Details of the Drug

General Information of Drug (ID: DMEK4TJ)

Drug Name
PI-103
Synonyms
PI-103; 371935-74-9; PI103; 3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol; UNII-YQX02F616F; PI 103; PIK-103; Phenol, 3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]-; YQX02F616F; CHEBI:90524; AK163162; 3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol; 3-(4-Morpholin-4-Ylpyrido[3',2':4,5]furo[3,2-D]pyrimidin-2-Yl)phenol; Phenol, 3-(4-(4-morpholinyl)pyrido(3',2':4,5)furo(3,2-d)pyrimidin-2-yl)-; 3-(4-(4-Morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol
Indication
Disease Entry ICD 11 Status REF
Haematological malignancy 2B33.Y Investigative [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 348.4
Logarithm of the Partition Coefficient (xlogp) 2.7
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C19H16N4O3
IUPAC Name
3-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)phenol
Canonical SMILES
C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O
InChI
InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2
InChIKey
TUVCWJQQGGETHL-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
9884685
ChEBI ID
CHEBI:90524
CAS Number
371935-74-9
UNII
YQX02F616F
DrugBank ID
DB17046
TTD ID
D0W8XH
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [3]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [4]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [3]
Carbonic anhydrase 9 (CA9) OTNA51XT CAH9_HUMAN Post-Translational Modifications [5]
Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1) OT4Y9NQI MP2K1_HUMAN Post-Translational Modifications [6]
Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2) OTUE7Z91 MP2K2_HUMAN Post-Translational Modifications [6]
Hypoxia-inducible factor 1-alpha (HIF1A) OTADSC03 HIF1A_HUMAN Post-Translational Modifications [5]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Gene/Protein Processing [3]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Post-Translational Modifications [6]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Post-Translational Modifications [6]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Haematological malignancy
ICD Disease Classification 2B33.Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase gamma (PIK3CG) DTT PIK3CG 1.98E-01 -0.05 -0.55
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 -3.7172 4.1298 -4.5876 68.6612
ES1 GDSC1 -3.5856 0.221 -3.6476 77.7712
EW-18 GDSC1 -3.2132 -0.3762 -3.229 77.6109
ES5 GDSC1 -2.9466 -0.3227 -2.9588 75.6326
ES7 GDSC1 -2.396 -0.3383 -2.4001 70.9109
EW-11 GDSC1 -2.1675 0.6775 -2.2034 67.0418
EW-13 GDSC1 -2.0026 10.8837 -5.4566 55.5552
EW-16 GDSC1 -1.5048 2.3003 -1.7023 58.7581
SK-N-MC CTRP2 -1.3899 2.6027 -1.4836 44.0853
MHH-ES-1 GDSC1; CTRP2 -1.3406 0.8364 -1.3432 43.5648
ES8 GDSC1 -1.2676 1.9822 -1.392 56.7949
TC-71 GDSC1 -0.9136 0.2884 -0.914 53.3669
EW-1 GDSC1 -0.9042 0.9991 -0.9168 53.1898
NOS-1 [Human HNSCC] GDSC1 -0.5423 5.1819 -1.5065 49.1804
ES4 GDSC1 -0.537 3.9197 -1.0588 48.9908
SK-ES-1 GDSC1; CTRP2 -0.5335 2.6699 -0.5892 38.3606
HuO9 GDSC1 -0.4625 5.7185 -1.6304 48.6143
G-292 clone A141B1 GDSC1; CTRP2 -0.3695 9.7058 -2.503 41.3627
CADO-ES1 GDSC1 -0.3292 3.3368 -0.6605 46.7254
EW-7 GDSC1 -0.2783 1.0511 -0.2813 45.4441
EW-3 GDSC1 -0.2064 3.9577 -0.7112 45.7209
CAL-78 GDSC1; CTRP2 0.2413 7.7615 -1.0736 36.6573
SaOS-2 GDSC1; CTRP2 0.3107 5.2795 -0.156 34.0392
H-EMC-SS GDSC1 0.7489 7.8894 -1.3312 40.5622
ES6 GDSC1 0.7522 6.9034 -0.8762 39.4324
SK-PN-DW GDSC1 0.8716 3.8014 0.5112 33.1964
A-673 GDSC1; CTRP2 0.9186 4.8517 0.6194 29.541
MG-63 GDSC1; CTRP2 1.0569 10.1585 -1.223 34.3039
TC71 CTRP2 1.1833 2.5082 1.1818 26.7789
Hs 888.T CTRP2 1.6908 8.3804 0.2039 28.4849
HuO-3N1 GDSC1 1.7596 17.6798 -5.1762 41.9798
SJSA-1 GDSC1; CTRP2 2.2385 7.5857 1.11 23.8269
Hs 822.T CTRP2 2.8142 11.4454 -0.0759 29.565
CHSA0011 GDSC1 3.0951 10.4911 -0.4312 26.8048
CHSA8926 GDSC1 3.6994 10.471 0.0806 22.1284
HOS GDSC1; CTRP2 4.3422 7.0189 3.5091 9.0017
U2OS GDSC1; CTRP2; CTRP1 4.6986 16.2475 -0.7408 23.83
CAL-72 GDSC1 5.3963 6.8177 2.8941 0.3381
EW-24 GDSC1 5.4915 6.9004 2.9003 0.2819
CHSA0108 GDSC1 5.617 15.2775 -0.8415 20.6764
NY GDSC1 6.5881 8.6023 2.7073 0.3324
SW1353 CTRP2 11.39 22.0428 1.2147 7.5432
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 209 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -0.7309 6.1618 -1.5565 41.3107
MEC1 CTRP2 -0.0984 4.5317 -0.4131 36.2445
JM1 GDSC1; CTRP2 0.7076 10.2677 -1.6285 36.2734
YT GDSC1 -7.1944 2.1852 -7.8607 80.9342
PL-21 GDSC1 -6.1319 3.3449 -6.9954 76.7985
SU-DHL-16 GDSC1 -6.0402 -4.6129 -6.0402 99.105
HAL-01 GDSC1 -5.9413 -1.2787 -5.9938 88.8321
MY-M12 GDSC1 -5.7681 3.9524 -6.7704 74.869
QIMR-WIL GDSC1 -5.6911 3.8264 -6.6497 74.9423
Ri-1 CTRP2 -5.6087 1.7072 -5.8576 67.2898
EB2 GDSC1 -5.4345 1.0851 -5.7264 80.7735
Karpas-231 GDSC1 -5.3268 -3.1042 -5.3272 94.7992
NKM-1 GDSC1 -5.3047 3.3054 -6.0819 75.1017
P30/OHK GDSC1 -5.2171 1.6976 -5.605 78.6522
KMS-26 CTRP2 -5.0485 -1.7894 -5.0514 67.8387
CESS GDSC1 -4.8682 -0.8392 -4.9091 85.7289
HH [Human lymphoma] GDSC1 -4.7728 8.393 -7.2622 66.048
SU-DHL-6 GDSC1; CTRP2 -4.7483 -1.337 -4.7534 65.8512
ARH-77 GDSC1 -4.6394 3.5736 -5.4299 72.7876
SU-DHL-10 GDSC1 -4.5899 -3.7394 -4.5899 96.2974
ML-2 GDSC1 -4.4404 -1.1789 -4.4559 85.9205
MOLM-13 GDSC1 -4.3834 -0.33 -4.4382 82.6756
P32/ISH GDSC1 -4.3331 0.0294 -4.414 81.2898
MN-60 GDSC1 -4.2624 4.7847 -5.388 69.3996
LC4-1 GDSC1 -4.2452 2.2607 -4.668 74.5068
SU-DHL-5 GDSC1; CTRP1 -4.1775 -3.1446 -4.1775 93.7625
MLMA GDSC1 -4.1066 -0.8824 -4.1247 83.7356
WIL2 NS GDSC1 -3.8352 2.5197 -4.2804 72.4239
NCI-H929 CTRP2 -3.8018 -1.4759 -3.8022 59.902
BC-1 GDSC1 -3.7763 3.0475 -4.3456 71.0131
Farage GDSC1 -3.7607 -1.1166 -3.7672 83.1036
Pfeiffer CTRP2 -3.6816 -0.3061 -3.691 58.9709
GR-ST GDSC1 -3.6789 1.5134 -3.9082 74.3507
NU-DUL-1 GDSC1; CTRP2; CTRP1 -3.6428 -2.7015 -3.6428 58.8668
RPMI-8402 GDSC1; CTRP2 -3.6165 -0.983 -3.618 58.6524
CTB-1 GDSC1 -3.5709 7.6601 -5.6969 63.315
GA-10 CTRP2 -3.469 0.7976 -3.513 57.3791
TK [Human B-cell lymphoma] GDSC1 -3.3471 6.2233 -4.9026 64.1404
MOLP-8 GDSC1; CTRP2 -3.2354 0.3464 -3.2536 56.03
Ramos.2G6.4C10 GDSC1 -3.2232 -1.5019 -3.2236 80.765
KMS-34 CTRP2 -3.1103 -1.5638 -3.1103 55.3254
MHH-PREB-1 GDSC1 -2.8985 4.5912 -3.843 64.4866
Hs 611.T CTRP2 -2.8873 5.3241 -3.6583 52.9339
Daudi GDSC1; CTRP2 -2.8268 0.314 -2.8371 53.4044
NALM-6 GDSC1; CTRP2 -2.8028 -0.0823 -2.8066 53.2652
VAL GDSC1 -2.774 6.1336 -4.2547 61.9473
WSU-DLCL2 GDSC1; CTRP2; CTRP1 -2.7445 -0.2154 -2.7468 52.8847
KCL-22 GDSC1; CTRP2 -2.7003 0.0241 -2.7045 52.5868
Karpas-422 GDSC1; CTRP2 -2.6962 4.2234 -3.1704 52.1386
EB1 CTRP2 -2.6809 5.0673 -3.3631 51.9458
KG-1 GDSC1 -2.6289 4.4815 -3.5142 63.3486
MOLT-4 GDSC1 -2.5924 0.8939 -2.6654 70.0081
LP-1 GDSC1; CTRP2; CTRP1 -2.5874 2.4299 -2.7329 51.716
EoL-1 GDSC1; CTRP2 -2.5652 0.9113 -2.5883 51.6719
ALL-PO GDSC1 -2.508 1.5631 -2.6582 67.9041
697 GDSC1; CTRP2 -2.4451 1.457 -2.4922 50.8768
CCRF-CEM GDSC1 -2.4338 0.159 -2.4511 70.3741
JSC-1 GDSC1 -2.4249 5.6862 -3.7135 60.8467
BL-70 CTRP2; CTRP1 -2.4115 -0.8692 -2.4115 50.6786
MV4-11 GDSC1; CTRP2 -2.3978 0.8425 -2.4146 50.5804
VL51 GDSC1 -2.3844 10.8614 -5.8325 56.9213
HC-1 GDSC1 -2.3767 8.4526 -4.7695 58.2646
OCI-AML-3 GDSC1; CTRP2; CTRP1 -2.3542 2.038 -2.4431 50.2846
Sc-1 GDSC1 -2.3509 4.672 -3.2754 61.6532
Karpas-45 GDSC1 -2.3236 2.397 -2.6093 64.9896
KMS-12-BM GDSC1; CTRP2 -2.2929 2.3622 -2.4123 49.8964
SU-DHL-4 GDSC1; CTRP2; CTRP1 -2.2619 0.3634 -2.2665 49.6854
KMS-11 GDSC1; CTRP2; CTRP1 -2.1859 7.1765 -3.4728 49.4187
KE-37 GDSC1 -2.1746 1.5364 -2.2978 65.5172
Hs 445 GDSC1 -2.11 12.249 -6.1883 55.4191
MOLM-16 CTRP2; CTRP1 -2.0392 1.3171 -2.0655 48.229
SUP-M2 GDSC1; CTRP2 -2.0052 1.5912 -2.0446 48.018
GDM-1 GDSC1; CTRP2; CTRP1 -1.9328 0.4272 -1.9356 47.5001
Kasumi-1 GDSC1; CTRP2 -1.8474 1.6767 -1.8863 46.9843
MC116 GDSC1; CTRP2; CTRP1 -1.8016 -0.9482 -1.8016 46.6231
NOMO-1 GDSC1; CTRP2; CTRP1 -1.7522 3.0793 -1.9303 46.5318
