14.6227
WM88 CTRP2 3.3401 5.568 3.0613 13.4218
IGR-1 GDSC1; GDSC2; CTRP2 3.3991 6.3148 2.8512 14.0467
WT2-iPS GDSC1; GDSC2; CTRP2 3.5004 6.0608 3.0583 12.9736
WM115 GDSC1; GDSC2; CTRP2 3.6336 5.1525 3.5049 10.9273
IGR-39 CTRP2 3.6436 5.5965 3.3812 11.3494
HMCB CTRP2 3.673 5.8929 3.3066 11.5454
WM266-4 CTRP2 3.9364 7.4191 2.9225 12.3653
MeWo GDSC1; GDSC2; CTRP2 4.0524 7.1518 3.1614 11.1166
COLO 829 GDSC1; GDSC2; CTRP2 4.0665 7.2049 3.1509 11.1242
Hs 940.T GDSC1; GDSC2; CTRP2 4.1409 8.398 2.6559 12.9576
CJM [Human melanoma] CTRP2 4.1787 5.6859 3.9262 7.7707
WM1799 CTRP2 4.258 7.3642 3.2639 10.2016
COLO 679 GDSC1; GDSC2 4.2872 8.5874 1.4439 9.2876
Hs 944.T CTRP2; CTRP1 4.3672 5.9146 4.0341 6.8382
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 4.3802 8.2448 2.9553 11.1831
Hs 294T CTRP2 4.4374 6.0342 4.0555 6.5691
SK-MEL-3 GDSC1; GDSC2; CTRP2 4.4531 9.5121 2.3993 13.3026
A101D GDSC1; GDSC2; CTRP2 4.5144 9.9805 2.2225 13.8872
LB2518-MEL GDSC1; GDSC2 4.5168 10.1053 0.8672 12.0785
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 4.5218 5.7936 4.2463 5.597
IPC-298 GDSC1; GDSC2; CTRP2 4.5565 7.5839 3.4421 8.7769
451Lu GDSC1; GDSC2 4.5855 6.5688 2.5913 1.9967
Mel Ho GDSC1; GDSC2; CTRP2 4.6393 7.1631 3.7246 7.423
GAK GDSC1; GDSC2 4.6921 6.8417 2.5301 2.163
COLO 741 CTRP2; CTRP1 4.7741 16.2976 -0.7014 23.5611
MZ-MEL-7 GDSC1; GDSC2 4.7784 9.5648 1.3151 8.9286
G-361 GDSC1; GDSC2; CTRP2; CTRP1 4.7958 5.7238 4.5592 3.6463
A2058 GDSC1; GDSC2; CTRP2 4.8526 5.3872 4.7602 2.7093
UACC-257 GDSC1; GDSC2; CTRP2 4.9117 10.9463 2.0893 13.5912
SK-MEL-2 GDSC1; GDSC2; CTRP2 5.0052 5.8218 4.72 2.4843
Hs 839.T CTRP2 5.0121 6.6917 4.2981 4.2217
DJM-1 GDSC1; GDSC2 5.02 12.8086 -0.0914 15.8463
WM793 GDSC1; GDSC2; CTRP2 5.0253 5.7752 4.7615 2.2671
Hs 936.T CTRP2; CTRP1 5.0894 9.6525 2.8871 9.9673
WM983B CTRP2 5.1272 9.1421 3.1741 8.696
Mel JuSo GDSC1; GDSC2; CTRP2 5.2457 11.9898 1.8494 13.8781
RVH-421 GDSC1; GDSC2; CTRP2 5.3508 7.7797 4.0401 4.6405
IGR-37 GDSC1; GDSC2; CTRP2 5.3565 8.4426 3.7138 5.9977
LB373-MEL-D GDSC1; GDSC2 5.3753 14.6717 -0.746 17.9553
COLO 800 GDSC1; GDSC2; CTRP2 5.4052 9.3587 3.2956 7.6582
UACC-62 GDSC1; GDSC2; CTRP2 5.445 10.1058 2.9547 9.0055
CP66-MEL GDSC1; GDSC2 5.4492 13.4062 -0.0762 14.7948
SK-MEL-31 GDSC1; GDSC2; CTRP2 5.7743 10.1322 3.2015 7.3922
K029AX CTRP2 6.2189 9.9324 3.6272 4.9269
SK-MEL-30 GDSC1; GDSC2; CTRP2 7.3016 12.0119 3.3534 4.5541
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 7.4634 14.4907 2.2863 8.4462
EquiPSC Line K2 GDSC1; GDSC2 4.0328 9.0635 1.0199 12.4188
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC1; GDSC2 -0.5742 2.5826 -0.7534 39.8158
TE-12 GDSC1; GDSC2 0.0645 5.881 -1.1535 37.4684
OACM5.1 C GDSC1; GDSC2 0.935 3.878 0.5464 25.9972
KYSE-220 GDSC1; GDSC2 1.4849 5.3353 0.5539 23.55
KYSE-50 GDSC1; GDSC2 1.7497 4.3207 1.2584 18.4906
FLO-1 GDSC1; GDSC2 2.3452 6.047 1.0791 17.2391
HCE-4 GDSC1; GDSC2 2.6813 5.2285 1.7934 11.7129
SK-GT-4 GDSC1; GDSC2 3.082 6.3847 1.5862 11.6844
ESO-26 GDSC1; GDSC2 3.3581 4.8127 2.6065 4.4256
KYAE-1 GDSC1; GDSC2 3.4206 5.1905 2.4685 5.1233
ESO-51 GDSC1; GDSC2 4.2629 6.4133 2.4724 3.1795
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 5.0137 6.3624 4.4627 3.5318
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC1; GDSC2 -1.6797 2.6065 -1.9591 50.1639
LA-N-6 GDSC1; GDSC2 -0.8985 4.1257 -1.5261 43.9275
NB(TU)1 GDSC1; GDSC2 -0.7703 2.4669 -0.9431 41.6863
CHP-212 GDSC1; GDSC2; CTRP2 0.2424 3.9349 0.076 33.5697
TGW GDSC1; GDSC2 0.3256 4.9615 -0.5064 33.8873
SJNB-12 GDSC1; GDSC2 0.5679 3.9381 0.1281 29.8619
KP-N-RT-BM-1 GDSC1; GDSC2 0.7621 4.974 -0.0483 29.7809
SK-N-FI GDSC1; GDSC2; CTRP2 0.7978 5.3266 0.3624 30.7824
NB1 GDSC1; GDSC2; CTRP2 1.2935 3.2153 1.2738 26.1068
MHH-NB-11 GDSC1; GDSC2; CTRP2 1.4064 5.7419 0.6157 22.7999
SK-N-SH GDSC1; GDSC2; CTRP2 1.417 5.6598 0.9395 26.8673
SK-N-MC-IXC GDSC1; GDSC2 1.4593 5.0541 0.6494 23.1376
SiMa GDSC1; GDSC2; CTRP2 1.4779 6.0177 0.8909 26.8468
SJNB-10 GDSC1; GDSC2 1.4814 5.9935 0.256 25.1319
KP-N-SI9s CTRP2 1.5442 5.8832 1.0071 26.239
GI-ME-N GDSC1; GDSC2 1.6961 9.2045 -1.0641 30.0234
SK-N-DZ GDSC1; GDSC2; CTRP2 1.735 6.0205 1.1688 25.0894
NH-12 GDSC1; GDSC2 1.8234 5.7704 0.7005 21.3779
SK-N-BE(2)-M17 GDSC1; GDSC2 1.8927 6.3431 0.5013 22.2017
SJNB-5 GDSC1; GDSC2 2.2878 6.7737 0.6732 19.784
SJNB-13 GDSC1; GDSC2 2.3266 7.9951 0.1116 22.6297
KP-N-YS GDSC1; GDSC2 3.19 9.5695 0.0875 19.896
NH-6 CTRP2 3.2024 8.5487 1.6708 19.1518
SK-N-AS GDSC1; GDSC2; CTRP2 3.3999 7.0447 2.5474 15.2245
SJNB-14 GDSC1; GDSC2 3.4946 6.9392 1.6551 10.0375
GOTO GDSC1; GDSC2 3.5245 9.4915 0.4043 17.2549
SK-N-BE(2) CTRP2 3.8776 13.9567 -0.3183 24.3929
IMR-5 GDSC1; GDSC2 4.1477 10.1702 0.5593 14.7018
IMR-32 CTRP2 4.2651 5.3759 4.1291 6.7625
SJNB-7 GDSC1; GDSC2 4.3659 9.8048 0.9041 12.2387
Kelly GDSC1; GDSC2; CTRP2 4.6599 12.765 0.9644 18.4202
CHP-126 GDSC1; GDSC2; CTRP2 4.6647 7.4305 3.6177 7.8076
KP-N-YN GDSC1; GDSC2; CTRP2 4.7813 6.8851 3.9927 5.9945
CHP-134 GDSC2 4.8356 6.764 2.6387 1.4443
SJNB-17 GDSC1; GDSC2 5.1239 11.6527 0.5459 12.4142
SJNB-6 GDSC1; GDSC2 5.1388 6.5923 2.8425 0.4128
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 0.0963 3.2892 0.0126 34.2742
HuH-28 CTRP2 1.2939 3.4809 1.2557 26.1665
SNU-1196 CTRP2 1.5391 5.9127 0.9919 26.3082
SNU-478 CTRP2 2.2495 5.0135 1.7956 15.4853
HuCC-T1 GDSC1; GDSC2; CTRP2 3.4522 6.3185 2.906 13.6899
SNU-245 CTRP2 3.7552 8.256 2.3525 15.1002
SNU-308 CTRP2 4.6207 9.5662 1.8376 9.5895
SNU-869 CTRP2 5.6421 8.0139 4.1494 3.6805
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MCF-7 GDSC1; GDSC2; CTRP1 0.7143 4.7439 0.4226 38.9274
HMC-1-8 CTRP2 1.6874 4.9144 1.4421 24.2672
DU4475 GDSC1; GDSC2; CTRP2 2.0879 3.9068 2.0506 20.8836
CAL-51 GDSC1; GDSC2; CTRP2 2.2599 4.562 2.1413 20.0199
HCC1395 GDSC1; GDSC2; CTRP2 2.3003 4.6462 1.9821 14.5769
HCC1806 GDSC1; GDSC2 2.396 6.6379 0.8407 18.4481
HCC1143 GDSC1; GDSC2; CTRP2 2.4067 6.9449 1.5488 21.7479
Hs 578T GDSC1; GDSC2 2.4661 3.7991 2.225 9.9175
HCC1569 GDSC1; GDSC2 2.5283 4.5187 1.9795 11.128
HCC2157 GDSC1; GDSC2 2.6798 9.0297 -0.0832 22.3726
Evsa-T GDSC1; GDSC2 2.7439 4.4747 2.2137 8.9004
CAL-120 GDSC1; GDSC2; CTRP2 2.9427 6.5349 2.2799 17.495
CAL-85-1 GDSC1; GDSC2; CTRP2 3.0328 7.4006 2.0145 18.2689
