Details of the Drug

General Information of Drug (ID: DMEYKXL)

Drug Name
NSC-87877
Synonyms CHEMBL472004
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 459.5
Logarithm of the Partition Coefficient (xlogp) 2.4
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 10
Chemical Identifiers
Formula
C19H13N3O7S2
IUPAC Name
8-hydroxy-7-[(6-sulfonaphthalen-2-yl)diazenyl]quinoline-5-sulfonic acid
Canonical SMILES
C1=CC2=C(C=C(C(=C2N=C1)O)N=NC3=CC4=C(C=C3)C=C(C=C4)S(=O)(=O)O)S(=O)(=O)O
InChI
InChI=1S/C19H13N3O7S2/c23-19-16(10-17(31(27,28)29)15-2-1-7-20-18(15)19)22-21-13-5-3-12-9-14(30(24,25)26)6-4-11(12)8-13/h1-10,23H,(H,24,25,26)(H,27,28,29)
InChIKey
XGMFVZOKHBRUTL-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
92577
ChEBI ID
CHEBI:95064
CAS Number
56990-57-9
TTD ID
D00MFW

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Protein-tyrosine phosphatase SHP-1 (PTPN6) TT369M5 PTN6_HUMAN Inhibitor [2]
Protein-tyrosine phosphatase SHP-2 (PTPN11) TT7WUAV PTN11_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Post-Translational Modifications [3]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Post-Translational Modifications [3]
Paxillin (PXN) OTVMMUOF PAXI_HUMAN Post-Translational Modifications [4]
Signal transducer and activator of transcription 3 (STAT3) OTAAGKYZ STAT3_HUMAN Post-Translational Modifications [5]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.4178 6.5002 2.2368 16.0804
EW-13 GDSC1 2.2443 7.6345 0.5714 31.8355
G-292 clone A141B1 GDSC1 2.9992 13.0461 -1.3819 35.0185
ES1 GDSC1 3.5211 4.7543 3.1752 8.4763
EW-1 GDSC1 3.8067 6.1326 2.7686 10.4269
MHH-ES-1 GDSC1 4.7263 6.4071 3.3345 3.1276
EW-24 GDSC1 4.8585 6.7963 3.2361 3.5328
SK-PN-DW GDSC1 5.1074 8.4175 2.6321 7.3311
U2OS GDSC1 5.1601 7.3718 3.1547 3.4523
ES7 GDSC1 5.2259 12.6804 0.6343 19.7149
A-673 GDSC1 5.3629 8.5142 2.7524 5.8342
CAL-72 GDSC1 5.5494 9.1322 2.5816 6.6045
EW-11 GDSC1 5.7097 9.5427 2.4909 6.865
NOS-1 [Human HNSCC] GDSC1 5.9293 8.0091 3.2842 1.4484
HOS GDSC1 5.986 7.2453 3.5938 0.2207
EW-3 GDSC1 6.0709 8.2408 3.2566 1.4297
TC-71 GDSC1 6.1565 7.7788 3.4686 0.4844
SaOS-2 GDSC1 6.1581 8.5906 3.1565 1.8405
ES8 GDSC1 6.1825 7.7775 3.4791 0.438
CAL-78 GDSC1 6.202 8.0023 3.4047 0.6742
SK-ES-1 GDSC1 6.2479 7.8316 3.4846 0.3899
CHSA8926 GDSC1 6.3074 8.0292 3.4365 0.5024
MG-63 GDSC1 6.3302 7.6941 3.5625 0.1796
SJSA-1 GDSC1 6.4349 8.0049 3.493 0.2911
EW-7 GDSC1 6.4753 8.2891 3.4075 0.5019
ES4 GDSC1 6.5167 9.0353 3.1434 1.5105
CHSA0011 GDSC1 6.678 9.1474 3.1703 1.2391
EW-18 GDSC1 6.7392 9.085 3.2197 0.9877
EW-16 GDSC1 6.7495 9.0085 3.2525 0.8565
NY GDSC1 6.7684 8.8669 3.312 0.6402
ES6 GDSC1 6.7911 9.0196 3.2651 0.7839
H-EMC-SS GDSC1 6.8228 9.8079 2.9758 1.9974
HuO9 GDSC1 7.0979 8.9451 3.4068 0.2605
ES5 GDSC1 7.1607 10.1109 3.007 1.5189
CHSA0108 GDSC1 7.2873 9.1639 3.3989 0.2251
HuO-3N1 GDSC1 7.3168 9.327 3.3537 0.3006
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 149 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 6.5706 13.1409 1.3532 12.1197
697 GDSC1 4.15 5.8213 3.2111 5.6994
Ku812 GDSC1 4.2561 11.584 0.4192 23.9593
Karpas-231 GDSC1 4.3538 9.1971 1.6901 16.3603
IM-9 GDSC1 4.4875 6.9582 2.9049 7.0161
KE-37 GDSC1 4.6037 6.1691 3.3679 3.176
SU-DHL-10 GDSC1 4.6495 15.0064 -0.9718 28.1956
WIL2 NS GDSC1 4.8698 6.956 3.1687 3.9932
RPMI-8866 GDSC1 4.9227 9.0814 2.1812 11.1173
OCI-AML-5 GDSC1 4.9351 8.6408 2.4052 9.4629
SUP-M2 GDSC1 4.9427 9.045 2.2134 10.8279
OCI-AML-3 GDSC1 4.958 7.7872 2.833 6.2424
SU-DHL-5 GDSC1 5.0215 6.2824 3.5558 1.118
P32/ISH GDSC1 5.0665 6.7342 3.3861 2.0816
SCC-3 GDSC1 5.0702 8.0025 2.8049 6.1622
JSC-1 GDSC1 5.085 7.7743 2.9223 5.2704
Hs 445 GDSC1 5.0947 7.504 3.0545 4.2962
HL-60 GDSC1 5.1357 6.9989 3.3078 2.4668
HAL-01 GDSC1 5.1492 7.1081 3.267 2.7117
RPMI-8402 GDSC1 5.16 7.6119 3.0449 4.2194
SU-DHL-1 GDSC1 5.1777 6.4659 3.5556 0.9225
DoHH2 GDSC1 5.2015 6.8624 3.4026 1.7545
OCI-AML-2 GDSC1 5.2269 11.1824 1.3729 15.5692
WSU-DLCL2 GDSC1 5.25 8.8194 2.5355 7.6618
DEL GDSC1 5.2568 7.5639 3.1244 3.4632
EHEB GDSC1 5.3133 7.9683 2.9741 4.3832
NK-92MI GDSC1 5.3279 12.9528 0.5763 19.7029
L-363 GDSC1 5.3384 6.7004 3.5355 0.8465
KY821 GDSC1 5.343 7.3868 3.2515 2.4632
HEL GDSC1 5.3667 10.5538 1.7804 12.5788
A3/Kawakami GDSC1 5.3757 6.3402 3.6863 0.2339
P31/FUJ GDSC1 5.3819 9.253 2.4166 8.1732
OCI-M1 GDSC1 5.3873 7.1676 3.3684 1.6804
EJM GDSC1 5.3965 8.442 2.8068 5.373
SU-DHL-16 GDSC1 5.4029 8.3474 2.8544 5.0247
H9 GDSC1 5.4121 9.159 2.481 7.6417
CTV-1 GDSC1 5.4256 8.2603 2.9081 4.6027
ATN-1 GDSC1 5.4526 7.508 3.2575 2.2444
MC116 GDSC1 5.4628 6.5696 3.6372 0.3359
HC-1 GDSC1 5.4675 7.8807 3.1031 3.2017
BL-41 GDSC1 5.4791 7.4497 3.296 1.9707
JVM-3 GDSC1 5.4792 8.1167 3.0046 3.8342
BC-3 GDSC1 5.4803 7.305 3.3573 1.614
KCL-22 GDSC1 5.4916 8.0862 3.0254 3.6707
NU-DUL-1 GDSC1 5.5009 7.3914 3.3315 1.7321
ST486 GDSC1 5.5011 7.4414 3.3107 1.852
Daudi GDSC1 5.5027 7.2696 3.3828 1.4426
JJN-3 GDSC1 5.5085 7.4822 3.2973 1.92
SR GDSC1 5.5173 7.5191 3.2862 1.972
