Details of the Drug

General Information of Drug (ID: DMDYZRS)

Drug Name
BPS-804
Synonyms Anti-sclerostin antibody (osteoporosis/hypophophatasia), Novartis
Indication
Disease Entry ICD 11 Status REF
Metabolic bone disease FB8Y Phase 2 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D0XY4A

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Sclerostin (SOST) TTYRO4F SOST_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Metabolic bone disease
ICD Disease Classification FB8Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Sclerostin (SOST) DTT SOST 1.11E-01 0.9 2.87
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01806610) Study of Safety and Tolerability of BPS804 in Patients With Late-stage Chronic Kidney Disease. U.S. National Institutes of Health.
2 WO patent application no. 2010,1001,79, Self-forming gel system for sustained drug delivery.