SUP-T11 CTRP2 -1.7375 2.8344 -1.8801 46.3985
Namalwa GDSC1; CTRP2 -1.7132 2.2643 -1.7906 46.1601
KOPN-8 GDSC1 -1.6723 4.5735 -2.5064 57.7453
CA46 GDSC1; CTRP2 -1.577 4.4447 -2.0028 45.724
Ki-JK CTRP2 -1.5402 4.7075 -2.0259 45.5703
PL21 CTRP2; CTRP1 -1.5258 2.2515 -1.5929 44.9234
Loucy GDSC1 -1.5079 1.2777 -1.5614 59.8559
MOLT-3 CTRP2 -1.5017 3.0711 -1.661 44.9177
RS4;11 GDSC1; CTRP2 -1.4782 4.848 -1.9935 45.2372
SIG-M5 GDSC1; CTRP2 -1.4687 -0.9443 -1.4687 44.4092
BCP-1 CTRP2 -1.4543 2.5114 -1.5421 44.4934
Kasumi-2 CTRP2 -1.3453 5.4641 -2.0151 44.6428
OCI-Ly19 GDSC1; CTRP2 -1.2564 4.5635 -1.6816 43.7885
RPMI-8226 GDSC1; CTRP2; CTRP1 -1.2016 2.4037 -1.2662 42.7934
OPM-2 GDSC1; CTRP2 -1.1239 2.9757 -1.2451 42.4097
EJM GDSC1; CTRP2; CTRP1 -1.1094 4.8011 -1.5795 42.9648
ATN-1 GDSC1 -1.1073 2.9319 -1.406 54.6031
THP-1 GDSC1; CTRP2; CTRP1 -1.0783 3.2073 -1.2277 42.1739
PF-382 GDSC1; CTRP2 -1.069 5.4783 -1.7177 43.0044
BALL-1 GDSC1 -1.0634 3.2868 -1.4483 54.0099
NU-DHL-1 CTRP2 -0.9051 4.8112 -1.3592 41.6856
L-363 GDSC1; CTRP2 -0.8463 3.1741 -0.9754 40.6177
Mono-Mac-6 GDSC1; CTRP2 -0.7897 7.2658 -1.9954 42.2426
Reh GDSC1; CTRP2 -0.7529 1.9746 -0.7731 39.7114
MOLT-16 GDSC1; CTRP2 -0.6981 2.5111 -0.7484 39.4346
HT GDSC1; CTRP2; CTRP1 -0.6397 4.9958 -1.1168 40.0887
HL-60 GDSC1; CTRP2 -0.614 4.5935 -0.9889 39.7016
KMS-20 CTRP2 -0.5907 2.4887 -0.6347 38.7053
RCH-ACV CTRP2 -0.5636 4.9902 -1.0324 39.5965
Ku812 GDSC1; CTRP2; CTRP1 -0.5631 3.1361 -0.6689 38.6989
Granta-519 GDSC1; CTRP2 -0.5144 7.7508 -1.8774 40.9841
OCI-Ly10 CTRP2; CTRP1 -0.5134 5.6012 -1.1473 39.6443
JJN-3 GDSC1; CTRP2 -0.4407 5.1103 -0.9299 38.8745
MHH-CALL-4 CTRP2 -0.4287 4.0299 -0.6663 38.1759
KE-97 CTRP2; CTRP1 -0.3989 3.7524 -0.5837 37.8394
RL GDSC1; CTRP2 -0.3723 3.3013 -0.4869 37.467
A4/Fukuda GDSC1; CTRP2 -0.2891 5.2968 -0.8154 38.0133
MEG-01 GDSC1 -0.2778 5.2734 -1.2591 46.9859
ST486 GDSC1; CTRP2 -0.2243 4.9893 -0.662 37.3833
BV-173 GDSC1; CTRP2 -0.1745 4.5517 -0.5006 36.7685
SUP-HD1 GDSC1; CTRP2 -0.1203 5.0352 -0.5605 36.7276
HEL GDSC1; CTRP2 -0.0319 2.951 -0.1496 30.4393
P3HR-1 CTRP2; CTRP1 -0.0239 4.1702 -0.2554 35.5201
KMS-18 CTRP2 0.0277 2.6598 -0.0036 34.561
P12-Ichikawa GDSC1 0.0994 5.2702 -0.8567 43.608
RPMI-6666 GDSC1; CTRP2 0.1018 4.772 -0.2516 35.0579
F-36P CTRP2 0.1227 3.502 0.0141 34.1782
SUP-T1 GDSC1; CTRP2 0.2347 8.3094 -1.2957 37.1648
OCI-AML-5 GDSC1; CTRP2 0.2378 4.3474 -0.0075 33.8464
CTV-1 GDSC1 0.2567 7.9907 -1.8687 44.2366
Mono-Mac-1 CTRP2 0.2686 7.1863 -0.8273 35.985
OCI-Ly3 CTRP2 0.3008 4.6645 -0.0091 33.6324
A3/Kawakami GDSC1; CTRP2 0.3284 6.406 -0.4863 34.9042
SR GDSC1; CTRP2 0.4986 3.6242 0.3985 31.6591
ROS-50 GDSC1 0.5213 9.0752 -2.1096 43.153
SKM-1 CTRP2; CTRP1 0.6151 2.217 0.6124 30.5613
U-937 CTRP2; CTRP1 0.7044 3.6106 0.6194 30.2426
ALL-SIL GDSC1; CTRP2 0.7533 5.35 0.3072 31.1073
TUR GDSC1 0.7737 4.7637 0.0588 36.0644
NB4 GDSC1; CTRP2 0.815 3.6273 0.7349 29.491
DND-41 GDSC1; CTRP2 0.8391 5.9741 0.2112 31.1289
KMS-27 CTRP2 0.8636 8.1219 -0.5555 33.2745
JVM-2 GDSC1; CTRP2 0.9421 12.9612 -3.1387 35.186
SK-MM-2 GDSC1; CTRP2 0.9651 5.12 0.6016 29.4496
NCO2 CTRP2 0.9899 9.5323 -1.0168 34.0315
RPMI-8866 GDSC1 1.0477 9.0905 -1.6057 39.613
U266B1 GDSC1; CTRP2 1.0662 8.958 -0.6909 32.979
MM1.S CTRP2 1.1377 11.1749 -1.5984 34.8803
DB GDSC1; CTRP2 1.1416 5.8868 0.5683 28.9943
SET-2 CTRP2 1.1942 3.1843 1.1729 26.7725
L-428 GDSC1; CTRP2 1.1946 7.3066 0.1186 30.2716
SCC-3 GDSC1 1.2091 5.7225 0.1152 33.1297
HuT 78 CTRP2 1.2789 7.7064 0.0506 30.2156
Karpas-299 GDSC1; CTRP2 1.3016 6.7618 0.4389 28.9165
SU-DHL-8 GDSC1; CTRP2 1.3071 5.6606 0.8195 27.6236
M-07e CTRP2 1.3113 13.9166 -2.7046 36.4516
KM-H2 GDSC1; CTRP2 1.3122 12.1076 -1.8537 34.8901
L-540 GDSC1; CTRP2 1.3429 7.3667 0.2531 29.3863
MOLM-6 CTRP2 1.349 6.8076 0.4729 28.6577
TALL-1 [Human adult T-ALL] CTRP2 1.359 7.1669 0.3478 29.0337
WSU-NHL GDSC1 1.3661 9.7773 -1.6333 38.1596
JURL-MK1 GDSC1 1.4235 5.0235 0.6383 29.1495
U-698-M GDSC1 1.4298 7.1205 -0.3007 33.7062
EM-2 GDSC1 1.5062 13.5888 -3.3732 40.7379
CMK CTRP2 1.5148 3.4175 1.4908 24.6496
AML-193 CTRP2 1.6142 9.1338 -0.2008 29.9439
Jiyoye GDSC1 1.6374 7.2065 -0.1386 31.9379
HPB-ALL CTRP2 1.7351 6.1734 1.1167 25.2733
CML-T1 CTRP2 1.891 6.5568 1.1477 24.6974
AMO1 GDSC1; CTRP2; CTRP1 1.9002 7.0027 0.9882 25.2358
BE-13 GDSC1 2.0421 9.1168 -0.6812 32.1893
SUP-B15 GDSC1; CTRP2 2.1431 11.5292 -0.7655 30.0045
K-562 GDSC1; CTRP2 2.1672 6.0038 1.6429 22.0924
SEM CTRP2 2.1721 9.0577 0.4028 26.4527
OCI-M1 GDSC1; CTRP2 2.1727 3.5228 2.164 20.2235
OCI-AML-2 GDSC1; CTRP2 2.2102 8.6308 0.6312 25.5824
DEL GDSC1; CTRP2 2.2743 7.6546 1.1185 23.6951
MOLP-2 CTRP2 2.2894 8.7422 0.6628 25.2534
LAMA-84 GDSC1; CTRP2 2.3185 11.1478 -0.4144 28.5579
L-1236 GDSC1 2.3636 11.0299 -1.3364 33.0596
JeKo-1 CTRP2 2.4501 12.9316 -1.1379 30.1409
HuNS1 CTRP2 2.5454 9.1692 0.7294 24.3216
KY821 GDSC1 2.6446 7.2338 0.7965 22.1356
HD-MY-Z CTRP2 2.7965 7.612 1.6791 20.1841
MHH-CALL-3 CTRP2 2.8333 9.257 0.9764 22.6854
DG-75 GDSC1 2.8895 8.5911 0.3403 23.7988
HEL 92.1.7 CTRP2 2.9116 5.5351 2.6058 16.3621
KYO-1 CTRP2 3.1552 6.3066 2.5953 15.702
EHEB CTRP2 3.1953 12.9364 -0.4386 26.3637
P31/FUJ GDSC1; CTRP2 3.248 7.2444 2.3041 16.5756
MOLT-13 GDSC1; CTRP2 3.36 10.2243 1.0325 21.1441
ME1 GDSC1 3.4125 17.1474 -3.4926 34.7897
KO52 CTRP2 3.5549 9.6975 1.4719 19.0356
MOTN-1 CTRP2 3.6735 14.8125 -0.9253 26.5879
SU-DHL-1 GDSC1; CTRP2 3.7339 8.9474 2.0032 16.5419
JVM-3 GDSC1; CTRP2 4.0938 8.7334 2.4491 13.9075
TF-1 CTRP2 4.1588 7.0864 3.2973 10.306
KMOE-2 GDSC1 4.5099 10.2543 0.815 15.2591
Peer CTRP2 4.5347 10.5741 1.9459 14.9527
HDLM-2 GDSC1; CTRP2 4.5418 13.4146 0.538 20.1712
RC-K8 GDSC1 4.6362 7.7574 2.1089 6.0259
BC-3 GDSC1 4.6484 7.9932 2.0058 6.7356
H9 GDSC1 4.937 18.6521 -3.0176 29.6009
Ci-1 CTRP2 5.3974 7.445 4.2442 3.7021
BL-41 GDSC1; CTRP2 5.5208 24.8813 -4.3682 30.1305
MJ CTRP2 5.8577 7.8913 4.3627 2.4809
Raji GDSC1; CTRP2 6.7626 8.0419 4.786 0.2599
Karpas-620 GDSC1; CTRP2 6.774 8.4351 4.6391 0.5977
KMM-1 CTRP2 6.8144 12.7883 2.66 7.9324
REC-1 CTRP2 7.1469 9.6712 4.3114 1.2981
Toledo CTRP2 7.3125 26.1106 -3.5444 25.6737
ME1 CTRP2 7.8592 15.7624 1.9444 9.1819
Jurkat CTRP2 7.9705 22.1948 -1.9053 17.5779
⏷ Show the Full List of 209 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 2.0101 5.6811 1.5785 22.7937
TE8 CTRP2 3.4145 9.5227 1.4208 19.5721
TE-15 GDSC1 -2.1713 7.6073 -4.2003 57.9813
KYSE-140 GDSC1; CTRP2; CTRP1 0.0254 4.2376 -0.2154 35.225
KYSE-270 GDSC1 0.0844 16.7348 -6.2232 47.6535
TE-14 CTRP2 0.7092 6.1375 0.0167 32.1608
OE21 GDSC1; CTRP2 0.7297 4.3224 0.531 30.4537
KYSE-520 GDSC1; CTRP2 1.1639 5.9887 0.5594 28.953
T.T GDSC1 1.9387 6.6884 0.3995 27.7596
KYSE-450 GDSC1; CTRP2; CTRP1 2.169 4.6273 2.0302 20.6943
OE33 GDSC1; CTRP2 2.4838 12.2268 -0.7671 29.0922
KYSE-30 CTRP2 2.7629 7.0732 1.8722 19.5429
TE-5 GDSC1; CTRP2 2.9537 4.6629 2.8725 15.2778
KYSE-150 GDSC1; CTRP2 3.0032 8.8172 1.3486 20.882
TE-6 GDSC1; CTRP2 3.2031 8.3076 1.7825 18.7203
KYSE-510 GDSC1; CTRP2 3.208 11.2066 0.4144 23.6731
COLO 680N GDSC1; CTRP2 3.2869 9.2403 1.431 19.8505
TE-10 GDSC1; CTRP2 3.2987 11.262 0.4733 23.2512
TE-4 GDSC1; CTRP2 3.5011 6.9349 2.6994 14.3621
TE-11 GDSC1; CTRP2 3.7747 5.7689 3.4618 10.6704
EC-GI-10 GDSC1; CTRP2 3.8453 6.3584 3.3029 11.0866
KYSE-410 GDSC1; CTRP2; CTRP1 4.7919 7.0817 3.9061 6.33
TE-8 GDSC1 5.3886 20.6002 -3.6361 29.96
OE19 GDSC1; CTRP2 6.6978 7.7847 4.8545 0.1585
TE-9 GDSC1; CTRP2 7.534 8.8944 4.7731 0.0953
KYSE-70 GDSC1; CTRP2 7.7885 15.1971 2.1669 8.4477
KYSE-180 GDSC1; CTRP2 7.8739 9.7074 4.6141 0.2232
TE-1 GDSC1; CTRP2 8.0754 21.4132 -0.6458 17.5048
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.1504 7.6561 4.6527 1.029
PaTu 8902 GDSC1; CTRP2; CTRP1 -1.3814 3.911 -1.675 44.3612
MZ-PC-1 GDSC1 -1.351 3.3422 -1.7771 56.4567
DAN-G GDSC1; CTRP2 -0.0649 4.9412 -0.4756 36.2939
Panc 10.05 GDSC1; CTRP2; CTRP1 0.1538 6.6187 -0.7483 36.2011
Panc 08.13 GDSC1; CTRP2 0.3894 4.7467 0.0679 33.0892
PSN1 GDSC1; CTRP2 1.0503 9.497 -0.9392 33.6538
