Details of the Drug

General Information of Drug (ID: DMETWAU)

Drug Name

Hyaluronidase (ovine)

Synonyms

Hyaluronidase; Hydase; Vitragan; Vitrase; Hyaluronidase Injection; Hyaluronidase (vitreous hemorrhage), ISTA

Indication

Disease Entry	ICD 11	Status	REF
Resorption of radiopaque agents	N.A.	Approved	[1]
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Affected Organisms

Humans and other mammals

ATC Code

B06AA03: Hyaluronidase (ovine)

B06AA: Enzymes

B06A: OTHER HEMATOLOGICAL AGENTS

B06: OTHER HEMATOLOGICAL AGENTS

B: BLOOD AND BLOOD FORMING ORGANS

Sequence

MWTGLGPAVTLALVLVVAWATELKPTAPPIFTGRPFVVAWDVPTQDCGPRHKMPLDPKDM
KAFDVQASPNEGFVNQNITIFYRDRLGMYPHFNSVGGSVHGGVPQNGSLWVHLEMLKGHV
EHYIRTQEPAGLAVIDWEDWRPVWVRNWQDKDVYRRLSRQLVASHHPDWPPERIVKEAQY
EFEFAARQFMLETLRFVKAFRPRHLWGFYLFPDCYNHDYVQNWETYTGRCPDVEVSRNDQ
LSWLWAESTALFPSVYLEETLASSTHGRNFVSFRVQEALRVADVHHANHALPVYVFTRPT
YSRGLTGLSEMDLISTIGESAALGAAGVILWGDAGFTTSNETCRRLKDYLTRSLVPYVVN
VSWAAQYCSWAQCHGHGRCVRRDPNAHTFLHLSASSFRLVPSHAPDEPRLRPEGELSWAD
RNHLQTHFRCQCYLGWGGEQCQWDRRRAAGGASGAWAGFHLTGLLAVAVLAFTWTS

Cross-matching ID

UNII: 8KOG53Z5EM
DrugBank ID: DB14740
TTD ID: D04GPZ

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hyaluronic acid (HA)	TTYTVXF	NOUNIPROTAC	Modulator	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	2005 approvals: Safety first. Nature Reviews Drug Discovery 5, 92-93 (February 2006).
2	Safety results of two phase III trials of an intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage. Am J Ophthalmol. 2005 Oct;140(4):585-97.