HDQ-P1 GDSC1; GDSC2; CTRP2 3.0658 6.6838 2.3504 16.8858
JIMT-1 GDSC1; GDSC2; CTRP2 3.1041 5.1648 2.9239 14.6285
MFM-223 GDSC1; GDSC2 3.1723 5.7722 1.97 9.0021
HCC1187 GDSC1; GDSC2 3.1989 6.9406 1.4091 12.4209
MDA-MB-468 GDSC1; GDSC2; CTRP2 3.2703 5.1492 3.1093 13.4555
ZR-75-1 CTRP2 3.2743 7.5159 2.2118 16.8669
COLO 824 GDSC1; GDSC2 3.421 7.8961 1.1169 13.5303
HCC1599 GDSC1; GDSC2 3.8209 11.1055 -0.1622 19.2639
MDA-MB-231 GDSC1; GDSC2; CTRP2 3.866 6.4738 3.2753 11.1398
HCC38 GDSC1; GDSC2; CTRP2 3.9194 6.8235 3.1771 11.3889
HCC2218 GDSC1; GDSC2 3.9278 9.2727 0.8352 13.7549
MDA-MB-175-VII GDSC1; GDSC2 4.0002 6.5414 2.2365 5.1321
KPL-1 CTRP2 4.075 7.1842 3.1689 11.0306
HCC1954 GDSC1; GDSC2 4.0899 6.1231 2.498 3.3605
BT-20 GDSC1; GDSC2; CTRP2 4.1265 5.7708 3.8379 8.2532
MDA-MB-453 GDSC1; GDSC2; CTRP2 4.155 6.349 3.6278 8.9938
MRK-nu-1 GDSC1; GDSC2 4.1787 6.4467 2.4029 3.7483
AU565 GDSC1; GDSC2; CTRP2 4.2282 6.6163 3.5828 8.9851
EFM-19 GDSC1; GDSC2 4.2545 10.9182 0.2702 15.9487
HCC1500 GDSC1; GDSC2; CTRP2 4.3252 7.373 3.3246 9.7942
OCUB-M GDSC1; GDSC2 4.3787 7.5989 1.9871 5.8196
MDA-MB-436 GDSC1; GDSC2 4.4159 7.5642 2.0286 5.4945
T-47D GDSC1; GDSC2; CTRP2 4.4269 11.3255 1.4771 17.014
UACC-893 GDSC1; GDSC2 4.4947 6.7605 2.4538 2.8781
EFM-192A GDSC1; GDSC2 4.527 5.9443 2.8268 0.9294
CAL-148 GDSC1; GDSC2; CTRP2 4.6582 8.2764 2.5081 6.5369
HCC1937 GDSC1; GDSC2; CTRP2 4.6944 8.9284 2.2124 7.7881
BT-549 GDSC1; GDSC2; CTRP2 4.7089 5.4578 4.5799 3.798
Hs 578Bst CTRP2 4.7322 7.2971 3.7454 7.1287
MDA-MB-415 GDSC1; GDSC2; CTRP2 4.7739 7.1629 3.8496 6.6042
BT-483 GDSC1; GDSC2 4.9204 10.977 0.7308 11.8864
HCC70 GDSC1; GDSC2 4.9857 9.5683 1.4527 7.7025
UACC-812 GDSC2 5.1698 7.0747 2.671 0.9756
SK-BR-3 CTRP2 5.1822 6.2124 4.6851 2.2533
HCC1428 GDSC1; GDSC2; CTRP2 5.2284 6.1823 4.7387 1.939
CAMA-1 GDSC1; GDSC2; CTRP2 5.2781 7.5644 2.5242 1.1238
MDA-MB-361 GDSC1; GDSC2; CTRP2 5.314 12.7388 1.5315 14.978
HCC202 GDSC1; CTRP2 5.4827 7.2305 4.4167 2.8355
BT-474 GDSC1; GDSC2; CTRP2 5.5063 8.2456 3.9311 4.8183
MDA-MB-330 GDSC1; GDSC2 5.6308 10.612 1.3742 6.9134
MDA-MB-157 GDSC1; GDSC2; CTRP2 5.6492 13.5145 1.4175 14.7694
ZR-75-30 GDSC1; GDSC2; CTRP2 6.3296 8.5793 4.3412 1.9666
YMB-1-E GDSC2 6.6033 8.6184 2.6735 0.2536
HCC1419 GDSC1; GDSC2; CTRP2 7.1613 8.4949 4.7767 0.1588
BT 482 CTRP2 0.8192 4.4702 0.5979 29.9371
BT 416 CTRP2 0.9915 2.6254 0.9864 28.0659
BT 271 CTRP2 1.0185 9.8392 -1.1214 34.1885
BT 239 CTRP2 1.1039 7.9796 -0.2443 31.6404
BT 440 CTRP2 1.1216 4.587 0.9015 27.9312
BT 286 CTRP2 1.1753 6.4785 0.405 29.4243
BT 228 CTRP2 2.1074 5.0944 1.8548 21.5058
BT 328 CTRP2 2.2965 5.9321 1.8075 21.1094
BT 245 CTRP2 2.5784 14.1771 -1.6196 30.9625
BT 131 CTRP2 2.7021 9.2906 0.8305 23.5493
BT 159 CTRP2 3.0487 4.8963 2.9289 14.7816
BT 231 CTRP2 3.2843 8.9005 1.5881 19.2604
BT147 CTRP2 3.6009 11.201 0.7864 21.4395
BT 340 CTRP2 3.6435 10.4981 1.1686 19.9588
BT 139 CTRP2 4.1031 5.2597 3.988 7.7606
BT 330 CTRP2 4.2969 14.6929 -0.3127 23.4386
BT 179 CTRP2 4.3945 5.7282 4.1394 6.3563
BT 187 CTRP2 4.4193 9.4099 2.4191 13.2958
BT 172 CTRP2 4.5413 12.0479 1.2186 17.7414
BT164 CTRP2 4.6073 5.654 4.3939 4.7924
BT 145 CTRP2 4.6561 5.8765 4.349 4.8403
BT 359 CTRP2 4.7008 12.2823 1.2407 17.32
BT 248 CTRP2 4.7718 5.799 4.5011 3.9392
BT 232 CTRP2 4.7895 12.1099 1.4033 16.5235
BT 224 CTRP2 4.8153 6.3064 4.3058 4.626
BT 112 CTRP2 5.0008 6.033 4.6131 2.9354
BT 216 CTRP2 5.0023 9.0083 3.1347 9.109
BT 504 CTRP2 5.0255 16.4496 -0.5647 22.6516
BT 428 CTRP2 5.1244 6.0593 4.7118 2.2579
BT 444 CTRP2 5.2735 6.0879 4.8224 1.5047
BT 422 CTRP2 5.3198 8.3748 3.7178 6.049
BT 333 CTRP2 5.6717 14.8761 0.7558 17.1342
BT 320 CTRP2 5.6897 13.1024 1.6557 13.786
BT 498 CTRP2 6.0369 7.4973 4.6594 1.1184
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.7619 6.2131 2.7911 7.1139
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 0.4164 4.8797 -0.3779 32.9083
D-336MG GDSC1; GDSC2 0.4681 4.3883 -0.1373 31.6033
PFSK-1 GDSC1; GDSC2 0.496 7.4004 -1.3748 36.0279
D-245MG GDSC2 2.0994 5.3373 1.1751 17.5821
42-MG-BA GDSC1; GDSC2; CTRP2 2.2359 4.4381 2.1377 20.1082
D-423MG GDSC1; GDSC2 2.3049 4.4025 1.8044 13.0418
8-MG-BA GDSC1; GDSC2; CTRP2 2.3297 5.0041 2.1203 19.8759
D-263MG GDSC1; GDSC2 2.4021 5.5107 1.3907 15.17
D-566MG GDSC1; GDSC2 2.4469 3.6001 2.2788 9.6921
MOG-G-CCM GDSC1; GDSC2 2.5294 4.2704 2.0925 10.4438
SW1088 GDSC1; GDSC2; CTRP2 2.559 5.0873 2.3493 18.3543
SF539 GDSC1; GDSC2; CTRP2 2.599 3.7282 2.5926 17.3806
CAS-1 GDSC1; GDSC2 2.6246 3.9855 2.3149 8.7437
H4 GDSC1; GDSC2 2.7187 5.7206 1.589 12.847
GB-1 GDSC1; GDSC2; CTRP2 2.7219 8.6906 1.1245 22.4461
D-247MG GDSC1; GDSC2 2.7532 4.5567 2.1841 9.0479
DBTRG-05MG GDSC1; GDSC2; CTRP2 2.7594 6.0569 2.2642 18.0721
SNB-75 GDSC1; GDSC2; CTRP2 2.8111 6.5729 2.1251 18.4497
D-392MG GDSC1; GDSC2 2.816 5.5392 1.7678 11.4109
M059J GDSC1; GDSC2 2.8393 4.2421 2.4165 7.3097
KG-1-C CTRP2 2.8933 6.0627 2.4064 17.1555
GI-1 GDSC1; GDSC2 2.9142 7.18 1.0434 15.5157
SK-MG-1 GDSC1; GDSC2 2.9253 4.2808 2.482 6.5957
SF126 GDSC1; GDSC2; CTRP2 2.9841 5.1549 2.7956 15.455
Hs 683 GDSC1; GDSC2; CTRP2 3.0079 4.2705 2.9835 14.7222
SNU-738 CTRP2 3.0714 4.6944 2.9939 14.4821
T98G GDSC1; GDSC2; CTRP2 3.0742 6.1424 2.5714 16.0199
D283 Med GDSC1; GDSC2; CTRP2 3.1108 7.7937 1.9217 18.4215
MOG-G-UVW GDSC1; GDSC2 3.1464 5.2287 2.2186 7.5134
D-502MG GDSC1; GDSC2 3.1791 8.5277 0.5991 17.2309
LNZTA3WT4 GDSC1 3.1842 5.3554 1.1763 3.2552
D-542MG GDSC1; GDSC2 3.1892 4.469 2.6344 4.755
GaMG GDSC1; GDSC2; CTRP2; CTRP1 3.2103 5.4458 2.9588 14.1821
AM-38 GDSC1; GDSC2 3.2766 5.0546 2.4176 5.8587
KNS-60 CTRP2 3.3034 4.8316 3.2189 12.9646
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 3.4294 5.7862 3.0836 13.0792
SF268 GDSC1; GDSC2; CTRP2 3.4455 6.7615 2.7161 14.4441
ONS-76 GDSC1; GDSC2; CTRP2 3.4583 6.4062 2.4147 9.518
U-87MG ATCC GDSC1; GDSC2; CTRP2 3.6615 6.4046 2.0536 5.377
GMS-10 CTRP2 3.6757 6.0143 3.2632 11.7031
SNU-201 CTRP2 3.7274 5.0562 3.6311 10.1885
Becker GDSC1; GDSC2; CTRP2 3.769 7.3951 2.7667 13.4072
Onda 10 GDSC1; GDSC2 3.8444 6.2668 2.259 5.3541
SNU-626 CTRP2 3.8595 6.4919 3.2609 11.2133
U-118MG GDSC1; GDSC2; CTRP2 3.8658 6.4299 3.2939 11.0675
LN-405 GDSC1; GDSC2 3.9405 6.5006 2.214 5.4066
A-172 GDSC1; GDSC2; CTRP2 3.9803 6.283 3.4754 10.053