HuP-T3 GDSC1; CTRP2 1.7868 11.8366 -1.2592 32.2341
CFPAC-1 GDSC1; CTRP2; CTRP1 1.8931 7.5134 0.777 25.993
Capan-2 GDSC1; CTRP2; CTRP1 2.1605 9.4855 0.1984 27.1457
Panc 03.27 GDSC1; CTRP2; CTRP1 2.3973 6.5477 1.6938 21.2368
KP-4 GDSC1; CTRP2 2.4793 9.5827 0.4738 25.3689
PaTu 8988t GDSC1; CTRP2 2.5438 9.3034 0.6665 24.543
QGP-1 GDSC1; CTRP2; CTRP1 2.5608 10.8985 -0.0602 26.858
SW1990 GDSC1; CTRP2 2.846 7.8308 1.6346 20.2197
KP-3 GDSC1; CTRP1 2.942 7.0748 2.0591 27.678
Panc 04.03 GDSC1; CTRP2 3.2202 8.7008 1.618 19.3083
PANC-1 CTRP2 3.2479 9.6353 1.2061 20.7876
MIA PaCa-2 GDSC1; CTRP2 3.9789 7.2511 3.0424 11.7776
PL4 GDSC1 4.8609 13.439 -0.4928 21.2226
Capan-1 GDSC1; CTRP2 5.0917 6.3495 4.5386 3.05
HuP-T4 GDSC1; CTRP2; CTRP1 5.2124 8.9731 3.3301 7.8775
PaTu 8988s CTRP2 5.225 7.7736 3.9403 5.2949
KP-2 GDSC1; CTRP2 5.5123 8.7441 3.6878 5.8242
SU.86.86 GDSC1; CTRP2 5.59 10.0139 3.1166 8.0684
Panc 02.03 GDSC1; CTRP2 6.3964 8.788 4.2859 2.0972
SNU-410 CTRP2 6.4375 11.3488 3.0933 6.7634
HPAC GDSC1; CTRP2; CTRP1 6.5616 9.2409 4.178 2.3122
SUIT-2 GDSC1; CTRP2; CTRP1 6.5787 7.9842 4.7295 0.4729
YAPC GDSC1; CTRP2 7.0219 8.3597 4.7721 0.2012
Hs 766T GDSC1; CTRP2 7.0645 8.5689 4.7125 0.2935
PK-45H CTRP2 7.1666 9.4332 4.4198 0.9587
Panc 05.04 CTRP2 7.1983 8.8292 4.6699 0.3275
AsPC-1 GDSC1; CTRP2 7.2814 13.0008 2.8757 6.4211
SNU-213 CTRP2 7.3513 8.9014 4.7037 0.2201
L3.3 CTRP2 7.4228 8.868 4.7423 0.1486
BxPC-3 GDSC1; CTRP2 7.4425 9.6654 4.454 0.7022
HPAF-II GDSC1; CTRP2 7.4918 9.0305 4.7107 0.1756
TCC-Pan2 CTRP2 7.5047 9.0492 4.7089 0.1752
PK-59 CTRP2 7.7227 16.3248 1.5813 10.7152
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 2.7778 19.1387 -3.8727 34.7026
WM35 GDSC1 -4.1587 2.4158 -4.6087 73.8379
CHL-1 GDSC1 -3.8343 6.8927 -5.677 65.028
WM115 GDSC1; CTRP2 -2.4835 5.4601 -3.2559 50.9004
WM1552C GDSC1 -2.296 3.2071 -2.7722 63.4227
MZ-MEL-2 GDSC1 -2.1783 4.3879 -2.994 61.0505
RPMI-7951 GDSC1 -1.7724 6.1183 -3.1792 57.0904
COLO 792 GDSC1; CTRP2 -1.2192 4.9257 -1.731 43.6925
Hs 688(A).T CTRP2 -1.2059 13.8463 -5.1715 46.3397
WM88 CTRP2 -0.9607 4.1843 -1.2745 41.7604
A-388 GDSC1 -0.8356 6.6186 -2.3903 51.2689
Hs 934.T CTRP2 -0.7609 13.2485 -4.452 44.5654
G-mel GDSC1 -0.1068 10.2531 -3.2786 47.3141
COLO 679 GDSC1 -0.0113 6.3212 -1.4047 45.2638
IST-MEL1 GDSC1 0.2074 19.5915 -7.5148 47.6298
SK-MEL-5 GDSC1; CTRP2; CTRP1 0.3537 6.5256 -0.4997 34.8514
Hs 852.T CTRP2; CTRP1 0.4778 9.5821 -1.5679 36.8979
WM266-4 CTRP2 0.7636 6.371 -0.0029 32.0383
WM793 GDSC1; CTRP2 1.3492 6.4846 0.5905 28.2673
Hs 294T CTRP2 1.3718 6.8143 0.4949 28.5145
COLO 829 GDSC1; CTRP2 1.662 8.7731 0.0055 29.1859
A-431 GDSC1 1.6869 5.6879 0.6169 27.8289
IGR-39 CTRP2 1.8111 7.8045 0.5713 26.9328
A-375 GDSC1; CTRP2; CTRP1 1.9217 5.4331 1.558 23.1346
IPC-298 GDSC1; CTRP2 2.0045 7.4458 0.922 25.1641
COLO 800 GDSC1; CTRP2 2.016 7.1429 1.0561 24.6574
Hs 895.T CTRP2 2.0895 9.3827 0.1732 27.4255
Hs 940.T GDSC1; CTRP2 2.094 9.4063 0.1671 31.143
451Lu GDSC1 2.3021 9.2393 -0.5042 30.3437
Mel JuSo GDSC1; CTRP2 2.3071 6.8732 1.4716 22.3158
LOX-IMVI GDSC1; CTRP2 2.4339 8.1762 1.0602 23.4595
Hs 944.T CTRP2; CTRP1 2.5327 10.4902 0.1046 26.4217
SK-MEL-3 GDSC1; CTRP2 2.5638 10.7578 0.0091 26.6367
SK-MEL-24 GDSC1; CTRP2 2.6247 9.7318 0.5495 24.7239
GAK GDSC1 2.649 6.8538 0.9879 20.8833
HMV-II GDSC1 2.6551 12.1104 -1.6181 32.7872
UACC-257 GDSC1; CTRP2 2.8247 9.3721 0.9146 22.9284
RVH-421 GDSC1; CTRP2 2.8357 11.0115 0.1524 25.4722
SH-4 GDSC1 3.0103 13.2778 -1.8957 32.3141
A2058 GDSC1; CTRP2 3.1685 6.8221 2.4015 16.4096
CP50-MEL-B GDSC1 3.1777 7.2038 1.2816 16.7006
WM983B CTRP2 3.1805 11.1195 0.4304 23.6885
DJM-1 GDSC1 3.1806 7.2414 1.2654 16.8034
MeWo GDSC1; CTRP2 3.237 12.6027 -0.2369 25.6658
COLO 741 CTRP2; CTRP1 3.4246 20.6091 -4.0241 33.5521
Hs 936.T CTRP2; CTRP1 3.4727 12.3665 0.0973 24.0588
UACC-62 GDSC1; CTRP2 3.5135 6.2947 2.9804 13.2356
WT2-iPS GDSC1; CTRP2 3.6495 11.7357 0.5698 22.0754
CP66-MEL GDSC1 3.6851 10.8303 -0.1105 23.1486
IGR-1 GDSC1; CTRP2 3.7642 7.2718 2.818 13.2143
SK-MEL-30 GDSC1; CTRP2 3.8682 10.5989 1.329 18.8323
HMCB CTRP2 3.9311 9.8852 1.7362 17.1259
IGR-37 GDSC1; CTRP2 3.9889 7.592 2.8937 12.3529
COLO 783 GDSC1 4.2937 11.1735 0.1987 19.5151
Hs 839.T CTRP2 4.3108 13.8203 0.1339 22.0154
MZ-MEL-7 GDSC1 4.4102 10.4372 0.6511 16.5664
HT-144 GDSC1; CTRP2 4.6561 6.4933 4.0633 5.9932
G-361 GDSC1; CTRP2; CTRP1 4.8595 9.5785 2.7268 11.0954
SK-MEL-1 GDSC1; CTRP2; CTRP1 5.006 11.8629 1.7117 14.8938
VMRC-MELG GDSC1 5.0367 8.4481 2.037 5.6244
LB2518-MEL GDSC1 5.1255 6.1175 3.0388 0.111
Mel Ho GDSC1; CTRP2 5.5757 11.5884 2.3198 11.3712
A101D GDSC1; CTRP2 6.0414 8.6821 4.108 3.2431
Hs 938.T GDSC1 6.0705 13.8607 0.1573 14.8178
WM278 GDSC1 6.1067 7.9108 2.7728 0.3539
M14 GDSC1 6.115 7.3788 2.9551 0.0591
SK-MEL-28 GDSC1; CTRP2; CTRP1 6.1268 16.4558 0.3313 17.7344
SK-MEL-2 GDSC1; CTRP2 6.2072 7.6347 4.6927 0.8423
Malme-3M CTRP2 6.4298 15.1076 1.237 14.0344
CJM [Human melanoma] CTRP2 6.4421 14.5043 1.5451 12.8693
K029AX CTRP2 6.5473 8.3945 4.5452 1.0362
WM1799 CTRP2 6.6703 27.8282 -4.9067 29.0995
LB373-MEL-D GDSC1 7.001 16.9866 -0.7133 16.8255
MDA-MB-435S CTRP2 7.4505 13.6967 2.6568 7.0407
MMAc-SF GDSC1 7.5044 20.6719 -2.1361 21.1282
SK-MEL-31 CTRP2 7.7944 14.4318 2.5335 7.0558
EquiPSC Line K2 GDSC1 3.8749 6.6354 2.1262 7.9573
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACM5.1 C GDSC1 -4.4397 2.3282 -4.8946 74.9633
KYSE-50 GDSC1 -3.8598 4.4121 -4.8307 68.684
KYAE-1 GDSC1 -3.4756 1.9626 -3.7706 72.2985
OACP4 C GDSC1 -1.8965 2.7449 -2.2217 61.4081
KYSE-220 GDSC1 -1.5042 6.2504 -2.946 55.4959
TE-12 GDSC1 -1.3326 17.5637 -7.9534 51.9659
FLO-1 GDSC1 0.7922 21.4028 -7.8838 46.2367
SK-GT-4 GDSC1 1.5105 5.1709 0.6657 28.5016
ESO-26 GDSC1 3.1516 5.8736 1.9232 12.0361
ESO-51 GDSC1 5.2353 7.2581 2.6601 1.4049
HCE-4 GDSC1 5.7661 7.8274 2.6706 0.8656
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 -3.2481 3.9217 -3.7035 55.0976
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-6 GDSC1 -2.1037 7.9151 -4.2581 57.4745
KP-N-YS GDSC1 -1.6983 2.6088 -1.9752 60.0491
IMR-32 CTRP2 -1.5626 2.3196 -1.6375 45.1766
GI-ME-N GDSC1 -1.048 7.0059 -2.7741 52.5099
SJNB-7 GDSC1 -0.9469 0.9218 -0.9576 53.7186
CHP-212 GDSC1; CTRP2 -0.6689 4.8558 -1.1127 40.1992
MHH-NB-11 GDSC1 -0.6591 9.8201 -3.6234 50.0756
SJNB-17 GDSC1 -0.5597 22.1187 -9.4596 49.7986
SK-N-DZ GDSC1; CTRP2 -0.2615 4.2477 -0.5287 37.1705
CHP-134 GDSC1 -0.0825 14.1338 -5.1114 47.8986
IMR-5 GDSC1 0.0236 5.575 -1.0587 44.517
NB69 GDSC1 0.1888 3.3616 -0.102 40.8758
Kelly GDSC1; CTRP2 0.194 8.8728 -1.567 37.8559
SK-N-BE(2) CTRP2 0.319 9.4701 -1.6854 41.9617
SJNB-13 GDSC1 0.3201 7.5446 -1.6023 43.4914
NH-12 GDSC1 0.4418 4.619 -0.2406 39.4918
TGW GDSC1 0.697 8.5603 -1.6954 41.5734
SK-N-AS GDSC1; CTRP2 0.805 8.872 -0.9265 34.4068
SK-N-MC-IXC GDSC1 0.9434 3.8186 0.5836 32.335
NH-6 CTRP2 1.6574 8.09 0.2916 28.3056
SJNB-10 GDSC1 1.7064 9.4139 -1.1376 35.2611
SiMa GDSC1 1.9155 13.8858 -3.1527 38.9339
CHP-126 GDSC1; CTRP2 2.1498 10.4075 -0.2348 28.501
SK-N-SH GDSC1; CTRP2 2.3153 7.5611 1.2006 23.2833
SK-N-FI GDSC1; CTRP2 2.4312 8.1587 1.0651 23.4496
SJNB-5 GDSC1 2.4487 4.7396 1.8143 15.8877
SJNB-12 GDSC1 2.5868 15.0263 -3.1318 36.6196
GOTO GDSC1 2.6676 8.4464 0.2166 25.3933
NB(TU)1 GDSC1 3.2439 8.3098 0.7851 19.7601
SK-N-BE(2)-M17 GDSC1 3.6384 14.9009 -2.1827 31.0575
LA-N-6 GDSC1 4.2043 9.888 0.7673 16.5038
SJNB-14 GDSC1 4.4125 10.6048 0.5701 17.0419
NB1 GDSC1; CTRP2 4.506 14.3665 0.0323 21.9167
KP-N-YN GDSC1; CTRP2 7.3738 19.0171 0.0159 16.6135
KP-N-SI9s CTRP2 8.5414 16.3672 2.1026 7.7042
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 0.0074 4.795 -0.7721 44.12
SNU-478 CTRP2 1.8391 7.323 0.7969 26.0829
SNU-1196 CTRP2 3.2717 8.0683 1.9605 17.8546
SNU-869 CTRP2 6.2893 11.4001 2.9615 7.5288
HuH-28 CTRP2 6.5232 9.2034 4.1721 2.3778
SNU-308 CTRP2 7.1352 9.1575 4.5164 0.7122
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC1 -3.5838 4.0096 -4.4057 68.3669
MDA-MB-453 GDSC1; CTRP2 -2.2516 2.4785 -2.3821 49.6381