Ramos.2G6.4C10 GDSC1 5.5293 8.9417 2.6575 6.12
MV4-11 GDSC1 5.5554 8.2389 2.9935 3.7606
DND-41 GDSC1 5.5564 7.8839 3.1504 2.7404
MHH-PREB-1 GDSC1 5.5604 7.8972 3.1468 2.7564
NB4 GDSC1 5.5708 6.7684 3.6072 0.3714
ML-2 GDSC1 5.5852 7.7929 3.2048 2.3563
L-428 GDSC1 5.5981 7.9915 3.1261 2.8231
LP-1 GDSC1 5.5987 12.9387 0.7829 17.8409
RL GDSC1 5.6003 7.1142 3.4895 0.8052
Karpas-45 GDSC1 5.6021 7.4519 3.3559 1.4624
JVM-2 GDSC1 5.6024 8.5431 2.8841 4.4021
CTB-1 GDSC1 5.61 8.6087 2.8589 4.5574
Karpas-422 GDSC1 5.6121 7.3625 3.3968 1.2361
NALM-6 GDSC1 5.6212 7.6148 3.2981 1.7562
AMO1 GDSC1 5.632 6.9838 3.5522 0.5237
SK-MM-2 GDSC1 5.6325 9.6837 2.3762 7.8364
P12-Ichikawa GDSC1 5.6378 7.1538 3.4903 0.768
KMS-12-BM GDSC1 5.6767 7.5894 3.3354 1.4802
SU-DHL-4 GDSC1 5.6906 7.0856 3.5381 0.5352
GA-10 GDSC1 5.7038 7.222 3.4923 0.7041
Sc-1 GDSC1 5.7515 7.4462 3.4266 0.947
KG-1 GDSC1 5.7592 9.2932 2.6361 5.7616
PF-382 GDSC1 5.7715 8.3697 3.0551 2.9783
HT GDSC1 5.7787 7.4784 3.426 0.9243
Raji GDSC1 5.7928 7.242 3.5214 0.5269
KMOE-2 GDSC1 5.8012 7.966 3.2409 1.8349
RC-K8 GDSC1 5.8024 7.6385 3.3738 1.1432
RPMI-8226 GDSC1 5.8062 7.7507 3.3309 1.351
THP-1 GDSC1 5.807 7.627 3.3804 1.1072
Farage GDSC1 5.8259 7.5288 3.4269 0.8775
BV-173 GDSC1 5.8417 7.98 3.2547 1.7072
ALL-SIL GDSC1 5.8662 7.4729 3.4652 0.6857
DB GDSC1 5.8745 7.6667 3.3947 0.9757
MOLT-16 GDSC1 5.8797 7.64 3.4072 0.9155
MN-60 GDSC1 5.8813 7.7836 3.352 1.1666
EoL-1 GDSC1 5.8813 8.4919 3.0604 2.7691
WSU-NHL GDSC1 5.8908 7.4522 3.483 0.6002
L-1236 GDSC1 5.8973 8.8788 2.9014 3.7331
OPM-2 GDSC1 5.9039 7.5416 3.4549 0.6976
MOLP-8 GDSC1 5.9189 7.7741 3.3723 1.035
SU-DHL-8 GDSC1 5.9301 7.5211 3.4733 0.6087
Namalwa GDSC1 5.9397 7.5641 3.4612 0.6472
Karpas-299 GDSC1 5.9409 8.2469 3.1931 1.916
A4/Fukuda GDSC1 5.9494 7.7973 3.3766 0.9872
U266B1 GDSC1 5.9538 7.8335 3.3645 1.0375
SUP-HD1 GDSC1 5.9539 8.6471 3.0318 2.8285
Reh GDSC1 5.9606 7.6669 3.4312 0.7479
TUR GDSC1 5.965 8.031 3.2918 1.3706
SUP-T1 GDSC1 5.9739 7.8682 3.3598 1.0398
QIMR-WIL GDSC1 5.9793 9.2315 2.7915 4.2917
HDLM-2 GDSC1 5.9912 8.6615 3.0449 2.6933
NOMO-1 GDSC1 5.9992 7.3309 3.5688 0.2748
KM-H2 GDSC1 5.9995 8.0591 3.2963 1.3116
ME1 GDSC1 6.0042 7.0459 3.668 0.0858
JURL-MK1 GDSC1 6.0183 8.0532 3.3071 1.2404
Granta-519 GDSC1 6.0184 8.0104 3.3239 1.1613
EM-2 GDSC1 6.021 7.564 3.4937 0.4805
MOLT-4 GDSC1 6.0239 7.4864 3.5229 0.3885
Karpas-620 GDSC1 6.0362 7.3904 3.5616 0.278
CESS GDSC1 6.0382 7.5566 3.5031 0.441
TK [Human B-cell lymphoma] GDSC1 6.0812 7.7572 3.4468 0.6032
Jiyoye GDSC1 6.082 8.0154 3.3497 0.9866
LC4-1 GDSC1 6.1169 8.2238 3.284 1.2503
DG-75 GDSC1 6.1389 8.4287 3.2128 1.573
U-698-M GDSC1 6.1773 8.206 3.3173 1.043
BE-13 GDSC1 6.1847 8.0801 3.3685 0.8243
CCRF-CEM GDSC1 6.1857 7.7981 3.4729 0.4551
OCI-Ly19 GDSC1 6.2205 8.2078 3.3351 0.9311
CA46 GDSC1 6.2229 8.2307 3.3273 0.9612
LAMA-84 GDSC1 6.2367 9.4309 2.8441 3.5183
VAL GDSC1 6.2746 8.4582 3.262 1.1991
P30/OHK GDSC1 6.3315 8.0138 3.4513 0.4449
RPMI-6666 GDSC1 6.3594 7.9527 3.4835 0.3435
K-562 GDSC1 6.3658 12.6932 1.4316 12.149
L-540 GDSC1 6.3798 7.7515 3.5604 0.1706
MLMA GDSC1 6.4302 8.218 3.4157 0.5006
KOPN-8 GDSC1 6.4409 7.9906 3.5001 0.2726
NKM-1 GDSC1 6.4553 8.5954 3.2865 0.9412
MEG-01 GDSC1 6.4728 8.593 3.2947 0.8956
HH [Human lymphoma] GDSC1 6.4746 8.684 3.261 1.0292
SUP-B15 GDSC1 6.4953 8.0869 3.4864 0.2844
ARH-77 GDSC1 6.5196 8.1628 3.4689 0.3163
RS4;11 GDSC1 6.5312 8.2034 3.4589 0.3359
GR-ST GDSC1 6.5357 8.8068 3.24 1.0656
MY-M12 GDSC1 6.5392 8.6498 3.3006 0.8248
YT GDSC1 6.5414 8.3416 3.4139 0.4504
BC-1 GDSC1 6.5827 8.1041 3.5118 0.2052
BALL-1 GDSC1 6.6157 7.985 3.5634 0.1163
Kasumi-1 GDSC1 6.7876 8.4359 3.471 0.2254
ALL-PO GDSC1 6.7956 8.9465 3.2937 0.684
Loucy GDSC1 6.818 8.4044 3.4923 0.1803
SU-DHL-6 GDSC1 6.8975 8.3294 3.5445 0.0949
VL51 GDSC1 6.9111 8.871 3.3648 0.4185
ROS-50 GDSC1 6.9212 9.0766 3.2954 0.6086
MOLM-13 GDSC1 6.9281 8.6702 3.4406 0.2437
EB2 GDSC1 6.9762 8.32 3.5737 0.0586
PL-21 GDSC1 7.1275 9.1351 3.3519 0.3666
GDM-1 GDSC1 7.1385 8.9208 3.4293 0.2094
Mono-Mac-6 GDSC1 7.9442 10.1872 3.2817 0.265
SIG-M5 GDSC1 8.1982 19.5226 -0.6033 17.8436
⏷ Show the Full List of 149 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC1 3.6939 8.7826 1.3491 21.0164
HCE-4 GDSC1 3.8812 5.8856 2.9564 8.669
KYSE-220 GDSC1 5.8459 8.5481 3.0176 3.0884
TE-12 GDSC1 7.0548 9.5057 3.1913 0.8729
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 6.2215 9.5598 2.7803 3.9359
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-17 GDSC1 1.0831 3.6509 0.9048 37.4311
SJNB-6 GDSC1 3.5167 7.4362 1.8642 18.3529
SK-N-MC-IXC GDSC1 5.0184 6.2056 3.5859 0.9548
Kelly GDSC1 5.2092 7.2403 3.2421 2.7644
SJNB-5 GDSC1 5.3282 7.2348 3.3094 2.1244
SK-N-BE(2)-M17 GDSC1 5.4323 7.8961 3.0764 3.4436
CHP-126 GDSC1 5.4452 7.4866 3.2628 2.2239
IMR-5 GDSC1 5.4874 7.3924 3.3244 1.7923
SJNB-7 GDSC1 5.4905 11.518 1.3992 14.641
SK-N-DZ GDSC1 5.5205 7.0622 3.4746 0.951
SJNB-12 GDSC1 5.6102 7.8667 3.1863 2.4297
NB(TU)1 GDSC1 5.6796 11.2572 1.6578 12.5097