KINGS-1 GDSC1; GDSC2 4.0358 8.2862 1.4067 10.1252
SNU-489 CTRP2 4.0715 5.2059 3.9686 7.9265
SNU-1105 CTRP2 4.1694 8.277 2.7414 13.4923
U-251MG GDSC1; GDSC2; CTRP2 4.2097 6.107 3.7887 8.2171
LN-18 GDSC1; GDSC2; CTRP2 4.2285 7.1059 2.7504 6.2778
M059K CTRP2 4.4119 5.0941 4.3677 5.4558
Onda 11 GDSC1; GDSC2 4.4363 7.5203 2.063 5.2482
Daoy GDSC1; GDSC2; CTRP2 4.5252 5.7796 4.2557 5.5509
YH-13 GDSC1; GDSC2; CTRP2 4.5567 6.0237 4.1822 5.7583
SNU-466 CTRP2 4.6321 5.8432 3.68 1.4149
SF295 GDSC1; GDSC2; CTRP2; CTRP1 4.6567 6.4403 4.0891 5.8867
GOS-3 CTRP2 4.661 5.923 4.3331 4.8908
KALS-1 GDSC1; GDSC2; CTRP2 4.6833 6.4576 4.1067 5.7514
CCF-STTG1 CTRP2 4.6845 5.4436 4.5591 3.9456
DK-MG GDSC1; GDSC2; CTRP2 4.7216 5.6069 4.5333 3.9429
YKG-1 GDSC1; GDSC2; CTRP2 4.8005 7.8167 3.5511 7.7877
TM-31 CTRP2 4.9271 9.4733 2.8379 10.4969
SW1783 GDSC1; GDSC2; CTRP2 5.1896 6.7576 4.4188 3.3557
NMC-G1 GDSC1; GDSC2; CTRP2 5.2644 8.1561 3.7816 5.8855
KNS-42 GDSC1; GDSC2; CTRP2 5.4828 10.7945 2.6414 10.2311
KNS-81 CTRP2 5.5364 7.1899 4.4767 2.4989
KNS-81-FD GDSC1; GDSC2 5.5822 8.8796 2.1239 3.0118
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 -1.406 1.4573 -1.4734 47.555
ETK-1 GDSC1; GDSC2 1.0568 5.7005 -0.0457 28.4285
TGBC1TKB GDSC1; GDSC2 2.0635 6.9833 0.3599 22.3094
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 1.3149 4.2987 1.1687 26.3952
AN3-CA GDSC1; GDSC2; CTRP2 2.755 6.4834 2.1003 18.7007
HEC-151 CTRP2; CTRP1 2.83 5.5392 2.5156 16.9347
RL95-2 GDSC1; GDSC2; CTRP2 3.2294 7.4297 1.7024 13.22
MFE-280 GDSC1; GDSC2 3.4114 7.5347 1.2896 12.521
JHUEM-7 CTRP2 3.4351 6.1578 2.9512 13.5643
JHUEM-1 CTRP2 3.4588 7.9977 2.1802 16.5186
HEC-1-A CTRP2 3.4938 7.1361 2.604 14.7563
HEC-1-B CTRP2 3.7768 7.2939 2.2693 9.4142
MFE-296 GDSC1; GDSC2; CTRP2 3.8669 7.3238 2.8974 12.6388
JHUEM-3 CTRP2 3.9281 5.8068 3.6123 9.6673
KLE GDSC1; GDSC2; CTRP2; CTRP1 3.9309 8.058 2.6173 13.6103
ESS-1 GDSC1; GDSC2; CTRP2 3.9482 5.9075 3.595 9.6771
EFE-184 CTRP2 4.2198 7.6237 3.1033 10.947
HEC-6 CTRP2; CTRP1 4.2542 5.7435 3.9845 7.3377
HEC-265 CTRP2; CTRP1 4.3756 5.6389 4.1545 6.3507
MFE-319 GDSC1; GDSC2; CTRP2; CTRP1 4.4338 7.2012 3.5112 8.7752
EN GDSC1; GDSC2; CTRP2 4.4836 5.6626 4.2599 5.6475
HEC-50B CTRP2 4.7996 6.5933 4.152 5.295
HEC-108 CTRP2; CTRP1 5.0477 6.4913 4.4292 3.5992
HEC-59 CTRP2; CTRP1 5.5056 8.5971 3.7557 5.5523
HEC-251 CTRP2; CTRP1 5.5741 7.7808 4.2136 3.5262
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 4.7995 7.5356 3.6893 7.2143
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR10TKB CTRP2 -1.3466 5.0899 -1.9131 44.5236
LB996-RCC GDSC1; GDSC2 0.4159 2.8518 0.2654 29.9237
LB1047-RCC GDSC1; GDSC2 0.4247 3.1599 0.2028 30.194
TUHR14TKB CTRP2 0.5948 2.8939 -3.5813 0.5526
A-704 GDSC1; GDSC2 0.644 2.8365 0.5163 27.5277
RXF 393L GDSC1; GDSC2 1.4562 3.7291 1.1617 20.3012
A-498 GDSC1; GDSC2 1.5075 3.4213 1.3138 19.233
NCC021 GDSC1; GDSC2 1.7769 4.1102 1.3701 17.7362
CAL-54 GDSC1; GDSC2; CTRP2 1.9414 3.9165 1.8952 21.8878
KTCTL-13 GDSC1; GDSC2 1.9438 7.7254 -0.1124 25.1217
NCC010 GDSC1; GDSC2 2.0853 4.1275 1.6908 14.5967
KTCTL-26A GDSC1; GDSC2 2.1158 4.1122 1.7292 14.2474
UO-31 GDSC1; GDSC2; CTRP2 2.1739 3.8527 2.1456 20.2811
HA7-RCC GDSC1; GDSC2 2.2872 5.9079 1.0903 17.3833
KTCTL-140 GDSC1; GDSC2 2.3061 5.5347 1.2862 16.1485
KTCTL-1M GDSC1; GDSC2 2.3301 4.6444 1.7228 13.4313
BB65-RCC GDSC1; GDSC2 2.4914 4.8222 1.8026 12.3399
LB2241-RCC GDSC1; GDSC2 2.7544 6.9769 1.0024 16.2795
TK-10 GDSC1; GDSC2 2.7569 7.0691 0.9588 16.5269
SW13 GDSC1; GDSC2 2.7631 7.0378 0.9799 16.3829
KMRC-3 CTRP2 2.9291 5.7998 2.5378 16.5616
KMRC-1 GDSC1; GDSC2; CTRP2 3.0243 4.8756 2.9069 14.9353
VMRC-RCW GDSC2; CTRP2; CTRP1 3.0563 6.3598 2.4693 16.4575
KTCTL-195 GDSC1; GDSC2 3.0712 4.5832 2.4718 6.1585
786-O GDSC1; GDSC2; CTRP2 3.1594 5.1623 2.9849 14.2407
SW156 GDSC1; GDSC2 3.1682 4.4825 2.609 4.9818
769-P GDSC1; GDSC2 3.222 4.7499 2.5231 5.3559
BFTC-909 GDSC1; GDSC2; CTRP2 3.3185 6.4395 2.716 14.7878
SN12C GDSC1; GDSC2 3.3917 7.8935 1.094 13.7513
KMRC-2 CTRP2 3.4019 5.0667 3.2739 12.4634
KMRC-20 GDSC1; GDSC2; CTRP2 3.4908 6.4814 2.8805 13.6832
KTCTL-21 GDSC1; GDSC2 3.6127 6.0251 2.2043 6.2738
Caki-2 CTRP2 3.6633 5.9642 3.2692 11.7147
Caki-1 GDSC1; GDSC2; CTRP2 3.8273 7.1298 2.946 12.544
OS-RC-2 GDSC1; GDSC2; CTRP2 4.0951 8.9638 1.7103 11.2123
VMRC-RCZ GDSC1; GDSC2; CTRP2 4.1231 5.8378 3.8082 8.3761
TUHR4TKB CTRP2 4.4069 6.0184 4.0309 6.7456
ACHN GDSC1; GDSC2; CTRP2 4.4074 8.8362 2.6909 12.2095
SNU-1272 CTRP2 4.6383 11.7135 0.781 14.0765
RCC10RGB GDSC1; GDSC2; CTRP2; CTRP1 5.7455 13.3009 1.6013 13.8915
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 63 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KM12 GDSC1; GDSC2; CTRP2; CTRP1 -3.1901 1.2371 -3.2515 55.5741
SW48 GDSC1; GDSC2; CTRP2; CTRP1 -1.2681 2.5938 -1.3542 43.2758
COLO 320HSR GDSC1; GDSC2 -0.6761 5.0687 -1.6175 42.7173
COLO205 GDSC1; GDSC2; CTRP2; CTRP1 -0.578 2.5423 -0.6255 38.6315
SK-CO-1 GDSC1; GDSC2; CTRP2; CTRP1 -0.0088 4.3232 -0.2701 35.5089
NCI-H716 GDSC1; GDSC2; CTRP2 0.0583 2.5594 0.0339 34.3353
CL-34 CTRP1 0.3525 8.0808 -1.08 58.8344
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 0.9279 5.147 0.5538 29.7296
SNU-C1 GDSC1; GDSC2; CTRP2 0.9774 5.4594 0.5203 29.6799
NCI-H747 GDSC1; GDSC2 1.0066 5.9792 -0.2195 29.4494
LS513 GDSC1; CTRP2; CTRP1 1.2085 4.5747 0.9986 27.3205
LS411N GDSC1; GDSC2; CTRP2; CTRP1 1.2452 5.706 0.738 28.0958
COLO 320 CTRP2; CTRP1 1.3356 8.1885 -0.0863 30.4524
CaR-1 GDSC1; GDSC2 1.3836 3.9151 1.0193 21.4122
HCC2998 GDSC1; GDSC2 1.5704 3.6272 1.3191 18.9207
SNU-1040 GDSC1; CTRP1 1.6619 3.9938 1.5895 31.9694
GP2d CTRP2; CTRP1 1.8169 5.4883 1.4273 23.9208
SW948 GDSC1; GDSC2; CTRP2; CTRP1 1.9841 5.7392 1.5318 23.0399
SNU-1033 CTRP2 2.0874 6.3072 1.45 23.0299
SNU-175 GDSC2; CTRP2; CTRP1 2.3583 7.6605 1.2036 23.1517
CCK-81 GDSC1; GDSC2; CTRP2 2.3596 5.2125 2.0985 19.8622
SNU-407 GDSC1; GDSC2; CTRP2 2.3788 6.1959 1.8041 20.8816
T84 GDSC1; GDSC2; CTRP2 2.5188 6.5468 1.8238 20.4067
GP5d GDSC1; GDSC2 2.5778 6.3351 1.1577 15.9534
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 2.6138 6.8128 1.8209 20.1499
C2BBe1 GDSC1; GDSC2; CTRP2; CTRP1 2.6631 6.8766 1.8475 19.9125
HCT 15 GDSC1; GDSC2; CTRP2 2.7201 5.4213 2.4321 17.5673