Evsa-T GDSC1 -1.743 0.6777 -1.7644 62.918
MDA-MB-175-VII GDSC1 -1.7239 1.9772 -1.8814 61.0829
OCUB-M GDSC1 -1.3496 -0.0648 -1.35 58.7984
HCC1599 GDSC1 -1.0536 3.8593 -1.6026 53.6501
MDA-MB-361 GDSC1; CTRP2 -0.7223 3.6273 -0.9108 39.9559
HCC1569 GDSC1; CTRP2 -0.7101 7.402 -1.9588 41.8718
HCC2218 GDSC1; CTRP2 -0.4908 5.9777 -1.237 39.74
MDA-MB-415 GDSC1; CTRP2 -0.2878 3.7798 -0.4688 37.102
BT-483 GDSC1 -0.2636 9.2262 -2.9556 47.9451
CAL-85-1 GDSC1; CTRP2 -0.1783 5.9899 -0.9007 37.7937
MRK-nu-1 GDSC1 -0.0487 1.0016 -0.0494 42.5646
BT-549 GDSC1; CTRP2 0.176 8.9336 -1.6109 38.0031
UACC-812 GDSC1 0.2425 9.9303 -2.785 45.3058
Hs 578T GDSC1; CTRP2 0.327 5.1647 -0.1067 33.8362
UACC-893 GDSC1 0.4161 2.3547 0.3552 37.1019
DU4475 GDSC1; CTRP2 0.6305 6.4755 -0.1829 33.0169
BT-474 GDSC1; CTRP2 0.6388 4.6848 0.3543 31.3355
MDA-MB-468 GDSC1; CTRP2 0.8251 3.6337 0.7449 29.4243
HCC1419 GDSC1; CTRP2 0.9101 8.4405 -0.6369 33.3376
HCC38 GDSC1; CTRP2 1.0178 8.9495 -0.7376 33.2523
HCC1187 GDSC1 1.2114 4.5571 0.6052 30.5702
HCC70 GDSC1 1.221 3.6083 0.9526 28.4092
BT-20 GDSC1; CTRP2 1.3222 5.2722 0.9499 27.1275
EFM-19 GDSC1 1.4728 11.5196 -2.3848 39.2721
CAL-120 GDSC1; CTRP2 1.6521 10.5927 -0.8165 31.526
T-47D GDSC1; CTRP2 1.6914 7.2705 0.6613 26.9851
HCC1500 GDSC1; CTRP2 2.0237 13.3878 -1.7647 32.7256
HCC1937 GDSC1; CTRP2 2.0351 8.3039 0.5936 26.2067
JIMT-1 GDSC1; CTRP2 2.0975 7.8797 0.8394 25.1855
COLO 824 GDSC1 2.2287 9.7297 -0.813 31.8548
CAMA-1 GDSC1; CTRP2 2.2572 7.5901 1.1277 23.7104
CAL-51 GDSC1; CTRP2 2.3808 7.7778 1.1773 23.1843
Hs 578Bst CTRP2 2.5323 12.6399 -0.9191 29.3675
MDA-MB-330 GDSC1 2.7901 7.2119 0.9384 20.6038
EFM-192A GDSC1; CTRP2 2.7943 4.2429 2.7613 16.1715
MDA-MB-157 GDSC1; CTRP2 2.8486 11.5712 -0.1033 26.237
HCC202 CTRP2 3.0828 13.2517 -0.6972 27.3737
MFM-223 GDSC1 3.0999 10.9956 -0.6791 27.8388
AU565 GDSC1; CTRP2 3.2401 7.8121 2.0447 18.9306
CAL-148 GDSC1; CTRP2 3.3681 12.3999 -0.0159 24.6685
HDQ-P1 GDSC1; CTRP2 3.6989 11.473 0.7443 21.3543
HCC1428 GDSC1; CTRP2 3.7826 8.7437 2.1474 15.853
YMB-1-E GDSC1 4.0992 6.9626 2.1284 7.2805
SK-BR-3 CTRP2 4.2341 16.2558 -1.1462 25.924
HCC1395 GDSC1; CTRP2 4.7577 13.9586 0.4529 20.0021
MDA-MB-436 GDSC1 4.7919 10.5605 0.8691 14.0957
ZR-75-30 GDSC1; CTRP2 4.9831 9.5565 2.8446 10.3557
MCF-7 GDSC1; CTRP2; CTRP1 5.3 6.8241 4.4763 2.906
KPL-1 CTRP2 5.4508 7.8069 4.106 4.1851
MDA-MB-231 GDSC1; CTRP2 6.3591 15.0771 1.1979 14.2997
HCC1954 GDSC1; CTRP2 6.7105 11.8491 3.0421 6.5631
ZR-75-1 CTRP2 6.8563 8.3106 4.7237 0.3513
HCC1806 GDSC1; CTRP2 7.3406 8.8411 4.7212 0.1961
HCC1143 CTRP2 8.497 10.9922 4.3913 0.4065
HMC-1-8 CTRP2 8.5657 16.729 1.9488 8.2306
BT 248 CTRP2 -0.271 7.889 -1.6694 39.7142
BT 145 CTRP2 -0.1976 6.8693 -1.2156 38.5631
BT164 CTRP2 0.4245 7.3684 -0.728 35.195
BT 239 CTRP2 0.5917 12.8758 -2.9245 38.8477
BT 112 CTRP2 0.7585 7.9087 -0.5812 33.6878
BT 416 CTRP2 0.8044 4.5842 0.5573 30.1206
BT 271 CTRP2 0.8673 7.0035 -0.1168 32.035
BT 330 CTRP2 0.9929 7.6884 -0.2453 31.999
BT 482 CTRP2 1.0617 6.6744 0.2126 30.4016
BT 286 CTRP2 1.1394 7.7812 -0.1269 31.1868
BT 131 CTRP2 1.3644 7.4206 0.2548 29.3145
BT 231 CTRP2 1.3724 11.9608 -1.7259 34.4542
BT 422 CTRP2 1.9911 11.0756 -0.7022 30.2571
BT 428 CTRP2 1.9964 4.4053 1.8852 21.7457
BT 245 CTRP2 2.0951 8.0288 0.7736 25.4207
BT 444 CTRP2 2.1824 11.246 -0.5938 29.4326
BT147 CTRP2 2.3276 8.5671 0.7795 24.7452
BT 359 CTRP2 2.4845 13.3498 -1.307 30.4674
BT 172 CTRP2 2.5281 8.5849 0.9758 23.5032
BT 340 CTRP2 2.8809 13.1721 -0.847 28.2842
BT 159 CTRP2 3.1894 15.263 -1.5863 29.3903
BT 333 CTRP2 3.2964 13.6116 -0.6759 26.7931
BT 139 CTRP2 3.3159 15.7212 -1.6973 29.353
BT 504 CTRP2 3.3622 13.176 -0.4015 25.8498
BT 440 CTRP2 3.5335 13.6804 -0.4927 25.7064
BT 228 CTRP2 3.6745 18.2902 -2.6503 30.5996
BT 328 CTRP2 3.6967 10.9447 1.0007 20.4458
BT 232 CTRP2 3.8152 12.5716 0.3104 22.5584
BT 179 CTRP2 3.9281 13.3455 0.0297 23.2058
BT 216 CTRP2 4.0478 13.1825 0.2178 22.3294
BT 320 CTRP2 5.2991 15.2963 0.2406 19.606
BT 498 CTRP2 5.9392 15.1289 0.844 16.3239
BT 187 CTRP2 6.8428 20.0299 -0.8874 20.1941
BT 224 CTRP2 8.8348 20.5204 0.3241 13.4329
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.3276 14.4881 1.4659 13.3633
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-247MG GDSC1 -5.4943 -0.3452 -5.5993 85.1945
AM-38 GDSC1 -2.9569 8.359 -5.3355 60.543
MOG-G-CCM GDSC1 -1.6138 6.8137 -3.2883 55.7817
D-336MG GDSC1 -1.5073 3.2714 -1.9286 57.784
D-423MG GDSC1 -1.3777 4.0018 -1.9997 56.1514
GI-1 GDSC1 -1.065 2.3043 -1.2277 54.5348
MOG-G-UVW GDSC1 -0.4899 4.3969 -1.1652 48.6222
Onda 11 GDSC1 -0.3148 9.3386 -3.0584 48.2478
D-566MG GDSC1 -0.2751 2.1715 -0.3574 45.6418
D-502MG GDSC1 -0.203 9.8832 -3.2001 47.7418
YKG-1 GDSC1; CTRP2 -0.1571 6.6022 -1.0791 38.1182
SF539 GDSC1; CTRP2 -0.0547 5.9495 -0.7534 36.9764
LN-405 GDSC1 -0.03 8.4856 -2.3823 46.3641
GaMG GDSC1; CTRP2; CTRP1 0.0047 6.6668 -0.9261 37.1706
Hs 683 GDSC1; CTRP2 0.148 6.627 -0.7574 36.2446
Becker GDSC1; CTRP2 0.1739 7.4801 -1.0383 36.816
KALS-1 GDSC1; CTRP2 0.2091 7.3098 -0.9369 36.4572
M059J GDSC1 0.2503 5.3616 -0.7333 42.2686
YH-13 GDSC1; CTRP2 0.5412 5.7179 -0.0326 32.8764
SNB-75 GDSC1; CTRP2 0.8063 8.7019 -0.8541 34.2257
M059K CTRP2 0.8442 7.6483 -0.3874 32.8824
NMC-G1 GDSC1; CTRP2 0.9933 7.6611 -0.2341 31.9656
KS-1 [Human Krukenberg tumour] GDSC1 1.0428 6.3984 -0.3547 36.0658
U-118MG GDSC1; CTRP2 1.0532 11.8166 -1.9766 35.8919
H4 GDSC1 1.2128 11.4401 -2.5865 40.7024
SF268 GDSC1; CTRP2 1.2398 10.0476 -0.9872 33.1841
KNS-81-FD GDSC1 1.5491 14.861 -3.9639 41.3507
GB-1 GDSC1; CTRP2 1.6607 7.6317 0.4841 27.6696
ONS-76 GDSC1; CTRP2 1.6788 6.7812 0.8365 26.4232
SW1088 GDSC1; CTRP2 1.7208 6.372 1.0315 25.6169
Onda 10 GDSC1 1.7272 9.3243 -1.0745 34.9717
42-MG-BA GDSC1; CTRP2 1.8385 11.6425 -1.1174 31.7481
KINGS-1 GDSC1 1.8581 14.4736 -3.4956 39.6712
GMS-10 CTRP2 2.1287 9.8866 -0.0161 27.904
SF295 GDSC1; CTRP2; CTRP1 2.172 6.5799 1.4405 22.8178
DK-MG GDSC1; CTRP2 2.2747 10.9851 -0.3807 28.5806
GOS-3 CTRP2 2.3164 9.7081 0.2535 26.5358
LNZTA3WT4 GDSC1 2.5115 10.2264 -0.806 30.6419
D-392MG GDSC1 2.5232 10.1041 -0.7348 30.323
SF126 GDSC1; CTRP2 2.7135 8.734 1.0964 22.5702
TM-31 CTRP2 3.0507 9.9958 0.8436 22.5955
Daoy GDSC1; CTRP2 3.2858 6.6993 2.5754 15.4195
CAS-1 GDSC1; CTRP2 3.2997 10.3613 0.9092 21.7367
SNU-489 CTRP2 3.3283 9.4485 1.3727 19.9667
U-87MG ATCC GDSC1; CTRP2 3.3359 16.2601 -1.9456 29.8715
D-542MG GDSC1 3.7648 11.3583 -0.3097 23.831
SNU-738 CTRP2 3.8226 10.4462 1.3613 18.8169
D283 Med GDSC1; CTRP2 3.8982 6.6314 3.2403 11.1931
SK-MG-1 GDSC1 3.9388 10.7744 0.1207 21.0942
T98G GDSC1; CTRP2 4.3022 8.558 2.7298 12.2858
DBTRG-05MG GDSC1; CTRP2 4.3135 12.3665 0.8594 19.5453
KNS-81 CTRP2 4.6127 9.9094 2.3453 13.1782
U-251MG GDSC1; CTRP2 4.6304 15.8767 -0.6141 23.611
A-172 GDSC1; CTRP2 4.7333 8.2646 3.269 9.1065
KG-1-C CTRP2 5.2671 25.2712 -4.7735 31.2162
8-MG-BA GDSC1; CTRP2 5.2778 9.3861 3.1778 8.3893
PFSK-1 GDSC1 5.3308 7.8446 2.4656 2.3405
CCF-STTG1 CTRP2 5.3942 16.6858 -0.3755 21.3561
D-263MG GDSC1 5.4631 7.0745 2.8274 0.5041
LN-229 GDSC1; CTRP2; CTRP1 5.6168 13.2329 1.532 14.3963
KNS-60 CTRP2 5.972 11.1216 2.8623 8.4544
SNU-1105 CTRP2 6.4435 8.8244 4.2974 2.0018
SW1783 GDSC1; CTRP2 6.558 17.0883 0.3531 16.8943
LN-18 GDSC1; CTRP2 6.6106 7.6003 4.8873 0.1306
KNS-42 GDSC1; CTRP2 6.6513 17.7374 0.1028 17.5478
SNU-466 CTRP2 7.7986 19.5582 0.0618 15.7944
SNU-201 CTRP2 7.8728 14.8762 2.3747 7.5527
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 4.6454 8.0427 1.9805 6.9246
TGBC24TKB GDSC1 5.4335 7.7601 2.5503 1.7402
TGBC1TKB GDSC1 5.6188 7.1241 2.8688 0.3093
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 -2.3161 0.5084 -2.3234 50.044
JHUEM-7 CTRP2 -1.6608 3.3196 -1.8697 45.9921
JHUEM-1 CTRP2 -1.6088 1.4493 -1.6294 45.3843
AN3-CA GDSC1; CTRP2 -1.4862 2.8531 -1.615 44.7704
MFE-319 GDSC1; CTRP2; CTRP1 -0.2826 2.2695 -0.303 36.588
HEC-6 CTRP2; CTRP1 0.1211 3.31 0.0365 34.1124
HEC-265 CTRP2; CTRP1 0.7327 3.4735 0.6656 29.9948