SK-N-FI GDSC1 5.7092 7.5592 3.3629 1.2985
SJNB-10 GDSC1 5.7779 8.0712 3.1856 2.1808
SJNB-13 GDSC1 5.8291 7.6458 3.3829 1.0734
NB1 GDSC1 5.8886 7.2573 3.5534 0.3666
KP-N-YS GDSC1 5.9748 8.6593 3.0375 2.7624
CHP-212 GDSC1 6.1146 7.8616 3.4215 0.6723
KP-N-YN GDSC1 6.1656 8.3333 3.2627 1.3016
GOTO GDSC1 6.1777 8.3678 3.2545 1.328
TGW GDSC1 6.1885 7.8319 3.4618 0.4882
MHH-NB-11 GDSC1 6.195 8.136 3.3516 0.8837
LA-N-6 GDSC1 6.2325 8.3464 3.287 1.1265
SK-N-AS GDSC1 6.2407 7.7555 3.5089 0.3279
NH-12 GDSC1 6.2835 7.9841 3.4435 0.4933
SiMa GDSC1 6.3255 9.5485 2.8402 3.4014
NB69 GDSC1 6.3768 8.2516 3.3826 0.6386
SK-N-SH GDSC1 6.3813 8.0914 3.4425 0.4459
SJNB-14 GDSC1 6.7389 8.1512 3.55 0.1125
GI-ME-N GDSC1 7.5443 9.9544 3.2182 0.5309
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 5.8976 7.6188 3.423 0.8323
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-51 GDSC1 3.0115 5.177 2.4693 16.1954
CAL-85-1 GDSC1 3.431 6.0104 2.4885 14.1288
HCC1806 GDSC1 3.439 4.4158 3.2395 8.398
HCC2157 GDSC1 4.3903 6.4237 3.0961 5.8327
MDA-MB-175-VII GDSC1 4.4223 6.4374 3.1128 5.6072
HCC38 GDSC1 4.4467 7.1261 2.7918 8.0128
AU565 GDSC1 4.5137 6.8616 2.9714 6.4256
CAL-120 GDSC1 4.6082 8.0765 2.4438 10.1549
DU4475 GDSC1 4.7714 7.5033 2.8422 6.6738
BT-474 GDSC1 5.0049 6.8146 3.3157 2.6626
Evsa-T GDSC1 5.3033 7.1406 3.3367 1.9961
MRK-nu-1 GDSC1 5.3228 9.649 2.1874 9.94
CAL-148 GDSC1 5.4074 8.843 2.6268 6.6199
ZR-75-30 GDSC1 5.4271 11.6289 1.2996 15.4232
MDA-MB-361 GDSC1 5.4519 10.1583 2.0307 10.671
CAMA-1 GDSC1 5.4751 10.0409 2.1028 10.1179
HCC1187 GDSC1 5.8035 7.9034 3.2678 1.685
HCC1428 GDSC1 5.843 7.2676 3.532 0.4591
MCF-7 GDSC1 5.8447 8.2373 3.1495 2.2946
BT-483 GDSC1 6.023 7.4908 3.521 0.3948
HCC70 GDSC1 6.0257 7.5095 3.5153 0.4103
MFM-223 GDSC1 6.0691 11.5825 1.7634 10.8409
HCC1954 GDSC1 6.0837 8.6413 3.0999 2.2437
BT-549 GDSC1 6.0934 7.7802 3.4431 0.6082
HCC1500 GDSC1 6.1149 7.8265 3.4347 0.6242
HCC1599 GDSC1 6.1224 8.073 3.3449 0.9721
UACC-812 GDSC1 6.1468 8.0942 3.3472 0.9417
JIMT-1 GDSC1 6.1597 7.721 3.4907 0.4152
Hs 578T GDSC1 6.2264 7.9779 3.4234 0.5922
OCUB-M GDSC1 6.2278 7.8517 3.4698 0.4426
HCC1395 GDSC1 6.2537 8.0446 3.4098 0.6222
EFM-19 GDSC1 6.2557 8.2288 3.3418 0.8754
HDQ-P1 GDSC1 6.3687 8.1882 3.4027 0.5761
MDA-MB-415 GDSC1 6.4143 8.7034 3.2277 1.2234
HCC1937 GDSC1 6.4297 8.4444 3.3326 0.7825
MDA-MB-453 GDSC1 6.4316 8.3104 3.3828 0.6047
HCC2218 GDSC1 6.4507 8.9905 3.1314 1.636
EFM-192A GDSC1 6.5524 8.2338 3.4561 0.3346
BT-20 GDSC1 6.5835 8.753 3.2802 0.8699
MDA-MB-157 GDSC1 6.5934 8.3783 3.4204 0.4087
MDA-MB-231 GDSC1 6.6214 8.3818 3.4296 0.3728
HCC1419 GDSC1 6.6687 7.9562 3.5908 0.0767
MDA-MB-468 GDSC1 6.6687 8.2989 3.4756 0.2508
UACC-893 GDSC1 6.7969 14.0812 1.0563 13.2598
MDA-MB-330 GDSC1 6.8265 8.6177 3.4223 0.3131
MDA-MB-436 GDSC1 6.9129 8.4353 3.5146 0.1284
COLO 824 GDSC1 6.9397 9.1382 3.2803 0.6454
T-47D GDSC1 7.0708 9.3266 3.2629 0.6287
HCC1569 GDSC1 7.1667 9.3886 3.2772 0.5399
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
M059J GDSC1 3.6525 5.8115 2.7905 10.8716
LN-18 GDSC1 4.3406 6.9627 2.7921 8.3484
LN-405 GDSC1 4.5673 6.4481 3.2104 4.4476
MOG-G-CCM GDSC1 4.6695 7.5065 2.7685 7.5197
Daoy GDSC1 4.844 6.7207 3.2622 3.3782
LN-229 GDSC1 4.886 6.8244 3.2402 3.4409
SF126 GDSC1 4.8912 6.3932 3.4391 2.0529
A-172 GDSC1 5.0792 6.9763 3.2859 2.7187
SW1783 GDSC1 5.0957 7.2231 3.1841 3.3822
8-MG-BA GDSC1 5.1103 7.1047 3.2462 2.9264
T98G GDSC1 5.1969 7.5884 3.0779 3.9075
NMC-G1 GDSC1 5.3342 6.7974 3.495 1.0529
DBTRG-05MG GDSC1 5.5341 7.8412 3.157 2.7367
D-247MG GDSC1 5.5972 7.7744 3.2189 2.2526
U-87MG ATCC GDSC1 5.6865 8.1121 3.1211 2.7083
GB-1 GDSC1 5.7885 8.0756 3.1891 2.1456
KNS-42 GDSC1 5.7944 7.1232 3.5655 0.3792
Hs 683 GDSC1 5.7945 7.244 3.5214 0.5259
D-542MG GDSC1 5.8346 7.4897 3.4456 0.7903
LNZTA3WT4 GDSC1 5.8418 7.5271 3.4344 0.8315
YH-13 GDSC1 5.8544 7.3128 3.5199 0.4927
U-118MG GDSC1 5.8876 7.3266 3.5279 0.4462
SF295 GDSC1 5.9186 7.3234 3.5411 0.388
CAS-1 GDSC1 5.9238 7.5018 3.478 0.5961
SF539 GDSC1 5.9254 7.5614 3.4564 0.6759
DK-MG GDSC1 5.972 7.3802 3.5412 0.3611
PFSK-1 GDSC1 6.0625 8.2712 3.2407 1.5183
AM-38 GDSC1 6.1128 9.4211 2.7818 4.1136
D283 Med GDSC1 6.1574 7.5597 3.5468 0.267
U-251MG GDSC1 6.2285 8.0695 3.3904 0.7083
Becker GDSC1 6.4115 7.8606 3.5344 0.2102
ONS-76 GDSC1 6.4275 7.8748 3.5352 0.204
Onda 10 GDSC1 6.4288 8.3329 3.3734 0.6377
KALS-1 GDSC1 6.4433 8.6544 3.259 1.0632
D-502MG GDSC1 6.4498 8.2195 3.4227 0.4698
GI-1 GDSC1 6.5253 8.503 3.3493 0.6606
GaMG GDSC1 6.5306 8.0147 3.5239 0.1969
H4 GDSC1 6.5357 8.1505 3.479 0.287
D-263MG GDSC1 6.5512 7.9039 3.5684 0.1211
MOG-G-UVW GDSC1 6.609 8.4383 3.405 0.4436
KINGS-1 GDSC1 6.6141 8.279 3.4628 0.2961
D-566MG GDSC1 6.6145 8.3328 3.4442 0.3394
SF268 GDSC1 6.6281 8.7296 3.3069 0.7423
42-MG-BA GDSC1 6.6531 7.9387 3.5913 0.0781
SW1088 GDSC1 6.6605 8.2972 3.4733 0.2581
KS-1 [Human Krukenberg tumour] GDSC1 6.6758 9.3427 3.0936 1.585
D-423MG GDSC1 6.7 8.7123 3.3415 0.5851
Onda 11 GDSC1 6.7155 8.516 3.4172 0.366
SK-MG-1 GDSC1 6.819 8.3148 3.5228 0.1343
