Details of the Drug

General Information of Drug (ID: DMEJYV4)

Drug Name
(S)-4-(Ethylsulfonyl)benzoylalanine
Synonyms S-ESBA
Indication
Disease Entry ICD 11 Status REF
Cognitive impairment 6D71 Preclinical [1]
Schizophrenia 6A20 Preclinical [1]
Drug Type
Small molecular drug
Cross-matching ID
TTD ID
DVQ37G
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Kynurenine oxoglutarate transaminase II (AADAT) TTT3IXG AADAT_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond. Nat Rev Drug Discov. 2019 May;18(5):379-401.
2 Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum. Neuroscience. 2009 Mar 3;159(1):196-203.