HEC-1-A CTRP2 1.0826 7.2268 0.0298 30.8995
HEC-151 CTRP2; CTRP1 1.1326 5.6058 0.6461 28.7628
ESS-1 GDSC1; CTRP2 1.4794 8.2899 0.0219 29.6855
JHUEM-3 CTRP2 1.4818 3.2963 1.4639 24.8484
KLE GDSC1; CTRP2; CTRP1 1.5872 10.3384 -0.766 31.5853
MFE-280 GDSC1 1.8047 6.9065 0.1661 29.6537
EN GDSC1; CTRP2 2.2654 7.15 1.3171 23.0006
MFE-296 GDSC1; CTRP2 3.355 6.4082 2.7671 14.4912
RL95-2 GDSC1; CTRP2 4.4191 8.0357 3.0936 10.5255
EFE-184 CTRP2 4.6226 9.3075 2.6529 11.8973
HEC-251 CTRP2; CTRP1 5.3821 8.4175 3.7469 5.8115
HEC-59 CTRP2; CTRP1 5.4034 6.4894 4.723 1.6964
HEC-108 CTRP2; CTRP1 5.4767 6.3472 4.8449 1.0847
HEC-1-B CTRP2 8.4872 16.748 1.8896 8.5444
HEC-50B CTRP2 9.5141 20.828 0.6303 11.5388
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 5.3142 6.2323 4.7825 1.5994
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-195 GDSC1 -4.4089 6.4841 -6.1391 67.3119
KTCTL-21 GDSC1 -2.5503 2.1695 -2.8088 66.8985
RXF 393L GDSC1 -1.5886 6.8431 -3.2737 55.6302
UO-31 GDSC1; CTRP2 -1.3824 5.567 -2.0851 44.8937
NCC021 GDSC1 -1.0426 3.8964 -1.6021 53.5407
KTCTL-140 GDSC1 -0.8574 2.4936 -1.0387 52.3066
KTCTL-1M GDSC1 -0.4322 3.284 -0.7587 47.8098
CAL-54 GDSC1; CTRP2 0.2346 8.3065 -1.2947 37.163
786-O GDSC1; CTRP2 2.0705 4.1008 2.0107 21.0759
KMRC-2 CTRP2 2.3842 8.8884 0.6938 24.8845
ACHN GDSC1; CTRP2 2.7189 11.8327 -0.353 27.3173
KTCTL-13 GDSC1 2.8722 8.7464 0.2478 24.3739
BB65-RCC GDSC1 3.0445 10.2869 -0.3722 26.7364
VMRC-RCW GDSC1; CTRP2; CTRP1 3.0616 7.7607 1.8861 18.6876
TK-10 GDSC1 3.0958 6.0342 1.7944 13.2421
LB1047-RCC GDSC1 3.1731 4.5527 2.5992 6.667
TUHR10TKB CTRP2 3.557 7.9146 2.3164 15.7331
KTCTL-26A GDSC1 3.8025 8.4916 1.1503 15.3415
BFTC-909 GDSC1; CTRP2 3.9508 11.7459 0.8409 20.4267
KMRC-1 GDSC1; CTRP2 3.9552 5.0979 3.8694 8.6375
SW156 GDSC1 4.2259 8.3983 1.5181 11.413
TUHR14TKB CTRP2 5.017 24.1422 -4.4177 40.7391
HA7-RCC GDSC1 5.0698 7.9352 2.2878 3.8704
SW13 GDSC1 5.1452 9.999 1.3812 9.8366
SN12C GDSC1 5.167 10.4175 1.1967 10.9929
TUHR4TKB CTRP2 5.1834 11.1158 2.2345 12.463
A-498 GDSC1 5.3139 6.846 2.8521 0.5108
RCC10RGB GDSC1; CTRP2; CTRP1 5.5034 16.6206 -0.2531 23.1413
VMRC-RCZ GDSC1; CTRP2 5.8592 10.2502 3.208 7.2206
LB2241-RCC GDSC1 5.9079 7.82 2.7301 0.5645
LB996-RCC GDSC1 6.0938 8.1902 2.6681 0.658
A-704 GDSC1 6.1209 8.0947 2.7131 0.5055
Caki-1 GDSC1; CTRP2 6.7675 12.8611 2.5915 8.2747
KMRC-20 GDSC1; CTRP2 6.986 8.5732 4.6785 0.394
769-P GDSC1; CTRP2 7.2023 8.9185 4.6382 0.39
OS-RC-2 GDSC1; CTRP2 7.2835 9.5804 4.4153 0.8957
SNU-1272 CTRP2 8.2839 17.5801 1.3607 10.7104
Caki-2 CTRP2 10.7926 19.2111 2.1317 5.2172
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 60 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H747 GDSC1; CTRP2 -1.5393 4.1117 -1.8876 45.4081
SW626 GDSC1 -1.447 5.9146 -2.7535 55.3514
COLO 320 CTRP2; CTRP1 -0.9043 9.0994 -2.8173 48.1671
C2BBe1 GDSC1; CTRP2; CTRP1 -0.6343 4.418 -0.9707 39.7419
SW480 CTRP1 -0.3014 9.4464 -2.3237 60.622
HCT 116 GDSC1; CTRP2; CTRP1 -0.0681 3.8135 -0.2379 35.6268
SW48 GDSC1; CTRP2; CTRP1 -0.0165 6.0254 -0.7359 36.7916
SNU-1040 GDSC1; CTRP1 -0.0108 5.9619 -0.7095 52.1424
LS123 GDSC1; CTRP2; CTRP1 0.6695 9.3257 -1.2595 35.6186
LS411N GDSC1; CTRP2; CTRP1 0.7189 5.3652 0.2654 31.3551
LS513 GDSC1; CTRP2; CTRP1 0.8147 4.44 0.5993 29.947
GP2d CTRP2; CTRP1 0.8223 5.0507 0.464 30.3706
MDST8 GDSC1; CTRP2; CTRP1 0.8907 8.3324 -0.6128 33.3375
CL-34 CTRP1 1.2297 4.6514 1.0049 55.5288
SNU-C5 GDSC1; CTRP2; CTRP1 1.2783 7.221 0.2409 29.6264
SNU-C2A CTRP2; CTRP1 1.3622 7.6494 0.1615 29.6148
SNU-81 GDSC1; CTRP1 1.4801 4.8034 1.2427 38.8352
KM12 GDSC1; CTRP2; CTRP1 1.5062 6.9613 0.5836 27.8064
LS1034 GDSC1; CTRP2 1.5685 6.1936 0.9295 26.435
CL-40 CTRP1 1.6234 5.1276 1.3179 50.9831
HCT 15 GDSC1; CTRP2 1.6248 7.6955 0.4202 27.9873
SW620 GDSC1; CTRP2; CTRP1 1.6654 8.0633 0.3111 28.2194
SW403 CTRP1 1.782 16.777 -3.631 49.7395
SW1417 GDSC1; CTRP2 1.803 10.8453 -0.7819 31.0007
SW837 GDSC1 1.9335 6.7467 0.3667 27.9631
SK-CO-1 CTRP2; CTRP1 1.9424 5.4318 1.5809 22.9897
SNU-503 CTRP2 1.9806 9.4723 0.0225 28.205
RKO GDSC1; CTRP2; CTRP1 2.0911 8.3379 0.6368 25.9006
SNU-C4 CTRP2; CTRP1 2.2379 5.7442 1.8062 21.2871
COLO 320HSR GDSC1 2.5302 10.8254 -1.0873 31.5783
CL-11 GDSC1; CTRP2 2.5906 10.0026 0.3898 25.3476
SNU-C2B GDSC1 2.7544 9.1234 -0.0432 26.353
CaR-1 GDSC1 2.7612 12.256 -1.5988 32.3373
T84 GDSC1; CTRP2 2.768 5.8985 2.3295 17.8037
HCT 8 CTRP2; CTRP1 2.8417 7.9092 1.5958 20.3779
OUMS-23 CTRP2 2.9628 5.5148 2.6679 15.9824
SNU-C1 GDSC1; CTRP2 3.1439 4.3409 3.1198 13.8167
SNU-175 GDSC1; CTRP1 3.6411 7.4939 2.5933 21.8597
GP5d GDSC1 4.0891 6.7517 2.2236 6.5896
SW948 GDSC1; CTRP2; CTRP1 4.2903 5.9957 3.9197 7.4902
SNU-407 GDSC1; CTRP2 4.6469 10.802 1.9316 14.7706
CW-2 GDSC1; CTRP2; CTRP1 4.6947 10.3363 2.2053 13.5728
SW1463 GDSC1 5.1127 7.4493 2.5217 2.3299
HCC2998 GDSC1 5.1855 7.6705 2.4652 2.5564
HT115 GDSC1; CTRP2; CTRP1 5.234 6.3377 4.6656 2.2348
COLO205 GDSC1; CTRP2; CTRP1 5.3215 7.4135 4.1994 4.0269
LS180 GDSC1; CTRP2; CTRP1 5.3609 7.1528 4.361 3.2787
HT-55 GDSC1; CTRP2; CTRP1 5.4424 8.5049 3.7516 5.6824
DLD-1 CTRP2; CTRP1 5.4879 8.7322 3.6744 5.9235
HCC-56 CTRP2 5.6391 7.0026 4.6408 1.6742
LoVo GDSC1; CTRP2; CTRP1 5.682 11.767 2.3157 11.1931
RCM-1 [Human ESC] GDSC1; CTRP2; CTRP1 5.7118 11.7984 2.3237 11.1066
COLO 678 GDSC1; CTRP2; CTRP1 5.7998 14.91 0.8419 16.5897
SW1116 GDSC1; CTRP2 5.9686 13.5287 1.6644 13.2435
CCK-81 GDSC1; CTRP2 6.4087 12.5937 2.4629 9.3507
SNU-61 GDSC1; CTRP2; CTRP1 6.6418 11.1137 3.3489 5.4357
NCI-H508 CTRP2; CTRP1 6.7276 11.5421 3.2016 5.9017
HT-29 GDSC1; CTRP2; CTRP1 7.0302 8.2782 4.8044 0.1501
NCI-H716 GDSC1; CTRP2 7.3161 13.2805 2.7657 6.8015
COLO201 CTRP2 11.7317 23.8906 0.5819 9.1317
⏷ Show the Full List of 60 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 -2.7215 9.0496 -5.3821 59.1686
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 -1.7327 5.0512 -2.3241 46.7851
SNU-423 GDSC1; CTRP2 -0.4813 5.9359 -1.2136 39.6546
SNU-449 GDSC1; CTRP2; CTRP1 -0.3815 5.6633 -1.0218 38.851
HuH-6 CTRP2 0.7295 5.2257 0.3159 31.1578
SNU-886 CTRP2 1.4291 3.7507 1.3717 25.3324
JHH-1 GDSC1; CTRP2 1.4455 5.4929 1.021 26.4955
SNU-398 GDSC1; CTRP2; CTRP1 1.5971 11.9661 -1.5064 33.3373
PLC/PRF/5 CTRP2 2.1796 6.3129 1.5473 22.4052
HLE GDSC1 3.1404 4.2667 2.7106 5.9301
SNU-761 CTRP2 3.2598 7.8882 2.0303 17.6133
HLF CTRP2 3.3642 11.9632 0.1938 24.012
SK-HEP-1 GDSC1; CTRP2 4.1651 9.8039 1.9928 15.5799
SNU-475 GDSC1; CTRP2 4.171 6.7549 3.4622 9.6123
JHH-2 GDSC1; CTRP2 4.2781 9.8572 2.0701 15.0177
Huh-7 GDSC1 4.5661 6.5694 2.6106 2.681
JHH-5 CTRP2 4.794 7.6243 3.6404 7.4297
JHH-7 GDSC1 5.1546 7.8205 2.3847 3.0992
Hep-G2/C3A GDSC1 5.3642 6.8174 2.882 0.3878
JHH-6 GDSC1; CTRP2; CTRP1 5.4556 9.4593 3.286 7.6054
Hep-G2 CTRP2; CTRP1 6.2391 8.278 4.4247 1.7583
SNU-878 CTRP2 6.2809 8.6336 4.2866 2.2294
SNU-387 GDSC1; CTRP2 6.5997 10.0454 3.8286 3.5983
JHH-4 GDSC1; CTRP2 6.6053 10.0935 3.8097 3.665
HuH-1 GDSC1; CTRP2 7.0324 8.6769 4.6586 0.4177
Hep 3B2.1-7 GDSC1; CTRP2 7.2804 8.845 4.6967 0.2515
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 217 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1048 GDSC1; CTRP1 -4.9869 2.3993 -5.296 79.6534
IST-SL2 GDSC1 -4.9489 2.0147 -5.3795 77.1837
NCI-H2073 CTRP1 -4.5676 4.9812 -5.399 79.9092
SBC-3 GDSC1 -4.1867 -1.4265 -4.1928 86.0384
NCI-H847 GDSC1 -3.851 3.8424 -4.6472 69.6859
NCI-H64 GDSC1 -3.5715 -2.5254 -3.5715 86.0003
SBC-1 GDSC1 -3.4217 0.3035 -3.4829 76.7097
COR-L311 GDSC1 -3.3221 0.4254 -3.3887 75.8199
NCI-H520 GDSC1; CTRP2 -3.017 3.3002 -3.3284 54.0585
DMS 273 GDSC1; CTRP2; CTRP1 -2.2688 4.3285 -2.7292 49.7706
COR-L303 GDSC1 -2.2064 2.3959 -2.4818 64.1928
EPLC-272H GDSC1; CTRP2; CTRP1 -2.1291 2.3667 -2.2394 48.8602
NCI-H596 GDSC1; CTRP1 -2.0809 3.5593 -2.3646 67.2961
Lu-139 GDSC1 -2.0685 4.1243 -2.7902 60.7267
SCLC-21H CTRP1 -1.9242 8.8166 -3.7901 67.1354
NCI-H1703 GDSC1; CTRP2 -1.8985 6.9651 -3.0894 48.0022
NCI-H1975 GDSC1; CTRP1 -1.8465 5.5933 -2.599 63.164
COLO 699 CTRP2; CTRP1 -1.7406 7.7226 -3.1845 47.3434