D-336MG GDSC1 6.8557 8.9255 3.3246 0.5546
D-392MG GDSC1 7.0293 8.9782 3.3707 0.3586
KNS-81-FD GDSC1 7.1056 8.5263 3.5491 0.0661
SNB-75 GDSC1 7.3984 9.3583 3.3719 0.2443
YKG-1 GDSC1 7.7647 22.3917 -2.2786 24.3111
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 5.732 7.2714 3.4854 0.7098
TGBC24TKB GDSC1 5.7922 8.7494 2.9002 3.9304
ETK-1 GDSC1 6.9654 8.6803 3.4503 0.2159
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AN3-CA GDSC1 3.0225 7.2589 1.4983 22.9575
EN GDSC1 4.0946 7.0201 2.5681 10.9169
MFE-296 GDSC1 5.1172 7.3445 3.1416 3.6324
RL95-2 GDSC1 5.183 6.7634 3.4352 1.587
KLE GDSC1 5.6561 7.783 3.2453 2.0095
ESS-1 GDSC1 6.3123 7.9157 3.479 0.3758
MFE-280 GDSC1 6.7715 8.9931 3.2671 0.7897
MFE-319 GDSC1 7.4656 15.5293 0.804 13.0978
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O GDSC1 2.4561 4.6805 2.0903 21.7686
UO-31 GDSC1 3.6172 7.3431 1.9996 16.9838
CAL-54 GDSC1 5.001 7.3301 3.0769 4.3504
RCC10RGB GDSC1 5.279 7.0529 3.3616 1.8828
KMRC-1 GDSC1 5.4443 13.9319 0.1803 21.2651
769-P GDSC1 5.5409 7.7868 3.1841 2.5549
KMRC-20 GDSC1 5.637 8.5873 2.8842 4.3325
BB65-RCC GDSC1 5.7072 7.9405 3.2049 2.1712
VMRC-RCW GDSC1 5.8625 8.5911 3.0078 3.1216
LB1047-RCC GDSC1 5.8918 8.1063 3.2271 1.7935
SW13 GDSC1 6.0752 8.1345 3.3005 1.2143
A-498 GDSC1 6.0866 7.5681 3.5175 0.3734
OS-RC-2 GDSC1 6.1797 8.0582 3.3746 0.8037
A-704 GDSC1 6.2541 7.702 3.5326 0.265
HA7-RCC GDSC1 6.2736 8.4938 3.2477 1.2651
BFTC-909 GDSC1 6.3237 7.8628 3.5019 0.3118
SN12C GDSC1 6.617 8.2794 3.4637 0.293
VMRC-RCZ GDSC1 6.6512 8.1914 3.5062 0.1973
TK-10 GDSC1 6.701 8.8676 3.2852 0.7716
LB996-RCC GDSC1 6.7565 8.6222 3.3951 0.4052
LB2241-RCC GDSC1 6.8211 8.4595 3.4747 0.2096
ACHN GDSC1 6.8719 8.339 3.5327 0.1124
Caki-1 GDSC1 6.9391 9.1091 3.2906 0.6138
SW156 GDSC1 7.0611 8.9712 3.3847 0.3165
RXF 393L GDSC1 7.5811 9.9726 3.2255 0.4973
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCT 15 GDSC1 3.9878 16.626 -2.3232 33.9039
HT-29 GDSC1 4.4199 5.9356 3.3559 3.7457
COLO 678 GDSC1 4.5658 6.5351 3.1674 4.7777
CCK-81 GDSC1 4.6799 8.0292 2.5201 9.3642
HT-55 GDSC1 4.7275 7.4739 2.8256 6.9211
HCT 116 GDSC1 4.9246 8.058 2.6803 7.4634
LS180 GDSC1 5.1205 10.8475 1.4593 15.357
KM12 GDSC1 5.193 14.6054 -0.3443 24.2549
SW948 GDSC1 5.4694 7.2007 3.395 1.4187
SNU-C1 GDSC1 5.552 8.1538 3.0294 3.5292
COLO 320HSR GDSC1 5.5547 8.9506 2.6692 5.9812
T84 GDSC1 5.5576 7.8146 3.181 2.5469
CW-2 GDSC1 5.5994 12.7114 0.8946 17.2385
SW48 GDSC1 5.6446 7.7501 3.2533 1.9795
MDST8 GDSC1 5.7141 7.3605 3.4435 0.9057
LS411N GDSC1 5.7215 6.8391 3.6389 0.2119
NCI-H716 GDSC1 5.8894 8.4135 3.0979 2.5323
SW620 GDSC1 5.8951 8.5124 3.0587 2.7576
SW1463 GDSC1 5.8992 10.3787 2.2203 8.2666
LS513 GDSC1 5.9886 7.4794 3.5119 0.4407
COLO205 GDSC1 6.0757 7.4873 3.5421 0.3113
SW1417 GDSC1 6.1038 9.7125 2.648 4.9886
C2BBe1 GDSC1 6.2029 13.6276 0.8754 15.7013
NCI-H747 GDSC1 6.2671 8.7436 3.1457 1.7677
HT115 GDSC1 6.2989 7.6275 3.5742 0.1669
CL-11 GDSC1 6.3121 8.5749 3.233 1.2955
RKO GDSC1 6.316 8.4199 3.2946 1.0207
LoVo GDSC1 6.3424 8.1566 3.4038 0.5879
LS123 GDSC1 6.3696 8.0128 3.4661 0.3851
RCM-1 [Human ESC] GDSC1 6.4819 7.86 3.5593 0.1484
LS1034 GDSC1 6.5524 7.9308 3.5598 0.133
GP5d GDSC1 6.5596 8.1386 3.4918 0.2514
SW837 GDSC1 6.5697 8.3659 3.4159 0.4315
SW626 GDSC1 6.6102 8.5747 3.3564 0.5874
CaR-1 GDSC1 6.6261 8.3772 3.4329 0.3626
HCC2998 GDSC1 6.6283 8.3856 3.4308 0.367
SNU-C2B GDSC1 7.1926 9.5595 3.2259 0.6773
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 5.603 7.8791 3.1772 2.497
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-2 GDSC1 3.6372 4.4602 3.4257 6.0413
Hep-G2/C3A GDSC1 4.2506 8.4852 1.9627 14.8518
JHH-6 GDSC1 5.0874 19.7391 -2.9827 32.2611
SNU-475 GDSC1 5.3127 8.6634 2.6505 6.6794
JHH-1 GDSC1 5.5678 7.3154 3.3951 1.2965
HLE GDSC1 5.6132 9.0811 2.6449 6.0193
Hep 3B2.1-7 GDSC1 5.7125 7.3794 3.4355 0.9435
SK-HEP-1 GDSC1 5.7381 7.6952 3.3215 1.4789
HuH-1 GDSC1 5.814 7.0417 3.6019 0.2666
JHH-4 GDSC1 6.105 9.9845 2.5267 5.7787
SNU-423 GDSC1 6.1093 7.9108 3.401 0.7539
JHH-7 GDSC1 6.1687 7.7781 3.4736 0.4622
Huh-7 GDSC1 6.2312 7.6501 3.5423 0.251
SNU-398 GDSC1 6.3676 8.1112 3.4301 0.4898
SNU-387 GDSC1 6.6609 8.3883 3.4419 0.3275
SNU-449 GDSC1 6.9485 8.6434 3.4569 0.2087
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2369 GDSC1 2.2394 9.9508 -0.5454 35.9274
NCI-H2405 GDSC1 4.2289 5.665 3.3497 4.3575
NCI-H1437 GDSC1 4.2377 5.9855 3.1977 5.5167
COR-L23 GDSC1 4.564 6.4298 3.217 4.4066
NCI-H661 GDSC1 4.6465 6.2335 3.3651 3.0925
LCLC-103H GDSC1 4.6573 6.6632 3.1683 4.5255
NCI-H727 GDSC1 4.7561 7.4449 2.8597 6.5839
RERF-LC-Sq1 GDSC1 4.8115 9.3022 1.9911 12.7959
NCI-H2009 GDSC1 4.9447 11.3107 1.099 18.0617
LK-2 GDSC1 4.9991 12.5032 0.5496 20.8445
NCI-H2135 GDSC1 5.0038 7.5759 2.9634 5.1675
NCI-H460 GDSC1 5.0529 8.1065 2.744 6.6526
NCI-H2141 GDSC1 5.0679 7.6511 2.9692 4.9718
SK-MES-1 GDSC1 5.0866 7.0577 3.2537 2.9228
NCI-H209 GDSC1 5.087 8.1504 2.7458 6.5523
RERF-LC-MS GDSC1 5.104 9.4398 2.1362 10.9069
