Details of the Drug

General Information of Drug (ID: DMELPJM)

Drug Name

EDD7H9

Synonyms

Anti S1P3 antibody (breast cancer), Expression Drug Designs; Anti-GPCR Abs (cancer), Expression Drug Designs; G-protein-coupled receptor inhibitor antibodies (breast cancer), Expression Drug Designs

Indication

Disease Entry	ICD 11	Status	REF
Breast cancer	2C60-2C65	Preclinical	[1]

Drug Type

Antibody

Cross-matching ID

TTD ID: D0Q2HM

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Sphingosine-1-phosphate receptor 3 (S1PR3)	TTDYP7I	S1PR3_HUMAN	Not Available	[2]

Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Opportunities for therapeutic antibodies directed at G-protein-coupled receptors. Nat Rev Drug Discov. 2017 Sep;16(9):787-810.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 277).