IST-SL1 GDSC1 -1.6915 4.8047 -2.6065 57.6635
COR-L23 GDSC1; CTRP1 -1.5608 3.5884 -1.808 64.3448
CAL-12T GDSC1; CTRP2; CTRP1 -1.5408 4.3067 -1.9319 45.4679
NCI-H1963 CTRP1 -1.5229 4.8856 -2.0519 73.1132
NCI-H1876 GDSC1; CTRP1 -1.403 4.2145 -1.7617 62.557
NCI-H2227 GDSC1 -1.3699 9.1927 -4.0554 53.5661
COR-L279 CTRP2; CTRP1 -1.3637 8.2387 -2.9707 45.6291
HCC78 GDSC1; CTRP2; CTRP1 -1.3 4.2202 -1.6509 43.9434
NCI-H1648 GDSC1 -1.2673 1.4434 -1.3242 57.185
LC-2/ad GDSC1 -1.1513 7.2154 -2.9702 53.0523
DMS 114 GDSC1; CTRP2 -1.1367 5.2066 -1.7155 43.2994
NCI-H1304 GDSC1 -1.0378 8.2252 -3.288 52.1743
EMC-BAC-2 GDSC1 -0.9791 6.322 -2.4193 52.2549
LCLC-97TM1 GDSC1; CTRP2; CTRP1 -0.9761 7.0131 -2.1073 43.1548
NCI-H2171 GDSC1 -0.9262 5.725 -2.1253 52.0422
ABC-1 GDSC1 -0.9049 8.5019 -3.2743 51.422
NCI-H1341 CTRP2 -0.8156 2.0052 -0.8389 40.1363
HCC44 GDSC1; CTRP2; CTRP1 -0.8134 6.0117 -1.5989 41.7238
SK-MES-1 GDSC1; CTRP2 -0.7528 4.9992 -1.2412 40.8129
NCI-H446 GDSC1; CTRP2 -0.7407 4.8764 -1.1963 40.6713
NCI-H748 GDSC1 -0.6186 4.1372 -1.2175 49.7703
NCI-H524 GDSC1 -0.6088 22.0146 -9.4533 49.916
EBC-1 GDSC1; CTRP2; CTRP1 -0.5649 4.7943 -0.9839 39.4924
Ms-1 GDSC1 -0.5413 7.0744 -2.2763 49.3329
NCI-H2085 GDSC1; CTRP2 -0.5183 8.0018 -1.9767 41.1545
NCI-H1793 GDSC1; CTRP2; CTRP1 -0.517 6.5435 -1.4493 40.2574
NCI-H2196 GDSC1; CTRP2 -0.341 5.3125 -0.8764 38.3598
NCI-H1568 GDSC1; CTRP2; CTRP1 -0.3393 4.2876 -0.6215 37.7149
NCI-H69 GDSC1 -0.2975 6.5123 -1.7836 47.5404
NCI-H3122 GDSC1 -0.2797 8.6956 -2.7287 47.9351
NCI-H1836 GDSC1; CTRP1 -0.2306 9.8686 -2.4263 52.5507
COR-L51 CTRP2; CTRP1 -0.1491 9.4137 -2.1506 40.0747
NCI-H211 GDSC1; CTRP2 -0.1306 7.5317 -1.3841 38.6566
EMC-BAC-1 GDSC1 -0.0369 7.2223 -1.8212 45.9049
NCI-H187 GDSC1 0.0836 7.6602 -1.8935 45.2603
HOP-92 GDSC1; CTRP2 0.1203 13.2767 -3.5791 41.0915
NCI-H1155 GDSC1; CTRP2 0.1606 8.5311 -1.4631 37.7674
NCI-H2135 GDSC1 0.1858 10.4016 -3.0632 45.8046
COR-L321 GDSC1 0.2086 8.8313 -2.3037 45.0109
Lu-134-A GDSC1 0.3404 6.7422 -1.2234 42.7156
NCI-H209 GDSC1; CTRP2 0.363 7.2924 -0.7653 35.5017
HCC2935 CTRP2; CTRP1 0.378 5.7078 -0.2073 33.9539
HCC1833 CTRP2; CTRP1 0.4473 9.2846 -1.4734 36.8081
NCI-H1437 GDSC1; CTRP1 0.4478 4.8872 0.0972 48.5947
NCI-H841 GDSC1; CTRP2; CTRP1 0.4646 6.8289 -0.4865 34.4304
NCI-H2030 GDSC1; CTRP2; CTRP1 0.5174 8.7846 -1.191 35.9707
CPC-N GDSC1 0.547 12.0388 -3.5022 44.5902
NCI-H358 GDSC1; CTRP2; CTRP1 0.5497 7.5487 -0.6626 34.5998
NCI-H1693 GDSC1; CTRP2 0.5501 7.3632 -0.5915 34.4143
UMC-11 GDSC1 0.5676 6.1279 -0.7217 40.1337
COLO 668 GDSC1; CTRP1 0.6071 9.8123 -1.5331 48.2613
NCI-H2347 GDSC1 0.6187 12.8122 -3.8102 44.5671
NCI-H2122 GDSC1; CTRP2; CTRP1 0.6227 2.3186 0.6186 30.5151
NCI-H1694 GDSC1; CTRP2; CTRP1 0.6291 8.2184 -0.8421 34.7813
HCC1359 CTRP1 0.6326 21.8952 -7.199 52.7494
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2; CTRP1 0.661 6.9061 -0.3028 33.256
NCI-H1792 GDSC1; CTRP2; CTRP1 0.6716 6.1939 -0.0428 32.4659
Lu-99 CTRP2; CTRP1 0.6766 5.8129 0.0855 32.0597
NCI-H1581 GDSC1; CTRP2 0.7372 6.4859 -0.071 32.3303
NCI-H1930 CTRP1 0.742 7.8592 -0.5791 56.7771
RERF-LC-KJ GDSC1; CTRP1 0.7878 8.7012 -0.8731 46.9585
NCI-H1944 GDSC1; CTRP2; CTRP1 0.7992 4.7937 0.5032 30.3173
NCI-H810 GDSC1; CTRP2; CTRP1 0.7996 10.414 -1.5989 35.9217
HCC2108 CTRP2; CTRP1 0.8055 6.4248 0.0241 31.818
NCI-H2009 GDSC1; CTRP2; CTRP1 0.8583 7.3646 -0.2625 32.4858
NCI-H1993 GDSC1 0.8594 10.7358 -2.5763 42.2102
NCI-H1666 GDSC1; CTRP2; CTRP1 0.8794 5.2945 0.4605 30.1953
NCI-H23 GDSC1; CTRP2; CTRP1 0.9362 7.2206 -0.1245 31.8325
NCI-H1395 CTRP2 0.9703 7.0821 -0.0356 31.4582
NCI-H2286 CTRP2; CTRP1 0.9902 8.7451 -0.68 33.1919
DMS 454 CTRP2 1.0686 9.5851 -0.9588 33.6439
NCI-H1573 GDSC1; CTRP2; CTRP1 1.0984 6.0022 0.4838 29.4115
RERF-LC-MS GDSC1; CTRP2 1.1146 5.0317 0.7878 28.3413
NCI-H2081 GDSC1; CTRP2; CTRP1 1.1187 9.7076 -0.9609 33.493
NCI-H522 GDSC1; CTRP2; CTRP1 1.1662 9.9202 -1.0059 33.4552
LK2 CTRP2 1.2155 4.6698 0.9854 27.3433
PaCa-3 GDSC1 1.216 9.5185 -1.6503 38.8999
HOP-62 GDSC1; CTRP2 1.2796 7.5068 0.1307 29.9672
Lu-65 GDSC1; CTRP2; CTRP1 1.3638 6.2669 0.6827 27.9119
NCI-H2141 GDSC1; CTRP2; CTRP1 1.3826 10.5998 -1.0907 33.0035
NCI-H82 GDSC1; CTRP1 1.4777 5.9491 0.9133 39.9392
NCI-H647 GDSC1; CTRP2 1.533 5.3311 1.1633 25.7269
BEN GDSC1; CTRP2; CTRP1 1.5502 6.9749 0.6255 27.5319
HCC1438 CTRP2 1.5975 7.3784 0.5189 27.7446
NCI-H1755 GDSC1; CTRP2; CTRP1 1.6196 9.6345 -0.4166 30.5457
EKVX GDSC1; CTRP2 1.6537 7.4582 0.5466 27.4834
NCI-H661 GDSC1; CTRP2; CTRP1 1.6604 9.0791 -0.1293 29.5961
SK-LU-1 GDSC1; CTRP2; CTRP1 1.6749 9.5792 -0.3357 30.154
LK-2 GDSC1 1.7233 10.3099 -1.5603 36.3771
NCI-H526 GDSC1; CTRP2 1.7234 11.3495 -1.0943 32.0175
HCC4006 CTRP2; CTRP1 1.7864 4.5109 1.6387 23.2682
KNS-62 CTRP2; CTRP1 1.963 7.84 0.7157 25.9999
NCI-H2110 GDSC1; CTRP2; CTRP1 1.9772 8.1388 0.6043 26.3375
NCI-H1355 GDSC1; CTRP2; CTRP1 2.0168 9.7506 -0.0665 28.3732
T3M-10 CTRP2; CTRP1 2.0382 8.7342 0.4095 26.8107
NCI-H1105 CTRP2; CTRP1 2.0653 9.6912 0.0092 28.005
COR-L95 GDSC1; CTRP2 2.1123 8.5665 0.5592 26.1023
LUDLU-1 CTRP2 2.1489 6.8715 1.3041 23.3814
VMRC-LCD CTRP2; CTRP1 2.2311 5.6018 1.8441 21.1696
Lu-135 GDSC1 2.2955 16.9508 -4.3441 39.4572
NCI-H2087 GDSC1; CTRP2 2.3904 10.0034 0.1912 26.5325
LCLC-103H GDSC1; CTRP2; CTRP1 2.4136 9.9403 0.2434 26.3021
NCI-H3255 GDSC1; CTRP1 2.4228 5.0284 2.2157 29.3473
HCC827 GDSC1; CTRP2; CTRP1 2.4804 8.2513 1.0751 23.2778
HCC366 CTRP2 2.4815 8.1454 1.1226 23.1039
NCI-H322M GDSC1 2.4816 12.4811 -1.9542 34.3653
NCI-H2170 GDSC1; CTRP2 2.5312 7.0311 1.6458 21.0373
NCI-H2373 GDSC1 2.581 6.3335 1.1807 19.8788
NCI-H196 GDSC1; CTRP2 2.5953 13.2766 -1.1667 29.8369
NCI-H1184 CTRP2 2.6264 10.9199 -0.0066 26.5192
NCI-H1869 GDSC1; CTRP2 2.6907 10.9066 0.0621 26.1357
NCI-H1339 CTRP2 2.7196 7.0605 1.832 19.8143
NCI-H322 CTRP2 2.7552 5.9579 2.2949 17.9697
NCI-H1734 GDSC1; CTRP2 2.758 11.1933 -0.0093 26.1821
Calu-6 GDSC1; CTRP2; CTRP1 2.7723 9.5933 0.7599 23.6105
ChaGo-K-1 GDSC1; CTRP2; CTRP1 2.8144 8.323 1.3838 21.2459
NCI-H292 GDSC1; CTRP2 2.9177 6.5717 2.2389 17.7206
Sq-1 CTRP2; CTRP1 2.9435 10.7901 0.362 24.5152
NCI-H2795 GDSC1 2.9555 7.2754 1.0534 19.1563
SHP-77 GDSC1; CTRP2; CTRP1 2.9595 8.562 1.422 20.7213
NCI-H1373 CTRP2; CTRP1 3.0242 6.695 2.3021 17.1854
DMS 53 GDSC1; CTRP2 3.0317 6.3272 2.4557 16.5782
NCI-H1838 GDSC1; CTRP2 3.1553 10.7498 0.5844 23.2315
Lu-165 GDSC1 3.1572 17.3661 -3.8154 36.1192
NCI-H2405 GDSC1; CTRP2; CTRP1 3.2654 8.922 1.5595 19.4174
NCI-H513 GDSC1 3.313 13.2954 -1.6495 30.5466
NCI-H2228 GDSC1; CTRP2 3.3921 8.9657 1.6632 18.7033
COR-L105 GDSC1; CTRP2 3.4033 6.3095 2.8578 14.0097
HCC15 GDSC1; CTRP2; CTRP1 3.5061 9.1907 1.6674 18.4059
NCI-H2731 GDSC1 3.5276 7.9526 1.1992 15.9685
NCI-H2029 GDSC1; CTRP2; CTRP1 3.5382 13.1502 -0.2273 24.91
HCC33 GDSC1; CTRP1 3.5441 21.1854 -4.2055 40.2739
HCC1171 CTRP2 3.5621 12.7244 0.004 24.14
Calu-3 GDSC1; CTRP2; CTRP1 3.609 6.2486 3.0999 12.5134
NCI-H2106 CTRP2 3.6115 10.2123 1.2772 19.6322
NCI-H1092 GDSC1; CTRP2 3.7012 12.6287 0.1785 23.2555
NCI-H290 GDSC1 3.761 7.4254 1.6483 11.938
SW1573 GDSC1; CTRP2 3.827 24.0239 -5.3733 34.6652
HCC95 CTRP2 3.8348 9.7024 1.735 17.3556
RERF-LC-Sq1 GDSC1 3.8648 19.2353 -4.1637 34.7955
PC-14 GDSC1; CTRP2 3.9181 7.7281 2.7603 13.0637
SW1271 GDSC1; CTRP2 4.0132 11.7628 0.8893 20.1117
NCI-H2804 GDSC1 4.0606 7.5872 1.7951 9.8945
NCI-H1781 GDSC1; CTRP1 4.085 6.0292 3.6908 13.6329
NCI-H1436 GDSC1 4.1035 15.2032 -1.9566 28.9798
NCI-H1563 GDSC1; CTRP2 4.1208 10.4552 1.6319 17.097
NCI-H345 GDSC1 4.1328 12.9652 -0.8174 24.8445
Calu-1 CTRP2 4.153 11.53 1.1307 18.9193
NCI-H650 GDSC1; CTRP2; CTRP1 4.184 14.8612 -0.4955 24.229
IA-LM GDSC1; CTRP2 4.2644 11.1662 1.411 17.6225
NCI-H727 GDSC1; CTRP2; CTRP1 4.5251 10.6093 1.92 15.0762
NCI-H1688 GDSC1 4.5623 15.2305 -1.6083 26.5064
NCI-H2369 GDSC1 4.6359 6.2908 2.7682 1.5807
LOU-NH91 GDSC1; CTRP2 4.6439 9.9075 2.374 12.9952
HCC1195 CTRP2; CTRP1 4.6579 12.8494 0.9207 18.5819
NCI-H2595 GDSC1 4.6844 8.7189 1.6846 8.9351