NCI-H720 GDSC1 5.1322 7.3011 3.1703 3.4017
NCI-H345 GDSC1 5.1423 5.9077 3.752 0.161
BEN GDSC1 5.1939 9.1161 2.3556 9.1004
IST-SL2 GDSC1 5.1992 8.2203 2.786 5.9815
NCI-H64 GDSC1 5.2138 7.7946 2.9935 4.4635
COR-L95 GDSC1 5.2139 6.9495 3.3718 1.9237
NCI-H2804 GDSC1 5.2185 7.4981 3.1318 3.4899
NCI-H226 GDSC1 5.2301 9.0468 2.4136 8.589
NCI-H1436 GDSC1 5.2456 7.3255 3.2247 2.8111
SBC-5 GDSC1 5.2659 6.3738 3.6304 0.4923
Calu-6 GDSC1 5.271 6.9838 3.3869 1.7424
COLO 668 GDSC1 5.2838 7.6583 3.0976 3.5918
NCI-H526 GDSC1 5.2899 6.8625 3.4471 1.366
Lu-139 GDSC1 5.3012 7.053 3.373 1.7799
NCI-H2444 GDSC1 5.3292 6.3659 3.659 0.3425
SW1573 GDSC1 5.3535 7.562 3.1804 2.9038
CPC-N GDSC1 5.3576 7.4007 3.2533 2.427
NCI-H1048 GDSC1 5.4233 6.9075 3.4919 0.9688
NCI-H1703 GDSC1 5.4443 7.6286 3.201 2.6109
NCI-H1092 GDSC1 5.4547 7.1549 3.4068 1.3735
NCI-H3122 GDSC1 5.4685 8.0739 3.0176 3.7673
NCI-H1963 GDSC1 5.5164 10.3718 1.9721 10.894
NCI-H211 GDSC1 5.5205 8.2139 2.9847 3.8869
SK-LU-1 GDSC1 5.5771 7.3576 3.3824 1.352
NCI-H1304 GDSC1 5.5783 7.8178 3.1906 2.4545
NCI-H2227 GDSC1 5.5789 11.3855 1.526 13.6126
NCI-H82 GDSC1 5.5955 7.3025 3.4132 1.1717
HCC33 GDSC1 5.5963 7.2996 3.4148 1.1631
NCI-H2196 GDSC1 5.603 7.5184 3.329 1.6079
NCI-H2171 GDSC1 5.6344 7.1606 3.4863 0.7885
NCI-H1869 GDSC1 5.6461 8.5198 2.9198 4.0772
NCI-H196 GDSC1 5.6875 7.0297 3.5576 0.4675
NCI-H510A GDSC1 5.689 7.5791 3.3454 1.4124
NCI-H1155 GDSC1 5.6912 7.4915 3.3817 1.2237
NCI-H2347 GDSC1 5.6964 8.37 3.0143 3.3649
NCI-H1581 GDSC1 5.7257 7.363 3.4476 0.8765
NCI-H847 GDSC1 5.7699 7.4139 3.4471 0.8393
Lu-165 GDSC1 5.8108 7.2067 3.5415 0.4464
NCI-H187 GDSC1 5.8134 6.9279 3.6413 0.1752
NCI-H1573 GDSC1 5.8188 7.929 3.2646 1.6825
NCI-H1694 GDSC1 5.8253 8.5142 3.0213 3.0997
COR-L88 GDSC1 5.8294 7.9865 3.2462 1.7693
IST-SL1 GDSC1 5.8315 7.8227 3.3137 1.4093
NCI-H2081 GDSC1 5.8428 9.1031 2.7713 4.6821
NCI-H2029 GDSC1 5.8437 7.5188 3.4383 0.8131
Calu-3 GDSC1 5.8629 7.71 3.3727 1.0873
NCI-H1563 GDSC1 5.8635 7.3062 3.5259 0.4669
NCI-H1838 GDSC1 5.9511 7.9767 3.3071 1.3105
NCI-H2722 GDSC1 5.9635 7.5988 3.458 0.6424
NCI-H2291 GDSC1 5.9928 8.1441 3.2594 1.5021
NCI-H1915 GDSC1 6.0023 7.399 3.5459 0.3334
NCI-H1944 GDSC1 6.0099 7.8597 3.3786 0.9249
NCI-H810 GDSC1 6.0252 7.4248 3.5453 0.3246
LB647-SCLC GDSC1 6.031 8.0485 3.3146 1.1923
NCI-H1836 GDSC1 6.0394 8.6191 3.0871 2.3769
NCI-H1435 GDSC1 6.0496 7.6602 3.4699 0.543
NCI-H838 GDSC1 6.0748 7.4855 3.5424 0.3109
NCI-H1781 GDSC1 6.0764 7.2645 3.6194 0.1437
NCI-H841 GDSC1 6.0982 7.5022 3.5452 0.294
HCC827 GDSC1 6.0983 8.5794 3.1325 2.0439
NCI-H1355 GDSC1 6.0993 8.6022 3.1237 2.0909
NCI-H2122 GDSC1 6.1003 7.538 3.5334 0.3236
NCI-H358 GDSC1 6.1051 8.1593 3.304 1.1689
NCI-H2373 GDSC1 6.1185 10.5847 2.2609 7.501
Ms-1 GDSC1 6.1333 7.7832 3.4579 0.5324
HCC78 GDSC1 6.1369 7.5461 3.5441 0.2815
NCI-H1770 GDSC1 6.1676 7.69 3.5048 0.3711
NCI-H1876 GDSC1 6.1723 10.0021 2.5577 5.4434
DMS 114 GDSC1 6.2098 7.9405 3.4305 0.5783
HOP-62 GDSC1 6.2116 7.8278 3.4722 0.4438
DMS 79 GDSC1 6.2151 7.9558 3.427 0.5868
NCI-H1648 GDSC1 6.223 8.7655 3.1162 1.9746
NCI-H596 GDSC1 6.2269 7.7385 3.5097 0.3314
EPLC-272H GDSC1 6.2317 8.2756 3.3139 1.0104
NCI-H446 GDSC1 6.2622 7.8048 3.4995 0.3431
NCI-H1693 GDSC1 6.2706 8.0194 3.4257 0.5579
Lu-65 GDSC1 6.2744 8.182 3.3672 0.7628
NCI-H1793 GDSC1 6.2809 8.232 3.3511 0.8195
NCI-H524 GDSC1 6.2816 8.094 3.4027 0.6289
NCI-H1688 GDSC1 6.2902 7.9158 3.4707 0.4092
NCI-H1755 GDSC1 6.2974 8.2211 3.362 0.766
NCI-H1651 GDSC1 6.3028 8.3486 3.3162 0.9419
NCI-H2170 GDSC1 6.3203 7.703 3.556 0.1945
LC-2/ad GDSC1 6.35 8.2326 3.379 0.6682
NCI-H2085 GDSC1 6.354 8.2292 3.3818 0.6558
UMC-11 GDSC1 6.3572 7.8577 3.5159 0.2664
NCI-H2803 GDSC1 6.3584 8.0772 3.4388 0.4683
Lu-99A GDSC1 6.3646 8.3425 3.344 0.7856
SBC-1 GDSC1 6.3695 8.1308 3.4238 0.5083
NCI-H23 GDSC1 6.3698 8.272 3.3723 0.6788
NCI-H1792 GDSC1 6.3895 8.0655 3.4548 0.4069
NCI-H1975 GDSC1 6.3931 7.9782 3.487 0.3211
IA-LM GDSC1 6.4055 7.5565 3.6342 0.066
PC-14 GDSC1 6.4189 8.1676 3.4295 0.4651
SBC-3 GDSC1 6.4427 8.0116 3.4935 0.287
Lu-135 GDSC1 6.4429 8.6631 3.2555 1.0781
NCI-H69 GDSC1 6.4484 8.263 3.4066 0.519
NCI-H748 GDSC1 6.4541 8.8506 3.1879 1.3654
SHP-77 GDSC1 6.4582 7.8384 3.5584 0.1552
NCI-H1993 GDSC1 6.4711 8.1793 3.4451 0.3965
NCI-H2342 GDSC1 6.4921 8.7896 3.2281 1.1527
NCI-H2172 GDSC1 6.5012 7.8614 3.5655 0.1349
NCI-H2795 GDSC1 6.5076 8.5705 3.3173 0.785
CAL-12T GDSC1 6.508 8.5127 3.3388 0.7074
A-549 GDSC1 6.52 8.5779 3.3195 0.7684
NCI-H1623 GDSC1 6.5307 8.5556 3.3321 0.7165
A-427 GDSC1 6.5372 8.6033 3.3171 0.7657
NCI-H522 GDSC1 6.5552 8.5847 3.3312 0.7039
NCI-H513 GDSC1 6.5604 8.2538 3.452 0.3415
NCI-H290 GDSC1 6.572 8.0633 3.5219 0.1896
NCI-H322M GDSC1 6.5721 8.5771 3.3407 0.6611
DMS 273 GDSC1 6.5783 8.0323 3.5346 0.1664
Lu-134-A GDSC1 6.586 8.3076 3.4426 0.3545
NCI-H1568 GDSC1 6.6033 8.5487 3.3632 0.5698
NCI-H292 GDSC1 6.6075 8.0523 3.538 0.1544
NCI-H650 GDSC1 6.639 8.2896 3.4682 0.2759
HARA [Human squamous cell lung carcinoma] GDSC1 6.6457 8.9801 3.2204 1.0571