LS1034 GDSC1; GDSC2; CTRP2 2.7363 7.9759 1.4585 21.1761
SW626 GDSC1; GDSC2 2.7656 6.778 1.1109 15.5997
COLO201 CTRP2 2.7697 5.7522 2.3811 17.6074
CL-40 CTRP1 2.8139 8.2994 1.3939 40.5524
CL-11 GDSC1; GDSC2; CTRP2 2.8494 7.5401 1.7647 19.7168
SNU-C2B GDSC1; GDSC2 2.9874 8.0376 0.6798 17.3805
NCI-H508 GDSC1; GDSC2; CTRP2; CTRP1 3.0137 7.7642 1.8357 19.0074
SW1116 GDSC1; GDSC2 3.1236 6.4066 1.6114 11.3991
SNU-C5 GDSC1; GDSC2; CTRP2; CTRP1 3.1302 6.5932 2.4551 16.3075
DiFi GDSC1; GDSC2 3.1807 6.104 1.8115 9.9738
SW1417 GDSC1; GDSC2; CTRP2 3.1963 7.2683 2.2404 16.9602
SW620 GDSC1; GDSC2; CTRP2; CTRP1 3.3459 7.4716 2.3045 16.318
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 3.3656 7.9699 2.0996 17.0715
SW480 CTRP1 3.3865 8.5154 1.8688 35.1695
SW403 CTRP1 3.4578 6.4663 2.852 29.4054
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 3.4948 7.8032 2.3054 15.9331
LoVo GDSC1; GDSC2; CTRP2; CTRP1 3.5391 6.9224 2.744 14.0871
SW1463 GDSC1; GDSC2 3.6244 8.6054 0.9279 14.0568
SNU-283 GDSC2 3.6375 10.9478 -0.2313 20.111
HT115 GDSC1; GDSC2; CTRP2; CTRP1 3.7328 8.6691 2.1349 16.0224
LS180 GDSC1; GDSC2; CTRP2; CTRP1 3.814 6.4262 3.2417 11.4094
SNU-C2A CTRP1 3.8379 8.5024 2.3158 30.3054
SW837 GDSC1; GDSC2 3.9941 9.0592 0.9924 12.6787
SNU-81 GDSC1; GDSC2; CTRP1 4.0822 5.9464 3.7216 11.1921
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 4.1137 10.6239 1.5424 17.4582
OUMS-23 CTRP2 4.2843 5.6431 4.0554 6.9834
SNU-61 GDSC1; GDSC2; CTRP2; CTRP1 4.2944 8.3184 2.8392 11.8548
LS123 GDSC1; GDSC2; CTRP2; CTRP1 4.3309 8.5114 2.7793 12.018
RKO GDSC1; GDSC2; CTRP2; CTRP1 4.3971 8.5486 2.8225 11.6916
DLD-1 CTRP2; CTRP1 4.4347 5.2898 4.3407 5.4835
SNU-C4 CTRP2; CTRP1 4.4493 6.6005 3.8105 7.5193
HCT 8 CTRP2; CTRP1 4.4749 7.5138 3.3996 9.138
HCC-56 CTRP2 4.5348 10.4484 2.0085 14.7031
SNU-503 CTRP2 4.7243 9.0978 2.8475 10.8774
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 5.7937 11.3708 2.6011 9.8327
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 5.8075 10.9764 2.808 8.9606
⏷ Show the Full List of 63 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 6.1353 7.6542 2.8369 0.1175
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 -0.0986 2.4819 -0.2198 28.8099
SNU-886 CTRP2 1.444 7.0046 0.5007 28.2726
SNU-182 CTRP2 1.5848 6.1336 0.9677 26.2523
Li-7 CTRP2 1.7338 4.1471 1.5175 18.2133
HuH-6 CTRP2 2.4152 6.6361 1.6791 21.2404
HuH-1 GDSC1; GDSC2; CTRP2 2.4471 5.9893 1.9508 20.1409
HLE GDSC1; GDSC2 2.5251 5.6887 1.423 14.5345
SNU-878 CTRP2 2.721 4.4643 2.6549 16.7725
Huh-7 GDSC1; GDSC2 2.7425 6.6692 1.1439 15.4786
JHH-4 GDSC1; GDSC2; CTRP2 2.9906 6.6108 2.3005 17.284
Hep-G2 CTRP2; CTRP1 3.3686 8.0624 2.0603 17.2179
JHH-2 GDSC1; GDSC2; CTRP2 3.4 5.9819 2.9807 13.5505
SNU-449 GDSC1; GDSC2; CTRP2; CTRP1 3.6502 7.2134 2.7292 13.8576
SNU-423 GDSC1; GDSC2; CTRP2 3.7637 6.2163 3.2761 11.411
JHH-7 GDSC1; GDSC2 3.787 8.8535 0.9335 13.5732
JHH-5 CTRP2 3.8446 11.4433 0.893 20.4865
SNU-387 GDSC1; GDSC2; CTRP2 4.0653 6.7715 3.3483 10.3348
JHH-1 GDSC1; GDSC2; CTRP2 4.1104 6.2895 3.6076 9.1898
SNU-475 CTRP2 4.3337 5.4647 4.1736 6.3975
HLF CTRP2 4.3343 5.4795 4.169 6.4127
Hep-G2/C3A GDSC1; GDSC2 4.3503 9.8061 0.8919 12.3463
SNU-398 GDSC1; GDSC2; CTRP2; CTRP1 4.6016 9.0882 2.7428 11.5714
JHH-6 GDSC1; GDSC2; CTRP2; CTRP1 4.6374 5.0982 4.6116 3.8926
SK-HEP-1 GDSC1; GDSC2; CTRP2 4.9151 7.0038 4.0566 5.4358
PLC/PRF/5 CTRP2 5.1747 6.0544 4.7577 1.9635
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 226 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1648 GDSC1; GDSC2 -0.8848 3.0521 -1.1982 43.147
LC-2/ad GDSC1; GDSC2 -0.3116 3.5452 -0.7066 38.0843
COLO 699 CTRP1 -0.2508 12.3755 -3.5428 58.2015
COR-L32 GDSC1; GDSC2 0.0145 4.4734 -0.6566 36.0829
NCI-H2073 CTRP1 0.0204 3.9633 -0.1684 67.5458
NCI-H1975 GDSC1; GDSC2; CTRP2; CTRP1 0.3349 3.3366 0.26 32.6626
HCC1833 CTRP2; CTRP1 0.4941 6.8639 -0.4673 34.277
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 0.6689 4.1747 0.4935 30.7791
NCI-H2228 GDSC1; GDSC2; CTRP2 0.7183 3.75 0.6157 30.2088
NCI-H727 GDSC1; GDSC2; CTRP2; CTRP1 0.7734 4.8857 0.4526 30.5687
NCI-H1437 GDSC1; GDSC2; CTRP1 0.8431 5.6457 0.3184 38.594
NCI-H358 GDSC1; GDSC2; CTRP2; CTRP1 0.8685 5.2368 0.4645 30.2178
HCC1588 CTRP2 0.9237 4.0422 0.7914 28.9454
NCI-H1341 GDSC1; GDSC2; CTRP2 0.9534 4.1086 0.8123 28.7781
HOP-62 GDSC1; GDSC2; CTRP2 0.978 5.8017 0.4172 30.0161
NCI-H292 GDSC1; GDSC2; CTRP2 0.9809 4.4599 0.6064 24.186
NCI-H2009 GDSC1; GDSC2; CTRP2; CTRP1 1.0011 6.1284 0.3366 30.2025
NCI-H1666 GDSC1; GDSC2; CTRP2; CTRP1 1.013 6.5891 0.1907 30.627
Lu-65 GDSC1; GDSC2; CTRP2; CTRP1 1.0932 4.367 0.9161 27.9729
HCC44 GDSC1; GDSC2; CTRP2; CTRP1 1.1314 3.7066 1.0613 27.3544
A-427 GDSC1; GDSC2 1.2333 4.2599 0.7319 23.6579
NCI-H596 GDSC1; GDSC2; CTRP1 1.2631 4.3664 1.1001 33.9588
NCI-H3122 GDSC2 1.3049 5.6536 0.2294 26.007
Lu-99A GDSC1; GDSC2 1.3099 4.6538 0.6595 23.7185
NCI-H2810 GDSC1; GDSC2 1.3125 4.0397 0.8983 22.3953
Lu-99 CTRP2; CTRP1 1.3216 4.8259 1.0647 26.7327
A-549 GDSC1; GDSC2; CTRP2; CTRP1 1.3606 4.5549 1.168 26.252
NCI-H2795 GDSC1; GDSC2 1.3648 4.4074 0.8157 22.6233
HCC78 GDSC1; GDSC2; CTRP2; CTRP1 1.3704 7.1592 0.363 28.9493
NCI-H838 GDSC1; GDSC2; CTRP2 1.3892 4.4438 1.2216 25.9754
CAL-12T GDSC1; GDSC2; CTRP2; CTRP1 1.4053 4.3148 1.2634 25.7799
EMC-BAC-1 GDSC1; GDSC2 1.4785 4.5562 0.877 21.7962
LC-1/sq-SF CTRP2; CTRP1 1.5488 5.8024 1.0381 26.117
LCLC-97TM1 GDSC1; GDSC2; CTRP2; CTRP1 1.5786 10.0382 -0.639 31.2756
NCI-H187 GDSC1 1.59 8.2216 -1.2372 27.101
NCI-H2731 GDSC1; GDSC2 1.6029 4.3261 1.1006 20.0085
PaCa-3 GDSC1; GDSC2 1.6055 4.0922 1.1937 19.4699
UMC-11 GDSC1; GDSC2 1.6249 7.4167 -0.268 27.0729
COLO 668 GDSC1; GDSC2; CTRP2; CTRP1 1.6491 6.7843 0.8034 26.627
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 1.71 4.7149 1.5132 23.9468
NCI-H3255 GDSC1; GDSC2; CTRP1 1.7375 4.1233 1.6522 29.6557
EKVX GDSC1; GDSC2; CTRP2 1.748 6.1009 1.1557 25.0964
COR-L311 GDSC2 1.7616 6.5028 0.298 23.7881
PC-14 GDSC1; GDSC2; CTRP2 1.7704 3.7337 1.7331 22.9947
EMC-BAC-2 GDSC1; GDSC2 1.8173 5.3013 0.9081 20.2299
NCI-H2804 GDSC1; GDSC2 1.9098 4.9559 1.1562 18.4306
HOP-92 GDSC1; GDSC2; CTRP2 1.9203 4.6831 1.7488 22.4616
DMS 454 CTRP2 1.9518 9.0467 0.1833 27.7866
NCI-H2126 CTRP2; CTRP1 1.9824 5.3951 1.6353 22.6728