NCI-H889 CTRP2 4.7113 12.9462 0.9185 18.4769
NCI-H2722 GDSC1 4.753 7.7661 2.178 5.2667
NCI-H1435 GDSC1; CTRP2; CTRP1 4.7732 7.9291 3.4709 8.1805
A-549 GDSC1; CTRP2; CTRP1 4.8192 8.4612 3.2479 9.0128
RERF-LC-Ad2 CTRP2 4.9603 17.8678 -1.3285 24.8843
NCI-H2291 GDSC1; CTRP2 4.9755 13.4289 0.9032 17.9834
NCI-H2869 GDSC1 4.979 11.7372 0.4291 16.1817
NCI-H2444 GDSC1; CTRP2 5.0402 9.0586 3.1421 9.002
NCI-H838 GDSC1; CTRP2 5.0761 7.2022 4.0998 4.919
NCI-H2461 GDSC1 5.0973 7.3048 2.5747 2.0429
NCI-H510A GDSC1; CTRP2 5.11 13.121 1.1705 16.739
NCI-H1770 GDSC1 5.1919 6.5527 2.9111 0.3896
NCI-H720 GDSC1 5.2033 6.6133 2.8935 0.4388
NCI-H1915 GDSC1; CTRP2; CTRP1 5.2519 13.4812 1.1089 16.6825
HCC1588 CTRP2 5.287 14.923 0.4172 19.0434
NCI-H2126 CTRP2; CTRP1 5.3227 8.2833 3.7659 5.842
NCI-H2803 GDSC1 5.3244 7.4594 2.6206 1.5046
A-427 GDSC1 5.3728 10.2685 1.4013 9.1517
LC-1/sq GDSC1 5.5395 7.767 2.5962 1.3909
NCI-H441 GDSC1; CTRP2; CTRP1 5.5408 10.4484 2.8607 9.2193
NCI-H2818 GDSC1 5.5927 8.8182 2.1868 3.6004
Lu-99A GDSC1 5.6003 14.7119 -0.5775 19.5709
NCI-H460 GDSC1; CTRP2; CTRP1 5.611 6.7301 4.7522 1.2689
NCI-H2023 GDSC1; CTRP2; CTRP1 5.6342 8.3291 3.9879 4.3627
NCI-H226 GDSC1; CTRP2 5.7213 7.3973 4.5071 2.0946
LXF 289 GDSC1; CTRP2; CTRP1 5.7313 10.985 2.7442 9.3568
NCI-H2342 GDSC1; CTRP2; CTRP1 5.7779 12.2402 2.1559 11.6608
NCI-H2591 GDSC1 5.868 8.1955 2.5736 1.1811
DV-90 CTRP2; CTRP1 5.9662 12.5999 2.1244 11.4505
NCI-H1299 GDSC1; CTRP2; CTRP1 6.1554 16.6374 0.2634 17.9065
COR-L88 GDSC1; CTRP1 6.195 15.5663 0.8277 22.0087
NCI-H2172 GDSC1; CTRP2; CTRP1 6.2178 10.5704 3.3158 6.1964
LC-1/sq-SF CTRP2; CTRP1 6.4638 8.2364 4.5692 1.0282
NCI-H1650 GDSC1; CTRP2 6.5005 11.2598 3.1809 6.3145
SBC-5 GDSC1; CTRP2 6.5587 7.7816 4.7996 0.3141
MOR/CPR CTRP2 6.6218 7.5823 4.8979 0.1127
DMS 79 GDSC1; CTRP2 6.9185 14.2842 2.0056 10.3355
NCI-H1623 GDSC1; CTRP2 7.3501 13.0615 2.892 6.2663
RERF-LC-A1 CTRP2 7.7414 26.0411 -3.1788 24.2677
HCC2279 CTRP2 7.9406 18.3578 0.7489 13.328
RERF-LC-Ad1 CTRP2 8.6039 24.7937 -1.918 20.1059
NCI-H1651 GDSC1; CTRP2 8.994 17.6814 1.7745 8.3199
Hs 888.Lu CTRP2 2.0598 7.1015 1.1189 24.3062
⏷ Show the Full List of 217 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 -4.4316 4.702 -5.5452 70.0641
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 -1.0423 9.6783 -3.1973 44.5639
Aska-SS CTRP2 0.3305 10.2795 -2.021 38.2314
Rh41 GDSC1; CTRP2 -3.1591 1.3102 -3.2246 55.3696
G-401 GDSC1; CTRP2; CTRP1 -1.5841 6.8191 -2.6991 46.3661
RKN GDSC1; CTRP2; CTRP1 -1.5122 4.8021 -2.0189 45.4277
Rh30 GDSC1 -1.4298 5.9274 -2.7401 55.2401
G-402 GDSC1; CTRP2 -1.2813 6.6326 -2.3082 44.6859
A-204 GDSC1; CTRP2 -0.8914 5.2652 -1.4639 41.8185
TE 617.T CTRP2 -0.6459 5.4027 -1.2345 40.3591
KYM-1 GDSC1; CTRP2 -0.3271 5.425 -0.893 38.345
Rh18 CTRP2 -0.281 7.4384 -1.5107 39.4619
SK-LMS-1 GDSC1; CTRP2 0.1575 8.3396 -1.3895 37.6298
RD GDSC1; CTRP2 0.4427 6.3317 -0.3373 34.0982
EW-8 GDSC1 0.678 2.8936 0.5455 34.2679
VA-ES-BJ GDSC1 0.8569 7.0211 -0.8241 38.6792
Hs 633.T GDSC1 1.0438 3.4316 0.8116 30.3608
Hs 729.T CTRP2 1.4808 7.996 0.1457 29.2999
TE 441.T GDSC1; CTRP2 2.3251 4.6281 2.1993 19.6116
SW872 GDSC1 2.915 7.1858 1.0623 19.2624
MES-SA GDSC1; CTRP2 2.9562 7.3525 1.956 18.6987
MFH-ino GDSC1 3.1158 13.123 -1.7289 31.4639
HT-1080 GDSC1; CTRP2; CTRP1 3.5156 10.3909 1.1001 20.5179
SK-UT-1 GDSC1; CTRP2 3.7516 12.3157 0.3786 22.4806
Tm87-16 CTRP2 3.9519 11.5924 0.9177 20.1502
TTC-709 CTRP2 4.0086 16.7784 -1.6039 27.5692
GCT GDSC1; CTRP2 4.6254 10.0308 2.2963 13.3507
SW684 GDSC1 5.1681 11.3261 0.7615 13.7165
BT-16 CTRP2 5.6321 14.0575 1.1325 15.8601
BT-12 CTRP2 6.5487 7.3074 4.9666 0.047
SW982 GDSC1; CTRP2 7.1732 23.8045 -2.5065 23.72
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -0.1771 14.0399 -4.2269 42.6266
RMUG-S CTRP1 -2.5947 8.776 -4.4914 69.0595
A2780 GDSC1; CTRP2; CTRP1 -2.4434 4.599 -2.9839 50.7352
IGROV-1 GDSC1; CTRP2; CTRP1 -1.7465 1.9776 -1.8015 46.3456
OVCAR-8 GDSC1; CTRP2; CTRP1 -1.4417 3.6612 -1.6927 44.6751
COV434 CTRP2; CTRP1 -1.3643 3.5497 -1.5892 44.1474
OC 314 GDSC1; CTRP2 -0.8743 5.2411 -1.4385 41.7003
OVK18 GDSC1; CTRP2; CTRP1 -0.6767 2.9178 -0.7639 39.3959
OV7 CTRP2; CTRP1 -0.2964 10.3245 -2.6884 41.3519
FU-OV-1 GDSC1; CTRP2 -0.01 6.3481 -0.8338 37.0064
OVKATE GDSC1; CTRP1 0.0233 3.8574 -0.1468 52.3374
COV362 CTRP2; CTRP1 0.331 10.7758 -2.2378 56.8963
RMG-I GDSC1; CTRP2; CTRP1 0.4618 6.7887 -0.4751 34.4092
MCAS CTRP2 0.4883 4.2776 0.2783 32.086
SK-OV-3 GDSC1; CTRP2; CTRP1 0.6739 5.693 0.1196 31.9633
TOV-21G GDSC1 0.7765 6.2849 -0.5754 38.4067
OAW28 GDSC1; CTRP2 0.8389 8.3698 -0.6826 33.6873
OVCAR-4 GDSC1; CTRP2; CTRP1 0.9255 4.9942 0.5912 29.6125
COV644 CTRP2; CTRP1 1.0952 4.1756 0.9536 27.8382
OVTOKO GDSC1; CTRP2 1.2552 8.1161 -0.1408 30.8634
JHOM-1 CTRP2; CTRP1 1.4778 3.8453 1.4123 25.0364
OVMANA CTRP1 1.4837 11.5534 -1.4266 51.1741
EFO-27 GDSC1; CTRP2; CTRP1 1.5529 7.5447 0.4054 28.2527
ONCO-DG-1 CTRP2 1.605 7.7552 0.3751 28.1938
OV56 GDSC1; CTRP2 1.6548 4.6886 1.459 24.3099
JHOC-5 CTRP2; CTRP1 1.763 4.4378 1.6274 23.3816
ES-2 GDSC1 1.8391 6.3207 0.4762 27.8378
COV318 CTRP1 2.1391 9.4304 0.2017 47.0355
HEY A8 CTRP2; CTRP1 2.2732 7.4221 1.2143 23.3522
TOV-112D GDSC1; CTRP2 2.4871 10.8628 -0.1153 27.2227
SNU-119 CTRP2 2.5275 6.8413 1.7181 20.7776
JHOS-2 GDSC1; CTRP2 2.6885 8.3242 1.2554 22.0574
SNU-8 CTRP2 2.6923 8.7211 1.0808 22.6833
TYK-nu GDSC1; CTRP2; CTRP1 2.7199 7.8801 1.4836 21.1266
OAW42 GDSC1; CTRP2; CTRP1 2.7402 5.9725 2.2735 18.0929
SNU-840 CTRP2; CTRP1 3.4541 6.6813 2.7589 14.2542
Caov-4 GDSC1 3.6282 13.3033 -1.3926 28.651
JHOS-4 CTRP1 3.6797 6.1325 3.2211 25.3441
OVCAR-5 GDSC1; CTRP2 4.244 9.2586 2.3331 14.035
Kuramochi GDSC1; CTRP2 4.249 10.0894 1.9291 15.6444
EFO-21 GDSC1; CTRP2; CTRP1 4.5899 8.3002 3.1216 10.0291
OVCAR-3 GDSC1 5.5721 7.0415 2.8805 0.2988
OVISE GDSC1; CTRP2 6.0967 14.1854 1.4377 13.8745
OV-90 GDSC1; CTRP2; CTRP1 6.2739 10.6694 3.3077 6.1429
Caov-3 GDSC1; CTRP2; CTRP1 6.8276 12.6839 2.7198 7.6752
ES2 CTRP2 7.0122 8.089 4.8636 0.0813
DOV13 GDSC1; CTRP2 7.2747 9.104 4.5982 0.445
OVSAHO CTRP2 7.451 17.1963 0.9659 13.3291
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.5794 12.5412 0.11 23.7633
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 5.4436 11.7658 2.1243 12.4056
P-STS CTRP2 6.94 13.7984 2.2578 9.3248
SYO-1 CTRP2 8.5772 23.381 -1.2454 18.417
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; CTRP2; CTRP1 -1.358 4.8084 -1.8524 44.4984
IST-Mes1 GDSC1; CTRP2 2.4348 9.3491 0.5363 25.281
NCI-H28 GDSC1; CTRP1 2.7702 7.5072 1.6969 30.1816
MPP 89 GDSC1; CTRP2 3.2006 7.2709 2.2437 16.936
ACC-MESO-1 CTRP2 3.579 9.2967 1.6872 18.1519
NCI-H2452 GDSC1; CTRP2 5.0979 6.8698 4.2846 4.101
NCI-H2052 GDSC1; CTRP2; CTRP1 6.6581 11.5169 3.1662 6.1427
JL-1 CTRP2 7.7566 9.1776 4.7549 0.083
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; CTRP2 -1.7707 2.2888 -1.8533 46.5397
PC-3 GDSC1 -1.7066 7.626 -3.7221 55.8061
LNCaP clone FGC GDSC1; CTRP2 -0.8655 2.6509 -0.9358 40.5952
NCI-H660 CTRP2 -0.4685 8.1406 -1.9768 40.9661
22Rv1 GDSC1; CTRP2 -0.4505 4.0565 -0.6951 38.3354
PaCa-3 CTRP2; CTRP1 0.2053 6.0541 -0.5038 35.3879
DU145 GDSC1; CTRP2 3.3762 12.3246 0.0284 24.51
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; CTRP2 2.898 9.3558 0.9947 22.4509
YD-15 CTRP2 8.0004 15.6817 2.0767 8.498
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 -2.7282 0.6961 -2.7898 71.4441
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC1; CTRP2 -3.1049 1.7349 -3.2037 54.9458
RF-48 GDSC1 -2.8752 8.2164 -5.1907 60.362
SNU-216 CTRP2 -1.9277 3.1262 -2.1255 47.6483
NCC-StC-K140 CTRP2 -1.6382 1.1051 -1.6486 45.5593
Hs 746.T GDSC1; CTRP2 -0.9437 5.4881 -1.5838 42.2489
SNU-1 GDSC1; CTRP2 -0.7297 6.6624 -1.72 41.58
HSC-39 GDSC1 0.1806 9.4726 -2.6303 45.4712
GSS CTRP2 0.3896 3.6038 0.2849 32.3972
23132/87 GDSC1; CTRP2 0.552 7.1306 -0.5024 34.1726
ECC10 GDSC1; CTRP2 1.5811 11.0481 -1.0965 32.4329
RERF-GC-1B GDSC1 1.7367 8.6295 -0.7275 33.7729
GCIY GDSC1 1.8407 6.439 0.4223 28.1277
