Details of the Drug

General Information of Drug (ID: DMDUO8I)

Drug Name

JNJ-41443532

Synonyms

UNII-0OJB0LES1A; JNJ-41443532; 0OJB0LES1A; CHEMBL2204263; CFKBNYUHQSQBSX-UHFFFAOYSA-N; 1228650-83-6; SCHEMBL2485329; SCHEMBL2485331; SCHEMBL2545786; SCHEMBL13302364; BDBM50400695; DB12632; Benzamide, N-(2-((1-(trans-4-hydroxy-4-(5-thiazolyl)cyclohexyl)-3-azetidinyl)amino)-2-oxoethyl)-3-(trifluoromethyl)

Indication

Disease Entry	ICD 11	Status	REF
Type-2 diabetes	5A11	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C22H25F3N4O3S
Canonical SMILES: C1CC(CCC1N2CC(C2)NC(=O)CNC(=O)C3=CC(=CC=C3)C(F)(F)F)(C4=CN=CS4)O
InChI: 1S/C22H25F3N4O3S/c23-22(24,25)15-3-1-2-14(8-15)20(31)27-10-19(30)28-16-11-29(12-16)17-4-6-21(32,7-5-17)18-9-26-13-33-18/h1-3,8-9,13,16-17,32H,4-7,10-12H2,(H,27,31)(H,28,30)
InChIKey: CFKBNYUHQSQBSX-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 46208367
CAS Number: 1228650-83-6
UNII: 0OJB0LES1A
DrugBank ID: DB12632
TTD ID: D01UBY

References

1	ClinicalTrials.gov (NCT01230749) A Study of Multiple Oral Doses of JNJ-41443532 in Patients With Type 2 Diabetes Mellitus. U.S. National Institutes of Health.