LOU-NH91 GDSC1; GDSC2; CTRP2 1.987 5.2299 1.6871 22.4733
Lu-134-A GDSC1; GDSC2 2.0395 7.7007 -0.0104 24.2743
COR-L23 GDSC1; GDSC2; CTRP1 2.0644 7.0338 1.1506 30.3748
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 2.0845 8.2268 0.6779 25.7796
NCI-H2869 GDSC1; GDSC2 2.0866 5.5813 1.0491 18.3707
RERF-LC-MS GDSC1; GDSC2; CTRP2 2.1237 4.9823 1.901 21.2913
CPC-N GDSC1; GDSC2 2.1256 8.0574 -0.1042 24.4084
NCI-H1563 GDSC1; GDSC2; CTRP2 2.1284 7.7159 0.9405 24.7429
EPLC-272H GDSC1; GDSC2; CTRP2; CTRP1 2.1339 6.7614 1.3306 23.3286
NCI-H647 GDSC2; CTRP2 2.1618 4.3697 2.0694 20.5809
NCI-H1944 GDSC1; GDSC2; CTRP2; CTRP1 2.1761 6.2784 1.556 22.3838
NCI-H1568 GDSC1; GDSC2; CTRP2; CTRP1 2.18 5.2073 1.9039 21.1081
HCC827 GDSC1; GDSC2; CTRP2; CTRP1 2.1943 4.1238 2.1394 20.236
COR-L303 GDSC2 2.2312 5.6525 1.1576 17.1905
NCI-H2087 GDSC1; GDSC2; CTRP2 2.2444 7.6565 1.0865 23.8941
NCI-H1792 GDSC1; GDSC2; CTRP2; CTRP1 2.2503 6.6939 1.4808 22.4444
NCI-H847 GDSC1; GDSC2 2.263 7.8795 0.11 22.8646
T3M-10 CTRP2; CTRP1 2.3033 5.0773 2.073 20.1258
SK-LU-1 GDSC1; GDSC2; CTRP2; CTRP1 2.3249 5.6622 1.9271 20.5875
NCI-H1734 GDSC2; CTRP2 2.3488 5.4284 1.7387 15.4225
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 2.3585 7.3003 1.354 22.6022
NCI-H1048 GDSC1; GDSC2; CTRP1 2.4023 4.9977 2.201 24.5646
HCC1171 CTRP2 2.409 6.8141 1.6031 21.54
NCI-H1355 GDSC1; GDSC2; CTRP2; CTRP1 2.425 8.6825 0.8274 24.3091
NCI-H1963 GDSC1; GDSC2; CTRP1 2.4432 6.9859 1.5711 27.1891
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 2.4887 4.1908 2.4439 18.244
COR-L105 GDSC1; GDSC2; CTRP2 2.52 5.6563 2.1412 19.2261
NCI-H2171 GDSC1; GDSC2; CTRP2 2.5257 6.5433 1.8327 20.3539
NCI-H1781 GDSC1; GDSC2; CTRP1 2.5904 4.5883 2.4936 22.516
NCI-H2373 GDSC1; GDSC2 2.595 7.8619 0.4209 20.0918
NCI-H1793 GDSC1; GDSC2; CTRP2; CTRP1 2.601 8.0354 1.2935 22.1535
SBC-3 GDSC1; GDSC2 2.6184 7.4897 0.6262 18.8911
LK-2 GDSC1; GDSC2 2.6404 6.5279 1.1207 15.9607
NCI-H1299 GDSC1; GDSC2; CTRP2; CTRP1 2.6899 6.1567 2.1534 18.6859
NCI-H1703 GDSC1; GDSC2; CTRP2 2.7125 4.9776 2.5441 17.1875
HCC2108 CTRP2; CTRP1 2.766 6.6294 2.055 18.8412
NCI-H1876 GDSC1; GDSC2; CTRP1 2.7733 7.6148 1.6539 25.6124
HCC4006 CTRP2; CTRP1 2.7737 5.1242 2.574 16.8927
LUDLU-1 CTRP2 2.8072 6.3651 2.2015 18.1717
NCI-H2286 CTRP2; CTRP1 2.8109 5.1128 2.6176 16.6226
HCC2279 CTRP2 2.8261 5.4197 2.548 16.8279
NCI-H510A GDSC1; GDSC2 2.8263 5.1996 1.9437 10.2813
NCI-H1650 GDSC1; GDSC2; CTRP2 2.8334 6.0416 2.3495 17.5406
ABC-1 GDSC1; GDSC2 2.8588 8.621 0.2772 19.9746
HCC366 GDSC1; GDSC2; CTRP2 2.8622 7.7133 1.2177 16.2353
NCI-H720 GDSC1; GDSC2 2.8968 7.2643 0.9862 15.9092
NCI-H524 GDSC1; GDSC2; CTRP2 2.9057 9.8737 0.7599 23.2619
NCI-H2106 CTRP2 2.9068 8.3677 1.4572 20.7274
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2; CTRP1 2.921 8.3276 1.4896 20.5685
IST-SL2 GDSC1; GDSC2 2.9336 7.1421 1.0793 15.2408
IST-SL1 GDSC1; GDSC2 2.9426 4.5551 2.3663 7.2515
SK-MES-1 GDSC1; GDSC2; CTRP2 2.945 4.9954 2.7932 15.5838
NCI-H23 GDSC1; GDSC2; CTRP2; CTRP1 2.9523 6.9636 2.1162 18.0943
HCC95 CTRP2 2.9536 6.59 2.2697 17.5037
NCI-H2030 GDSC1; GDSC2; CTRP2; CTRP1 2.9638 7.5477 1.8795 18.9717
DMS 114 GDSC1; GDSC2; CTRP2 2.9645 7.2007 2.0294 18.3943
NCI-H2803 GDSC1; GDSC2 2.9897 6.1274 1.6335 11.6803
NCI-H211 GDSC1; GDSC2; CTRP2 2.9951 6.7831 2.2356 17.5198
NCI-H810 GDSC1; GDSC2; CTRP2; CTRP1 2.9985 5.0209 2.8453 15.2331
NCI-H1688 GDSC1; GDSC2 3.0077 9.0617 0.1862 19.9661
NCI-H1836 GDSC1; GDSC2; CTRP1 3.0103 6.9617 2.1777 22.3987
DV-90 CTRP2; CTRP1 3.0396 5.4233 2.7797 15.3451
NCI-H2461 GDSC1; GDSC2 3.0426 7.8601 0.8161 16.4329
NCI-H1581 GDSC1; GDSC2; CTRP2 3.0512 7.0628 2.178 17.5889
HCC2935 CTRP2; CTRP1 3.0594 6.0272 2.5981 15.9611
SW1271 GDSC1; GDSC2; CTRP2 3.073 6.2728 2.5207 16.2155
NCI-H2818 GDSC1; GDSC2 3.0787 5.3974 2.0751 8.6298
RERF-LC-Sq1 GDSC1; GDSC2 3.0966 7.4603 1.0621 14.83
NCI-H2085 GDSC1; GDSC2; CTRP2 3.1141 4.883 3.0029 14.3163
DMS 53 GDSC1; GDSC2; CTRP2 3.1583 8.6561 1.5773 19.6214
HCC1359 CTRP1 3.1845 4.2908 3.1668 29.0553
NCI-H2066 GDSC1; GDSC2 3.1916 8.1751 0.7859 16.1434
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 3.2014 10.4439 0.7754 22.4549
NCI-H322M GDSC1; GDSC2 3.2067 8.1184 0.827 15.8626
NCI-H1184 CTRP2 3.2394 6.0721 2.7748 14.7836
IA-LM GDSC1; GDSC2 3.2416 6.4029 1.714 10.4013
NCI-H2369 GDSC1; GDSC2 3.2946 5.4449 2.2376 6.945
NCI-H835 GDSC1; GDSC2 3.3035 5.9686 1.9833 8.5259
NCI-H1623 GDSC1; GDSC2; CTRP2 3.3406 7.4192 2.3223 16.2617
Lu-135 GDSC1; GDSC2 3.3681 5.2844 2.3789 5.8375
NCI-H209 GDSC1; GDSC2 3.3685 4.7395 2.6515 4.1111
NCI-H2135 GDSC1; GDSC2 3.3839 7.5645 1.2521 12.828
NCI-H290 GDSC1; GDSC2 3.4031 6.2517 1.9242 8.6111
NCI-H64 GDSC1; GDSC2 3.4189 4.3199 2.9013 2.3944
NCI-H1373 CTRP2; CTRP1 3.45 7.589 2.3575 15.8412
SBC-1 GDSC1; GDSC2 3.4656 5.2642 2.4678 5.0047
NCI-H2170 GDSC1; GDSC2; CTRP2 3.4781 8.093 2.1555 16.5677
LC-1/sq GDSC1; GDSC2 3.5139 8.0637 1.1091 13.3088
NCI-H2591 GDSC1; GDSC2 3.5274 6.4574 1.922 8.2776
NCI-H1869 GDSC1; GDSC2; CTRP2 3.5288 6.3559 2.9718 13.2271
NCI-H1838 GDSC1; GDSC2; CTRP2 3.535 7.4888 1.9556 11.3695
NCI-H2405 GDSC1; GDSC2; CTRP2; CTRP1 3.5409 7.5219 2.4796 15.1265
NCI-H2722 GDSC1; GDSC2 3.5549 5.9545 2.1944 6.489
NCI-H650 GDSC1; GDSC2; CTRP2; CTRP1 3.5588 6.5995 2.9025 14.4354
NCI-H1693 GDSC1; GDSC2; CTRP2 3.5669 5.7006 3.2622 12.0152
NCI-H1573 GDSC1; GDSC2; CTRP2; CTRP1 3.569 9.4475 1.6054 18.4912
COR-L321 GDSC1; GDSC2 3.5717 4.9593 2.7009 3.2625
NCI-H1435 GDSC1; GDSC2; CTRP2; CTRP1 3.5802 7.4236 2.5638 14.6926
NCI-H513 GDSC1; GDSC2 3.5864 7.9807 1.2091 12.5076
NCI-H446 GDSC1; GDSC2; CTRP2 3.6055 8.6989 1.9972 16.8763
Sq-1 CTRP2; CTRP1 3.6105 7.2131 2.6889 14.1191
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 3.657 5.9631 3.263 11.756
NCI-H1993 GDSC1; GDSC2 3.7011 6.1425 2.2138 5.9867
COR-L51 CTRP2; CTRP1 3.7141 6.0318 3.2973 11.466
NCI-H2029 GDSC1; GDSC2; CTRP2; CTRP1 3.723 7.158 2.8278 13.2799
NCI-H2595 GDSC1; GDSC2 3.7416 5.7118 2.4562 4.3751
NCI-H146 GDSC1; GDSC2 3.7625 5.6586 2.4973 4.0712
NCI-H69 GDSC1; GDSC2; CTRP2 3.8154 7.7548 2.6467 13.7727
Calu-3 GDSC1; GDSC2; CTRP2; CTRP1 3.8158 6.3044 3.2946 11.1981
NCI-H2347 GDSC1; GDSC2 3.8207 7.9892 1.3898 10.7815
LCLC-103H GDSC1; GDSC2; CTRP2; CTRP1 3.844 5.9074 3.4839 11.183