LMSU CTRP2 2.0863 10.7312 -0.4478 29.2918
MKN7 GDSC1; CTRP2; CTRP1 2.2533 8.8184 0.5922 25.5939
MKN1 GDSC1; CTRP2 2.3523 10.208 0.0585 27.0542
SNU-601 CTRP2 2.4603 5.9078 1.9932 41.4362
TMK-1 GDSC1 3.0942 6.948 1.3375 16.631
AGS GDSC1; CTRP2; CTRP1 3.1364 10.4648 0.703 22.8706
MKN74 CTRP2; CTRP1 3.7068 12.8971 0.0512 23.6497
IM95 GDSC1; CTRP2 3.7809 6.3127 3.2546 11.4475
SNU-16 GDSC1; CTRP2 4.1694 5.1236 4.0966 7.1686
NUGC-3 GDSC1; CTRP2 4.4475 13.9755 0.1763 21.5803
ECC12 CTRP2 4.7905 10.9046 2.0056 14.1752
HuG1-N CTRP2 5.0595 6.6882 4.3417 3.9405
KATO III CTRP2 5.0684 6.5383 4.4241 3.577
Fu97 GDSC1; CTRP2; CTRP1 5.3854 7.1088 4.4021 3.0632
OCUM-1 GDSC1 5.4763 7.2546 2.7662 0.711
MKN28 GDSC1 5.6319 15.4366 -0.9085 20.9183
SH-10-TC CTRP2; CTRP1 5.6657 6.939 4.689 1.4452
NCI-N87 GDSC1; CTRP2 5.9576 9.5165 3.6432 5.2624
GSU CTRP2 6.0325 6.579 5.0325 0.0594
TGBC11TKB GDSC1 6.0839 7.6767 2.8453 0.2079
SCH GDSC1 6.1765 14.631 -0.1394 16.0654
MKN45 GDSC1; CTRP2 6.2838 7.2248 4.8955 0.2228
SNU-5 GDSC1; CTRP2 6.5014 11.564 3.0339 6.9063
SNU-719 CTRP2 6.8654 9.0159 4.4448 1.1002
SNU-620 CTRP2 7.0355 8.1064 4.8659 0.0756
NUGC-4 GDSC1; CTRP2; CTRP1 7.3409 9.3489 4.5327 0.5631
KE-39 CTRP2 7.497 14.2227 2.4372 7.8215
SNU-668 CTRP2 7.6321 16.2302 1.5642 10.9106
SNU-685 CTRP2 2.679 9.8093 0.5672 24.5193
SNG-M GDSC1; CTRP2; CTRP1 2.7715 7.0883 1.875 19.5087
SNU-1077 CTRP2 4.2312 9.7163 2.0966 15.0167
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1 -3.0073 7.1012 -4.8775 61.874
K5 GDSC1 -1.9172 11.0837 -5.4615 55.1664
HTC-C3 GDSC1 -1.1808 3.6332 -1.6735 54.8374
SW579 CTRP2 -0.2247 6.3246 -1.0591 38.3298
IHH-4 GDSC1 0.4414 13.5574 -4.339 45.6285
8305C GDSC1; CTRP2 1.0003 7.6261 -0.2128 31.8815
CGTH-W-1 GDSC1; CTRP2 1.6088 8.6619 -0.0015 29.3661
FTC-238 CTRP2 1.7561 6.7626 0.9263 25.8798
CAL-62 GDSC1; CTRP2 1.7616 48.6017 -19.4229 45.2886
ML-1 [Human leukemia] GDSC1; CTRP2 3.1276 8.9145 1.427 20.2685
ASH-3 GDSC1 3.3509 8.5961 0.7318 19.6861
FTC-133 GDSC1; CTRP2 3.7643 9.1252 1.9471 16.6908
TT2609-C02 GDSC1; CTRP2 3.9668 11.332 1.0596 19.6025
8505C GDSC1; CTRP2 4.626 11.9383 1.3472 17.0791
WRO GDSC1 6.0201 11.2648 1.3396 8.1137
B-CPAP GDSC1; CTRP2 6.3486 10.1813 3.5969 4.8591
TT GDSC1; CTRP2 7.1735 8.6971 4.7087 0.2638
BHT-101 GDSC1; CTRP2 7.5502 8.908 4.7741 0.092
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHU-011 GDSC1 -2.3452 3.408 -2.8802 63.4042
SCC-9 GDSC1; CTRP2; CTRP1 -1.681 4.3773 -2.1005 46.338
PCI-04B GDSC1 -0.8952 4.9965 -1.816 51.9871
NCI-H3118 GDSC1 -0.8404 5.5396 -1.9618 51.4671
BB30-HNC GDSC1 -0.5638 6.8846 -2.2185 49.47
BICR 56 CTRP2 -0.3717 3.7861 -0.5602 37.672
CAL-33 GDSC1; CTRP2 -0.285 2.6358 -0.327 36.6719
HSC-2 GDSC1; CTRP2; CTRP1 -0.0858 2.7413 -0.1272 35.3474
YD-10B CTRP2 0.032 7.3898 -1.1567 37.5887
SAS GDSC1 0.0489 11.8294 -3.8759 46.9154
BICR 22 GDSC1; CTRP2 0.291 5.2389 -0.1663 34.1386
SNU-1076 CTRP2 0.3601 6.5918 -0.5158 34.8719
BHY GDSC1; CTRP2 0.4634 6.8459 -0.4938 34.4539
PCI-15A GDSC1 0.5561 5.146 -0.3233 38.99
KOSC-2 GDSC1 0.7259 5.9278 -0.4718 38.386
PE/CA-PJ34 (clone C12) CTRP2 0.8135 4.4915 0.5873 29.9909
BICR 18 CTRP2 0.832 3.9933 0.7009 29.5498
Ca9-22 GDSC1 0.9492 9.0534 -1.6829 40.2633
PE/CA-PJ49 CTRP2 1.1177 6.1403 0.459 29.4312
OSC-20 GDSC1 1.222 7.0042 -0.4516 35.4095
CAL-27 GDSC1; CTRP2 1.4382 7.6623 0.2368 29.1438
BICR 31 GDSC1; CTRP2 1.7076 6.8871 0.8272 26.3691
YD-8 CTRP2 1.8264 6.3422 1.1561 24.8596
PE/CA-PJ41 (clone D2) CTRP2 1.8323 9.3838 -0.0883 28.969
SCC-25 GDSC1; CTRP2 1.8923 4.284 1.7935 22.3946
HO-1-u-1 GDSC1 2.1592 7.0633 0.4302 26.5173
BICR 16 CTRP2 2.1614 8.1333 0.7977 25.1485
DOK GDSC1 2.592 7.1101 0.8097 22.2827
OSC-19 GDSC1 2.7958 9.0105 0.0495 25.7215
SAT [Human HNSCC] GDSC1 2.853 7.2568 0.9722 20.1187
SCC-15 GDSC1 3.0029 4.7031 2.3696 9.1613
BICR 6 CTRP2 3.0331 8.2785 1.625 19.7626
PE/CA-PJ15 GDSC1; CTRP2 3.1354 7.7296 1.9752 18.1504
HSC-4 GDSC1; CTRP2 3.1755 7.264 2.2208 17.0914
HO-1-N-1 GDSC1 3.2789 7.3272 1.3059 16.1412
JHU-022 GDSC1 3.3199 11.5687 -0.7804 27.4415
SNU-46 CTRP2 3.4039 16.4316 -1.9692 29.7683
LB771-HNC GDSC1 3.464 5.5535 2.346 7.5824
SCC-4 GDSC1; CTRP2 3.7503 7.0784 2.8912 12.9581
PCI-38 GDSC1 3.7786 11.7235 -0.4809 24.5666
BICR 78 GDSC1 4.2144 12.2406 -0.3926 22.7287
SKN-3 GDSC1 4.7557 11.2201 0.5208 16.2976
PCI-06A GDSC1 4.8882 9.2509 1.567 9.2281
FaDu GDSC1; CTRP2 5.2325 12.6185 1.5241 15.1663
KON GDSC1 5.6751 12.8216 0.3887 14.5491
BICR 10 GDSC1 5.6966 7.3852 2.8054 0.4465
BB49-HNC GDSC1 6.3836 8.505 2.6662 0.5133
SNU-1066 CTRP2 7.085 13.2801 2.61 7.7323
PCI-30 GDSC1 7.5784 22.7149 -3.0703 23.7886
SNU-1214 CTRP2 7.6681 11.1397 3.9559 2.0108
Detroit 562 GDSC1; CTRP2 7.7739 9.5344 4.6379 0.2127
SNU-899 CTRP2 8.4682 17.9204 1.3216 10.5947
HSC-3 GDSC1; CTRP2 8.5416 20.9092 -0.0667 15.077
SNU-1041 CTRP2 8.8105 15.5244 2.6541 5.4063
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1710 GDSC1; CTRP2 -1.8736 7.0949 -3.1067 47.8956
253J CTRP2 -0.5475 4.7562 -0.9556 39.3578
SCaBER CTRP2 0.281 3.873 0.1279 33.2724
UM-UC-3 GDSC1; CTRP2; CTRP1 0.4329 7.7101 -0.8494 35.4651
647V GDSC1; CTRP2 0.8134 8.1957 -0.6384 33.6562
UM-UC-1 CTRP2 0.8313 5.0557 0.4726 30.3128
RT-112 GDSC1; CTRP2 1.3948 4.6649 1.1815 26.0966
JMSU-1 CTRP2 1.9914 7.4733 0.897 25.2901
5637 GDSC1; CTRP2; CTRP1 2.0983 5.0471 1.8571 21.5258
HT-1197 GDSC1; CTRP2 2.1581 8.1171 0.8012 25.1458
VM-CUB-1 CTRP2 2.2236 5.5964 1.8375 21.2161
U-BLC1 CTRP2 2.3852 5.1628 2.1399 19.6358
BC-3C CTRP2 2.6396 10.8673 0.0312 26.3671
J82 GDSC1; CTRP2 2.9609 8.4335 1.4819 20.4927
KMBC-2 CTRP2; CTRP1 3.0961 6.79 2.3389 19.4662
TCCSUP GDSC1; CTRP2 3.9815 8.6103 2.4019 14.3601
T24 GDSC1; CTRP2 4.386 9.9425 2.1259 14.5556
HT-1376 GDSC1; CTRP2; CTRP1 4.6513 9.8344 2.4168 12.8046
CAL-29 GDSC1 5.086 6.5993 2.8514 0.6716
RT-4 GDSC1; CTRP2; CTRP1 5.2621 6.4351 4.6399 2.2902
SW780 GDSC1 5.4127 6.9128 2.8663 0.4098
KU-19-19 GDSC1; CTRP2 6.9025 8.4179 4.7024 0.3779
BFTC-905 GDSC1; CTRP2 6.9854 8.9021 4.5496 0.7118
253J-BV CTRP2 7.2871 8.6332 4.7746 0.1348
639V GDSC1; CTRP2 7.823 14.6197 2.4634 7.2835
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Ca Ski GDSC1 -6.1927 2.329 -6.8033 79.0829
KGN GDSC1 -4.6221 4.9026 -5.8173 70.2884
ME-180 GDSC1 -4.04 4.1082 -4.9328 69.8561
OVMIU GDSC1 -3.627 0.8268 -3.7524 76.0888
BPH-1 GDSC1 -3.3574 1.161 -3.5088 73.8685
PA-1 GDSC1 -3.3231 -0.5634 -3.3353 78.8625
C-33 A GDSC1 -1.2979 6.2719 -2.7359 54.2668
NCC-IT GDSC1 -1.0256 9.2514 -3.7324 51.9235
ACC-OV7 GDSC1 -0.8823 8.8876 -3.4236 51.2567
HEY GDSC1 -0.135 11.0069 -3.6618 47.6156
OV17R GDSC1 0.2077 16.7551 -6.1193 47.2407
OMC-1 [Human cervical carcinoma] GDSC1 0.304 5.1729 -0.6011 41.561
NT2-D1 GDSC1 1.0741 8.504 -1.3008 38.7718
DSH1 GDSC1 1.302 4.7037 0.6429 29.8198
SiSo GDSC1 1.5097 9.5759 -1.4006 36.9143
SW954 GDSC1 1.5147 4.2543 1.0456 26.1127
JAR GDSC1 1.5439 6.6991 0.0088 31.763
SKN GDSC1 1.8771 11.7201 -2.1145 37.0779
OVCA433 GDSC1 2.1744 11.1565 -1.5679 34.5064
LB831-BLC GDSC1 2.2485 11.0402 -1.4439 33.8492
UWB1.289 GDSC1 2.2793 7.9174 0.1259 27.5736
JHOS-3 GDSC1 2.5996 8.1941 0.281 25.3403
CAL-39 GDSC1 3.7573 8.3492 1.1856 15.2552
SW962 GDSC1 3.9454 9.4593 0.7806 17.2691
HEC-1 GDSC1 4.1381 6.9956 2.1397 7.086
NEC8 GDSC1 4.2714 10.3041 0.6124 17.2332
HT-3 GDSC1 4.6232 12.1491 -0.0342 19.7161
DoTc2 4510 GDSC1 4.9058 11.3703 0.5557 15.6621
C-4-I GDSC1 5.2093 7.0139 2.7449 1.0225
SiHa GDSC1 5.4242 6.6637 2.958 0.1781
OVCA420 GDSC1 5.4402 7.3046 2.7324 0.8727
MS751 GDSC1 5.5075 7.1556 2.8152 0.518
SW756 GDSC1 5.6282 11.5713 0.9527 11.3837
JEG-3 GDSC1 5.7398 7.0891 2.9242 0.1567
SKG-IIIa GDSC1 5.837 7.5488 2.8002 0.395
PEO1 GDSC1 6.1206 8.0792 2.7185 0.4902
HeLa GDSC1; CTRP2 7.0204 7.9827 4.9024 0.0462
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

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6 PI-103 and sorafenib inhibit hepatocellular carcinoma cell proliferation by blocking Ras/Raf/MAPK and PI3K/AKT/mTOR pathways. Anticancer Res. 2010 Dec;30(12):4951-8.