Details of the Drug

General Information of Drug (ID: DMEU5ST)

• Drug Name: US8598210, Table XV, 5
• Synonyms: US8722895, 5: [(3-Hydroxy-4'-methyl-biphenyl-4- carbonyl)-amino]-acetic acid; SCHEMBL1921403; CHEMBL3646216; BDBM107699; US8598210, Table XV, 5
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 285.29
  Logarithm of the Partition Coefficient (xlogp); 2.9
  Rotatable Bond Count (rotbonds); 4
  Hydrogen Bond Donor Count (hbonddonor); 3
  Hydrogen Bond Acceptor Count (hbondacc); 4
• Chemical Identifiers:
  Formula: C16H15NO4
  IUPAC Name: 2-[[2-hydroxy-4-(4-methylphenyl)benzoyl]amino]acetic acid
  Canonical SMILES: CC1=CC=C(C=C1)C2=CC(=C(C=C2)C(=O)NCC(=O)O)O
  InChI: InChI=1S/C16H15NO4/c1-10-2-4-11(5-3-10)12-6-7-13(14(18)8-12)16(21)17-9-15(19)20/h2-8,18H,9H2,1H3,(H,17,21)(H,19,20)
  InChIKey: POKDHYRFSOQLCV-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 24891042
  TTD ID: D00XHH

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
HIF-prolyl hydroxylase 2 (HPH-2)	TT9ISBX	EGLN1_HUMAN	Inhibitor	[1]

References

• [1] Prolyl hydroxylase inhibitors and method of use. US8722895.