Details of the Drug

General Information of Drug (ID: DME7V7X)

• Drug Name: OZ-439
• Synonyms: Oral quick release synthetic trioxolane (Plasmodium infections), MMV/UNMC/STPI/Monash University

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Phase 2	[1]

• Chemical Identifiers:
  Formula: C28H39NO5
  Canonical SMILES: C1CC2(CCC1C3=CC=C(C=C3)OCCN4CCOCC4)OC5(C6CC7CC(C6)CC5C7)OO2
  InChI: InChI=1S/C28H39NO5/c1-3-26(31-14-11-29-9-12-30-13-10-29)4-2-22(1)23-5-7-27(8-6-23)32-28(34-33-27)24-16-20-15-21(18-24)19-25(28)17-20/h1-4,20-21,23-25H,5-19H2
  InChIKey: XLCNVWUKICLURR-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 24999143
  CAS Number: 1029939-86-3
  UNII: RIK029813G
  DrugBank ID: DB11809
  TTD ID: D04TBC

References

• [1] ClinicalTrials.gov (NCT02083380) Phase IIb Study to Investigate the Efficacy of OZ439 & Piperaquine Phosphate Co-administered to Adults & Children With Uncomplicated Plasmodium Falciparum.. U.S. National Institutes of Health.