NCI-H2461 GDSC1 6.6506 8.7337 3.3143 0.7023
HCC44 GDSC1 6.6524 8.5117 3.3952 0.4506
NCI-H647 GDSC1 6.6714 8.4033 3.4404 0.327
NCI-H2087 GDSC1 6.6779 8.5739 3.3827 0.4737
NCI-H1299 GDSC1 6.7262 8.4687 3.4376 0.3136
NCI-H2818 GDSC1 6.7603 8.4119 3.4695 0.2358
RERF-LC-KJ GDSC1 6.7614 8.3015 3.5074 0.1688
NCI-H2591 GDSC1 6.7673 8.6475 3.3902 0.4134
DMS 53 GDSC1 6.7811 8.602 3.4112 0.3552
NCI-H2110 GDSC1 6.7884 8.8645 3.3207 0.6018
LXF 289 GDSC1 6.7965 8.4063 3.4841 0.1993
NCI-H1734 GDSC1 6.8145 8.2835 3.5317 0.1232
NCI-H3255 GDSC1 6.8153 8.8442 3.3383 0.5346
NCI-H2731 GDSC1 6.8365 9.0647 3.2666 0.7501
HOP-92 GDSC1 6.8423 8.9083 3.3256 0.5584
LCLC-97TM1 GDSC1 6.8642 20.21 -1.8596 25.079
PaCa-3 GDSC1 6.8739 8.6108 3.4417 0.2572
LOU-NH91 GDSC1 6.8741 8.678 3.4186 0.3051
NCI-H2869 GDSC1 6.8784 8.6873 3.417 0.3073
EBC-1 GDSC1 6.9278 8.6306 3.454 0.219
NCI-H1666 GDSC1 6.9343 13.2401 1.5361 10.237
NCI-H2595 GDSC1 6.9352 8.9546 3.3443 0.4617
SW1271 GDSC1 6.9427 8.5652 3.4813 0.17
EKVX GDSC1 6.9483 9.1224 3.2893 0.6128
NCI-H2030 GDSC1 6.9835 8.7821 3.422 0.2639
NCI-H2023 GDSC1 6.9851 8.803 3.4154 0.2765
COR-L105 GDSC1 6.9965 9.0436 3.3357 0.4578
LC-1/sq GDSC1 7.0029 9.0525 3.3349 0.4571
NCI-H2228 GDSC1 7.025 15.1832 0.6839 14.689
ChaGo-K-1 GDSC1 7.0955 8.9698 3.3975 0.2794
HCC15 GDSC1 7.1083 8.8451 3.4444 0.1918
ABC-1 GDSC1 7.165 9.3096 3.3046 0.4673
NCI-H520 GDSC1 7.1734 8.8722 3.4577 0.1582
NCI-H441 GDSC1 7.2332 8.7219 3.5275 0.0714
NCI-H1650 GDSC1 7.3715 9.0241 3.4744 0.1057
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 6.6102 8.5029 3.3824 0.5079
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-140 GDSC1 4.4906 6.2594 3.2485 4.3683
T.T GDSC1 4.7911 7.6738 2.7733 7.1369
KYSE-450 GDSC1 4.9599 6.9238 3.2395 3.283
COLO 680N GDSC1 5.1592 7.4027 3.1401 3.5548
KYSE-150 GDSC1 5.1812 6.5733 3.5136 1.1412
KYSE-510 GDSC1 5.2541 12.5949 0.6977 19.3018
TE-6 GDSC1 5.2773 7.4731 3.177 3.0687
KYSE-270 GDSC1 5.2829 8.4271 2.7424 6.0936
KYSE-180 GDSC1 5.3684 9.8891 2.1031 10.4012
KYSE-70 GDSC1 5.4174 10.297 1.9402 11.3762
TE-11 GDSC1 5.64 7.6814 3.2797 1.8344
TE-9 GDSC1 5.9024 7.3157 3.5376 0.4072
OE19 GDSC1 5.948 9.7714 2.5308 6.0734
TE-1 GDSC1 6.2135 9.2538 2.9078 3.1708
EC-GI-10 GDSC1 6.3044 8.0184 3.4392 0.4955
OE21 GDSC1 6.3715 8.1919 3.4024 0.5754
TE-5 GDSC1 6.4025 7.9114 3.5137 0.2558
TE-15 GDSC1 6.4776 8.3093 3.4011 0.5204
OE33 GDSC1 6.6642 8.2994 3.4738 0.2558
TE-10 GDSC1 6.8273 8.5979 3.4295 0.2972
KYSE-410 GDSC1 7.082 8.6813 3.4902 0.1309
TE-8 GDSC1 7.1849 14.138 1.2754 11.1854
KYSE-520 GDSC1 7.275 9.0478 3.4338 0.1726
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OV-90 GDSC1 3.7047 7.1869 2.1542 15.5102
OAW42 GDSC1 4.009 5.1909 3.4121 4.6041
RMG-I GDSC1 4.5919 8.7265 2.1101 12.6507
OVCAR-5 GDSC1 4.8317 9.1334 2.0892 12.0453
Caov-3 GDSC1 4.9742 6.9229 3.2485 3.1893
A2780 GDSC1 5.176 7.8032 2.9663 4.7415
ES-2 GDSC1 5.2449 7.2695 3.2491 2.652
OVISE GDSC1 5.5528 8.6198 2.8201 4.9407
FU-OV-1 GDSC1 5.6668 7.8894 3.2059 2.2249
OVCAR-3 GDSC1 5.6965 7.2848 3.4652 0.8255
TOV-112D GDSC1 5.791 10.8825 1.9125 10.5744
EFO-21 GDSC1 5.9237 7.546 3.4615 0.6577
EFO-27 GDSC1 5.9457 8.0487 3.2759 1.4721
OVKATE GDSC1 6.0071 7.9046 3.3601 1.0079
OC 314 GDSC1 6.0602 7.3532 3.5833 0.2186
Kuramochi GDSC1 6.2376 8.2375 3.331 0.9341
OVTOKO GDSC1 6.3903 8.3201 3.3628 0.6993
TYK-nu GDSC1 6.4384 8.1238 3.4525 0.3911
IGROV-1 GDSC1 6.6417 8.3576 3.4456 0.3259
OVCAR-8 GDSC1 6.6682 8.2763 3.4832 0.2357
SK-OV-3 GDSC1 6.7924 8.3846 3.4901 0.19
OVCAR-4 GDSC1 6.8481 8.534 3.4588 0.2315
TOV-21G GDSC1 6.8913 18.8039 -1.1526 22.7547
Caov-4 GDSC1 6.905 8.5982 3.457 0.2196
OAW28 GDSC1 7.4445 9.2026 3.44 0.1341
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaTu 8988t GDSC1 4.4365 6.823 2.9337 6.9491
SU.86.86 GDSC1 4.7203 24.1683 -5.4904 37.1777
MIA PaCa-2 GDSC1 4.8506 7.0211 3.1259 4.3519
HPAF-II GDSC1 4.877 7.0646 3.1224 4.3135
MZ-PC-1 GDSC1 5.0212 10.5643 1.5251 15.2469
Panc 04.03 GDSC1 5.3439 12.35 0.8852 18.0338
PL4 GDSC1 5.5231 11.392 1.4835 14.0314
YAPC GDSC1 5.8833 6.9757 3.6498 0.1391
SUIT-2 GDSC1 5.8911 7.3114 3.5348 0.4221
KP-4 GDSC1 6.0702 7.4278 3.561 0.2662
PaTu 8902 GDSC1 6.0807 7.3724 3.584 0.2103
CFPAC-1 GDSC1 6.0854 7.6886 3.4736 0.5088
KP-2 GDSC1 6.1646 7.4574 3.5848 0.1834
DAN-G GDSC1 6.2 7.4318 3.6059 0.1371
HPAC GDSC1 6.2484 7.8913 3.4635 0.4509
Panc 03.27 GDSC1 6.2763 7.9414 3.4562 0.4585
Capan-1 GDSC1 6.3123 10.49 2.4193 6.0648
Hs 766T GDSC1 6.3611 8.0212 3.4599 0.406
Panc 02.03 GDSC1 6.3897 8.0976 3.4435 0.439
KP-1N GDSC1 6.442 8.3013 3.3901 0.5745
Panc 08.13 GDSC1 6.4547 8.3422 3.3802 0.5995
HuP-T4 GDSC1 6.5552 7.9985 3.538 0.1662
PSN1 GDSC1 6.595 8.3419 3.4339 0.3729
HuP-T3 GDSC1 6.6105 8.9125 3.2313 1.041
Panc 10.05 GDSC1 6.6685 8.3697 3.4511 0.3034
SW1990 GDSC1 6.7143 8.8089 3.312 0.6717
KP-3 GDSC1 6.7489 8.7118 3.3604 0.5031
AsPC-1 GDSC1 7.007 8.957 3.37 0.3684
Capan-2 GDSC1 7.0183 8.7955 3.4297 0.2393
BxPC-3 GDSC1 7.3352 9.2297 3.3934 0.2229