COR-L95 GDSC1; CTRP2 3.8714 8.8005 2.2054 15.4099
NCI-H250 GDSC2 3.893 7.0794 1.8953 7.4919
RERF-LC-Ad2 CTRP2 3.9314 6.3862 3.3806 10.5537
NCI-H2227 GDSC1; GDSC2 3.9558 6.8302 2.0639 6.2969
NCI-H1155 GDSC1; GDSC2; CTRP2 4.0026 6.0149 3.6098 9.4705
NCI-H1930 CTRP1 4.0236 5.2113 3.9148 17.7564
NCI-H82 GDSC1; GDSC2; CTRP1 4.0299 5.7698 3.7351 11.3104
NCI-H661 GDSC1; GDSC2; CTRP2; CTRP1 4.034 7.3414 3.0552 11.5904
NCI-H2291 GDSC1; GDSC2; CTRP2 4.045 9.8483 1.226 13.431
NCI-H841 GDSC1; GDSC2; CTRP2; CTRP1 4.0471 8.8187 2.3636 14.3616
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 4.048 7.8711 2.8195 12.5109
VMRC-LCD GDSC1; GDSC2; CTRP2; CTRP1 4.0555 6.1784 3.5978 9.3741
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 4.0561 7.3995 3.0499 11.5573
NCI-H2172 GDSC1; GDSC2; CTRP2; CTRP1 4.0721 8.3122 2.6318 13.2163
NCI-H1436 GDSC1; GDSC2 4.0793 6.076 2.5134 3.2905
NCI-H748 GDSC1; GDSC2 4.1138 7.6894 1.7578 7.8032
MOR/CPR CTRP2 4.1228 4.944 4.084 7.3586
BEN GDSC1; GDSC2; CTRP2; CTRP1 4.1373 6.7933 3.4109 9.9026
RERF-LC-A1 CTRP2 4.1456 6.6895 3.4664 9.6594
NCI-H522 GDSC1; GDSC2; CTRP2; CTRP1 4.1688 7.0068 3.3441 10.0925
RERF-LC-KJ GDSC1; GDSC2; CTRP1 4.1956 8.3048 2.7527 15.7388
HCC33 GDSC1; GDSC2; CTRP1 4.2479 6.0066 3.871 9.8882
NCI-H2141 GDSC1; GDSC2; CTRP1 4.257 8.1226 2.8989 14.8138
NCI-H740 GDSC2 4.2713 8.6801 1.3869 9.6648
NCI-H526 GDSC1; GDSC2; CTRP2 4.2787 9.8218 1.4341 12.0404
NCI-H1339 CTRP2 4.2977 6.1091 3.8789 7.6305
Ms-1 GDSC1; GDSC2 4.3002 9.8545 0.8307 12.815
NCI-H1770 GDSC1; GDSC2 4.3082 12.0301 -0.24 18.3132
NCI-H1105 GDSC1; GDSC2; CTRP2; CTRP1 4.3112 7.5018 3.2495 10.134
NCI-H128 GDSC1 4.3324 6.7928 1.488 2.2103
COR-L279 GDSC1; GDSC2; CTRP1 4.3405 5.8769 4.0218 8.8277
NCI-H1651 GDSC1; GDSC2; CTRP2 4.3444 6.6662 3.6762 8.3196
ChaGo-K-1 GDSC1; GDSC2; CTRP2; CTRP1 4.3485 6.5152 3.7497 8.0139
NCI-H1395 CTRP2 4.3815 7.7804 3.1823 10.2464
DMS 79 GDSC1; GDSC2; CTRP2 4.4297 6.9114 3.6453 8.2375
LB647-SCLC GDSC1; GDSC2 4.438 8.2703 1.7048 7.3822
Lu-139 GDSC1 4.4436 6.2604 1.7505 0.7624
SCLC-21H CTRP1 4.4597 5.4191 4.3258 11.7403
Calu-6 GDSC1; GDSC2; CTRP2; CTRP1 4.4666 7.6173 3.3416 9.3957
HCC1438 CTRP2 4.5131 11.8072 1.3137 17.4467
NCI-H1915 GDSC1; GDSC2; CTRP2; CTRP1 4.5243 6.9298 3.7279 7.6755
NCI-H1304 GDSC1 4.5395 6.0054 1.8812 0.2971
DMS 273 GDSC1; GDSC2; CTRP2; CTRP1 4.5598 6.0391 4.1784 5.7657
HCC1195 CTRP2; CTRP1 4.568 10.4655 2.0295 14.5482
COR-L88 GDSC1; GDSC2; CTRP1 4.5984 6.4784 4.0142 8.0325
EBC-1 GDSC1; GDSC2; CTRP2; CTRP1 4.6106 7.205 3.6773 7.6836
NCI-H2444 GDSC1; GDSC2 4.612 6.132 2.7908 1.0001
NCI-H322 CTRP2 4.6485 7.103 3.7625 7.2458
LK2 CTRP2 4.6822 5.6061 4.4923 4.2085
NCI-H196 GDSC1; GDSC2; CTRP2 4.9365 7.8256 2.9348 4.1661
NCI-H520 GDSC1; GDSC2; CTRP2 5.0405 8.308 3.5172 7.4321
SW1573 GDSC1; GDSC2; CTRP2 5.0662 12.4126 1.4878 15.636
NCI-H2023 GDSC1; GDSC2; CTRP2; CTRP1 5.0906 11.4562 1.9865 13.6415
Calu-1 CTRP2 5.1714 12.0658 1.7495 14.4157
NCI-H1092 GDSC1; GDSC2 5.1995 13.4102 -0.2559 16.1988
NCI-H2196 GDSC1; GDSC2; CTRP2 5.2005 6.1506 4.7314 2.0229
KNS-62 GDSC1; GDSC2; CTRP2; CTRP1 5.3659 7.3213 4.281 3.6045
NCI-H345 GDSC1; GDSC2 5.6638 15.7502 -1.0651 18.6111
Lu-165 GDSC1; GDSC2 5.74 13.0803 0.2811 12.4404
RERF-LC-Ad1 CTRP2 5.7796 15.7427 -0.3358 16.1906
SBC-5 GDSC1; GDSC2; CTRP2 5.7889 6.9943 4.7412 1.0888
NCI-H889 CTRP2 5.8724 12.7447 1.979 12.1923
NCI-H1694 GDSC1; GDSC2; CTRP2; CTRP1 5.9087 13.8666 1.4489 14.1708
NCI-H226 GDSC1; GDSC2; CTRP2 5.9852 13.3107 1.7858 12.7455
SHP-77 GDSC1; GDSC2; CTRP2; CTRP1 7.0735 14.6074 1.9588 10.2748
Hs 888.Lu CTRP2 3.856 5.9777 3.4694 10.4136
⏷ Show the Full List of 226 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 4.8264 7.7765 2.1885 3.8002
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.0261 7.9893 1.7482 19.3104
RMUG-S CTRP1 -0.7975 8.6838 -2.5389 63.4554
OVKATE GDSC1; GDSC2; CTRP1 0.7498 2.7804 0.7351 37.686
DOV13 GDSC1; GDSC2 1.5809 3.5807 1.3454 18.728
IGROV-1 GDSC1; GDSC2; CTRP2; CTRP1 1.8482 4.9489 1.609 23.1786
OVCAR-5 GDSC1; GDSC2; CTRP2 2.0806 7.7139 0.8913 25.0524
FU-OV-1 GDSC1; GDSC2; CTRP2 2.1131 9.1346 0.3084 26.9267
OVTOKO GDSC1; GDSC2; CTRP2 2.2774 5.5614 1.6091 16.1681
RMG-I GDSC1; GDSC2; CTRP2; CTRP1 2.565 6.8059 1.7719 20.4706
COV434 CTRP2; CTRP1 2.8234 6.7064 2.0853 18.5665
JHOS-4 GDSC2; CTRP1 2.8369 7.6569 1.7013 25.1766
Caov-4 GDSC1; GDSC2 2.8868 6.0784 1.5662 12.4294
SNU-119 CTRP2 3.0347 6.3318 2.4571 16.5644
JHOM-1 CTRP2; CTRP1 3.1075 6.1727 2.5957 15.8339
A2780 GDSC1; GDSC2; CTRP2; CTRP1 3.1114 5.4918 2.8369 14.922
COV362 CTRP2; CTRP1 3.1214 6.6544 2.421 16.4625
HEY A8 CTRP2; CTRP1 3.1471 5.9969 2.7035 15.3149
OVCAR-4 GDSC1; GDSC2; CTRP2; CTRP1 3.159 7.0335 2.3026 16.8178
OVCAR-8 GDSC1; GDSC2; CTRP2; CTRP1 3.2975 4.8438 3.2101 13.0139
OC 314 GDSC1; GDSC2; CTRP2 3.3128 5.4451 3.0707 13.4677
OVSAHO CTRP2 3.3147 6.6968 0.8003 5.0592
OV7 CTRP2; CTRP1 3.3443 6.0668 2.8891 14.0546
SNU-840 CTRP2; CTRP1 3.3863 7.2096 2.4614 15.5972
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 3.4286 6.5501 2.7868 14.2147
ES-2 GDSC1; GDSC2 3.4957 5.1055 2.5705 4.2756
SNU-8 CTRP2 3.5068 6.2351 2.997 13.1903
OVISE GDSC1; GDSC2 3.5299 9.6491 0.33 17.6324
OVCAR-3 GDSC1; GDSC2 3.7073 7.4918 1.5488 10.1123
COV644 CTRP2; CTRP1 3.7634 8.024 2.4696 14.6109
Caov-3 GDSC2; CTRP2; CTRP1 3.8802 6.3428 3.3458 10.8259
SK-OV-3 GDSC1; GDSC2; CTRP2; CTRP1 3.9263 5.9841 3.5415 9.9431
OAW28 GDSC1; GDSC2; CTRP2 3.9434 8.7003 2.3223 14.7707
JHOS-2 GDSC1; GDSC2; CTRP2 4.0044 6.5313 3.3932 10.3126
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 4.0117 6.5147 3.408 10.2349
OAW42 GDSC1; GDSC2; CTRP2; CTRP1 4.0455 7.9926 2.7593 12.7612
Kuramochi GDSC1; GDSC2; CTRP2 4.1862 9.5246 1.5061 11.9185
MCAS CTRP2 4.3923 7.0347 3.5504 8.7133
OVK18 GDSC1; GDSC2; CTRP2; CTRP1 4.4834 6.9859 3.6618 8.0425
JHOC-5 CTRP2; CTRP1 4.6592 7.6763 3.492 8.341
ONCO-DG-1 CTRP2 4.7527 7.262 3.0785 3.8363
EFO-21 GDSC1; GDSC2; CTRP2; CTRP1 4.7868 7.1104 3.8873 6.4192
OV56 GDSC1; GDSC2; CTRP2 4.8078 6.9864 3.9675 6.0401
TOV-21G GDSC1; GDSC2; CTRP2 4.8886 5.5983 4.7096 2.81
TOV-112D GDSC1; GDSC2; CTRP2 4.915 6.3232 4.3915 4.0448
EFO-27 GDSC1; GDSC2; CTRP2; CTRP1 5.1085 12.5239 1.4677 15.6277
OVMANA CTRP1 5.1654 6.1469 4.7035 4.746
COV318 CTRP1 5.5862 9.0175 3.6096 12.7367
