Details of the Drug

General Information of Drug (ID: DMF27BS)

Drug Name
MMV00/0053
Synonyms PfENR inhibitors, Jacobus; Plasmodium falciparum enoyl acyl carrier protein reductase inhibitors, Jacobus; FAS II inhibitors, Jacobus/MMV; Fatty acid biosynthesis II inhibitors, Jacobus/MMV
Indication
Disease Entry ICD 11 Status REF
Malaria 1F40-1F45 Terminated [1]
Structure 3D Structure is Not Available
3D MOL 2D MOL
Cross-matching ID
TTD ID
D0K1UD

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Fatty acid synthetase I (Bact inhA) TTVTX4N INHA_MYCTU Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Annual report of Medicines for Malaria Venture in 2002.
2 SAR and pharmacophore models for the rhodanine inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase. IUBMB Life. 2010 Mar;62(3):204-13.