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 GDSC1 5.7241 7.9317 3.2171 2.0757
MSTO-211H GDSC1 5.7452 8.2653 3.0862 2.8287
NCI-H2052 GDSC1 5.831 8.0578 3.2175 1.9253
IST-Mes1 GDSC1 6.294 8.0911 3.4087 0.6007
NCI-H28 GDSC1 6.4625 8.2153 3.429 0.4451
MPP 89 GDSC1 6.5651 8.1141 3.5022 0.2286
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1 5.9667 12.4636 1.2739 14.0858
PC-3 GDSC1 6.1727 8.4115 3.2351 1.4264
LNCaP clone FGC GDSC1 6.5987 8.8218 3.2606 0.9337
22Rv1 GDSC1 6.7014 9.093 3.2009 1.0916
DU145 GDSC1 6.7352 8.757 3.339 0.5739
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 5.2251 9.7307 2.0803 10.9531
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-24 GDSC1 2.2284 3.6424 2.1512 22.6419
SK-MEL-30 GDSC1 2.5938 4.3388 2.3611 19.1357
MeWo GDSC1 2.8325 5.0074 2.3582 17.8977
G-mel GDSC1 3.4723 4.2837 3.3278 7.5874
SK-MEL-28 GDSC1 4.2481 9.1664 1.6205 17.1931
CHL-1 GDSC1 4.4448 6.047 3.3193 3.9556
RVH-421 GDSC1 4.4819 6.5086 3.1211 5.3678
CP66-MEL GDSC1 4.7653 6.6447 3.248 3.6638
WM793 GDSC1 4.89 7.3652 2.9888 5.2643
SK-MEL-1 GDSC1 5.0855 7.5214 3.0408 4.4154
A-431 GDSC1 5.1291 7.2533 3.1901 3.2719
MZ-MEL-7 GDSC1 5.1671 7.2155 3.2292 2.9303
WT2-iPS GDSC1 5.1893 7.5125 3.1081 3.7139
IGR-1 GDSC1 5.2176 7.0871 3.3142 2.2793
RPMI-7951 GDSC1 5.2922 12.5391 0.7537 18.8933
M14 GDSC1 5.3567 8.9038 2.5656 7.1781
SK-MEL-2 GDSC1 5.4095 6.3374 3.6998 0.1843
UACC-257 GDSC1 5.415 7.4393 3.2673 2.2445
WM1552C GDSC1 5.5277 11.2241 1.5683 13.4902
A-375 GDSC1 5.6258 7.483 3.3545 1.4408
WM278 GDSC1 5.6412 9.0008 2.6989 5.5853
VMRC-MELG GDSC1 5.6441 7.057 3.5298 0.6004
COLO 783 GDSC1 5.6996 7.4137 3.4163 1.0458
LB373-MEL-D GDSC1 5.712 6.8616 3.6275 0.2435
COLO 800 GDSC1 5.7132 9.7893 2.3781 7.6318
IPC-298 GDSC1 5.7166 6.8636 3.6285 0.2391
WM115 GDSC1 5.735 12.9177 0.8913 16.8739
UACC-62 GDSC1 5.7416 6.8652 3.6371 0.2086
Mel Ho GDSC1 5.7514 10.9737 1.8426 11.1327
SH-4 GDSC1 5.7617 12.7355 0.9991 16.2075
WM35 GDSC1 5.8453 12.3227 1.2581 14.5015
SK-MEL-5 GDSC1 5.8536 7.3189 3.5173 0.5021
HMV-II GDSC1 5.8705 10.6452 2.077 9.2911
A101D GDSC1 5.889 7.3784 3.5096 0.5067
LB2518-MEL GDSC1 5.9423 7.6505 3.4298 0.7678
MMAc-SF GDSC1 5.955 8.2176 3.2119 1.7959
LOX-IMVI GDSC1 5.9562 8.4471 3.1175 2.3203
COLO 679 GDSC1 6.0521 7.5885 3.497 0.4526
A2058 GDSC1 6.0599 7.379 3.5743 0.2389
451Lu GDSC1 6.0734 7.8037 3.4264 0.6831
GAK GDSC1 6.0983 7.4434 3.5658 0.2445
Hs 938.T GDSC1 6.1141 9.1178 2.9141 3.289
HT-144 GDSC1 6.1148 7.7158 3.4752 0.4867
IGR-37 GDSC1 6.2858 7.424 3.6378 0.0781
IST-MEL1 GDSC1 6.3008 8.339 3.3189 0.9322
COLO 829 GDSC1 6.362 8.0492 3.4503 0.4329
G-361 GDSC1 6.3727 7.9188 3.5003 0.2968
Hs 940.T GDSC1 6.4581 8.0821 3.4745 0.3262
MZ-MEL-2 GDSC1 6.5235 8.2237 3.4489 0.364
CP50-MEL-B GDSC1 6.5914 7.9559 3.5648 0.1187
COLO 792 GDSC1 6.7069 8.2635 3.5012 0.1919
A-388 GDSC1 6.7384 8.4943 3.4332 0.3194
DJM-1 GDSC1 6.9786 8.7797 3.4211 0.2671
Mel JuSo GDSC1 8.6266 16.0695 1.2453 8.6167
SK-MEL-3 GDSC1 9.2952 23.3018 -1.6751 19.4901
EquiPSC Line K2 GDSC1 7.4271 9.4513 3.3503 0.2757
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 6.1182 7.6936 3.4846 0.4554
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-LMS-1 GDSC1 3.6479 9.2027 1.0997 22.6831
A-204 GDSC1 3.95 6.3118 2.8022 9.6207
SK-UT-1 GDSC1 4.8552 7.2495 3.0208 5.1154
Hs 633.T GDSC1 5.1797 6.9669 3.346 2.1418
EW-8 GDSC1 5.1805 7.7926 2.9739 4.677
Rh41 GDSC1 5.196 8.5592 2.6236 7.1644
MES-SA GDSC1 5.451 6.8787 3.5157 0.8269
SW872 GDSC1 5.4592 7.1335 3.4176 1.3093
TE 441.T GDSC1 5.5194 7.2533 3.3975 1.3427
HT-1080 GDSC1 5.5727 9.7498 2.3064 8.4658
SW982 GDSC1 5.9027 7.3868 3.5119 0.4902
SW684 GDSC1 6.0507 7.2745 3.607 0.1731
KYM-1 GDSC1 6.0915 11.0136 2.0453 8.9757
RKN GDSC1 6.2405 7.3843 3.6357 0.0873
GCT GDSC1 6.4187 7.9485 3.5067 0.2657
MFH-ino GDSC1 6.5868 8.4191 3.4034 0.4585
VA-ES-BJ GDSC1 6.6339 8.0219 3.5573 0.1211
RD GDSC1 6.6878 11.4542 2.2029 6.7021
Rh30 GDSC1 6.7356 8.658 3.3746 0.4694
G-401 GDSC1 6.9256 8.9049 3.3583 0.4292
STS-0421 GDSC1 7.7832 9.8335 3.3451 0.2006
G-402 GDSC1 8.5352 19.8409 -0.535 16.8955
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NUGC-3 GDSC1 2.1255 34.199 -12.6886 46.3886
MKN28 GDSC1 4.0125 6.2394 2.8907 8.6984
MKN45 GDSC1 4.2189 6.3926 2.9809 7.2757
ECC12 GDSC1 4.4569 6.1539 3.276 4.2521
HGC-27 GDSC1 4.7312 6.3433 3.3671 2.8816
NUGC-4 GDSC1 4.8742 7.089 3.1091 4.4176
HSC-39 GDSC1 4.9626 9.1029 2.1995 10.8692
ECC10 GDSC1 5.1052 7.8092 2.9189 5.2469
SCH GDSC1 5.387 7.139 3.3802 1.6124
NCI-N87 GDSC1 5.4193 9.714 2.2217 9.4447
RF-48 GDSC1 5.4309 7.663 3.1787 2.7764
SNU-5 GDSC1 5.5807 7.1889 3.4516 0.9989
AGS GDSC1 5.7904 7.1338 3.5601 0.3981
SNU-16 GDSC1 5.8914 11.675 1.6014 12.3056
TGBC11TKB GDSC1 6.1443 10.9575 2.1045 8.4691
MKN7 GDSC1 6.2325 9.3964 2.8568 3.4481
23132/87 GDSC1 6.2486 7.9952 3.4259 0.5705
OCUM-1 GDSC1 6.2831 8.1858 3.3693 0.7485
SNU-1 GDSC1 6.2963 8.4628 3.2697 1.1452
MKN1 GDSC1 6.3242 7.6518 3.5747 0.1596
TMK-1 GDSC1 6.3455 8.2458 3.3723 0.695
GCIY GDSC1 6.3578 8.2619 3.3713 0.6904