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 3.4731 6.8119 2.7234 14.3423
H-STS CTRP2 4.205 6.5401 3.5939 8.9995
P-STS CTRP2 5.5517 7.1981 4.484 2.4446
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 4.829 7.9726 3.4993 7.9432
Rh41 GDSC1; GDSC2; CTRP2 -1.9003 0.0707 -1.9009 47.2806
Rh30 GDSC1; GDSC2 -0.1038 3.7617 -0.5454 36.3078
STS-0421 GDSC1; GDSC2 0.7299 3.9575 0.2972 28.2443
Tm87-16 CTRP2 0.9221 4.8766 0.617 29.5377
G-401 GDSC1; GDSC2; CTRP2; CTRP1 1.4139 5.0347 1.1137 26.2718
SW872 GDSC1; GDSC2 1.46 3.4697 1.2478 19.8095
Hs 633.T GDSC1; GDSC2 1.5709 3.799 1.2623 19.2348
EW-8 GDSC1; GDSC2 1.6706 5.4634 0.6866 22.0634
SW982 GDSC1; GDSC2; CTRP2 1.8419 4.5321 1.6946 22.898
RD GDSC1; GDSC2; CTRP2 1.9566 6.0858 1.3868 23.6453
Rh18 GDSC1; CTRP2 2.2094 7.1622 1.253 23.3934
TTC-709 CTRP2 2.2355 5.9972 1.7191 21.6126
MFH-ino GDSC1; GDSC2 2.8209 4.8014 2.1321 9.1286
GCT GDSC1; GDSC2; CTRP2 2.925 5.9905 2.4665 16.8396
G-402 GDSC1; GDSC2; CTRP2 2.9974 7.0143 2.1422 17.872
A-204 GDSC1; GDSC2; CTRP2 3.1659 7.1295 2.2689 16.9299
BT-16 CTRP2 3.3873 6.494 2.7665 14.4051
TE 441.T GDSC1; GDSC2; CTRP2 3.6119 8.3047 2.1892 16.1013
SW684 GDSC1; GDSC2 3.7683 5.2954 2.6778 2.9487
Hs 729.T CTRP2 3.8896 5.6999 3.6106 9.7829
RKN GDSC1; GDSC2; CTRP2; CTRP1 3.9085 7.3325 2.9349 12.3847
VA-ES-BJ GDSC1; GDSC2 3.9433 8.7772 1.0932 12.2258
TE 617.T CTRP2 4.2062 6.6629 3.5396 9.2136
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 4.2969 7.525 3.2247 10.2694
SK-LMS-1 GDSC1; GDSC2; CTRP2 4.48 9.5071 2.426 13.1349
KYM-1 GDSC1; GDSC2; CTRP2 4.669 10.7142 1.9947 14.4727
MES-SA GDSC1; GDSC2; CTRP2 4.7989 5.3139 4.7291 2.9797
SK-UT-1 GDSC1; GDSC2; CTRP2 5.1188 8.2902 3.5929 6.9591
BT-12 CTRP2 5.2096 5.9082 4.8602 1.4652
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.9429 5.9003 4.6228 3.0279
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1; GDSC2; CTRP2 1.7213 4.5045 1.5695 23.7149
MSTO-211H GDSC1; GDSC2; CTRP2; CTRP1 1.9806 4.7096 1.8085 22.0633
NCI-H28 GDSC1; GDSC2; CTRP2; CTRP1 2.1423 6.2484 1.5303 22.5768
MPP 89 GDSC1; GDSC2; CTRP2 2.1883 4.3569 2.1 20.3907
NCI-H2452 GDSC1; GDSC2; CTRP2 2.8265 5.4433 2.5414 16.8508
JL-1 CTRP2 2.8719 5.7233 2.5017 16.8625
ACC-MESO-1 CTRP2 3.3287 5.5366 3.059 13.4635
NCI-H2052 GDSC2; CTRP2; CTRP1 4.5297 11.4032 1.5293 16.5922
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; GDSC2; CTRP2 0.9637 5.6726 0.4416 29.9831
DU145 GDSC1; GDSC2; CTRP2 3.9095 5.9827 3.5243 10.0553
22Rv1 GDSC1; GDSC2 4.4794 14.4623 -1.3155 22.3833
LNCaP clone FGC GDSC1; GDSC2; CTRP2 4.5721 7.9937 3.256 9.5115
PC-3 GDSC1; GDSC2 4.9193 8.2378 2.0332 4.5106
NCI-H660 GDSC2 5.2247 6.8322 2.7882 0.5255
PaCa-3 CTRP2; CTRP1 5.2556 8.5064 3.5992 6.6673
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 0.7425 4.0708 0.456 25.5463
A-253 GDSC1; GDSC2; CTRP2 4.7525 7.6924 3.5692 7.8157
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -0.7633 1.2269 -0.7831 41.0818
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GCIY GDSC1; GDSC2 -0.3437 4.0492 -0.8983 38.919
RERF-GC-1B GDSC1; GDSC2 -0.2637 2.5817 -0.4168 36.6788
HSC-39 GDSC1; GDSC2 -0.0687 2.0809 -0.128 34.3152
SNU-16 GDSC1; GDSC2; CTRP2 0.5055 3.4247 0.4306 31.5301
OCUM-1 GDSC2; CTRP2 0.7773 6.8175 -0.1454 32.4158
ECC10 GDSC1; GDSC2; CTRP2 1.2834 6.3951 0.5511 28.6037
TMK-1 GDSC1; GDSC2 1.4516 4.5527 0.85 22.0611
MKN28 GDSC2 2.0657 5.9062 0.8763 19.4503
KATO III GDSC1; GDSC2; CTRP2 2.3756 6.9307 1.5215 21.937
SNU-668 CTRP2 2.5007 7.9773 0.7436 19.1587
Fu97 GDSC1; GDSC2; CTRP2; CTRP1 2.5786 6.4327 1.9313 19.8346
HGC-27 GDSC1; GDSC2; CTRP2 2.6678 4.537 2.5861 17.1798
HuG1-N CTRP2 2.9545 7.6426 1.8285 19.1923
GSS CTRP2 2.9763 7.88 1.2457 15.8265
SNU-216 CTRP2 3.0671 5.682 2.7272 15.4569
SK-GT-2 GDSC1; GDSC2 3.0693 4.6986 2.4132 6.533
23132/87 GDSC1; GDSC2; CTRP2 3.0826 5.2634 2.8734 14.8754
AGS GDSC2; CTRP2; CTRP1 3.2618 5.5607 2.9786 13.957
SNU-1 GDSC1; GDSC2; CTRP2 3.4164 6.5966 2.7548 14.3716
MKN1 GDSC1; GDSC2; CTRP2 3.4377 6.2186 2.9303 13.6369
ECC12 GDSC2; CTRP2 3.4697 5.5169 3.2187 12.4599
LMSU CTRP2 3.558 5.1528 3.4223 11.4545
SNU-601 CTRP2 3.5598 7.6147 2.4565 15.1702
SCH GDSC1; GDSC2 3.5835 5.5589 2.4132 5.0366
KE-39 CTRP2 3.6991 9.5387 1.6859 17.8676
IM95 GDSC1; GDSC2; CTRP2 3.8752 7.2039 2.9605 12.3649
NCI-N87 GDSC1; GDSC2; CTRP2 4.0017 6.8461 3.2503 10.887
SNU-620 CTRP2 4.1102 5.4416 3.4837 3.2188
MKN7 GDSC1; GDSC2; CTRP2; CTRP1 4.1976 6.2235 3.7262 8.4946
TGBC11TKB GDSC1; GDSC2 4.2107 8.3733 1.4932 9.1746
Hs 746.T GDSC1; GDSC2; CTRP2 4.414 5.8649 4.1038 6.4412
RF-48 GDSC1; GDSC2 4.5132 12.2535 -0.1941 17.5701
MKN74 CTRP2; CTRP1 4.5236 8.4028 3.0105 10.6349
GSU CTRP2 4.6903 5.5198 4.5358 4.0181
NUGC-4 GDSC1; GDSC2; CTRP2; CTRP1 4.6983 5.7985 4.4266 4.4237
NUGC-3 GDSC1; GDSC2; CTRP2 4.7298 6.4134 4.1725 5.3724
SH-10-TC CTRP2; CTRP1 4.7356 5.6878 4.5134 3.9837
SNU-5 GDSC1; GDSC2; CTRP2 4.9085 5.5906 4.7333 2.6652
SNU-719 CTRP2 5.1431 13.5097 1.0039 17.2815
MKN45 GDSC1; GDSC2; CTRP2 5.7242 7.1277 3.6997 0.3839
SNU-1077 CTRP2 2.5802 5.4011 1.9931 13.6907
SNU-685 CTRP2 4.5312 5.8314 4.2401 5.5962
SNG-M GDSC1; GDSC2; CTRP2; CTRP1 4.6396 6.7612 3.9193 6.6212
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1; GDSC2 0.6588 3.7089 0.3014 28.5613
TT GDSC1; GDSC2; CTRP2 1.5689 6.2278 0.9182 26.4733
HTC-C3 GDSC1; GDSC2 1.8514 4.8665 1.1355 18.7836
CGTH-W-1 GDSC1; GDSC2; CTRP2 2.1204 3.3031 2.117 20.5533
B-CPAP GDSC1; GDSC2; CTRP2 2.2147 4.1149 2.1621 20.0923
K5 GDSC1; GDSC2 2.2801 5.8924 1.091 17.4048
8305C GDSC1; GDSC2; CTRP2 2.4225 5.4856 2.0883 19.7095
ASH-3 GDSC1; GDSC2 2.5754 4.3584 2.0998 10.2224
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 2.7259 5.876 2.2917 18.0666
SW579 CTRP2 2.8913 4.5544 2.8237 15.6454
IHH-4 GDSC1; GDSC2 2.8916 7.1346 1.0461 15.5727
BHT-101 GDSC1; GDSC2; CTRP2 2.8966 6.929 1.6252 14.3963
CAL-62 GDSC1; GDSC2; CTRP2 3.3307 6.429 2.7331 14.6887
8505C GDSC1; GDSC2; CTRP2 3.508 6.3825 2.9391 13.41
WRO GDSC1; GDSC2 4.0976 7.1638 2.0028 6.3422
TT2609-C02 GDSC1; GDSC2; CTRP2 4.4197 7.3339 3.434 9.1246
FTC-238 CTRP2 4.4634 5.8093 4.1787 6.0172
FTC-133 GDSC1; GDSC2; CTRP2 5.8626 8.5514 4.0466 3.7552
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB771-HNC GDSC1; GDSC2 -0.7043 3.3873 -1.09 41.6842
YD-10B CTRP2 -0.4142 2.6559 -0.5156 33.1048
NCI-H3118 GDSC1; GDSC2 -0.2879 4.236 -0.9003 38.6028
BB49-HNC GDSC1; GDSC2 0.2222 2.7116 0.0841 31.7934
DOK GDSC1; GDSC2 0.3034 3.4263 -0.0013 31.7947
BB30-HNC GDSC1; GDSC2 0.4799 2.6838 0.3684 29.0867
JHU-011 GDSC1; GDSC2 0.7817 4.161 0.2825 28.0751
SAT [Human HNSCC] GDSC2 0.9685 5.7925 -0.1767 29.4266
BICR 16 CTRP2 0.993 9.4333 -0.9708 33.9109
KON GDSC1; GDSC2 1.1329 2.9407 1.0253 22.5239
Ca9-22 GDSC1; GDSC2 1.3042 5.2928 0.3862 25.2032
PCI-38 GDSC1 1.3716 3.1652 0.8365 11.7364
YD-8 CTRP2 1.5297 3.3782 1.5088 24.5401
SNU-1041 CTRP2 1.7572 4.1005 1.5555 17.99
HSC-3 GDSC1; GDSC2; CTRP2 1.8008 4.2398 1.3448 14.664
JHU-029 GDSC1; GDSC2 1.8113 5.076 1.0024 19.7136
SAS GDSC1; GDSC2 1.8412 4.1211 1.4344 17.0965
BICR 31 GDSC2; CTRP2 1.8485 4.1584 1.7659 22.6299
PE/CA-PJ49 CTRP2 1.9015 5.1046 1.6275 22.9484
Detroit 562 GDSC1; GDSC2 2.019 4.7794 1.3457 16.8877
HO-1-u-1 GDSC1; GDSC2 2.1751 5.1477 1.3379 16.3292
SNU-1076 CTRP2 2.1836 5.454 1.8374 21.3365
KOSC-2 GDSC1; GDSC2 2.2079 4.3509 1.7265 13.8889
HO-1-N-1 GDSC1; GDSC2 2.2199 5.7349 1.1076 17.5279
PCI-04B GDSC1; GDSC2 2.2683 5.0806 1.4617 15.2357
SCC-9 GDSC1; GDSC2; CTRP2; CTRP1 2.2704 6.46 1.5909 21.9819
CAL-27 GDSC1; GDSC2; CTRP2 2.3368 5.4831 1.9956 20.3029
HSC-2 GDSC1; GDSC2; CTRP2; CTRP1 2.3748 4.3373 2.303 19.094
PCI-15A GDSC1; GDSC2 2.4096 4.088 2.0478 11.1838
PCI-06A GDSC1; GDSC2 2.4609 5.4755 1.4642 14.5127
BICR 10 GDSC1; GDSC2 2.4788 3.7827 2.245 9.7487
BHY GDSC1; GDSC2; CTRP2 2.5121 5.1377 2.2851 18.7276
OSC-19 GDSC1; GDSC2 2.5672 5.0133 1.787 12.1579
SCC-15 GDSC1; GDSC2 2.5737 7.4562 0.6023 19.1764
JHU-022 GDSC1; GDSC2 2.6136 7.1222 0.8034 17.907
SCC-25 GDSC1; GDSC2 2.6215 5.5695 1.5718 13.2868
SCC-4 GDSC1; GDSC2; CTRP2 2.6291 6.812 1.8374 20.0451
CAL-33 GDSC1; GDSC2; CTRP2 2.6327 6.0821 2.1187 18.98
HSC-4 GDSC1; GDSC2; CTRP2 2.6661 6.3374 2.061 19.1
BICR 78 GDSC1; GDSC2 3.2271 9.4663 0.1704 19.3631
SKN-3 GDSC1; GDSC2 3.2271 8.764 0.5215 17.51
PCI-30 GDSC1; GDSC2 3.3031 5.327 2.3036 6.5024
SNU-46 CTRP2 3.3284 6.7447 2.1281 11.1044
BICR 56 CTRP2 3.4819 6.3456 2.9265 13.53
OSC-20 GDSC1; GDSC2 3.5586 5.8636 2.2425 6.1761
BICR 18 CTRP2 3.6164 5.7211 3.3084 11.6997
FaDu GDSC1; GDSC2; CTRP2 3.6389 7.5178 2.5802 14.4785
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 3.8009 6.014 3.3965 10.8455
BICR 6 CTRP2 3.9049 7.5649 2.8235 12.8414
PE/CA-PJ41 (clone D2) CTRP2 3.9622 6.0325 3.5601 9.7728
PE/CA-PJ34 (clone C12) CTRP2 4.0023 6.9253 3.2151 11.0261
SNU-899 CTRP2 4.0991 6.1581 3.1162 4.8978
BICR 22 GDSC1; GDSC2; CTRP2 4.1026 6.1261 3.6691 8.9701
UPCI-SCC-090 GDSC1; GDSC2 4.3821 8.289 1.6568 7.794
SNU-1066 CTRP2 4.9948 8.4488 2.6729 5.219
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-1 CTRP2 0.5572 3.4726 0.4798 31.1948
JMSU-1 CTRP2 0.7442 3.345 0.691 29.8715
RT-112 GDSC1; GDSC2; CTRP2 0.8772 4.3631 0.6829 29.4626
U-BLC1 CTRP2 1.541 8.8116 -0.1361 29.9732
BFTC-905 GDSC1; GDSC2; CTRP2 2.0728 4.7859 1.892 21.4812
SW780 GDSC1; GDSC2 2.1116 5.9382 0.906 19.1072
HT-1376 GDSC1; GDSC2; CTRP2; CTRP1 2.1206 5.4321 1.7752 21.7511
TCCSUP GDSC1; GDSC2; CTRP2 2.1977 4.5174 2.0825 20.4214
5637 GDSC1; GDSC2; CTRP2; CTRP1 2.4372 5.0658 2.222 19.1827
RT-4 GDSC1; GDSC2; CTRP2; CTRP1 2.4481 6.4676 1.7785 20.7771
BC-3C CTRP2 2.6728 4.7885 2.5436 17.3126
253J CTRP2 2.974 5.0352 2.8151 15.4161
SCaBER CTRP2 3.0937 5.479 2.8216 15.031
CAL-29 GDSC1; GDSC2; CTRP2 3.1628 5.3011 2.9501 14.3559
KU-19-19 GDSC1; GDSC2; CTRP2 3.6256 7.9632 1.8025 11.8378
VM-CUB-1 CTRP2 3.6733 7.0288 2.835 13.379
T24 GDSC1; GDSC2; CTRP2 3.7894 5.8763 3.4375 10.721
UM-UC-3 GDSC1; GDSC2; CTRP2; CTRP1 3.9146 6.0844 3.4889 10.1775
KMBC-2 CTRP2; CTRP1 3.9657 9.5501 1.9319 16.2771
HT-1197 GDSC1; GDSC2; CTRP2 4.3404 7.3853 3.3333 9.7229
J82 GDSC1; GDSC2; CTRP2 4.3659 8.6479 2.745 12.0796
SW1710 GDSC1; GDSC2; CTRP2 4.4038 6.9475 3.603 8.4718
253J-BV CTRP2 4.6691 8.0632 3.3105 9.0723
647V GDSC1; GDSC2; CTRP2 4.9271 9.1174 3.0155 9.7584
639V GDSC1; GDSC2; CTRP2 5.0944 8.327 2.8023 4.4929
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NT2-D1 GDSC1; GDSC2 0.019 4.1391 -0.5348 35.5967
PA-1 GDSC2 0.1235 3.6968 -0.2777 33.9811
SW954 GDSC1; GDSC2 0.131 3.0921 -0.1005 33.1444
KGN GDSC1; GDSC2 0.5991 3.4822 0.3051 28.8286
BPH-1 GDSC1; GDSC2 0.6099 4.5179 -0.0328 30.4303
PWR-1E GDSC1; GDSC2 0.9965 3.3897 0.7654 24.5471
TC-YIK GDSC1; GDSC2 1.1195 6.8318 -0.49 30.1228
CAL-39 GDSC1; GDSC2 1.1649 3.2079 0.998 22.5186
ACC-OV7 GDSC1; GDSC2 1.3604 4.5306 0.7624 22.9368
OVCA433 GDSC1; GDSC2 1.46 3.9752 1.0804 20.7364
SW962 GDSC1; GDSC2 1.7483 5.1037 0.9257 20.4053
NCC-IT GDSC1; GDSC2 1.7519 4.4853 1.1938 18.8522
JHOS-3 GDSC1; GDSC2 1.912 4.5286 1.3433 17.3311
OVCA420 GDSC1; GDSC2 2.2121 6.6019 0.685 19.9925
LB831-BLC GDSC1; GDSC2 2.2692 6.1708 0.9471 18.2874
HeLa GDSC1; GDSC2; CTRP2 2.4869 6.0555 1.9708 19.9511
SKG-IIIa GDSC1; GDSC2 2.5536 5.2777 1.6479 13.059
NEC8 GDSC1; GDSC2 2.618 4.2746 2.1806 9.5722
SiSo GDSC1; GDSC2 2.7526 6.6476 1.1637 15.3273
SKN GDSC1; GDSC2 2.7856 5.3458 1.8344 11.0996
OVMIU GDSC1; GDSC2 2.818 6.1569 1.4653 13.2768
JAR GDSC1; GDSC2 2.8582 4.1634 2.4719 6.9016
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 2.9507 5.2938 2.0117 9.4406
OV17R GDSC1; GDSC2 3.112 5.0135 2.2954 7.1368
Ca Ski GDSC1; GDSC2 3.1348 6.1438 1.7522 10.4859
DSH1 GDSC1; GDSC2 3.1489 5.1128 2.2785 7.1267
HEY GDSC1; GDSC2 3.1653 5.5433 2.0781 8.3412
MS751 GDSC1; GDSC2 3.3205 6.5597 1.7019 10.2441
C-33 A GDSC1; GDSC2 3.4304 7.9139 1.1157 13.5102
C-4-I GDSC1; GDSC2 3.511 7.0648 1.6056 10.2992
UWB1.289 GDSC1; GDSC2 3.5543 7.0853 1.6302 10.0265
HT-3 GDSC1; GDSC2 3.5616 8.9522 0.7039 15.5108
SiHa GDSC1; GDSC2 4.1297 7.4332 1.8944 6.9311
PEO1 GDSC1; GDSC2 4.1323 11.1867 0.0428 17.418
DoTc2 4510 GDSC1; GDSC2 4.3407 7.5448 1.9873 5.8989
JEG-3 GDSC1; GDSC2 4.367 8.2126 1.6833 7.6692
HEC-1 GDSC1; GDSC2 4.4683 8.92 1.4112 9.0597
ME-180 GDSC1; GDSC2 4.5671 14.1849 -1.1099 21.3746
SW756 GDSC1; GDSC2 5.0635 11.591 0.5335 12.6146
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924. Mol Cancer Ther. 2011 Jan;10(1):117-25.
2 Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro. Int J Pharm. 2015 Nov 10;495(1):588-598. doi: 10.1016/j.ijpharm.2015.09.042. Epub 2015 Sep 21.