Hs 746.T GDSC1 6.4438 11.6224 1.9817 8.5924
Fu97 GDSC1 6.5113 8.1088 3.4846 0.2829
IM95 GDSC1 6.6464 8.4747 3.4061 0.4237
RERF-GC-1B GDSC1 7.0156 9.2127 3.2827 0.5978
SNG-M GDSC1 6.2536 7.7986 3.4985 0.3495
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-62 GDSC1 3.7152 7.1677 2.173 15.3304
CGTH-W-1 GDSC1 5.2206 7.3069 3.2189 2.8971
TT2609-C02 GDSC1 5.3429 11.3967 1.3524 15.3508
ASH-3 GDSC1 5.4698 9.8497 2.1908 9.527
TT GDSC1 5.6592 8.2431 3.0496 3.2043
IHH-4 GDSC1 5.8158 7.2845 3.515 0.5348
FTC-133 GDSC1 5.8438 7.5131 3.4406 0.8035
WRO GDSC1 6.0057 7.3041 3.5805 0.2439
8305C GDSC1 6.0303 12.7265 1.1909 14.3995
BHT-101 GDSC1 6.1076 7.342 3.6041 0.1629
K5 GDSC1 6.144 7.6954 3.4939 0.4137
B-CPAP GDSC1 6.3101 7.5726 3.5966 0.1277
ML-1 [Human leukemia] GDSC1 6.318 7.9203 3.4795 0.3719
8505C GDSC1 6.4534 8.0808 3.4733 0.3312
KMH-2 GDSC1 6.4933 8.2894 3.4143 0.4726
HTC-C3 GDSC1 6.6894 8.5827 3.3839 0.4649
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-15A GDSC1 2.5669 5.3676 1.9288 22.3038
SAT [Human HNSCC] GDSC1 4.0251 5.384 3.3288 5.2036
KON GDSC1 4.1035 7.3313 2.4198 12.0193
NCI-H3118 GDSC1 4.3075 10.3603 1.0724 20.352
HSC-2 GDSC1 4.5767 6.222 3.325 3.5612
CAL-27 GDSC1 4.5904 7.7662 2.5834 9.1604
BICR 78 GDSC1 4.872 6.5648 3.3508 2.6912
HSC-3 GDSC1 4.9484 7.3356 3.0408 4.7371
SCC-4 GDSC1 5.1041 8.2382 2.7154 6.731
OSC-20 GDSC1 5.1623 7.4316 3.1288 3.627
SCC-25 GDSC1 5.4297 11.8436 1.1965 16.0247
JHU-011 GDSC1 5.4898 13.453 0.4503 19.8521
BB30-HNC GDSC1 5.4971 7.4002 3.326 1.7693
HO-1-u-1 GDSC1 5.5822 7.4699 3.3389 1.5806
CAL-33 GDSC1 5.9931 7.7074 3.4294 0.7301
BHY GDSC1 6.0326 7.6476 3.4677 0.5609
SCC-9 GDSC1 6.0423 7.4326 3.549 0.3076
FaDu GDSC1 6.0528 7.4351 3.552 0.2954
BICR 31 GDSC1 6.1823 8.0484 3.3794 0.7831
UPCI-SCC-090 GDSC1 6.1883 8.1881 3.3289 0.9837
HO-1-N-1 GDSC1 6.243 7.6748 3.538 0.2565
BICR 22 GDSC1 6.2631 7.8889 3.47 0.4243
SCC-15 GDSC1 6.2684 8.7351 3.1498 1.7456
Detroit 562 GDSC1 6.293 8.1707 3.3789 0.7062
HSC-4 GDSC1 6.3388 7.8711 3.5045 0.2995
JHU-022 GDSC1 6.375 8.538 3.2745 1.0556
LB771-HNC GDSC1 6.3846 8.3595 3.3459 0.7646
PCI-04B GDSC1 6.4149 8.1681 3.4278 0.4723
BICR 10 GDSC1 6.4449 8.0399 3.4844 0.3074
Ca9-22 GDSC1 6.4723 8.3518 3.3836 0.5781
DOK GDSC1 6.4999 8.5533 3.3206 0.7782
PCI-38 GDSC1 6.547 7.9378 3.5556 0.1403
PCI-06A GDSC1 6.5727 8.7784 3.2662 0.9314
SKN-3 GDSC1 6.6095 8.351 3.436 0.3615
SAS GDSC1 6.6125 9.1858 3.1269 1.4924
PE/CA-PJ15 GDSC1 6.7155 8.3653 3.4695 0.249
KOSC-2 GDSC1 6.7765 8.8909 3.3065 0.6534
BB49-HNC GDSC1 6.9013 8.9095 3.3476 0.468
JHU-029 GDSC1 6.9049 9.3201 3.1997 0.9439
PCI-30 GDSC1 7.0014 8.6241 3.4818 0.1572
OSC-19 GDSC1 7.0304 8.8915 3.4012 0.2917
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
639V GDSC1 4.2341 8.0125 2.1853 13.3082
HT-1197 GDSC1 4.8859 6.3311 3.4637 1.9003
BFTC-905 GDSC1 5.5486 7.1621 3.4477 1.0515
J82 GDSC1 5.7043 7.4499 3.4041 1.0991
KU-19-19 GDSC1 5.7483 7.2817 3.4883 0.6848
CAL-29 GDSC1 5.8437 7.7806 3.3362 1.2828
SW1710 GDSC1 5.8808 8.1083 3.2209 1.841
TCCSUP GDSC1 6.1601 7.8034 3.4611 0.5065
RT-4 GDSC1 6.2279 7.7601 3.5025 0.35
647V GDSC1 6.4097 7.4853 3.6589 0.0444
RT-112 GDSC1 6.5144 7.8021 3.5898 0.0997
T24 GDSC1 6.6026 8.3721 3.426 0.39
SW780 GDSC1 6.6602 8.2062 3.5043 0.1983
UM-UC-3 GDSC1 6.6702 8.1875 3.5141 0.1788
5637 GDSC1 6.6885 9.0467 3.2131 1.0527
HT-1376 GDSC1 7.3035 8.9917 3.4622 0.1295
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVMIU GDSC1 3.5825 7.1493 2.0652 16.6525
JEG-3 GDSC1 4.142 5.242 3.493 3.5127
HT-3 GDSC1 4.5133 9.8615 1.4853 17.1431
HeLa GDSC1 4.7128 6.4801 3.2918 3.4699
SKN GDSC1 4.8421 7.1141 3.0764 4.7369
SiHa GDSC1 5.0178 7.2691 3.1158 4.0329
NT2-D1 GDSC1 5.0205 7.5245 2.9983 4.8734
SW756 GDSC1 5.2238 9.5126 2.1849 10.2279
CAL-39 GDSC1 5.3821 7.2927 3.3128 2.018
JAR GDSC1 5.466 7.1307 3.422 1.2774
C-4-I GDSC1 5.6203 21.52 -3.449 31.9005
C-33 A GDSC1 5.7811 8.1791 3.1417 2.4348
SW962 GDSC1 5.7967 9.7066 2.4688 6.82
NCC-IT GDSC1 5.8082 7.7456 3.3339 1.3336
SW954 GDSC1 5.8585 7.8442 3.3176 1.3595
NEC8 GDSC1 5.922 7.3452 3.5346 0.4061
HEC-1 GDSC1 5.9466 7.1859 3.6002 0.2201
BPH-1 GDSC1 5.9894 8.5015 3.1113 2.3089
MS751 GDSC1 6.0767 7.9183 3.3846 0.8443
SKG-IIIa GDSC1 6.175 7.9111 3.4275 0.6105
DoTc2 4510 GDSC1 6.1869 8.7044 3.1239 1.9781
DSH1 GDSC1 6.3967 8.703 3.2203 1.2729
SiSo GDSC1 6.5429 8.3836 3.3994 0.4915
LB831-BLC GDSC1 6.5772 8.2967 3.4432 0.3566
OMC-1 [Human cervical carcinoma] GDSC1 6.7476 8.3538 3.4848 0.2106
ME-180 GDSC1 6.7511 8.9438 3.2771 0.7676
PA-1 GDSC1 6.8843 8.2915 3.5525 0.0881
Ca Ski GDSC1 6.9061 9.2083 3.2415 0.7928
KGN GDSC1 7.1293 9.1288 3.3547 0.3595
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug

References

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4 Identification of protein tyrosine phosphatase SHP-2 as a new target of perfluoroalkyl acids in HepG2 cells. Arch Toxicol. 2017 Apr;91(4):1697-1707. doi: 10.1007/s00204-016-1836-2. Epub 2016 Aug 29.
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